CYP2D6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP2D6
Entrez Gene ID	1565
Full Name	cytochrome P450 family 2 subfamily D member 6
Synonyms	CPD6,CYP2D,CYP2D7AP,CYP2D7BP,CYP2D7P2,CYP2D8P2,CYP2DL1,CYPIID6,P450-DB1,P450C2D,P450DB1
General protein information	Preferred Names cytochrome P450 family 2 subfamily D member 6 Names cytochrome P450 2D6 cholesterol 25-hydroxylase cytochrome P450, family 2, subfamily D, polypeptide 6 cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2 cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2 cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1 cytochrome P450-DB1 debrisoquine 4-hydroxylase flavoprotein-linked monooxygenase microsomal monooxygenase nonfunctional cytochrome P450 2D6 xenobiotic monooxygenase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q13.2
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014].
Disorder MIM:	124030
Disorder Html:	{Debrisoquine sensitivity}, 608902 (3); {Codeine sensitivity}, 608902 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011529966.2	XP_011528268.1	cytochrome P450 2D6 isoform X1
NM_001025161.2	NP_001020332.2	cytochrome P450 2D6 isoform 2
XM_011529968.2	XP_011528270.1	cytochrome P450 2D6 isoform X2
XM_011529970.2	XP_011528272.1	cytochrome P450 2D6 isoform X3
NM_001025161.3	NP_001020332.2	cytochrome P450 2D6 isoform 2
NM_000106.6	NP_000097.3	cytochrome P450 2D6 isoform 1
NM_000106.5	NP_000097.3	cytochrome P450 2D6 isoform 1
XM_011529972.2	XP_011528274.1	cytochrome P450 2D6 isoform X4

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CYP2D6	NP_001035712.1
	CYP2D6	NP_001035308.1
Homo sapiens (human)	CYP2D6	NP_000097.3
Xenopus tropicalis (tropical clawed frog)	LOC100495518	XP_002933809.2
Xenopus tropicalis (tropical clawed frog)	cyp2d6	NP_001015719.1
Xenopus tropicalis (tropical clawed frog)	LOC100495359	XP_002933808.1
Xenopus tropicalis (tropical clawed frog)	LOC101731511	XP_004913819.1
Rattus norvegicus (Norway rat)	Cyp2d3	NP_775116.1
Gallus gallus (chicken)	CYP2D6	NP_001182486.1

Gene Ontology

The following CYP2D6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP2D6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28716	NM_000106.6 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu28723	NM_001025161.3 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu57147	XM_011529966.2 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu57148	XM_011529968.2 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu57150	XM_011529970.2 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu57152	XM_011529972.2 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu28723	NM_001025161.2	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu28716	NM_000106.5	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP2D6 ( NM_000106.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_000097.3 Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28716
Clone ID Related Accession (Same CDS sequence)	NM_000106.6 , NM_000106.5
Accession Version	NM_000106.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-30
Organism	Homo sapiens(human)
Product	cytochrome P450 2D6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC075023.2 and AW297258.1. This sequence is a reference standard in the RefSeqGene project. On Jul 27, 2018 this sequence version replaced NM_000106.5. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC075023.2, M20403.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000645361.2/ ENSP00000496150.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCAAGG GGAACCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGCT 
GACCTGTTCT CTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ATCCGGATGT GCAGCGCCGT GTCCAACAGG AGATCGACGA CGTGATAGGG 
CAGGTGCGGC GACCAGAGAT GGGTGACCAG GCTCACATGC CCTACACCAC TGCCGTGATT 
CATGAGGTGC AGCGCTTTGG GGACATCGTC CCCCTGGGTG TGACCCATAT GACATCCCGT 
GACATCGAAG TACAGGGCTT CCGCATCCCT AAGGGAACGA CACTCATCAC CAACCTGTCA 
TCGGTGCTGA AGGATGAGGC CGTCTGGGAG AAGCCCTTCC GCTTCCACCC CGAACACTTC 
CTGGATGCCC AGGGCCACTT TGTGAAGCCG GAGGCCTTCC TGCCTTTCTC AGCAGGCCGC 
CGTGCATGCC TCGGGGAGCC CCTGGCCCGC ATGGAGCTCT TCCTCTTCTT CACCTCCCTG 
CTGCAGCACT TCAGCTTCTC GGTGCCCACT GGACAGCCCC GGCCCAGCCA CCATGGTGTC 
TTTGCTTTCC TGGTGAGCCC ATCCCCCTAT GAGCTTTGTG CTGTGCCCCG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000097.3
CDS	20..1513
Translation	MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR

Target ORF information:

RefSeq Version	NM_000106.6
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000106.6

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCAAGG GGAACCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGCT 
GACCTGTTCT CTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ATCCGGATGT GCAGCGCCGT GTCCAACAGG AGATCGACGA CGTGATAGGG 
CAGGTGCGGC GACCAGAGAT GGGTGACCAG GCTCACATGC CCTACACCAC TGCCGTGATT 
CATGAGGTGC AGCGCTTTGG GGACATCGTC CCCCTGGGTG TGACCCATAT GACATCCCGT 
GACATCGAAG TACAGGGCTT CCGCATCCCT AAGGGAACGA CACTCATCAC CAACCTGTCA 
TCGGTGCTGA AGGATGAGGC CGTCTGGGAG AAGCCCTTCC GCTTCCACCC CGAACACTTC 
CTGGATGCCC AGGGCCACTT TGTGAAGCCG GAGGCCTTCC TGCCTTTCTC AGCAGGCCGC 
CGTGCATGCC TCGGGGAGCC CCTGGCCCGC ATGGAGCTCT TCCTCTTCTT CACCTCCCTG 
CTGCAGCACT TCAGCTTCTC GGTGCCCACT GGACAGCCCC GGCCCAGCCA CCATGGTGTC 
TTTGCTTTCC TGGTGAGCCC ATCCCCCTAT GAGCTTTGTG CTGTGCCCCG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D6 ( NM_000106.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000097.3 Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28716
Clone ID Related Accession (Same CDS sequence)	NM_000106.6 , NM_000106.5
Accession Version	NM_000106.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1494bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	cytochrome P450 2D6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB124853.1, BC075023.2 and AY663390.1. This sequence is a reference standard in the RefSeqGene project. On Jun 22, 2012 this sequence version replaced NM_000106.4. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M20403.1, X08006.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCAAGG GGAACCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGCT 
GACCTGTTCT CTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ATCCGGATGT GCAGCGCCGT GTCCAACAGG AGATCGACGA CGTGATAGGG 
CAGGTGCGGC GACCAGAGAT GGGTGACCAG GCTCACATGC CCTACACCAC TGCCGTGATT 
CATGAGGTGC AGCGCTTTGG GGACATCGTC CCCCTGGGTG TGACCCATAT GACATCCCGT 
GACATCGAAG TACAGGGCTT CCGCATCCCT AAGGGAACGA CACTCATCAC CAACCTGTCA 
TCGGTGCTGA AGGATGAGGC CGTCTGGGAG AAGCCCTTCC GCTTCCACCC CGAACACTTC 
CTGGATGCCC AGGGCCACTT TGTGAAGCCG GAGGCCTTCC TGCCTTTCTC AGCAGGCCGC 
CGTGCATGCC TCGGGGAGCC CCTGGCCCGC ATGGAGCTCT TCCTCTTCTT CACCTCCCTG 
CTGCAGCACT TCAGCTTCTC GGTGCCCACT GGACAGCCCC GGCCCAGCCA CCATGGTGTC 
TTTGCTTTCC TGGTGAGCCC ATCCCCCTAT GAGCTTTGTG CTGTGCCCCG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000097.3
CDS	91..1584
Translation	MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR

Target ORF information:

RefSeq Version	NM_000106.5
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000106.5

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCAAGG GGAACCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGCT 
GACCTGTTCT CTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ATCCGGATGT GCAGCGCCGT GTCCAACAGG AGATCGACGA CGTGATAGGG 
CAGGTGCGGC GACCAGAGAT GGGTGACCAG GCTCACATGC CCTACACCAC TGCCGTGATT 
CATGAGGTGC AGCGCTTTGG GGACATCGTC CCCCTGGGTG TGACCCATAT GACATCCCGT 
GACATCGAAG TACAGGGCTT CCGCATCCCT AAGGGAACGA CACTCATCAC CAACCTGTCA 
TCGGTGCTGA AGGATGAGGC CGTCTGGGAG AAGCCCTTCC GCTTCCACCC CGAACACTTC 
CTGGATGCCC AGGGCCACTT TGTGAAGCCG GAGGCCTTCC TGCCTTTCTC AGCAGGCCGC 
CGTGCATGCC TCGGGGAGCC CCTGGCCCGC ATGGAGCTCT TCCTCTTCTT CACCTCCCTG 
CTGCAGCACT TCAGCTTCTC GGTGCCCACT GGACAGCCCC GGCCCAGCCA CCATGGTGTC 
TTTGCTTTCC TGGTGAGCCC ATCCCCCTAT GAGCTTTGTG CTGTGCCCCG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D6 ( NM_001025161.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020332.2 Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28723
Clone ID Related Accession (Same CDS sequence)	NM_001025161.2 , NM_001025161.3
Accession Version	NM_001025161.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	cytochrome P450 2D6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB124853.1, BC066877.1, BC075023.2 and AY663390.1. On Jun 22, 2012 this sequence version replaced NM_001025161.1. Transcript Variant: This variant (2) lacks an in-frame exon in the CDS, as compared to variant 1, which results in a shorter isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC106757.1, CR456430.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGACGCCCC 
TTTCGCCCCA ACGGTCTCTT GGACAAAGCC GTGAGCAACG TGATCGCCTC CCTCACCTGC 
GGGCGCCGCT TCGAGTACGA CGACCCTCGC TTCCTCAGGC TGCTGGACCT AGCTCAGGAG 
GGACTGAAGG AGGAGTCGGG CTTTCTGCGC GAGGTGCTGA ATGCTGTCCC CGTCCTCCTG 
CATATCCCAG CGCTGGCTGG CAAGGTCCTA CGCTTCCAAA AGGCTTTCCT GACCCAGCTG 
GATGAGCTGC TAACTGAGCA CAGGATGACC TGGGACCCAG CCCAGCCCCC CCGAGACCTG 
ACTGAGGCCT TCCTGGCAGA GATGGAGAAG GCCAAGGGGA ACCCTGAGAG CAGCTTCAAT 
GATGAGAACC TGCGCATAGT GGTGGCTGAC CTGTTCTCTG CCGGGATGGT GACCACCTCG 
ACCACGCTGG CCTGGGGCCT CCTGCTCATG ATCCTACATC CGGATGTGCA GCGCCGTGTC 
CAACAGGAGA TCGACGACGT GATAGGGCAG GTGCGGCGAC CAGAGATGGG TGACCAGGCT 
CACATGCCCT ACACCACTGC CGTGATTCAT GAGGTGCAGC GCTTTGGGGA CATCGTCCCC 
CTGGGTGTGA CCCATATGAC ATCCCGTGAC ATCGAAGTAC AGGGCTTCCG CATCCCTAAG 
GGAACGACAC TCATCACCAA CCTGTCATCG GTGCTGAAGG ATGAGGCCGT CTGGGAGAAG 
CCCTTCCGCT TCCACCCCGA ACACTTCCTG GATGCCCAGG GCCACTTTGT GAAGCCGGAG 
GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT GCATGCCTCG GGGAGCCCCT GGCCCGCATG 
GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG CAGCACTTCA GCTTCTCGGT GCCCACTGGA 
CAGCCCCGGC CCAGCCACCA TGGTGTCTTT GCTTTCCTGG TGAGCCCATC CCCCTATGAG 
CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020332.2
CDS	91..1431
Translation	MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR

Target ORF information:

RefSeq Version	NM_001025161.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025161.2

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGACGCCCC 
TTTCGCCCCA ACGGTCTCTT GGACAAAGCC GTGAGCAACG TGATCGCCTC CCTCACCTGC 
GGGCGCCGCT TCGAGTACGA CGACCCTCGC TTCCTCAGGC TGCTGGACCT AGCTCAGGAG 
GGACTGAAGG AGGAGTCGGG CTTTCTGCGC GAGGTGCTGA ATGCTGTCCC CGTCCTCCTG 
CATATCCCAG CGCTGGCTGG CAAGGTCCTA CGCTTCCAAA AGGCTTTCCT GACCCAGCTG 
GATGAGCTGC TAACTGAGCA CAGGATGACC TGGGACCCAG CCCAGCCCCC CCGAGACCTG 
ACTGAGGCCT TCCTGGCAGA GATGGAGAAG GCCAAGGGGA ACCCTGAGAG CAGCTTCAAT 
GATGAGAACC TGCGCATAGT GGTGGCTGAC CTGTTCTCTG CCGGGATGGT GACCACCTCG 
ACCACGCTGG CCTGGGGCCT CCTGCTCATG ATCCTACATC CGGATGTGCA GCGCCGTGTC 
CAACAGGAGA TCGACGACGT GATAGGGCAG GTGCGGCGAC CAGAGATGGG TGACCAGGCT 
CACATGCCCT ACACCACTGC CGTGATTCAT GAGGTGCAGC GCTTTGGGGA CATCGTCCCC 
CTGGGTGTGA CCCATATGAC ATCCCGTGAC ATCGAAGTAC AGGGCTTCCG CATCCCTAAG 
GGAACGACAC TCATCACCAA CCTGTCATCG GTGCTGAAGG ATGAGGCCGT CTGGGAGAAG 
CCCTTCCGCT TCCACCCCGA ACACTTCCTG GATGCCCAGG GCCACTTTGT GAAGCCGGAG 
GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT GCATGCCTCG GGGAGCCCCT GGCCCGCATG 
GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG CAGCACTTCA GCTTCTCGGT GCCCACTGGA 
CAGCCCCGGC CCAGCCACCA TGGTGTCTTT GCTTTCCTGG TGAGCCCATC CCCCTATGAG 
CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D6 ( NM_001025161.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020332.2 Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 2, mRNA.

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CloneID	OHu28723
Clone ID Related Accession (Same CDS sequence)	NM_001025161.2 , NM_001025161.3
Accession Version	NM_001025161.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Homo sapiens(human)
Product	cytochrome P450 2D6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB124853.1, BC066877.1, BC075023.2 and AY663390.1. On May 31, 2019 this sequence version replaced NM_001025161.2. Transcript Variant: This variant (2) lacks an in-frame exon in the CDS, as compared to variant 1, which results in a shorter isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC106757.1, CR456430.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGACGCCCC 
TTTCGCCCCA ACGGTCTCTT GGACAAAGCC GTGAGCAACG TGATCGCCTC CCTCACCTGC 
GGGCGCCGCT TCGAGTACGA CGACCCTCGC TTCCTCAGGC TGCTGGACCT AGCTCAGGAG 
GGACTGAAGG AGGAGTCGGG CTTTCTGCGC GAGGTGCTGA ATGCTGTCCC CGTCCTCCTG 
CATATCCCAG CGCTGGCTGG CAAGGTCCTA CGCTTCCAAA AGGCTTTCCT GACCCAGCTG 
GATGAGCTGC TAACTGAGCA CAGGATGACC TGGGACCCAG CCCAGCCCCC CCGAGACCTG 
ACTGAGGCCT TCCTGGCAGA GATGGAGAAG GCCAAGGGGA ACCCTGAGAG CAGCTTCAAT 
GATGAGAACC TGCGCATAGT GGTGGCTGAC CTGTTCTCTG CCGGGATGGT GACCACCTCG 
ACCACGCTGG CCTGGGGCCT CCTGCTCATG ATCCTACATC CGGATGTGCA GCGCCGTGTC 
CAACAGGAGA TCGACGACGT GATAGGGCAG GTGCGGCGAC CAGAGATGGG TGACCAGGCT 
CACATGCCCT ACACCACTGC CGTGATTCAT GAGGTGCAGC GCTTTGGGGA CATCGTCCCC 
CTGGGTGTGA CCCATATGAC ATCCCGTGAC ATCGAAGTAC AGGGCTTCCG CATCCCTAAG 
GGAACGACAC TCATCACCAA CCTGTCATCG GTGCTGAAGG ATGAGGCCGT CTGGGAGAAG 
CCCTTCCGCT TCCACCCCGA ACACTTCCTG GATGCCCAGG GCCACTTTGT GAAGCCGGAG 
GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT GCATGCCTCG GGGAGCCCCT GGCCCGCATG 
GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG CAGCACTTCA GCTTCTCGGT GCCCACTGGA 
CAGCCCCGGC CCAGCCACCA TGGTGTCTTT GCTTTCCTGG TGAGCCCATC CCCCTATGAG 
CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020332.2
CDS	20..1360
Translation	MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR

Target ORF information:

RefSeq Version	NM_001025161.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025161.3

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGACGCCCC 
TTTCGCCCCA ACGGTCTCTT GGACAAAGCC GTGAGCAACG TGATCGCCTC CCTCACCTGC 
GGGCGCCGCT TCGAGTACGA CGACCCTCGC TTCCTCAGGC TGCTGGACCT AGCTCAGGAG 
GGACTGAAGG AGGAGTCGGG CTTTCTGCGC GAGGTGCTGA ATGCTGTCCC CGTCCTCCTG 
CATATCCCAG CGCTGGCTGG CAAGGTCCTA CGCTTCCAAA AGGCTTTCCT GACCCAGCTG 
GATGAGCTGC TAACTGAGCA CAGGATGACC TGGGACCCAG CCCAGCCCCC CCGAGACCTG 
ACTGAGGCCT TCCTGGCAGA GATGGAGAAG GCCAAGGGGA ACCCTGAGAG CAGCTTCAAT 
GATGAGAACC TGCGCATAGT GGTGGCTGAC CTGTTCTCTG CCGGGATGGT GACCACCTCG 
ACCACGCTGG CCTGGGGCCT CCTGCTCATG ATCCTACATC CGGATGTGCA GCGCCGTGTC 
CAACAGGAGA TCGACGACGT GATAGGGCAG GTGCGGCGAC CAGAGATGGG TGACCAGGCT 
CACATGCCCT ACACCACTGC CGTGATTCAT GAGGTGCAGC GCTTTGGGGA CATCGTCCCC 
CTGGGTGTGA CCCATATGAC ATCCCGTGAC ATCGAAGTAC AGGGCTTCCG CATCCCTAAG 
GGAACGACAC TCATCACCAA CCTGTCATCG GTGCTGAAGG ATGAGGCCGT CTGGGAGAAG 
CCCTTCCGCT TCCACCCCGA ACACTTCCTG GATGCCCAGG GCCACTTTGT GAAGCCGGAG 
GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT GCATGCCTCG GGGAGCCCCT GGCCCGCATG 
GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG CAGCACTTCA GCTTCTCGGT GCCCACTGGA 
CAGCCCCGGC CCAGCCACCA TGGTGTCTTT GCTTTCCTGG TGAGCCCATC CCCCTATGAG 
CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D6 ( XM_011529966.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528268.1 Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X1, mRNA.

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CloneID	OHu57147
Clone ID Related Accession (Same CDS sequence)	XM_011529966.2
Accession Version	XM_011529966.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cytochrome P450 2D6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529966.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCAAGG GGAACCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGCT 
GACCTGTTCT CTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ATCCGGATGT GCAGCGCCGT GTCCAACAGG AGATCGACGA CGTGATAGGG 
CAGGTGCGGC GACCAGAGAT GGGTGACCAG GCTCACATGC CCTACACCAC TGCCGTGATT 
CATGAGGTGC AGCGCTTTGG GGACATCGTC CCCCTGGGTG TGACCCATAT GACATCCCGT 
GACATCGAAG TACAGGGCTT CCGCATCCCT AAGGGAACGA CACTCATCAC CAACCTGTCA 
TCGGTGCTGA AGGATGAGGC CGTCTGGGAG AAGCCCTTCC GCTTCCACCC CGAACACTTC 
CTGGATGCCC AGGGCCACTT TGTGAAGCCG GAGGCCTTCC TGCCTTTCTC AGCAGGCCGC 
CGTGCATGCC TCGGGGAGCC CCTGGCCCGC ATGGAGCTCT TCCTCTTCTT CACCTCCCTG 
CTGCAGCACT TCAGCTTCTC GGTGCCCACT GGACAGCCCC GGCCCAGCCA CCATGGTGTC 
TTTGCTTTCC TGGACTGGCT ACCTCTCTGG GCCCTCAGGG ATGCTGCTGT ACAGACCCCT 
GACCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528268.1
CDS	85..1593
Translation	MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLDWLPLWALRDAAVQTPDQ

Target ORF information:

RefSeq Version	XM_011529966.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529966.2

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCAAGG GGAACCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGCT 
GACCTGTTCT CTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ATCCGGATGT GCAGCGCCGT GTCCAACAGG AGATCGACGA CGTGATAGGG 
CAGGTGCGGC GACCAGAGAT GGGTGACCAG GCTCACATGC CCTACACCAC TGCCGTGATT 
CATGAGGTGC AGCGCTTTGG GGACATCGTC CCCCTGGGTG TGACCCATAT GACATCCCGT 
GACATCGAAG TACAGGGCTT CCGCATCCCT AAGGGAACGA CACTCATCAC CAACCTGTCA 
TCGGTGCTGA AGGATGAGGC CGTCTGGGAG AAGCCCTTCC GCTTCCACCC CGAACACTTC 
CTGGATGCCC AGGGCCACTT TGTGAAGCCG GAGGCCTTCC TGCCTTTCTC AGCAGGCCGC 
CGTGCATGCC TCGGGGAGCC CCTGGCCCGC ATGGAGCTCT TCCTCTTCTT CACCTCCCTG 
CTGCAGCACT TCAGCTTCTC GGTGCCCACT GGACAGCCCC GGCCCAGCCA CCATGGTGTC 
TTTGCTTTCC TGGACTGGCT ACCTCTCTGG GCCCTCAGGG ATGCTGCTGT ACAGACCCCT 
GACCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D6 ( XM_011529968.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528270.1 Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X2, mRNA.

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CloneID	OHu57148
Clone ID Related Accession (Same CDS sequence)	XM_011529968.2
Accession Version	XM_011529968.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cytochrome P450 2D6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529968.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCAAGG GGAACCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGCT 
GACCTGTTCT CTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ATCCGGATGT GCAGCGCCGT GTCCAACAGG AGATCGACGA CGTGATAGGG 
CAGGTGCGGC GACCAGAGAT GGGTGACCAG GCTCACATGC CCTACACCAC TGCCGTGATT 
CATGAGGTGC AGCGCTTTGG GGACATCGTC CCCCTGGGTG TGACCCATAT GACATCCCGT 
GACATCGAAG TACAGGGCTT CCGCATCCCT AAGGGAACGA CACTCATCAC CAACCTGTCA 
TCGGTGCTGA AGGATGAGGC CGTCTGGGAG AAGCCCTTCC GCTTCCACCC CGAACACTTC 
CTGGATGCCC AGGGCCACTT TGTGAAGCCG GAGGCCTTCC TGCCTTTCTC AGCAGGCCGC 
CGTGCATGCC TCGGGGAGCC CCTGGCCCGC ATGGAGCTCT TCCTCTTCTT CACCTCCCTG 
CTGCAGCACT TCAGCTTCTC GGTGCCCACT GGACAGCCCC GGCCCAGCCA CCATGGTGTC 
TTTGCTTTCC TGGGATGCTG CTGTACAGAC CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528270.1
CDS	85..1560
Translation	MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLGCCCTDP

Target ORF information:

RefSeq Version	XM_011529968.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529968.2

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCAAGG GGAACCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGCT 
GACCTGTTCT CTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ATCCGGATGT GCAGCGCCGT GTCCAACAGG AGATCGACGA CGTGATAGGG 
CAGGTGCGGC GACCAGAGAT GGGTGACCAG GCTCACATGC CCTACACCAC TGCCGTGATT 
CATGAGGTGC AGCGCTTTGG GGACATCGTC CCCCTGGGTG TGACCCATAT GACATCCCGT 
GACATCGAAG TACAGGGCTT CCGCATCCCT AAGGGAACGA CACTCATCAC CAACCTGTCA 
TCGGTGCTGA AGGATGAGGC CGTCTGGGAG AAGCCCTTCC GCTTCCACCC CGAACACTTC 
CTGGATGCCC AGGGCCACTT TGTGAAGCCG GAGGCCTTCC TGCCTTTCTC AGCAGGCCGC 
CGTGCATGCC TCGGGGAGCC CCTGGCCCGC ATGGAGCTCT TCCTCTTCTT CACCTCCCTG 
CTGCAGCACT TCAGCTTCTC GGTGCCCACT GGACAGCCCC GGCCCAGCCA CCATGGTGTC 
TTTGCTTTCC TGGGATGCTG CTGTACAGAC CCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D6 ( XM_011529970.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528272.1 Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X3, mRNA.

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CloneID	OHu57150
Clone ID Related Accession (Same CDS sequence)	XM_011529970.2
Accession Version	XM_011529970.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cytochrome P450 2D6 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529970.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGACGCCCC 
TTTCGCCCCA ACGGTCTCTT GGACAAAGCC GTGAGCAACG TGATCGCCTC CCTCACCTGC 
GGGCGCCGCT TCGAGTACGA CGACCCTCGC TTCCTCAGGC TGCTGGACCT AGCTCAGGAG 
GGACTGAAGG AGGAGTCGGG CTTTCTGCGC GAGGTGCTGA ATGCTGTCCC CGTCCTCCTG 
CATATCCCAG CGCTGGCTGG CAAGGTCCTA CGCTTCCAAA AGGCTTTCCT GACCCAGCTG 
GATGAGCTGC TAACTGAGCA CAGGATGACC TGGGACCCAG CCCAGCCCCC CCGAGACCTG 
ACTGAGGCCT TCCTGGCAGA GATGGAGAAG GCCAAGGGGA ACCCTGAGAG CAGCTTCAAT 
GATGAGAACC TGCGCATAGT GGTGGCTGAC CTGTTCTCTG CCGGGATGGT GACCACCTCG 
ACCACGCTGG CCTGGGGCCT CCTGCTCATG ATCCTACATC CGGATGTGCA GCGCCGTGTC 
CAACAGGAGA TCGACGACGT GATAGGGCAG GTGCGGCGAC CAGAGATGGG TGACCAGGCT 
CACATGCCCT ACACCACTGC CGTGATTCAT GAGGTGCAGC GCTTTGGGGA CATCGTCCCC 
CTGGGTGTGA CCCATATGAC ATCCCGTGAC ATCGAAGTAC AGGGCTTCCG CATCCCTAAG 
GGAACGACAC TCATCACCAA CCTGTCATCG GTGCTGAAGG ATGAGGCCGT CTGGGAGAAG 
CCCTTCCGCT TCCACCCCGA ACACTTCCTG GATGCCCAGG GCCACTTTGT GAAGCCGGAG 
GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT GCATGCCTCG GGGAGCCCCT GGCCCGCATG 
GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG CAGCACTTCA GCTTCTCGGT GCCCACTGGA 
CAGCCCCGGC CCAGCCACCA TGGTGTCTTT GCTTTCCTGG ACTGGCTACC TCTCTGGGCC 
CTCAGGGATG CTGCTGTACA GACCCCTGAC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528272.1
CDS	85..1440
Translation	MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLDWLPLWALRDAAVQTPDQ

Target ORF information:

RefSeq Version	XM_011529970.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529970.2

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGACGCCCC 
TTTCGCCCCA ACGGTCTCTT GGACAAAGCC GTGAGCAACG TGATCGCCTC CCTCACCTGC 
GGGCGCCGCT TCGAGTACGA CGACCCTCGC TTCCTCAGGC TGCTGGACCT AGCTCAGGAG 
GGACTGAAGG AGGAGTCGGG CTTTCTGCGC GAGGTGCTGA ATGCTGTCCC CGTCCTCCTG 
CATATCCCAG CGCTGGCTGG CAAGGTCCTA CGCTTCCAAA AGGCTTTCCT GACCCAGCTG 
GATGAGCTGC TAACTGAGCA CAGGATGACC TGGGACCCAG CCCAGCCCCC CCGAGACCTG 
ACTGAGGCCT TCCTGGCAGA GATGGAGAAG GCCAAGGGGA ACCCTGAGAG CAGCTTCAAT 
GATGAGAACC TGCGCATAGT GGTGGCTGAC CTGTTCTCTG CCGGGATGGT GACCACCTCG 
ACCACGCTGG CCTGGGGCCT CCTGCTCATG ATCCTACATC CGGATGTGCA GCGCCGTGTC 
CAACAGGAGA TCGACGACGT GATAGGGCAG GTGCGGCGAC CAGAGATGGG TGACCAGGCT 
CACATGCCCT ACACCACTGC CGTGATTCAT GAGGTGCAGC GCTTTGGGGA CATCGTCCCC 
CTGGGTGTGA CCCATATGAC ATCCCGTGAC ATCGAAGTAC AGGGCTTCCG CATCCCTAAG 
GGAACGACAC TCATCACCAA CCTGTCATCG GTGCTGAAGG ATGAGGCCGT CTGGGAGAAG 
CCCTTCCGCT TCCACCCCGA ACACTTCCTG GATGCCCAGG GCCACTTTGT GAAGCCGGAG 
GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT GCATGCCTCG GGGAGCCCCT GGCCCGCATG 
GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG CAGCACTTCA GCTTCTCGGT GCCCACTGGA 
CAGCCCCGGC CCAGCCACCA TGGTGTCTTT GCTTTCCTGG ACTGGCTACC TCTCTGGGCC 
CTCAGGGATG CTGCTGTACA GACCCCTGAC CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D6 ( XM_011529972.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011528274.1 Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu57152
Clone ID Related Accession (Same CDS sequence)	XM_011529972.2
Accession Version	XM_011529972.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 873bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cytochrome P450 2D6 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529972.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCGTGT CCAACAGGAG ATCGACGACG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011528274.1
CDS	85..957
Translation	MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAVSNRRSTT

Target ORF information:

RefSeq Version	XM_011529972.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 6 (CYP2D6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011529972.2

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC GTGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCGCCA ACGCTGGGCT GCACGCTACC CACCAGGCCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG CTGGTGACCC ACGGCGAGGA CACCGCCGAC 
CGCCCGCCTG TGCCCATCAC CCAGATCCTG GGTTTCGGGC CGCGTTCCCA AGGGGTGTTC 
CTGGCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCAACCA CTCCGGACGC CCCTTTCGCC CCAACGGTCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTTCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CTGCATATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC CCCCCGAGAC CTGACTGAGG CCTTCCTGGC AGAGATGGAG 
AAGGCCGTGT CCAACAGGAG ATCGACGACG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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CYP2D6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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