CYP2D7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP2D7
Entrez Gene ID	1564
Full Name	cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
Synonyms	CYP2D,CYP2D7AP,CYP2D7P,CYP2D7P1,CYP2D@,P450C2D,P450DB1,RNA40057
General protein information	Preferred Names cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) Names putative cytochrome P450 2D7 Putative cytochrome P450 2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 1 cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 1 cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing) cluster
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q13.2
Summary	This gene is a member of the cytochrome P450 gene superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is a segregating pseudogene, where some individuals may have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. In this case, the functional allele is thought to be rare. This locus is part of a cluster of cytochrome P450 genes on chromosome 22. [provided by RefSeq, Jan 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001348386.2	NP_001335315.1	putative cytochrome P450 2D7
NM_001348386.3	NP_001335315.1	putative cytochrome P450 2D7
NM_001348386.1	NP_001335315.1	putative cytochrome P450 2D7

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.
Wang J, Xie H, Ling Q, Lu D, Lv Z, Zhuang R, Liu Z, Wei X, Zhou L, Xu X, Zheng S
Translational research : the journal of laboratory and clinical medicine168107-121(2016 Feb)

CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.
Gaedigk A, Twist GP, Leeder JS
Pharmacogenomics13(1)91-111(2012 Jan)

Expression and functional analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 isozymes.
Zhang WY, Tu YB, Haining RL, Yu AM
Drug metabolism and disposition: the biological fate of chemicals37(1)1-4(2009 Jan)

Frequency of the frame-shifting CYP2D7 138delT polymorphism in a large, ethnically diverse sample population.
Bhathena A, Mueller T, Grimm DR, Idler K, Tsurutani A, Spear BB, Katz DA
Drug metabolism and disposition: the biological fate of chemicals35(8)1251-3(2007 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of genotype prevalence. (HuGE Navigator)
Title: Frequency of the frame-shifting CYP2D7 138delT polymorphism in a large, ethnically diverse sample population.

Observational study of gene-disease association. (HuGE Navigator)
Title: Polymorphism of metabolic genes and susceptibility to occupational chronic manganism.

The following CYP2D7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP2D7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu102235	NM_001348386.3 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu102235	NM_001348386.2	Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu102235	NM_001348386.1	Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP2D7 ( NM_001348386.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001335315.1 Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 3, mRNA.

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CloneID	OHu102235
Clone ID Related Accession (Same CDS sequence)	NM_001348386.2 , NM_001348386.3 , NM_001348386.1
Accession Version	NM_001348386.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-26
Organism	Homo sapiens(human)
Product	putative cytochrome P450 2D7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY220845.1, BC108679.1, AC254562.1 and X16866.1. On Oct 31, 2018 this sequence version replaced NM_001348386.1. Transcript Variant: This variant (3) uses an alternate splice site resulting in a longer transcript compared to variant 1. This variant represents the functional allele encoding the full-length protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY220845.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 15051713 ##RefSeq-Attributes-END##

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC ATGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCACCA ACGCTGGGCT GCACGCTACC CGCCAGGTCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG ATGGTGACCC GCGGCGAGGA CACGGCCGAC 
CGCCCGCCTG CGCCCATCTA CCAGGTCCTG GGCTTCGGGC CGCGTTCCCA AGGGGTGATC 
CTGTCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCGACCA AGCCGGACGC CCCTTTCGCC CCAACGGCCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTCCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CCGCACATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC ACCCCGAGAC CTGACTGAGG CCTTCCTGGC AAAGAAGGAG 
AAGGCCAAGG GGAGCCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGGT 
AACCTGTTCC TTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ACCTGGATGT GCAGCGAGGA AGGAGAGTGT CCCCTGGGTG CTCACCCATT 
GTGGGGACGC ATGTCTGTCC AGTCCGTGTC CAACAGGAGA TCGACGACGT GATAGGGCAG 
GTGCGGCGAC CAGAGATGGG TGACCAGGCT CACATGCCCT GCACCACTGC CGTGATTCAC 
GAGGTGCAGC ACTTTGGGGA CATCGTCCCC CTGGGTGTGA CCCATATGAC ATCCCGTGAC 
ATCGAAGTAC AGGGCTTCCG CATCCCTAAG GGAACGACAC TCATCACCAA CCTGTCATCG 
GTGCTGAAGG ATGAGGCCGT CTGGAAGAAG CCCTTCCGCT TCCACCCCGA ACACTTCCTG 
GATGCCCAGG GCCACTTTGT GAAGCCGGAG GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT 
GCATGCCTCG GGGAGCCCCT GGCCCGCATG GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG 
CAGCACTTCA GCTTCTCCGT GGCCGCCGGA CAGCCCCGGC CCAGCCACTC TCGTGTCGTC 
AGCTTTCTGG TGACCCCATC CCCCTACGAG CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001335315.1
CDS	20..1570
Translation	MGLEALVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLPHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEKAKGSPESSFNDENLRIVVGNLFLAGMVTTSTTLAWGLLLMILHLDVQRGRRVSPGCSPIVGTHVCPVRVQQEIDDVIGQVRRPEMGDQAHMPCTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR

Target ORF information:

RefSeq Version	NM_001348386.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001348386.2

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC ATGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCACCA ACGCTGGGCT GCACGCTACC CGCCAGGTCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG ATGGTGACCC GCGGCGAGGA CACGGCCGAC 
CGCCCGCCTG CGCCCATCTA CCAGGTCCTG GGCTTCGGGC CGCGTTCCCA AGGGGTGATC 
CTGTCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCGACCA AGCCGGACGC CCCTTTCGCC CCAACGGCCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTCCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CCGCACATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC ACCCCGAGAC CTGACTGAGG CCTTCCTGGC AAAGAAGGAG 
AAGGCCAAGG GGAGCCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGGT 
AACCTGTTCC TTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ACCTGGATGT GCAGCGAGGA AGGAGAGTGT CCCCTGGGTG CTCACCCATT 
GTGGGGACGC ATGTCTGTCC AGTCCGTGTC CAACAGGAGA TCGACGACGT GATAGGGCAG 
GTGCGGCGAC CAGAGATGGG TGACCAGGCT CACATGCCCT GCACCACTGC CGTGATTCAC 
GAGGTGCAGC ACTTTGGGGA CATCGTCCCC CTGGGTGTGA CCCATATGAC ATCCCGTGAC 
ATCGAAGTAC AGGGCTTCCG CATCCCTAAG GGAACGACAC TCATCACCAA CCTGTCATCG 
GTGCTGAAGG ATGAGGCCGT CTGGAAGAAG CCCTTCCGCT TCCACCCCGA ACACTTCCTG 
GATGCCCAGG GCCACTTTGT GAAGCCGGAG GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT 
GCATGCCTCG GGGAGCCCCT GGCCCGCATG GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG 
CAGCACTTCA GCTTCTCCGT GGCCGCCGGA CAGCCCCGGC CCAGCCACTC TCGTGTCGTC 
AGCTTTCTGG TGACCCCATC CCCCTACGAG CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D7 ( NM_001348386.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001335315.1 Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu102235
Clone ID Related Accession (Same CDS sequence)	NM_001348386.2 , NM_001348386.3 , NM_001348386.1
Accession Version	NM_001348386.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	putative cytochrome P450 2D7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY220845.1, BC108679.1, AC254562.1 and X16866.1. On Jun 2, 2019 this sequence version replaced NM_001348386.2. Transcript Variant: This variant (3) uses an alternate splice site resulting in a longer transcript compared to variant 1. This variant represents the functional allele encoding the full-length protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY220845.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154529, SAMEA2155628 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 15051713 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC ATGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCACCA ACGCTGGGCT GCACGCTACC CGCCAGGTCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG ATGGTGACCC GCGGCGAGGA CACGGCCGAC 
CGCCCGCCTG CGCCCATCTA CCAGGTCCTG GGCTTCGGGC CGCGTTCCCA AGGGGTGATC 
CTGTCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCGACCA AGCCGGACGC CCCTTTCGCC CCAACGGCCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTCCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CCGCACATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC ACCCCGAGAC CTGACTGAGG CCTTCCTGGC AAAGAAGGAG 
AAGGCCAAGG GGAGCCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGGT 
AACCTGTTCC TTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ACCTGGATGT GCAGCGAGGA AGGAGAGTGT CCCCTGGGTG CTCACCCATT 
GTGGGGACGC ATGTCTGTCC AGTCCGTGTC CAACAGGAGA TCGACGACGT GATAGGGCAG 
GTGCGGCGAC CAGAGATGGG TGACCAGGCT CACATGCCCT GCACCACTGC CGTGATTCAC 
GAGGTGCAGC ACTTTGGGGA CATCGTCCCC CTGGGTGTGA CCCATATGAC ATCCCGTGAC 
ATCGAAGTAC AGGGCTTCCG CATCCCTAAG GGAACGACAC TCATCACCAA CCTGTCATCG 
GTGCTGAAGG ATGAGGCCGT CTGGAAGAAG CCCTTCCGCT TCCACCCCGA ACACTTCCTG 
GATGCCCAGG GCCACTTTGT GAAGCCGGAG GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT 
GCATGCCTCG GGGAGCCCCT GGCCCGCATG GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG 
CAGCACTTCA GCTTCTCCGT GGCCGCCGGA CAGCCCCGGC CCAGCCACTC TCGTGTCGTC 
AGCTTTCTGG TGACCCCATC CCCCTACGAG CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001335315.1
CDS	20..1570
Translation	MGLEALVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLPHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEKAKGSPESSFNDENLRIVVGNLFLAGMVTTSTTLAWGLLLMILHLDVQRGRRVSPGCSPIVGTHVCPVRVQQEIDDVIGQVRRPEMGDQAHMPCTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR

Target ORF information:

RefSeq Version	NM_001348386.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001348386.3

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC ATGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCACCA ACGCTGGGCT GCACGCTACC CGCCAGGTCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG ATGGTGACCC GCGGCGAGGA CACGGCCGAC 
CGCCCGCCTG CGCCCATCTA CCAGGTCCTG GGCTTCGGGC CGCGTTCCCA AGGGGTGATC 
CTGTCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCGACCA AGCCGGACGC CCCTTTCGCC CCAACGGCCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTCCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CCGCACATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC ACCCCGAGAC CTGACTGAGG CCTTCCTGGC AAAGAAGGAG 
AAGGCCAAGG GGAGCCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGGT 
AACCTGTTCC TTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ACCTGGATGT GCAGCGAGGA AGGAGAGTGT CCCCTGGGTG CTCACCCATT 
GTGGGGACGC ATGTCTGTCC AGTCCGTGTC CAACAGGAGA TCGACGACGT GATAGGGCAG 
GTGCGGCGAC CAGAGATGGG TGACCAGGCT CACATGCCCT GCACCACTGC CGTGATTCAC 
GAGGTGCAGC ACTTTGGGGA CATCGTCCCC CTGGGTGTGA CCCATATGAC ATCCCGTGAC 
ATCGAAGTAC AGGGCTTCCG CATCCCTAAG GGAACGACAC TCATCACCAA CCTGTCATCG 
GTGCTGAAGG ATGAGGCCGT CTGGAAGAAG CCCTTCCGCT TCCACCCCGA ACACTTCCTG 
GATGCCCAGG GCCACTTTGT GAAGCCGGAG GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT 
GCATGCCTCG GGGAGCCCCT GGCCCGCATG GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG 
CAGCACTTCA GCTTCTCCGT GGCCGCCGGA CAGCCCCGGC CCAGCCACTC TCGTGTCGTC 
AGCTTTCTGG TGACCCCATC CCCCTACGAG CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2D7 ( NM_001348386.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001335315.1 Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu102235
Clone ID Related Accession (Same CDS sequence)	NM_001348386.2 , NM_001348386.3 , NM_001348386.1
Accession Version	NM_001348386.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	putative cytochrome P450 2D7
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC254562.1, AY220845.1, BC108679.1 and X16866.1. Transcript Variant: This variant (2) uses an alternate splice site resulting in a longer transcript compared to variant 1. This variant represents the functional allele encoding the full-length protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY220845.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 15051713 ##RefSeq-Attributes-END##

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC ATGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCACCA ACGCTGGGCT GCACGCTACC CGCCAGGTCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG ATGGTGACCC GCGGCGAGGA CACGGCCGAC 
CGCCCGCCTG CGCCCATCTA CCAGGTCCTG GGCTTCGGGC CGCGTTCCCA AGGGGTGATC 
CTGTCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCGACCA AGCCGGACGC CCCTTTCGCC CCAACGGCCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTCCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CCGCACATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC ACCCCGAGAC CTGACTGAGG CCTTCCTGGC AAAGAAGGAG 
AAGGCCAAGG GGAGCCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGGT 
AACCTGTTCC TTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ACCTGGATGT GCAGCGAGGA AGGAGAGTGT CCCCTGGGTG CTCACCCATT 
GTGGGGACGC ATGTCTGTCC AGTCCGTGTC CAACAGGAGA TCGACGACGT GATAGGGCAG 
GTGCGGCGAC CAGAGATGGG TGACCAGGCT CACATGCCCT GCACCACTGC CGTGATTCAC 
GAGGTGCAGC ACTTTGGGGA CATCGTCCCC CTGGGTGTGA CCCATATGAC ATCCCGTGAC 
ATCGAAGTAC AGGGCTTCCG CATCCCTAAG GGAACGACAC TCATCACCAA CCTGTCATCG 
GTGCTGAAGG ATGAGGCCGT CTGGAAGAAG CCCTTCCGCT TCCACCCCGA ACACTTCCTG 
GATGCCCAGG GCCACTTTGT GAAGCCGGAG GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT 
GCATGCCTCG GGGAGCCCCT GGCCCGCATG GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG 
CAGCACTTCA GCTTCTCCGT GGCCGCCGGA CAGCCCCGGC CCAGCCACTC TCGTGTCGTC 
AGCTTTCTGG TGACCCCATC CCCCTACGAG CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001335315.1
CDS	112..1662
Translation	MGLEALVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLPHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEKAKGSPESSFNDENLRIVVGNLFLAGMVTTSTTLAWGLLLMILHLDVQRGRRVSPGCSPIVGTHVCPVRVQQEIDDVIGQVRRPEMGDQAHMPCTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR

Target ORF information:

RefSeq Version	NM_001348386.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) (CYP2D7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001348386.1

ORF Insert Sequence:

ATGGGGCTAG AAGCACTGGT GCCCCTGGCC ATGATAGTGG CCATCTTCCT GCTCCTGGTG 
GACCTGATGC ACCGGCACCA ACGCTGGGCT GCACGCTACC CGCCAGGTCC CCTGCCACTG 
CCCGGGCTGG GCAACCTGCT GCATGTGGAC TTCCAGAACA CACCATACTG CTTCGACCAG 
TTGCGGCGCC GCTTCGGGGA CGTGTTCAGC CTGCAGCTGG CCTGGACGCC GGTGGTCGTG 
CTCAATGGGC TGGCGGCCGT GCGCGAGGCG ATGGTGACCC GCGGCGAGGA CACGGCCGAC 
CGCCCGCCTG CGCCCATCTA CCAGGTCCTG GGCTTCGGGC CGCGTTCCCA AGGGGTGATC 
CTGTCGCGCT ATGGGCCCGC GTGGCGCGAG CAGAGGCGCT TCTCCGTGTC CACCTTGCGC 
AACTTGGGCC TGGGCAAGAA GTCGCTGGAG CAGTGGGTGA CCGAGGAGGC CGCCTGCCTT 
TGTGCCGCCT TCGCCGACCA AGCCGGACGC CCCTTTCGCC CCAACGGCCT CTTGGACAAA 
GCCGTGAGCA ACGTGATCGC CTCCCTCACC TGCGGGCGCC GCTTCGAGTA CGACGACCCT 
CGCTTCCTCA GGCTGCTGGA CCTAGCTCAG GAGGGACTGA AGGAGGAGTC GGGCTTCCTG 
CGCGAGGTGC TGAATGCTGT CCCCGTCCTC CCGCACATCC CAGCGCTGGC TGGCAAGGTC 
CTACGCTTCC AAAAGGCTTT CCTGACCCAG CTGGATGAGC TGCTAACTGA GCACAGGATG 
ACCTGGGACC CAGCCCAGCC ACCCCGAGAC CTGACTGAGG CCTTCCTGGC AAAGAAGGAG 
AAGGCCAAGG GGAGCCCTGA GAGCAGCTTC AATGATGAGA ACCTGCGCAT AGTGGTGGGT 
AACCTGTTCC TTGCCGGGAT GGTGACCACC TCGACCACGC TGGCCTGGGG CCTCCTGCTC 
ATGATCCTAC ACCTGGATGT GCAGCGAGGA AGGAGAGTGT CCCCTGGGTG CTCACCCATT 
GTGGGGACGC ATGTCTGTCC AGTCCGTGTC CAACAGGAGA TCGACGACGT GATAGGGCAG 
GTGCGGCGAC CAGAGATGGG TGACCAGGCT CACATGCCCT GCACCACTGC CGTGATTCAC 
GAGGTGCAGC ACTTTGGGGA CATCGTCCCC CTGGGTGTGA CCCATATGAC ATCCCGTGAC 
ATCGAAGTAC AGGGCTTCCG CATCCCTAAG GGAACGACAC TCATCACCAA CCTGTCATCG 
GTGCTGAAGG ATGAGGCCGT CTGGAAGAAG CCCTTCCGCT TCCACCCCGA ACACTTCCTG 
GATGCCCAGG GCCACTTTGT GAAGCCGGAG GCCTTCCTGC CTTTCTCAGC AGGCCGCCGT 
GCATGCCTCG GGGAGCCCCT GGCCCGCATG GAGCTCTTCC TCTTCTTCAC CTCCCTGCTG 
CAGCACTTCA GCTTCTCCGT GGCCGCCGGA CAGCCCCGGC CCAGCCACTC TCGTGTCGTC 
AGCTTTCTGG TGACCCCATC CCCCTACGAG CTTTGTGCTG TGCCCCGCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.
Translational research : the journal of laboratory and clinical medicine168107-121(2016 Feb)
Wang J,Xie H,Ling Q,Lu D,Lv Z,Zhuang R,Liu Z,Wei X,Zhou L,Xu X,Zheng S

CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.
Pharmacogenomics13(1)91-111(2012 Jan)
Gaedigk A,Twist GP,Leeder JS

Expression and functional analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 isozymes.
Drug metabolism and disposition: the biological fate of chemicals37(1)1-4(2009 Jan)
Zhang WY,Tu YB,Haining RL,Yu AM

Frequency of the frame-shifting CYP2D7 138delT polymorphism in a large, ethnically diverse sample population.
Drug metabolism and disposition: the biological fate of chemicals35(8)1251-3(2007 Aug)
Bhathena A,Mueller T,Grimm DR,Idler K,Tsurutani A,Spear BB,Katz DA

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CYP2D7 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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