ADCY8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADCY8
Entrez Gene ID	114
Full Name	adenylate cyclase 8
Synonyms	AC8,ADCY3,HBAC1
General protein information	Preferred Names adenylate cyclase 8 Names adenylate cyclase type 8 ATP pyrophosphate-lyase 8 HEL-S-172mP adenylate cyclase 8 (brain) adenylate cyclase type VIII adenylyl cyclase 8 adenylyl cyclase-8, brain ca(2+)/calmodulin-activated adenylyl cyclase epididymis secretory sperm binding protein Li 172mP
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q24.22
Summary	Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008].
Disorder MIM:	103070

mRNA and Protein(s)

mRNA	Protein	Name
XM_006716501.3	XP_006716564.1	adenylate cyclase type 8 isoform X2
XM_005250769.3	XP_005250826.1	adenylate cyclase type 8 isoform X1
XM_017013006.1	XP_016868495.1	adenylate cyclase type 8 isoform X3
XM_017013007.1	XP_016868496.1	adenylate cyclase type 8 isoform X4
NM_001115.2	NP_001106.1	adenylate cyclase type 8
NM_001115.3	NP_001106.1	adenylate cyclase type 8

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	ADCY8	XP_418437.2
Xenopus tropicalis (tropical clawed frog)	adcy8	NP_001096207.1
Bos taurus (cattle)	ADCY8	NP_001179770.1
Drosophila melanogaster (fruit fly)	Ac78C	NP_001262137.1
Homo sapiens (human)	ADCY8	NP_001106.1
	ADCY8	XP_001084919.1
Rattus norvegicus (Norway rat)	Adcy8	NP_058838.1
Pan troglodytes (chimpanzee)	ADCY8	XP_519960.2
Canis lupus familiaris (dog)	ADCY8	XP_539166.2
Danio rerio (zebrafish)	adcy8	NP_001137224.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002262	XP_307919.5
Mus musculus (house mouse)	Adcy8	NP_033753.2

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.
Sung YJ, P?russe L, Sarzynski MA, Fornage M, Sidney S, Sternfeld B, Rice T, Terry JG, Jacobs DR Jr, Katzmarzyk P, Curran JE, Jeffrey Carr J, Blangero J, Ghosh S, Despr?s JP, Rankinen T, Rao DC, Bouchard C
International journal of obesity (2005)40(4)662-74(2016 Apr)

Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology.
Shen-Gunther J, Wang CM, Poage GM, Lin CL, Perez L, Banks NA, Huang TH
Clinical epigenetics896(2016)

Multilevel control of glucose homeostasis by adenylyl cyclase 8.
Raoux M, Vacher P, Papin J, Picard A, Kostrzewa E, Devin A, Gaitan J, Limon I, Kas MJ, Magnan C, Lang J
Diabetologia58(4)749-57(2015 Apr)

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
Cobb J, Cule E, Moncrieffe H, Hinks A, Ursu S, Patrick F, Kassoumeri L, Flynn E, Bulatovi? M, Wulffraat N, van Zelst B, de Jonge R, Bohm M, Dolezalova P, Hirani S, Newman S, Whitworth P, Southwood TR, De Iorio M, , , , Wedderburn LR, Thomson W
The pharmacogenomics journal14(4)356-64(2014 Aug)

A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample.
Wolf EJ, Rasmusson AM, Mitchell KS, Logue MW, Baldwin CT, Miller MW
Depression and anxiety31(4)352-60(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results provide evidence for new loci influencing abdominal visceral (BBS9, ADCY8, KCNK9) and subcutaneous (MLLT10/DNAJC1/EBLN1) fat, and confirmed a locus (THNSL2) previously reported to be associated with abdominal fat in women
Title: Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.

Results show that promoter hypermethylation of ADCY8, CDH8, and ZNF582 are correlated with high-grade squamous intraepithelial lesion.
Title: Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology.

ADCY8 is required for the physiological activation of glucose-induced signalling pathways in beta cells, for glucose tolerance and for hypothalamic adaptation to a high-fat diet via regulation of islet insulin secretion.
Title: Multilevel control of glucose homeostasis by adenylyl cyclase 8.

ADCY8 is integral for long-term potentiation and synaptic plasticity and is implicated in fear-related learning and memory.
Title: A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample.

Polymorphisms ADCY8 are associated with an alcohol-dependent phenotype in females, which is distinguished by comorbid signs of depression.
Title: Genetic markers of comorbid depression and alcoholism in women.

The following ADCY8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADCY8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31324	NM_001115.3 Latest version!	Homo sapiens adenylate cyclase 8 (ADCY8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$459.50-$643.30 $919.00
OHu97721	XM_017013007.1 Latest version!	Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu97720	XM_017013006.1 Latest version!	Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu42338	XM_005250769.3 Latest version!	Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
OHu42339	XM_006716501.3 Latest version!	Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
View Old Accession Versions >>
OHu31324	NM_001115.2	Homo sapiens adenylate cyclase 8 (ADCY8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$459.50-$643.30 $919.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADCY8 ( NM_001115.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001106.1 Homo sapiens adenylate cyclase 8 (ADCY8), mRNA.

Price & Availability↑

CloneID	OHu31324
Clone ID Related Accession (Same CDS sequence)	NM_001115.2 , NM_001115.3
Accession Version	NM_001115.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3756bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	adenylate cyclase type 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR003657.1, Z35309.1, DQ104739.1 and AC103726.5. On Feb 22, 2008 this sequence version replaced NM_001115.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GQ472223.1, Z35309.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TACTCTGGCT 
GCCCTAACAA GAAATTCAAT AAATCTGCTT CCAAACCATC TTGCACAAGC TTTGCATGTC 
CAGTCTGGGC CTGAGGAAAT TAACAAGAGA ATAGAACATA CCATCGACTT GCGGAGTGGC 
GATAAATTGA GAAGAGAGCA TATCAAGCCA TTCTCACTGA TGTTTAAAGA CTCCAGCCTG 
GAGCACAAGT ATTCTCAAAT GAGGGATGAA GTGTTCAAGT CAAACTTGGT CTGTGCATTT 
ATCGTTCTTC TATTTATCAC GGCAATACAA AGTTTGCTTC CTTCTTCAAG AGTGATGCCA 
ATGACCATCC AGTTCTCCAT TCTGATTATG CTGCACTCGG CTCTGGTCCT CATCACCACA 
GCAGAGGATT ATAAATGTTT GCCCCTCATC CTCCGGAAAA CTTGCTGTTG GATTAATGAG 
ACCTATTTGG CCCGGAACGT CATCATCTTT GCATCCATTT TGATTAATTT CCTGGGTGCC 
ATCTTAAATA TCCTGTGGTG TGATTTTGAC AAGTCGATAC CCTTGAAGAA CCTGACTTTC 
AATTCCTCAG CTGTGTTTAC AGATATCTGC TCCTACCCAG AGTACTTTGT CTTCACGGGG 
GTGTTGGCCA TGGTGACCTG TGCAGTTTTC CTCCGGCTGA ACTCCGTCCT GAAGCTGGCA 
GTGCTGCTGA TCATGATTGC CATCTATGCC CTGCTCACTG AGACCGTCTA CGCAGGCCTC 
TTTCTGCGTT ATGACAACCT CAACCACAGT GGAGAAGATT TCCTGGGGAC CAAGGAGGTA 
TCACTGCTAC TGATGGCCAT GTTCCTCCTG GCTGTGTTCT ACCATGGACA GCAGCTGGAG 
TACACAGCCC GCCTGGACTT CCTTTGGCGA GTACAGGCCA AAGAGGAGAT CAATGAGATG 
AAGGAGCTGA GGGAACACAA TGAGAACATG CTCCGGAATA TCTTACCCAG CCATGTGGCC 
CGCCATTTCC TAGAGAAGGA CCGAGACAAT GAGGAGCTGT ATTCTCAATC CTATGATGCT 
GTTGGGGTGA TGTTTGCCTC CATCCCAGGA TTTGCGGACT TTTACTCTCA GACTGAAATG 
AATAACCAGG GAGTGGAATG CCTGCGCTTG CTCAATGAGA TCATTGCTGA CTTCGATGAG 
TTGCTTGGTG AAGACCGATT TCAAGACATT GAAAAGATTA AGACCATTGG CAGCACCTAC 
ATGGCCGTGT CAGGCCTGTC ACCTGAAAAA CAGCAATGTG AAGACAAGTG GGGACATTTG 
TGTGCTCTGG CTGACTTCTC ACTCGCCCTG ACAGAAAGCA TACAGGAGAT CAACAAGCAT 
TCATTCAACA ATTTTGAACT CCGGATTGGC ATCAGCCACG GCTCAGTGGT AGCTGGCGTT 
ATCGGCGCTA AGAAACCACA GTATGACATT TGGGGCAAAA CTGTGAACCT GGCAAGCCGA 
ATGGACAGCA CGGGGGTTAG TGGCCGGATC CAAGTCCCAG AGGAGACCTA TCTCATCCTG 
AAGGACCAGG GCTTTGCCTT TGATTACCGA GGGGAGATCT ATGTGAAGGG TATCAGTGAA 
CAGGAAGGAA AAATCAAAAC GTACTTTCTT CTGGGAAGAG TCCAACCCAA CCCATTCATC 
TTGCCCCCAA GAAGACTGCC TGGGCAGTAC TCCCTGGCCG CGGTTGTCCT GGGACTTGTC 
CAGTCCCTCA ATAGGCAAAG GCAGAAGCAG CTACTCAATG AGAACAACAA CACAGGAATC 
ATCAAGGGTC ATTACAACCG GCGGACTTTG TTGTCACCCA GCGGCACAGA GCCTGGAGCC 
CAGGCTGAAG GCACCGACAA ATCTGATTTG CCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106.1
CDS	257..4012
Translation	MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGSGSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP

Target ORF information:

RefSeq Version	NM_001115.2
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 8 (ADCY8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001115.2

ORF Insert Sequence:

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TACTCTGGCT 
GCCCTAACAA GAAATTCAAT AAATCTGCTT CCAAACCATC TTGCACAAGC TTTGCATGTC 
CAGTCTGGGC CTGAGGAAAT TAACAAGAGA ATAGAACATA CCATCGACTT GCGGAGTGGC 
GATAAATTGA GAAGAGAGCA TATCAAGCCA TTCTCACTGA TGTTTAAAGA CTCCAGCCTG 
GAGCACAAGT ATTCTCAAAT GAGGGATGAA GTGTTCAAGT CAAACTTGGT CTGTGCATTT 
ATCGTTCTTC TATTTATCAC GGCAATACAA AGTTTGCTTC CTTCTTCAAG AGTGATGCCA 
ATGACCATCC AGTTCTCCAT TCTGATTATG CTGCACTCGG CTCTGGTCCT CATCACCACA 
GCAGAGGATT ATAAATGTTT GCCCCTCATC CTCCGGAAAA CTTGCTGTTG GATTAATGAG 
ACCTATTTGG CCCGGAACGT CATCATCTTT GCATCCATTT TGATTAATTT CCTGGGTGCC 
ATCTTAAATA TCCTGTGGTG TGATTTTGAC AAGTCGATAC CCTTGAAGAA CCTGACTTTC 
AATTCCTCAG CTGTGTTTAC AGATATCTGC TCCTACCCAG AGTACTTTGT CTTCACGGGG 
GTGTTGGCCA TGGTGACCTG TGCAGTTTTC CTCCGGCTGA ACTCCGTCCT GAAGCTGGCA 
GTGCTGCTGA TCATGATTGC CATCTATGCC CTGCTCACTG AGACCGTCTA CGCAGGCCTC 
TTTCTGCGTT ATGACAACCT CAACCACAGT GGAGAAGATT TCCTGGGGAC CAAGGAGGTA 
TCACTGCTAC TGATGGCCAT GTTCCTCCTG GCTGTGTTCT ACCATGGACA GCAGCTGGAG 
TACACAGCCC GCCTGGACTT CCTTTGGCGA GTACAGGCCA AAGAGGAGAT CAATGAGATG 
AAGGAGCTGA GGGAACACAA TGAGAACATG CTCCGGAATA TCTTACCCAG CCATGTGGCC 
CGCCATTTCC TAGAGAAGGA CCGAGACAAT GAGGAGCTGT ATTCTCAATC CTATGATGCT 
GTTGGGGTGA TGTTTGCCTC CATCCCAGGA TTTGCGGACT TTTACTCTCA GACTGAAATG 
AATAACCAGG GAGTGGAATG CCTGCGCTTG CTCAATGAGA TCATTGCTGA CTTCGATGAG 
TTGCTTGGTG AAGACCGATT TCAAGACATT GAAAAGATTA AGACCATTGG CAGCACCTAC 
ATGGCCGTGT CAGGCCTGTC ACCTGAAAAA CAGCAATGTG AAGACAAGTG GGGACATTTG 
TGTGCTCTGG CTGACTTCTC ACTCGCCCTG ACAGAAAGCA TACAGGAGAT CAACAAGCAT 
TCATTCAACA ATTTTGAACT CCGGATTGGC ATCAGCCACG GCTCAGTGGT AGCTGGCGTT 
ATCGGCGCTA AGAAACCACA GTATGACATT TGGGGCAAAA CTGTGAACCT GGCAAGCCGA 
ATGGACAGCA CGGGGGTTAG TGGCCGGATC CAAGTCCCAG AGGAGACCTA TCTCATCCTG 
AAGGACCAGG GCTTTGCCTT TGATTACCGA GGGGAGATCT ATGTGAAGGG TATCAGTGAA 
CAGGAAGGAA AAATCAAAAC GTACTTTCTT CTGGGAAGAG TCCAACCCAA CCCATTCATC 
TTGCCCCCAA GAAGACTGCC TGGGCAGTAC TCCCTGGCCG CGGTTGTCCT GGGACTTGTC 
CAGTCCCTCA ATAGGCAAAG GCAGAAGCAG CTACTCAATG AGAACAACAA CACAGGAATC 
ATCAAGGGTC ATTACAACCG GCGGACTTTG TTGTCACCCA GCGGCACAGA GCCTGGAGCC 
CAGGCTGAAG GCACCGACAA ATCTGATTTG CCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY8 ( NM_001115.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001106.1 Homo sapiens adenylate cyclase 8 (ADCY8), mRNA.

Price & Availability↑

CloneID	OHu31324
Clone ID Related Accession (Same CDS sequence)	NM_001115.2 , NM_001115.3
Accession Version	NM_001115.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3756bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	adenylate cyclase type 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC087341.4, DR003657.1, Z35309.1, DQ104739.1 and AC103726.5. On Nov 22, 2018 this sequence version replaced NM_001115.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GQ472223.1, Z35309.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000286355.10/ ENSP00000286355.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TACTCTGGCT 
GCCCTAACAA GAAATTCAAT AAATCTGCTT CCAAACCATC TTGCACAAGC TTTGCATGTC 
CAGTCTGGGC CTGAGGAAAT TAACAAGAGA ATAGAACATA CCATCGACTT GCGGAGTGGC 
GATAAATTGA GAAGAGAGCA TATCAAGCCA TTCTCACTGA TGTTTAAAGA CTCCAGCCTG 
GAGCACAAGT ATTCTCAAAT GAGGGATGAA GTGTTCAAGT CAAACTTGGT CTGTGCATTT 
ATCGTTCTTC TATTTATCAC GGCAATACAA AGTTTGCTTC CTTCTTCAAG AGTGATGCCA 
ATGACCATCC AGTTCTCCAT TCTGATTATG CTGCACTCGG CTCTGGTCCT CATCACCACA 
GCAGAGGATT ATAAATGTTT GCCCCTCATC CTCCGGAAAA CTTGCTGTTG GATTAATGAG 
ACCTATTTGG CCCGGAACGT CATCATCTTT GCATCCATTT TGATTAATTT CCTGGGTGCC 
ATCTTAAATA TCCTGTGGTG TGATTTTGAC AAGTCGATAC CCTTGAAGAA CCTGACTTTC 
AATTCCTCAG CTGTGTTTAC AGATATCTGC TCCTACCCAG AGTACTTTGT CTTCACGGGG 
GTGTTGGCCA TGGTGACCTG TGCAGTTTTC CTCCGGCTGA ACTCCGTCCT GAAGCTGGCA 
GTGCTGCTGA TCATGATTGC CATCTATGCC CTGCTCACTG AGACCGTCTA CGCAGGCCTC 
TTTCTGCGTT ATGACAACCT CAACCACAGT GGAGAAGATT TCCTGGGGAC CAAGGAGGTA 
TCACTGCTAC TGATGGCCAT GTTCCTCCTG GCTGTGTTCT ACCATGGACA GCAGCTGGAG 
TACACAGCCC GCCTGGACTT CCTTTGGCGA GTACAGGCCA AAGAGGAGAT CAATGAGATG 
AAGGAGCTGA GGGAACACAA TGAGAACATG CTCCGGAATA TCTTACCCAG CCATGTGGCC 
CGCCATTTCC TAGAGAAGGA CCGAGACAAT GAGGAGCTGT ATTCTCAATC CTATGATGCT 
GTTGGGGTGA TGTTTGCCTC CATCCCAGGA TTTGCGGACT TTTACTCTCA GACTGAAATG 
AATAACCAGG GAGTGGAATG CCTGCGCTTG CTCAATGAGA TCATTGCTGA CTTCGATGAG 
TTGCTTGGTG AAGACCGATT TCAAGACATT GAAAAGATTA AGACCATTGG CAGCACCTAC 
ATGGCCGTGT CAGGCCTGTC ACCTGAAAAA CAGCAATGTG AAGACAAGTG GGGACATTTG 
TGTGCTCTGG CTGACTTCTC ACTCGCCCTG ACAGAAAGCA TACAGGAGAT CAACAAGCAT 
TCATTCAACA ATTTTGAACT CCGGATTGGC ATCAGCCACG GCTCAGTGGT AGCTGGCGTT 
ATCGGCGCTA AGAAACCACA GTATGACATT TGGGGCAAAA CTGTGAACCT GGCAAGCCGA 
ATGGACAGCA CGGGGGTTAG TGGCCGGATC CAAGTCCCAG AGGAGACCTA TCTCATCCTG 
AAGGACCAGG GCTTTGCCTT TGATTACCGA GGGGAGATCT ATGTGAAGGG TATCAGTGAA 
CAGGAAGGAA AAATCAAAAC GTACTTTCTT CTGGGAAGAG TCCAACCCAA CCCATTCATC 
TTGCCCCCAA GAAGACTGCC TGGGCAGTAC TCCCTGGCCG CGGTTGTCCT GGGACTTGTC 
CAGTCCCTCA ATAGGCAAAG GCAGAAGCAG CTACTCAATG AGAACAACAA CACAGGAATC 
ATCAAGGGTC ATTACAACCG GCGGACTTTG TTGTCACCCA GCGGCACAGA GCCTGGAGCC 
CAGGCTGAAG GCACCGACAA ATCTGATTTG CCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001106.1
CDS	577..4332
Translation	MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGSGSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP

Target ORF information:

RefSeq Version	NM_001115.3
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 8 (ADCY8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001115.3

ORF Insert Sequence:

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TACTCTGGCT 
GCCCTAACAA GAAATTCAAT AAATCTGCTT CCAAACCATC TTGCACAAGC TTTGCATGTC 
CAGTCTGGGC CTGAGGAAAT TAACAAGAGA ATAGAACATA CCATCGACTT GCGGAGTGGC 
GATAAATTGA GAAGAGAGCA TATCAAGCCA TTCTCACTGA TGTTTAAAGA CTCCAGCCTG 
GAGCACAAGT ATTCTCAAAT GAGGGATGAA GTGTTCAAGT CAAACTTGGT CTGTGCATTT 
ATCGTTCTTC TATTTATCAC GGCAATACAA AGTTTGCTTC CTTCTTCAAG AGTGATGCCA 
ATGACCATCC AGTTCTCCAT TCTGATTATG CTGCACTCGG CTCTGGTCCT CATCACCACA 
GCAGAGGATT ATAAATGTTT GCCCCTCATC CTCCGGAAAA CTTGCTGTTG GATTAATGAG 
ACCTATTTGG CCCGGAACGT CATCATCTTT GCATCCATTT TGATTAATTT CCTGGGTGCC 
ATCTTAAATA TCCTGTGGTG TGATTTTGAC AAGTCGATAC CCTTGAAGAA CCTGACTTTC 
AATTCCTCAG CTGTGTTTAC AGATATCTGC TCCTACCCAG AGTACTTTGT CTTCACGGGG 
GTGTTGGCCA TGGTGACCTG TGCAGTTTTC CTCCGGCTGA ACTCCGTCCT GAAGCTGGCA 
GTGCTGCTGA TCATGATTGC CATCTATGCC CTGCTCACTG AGACCGTCTA CGCAGGCCTC 
TTTCTGCGTT ATGACAACCT CAACCACAGT GGAGAAGATT TCCTGGGGAC CAAGGAGGTA 
TCACTGCTAC TGATGGCCAT GTTCCTCCTG GCTGTGTTCT ACCATGGACA GCAGCTGGAG 
TACACAGCCC GCCTGGACTT CCTTTGGCGA GTACAGGCCA AAGAGGAGAT CAATGAGATG 
AAGGAGCTGA GGGAACACAA TGAGAACATG CTCCGGAATA TCTTACCCAG CCATGTGGCC 
CGCCATTTCC TAGAGAAGGA CCGAGACAAT GAGGAGCTGT ATTCTCAATC CTATGATGCT 
GTTGGGGTGA TGTTTGCCTC CATCCCAGGA TTTGCGGACT TTTACTCTCA GACTGAAATG 
AATAACCAGG GAGTGGAATG CCTGCGCTTG CTCAATGAGA TCATTGCTGA CTTCGATGAG 
TTGCTTGGTG AAGACCGATT TCAAGACATT GAAAAGATTA AGACCATTGG CAGCACCTAC 
ATGGCCGTGT CAGGCCTGTC ACCTGAAAAA CAGCAATGTG AAGACAAGTG GGGACATTTG 
TGTGCTCTGG CTGACTTCTC ACTCGCCCTG ACAGAAAGCA TACAGGAGAT CAACAAGCAT 
TCATTCAACA ATTTTGAACT CCGGATTGGC ATCAGCCACG GCTCAGTGGT AGCTGGCGTT 
ATCGGCGCTA AGAAACCACA GTATGACATT TGGGGCAAAA CTGTGAACCT GGCAAGCCGA 
ATGGACAGCA CGGGGGTTAG TGGCCGGATC CAAGTCCCAG AGGAGACCTA TCTCATCCTG 
AAGGACCAGG GCTTTGCCTT TGATTACCGA GGGGAGATCT ATGTGAAGGG TATCAGTGAA 
CAGGAAGGAA AAATCAAAAC GTACTTTCTT CTGGGAAGAG TCCAACCCAA CCCATTCATC 
TTGCCCCCAA GAAGACTGCC TGGGCAGTAC TCCCTGGCCG CGGTTGTCCT GGGACTTGTC 
CAGTCCCTCA ATAGGCAAAG GCAGAAGCAG CTACTCAATG AGAACAACAA CACAGGAATC 
ATCAAGGGTC ATTACAACCG GCGGACTTTG TTGTCACCCA GCGGCACAGA GCCTGGAGCC 
CAGGCTGAAG GCACCGACAA ATCTGATTTG CCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY8 ( XM_017013007.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868496.1 Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X4, mRNA.

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CloneID	OHu97721
Clone ID Related Accession (Same CDS sequence)	XM_017013007.1
Accession Version	XM_017013007.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1941bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate cyclase type 8 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TTTTTGCCCT 
GACACAACTG GTGAAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868496.1
CDS	1272..3212
Translation	MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGSGSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNFCPDTTGEK

Target ORF information:

RefSeq Version	XM_017013007.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013007.1

ORF Insert Sequence:

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TTTTTGCCCT 
GACACAACTG GTGAAAAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY8 ( XM_017013006.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868495.1 Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X3, mRNA.

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CloneID	OHu97720
Clone ID Related Accession (Same CDS sequence)	XM_017013006.1
Accession Version	XM_017013006.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate cyclase type 8 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TTATTCTCAA 
ATGAGGGATG AAGTGTTCAA GTCAAACTTG GTCTGTGCAT TTATCGTTCT TCTATTTATC 
ACGGCAATAC AAAGTTTGCT TCCTTCTTCA AGAGTGATGC CAATGACCAT CCAGTTCTCC 
ATTCTGATTA TGCTGCACTC GGCTCTGGTC CTCATCACCA CAGCAGAGGA TTATAAATGT 
TTGCCCCTCA TCCTCCGGAA AACTTGCTGT TGGATTAATG AGACCTATTT GGCCCGGAAC 
GTCATCATCT TTGCATCCAT TTTGATTAAT TTCCTGGGTG CCATCTTAAA TATCTACTTT 
GTCTTCACGG GGGTGTTGGC CATGGTGACC TGTGCAGTTT TCCTCCGGCT GAACTCCGTC 
CTGAAGCTGG CAGTGCTGCT GATCATGATT GCCATCTATG CCCTGCTCAC TGAGACCGTC 
TACGCAGGCC TCTTTCTGCG TTATGACAAC CTCAACCACA GTGGAGAAGA TTTCCTGGGG 
ACCAAGGAGG TATCACTGCT ACTGATGGCC ATGTTCCTCC TGGCTGTGTT CTACCATGGA 
CAGCAGCTGG AGTACACAGC CCGCCTGGAC TTCCTTTGGC GAGTACAGGC CAAAGAGGAG 
ATCAATGAGA TGAAGGAGCT GAGGGAACAC AATGAGAACA TGCTCCGGAA TATCTTACCC 
AGCCATGTGG CCCGCCATTT CCTAGAGAAG GACCGAGACA ATGAGGAGCT GTATTCTCAA 
TCCTATGATG CTGTTGGGGT GATGTTTGCC TCCATCCCAG GATTTGCGGA CTTTTACTCT 
CAGACTGAAA TGAATAACCA GGGAGTGGAA TGCCTGCGCT TGCTCAATGA GATCATTGCT 
GACTTCGATG AGTTGCTTGG TGAAGACCGA TTTCAAGACA TTGAAAAGAT TAAGACCATT 
GGCAGCACCT ACATGGCCGT GTCAGGCCTG TCACCTGAAA AACAGCAATG TGAAGACAAG 
TGGGGACATT TGTGTGCTCT GGCTGACTTC TCACTCGCCC TGACAGAAAG CATACAGGAG 
ATCAACAAGC ATTCATTCAA CAATTTTGAA CTCCGGATTG GCATCAGCCA CGGCTCAGTG 
GTAGCTGGCG TTATCGGCGC TAAGAAACCA CAGTATGACA TTTGGGGCAA AACTGTGAAC 
CTGGCAAGCC GAATGGACAG CACGGGGGTT AGTGGCCGGA TCCAAGTCCC AGAGGAGACC 
TATCTCATCC TGAAGGACCA GGGCTTTGCC TTTGATTACC GAGGGGAGAT CTATGTGAAG 
GGTATCAGTG AACAGGAAGG AAAAATCAAA ACGTACTTTC TTCTGGGAAG AGTCCAACCC 
AACCCATTCA TCTTGCCCCC AAGAAGACTG CCTGGGCAGT ACTCCCTGGC CGCGGTTGTC 
CTGGGACTTG TCCAGTCCCT CAATAGGCAA AGGCAGAAGC AGCTACTCAA TGAGAACAAC 
AACACAGGAA TCATCAAGGG TCATTACAAC CGGCGGACTT TGTTGTCACC CAGCGGCACA 
GAGCCTGGAG CCCAGGCTGA AGGCACCGAC AAATCTGATT TGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868495.1
CDS	346..3813
Translation	MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGSGSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAILNIYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP

Target ORF information:

RefSeq Version	XM_017013006.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013006.1

ORF Insert Sequence:

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TTATTCTCAA 
ATGAGGGATG AAGTGTTCAA GTCAAACTTG GTCTGTGCAT TTATCGTTCT TCTATTTATC 
ACGGCAATAC AAAGTTTGCT TCCTTCTTCA AGAGTGATGC CAATGACCAT CCAGTTCTCC 
ATTCTGATTA TGCTGCACTC GGCTCTGGTC CTCATCACCA CAGCAGAGGA TTATAAATGT 
TTGCCCCTCA TCCTCCGGAA AACTTGCTGT TGGATTAATG AGACCTATTT GGCCCGGAAC 
GTCATCATCT TTGCATCCAT TTTGATTAAT TTCCTGGGTG CCATCTTAAA TATCTACTTT 
GTCTTCACGG GGGTGTTGGC CATGGTGACC TGTGCAGTTT TCCTCCGGCT GAACTCCGTC 
CTGAAGCTGG CAGTGCTGCT GATCATGATT GCCATCTATG CCCTGCTCAC TGAGACCGTC 
TACGCAGGCC TCTTTCTGCG TTATGACAAC CTCAACCACA GTGGAGAAGA TTTCCTGGGG 
ACCAAGGAGG TATCACTGCT ACTGATGGCC ATGTTCCTCC TGGCTGTGTT CTACCATGGA 
CAGCAGCTGG AGTACACAGC CCGCCTGGAC TTCCTTTGGC GAGTACAGGC CAAAGAGGAG 
ATCAATGAGA TGAAGGAGCT GAGGGAACAC AATGAGAACA TGCTCCGGAA TATCTTACCC 
AGCCATGTGG CCCGCCATTT CCTAGAGAAG GACCGAGACA ATGAGGAGCT GTATTCTCAA 
TCCTATGATG CTGTTGGGGT GATGTTTGCC TCCATCCCAG GATTTGCGGA CTTTTACTCT 
CAGACTGAAA TGAATAACCA GGGAGTGGAA TGCCTGCGCT TGCTCAATGA GATCATTGCT 
GACTTCGATG AGTTGCTTGG TGAAGACCGA TTTCAAGACA TTGAAAAGAT TAAGACCATT 
GGCAGCACCT ACATGGCCGT GTCAGGCCTG TCACCTGAAA AACAGCAATG TGAAGACAAG 
TGGGGACATT TGTGTGCTCT GGCTGACTTC TCACTCGCCC TGACAGAAAG CATACAGGAG 
ATCAACAAGC ATTCATTCAA CAATTTTGAA CTCCGGATTG GCATCAGCCA CGGCTCAGTG 
GTAGCTGGCG TTATCGGCGC TAAGAAACCA CAGTATGACA TTTGGGGCAA AACTGTGAAC 
CTGGCAAGCC GAATGGACAG CACGGGGGTT AGTGGCCGGA TCCAAGTCCC AGAGGAGACC 
TATCTCATCC TGAAGGACCA GGGCTTTGCC TTTGATTACC GAGGGGAGAT CTATGTGAAG 
GGTATCAGTG AACAGGAAGG AAAAATCAAA ACGTACTTTC TTCTGGGAAG AGTCCAACCC 
AACCCATTCA TCTTGCCCCC AAGAAGACTG CCTGGGCAGT ACTCCCTGGC CGCGGTTGTC 
CTGGGACTTG TCCAGTCCCT CAATAGGCAA AGGCAGAAGC AGCTACTCAA TGAGAACAAC 
AACACAGGAA TCATCAAGGG TCATTACAAC CGGCGGACTT TGTTGTCACC CAGCGGCACA 
GAGCCTGGAG CCCAGGCTGA AGGCACCGAC AAATCTGATT TGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY8 ( XM_005250769.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005250826.1 Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X1, mRNA.

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CloneID	OHu42338
Clone ID Related Accession (Same CDS sequence)	XM_005250769.3
Accession Version	XM_005250769.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate cyclase type 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005250769.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TACTCTGGCT 
GCCCTAACAA GAAATTCAAT AAATCTGCTT CCAAACCATC TTGCACAAGC TTTGCATGTC 
CAGTCTGGGC CTGAGGAAAT TAACAAGAGA ATAGAACATA CCATCGACTT GCGGAGTGGC 
GATAAATTGA GAAGAGAGCA TATCAAGCCA TTCTCACTGA TGTTTAAAGA CTCCAGCCTG 
GAGCACAAGT ATTCTCAAAT GAGGGATGAA GTGTTCAAGT CAAACTTGGT CTGTGCATTT 
ATCGTTCTTC TATTTATCAC GGCAATACAA AGTTTGCTTC CTTCTTCAAG AGTGATGCCA 
ATGACCATCC AGTTCTCCAT TCTGATTATG CTGCACTCGG CTCTGGTCCT CATCACCACA 
GCAGAGGATT ATAAATGTTT GCCCCTCATC CTCCGGAAAA CTTGCTGTTG GATTAATGAG 
ACCTATTTGG CCCGGAACGT CATCATCTTT GCATCCATTT TGATTAATTT CCTGGGTGCC 
ATCTTAAATA TCTACTTTGT CTTCACGGGG GTGTTGGCCA TGGTGACCTG TGCAGTTTTC 
CTCCGGCTGA ACTCCGTCCT GAAGCTGGCA GTGCTGCTGA TCATGATTGC CATCTATGCC 
CTGCTCACTG AGACCGTCTA CGCAGGCCTC TTTCTGCGTT ATGACAACCT CAACCACAGT 
GGAGAAGATT TCCTGGGGAC CAAGGAGGTA TCACTGCTAC TGATGGCCAT GTTCCTCCTG 
GCTGTGTTCT ACCATGGACA GCAGCTGGAG TACACAGCCC GCCTGGACTT CCTTTGGCGA 
GTACAGGCCA AAGAGGAGAT CAATGAGATG AAGGAGCTGA GGGAACACAA TGAGAACATG 
CTCCGGAATA TCTTACCCAG CCATGTGGCC CGCCATTTCC TAGAGAAGGA CCGAGACAAT 
GAGGAGCTGT ATTCTCAATC CTATGATGCT GTTGGGGTGA TGTTTGCCTC CATCCCAGGA 
TTTGCGGACT TTTACTCTCA GACTGAAATG AATAACCAGG GAGTGGAATG CCTGCGCTTG 
CTCAATGAGA TCATTGCTGA CTTCGATGAG TTGCTTGGTG AAGACCGATT TCAAGACATT 
GAAAAGATTA AGACCATTGG CAGCACCTAC ATGGCCGTGT CAGGCCTGTC ACCTGAAAAA 
CAGCAATGTG AAGACAAGTG GGGACATTTG TGTGCTCTGG CTGACTTCTC ACTCGCCCTG 
ACAGAAAGCA TACAGGAGAT CAACAAGCAT TCATTCAACA ATTTTGAACT CCGGATTGGC 
ATCAGCCACG GCTCAGTGGT AGCTGGCGTT ATCGGCGCTA AGAAACCACA GTATGACATT 
TGGGGCAAAA CTGTGAACCT GGCAAGCCGA ATGGACAGCA CGGGGGTTAG TGGCCGGATC 
CAAGTCCCAG AGGAGACCTA TCTCATCCTG AAGGACCAGG GCTTTGCCTT TGATTACCGA 
GGGGAGATCT ATGTGAAGGG TATCAGTGAA CAGGAAGGAA AAATCAAAAC GTACTTTCTT 
CTGGGAAGAG TCCAACCCAA CCCATTCATC TTGCCCCCAA GAAGACTGCC TGGGCAGTAC 
TCCCTGGCCG CGGTTGTCCT GGGACTTGTC CAGTCCCTCA ATAGGCAAAG GCAGAAGCAG 
CTACTCAATG AGAACAACAA CACAGGAATC ATCAAGGGTC ATTACAACCG GCGGACTTTG 
TTGTCACCCA GCGGCACAGA GCCTGGAGCC CAGGCTGAAG GCACCGACAA ATCTGATTTG 
CCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005250826.1
CDS	380..4045
Translation	MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGSGSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAILNIYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP

Target ORF information:

RefSeq Version	XM_005250769.3
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005250769.3

ORF Insert Sequence:

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TACTCTGGCT 
GCCCTAACAA GAAATTCAAT AAATCTGCTT CCAAACCATC TTGCACAAGC TTTGCATGTC 
CAGTCTGGGC CTGAGGAAAT TAACAAGAGA ATAGAACATA CCATCGACTT GCGGAGTGGC 
GATAAATTGA GAAGAGAGCA TATCAAGCCA TTCTCACTGA TGTTTAAAGA CTCCAGCCTG 
GAGCACAAGT ATTCTCAAAT GAGGGATGAA GTGTTCAAGT CAAACTTGGT CTGTGCATTT 
ATCGTTCTTC TATTTATCAC GGCAATACAA AGTTTGCTTC CTTCTTCAAG AGTGATGCCA 
ATGACCATCC AGTTCTCCAT TCTGATTATG CTGCACTCGG CTCTGGTCCT CATCACCACA 
GCAGAGGATT ATAAATGTTT GCCCCTCATC CTCCGGAAAA CTTGCTGTTG GATTAATGAG 
ACCTATTTGG CCCGGAACGT CATCATCTTT GCATCCATTT TGATTAATTT CCTGGGTGCC 
ATCTTAAATA TCTACTTTGT CTTCACGGGG GTGTTGGCCA TGGTGACCTG TGCAGTTTTC 
CTCCGGCTGA ACTCCGTCCT GAAGCTGGCA GTGCTGCTGA TCATGATTGC CATCTATGCC 
CTGCTCACTG AGACCGTCTA CGCAGGCCTC TTTCTGCGTT ATGACAACCT CAACCACAGT 
GGAGAAGATT TCCTGGGGAC CAAGGAGGTA TCACTGCTAC TGATGGCCAT GTTCCTCCTG 
GCTGTGTTCT ACCATGGACA GCAGCTGGAG TACACAGCCC GCCTGGACTT CCTTTGGCGA 
GTACAGGCCA AAGAGGAGAT CAATGAGATG AAGGAGCTGA GGGAACACAA TGAGAACATG 
CTCCGGAATA TCTTACCCAG CCATGTGGCC CGCCATTTCC TAGAGAAGGA CCGAGACAAT 
GAGGAGCTGT ATTCTCAATC CTATGATGCT GTTGGGGTGA TGTTTGCCTC CATCCCAGGA 
TTTGCGGACT TTTACTCTCA GACTGAAATG AATAACCAGG GAGTGGAATG CCTGCGCTTG 
CTCAATGAGA TCATTGCTGA CTTCGATGAG TTGCTTGGTG AAGACCGATT TCAAGACATT 
GAAAAGATTA AGACCATTGG CAGCACCTAC ATGGCCGTGT CAGGCCTGTC ACCTGAAAAA 
CAGCAATGTG AAGACAAGTG GGGACATTTG TGTGCTCTGG CTGACTTCTC ACTCGCCCTG 
ACAGAAAGCA TACAGGAGAT CAACAAGCAT TCATTCAACA ATTTTGAACT CCGGATTGGC 
ATCAGCCACG GCTCAGTGGT AGCTGGCGTT ATCGGCGCTA AGAAACCACA GTATGACATT 
TGGGGCAAAA CTGTGAACCT GGCAAGCCGA ATGGACAGCA CGGGGGTTAG TGGCCGGATC 
CAAGTCCCAG AGGAGACCTA TCTCATCCTG AAGGACCAGG GCTTTGCCTT TGATTACCGA 
GGGGAGATCT ATGTGAAGGG TATCAGTGAA CAGGAAGGAA AAATCAAAAC GTACTTTCTT 
CTGGGAAGAG TCCAACCCAA CCCATTCATC TTGCCCCCAA GAAGACTGCC TGGGCAGTAC 
TCCCTGGCCG CGGTTGTCCT GGGACTTGTC CAGTCCCTCA ATAGGCAAAG GCAGAAGCAG 
CTACTCAATG AGAACAACAA CACAGGAATC ATCAAGGGTC ATTACAACCG GCGGACTTTG 
TTGTCACCCA GCGGCACAGA GCCTGGAGCC CAGGCTGAAG GCACCGACAA ATCTGATTTG 
CCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADCY8 ( XM_006716501.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006716564.1 Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X2, mRNA.

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CloneID	OHu42339
Clone ID Related Accession (Same CDS sequence)	XM_006716501.3
Accession Version	XM_006716501.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate cyclase type 8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006716501.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TTATTCTCAA 
ATGAGGGATG AAGTGTTCAA GTCAAACTTG GTCTGTGCAT TTATCGTTCT TCTATTTATC 
ACGGCAATAC AAAGTTTGCT TCCTTCTTCA AGAGTGATGC CAATGACCAT CCAGTTCTCC 
ATTCTGATTA TGCTGCACTC GGCTCTGGTC CTCATCACCA CAGCAGAGGA TTATAAATGT 
TTGCCCCTCA TCCTCCGGAA AACTTGCTGT TGGATTAATG AGACCTATTT GGCCCGGAAC 
GTCATCATCT TTGCATCCAT TTTGATTAAT TTCCTGGGTG CCATCTTAAA TATCCTGTGG 
TGTGATTTTG ACAAGTCGAT ACCCTTGAAG AACCTGACTT TCAATTCCTC AGCTGTGTTT 
ACAGATATCT GCTCCTACCC AGAGTACTTT GTCTTCACGG GGGTGTTGGC CATGGTGACC 
TGTGCAGTTT TCCTCCGGCT GAACTCCGTC CTGAAGCTGG CAGTGCTGCT GATCATGATT 
GCCATCTATG CCCTGCTCAC TGAGACCGTC TACGCAGGCC TCTTTCTGCG TTATGACAAC 
CTCAACCACA GTGGAGAAGA TTTCCTGGGG ACCAAGGAGG TATCACTGCT ACTGATGGCC 
ATGTTCCTCC TGGCTGTGTT CTACCATGGA CAGCAGCTGG AGTACACAGC CCGCCTGGAC 
TTCCTTTGGC GAGTACAGGC CAAAGAGGAG ATCAATGAGA TGAAGGAGCT GAGGGAACAC 
AATGAGAACA TGCTCCGGAA TATCTTACCC AGCCATGTGG CCCGCCATTT CCTAGAGAAG 
GACCGAGACA ATGAGGAGCT GTATTCTCAA TCCTATGATG CTGTTGGGGT GATGTTTGCC 
TCCATCCCAG GATTTGCGGA CTTTTACTCT CAGACTGAAA TGAATAACCA GGGAGTGGAA 
TGCCTGCGCT TGCTCAATGA GATCATTGCT GACTTCGATG AGTTGCTTGG TGAAGACCGA 
TTTCAAGACA TTGAAAAGAT TAAGACCATT GGCAGCACCT ACATGGCCGT GTCAGGCCTG 
TCACCTGAAA AACAGCAATG TGAAGACAAG TGGGGACATT TGTGTGCTCT GGCTGACTTC 
TCACTCGCCC TGACAGAAAG CATACAGGAG ATCAACAAGC ATTCATTCAA CAATTTTGAA 
CTCCGGATTG GCATCAGCCA CGGCTCAGTG GTAGCTGGCG TTATCGGCGC TAAGAAACCA 
CAGTATGACA TTTGGGGCAA AACTGTGAAC CTGGCAAGCC GAATGGACAG CACGGGGGTT 
AGTGGCCGGA TCCAAGTCCC AGAGGAGACC TATCTCATCC TGAAGGACCA GGGCTTTGCC 
TTTGATTACC GAGGGGAGAT CTATGTGAAG GGTATCAGTG AACAGGAAGG AAAAATCAAA 
ACGTACTTTC TTCTGGGAAG AGTCCAACCC AACCCATTCA TCTTGCCCCC AAGAAGACTG 
CCTGGGCAGT ACTCCCTGGC CGCGGTTGTC CTGGGACTTG TCCAGTCCCT CAATAGGCAA 
AGGCAGAAGC AGCTACTCAA TGAGAACAAC AACACAGGAA TCATCAAGGG TCATTACAAC 
CGGCGGACTT TGTTGTCACC CAGCGGCACA GAGCCTGGAG CCCAGGCTGA AGGCACCGAC 
AAATCTGATT TGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006716564.1
CDS	584..4141
Translation	MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSGSGSGGSGKASDPAGGGPNHHAPQLSGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP

Target ORF information:

RefSeq Version	XM_006716501.3
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate cyclase 8 (ADCY8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006716501.3

ORF Insert Sequence:

ATGGAGCTCT CCGATGTGCG CTGCCTTACA GGCAGCGAGG AACTCTACAC CATCCACCCG 
ACGCCCCCGG CCGGCGACGG CAGGAGCGCC TCCCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGAC ACATCACGGA GCAGCGCTTC ATTCACGGGC ACCGGGGAGG CAGCGGCAGC 
GGGAGTGGAG GCTCGGGCAA AGCCTCGGAC CCTGCGGGCG GCGGCCCCAA CCACCACGCG 
CCGCAGCTGT CAGGCGACTC GGCGCTGCCC CTCTACTCGC TGGGCCCGGG AGAGCGAGCG 
CACAGCACCT GCGGCACCAA AGTCTTCCCG GAACGCAGCG GGAGCGGCAG TGCCAGCGGC 
AGCGGAGGCG GGGGCGACCT GGGCTTCCTG CACCTTGACT GTGCCCCTAG CAACTCGGAT 
TTCTTTCTTA ATGGGGGCTA TAGCTACCGA GGGGTCATTT TCCCCACCCT GCGCAACTCC 
TTCAAATCTC GGGATTTGGA ACGCCTCTAC CAGCGCTATT TCTTGGGCCA AAGGCGCAAA 
TCGGAAGTGG TGATGAACGT GCTGGACGTG CTGACCAAAC TCACTCTCTT GGTCCTACAC 
TTGAGCCTGG CCTCGGCCCC CATGGACCCG CTCAAGGGCA TCCTGCTGGG CTTCTTCACC 
GGCATTGAGG TAGTGATCTG CGCCCTGGTG GTGGTCAGGA AGGACACCAC CTCCCACACG 
TACCTGCAGT ACAGCGGCGT GGTCACCTGG GTGGCCATGA CCACCCAGAT CCTGGCAGCA 
GGCCTCGGCT ACGGGCTCCT GGGCGACGGC ATAGGCTACG TGCTCTTCAC GCTCTTCGCC 
ACCTACAGTA TGCTGCCGCT GCCGCTCACC TGGGCCATCC TGGCCGGCCT GGGCACCTCG 
CTGCTGCAGG TCATCCTCCA AGTGGTCATA CCCCGGCTGG CGGTCATTTC CATCAACCAG 
GTTGTGGCCC AGGCAGTGCT ATTCATGTGT ATGAACACAG CTGGAATCTT CATCAGTTAC 
CTGTCAGACC GGGCCCAGCG CCAAGCTTTC CTGGAGACTC GGAGGTGTGT GGAGGCCAGG 
CTGCGCCTGG AGACAGAGAA CCAAAGACAG GAGCGGCTCG TGCTTTCTGT GCTCCCCCGG 
TTTGTTGTCC TGGAAATGAT CAACGACATG ACCAATGTGG AAGATGAGCA CCTGCAGCAC 
CAGTTCCATC GGATCTACAT CCATCGCTAT GAGAACGTCA GTATTCTTTT TGCAGATGTT 
AAAGGATTTA CCAACCTCTC CACGACCTTG TCTGCTCAGG AGCTGGTCAG GATGCTCAAC 
GAGCTCTTTG CCAGATTTGA TCGACTGGCC CATGAGCATC ACTGCCTTCG TATTAAAATC 
CTGGGGGACT GCTACTACTG CGTGTCTGGA CTTCCTGAGC CCCGCCAGGA CCATGCCCAC 
TGCTGTGTTG AAATGGGTCT CAGCATGATC AAAACCATCA GGTATGTGCG GTCAAGGACA 
AAACACGATG TTGACATGAG GATTGGAATC CACTCCGGCT CGGTGCTGTG CGGTGTTTTG 
GGACTAAGGA AGTGGCAGTT TGATGTCTGG TCTTGGGATG TGGATATTGC AAACAAACTC 
GAATCTGGAG GAATCCCTGG GAGGATTCAC ATTTCCAAAG CCACGCTGGA CTGTCTCAAC 
GGTGACTATA ACGTGGAAGA GGGCCATGGT AAAGAGAGGA ATGAATTCCT GAGGAAGCAT 
AATATCGAAA CTTACTTAAT TAAGCAGCCT GAGGACAGTC TGCTGTCCTT GCCTGAAGAT 
ATCGTCAAGG AGTCAGTGAG CTCCTCAGAC CGGAGAAACA GTGGGGCCAC ATTCACTGAA 
GGATCCTGGA GCCCTGAACT GCCCTTTGAT AATATCGTGG GGAAACAGAA TTATTCTCAA 
ATGAGGGATG AAGTGTTCAA GTCAAACTTG GTCTGTGCAT TTATCGTTCT TCTATTTATC 
ACGGCAATAC AAAGTTTGCT TCCTTCTTCA AGAGTGATGC CAATGACCAT CCAGTTCTCC 
ATTCTGATTA TGCTGCACTC GGCTCTGGTC CTCATCACCA CAGCAGAGGA TTATAAATGT 
TTGCCCCTCA TCCTCCGGAA AACTTGCTGT TGGATTAATG AGACCTATTT GGCCCGGAAC 
GTCATCATCT TTGCATCCAT TTTGATTAAT TTCCTGGGTG CCATCTTAAA TATCCTGTGG 
TGTGATTTTG ACAAGTCGAT ACCCTTGAAG AACCTGACTT TCAATTCCTC AGCTGTGTTT 
ACAGATATCT GCTCCTACCC AGAGTACTTT GTCTTCACGG GGGTGTTGGC CATGGTGACC 
TGTGCAGTTT TCCTCCGGCT GAACTCCGTC CTGAAGCTGG CAGTGCTGCT GATCATGATT 
GCCATCTATG CCCTGCTCAC TGAGACCGTC TACGCAGGCC TCTTTCTGCG TTATGACAAC 
CTCAACCACA GTGGAGAAGA TTTCCTGGGG ACCAAGGAGG TATCACTGCT ACTGATGGCC 
ATGTTCCTCC TGGCTGTGTT CTACCATGGA CAGCAGCTGG AGTACACAGC CCGCCTGGAC 
TTCCTTTGGC GAGTACAGGC CAAAGAGGAG ATCAATGAGA TGAAGGAGCT GAGGGAACAC 
AATGAGAACA TGCTCCGGAA TATCTTACCC AGCCATGTGG CCCGCCATTT CCTAGAGAAG 
GACCGAGACA ATGAGGAGCT GTATTCTCAA TCCTATGATG CTGTTGGGGT GATGTTTGCC 
TCCATCCCAG GATTTGCGGA CTTTTACTCT CAGACTGAAA TGAATAACCA GGGAGTGGAA 
TGCCTGCGCT TGCTCAATGA GATCATTGCT GACTTCGATG AGTTGCTTGG TGAAGACCGA 
TTTCAAGACA TTGAAAAGAT TAAGACCATT GGCAGCACCT ACATGGCCGT GTCAGGCCTG 
TCACCTGAAA AACAGCAATG TGAAGACAAG TGGGGACATT TGTGTGCTCT GGCTGACTTC 
TCACTCGCCC TGACAGAAAG CATACAGGAG ATCAACAAGC ATTCATTCAA CAATTTTGAA 
CTCCGGATTG GCATCAGCCA CGGCTCAGTG GTAGCTGGCG TTATCGGCGC TAAGAAACCA 
CAGTATGACA TTTGGGGCAA AACTGTGAAC CTGGCAAGCC GAATGGACAG CACGGGGGTT 
AGTGGCCGGA TCCAAGTCCC AGAGGAGACC TATCTCATCC TGAAGGACCA GGGCTTTGCC 
TTTGATTACC GAGGGGAGAT CTATGTGAAG GGTATCAGTG AACAGGAAGG AAAAATCAAA 
ACGTACTTTC TTCTGGGAAG AGTCCAACCC AACCCATTCA TCTTGCCCCC AAGAAGACTG 
CCTGGGCAGT ACTCCCTGGC CGCGGTTGTC CTGGGACTTG TCCAGTCCCT CAATAGGCAA 
AGGCAGAAGC AGCTACTCAA TGAGAACAAC AACACAGGAA TCATCAAGGG TCATTACAAC 
CGGCGGACTT TGTTGTCACC CAGCGGCACA GAGCCTGGAG CCCAGGCTGA AGGCACCGAC 
AAATCTGATT TGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.
International journal of obesity (2005)40(4)662-74(2016 Apr)
Sung YJ,P?russe L,Sarzynski MA,Fornage M,Sidney S,Sternfeld B,Rice T,Terry JG,Jacobs DR Jr,Katzmarzyk P,Curran JE,Jeffrey Carr J,Blangero J,Ghosh S,Despr?s JP,Rankinen T,Rao DC,Bouchard C

Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology.
Clinical epigenetics896(2016)
Shen-Gunther J,Wang CM,Poage GM,Lin CL,Perez L,Banks NA,Huang TH

Multilevel control of glucose homeostasis by adenylyl cyclase 8.
Diabetologia58(4)749-57(2015 Apr)
Raoux M,Vacher P,Papin J,Picard A,Kostrzewa E,Devin A,Gaitan J,Limon I,Kas MJ,Magnan C,Lang J

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.
The pharmacogenomics journal14(4)356-64(2014 Aug)
Cobb J,Cule E,Moncrieffe H,Hinks A,Ursu S,Patrick F,Kassoumeri L,Flynn E,Bulatovi? M,Wulffraat N,van Zelst B,de Jonge R,Bohm M,Dolezalova P,Hirani S,Newman S,Whitworth P,Southwood TR,De Iorio M,,,,Wedderburn LR,Thomson W

A genome-wide association study of clinical symptoms of dissociation in a trauma-exposed sample.
Depression and anxiety31(4)352-60(2014 Apr)
Wolf EJ,Rasmusson AM,Mitchell KS,Logue MW,Baldwin CT,Miller MW

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ADCY8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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