CST9L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CST9L
Entrez Gene ID	128821
Full Name	cystatin 9 like
Synonyms	CTES7B,bA218C14.1
General protein information	Preferred Names cystatin 9 like Names cystatin-9-like testatin testicular tissue protein Li 45
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p11.21
Summary	The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to mouse cystatin 9. Based on its testis-specific expression, it is likely to have a role in tissue reorganization during early testis development. [provided by RefSeq, Jul 2008].
Disorder MIM:	616536

mRNA and Protein(s)

mRNA	Protein	Name
NM_080610.2	NP_542177.1	cystatin-9-like precursor
NM_080610.3	NP_542177.1	cystatin-9-like precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CST9L	NP_542177.1
Bos taurus (cattle)	CST9	XP_005228604.1
Pan troglodytes (chimpanzee)	LOC740314	XP_003953738.1
	LOC713067	XP_001102265.2
Canis lupus familiaris (dog)	CST9	XP_005634221.1
Rattus norvegicus (Norway rat)	Cst9l	NP_001102067.1
Bos taurus (cattle)	LOC505033	NP_001039372.1
Mus musculus (house mouse)	Cst9	NP_034109.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution and human tissue expression of the Cres/Testatin subgroup genes, a reproductive tissue specific subgroup of the type 2 cystatins.
Frygelius J, Arvestad L, Wedell A, T?h?nen V
Evolution & development12(3)329-42(2010 May-Jun)

A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study.
Hwang SJ, Yang Q, Meigs JB, Pearce EN, Fox CS
BMC medical genetics8 Suppl 1S10(2007 Sep)

A new subgroup of the family 2 cystatins.
Cornwall GA, Hsia N
Molecular and cellular endocrinology200(1-2)1-8(2003 Feb)

Isolation of the human testatin gene and analysis in patients with abnormal gonadal development.
Eriksson A, T?h?nen V, Wedell A, Nordqvist K
Molecular human reproduction8(1)8-15(2002 Jan)

Friends and relations of the cystatin superfamily--new members and their evolution.
Brown WM, Dziegielewska KM
Protein science : a publication of the Protein Society6(1)5-12(1997 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We show with phylogenetic relations that the CTES genes are clustered into three original groups, a testatin, a Cres, and a CstL1 group
Title: Evolution and human tissue expression of the Cres/Testatin subgroup genes, a reproductive tissue specific subgroup of the type 2 cystatins.

Results describe the sequence, genomic structure, chromosomal location, and expression pattern of the human testatin gene.
Title: Isolation of the human testatin gene and analysis in patients with abnormal gonadal development.

The following CST9L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CST9L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05771	NM_080610.3 Latest version!	Homo sapiens cystatin 9 like (CST9L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu05771	NM_080610.2	Homo sapiens cystatin 9 like (CST9L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CST9L ( NM_080610.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_542177.1 Homo sapiens cystatin 9 like (CST9L), mRNA.

Price & Availability↑

CloneID	OHu05771
Clone ID Related Accession (Same CDS sequence)	NM_080610.2 , NM_080610.3
Accession Version	NM_080610.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	cystatin-9-like precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC029656.1. On Mar 12, 2008 this sequence version replaced NM_080610.1. ##Evidence-Data-START## Transcript exon combination :: BC029656.1, HM005358.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2158188, SAMEA2161674 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGGGCC TGCCGTGGAA GGGAGGTCTG TCCTGGGCGC TGCTGCTGCT TCTCTTAGGC 
TCCCAGATCC TGCTGATCTA TGCCTGGCAT TTCCACGAGC AAAGGGACTG TGATGAACAC 
AATGTCATGG CTCGTTACCT CCCTGCCACA GTGGAGTTTG CTGTCCACAC ATTCAACCAA 
CAGAGCAAGG ACTACTATGC CTACAGACTG GGGCACATCT TGAATTCCTG GAAGGAGCAG 
GTGGAGTCCA AGACTGTATT CTCAATGGAG CTACTGCTGG GGAGAACTAG GTGTGGGAAA 
TTTGAAGACG ACATTGACAA CTGCCATTTC CAAGAAAGCA CAGAGCTGAA CAATACTTTC 
ACCTGCTTCT TCACCATCAG CACCAGGCCC TGGATGACTC AGTTCAGCCT CCTGAACAAG 
ACCTGCTTGG AGGGATTCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542177.1
CDS	300..743
Translation	MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTFTCFFTISTRPWMTQFSLLNKTCLEGFH

Target ORF information:

RefSeq Version	NM_080610.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cystatin 9 like (CST9L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080610.2

ORF Insert Sequence:

ATGCTGGGCC TGCCGTGGAA GGGAGGTCTG TCCTGGGCGC TGCTGCTGCT TCTCTTAGGC 
TCCCAGATCC TGCTGATCTA TGCCTGGCAT TTCCACGAGC AAAGGGACTG TGATGAACAC 
AATGTCATGG CTCGTTACCT CCCTGCCACA GTGGAGTTTG CTGTCCACAC ATTCAACCAA 
CAGAGCAAGG ACTACTATGC CTACAGACTG GGGCACATCT TGAATTCCTG GAAGGAGCAG 
GTGGAGTCCA AGACTGTATT CTCAATGGAG CTACTGCTGG GGAGAACTAG GTGTGGGAAA 
TTTGAAGACG ACATTGACAA CTGCCATTTC CAAGAAAGCA CAGAGCTGAA CAATACTTTC 
ACCTGCTTCT TCACCATCAG CACCAGGCCC TGGATGACTC AGTTCAGCCT CCTGAACAAG 
ACCTGCTTGG AGGGATTCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CST9L ( NM_080610.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_542177.1 Homo sapiens cystatin 9 like (CST9L), mRNA.

Price & Availability↑

CloneID	OHu05771
Clone ID Related Accession (Same CDS sequence)	NM_080610.2 , NM_080610.3
Accession Version	NM_080610.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	cystatin-9-like precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC029656.1. On Nov 23, 2018 this sequence version replaced NM_080610.2. ##Evidence-Data-START## Transcript exon combination :: BC029656.1, AY358615.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2158188, SAMEA2161674 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000376979.4/ ENSP00000366178.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGGGCC TGCCGTGGAA GGGAGGTCTG TCCTGGGCGC TGCTGCTGCT TCTCTTAGGC 
TCCCAGATCC TGCTGATCTA TGCCTGGCAT TTCCACGAGC AAAGGGACTG TGATGAACAC 
AATGTCATGG CTCGTTACCT CCCTGCCACA GTGGAGTTTG CTGTCCACAC ATTCAACCAA 
CAGAGCAAGG ACTACTATGC CTACAGACTG GGGCACATCT TGAATTCCTG GAAGGAGCAG 
GTGGAGTCCA AGACTGTATT CTCAATGGAG CTACTGCTGG GGAGAACTAG GTGTGGGAAA 
TTTGAAGACG ACATTGACAA CTGCCATTTC CAAGAAAGCA CAGAGCTGAA CAATACTTTC 
ACCTGCTTCT TCACCATCAG CACCAGGCCC TGGATGACTC AGTTCAGCCT CCTGAACAAG 
ACCTGCTTGG AGGGATTCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_542177.1
CDS	35..478
Translation	MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMARYLPATVEFAVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNNTFTCFFTISTRPWMTQFSLLNKTCLEGFH

Target ORF information:

RefSeq Version	NM_080610.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cystatin 9 like (CST9L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080610.3

ORF Insert Sequence:

ATGCTGGGCC TGCCGTGGAA GGGAGGTCTG TCCTGGGCGC TGCTGCTGCT TCTCTTAGGC 
TCCCAGATCC TGCTGATCTA TGCCTGGCAT TTCCACGAGC AAAGGGACTG TGATGAACAC 
AATGTCATGG CTCGTTACCT CCCTGCCACA GTGGAGTTTG CTGTCCACAC ATTCAACCAA 
CAGAGCAAGG ACTACTATGC CTACAGACTG GGGCACATCT TGAATTCCTG GAAGGAGCAG 
GTGGAGTCCA AGACTGTATT CTCAATGGAG CTACTGCTGG GGAGAACTAG GTGTGGGAAA 
TTTGAAGACG ACATTGACAA CTGCCATTTC CAAGAAAGCA CAGAGCTGAA CAATACTTTC 
ACCTGCTTCT TCACCATCAG CACCAGGCCC TGGATGACTC AGTTCAGCCT CCTGAACAAG 
ACCTGCTTGG AGGGATTCCA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution and human tissue expression of the Cres/Testatin subgroup genes, a reproductive tissue specific subgroup of the type 2 cystatins.
Evolution & development12(3)329-42(2010 May-Jun)
Frygelius J,Arvestad L,Wedell A,T?h?nen V

A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study.
BMC medical genetics8 Suppl 1S10(2007 Sep)
Hwang SJ,Yang Q,Meigs JB,Pearce EN,Fox CS

A new subgroup of the family 2 cystatins.
Molecular and cellular endocrinology200(1-2)1-8(2003 Feb)
Cornwall GA,Hsia N

Isolation of the human testatin gene and analysis in patients with abnormal gonadal development.
Molecular human reproduction8(1)8-15(2002 Jan)
Eriksson A,T?h?nen V,Wedell A,Nordqvist K

Friends and relations of the cystatin superfamily--new members and their evolution.
Protein science : a publication of the Protein Society6(1)5-12(1997 Jan)
Brown WM,Dziegielewska KM

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CST9L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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