Adcy8 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adcy8
Entrez Gene ID	11514
Full Name	adenylate cyclase 8
Synonyms	AC8,AW060868
General protein information	Preferred Names adenylate cyclase 8 Names adenylate cyclase type 8 ATP pyrophosphate-lyase 8 adenylate cyclase type VIII adenylyl cyclase 8 ca(2+)/calmodulin-activated adenylyl cyclase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15 D1\|15 29.03 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_001331075.1	NP_001318004.1	adenylate cyclase type 8 isoform 3
NM_001291903.1	NP_001278832.1	adenylate cyclase type 8 isoform 2
NM_009623.2	NP_033753.2	adenylate cyclase type 8 isoform 1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	ADCY8	XP_418437.2
Xenopus tropicalis (tropical clawed frog)	adcy8	NP_001096207.1
Bos taurus (cattle)	ADCY8	NP_001179770.1
Drosophila melanogaster (fruit fly)	Ac78C	NP_001262137.1
Homo sapiens (human)	ADCY8	NP_001106.1
	ADCY8	XP_001084919.1
Rattus norvegicus (Norway rat)	Adcy8	NP_058838.1
Pan troglodytes (chimpanzee)	ADCY8	XP_519960.2
Canis lupus familiaris (dog)	ADCY8	XP_539166.2
Danio rerio (zebrafish)	adcy8	NP_001137224.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002262	XP_307919.5
Mus musculus (house mouse)	Adcy8	NP_033753.2

Gene Ontology
Bibliography

Related articles in PubMed

PBX transcription factors drive pulmonary vascular adaptation to birth.
McCulley DJ, Wienhold MD, Hines EA, Hacker TA, Rogers A, Pewowaruk RJ, Zewdu R, Chesler NC, Selleri L, Sun X
The Journal of clinical investigation(2017 Dec)

Memory Retrieval Re-Activates Erk1/2 Signaling in the Same Set of CA1 Neurons Recruited During Conditioning.
Zamorano C, Fern?ndez-Albert J, Storm DR, Carn? X, Sindreu C
Neuroscience(2017 Mar)

Calcium activated adenylyl cyclase AC8 but not AC1 is required for prolonged behavioral anxiety.
Bernabucci M, Zhuo M
Molecular brain9(1)60(2016 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Genetic deletion of AC8 (adenylyl cyclase 8) but not AC1 abolished long-lasting anxiety.
Title: Calcium activated adenylyl cyclase AC8 but not AC1 is required for prolonged behavioral anxiety.

Dysregulation of a survival pathway in adenylyl cyclase 1 and 8 knockout mice was identified following early-life ethanol exposure.
Title: Dysregulation of TrkB phosphorylation and proBDNF protein in adenylyl cyclase 1 and 8 knockout mice in a model of fetal alcohol spectrum disorder.

Study shows that AC8 is involved in epileptogenesis, and may serve as a potential target for the treatment of epilepsy
Title: A reduced susceptibility to chemoconvulsant stimulation in adenylyl cyclase 8 knockout mice.

ADCY8 is required for the physiological activation of glucose-induced signalling pathways in beta cells, for glucose tolerance and for hypothalamic adaptation to a high-fat diet via regulation of islet insulin secretion.
Title: Multilevel control of glucose homeostasis by adenylyl cyclase 8.

these results support a complex role of cAMP signaling pathways confirming the involvement of AC8 in the modulation of stress responses.
Title: Functional role of Calcium-stimulated adenylyl cyclase 8 in adaptations to psychological stressors in the mouse: implications for mood disorders.

The following Adcy8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adcy8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu19966	NM_001291903.1 Latest version!	Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
OMu23616	NM_009623.2 Latest version!	Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$734.30 $1049.00
OMu50854	NM_001331075.1 Latest version!	Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adcy8 ( NM_001291903.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001278832.1 Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu19966
Clone ID Related Accession (Same CDS sequence)	NM_001291903.1
Accession Version	NM_001291903.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3660bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-26
Organism	Mus musculus(house mouse)
Product	adenylate cyclase type 8 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK138244.1 and BC094231.1. On May 8, 2014 this sequence version replaced XM_006520318.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK138244.1, SRR1660815.242913.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849377, SAMN00849378 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTCT CGGATGTGCA CTGCCTTAGT GGCAGCGAGG AACTCTACAC CATCCAACCG 
ACGCCCCCGG CCGGCGACGA CGGGAGCGGC TCTCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGGC ACATCACGGA GCAGCGCTTC ATCCACGGGC ACCGAGGCGG CGGCGGCGGC 
GGGGTCTCCC GCAAAGCCTC GAACCCTGCG GGCAGTGGAC CCAATCACCA CGCGCCGCAG 
CTGTCTAGCG ACTCGGTGCT GCCTCTCTAT TCTCTGGGCC CCGGAGAGCG AGCGCACAAC 
ACCGGTGGCA CCAAAGTCTT TCCGGAACGC AGCGGGAGCG GCAGTGCCAG TGGCAGCGGG 
GGCGGGGGCG ACTTGGGCTT CCTACACCTT GACTGTGCCC CAAGTAACTC GGATTTCTTC 
CTCAATGGAG GATACAGCTA CCGAGGGGTC ATTTTTCCAA CCCTACGCAA CTCCTTCAAG 
TCTCGGGATC TGGAGCGCCT CTACCAACGC TATTTCCTGG GCCAGAGGCG CAAATCGGAG 
GTAGTGATGA ACGTGTTGGA TGTACTAACC AAACTCACCC TTTTAGTCCT GCACTTGAGC 
CTGGCCTCGG CTCCAATGGA CCCTCTCAAG GGCATCCTGC TAGGCTTTTT CACTGGCATC 
GAGGTGGTGA TCTGCGCCCT CGTGGTGGTC AGGAAGGACA ACACCTCCCA CACTTACCTG 
CAATACAGCG GCGTGGTCAC TTGGGTGGCT ATGACCACCC AGATTCTGGC AGCAGGCCTG 
GGCTATGGGC TTCTGGGCGA CGGCATAGGC TACGTGCTTT TTACACTCTT CGCCACCTAC 
AGCATGCTTC CCCTGCCTCT CACCTGGGCC ATCTTGGCCG GCCTGGGCAC ATCTTTGCTG 
CAAGTCACCC TTCAAGTACT CATACCCAGG CTAGCGGTCT TTTCCATCAA CCAGGTCCTG 
GCCCAGGTGG TGCTATTCAT GTGTATGAAT ACAGCAGGAA TCTTCATCAG TTACCTTTCA 
GACCGTGCCC AGCGCCAGGC CTTCCTGGAG ACCCGGAGGT GTGTGGAGGC CAGGCTCCGC 
TTGGAGACAG AGAACCAAAG ACAGGAGCGG CTTGTGCTGT CTGTGCTCCC CAGGTTTGTC 
GTCCTGGAAA TGATCAACGA CATGACCAAT GTGGAGGATG AGCACCTGCA GCATCAGTTC 
CACCGCATCT ACATCCATCG CTATGAGAAC GTCAGTATTC TTTTTGCAGA TGTCAAAGGA 
TTTACCAACC TCTCTACGAC CTTGTCTGCT CAGGAGCTGG TCAGGATGCT CAACGAACTC 
TTTGCCAGAT TCGACCGGCT GGCCCATGAG CATCACTGTC TTCGCATTAA AATCCTGGGG 
GACTGCTACT ACTGTGTGTC TGGACTGCCT GAGCCCCGCC GGGACCACGC TCATTGCTGT 
GTTGAAATGG GCCTCAGCAT GATCAAAACT ATCAGGTTTG TGAGATCCAG AACGAAGCAC 
GATGTTGACA TGCGAATTGG AATCCATTCA GGTTCTGTGC TATGTGGTGT GTTGGGCCTG 
AGGAAATGGC AGTTTGATGT CTGGTCTTGG GATGTGGACA TAGCAAACAA GCTTGAGTCT 
GGAGGAATCC CTGGGAGGAT TCACATTTCT AAAGCCACCC TGGATTGCCT CAATGGTGAC 
TATAACGTGG AAGAGGGTCA CGGGAAAGAG AGGAACGAAT TCTTGAGGAA GCATAACATA 
GAGACCTATT TGATTAAGCA GCCTGAGGAG AGTTTGCTCT GCTTGCCTGA AGACATCGTT 
AAGGAGTCGG TGAGCTGCTC TGACAGGAGA AACAGTGGAG CAACATTCAC AGAAGGATCG 
TGGAGCCCAG AGCTGCCTTT CGACAACATC GTGGGCAAAC AGAATACTCT GGCTGCCCTA 
ACAAGAAATT CAATAAATCT GCTTCCAAAC CATCTCGCAC AAGCTTTGCA TGTCCAGTCT 
GGGCCTGAGG AAATTAACAA GAGAATAGAG CATACCATCG ACTTGCGGAG TGGCGATAAG 
TTGAGAAGAG AGCATATCAA GCCATTCTCA CTGATGTTTA AAGACTCCAG CCTGGAGCAC 
AAGTATTCTC AAATGAGGGA TGAAGTATTC AAGTCAAACT TGGTCTGTGC ATTTATCGTT 
CTTCTGTTTA TCACTGCAAT TCAAAGTTTG CTTCCTTCTT CAAGGCTGAT GCCTATGACT 
ATCCAGTTCT CCATCCTGAT CATGCTGCAC TCTGCCCTGG TCCTCATCAC CACAGCAGAA 
GACTATAAGT GTCTGCCCCT CATCCTCCGA AAAACCTGCT GTTGGATTAA TGAGACCTAT 
CTGGCCCGCA ACGTCATCAT CTTCGCTTCC ATCTTAATTA ACTTCCTGGG AGCTGTCCTA 
AATATTTACT TTGTCTTCAC TGGGGTGTTG GCCATGGTGA CCTGTGCTGT GTTTCTACGG 
CTTAACTCTG TCCTGAAGCT GGCAGTGCTA CTCATCATGA TCGCCATCTA CGCCCTGCTC 
ACAGAGACCA TCTACGCAGG TCTCTTTCTG AGTTATGACA ACCTGAACCA CAGTGGAGAA 
GATTTCCTGG GGACCAAGGA AGCATCACTG CTGCTGATGG CCATGTTCCT TCTTGCTGTG 
TTCTACCATG GACAACAGCT GGAGTACACA GCCCGCCTGG ATTTCCTGTG GCGCGTACAG 
GCCAAAGAGG AGATCAACGA GATGAAGGAA CTGAGGGAAC ACAACGAGAA CATGCTGCGC 
AATATCTTAC CCAGCCATGT GGCCCGCCAC TTCCTGGAGA AAGACAGAGA CAATGAGGAG 
CTGTATTCTC AATCCTACGA TGCTGTTGGA GTGATGTTCG CCTCCATCCC TGGGTTCGCA 
GACTTCTACT CTCAGACAGA AATGAACAAC CAGGGAGTAG AATGTCTGCG CTTGCTGAAT 
GAGATCATTG CTGACTTTGA TGAGCTGCTC GGGGAGGACC GGTTTCAGGA CATTGAGAAG 
ATTAAGACCA TTGGTAGTAC ATACATGGCT GTCTCAGGAC TGTCCCCAGA GAAACAGCAA 
TGTGAAGATA AATGGGGACA TTTGTGTGCC CTGGCTGACT TCTCTCTTGC TCTGACTGAA 
AGCATACAAG AGATCAACAA GCATTCATTC AACAATTTTG AACTCCGAAT CGGCATCAGC 
CATGGCTCAG TGGTGGCAGG TGTAATTGGA GCTAAGAAAC CACAGTATGA CATTTGGGGG 
AAAACTGTGA ACTTGGCAAG CCGAATGGAC AGCACGGGAG TAAGTGGCCG GATCCAAGTT 
CCTGAGGAGA CCTACCTTAT CCTGAAGGAC CAGGGCTTTG CCTTTGACTA CCGTGGGGAG 
ATATATGTGA AGGGCATCAG TGAACAAGAA GGGAAAATCA AAACATACTT TCTCCTGGGA 
CGAGTCCAAC CCAACCCATT CATCTTACCC CCAAGGAGAC TTCCCGGGCA ATACTCTCTG 
GCTGCGGTTG TCCTTGGCCT TGTCCAGTCT CTCAACAGGC AAAGGCAGAA GCAACTTCTC 
AACGAGAACA GCAATTCGGG CATCATCAAG AGCCATTACA ACCGGCGGAC TTTGCTAACG 
CCAAGTGGGC CAGAGCCTGG AGCACAAGCT GAAGGCACTG ACAAATCCGA TTTGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001278832.1
CDS	1192..4851
Translation	MELSDVHCLSGSEELYTIQPTPPAGDDGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGGGVSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGPGERAHNTGGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDNTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVTLQVLIPRLAVFSINQVLAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRRDHAHCCVEMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLCLPEDIVKESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRLMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAVLNIYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENSNSGIIKSHYNRRTLLTPSGPEPGAQAEGTDKSDLP

Target ORF information:

RefSeq Version	NM_001291903.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001291903.1

ORF Insert Sequence:

ATGGAGCTCT CGGATGTGCA CTGCCTTAGT GGCAGCGAGG AACTCTACAC CATCCAACCG 
ACGCCCCCGG CCGGCGACGA CGGGAGCGGC TCTCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGGC ACATCACGGA GCAGCGCTTC ATCCACGGGC ACCGAGGCGG CGGCGGCGGC 
GGGGTCTCCC GCAAAGCCTC GAACCCTGCG GGCAGTGGAC CCAATCACCA CGCGCCGCAG 
CTGTCTAGCG ACTCGGTGCT GCCTCTCTAT TCTCTGGGCC CCGGAGAGCG AGCGCACAAC 
ACCGGTGGCA CCAAAGTCTT TCCGGAACGC AGCGGGAGCG GCAGTGCCAG TGGCAGCGGG 
GGCGGGGGCG ACTTGGGCTT CCTACACCTT GACTGTGCCC CAAGTAACTC GGATTTCTTC 
CTCAATGGAG GATACAGCTA CCGAGGGGTC ATTTTTCCAA CCCTACGCAA CTCCTTCAAG 
TCTCGGGATC TGGAGCGCCT CTACCAACGC TATTTCCTGG GCCAGAGGCG CAAATCGGAG 
GTAGTGATGA ACGTGTTGGA TGTACTAACC AAACTCACCC TTTTAGTCCT GCACTTGAGC 
CTGGCCTCGG CTCCAATGGA CCCTCTCAAG GGCATCCTGC TAGGCTTTTT CACTGGCATC 
GAGGTGGTGA TCTGCGCCCT CGTGGTGGTC AGGAAGGACA ACACCTCCCA CACTTACCTG 
CAATACAGCG GCGTGGTCAC TTGGGTGGCT ATGACCACCC AGATTCTGGC AGCAGGCCTG 
GGCTATGGGC TTCTGGGCGA CGGCATAGGC TACGTGCTTT TTACACTCTT CGCCACCTAC 
AGCATGCTTC CCCTGCCTCT CACCTGGGCC ATCTTGGCCG GCCTGGGCAC ATCTTTGCTG 
CAAGTCACCC TTCAAGTACT CATACCCAGG CTAGCGGTCT TTTCCATCAA CCAGGTCCTG 
GCCCAGGTGG TGCTATTCAT GTGTATGAAT ACAGCAGGAA TCTTCATCAG TTACCTTTCA 
GACCGTGCCC AGCGCCAGGC CTTCCTGGAG ACCCGGAGGT GTGTGGAGGC CAGGCTCCGC 
TTGGAGACAG AGAACCAAAG ACAGGAGCGG CTTGTGCTGT CTGTGCTCCC CAGGTTTGTC 
GTCCTGGAAA TGATCAACGA CATGACCAAT GTGGAGGATG AGCACCTGCA GCATCAGTTC 
CACCGCATCT ACATCCATCG CTATGAGAAC GTCAGTATTC TTTTTGCAGA TGTCAAAGGA 
TTTACCAACC TCTCTACGAC CTTGTCTGCT CAGGAGCTGG TCAGGATGCT CAACGAACTC 
TTTGCCAGAT TCGACCGGCT GGCCCATGAG CATCACTGTC TTCGCATTAA AATCCTGGGG 
GACTGCTACT ACTGTGTGTC TGGACTGCCT GAGCCCCGCC GGGACCACGC TCATTGCTGT 
GTTGAAATGG GCCTCAGCAT GATCAAAACT ATCAGGTTTG TGAGATCCAG AACGAAGCAC 
GATGTTGACA TGCGAATTGG AATCCATTCA GGTTCTGTGC TATGTGGTGT GTTGGGCCTG 
AGGAAATGGC AGTTTGATGT CTGGTCTTGG GATGTGGACA TAGCAAACAA GCTTGAGTCT 
GGAGGAATCC CTGGGAGGAT TCACATTTCT AAAGCCACCC TGGATTGCCT CAATGGTGAC 
TATAACGTGG AAGAGGGTCA CGGGAAAGAG AGGAACGAAT TCTTGAGGAA GCATAACATA 
GAGACCTATT TGATTAAGCA GCCTGAGGAG AGTTTGCTCT GCTTGCCTGA AGACATCGTT 
AAGGAGTCGG TGAGCTGCTC TGACAGGAGA AACAGTGGAG CAACATTCAC AGAAGGATCG 
TGGAGCCCAG AGCTGCCTTT CGACAACATC GTGGGCAAAC AGAATACTCT GGCTGCCCTA 
ACAAGAAATT CAATAAATCT GCTTCCAAAC CATCTCGCAC AAGCTTTGCA TGTCCAGTCT 
GGGCCTGAGG AAATTAACAA GAGAATAGAG CATACCATCG ACTTGCGGAG TGGCGATAAG 
TTGAGAAGAG AGCATATCAA GCCATTCTCA CTGATGTTTA AAGACTCCAG CCTGGAGCAC 
AAGTATTCTC AAATGAGGGA TGAAGTATTC AAGTCAAACT TGGTCTGTGC ATTTATCGTT 
CTTCTGTTTA TCACTGCAAT TCAAAGTTTG CTTCCTTCTT CAAGGCTGAT GCCTATGACT 
ATCCAGTTCT CCATCCTGAT CATGCTGCAC TCTGCCCTGG TCCTCATCAC CACAGCAGAA 
GACTATAAGT GTCTGCCCCT CATCCTCCGA AAAACCTGCT GTTGGATTAA TGAGACCTAT 
CTGGCCCGCA ACGTCATCAT CTTCGCTTCC ATCTTAATTA ACTTCCTGGG AGCTGTCCTA 
AATATTTACT TTGTCTTCAC TGGGGTGTTG GCCATGGTGA CCTGTGCTGT GTTTCTACGG 
CTTAACTCTG TCCTGAAGCT GGCAGTGCTA CTCATCATGA TCGCCATCTA CGCCCTGCTC 
ACAGAGACCA TCTACGCAGG TCTCTTTCTG AGTTATGACA ACCTGAACCA CAGTGGAGAA 
GATTTCCTGG GGACCAAGGA AGCATCACTG CTGCTGATGG CCATGTTCCT TCTTGCTGTG 
TTCTACCATG GACAACAGCT GGAGTACACA GCCCGCCTGG ATTTCCTGTG GCGCGTACAG 
GCCAAAGAGG AGATCAACGA GATGAAGGAA CTGAGGGAAC ACAACGAGAA CATGCTGCGC 
AATATCTTAC CCAGCCATGT GGCCCGCCAC TTCCTGGAGA AAGACAGAGA CAATGAGGAG 
CTGTATTCTC AATCCTACGA TGCTGTTGGA GTGATGTTCG CCTCCATCCC TGGGTTCGCA 
GACTTCTACT CTCAGACAGA AATGAACAAC CAGGGAGTAG AATGTCTGCG CTTGCTGAAT 
GAGATCATTG CTGACTTTGA TGAGCTGCTC GGGGAGGACC GGTTTCAGGA CATTGAGAAG 
ATTAAGACCA TTGGTAGTAC ATACATGGCT GTCTCAGGAC TGTCCCCAGA GAAACAGCAA 
TGTGAAGATA AATGGGGACA TTTGTGTGCC CTGGCTGACT TCTCTCTTGC TCTGACTGAA 
AGCATACAAG AGATCAACAA GCATTCATTC AACAATTTTG AACTCCGAAT CGGCATCAGC 
CATGGCTCAG TGGTGGCAGG TGTAATTGGA GCTAAGAAAC CACAGTATGA CATTTGGGGG 
AAAACTGTGA ACTTGGCAAG CCGAATGGAC AGCACGGGAG TAAGTGGCCG GATCCAAGTT 
CCTGAGGAGA CCTACCTTAT CCTGAAGGAC CAGGGCTTTG CCTTTGACTA CCGTGGGGAG 
ATATATGTGA AGGGCATCAG TGAACAAGAA GGGAAAATCA AAACATACTT TCTCCTGGGA 
CGAGTCCAAC CCAACCCATT CATCTTACCC CCAAGGAGAC TTCCCGGGCA ATACTCTCTG 
GCTGCGGTTG TCCTTGGCCT TGTCCAGTCT CTCAACAGGC AAAGGCAGAA GCAACTTCTC 
AACGAGAACA GCAATTCGGG CATCATCAAG AGCCATTACA ACCGGCGGAC TTTGCTAACG 
CCAAGTGGGC CAGAGCCTGG AGCACAAGCT GAAGGCACTG ACAAATCCGA TTTGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcy8 ( NM_009623.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033753.2 Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu23616
Clone ID Related Accession (Same CDS sequence)	NM_009623.2
Accession Version	NM_009623.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	adenylate cyclase type 8 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK138244.1 and BC094231.1. On Feb 3, 2007 this sequence version replaced NM_009623.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U85021.1, SRR1660821.158342.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849377, SAMN00849378 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTCT CGGATGTGCA CTGCCTTAGT GGCAGCGAGG AACTCTACAC CATCCAACCG 
ACGCCCCCGG CCGGCGACGA CGGGAGCGGC TCTCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGGC ACATCACGGA GCAGCGCTTC ATCCACGGGC ACCGAGGCGG CGGCGGCGGC 
GGGGTCTCCC GCAAAGCCTC GAACCCTGCG GGCAGTGGAC CCAATCACCA CGCGCCGCAG 
CTGTCTAGCG ACTCGGTGCT GCCTCTCTAT TCTCTGGGCC CCGGAGAGCG AGCGCACAAC 
ACCGGTGGCA CCAAAGTCTT TCCGGAACGC AGCGGGAGCG GCAGTGCCAG TGGCAGCGGG 
GGCGGGGGCG ACTTGGGCTT CCTACACCTT GACTGTGCCC CAAGTAACTC GGATTTCTTC 
CTCAATGGAG GATACAGCTA CCGAGGGGTC ATTTTTCCAA CCCTACGCAA CTCCTTCAAG 
TCTCGGGATC TGGAGCGCCT CTACCAACGC TATTTCCTGG GCCAGAGGCG CAAATCGGAG 
GTAGTGATGA ACGTGTTGGA TGTACTAACC AAACTCACCC TTTTAGTCCT GCACTTGAGC 
CTGGCCTCGG CTCCAATGGA CCCTCTCAAG GGCATCCTGC TAGGCTTTTT CACTGGCATC 
GAGGTGGTGA TCTGCGCCCT CGTGGTGGTC AGGAAGGACA ACACCTCCCA CACTTACCTG 
CAATACAGCG GCGTGGTCAC TTGGGTGGCT ATGACCACCC AGATTCTGGC AGCAGGCCTG 
GGCTATGGGC TTCTGGGCGA CGGCATAGGC TACGTGCTTT TTACACTCTT CGCCACCTAC 
AGCATGCTTC CCCTGCCTCT CACCTGGGCC ATCTTGGCCG GCCTGGGCAC ATCTTTGCTG 
CAAGTCACCC TTCAAGTACT CATACCCAGG CTAGCGGTCT TTTCCATCAA CCAGGTCCTG 
GCCCAGGTGG TGCTATTCAT GTGTATGAAT ACAGCAGGAA TCTTCATCAG TTACCTTTCA 
GACCGTGCCC AGCGCCAGGC CTTCCTGGAG ACCCGGAGGT GTGTGGAGGC CAGGCTCCGC 
TTGGAGACAG AGAACCAAAG ACAGGAGCGG CTTGTGCTGT CTGTGCTCCC CAGGTTTGTC 
GTCCTGGAAA TGATCAACGA CATGACCAAT GTGGAGGATG AGCACCTGCA GCATCAGTTC 
CACCGCATCT ACATCCATCG CTATGAGAAC GTCAGTATTC TTTTTGCAGA TGTCAAAGGA 
TTTACCAACC TCTCTACGAC CTTGTCTGCT CAGGAGCTGG TCAGGATGCT CAACGAACTC 
TTTGCCAGAT TCGACCGGCT GGCCCATGAG CATCACTGTC TTCGCATTAA AATCCTGGGG 
GACTGCTACT ACTGTGTGTC TGGACTGCCT GAGCCCCGCC GGGACCACGC TCATTGCTGT 
GTTGAAATGG GCCTCAGCAT GATCAAAACT ATCAGGTTTG TGAGATCCAG AACGAAGCAC 
GATGTTGACA TGCGAATTGG AATCCATTCA GGTTCTGTGC TATGTGGTGT GTTGGGCCTG 
AGGAAATGGC AGTTTGATGT CTGGTCTTGG GATGTGGACA TAGCAAACAA GCTTGAGTCT 
GGAGGAATCC CTGGGAGGAT TCACATTTCT AAAGCCACCC TGGATTGCCT CAATGGTGAC 
TATAACGTGG AAGAGGGTCA CGGGAAAGAG AGGAACGAAT TCTTGAGGAA GCATAACATA 
GAGACCTATT TGATTAAGCA GCCTGAGGAG AGTTTGCTCT GCTTGCCTGA AGACATCGTT 
AAGGAGTCGG TGAGCTGCTC TGACAGGAGA AACAGTGGAG CAACATTCAC AGAAGGATCG 
TGGAGCCCAG AGCTGCCTTT CGACAACATC GTGGGCAAAC AGAATACTCT GGCTGCCCTA 
ACAAGAAATT CAATAAATCT GCTTCCAAAC CATCTCGCAC AAGCTTTGCA TGTCCAGTCT 
GGGCCTGAGG AAATTAACAA GAGAATAGAG CATACCATCG ACTTGCGGAG TGGCGATAAG 
TTGAGAAGAG AGCATATCAA GCCATTCTCA CTGATGTTTA AAGACTCCAG CCTGGAGCAC 
AAGTATTCTC AAATGAGGGA TGAAGTATTC AAGTCAAACT TGGTCTGTGC ATTTATCGTT 
CTTCTGTTTA TCACTGCAAT TCAAAGTTTG CTTCCTTCTT CAAGGCTGAT GCCTATGACT 
ATCCAGTTCT CCATCCTGAT CATGCTGCAC TCTGCCCTGG TCCTCATCAC CACAGCAGAA 
GACTATAAGT GTCTGCCCCT CATCCTCCGA AAAACCTGCT GTTGGATTAA TGAGACCTAT 
CTGGCCCGCA ACGTCATCAT CTTCGCTTCC ATCTTAATTA ACTTCCTGGG AGCTGTCCTA 
AATATTCTGT GGTGTGATTT TGACAAGTCG ATACCCTTGA AGAACCTGAC TTTCAATTCC 
TCAGCTGTGT TTACAGATAT CTGCTCCTAC CCAGAGTACT TTGTCTTCAC TGGGGTGTTG 
GCCATGGTGA CCTGTGCTGT GTTTCTACGG CTTAACTCTG TCCTGAAGCT GGCAGTGCTA 
CTCATCATGA TCGCCATCTA CGCCCTGCTC ACAGAGACCA TCTACGCAGG TCTCTTTCTG 
AGTTATGACA ACCTGAACCA CAGTGGAGAA GATTTCCTGG GGACCAAGGA AGCATCACTG 
CTGCTGATGG CCATGTTCCT TCTTGCTGTG TTCTACCATG GACAACAGCT GGAGTACACA 
GCCCGCCTGG ATTTCCTGTG GCGCGTACAG GCCAAAGAGG AGATCAACGA GATGAAGGAA 
CTGAGGGAAC ACAACGAGAA CATGCTGCGC AATATCTTAC CCAGCCATGT GGCCCGCCAC 
TTCCTGGAGA AAGACAGAGA CAATGAGGAG CTGTATTCTC AATCCTACGA TGCTGTTGGA 
GTGATGTTCG CCTCCATCCC TGGGTTCGCA GACTTCTACT CTCAGACAGA AATGAACAAC 
CAGGGAGTAG AATGTCTGCG CTTGCTGAAT GAGATCATTG CTGACTTTGA TGAGCTGCTC 
GGGGAGGACC GGTTTCAGGA CATTGAGAAG ATTAAGACCA TTGGTAGTAC ATACATGGCT 
GTCTCAGGAC TGTCCCCAGA GAAACAGCAA TGTGAAGATA AATGGGGACA TTTGTGTGCC 
CTGGCTGACT TCTCTCTTGC TCTGACTGAA AGCATACAAG AGATCAACAA GCATTCATTC 
AACAATTTTG AACTCCGAAT CGGCATCAGC CATGGCTCAG TGGTGGCAGG TGTAATTGGA 
GCTAAGAAAC CACAGTATGA CATTTGGGGG AAAACTGTGA ACTTGGCAAG CCGAATGGAC 
AGCACGGGAG TAAGTGGCCG GATCCAAGTT CCTGAGGAGA CCTACCTTAT CCTGAAGGAC 
CAGGGCTTTG CCTTTGACTA CCGTGGGGAG ATATATGTGA AGGGCATCAG TGAACAAGAA 
GGGAAAATCA AAACATACTT TCTCCTGGGA CGAGTCCAAC CCAACCCATT CATCTTACCC 
CCAAGGAGAC TTCCCGGGCA ATACTCTCTG GCTGCGGTTG TCCTTGGCCT TGTCCAGTCT 
CTCAACAGGC AAAGGCAGAA GCAACTTCTC AACGAGAACA GCAATTCGGG CATCATCAAG 
AGCCATTACA ACCGGCGGAC TTTGCTAACG CCAAGTGGGC CAGAGCCTGG AGCACAAGCT 
GAAGGCACTG ACAAATCCGA TTTGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033753.2
CDS	1192..4941
Translation	MELSDVHCLSGSEELYTIQPTPPAGDDGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGGGVSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGPGERAHNTGGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDNTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVTLQVLIPRLAVFSINQVLAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRRDHAHCCVEMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLCLPEDIVKESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRLMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAVLNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENSNSGIIKSHYNRRTLLTPSGPEPGAQAEGTDKSDLP

Target ORF information:

RefSeq Version	NM_009623.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009623.2

ORF Insert Sequence:

ATGGAGCTCT CGGATGTGCA CTGCCTTAGT GGCAGCGAGG AACTCTACAC CATCCAACCG 
ACGCCCCCGG CCGGCGACGA CGGGAGCGGC TCTCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGGC ACATCACGGA GCAGCGCTTC ATCCACGGGC ACCGAGGCGG CGGCGGCGGC 
GGGGTCTCCC GCAAAGCCTC GAACCCTGCG GGCAGTGGAC CCAATCACCA CGCGCCGCAG 
CTGTCTAGCG ACTCGGTGCT GCCTCTCTAT TCTCTGGGCC CCGGAGAGCG AGCGCACAAC 
ACCGGTGGCA CCAAAGTCTT TCCGGAACGC AGCGGGAGCG GCAGTGCCAG TGGCAGCGGG 
GGCGGGGGCG ACTTGGGCTT CCTACACCTT GACTGTGCCC CAAGTAACTC GGATTTCTTC 
CTCAATGGAG GATACAGCTA CCGAGGGGTC ATTTTTCCAA CCCTACGCAA CTCCTTCAAG 
TCTCGGGATC TGGAGCGCCT CTACCAACGC TATTTCCTGG GCCAGAGGCG CAAATCGGAG 
GTAGTGATGA ACGTGTTGGA TGTACTAACC AAACTCACCC TTTTAGTCCT GCACTTGAGC 
CTGGCCTCGG CTCCAATGGA CCCTCTCAAG GGCATCCTGC TAGGCTTTTT CACTGGCATC 
GAGGTGGTGA TCTGCGCCCT CGTGGTGGTC AGGAAGGACA ACACCTCCCA CACTTACCTG 
CAATACAGCG GCGTGGTCAC TTGGGTGGCT ATGACCACCC AGATTCTGGC AGCAGGCCTG 
GGCTATGGGC TTCTGGGCGA CGGCATAGGC TACGTGCTTT TTACACTCTT CGCCACCTAC 
AGCATGCTTC CCCTGCCTCT CACCTGGGCC ATCTTGGCCG GCCTGGGCAC ATCTTTGCTG 
CAAGTCACCC TTCAAGTACT CATACCCAGG CTAGCGGTCT TTTCCATCAA CCAGGTCCTG 
GCCCAGGTGG TGCTATTCAT GTGTATGAAT ACAGCAGGAA TCTTCATCAG TTACCTTTCA 
GACCGTGCCC AGCGCCAGGC CTTCCTGGAG ACCCGGAGGT GTGTGGAGGC CAGGCTCCGC 
TTGGAGACAG AGAACCAAAG ACAGGAGCGG CTTGTGCTGT CTGTGCTCCC CAGGTTTGTC 
GTCCTGGAAA TGATCAACGA CATGACCAAT GTGGAGGATG AGCACCTGCA GCATCAGTTC 
CACCGCATCT ACATCCATCG CTATGAGAAC GTCAGTATTC TTTTTGCAGA TGTCAAAGGA 
TTTACCAACC TCTCTACGAC CTTGTCTGCT CAGGAGCTGG TCAGGATGCT CAACGAACTC 
TTTGCCAGAT TCGACCGGCT GGCCCATGAG CATCACTGTC TTCGCATTAA AATCCTGGGG 
GACTGCTACT ACTGTGTGTC TGGACTGCCT GAGCCCCGCC GGGACCACGC TCATTGCTGT 
GTTGAAATGG GCCTCAGCAT GATCAAAACT ATCAGGTTTG TGAGATCCAG AACGAAGCAC 
GATGTTGACA TGCGAATTGG AATCCATTCA GGTTCTGTGC TATGTGGTGT GTTGGGCCTG 
AGGAAATGGC AGTTTGATGT CTGGTCTTGG GATGTGGACA TAGCAAACAA GCTTGAGTCT 
GGAGGAATCC CTGGGAGGAT TCACATTTCT AAAGCCACCC TGGATTGCCT CAATGGTGAC 
TATAACGTGG AAGAGGGTCA CGGGAAAGAG AGGAACGAAT TCTTGAGGAA GCATAACATA 
GAGACCTATT TGATTAAGCA GCCTGAGGAG AGTTTGCTCT GCTTGCCTGA AGACATCGTT 
AAGGAGTCGG TGAGCTGCTC TGACAGGAGA AACAGTGGAG CAACATTCAC AGAAGGATCG 
TGGAGCCCAG AGCTGCCTTT CGACAACATC GTGGGCAAAC AGAATACTCT GGCTGCCCTA 
ACAAGAAATT CAATAAATCT GCTTCCAAAC CATCTCGCAC AAGCTTTGCA TGTCCAGTCT 
GGGCCTGAGG AAATTAACAA GAGAATAGAG CATACCATCG ACTTGCGGAG TGGCGATAAG 
TTGAGAAGAG AGCATATCAA GCCATTCTCA CTGATGTTTA AAGACTCCAG CCTGGAGCAC 
AAGTATTCTC AAATGAGGGA TGAAGTATTC AAGTCAAACT TGGTCTGTGC ATTTATCGTT 
CTTCTGTTTA TCACTGCAAT TCAAAGTTTG CTTCCTTCTT CAAGGCTGAT GCCTATGACT 
ATCCAGTTCT CCATCCTGAT CATGCTGCAC TCTGCCCTGG TCCTCATCAC CACAGCAGAA 
GACTATAAGT GTCTGCCCCT CATCCTCCGA AAAACCTGCT GTTGGATTAA TGAGACCTAT 
CTGGCCCGCA ACGTCATCAT CTTCGCTTCC ATCTTAATTA ACTTCCTGGG AGCTGTCCTA 
AATATTCTGT GGTGTGATTT TGACAAGTCG ATACCCTTGA AGAACCTGAC TTTCAATTCC 
TCAGCTGTGT TTACAGATAT CTGCTCCTAC CCAGAGTACT TTGTCTTCAC TGGGGTGTTG 
GCCATGGTGA CCTGTGCTGT GTTTCTACGG CTTAACTCTG TCCTGAAGCT GGCAGTGCTA 
CTCATCATGA TCGCCATCTA CGCCCTGCTC ACAGAGACCA TCTACGCAGG TCTCTTTCTG 
AGTTATGACA ACCTGAACCA CAGTGGAGAA GATTTCCTGG GGACCAAGGA AGCATCACTG 
CTGCTGATGG CCATGTTCCT TCTTGCTGTG TTCTACCATG GACAACAGCT GGAGTACACA 
GCCCGCCTGG ATTTCCTGTG GCGCGTACAG GCCAAAGAGG AGATCAACGA GATGAAGGAA 
CTGAGGGAAC ACAACGAGAA CATGCTGCGC AATATCTTAC CCAGCCATGT GGCCCGCCAC 
TTCCTGGAGA AAGACAGAGA CAATGAGGAG CTGTATTCTC AATCCTACGA TGCTGTTGGA 
GTGATGTTCG CCTCCATCCC TGGGTTCGCA GACTTCTACT CTCAGACAGA AATGAACAAC 
CAGGGAGTAG AATGTCTGCG CTTGCTGAAT GAGATCATTG CTGACTTTGA TGAGCTGCTC 
GGGGAGGACC GGTTTCAGGA CATTGAGAAG ATTAAGACCA TTGGTAGTAC ATACATGGCT 
GTCTCAGGAC TGTCCCCAGA GAAACAGCAA TGTGAAGATA AATGGGGACA TTTGTGTGCC 
CTGGCTGACT TCTCTCTTGC TCTGACTGAA AGCATACAAG AGATCAACAA GCATTCATTC 
AACAATTTTG AACTCCGAAT CGGCATCAGC CATGGCTCAG TGGTGGCAGG TGTAATTGGA 
GCTAAGAAAC CACAGTATGA CATTTGGGGG AAAACTGTGA ACTTGGCAAG CCGAATGGAC 
AGCACGGGAG TAAGTGGCCG GATCCAAGTT CCTGAGGAGA CCTACCTTAT CCTGAAGGAC 
CAGGGCTTTG CCTTTGACTA CCGTGGGGAG ATATATGTGA AGGGCATCAG TGAACAAGAA 
GGGAAAATCA AAACATACTT TCTCCTGGGA CGAGTCCAAC CCAACCCATT CATCTTACCC 
CCAAGGAGAC TTCCCGGGCA ATACTCTCTG GCTGCGGTTG TCCTTGGCCT TGTCCAGTCT 
CTCAACAGGC AAAGGCAGAA GCAACTTCTC AACGAGAACA GCAATTCGGG CATCATCAAG 
AGCCATTACA ACCGGCGGAC TTTGCTAACG CCAAGTGGGC CAGAGCCTGG AGCACAAGCT 
GAAGGCACTG ACAAATCCGA TTTGCCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adcy8 ( NM_001331075.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001318004.1 Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 3, mRNA.

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CloneID	OMu50854
Clone ID Related Accession (Same CDS sequence)	NM_001331075.1
Accession Version	NM_001331075.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-26
Organism	Mus musculus(house mouse)
Product	adenylate cyclase type 8 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC116996.3, AC160934.2 and BC094231.1. On Sep 8, 2016 this sequence version replaced XM_006520319.3. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.65344.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849377, SAMN00849378 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTCT CGGATGTGCA CTGCCTTAGT GGCAGCGAGG AACTCTACAC CATCCAACCG 
ACGCCCCCGG CCGGCGACGA CGGGAGCGGC TCTCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGGC ACATCACGGA GCAGCGCTTC ATCCACGGGC ACCGAGGCGG CGGCGGCGGC 
GGGGTCTCCC GCAAAGCCTC GAACCCTGCG GGCAGTGGAC CCAATCACCA CGCGCCGCAG 
CTGTCTAGCG ACTCGGTGCT GCCTCTCTAT TCTCTGGGCC CCGGAGAGCG AGCGCACAAC 
ACCGGTGGCA CCAAAGTCTT TCCGGAACGC AGCGGGAGCG GCAGTGCCAG TGGCAGCGGG 
GGCGGGGGCG ACTTGGGCTT CCTACACCTT GACTGTGCCC CAAGTAACTC GGATTTCTTC 
CTCAATGGAG GATACAGCTA CCGAGGGGTC ATTTTTCCAA CCCTACGCAA CTCCTTCAAG 
TCTCGGGATC TGGAGCGCCT CTACCAACGC TATTTCCTGG GCCAGAGGCG CAAATCGGAG 
GTAGTGATGA ACGTGTTGGA TGTACTAACC AAACTCACCC TTTTAGTCCT GCACTTGAGC 
CTGGCCTCGG CTCCAATGGA CCCTCTCAAG GGCATCCTGC TAGGCTTTTT CACTGGCATC 
GAGGTGGTGA TCTGCGCCCT CGTGGTGGTC AGGAAGGACA ACACCTCCCA CACTTACCTG 
CAATACAGCG GCGTGGTCAC TTGGGTGGCT ATGACCACCC AGATTCTGGC AGCAGGCCTG 
GGCTATGGGC TTCTGGGCGA CGGCATAGGC TACGTGCTTT TTACACTCTT CGCCACCTAC 
AGCATGCTTC CCCTGCCTCT CACCTGGGCC ATCTTGGCCG GCCTGGGCAC ATCTTTGCTG 
CAAGTCACCC TTCAAGTACT CATACCCAGG CTAGCGGTCT TTTCCATCAA CCAGGTCCTG 
GCCCAGGTGG TGCTATTCAT GTGTATGAAT ACAGCAGGAA TCTTCATCAG TTACCTTTCA 
GACCGTGCCC AGCGCCAGGC CTTCCTGGAG ACCCGGAGGT GTGTGGAGGC CAGGCTCCGC 
TTGGAGACAG AGAACCAAAG ACAGGAGCGG CTTGTGCTGT CTGTGCTCCC CAGGTTTGTC 
GTCCTGGAAA TGATCAACGA CATGACCAAT GTGGAGGATG AGCACCTGCA GCATCAGTTC 
CACCGCATCT ACATCCATCG CTATGAGAAC GTCAGTATTC TTTTTGCAGA TGTCAAAGGA 
TTTACCAACC TCTCTACGAC CTTGTCTGCT CAGGAGCTGG TCAGGATGCT CAACGAACTC 
TTTGCCAGAT TCGACCGGCT GGCCCATGAG CATCACTGTC TTCGCATTAA AATCCTGGGG 
GACTGCTACT ACTGTGTGTC TGGACTGCCT GAGCCCCGCC GGGACCACGC TCATTGCTGT 
GTTGAAATGG GCCTCAGCAT GATCAAAACT ATCAGGTTTG TGAGATCCAG AACGAAGCAC 
GATGTTGACA TGCGAATTGG AATCCATTCA GGTTCTGTGC TATGTGGTGT GTTGGGCCTG 
AGGAAATGGC AGTTTGATGT CTGGTCTTGG GATGTGGACA TAGCAAACAA GCTTGAGTCT 
GGAGGAATCC CTGGGAGGAT TCACATTTCT AAAGCCACCC TGGATTGCCT CAATGGTGAC 
TATAACGTGG AAGAGGGTCA CGGGAAAGAG AGGAACGAAT TCTTGAGGAA GCATAACATA 
GAGACCTATT TGATTAAGCA GCCTGAGGAG AGTTTGCTCT GCTTGCCTGA AGACATCGTT 
AAGGAGTCGG TGAGCTGCTC TGACAGGAGA AACAGTGGAG CAACATTCAC AGAAGGATCG 
TGGAGCCCAG AGCTGCCTTT CGACAACATC GTGGGCAAAC AGAATTATTC TCAAATGAGG 
GATGAAGTAT TCAAGTCAAA CTTGGTCTGT GCATTTATCG TTCTTCTGTT TATCACTGCA 
ATTCAAAGTT TGCTTCCTTC TTCAAGGCTG ATGCCTATGA CTATCCAGTT CTCCATCCTG 
ATCATGCTGC ACTCTGCCCT GGTCCTCATC ACCACAGCAG AAGACTATAA GTGTCTGCCC 
CTCATCCTCC GAAAAACCTG CTGTTGGATT AATGAGACCT ATCTGGCCCG CAACGTCATC 
ATCTTCGCTT CCATCTTAAT TAACTTCCTG GGAGCTGTCC TAAATATTCT GTGGTGTGAT 
TTTGACAAGT CGATACCCTT GAAGAACCTG ACTTTCAATT CCTCAGCTGT GTTTACAGAT 
ATCTGCTCCT ACCCAGAGTA CTTTGTCTTC ACTGGGGTGT TGGCCATGGT GACCTGTGCT 
GTGTTTCTAC GGCTTAACTC TGTCCTGAAG CTGGCAGTGC TACTCATCAT GATCGCCATC 
TACGCCCTGC TCACAGAGAC CATCTACGCA GGTCTCTTTC TGAGTTATGA CAACCTGAAC 
CACAGTGGAG AAGATTTCCT GGGGACCAAG GAAGCATCAC TGCTGCTGAT GGCCATGTTC 
CTTCTTGCTG TGTTCTACCA TGGACAACAG CTGGAGTACA CAGCCCGCCT GGATTTCCTG 
TGGCGCGTAC AGGCCAAAGA GGAGATCAAC GAGATGAAGG AACTGAGGGA ACACAACGAG 
AACATGCTGC GCAATATCTT ACCCAGCCAT GTGGCCCGCC ACTTCCTGGA GAAAGACAGA 
GACAATGAGG AGCTGTATTC TCAATCCTAC GATGCTGTTG GAGTGATGTT CGCCTCCATC 
CCTGGGTTCG CAGACTTCTA CTCTCAGACA GAAATGAACA ACCAGGGAGT AGAATGTCTG 
CGCTTGCTGA ATGAGATCAT TGCTGACTTT GATGAGCTGC TCGGGGAGGA CCGGTTTCAG 
GACATTGAGA AGATTAAGAC CATTGGTAGT ACATACATGG CTGTCTCAGG ACTGTCCCCA 
GAGAAACAGC AATGTGAAGA TAAATGGGGA CATTTGTGTG CCCTGGCTGA CTTCTCTCTT 
GCTCTGACTG AAAGCATACA AGAGATCAAC AAGCATTCAT TCAACAATTT TGAACTCCGA 
ATCGGCATCA GCCATGGCTC AGTGGTGGCA GGTGTAATTG GAGCTAAGAA ACCACAGTAT 
GACATTTGGG GGAAAACTGT GAACTTGGCA AGCCGAATGG ACAGCACGGG AGTAAGTGGC 
CGGATCCAAG TTCCTGAGGA GACCTACCTT ATCCTGAAGG ACCAGGGCTT TGCCTTTGAC 
TACCGTGGGG AGATATATGT GAAGGGCATC AGTGAACAAG AAGGGAAAAT CAAAACATAC 
TTTCTCCTGG GACGAGTCCA ACCCAACCCA TTCATCTTAC CCCCAAGGAG ACTTCCCGGG 
CAATACTCTC TGGCTGCGGT TGTCCTTGGC CTTGTCCAGT CTCTCAACAG GCAAAGGCAG 
AAGCAACTTC TCAACGAGAA CAGCAATTCG GGCATCATCA AGAGCCATTA CAACCGGCGG 
ACTTTGCTAA CGCCAAGTGG GCCAGAGCCT GGAGCACAAG CTGAAGGCAC TGACAAATCC 
GATTTGCCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001318004.1
CDS	1192..4743
Translation	MELSDVHCLSGSEELYTIQPTPPAGDDGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGGGVSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGPGERAHNTGGTKVFPERSGSGSASGSGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDNTSHTYLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQVTLQVLIPRLAVFSINQVLAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRRDHAHCCVEMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLCLPEDIVKESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSRLMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAVLNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENSNSGIIKSHYNRRTLLTPSGPEPGAQAEGTDKSDLP

Target ORF information:

RefSeq Version	NM_001331075.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus adenylate cyclase 8 (Adcy8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001331075.1

ORF Insert Sequence:

ATGGAGCTCT CGGATGTGCA CTGCCTTAGT GGCAGCGAGG AACTCTACAC CATCCAACCG 
ACGCCCCCGG CCGGCGACGA CGGGAGCGGC TCTCGGCCGC AGCGGCTGCT GTGGCAGACG 
GCGGTGCGGC ACATCACGGA GCAGCGCTTC ATCCACGGGC ACCGAGGCGG CGGCGGCGGC 
GGGGTCTCCC GCAAAGCCTC GAACCCTGCG GGCAGTGGAC CCAATCACCA CGCGCCGCAG 
CTGTCTAGCG ACTCGGTGCT GCCTCTCTAT TCTCTGGGCC CCGGAGAGCG AGCGCACAAC 
ACCGGTGGCA CCAAAGTCTT TCCGGAACGC AGCGGGAGCG GCAGTGCCAG TGGCAGCGGG 
GGCGGGGGCG ACTTGGGCTT CCTACACCTT GACTGTGCCC CAAGTAACTC GGATTTCTTC 
CTCAATGGAG GATACAGCTA CCGAGGGGTC ATTTTTCCAA CCCTACGCAA CTCCTTCAAG 
TCTCGGGATC TGGAGCGCCT CTACCAACGC TATTTCCTGG GCCAGAGGCG CAAATCGGAG 
GTAGTGATGA ACGTGTTGGA TGTACTAACC AAACTCACCC TTTTAGTCCT GCACTTGAGC 
CTGGCCTCGG CTCCAATGGA CCCTCTCAAG GGCATCCTGC TAGGCTTTTT CACTGGCATC 
GAGGTGGTGA TCTGCGCCCT CGTGGTGGTC AGGAAGGACA ACACCTCCCA CACTTACCTG 
CAATACAGCG GCGTGGTCAC TTGGGTGGCT ATGACCACCC AGATTCTGGC AGCAGGCCTG 
GGCTATGGGC TTCTGGGCGA CGGCATAGGC TACGTGCTTT TTACACTCTT CGCCACCTAC 
AGCATGCTTC CCCTGCCTCT CACCTGGGCC ATCTTGGCCG GCCTGGGCAC ATCTTTGCTG 
CAAGTCACCC TTCAAGTACT CATACCCAGG CTAGCGGTCT TTTCCATCAA CCAGGTCCTG 
GCCCAGGTGG TGCTATTCAT GTGTATGAAT ACAGCAGGAA TCTTCATCAG TTACCTTTCA 
GACCGTGCCC AGCGCCAGGC CTTCCTGGAG ACCCGGAGGT GTGTGGAGGC CAGGCTCCGC 
TTGGAGACAG AGAACCAAAG ACAGGAGCGG CTTGTGCTGT CTGTGCTCCC CAGGTTTGTC 
GTCCTGGAAA TGATCAACGA CATGACCAAT GTGGAGGATG AGCACCTGCA GCATCAGTTC 
CACCGCATCT ACATCCATCG CTATGAGAAC GTCAGTATTC TTTTTGCAGA TGTCAAAGGA 
TTTACCAACC TCTCTACGAC CTTGTCTGCT CAGGAGCTGG TCAGGATGCT CAACGAACTC 
TTTGCCAGAT TCGACCGGCT GGCCCATGAG CATCACTGTC TTCGCATTAA AATCCTGGGG 
GACTGCTACT ACTGTGTGTC TGGACTGCCT GAGCCCCGCC GGGACCACGC TCATTGCTGT 
GTTGAAATGG GCCTCAGCAT GATCAAAACT ATCAGGTTTG TGAGATCCAG AACGAAGCAC 
GATGTTGACA TGCGAATTGG AATCCATTCA GGTTCTGTGC TATGTGGTGT GTTGGGCCTG 
AGGAAATGGC AGTTTGATGT CTGGTCTTGG GATGTGGACA TAGCAAACAA GCTTGAGTCT 
GGAGGAATCC CTGGGAGGAT TCACATTTCT AAAGCCACCC TGGATTGCCT CAATGGTGAC 
TATAACGTGG AAGAGGGTCA CGGGAAAGAG AGGAACGAAT TCTTGAGGAA GCATAACATA 
GAGACCTATT TGATTAAGCA GCCTGAGGAG AGTTTGCTCT GCTTGCCTGA AGACATCGTT 
AAGGAGTCGG TGAGCTGCTC TGACAGGAGA AACAGTGGAG CAACATTCAC AGAAGGATCG 
TGGAGCCCAG AGCTGCCTTT CGACAACATC GTGGGCAAAC AGAATTATTC TCAAATGAGG 
GATGAAGTAT TCAAGTCAAA CTTGGTCTGT GCATTTATCG TTCTTCTGTT TATCACTGCA 
ATTCAAAGTT TGCTTCCTTC TTCAAGGCTG ATGCCTATGA CTATCCAGTT CTCCATCCTG 
ATCATGCTGC ACTCTGCCCT GGTCCTCATC ACCACAGCAG AAGACTATAA GTGTCTGCCC 
CTCATCCTCC GAAAAACCTG CTGTTGGATT AATGAGACCT ATCTGGCCCG CAACGTCATC 
ATCTTCGCTT CCATCTTAAT TAACTTCCTG GGAGCTGTCC TAAATATTCT GTGGTGTGAT 
TTTGACAAGT CGATACCCTT GAAGAACCTG ACTTTCAATT CCTCAGCTGT GTTTACAGAT 
ATCTGCTCCT ACCCAGAGTA CTTTGTCTTC ACTGGGGTGT TGGCCATGGT GACCTGTGCT 
GTGTTTCTAC GGCTTAACTC TGTCCTGAAG CTGGCAGTGC TACTCATCAT GATCGCCATC 
TACGCCCTGC TCACAGAGAC CATCTACGCA GGTCTCTTTC TGAGTTATGA CAACCTGAAC 
CACAGTGGAG AAGATTTCCT GGGGACCAAG GAAGCATCAC TGCTGCTGAT GGCCATGTTC 
CTTCTTGCTG TGTTCTACCA TGGACAACAG CTGGAGTACA CAGCCCGCCT GGATTTCCTG 
TGGCGCGTAC AGGCCAAAGA GGAGATCAAC GAGATGAAGG AACTGAGGGA ACACAACGAG 
AACATGCTGC GCAATATCTT ACCCAGCCAT GTGGCCCGCC ACTTCCTGGA GAAAGACAGA 
GACAATGAGG AGCTGTATTC TCAATCCTAC GATGCTGTTG GAGTGATGTT CGCCTCCATC 
CCTGGGTTCG CAGACTTCTA CTCTCAGACA GAAATGAACA ACCAGGGAGT AGAATGTCTG 
CGCTTGCTGA ATGAGATCAT TGCTGACTTT GATGAGCTGC TCGGGGAGGA CCGGTTTCAG 
GACATTGAGA AGATTAAGAC CATTGGTAGT ACATACATGG CTGTCTCAGG ACTGTCCCCA 
GAGAAACAGC AATGTGAAGA TAAATGGGGA CATTTGTGTG CCCTGGCTGA CTTCTCTCTT 
GCTCTGACTG AAAGCATACA AGAGATCAAC AAGCATTCAT TCAACAATTT TGAACTCCGA 
ATCGGCATCA GCCATGGCTC AGTGGTGGCA GGTGTAATTG GAGCTAAGAA ACCACAGTAT 
GACATTTGGG GGAAAACTGT GAACTTGGCA AGCCGAATGG ACAGCACGGG AGTAAGTGGC 
CGGATCCAAG TTCCTGAGGA GACCTACCTT ATCCTGAAGG ACCAGGGCTT TGCCTTTGAC 
TACCGTGGGG AGATATATGT GAAGGGCATC AGTGAACAAG AAGGGAAAAT CAAAACATAC 
TTTCTCCTGG GACGAGTCCA ACCCAACCCA TTCATCTTAC CCCCAAGGAG ACTTCCCGGG 
CAATACTCTC TGGCTGCGGT TGTCCTTGGC CTTGTCCAGT CTCTCAACAG GCAAAGGCAG 
AAGCAACTTC TCAACGAGAA CAGCAATTCG GGCATCATCA AGAGCCATTA CAACCGGCGG 
ACTTTGCTAA CGCCAAGTGG GCCAGAGCCT GGAGCACAAG CTGAAGGCAC TGACAAATCC 
GATTTGCCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PBX transcription factors drive pulmonary vascular adaptation to birth.
The Journal of clinical investigation(2017 Dec)
McCulley DJ,Wienhold MD,Hines EA,Hacker TA,Rogers A,Pewowaruk RJ,Zewdu R,Chesler NC,Selleri L,Sun X

Memory Retrieval Re-Activates Erk1/2 Signaling in the Same Set of CA1 Neurons Recruited During Conditioning.
Neuroscience(2017 Mar)
Zamorano C,Fern?ndez-Albert J,Storm DR,Carn? X,Sindreu C

Calcium activated adenylyl cyclase AC8 but not AC1 is required for prolonged behavioral anxiety.
Molecular brain9(1)60(2016 05)
Bernabucci M,Zhuo M

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Adcy8 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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