TAB1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAB1
Entrez Gene ID	10454
Full Name	TGF-beta activated kinase 1 (MAP3K7) binding protein 1
Synonyms	3'-Tab1,MAP3K7IP1
General protein information	Preferred Names TGF-beta activated kinase 1 (MAP3K7) binding protein 1 Names TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TAK1-binding protein 1 mitogen-activated protein kinase kinase kinase 7-interacting protein 1 transforming growth factor beta-activated kinase-binding protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q13.1
Summary	The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
Disorder MIM:	602615

mRNA and Protein(s)

mRNA	Protein	Name
NM_006116.2	NP_006107.1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform alpha
NM_153497.2	NP_705717.1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform beta
NM_153497.3	NP_705717.1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform beta
NM_006116.3	NP_006107.1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform alpha

Pathways from BioSystems

Homologies

	TAB1	XP_002798398.1
Mus musculus (house mouse)	Tab1	NP_079885.2
Rattus norvegicus (Norway rat)	Tab1	NP_001103446.1
Homo sapiens (human)	TAB1	NP_006107.1
Canis lupus familiaris (dog)	TAB1	XP_538366.4
Pan troglodytes (chimpanzee)	TAB1	XP_515141.3
Gallus gallus (chicken)	TAB1	NP_001006240.1
Xenopus tropicalis (tropical clawed frog)	tab1	NP_001016463.1
Danio rerio (zebrafish)	tab1	XP_002662286.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002953	XP_311946.5

Gene Ontology
Bibliography

Related articles in PubMed

miR?873 inhibits colorectal cancer cell proliferation by targeting TRAF5 and TAB1.
Gong H, Fang L, Li Y, Du J, Zhou B, Wang X, Zhou H, Gao L, Wang K, Zhang J
Oncology reports(2018 Jan)

TAB1-induced auto-activation of p38? mitogen-activated protein kinase is crucially dependent on Threonine 185.
Thapa D, Nichols C, Bassi R, Martin ED, Verma S, Conte MR, De Santis V, De Nicola GF, Marber MS
Molecular and cellular biology(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we show that IL-1 induces robust p38a activation both in the nucleus and in the cytoplasm/membrane.Following stimulation, p38a activity returns to a basal level in absence of receptor degradation. While nuclear pulse is controlled by MKP1 through a negative feedback to pp38, its basal activity is controlled by both TAB1 and MKP1 through a positive feedback loop.
Title: Model Predicts That MKP1 and TAB1 Regulate p38? Nuclear Pulse and Its Basal Activity through Positive and Negative Feedback Loops in Response to IL-1.

TAK1/TAB1 expression in non-small cell lung carcinoma tissue is significantly increased and closely associated with patient clinical prognosis.
Title: Expression of TAK1/TAB1 expression in non-small cell lung carcinoma and adjacent normal tissues and their clinical significance.

Data indicate that mitogen-activated protein kinase (MAPK) p38 activation is triggered by AMP-activated protein kinases (AMPK) and mediated by TAB1 protein.
Title: The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells.

The amino acid sequence between positions 373 and 502 of TAB1 is required for TP interaction.
Title: TAB1: a target of triptolide in macrophages.

miR-29a repressed TAB1-mediated TIMP-1 production in dermal fibroblasts, demonstrating that miR-29a may be a therapeutic target in SSc.
Title: MiR-29a reduces TIMP-1 production by dermal fibroblasts via targeting TGF-? activated kinase 1 binding protein 1, implications for systemic sclerosis.

The following TAB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09656	NM_006116.3 Latest version!	Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant alpha, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu17802	NM_153497.3 Latest version!	Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant beta, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu17802	NM_153497.2	Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant beta, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu09656	NM_006116.2	Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant alpha, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAB1 ( NM_006116.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006107.1 Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant alpha, mRNA.

Price & Availability↑

CloneID	OHu09656
Clone ID Related Accession (Same CDS sequence)	NM_006116.2 , NM_006116.3
Accession Version	NM_006116.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC050554.1. On May 27, 2004 this sequence version replaced NM_006116.1. Transcript Variant: This variant (alpha) encodes the longer isoform (alpha). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC050554.1, SRR1163655.271787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGC AGAGGAGGAG CTTGCTGCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC 
CTGCCTCTCT GCCACCTCTC TGGGGTTGGC TCAGCCTCCA ACCGCAGCTA CTCTGCTGAT 
GGCAAGGGCA CTGAGAGCCA CCCGCCAGAG GACAGCTGGC TCAAGTTCAG GAGTGAGAAC 
AACTGCTTCC TGTATGGGGT CTTCAACGGC TATGATGGCA ACCGAGTGAC CAACTTCGTG 
GCCCAGCGGC TGTCCGCAGA GCTCCTGCTG GGCCAGCTGA ATGCCGAGCA CGCCGAGGCC 
GATGTGCGGC GTGTGCTGCT GCAGGCCTTC GATGTGGTGG AGAGGAGCTT CCTGGAGTCC 
ATTGACGACG CCTTGGCTGA GAAGGCAAGC CTCCAGTCGC AATTGCCAGA GGGAGTCCCT 
CAGCACCAGC TGCCTCCTCA GTATCAGAAG ATCCTTGAGA GACTCAAGAC GTTAGAGAGG 
GAAATTTCGG GAGGGGCCAT GGCCGTTGTG GCGGTCCTTC TCAACAACAA GCTCTACGTC 
GCCAATGTCG GTACAAACCG TGCACTTTTA TGCAAATCGA CAGTGGATGG GTTGCAGGTG 
ACACAGCTGA ACGTGGACCA CACCACAGAG AACGAGGATG AGCTCTTCCG TCTTTCGCAG 
CTGGGCTTGG ATGCTGGAAA GATCAAGCAG GTGGGGATCA TCTGTGGGCA GGAGAGCACC 
CGGCGGATCG GGGATTACAA GGTTAAATAT GGCTACACGG ACATTGACCT TCTCAGCGCT 
GCCAAGTCCA AACCAATCAT CGCAGAGCCA GAAATCCATG GGGCACAGCC GCTGGATGGG 
GTGACGGGCT TCTTGGTGCT GATGTCGGAG GGGTTGTACA AGGCCCTAGA GGCAGCCCAT 
GGGCCTGGGC AGGCCAACCA GGAGATTGCT GCGATGATTG ACACTGAGTT TGCCAAGCAG 
ACCTCCCTGG ACGCAGTGGC CCAGGCCGTC GTGGACCGGG TGAAGCGCAT CCACAGCGAC 
ACCTTCGCCA GTGGTGGGGA GCGTGCCAGG TTCTGCCCCC GGCACGAGGA CATGACCCTG 
CTAGTGAGGA ACTTTGGCTA CCCGCTGGGC GAAATGAGCC AGCCCACACC GAGCCCAGCC 
CCAGCTGCAG GAGGACGAGT GTACCCTGTG TCTGTGCCAT ACTCCAGCGC CCAGAGCACC 
AGCAAGACCA GCGTGACCCT CTCCCTTGTC ATGCCCTCCC AGGGCCAGAT GGTCAACGGG 
GCTCACAGTG CTTCCACCCT GGACGAAGCC ACCCCCACCC TCACCAACCA AAGCCCGACC 
TTAACCCTGC AGTCCACCAA CACGCACACG CAGAGCAGCA GCTCCAGCTC TGACGGAGGC 
CTCTTCCGCT CCCGGCCCGC CCACTCGCTC CCGCCTGGCG AGGACGGTCG TGTTGAGCCC 
TATGTGGACT TTGCTGAGTT TTACCGCCTC TGGAGCGTGG ACCATGGCGA GCAGAGCGTG 
GTGACAGCAC CGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006107.1
CDS	50..1564
Translation	MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVVTAP

Target ORF information:

RefSeq Version	NM_006116.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant alpha, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006116.2

ORF Insert Sequence:

ATGGCGGCGC AGAGGAGGAG CTTGCTGCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC 
CTGCCTCTCT GCCACCTCTC TGGGGTTGGC TCAGCCTCCA ACCGCAGCTA CTCTGCTGAT 
GGCAAGGGCA CTGAGAGCCA CCCGCCAGAG GACAGCTGGC TCAAGTTCAG GAGTGAGAAC 
AACTGCTTCC TGTATGGGGT CTTCAACGGC TATGATGGCA ACCGAGTGAC CAACTTCGTG 
GCCCAGCGGC TGTCCGCAGA GCTCCTGCTG GGCCAGCTGA ATGCCGAGCA CGCCGAGGCC 
GATGTGCGGC GTGTGCTGCT GCAGGCCTTC GATGTGGTGG AGAGGAGCTT CCTGGAGTCC 
ATTGACGACG CCTTGGCTGA GAAGGCAAGC CTCCAGTCGC AATTGCCAGA GGGAGTCCCT 
CAGCACCAGC TGCCTCCTCA GTATCAGAAG ATCCTTGAGA GACTCAAGAC GTTAGAGAGG 
GAAATTTCGG GAGGGGCCAT GGCCGTTGTG GCGGTCCTTC TCAACAACAA GCTCTACGTC 
GCCAATGTCG GTACAAACCG TGCACTTTTA TGCAAATCGA CAGTGGATGG GTTGCAGGTG 
ACACAGCTGA ACGTGGACCA CACCACAGAG AACGAGGATG AGCTCTTCCG TCTTTCGCAG 
CTGGGCTTGG ATGCTGGAAA GATCAAGCAG GTGGGGATCA TCTGTGGGCA GGAGAGCACC 
CGGCGGATCG GGGATTACAA GGTTAAATAT GGCTACACGG ACATTGACCT TCTCAGCGCT 
GCCAAGTCCA AACCAATCAT CGCAGAGCCA GAAATCCATG GGGCACAGCC GCTGGATGGG 
GTGACGGGCT TCTTGGTGCT GATGTCGGAG GGGTTGTACA AGGCCCTAGA GGCAGCCCAT 
GGGCCTGGGC AGGCCAACCA GGAGATTGCT GCGATGATTG ACACTGAGTT TGCCAAGCAG 
ACCTCCCTGG ACGCAGTGGC CCAGGCCGTC GTGGACCGGG TGAAGCGCAT CCACAGCGAC 
ACCTTCGCCA GTGGTGGGGA GCGTGCCAGG TTCTGCCCCC GGCACGAGGA CATGACCCTG 
CTAGTGAGGA ACTTTGGCTA CCCGCTGGGC GAAATGAGCC AGCCCACACC GAGCCCAGCC 
CCAGCTGCAG GAGGACGAGT GTACCCTGTG TCTGTGCCAT ACTCCAGCGC CCAGAGCACC 
AGCAAGACCA GCGTGACCCT CTCCCTTGTC ATGCCCTCCC AGGGCCAGAT GGTCAACGGG 
GCTCACAGTG CTTCCACCCT GGACGAAGCC ACCCCCACCC TCACCAACCA AAGCCCGACC 
TTAACCCTGC AGTCCACCAA CACGCACACG CAGAGCAGCA GCTCCAGCTC TGACGGAGGC 
CTCTTCCGCT CCCGGCCCGC CCACTCGCTC CCGCCTGGCG AGGACGGTCG TGTTGAGCCC 
TATGTGGACT TTGCTGAGTT TTACCGCCTC TGGAGCGTGG ACCATGGCGA GCAGAGCGTG 
GTGACAGCAC CGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TAB1 ( NM_006116.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006107.1 Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant alpha, mRNA.

Price & Availability↑

CloneID	OHu09656
Clone ID Related Accession (Same CDS sequence)	NM_006116.2 , NM_006116.3
Accession Version	NM_006116.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC050554.1. On Nov 22, 2018 this sequence version replaced NM_006116.2. Transcript Variant: This variant (alpha) encodes the longer isoform (alpha). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC038582.1, SRR1163655.271787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000216160.11/ ENSP00000216160.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGC AGAGGAGGAG CTTGCTGCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC 
CTGCCTCTCT GCCACCTCTC TGGGGTTGGC TCAGCCTCCA ACCGCAGCTA CTCTGCTGAT 
GGCAAGGGCA CTGAGAGCCA CCCGCCAGAG GACAGCTGGC TCAAGTTCAG GAGTGAGAAC 
AACTGCTTCC TGTATGGGGT CTTCAACGGC TATGATGGCA ACCGAGTGAC CAACTTCGTG 
GCCCAGCGGC TGTCCGCAGA GCTCCTGCTG GGCCAGCTGA ATGCCGAGCA CGCCGAGGCC 
GATGTGCGGC GTGTGCTGCT GCAGGCCTTC GATGTGGTGG AGAGGAGCTT CCTGGAGTCC 
ATTGACGACG CCTTGGCTGA GAAGGCAAGC CTCCAGTCGC AATTGCCAGA GGGAGTCCCT 
CAGCACCAGC TGCCTCCTCA GTATCAGAAG ATCCTTGAGA GACTCAAGAC GTTAGAGAGG 
GAAATTTCGG GAGGGGCCAT GGCCGTTGTG GCGGTCCTTC TCAACAACAA GCTCTACGTC 
GCCAATGTCG GTACAAACCG TGCACTTTTA TGCAAATCGA CAGTGGATGG GTTGCAGGTG 
ACACAGCTGA ACGTGGACCA CACCACAGAG AACGAGGATG AGCTCTTCCG TCTTTCGCAG 
CTGGGCTTGG ATGCTGGAAA GATCAAGCAG GTGGGGATCA TCTGTGGGCA GGAGAGCACC 
CGGCGGATCG GGGATTACAA GGTTAAATAT GGCTACACGG ACATTGACCT TCTCAGCGCT 
GCCAAGTCCA AACCAATCAT CGCAGAGCCA GAAATCCATG GGGCACAGCC GCTGGATGGG 
GTGACGGGCT TCTTGGTGCT GATGTCGGAG GGGTTGTACA AGGCCCTAGA GGCAGCCCAT 
GGGCCTGGGC AGGCCAACCA GGAGATTGCT GCGATGATTG ACACTGAGTT TGCCAAGCAG 
ACCTCCCTGG ACGCAGTGGC CCAGGCCGTC GTGGACCGGG TGAAGCGCAT CCACAGCGAC 
ACCTTCGCCA GTGGTGGGGA GCGTGCCAGG TTCTGCCCCC GGCACGAGGA CATGACCCTG 
CTAGTGAGGA ACTTTGGCTA CCCGCTGGGC GAAATGAGCC AGCCCACACC GAGCCCAGCC 
CCAGCTGCAG GAGGACGAGT GTACCCTGTG TCTGTGCCAT ACTCCAGCGC CCAGAGCACC 
AGCAAGACCA GCGTGACCCT CTCCCTTGTC ATGCCCTCCC AGGGCCAGAT GGTCAACGGG 
GCTCACAGTG CTTCCACCCT GGACGAAGCC ACCCCCACCC TCACCAACCA AAGCCCGACC 
TTAACCCTGC AGTCCACCAA CACGCACACG CAGAGCAGCA GCTCCAGCTC TGACGGAGGC 
CTCTTCCGCT CCCGGCCCGC CCACTCGCTC CCGCCTGGCG AGGACGGTCG TGTTGAGCCC 
TATGTGGACT TTGCTGAGTT TTACCGCCTC TGGAGCGTGG ACCATGGCGA GCAGAGCGTG 
GTGACAGCAC CGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006107.1
CDS	24..1538
Translation	MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTNQSPTLTLQSTNTHTQSSSSSSDGGLFRSRPAHSLPPGEDGRVEPYVDFAEFYRLWSVDHGEQSVVTAP

Target ORF information:

RefSeq Version	NM_006116.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant alpha, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006116.3

ORF Insert Sequence:

ATGGCGGCGC AGAGGAGGAG CTTGCTGCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC 
CTGCCTCTCT GCCACCTCTC TGGGGTTGGC TCAGCCTCCA ACCGCAGCTA CTCTGCTGAT 
GGCAAGGGCA CTGAGAGCCA CCCGCCAGAG GACAGCTGGC TCAAGTTCAG GAGTGAGAAC 
AACTGCTTCC TGTATGGGGT CTTCAACGGC TATGATGGCA ACCGAGTGAC CAACTTCGTG 
GCCCAGCGGC TGTCCGCAGA GCTCCTGCTG GGCCAGCTGA ATGCCGAGCA CGCCGAGGCC 
GATGTGCGGC GTGTGCTGCT GCAGGCCTTC GATGTGGTGG AGAGGAGCTT CCTGGAGTCC 
ATTGACGACG CCTTGGCTGA GAAGGCAAGC CTCCAGTCGC AATTGCCAGA GGGAGTCCCT 
CAGCACCAGC TGCCTCCTCA GTATCAGAAG ATCCTTGAGA GACTCAAGAC GTTAGAGAGG 
GAAATTTCGG GAGGGGCCAT GGCCGTTGTG GCGGTCCTTC TCAACAACAA GCTCTACGTC 
GCCAATGTCG GTACAAACCG TGCACTTTTA TGCAAATCGA CAGTGGATGG GTTGCAGGTG 
ACACAGCTGA ACGTGGACCA CACCACAGAG AACGAGGATG AGCTCTTCCG TCTTTCGCAG 
CTGGGCTTGG ATGCTGGAAA GATCAAGCAG GTGGGGATCA TCTGTGGGCA GGAGAGCACC 
CGGCGGATCG GGGATTACAA GGTTAAATAT GGCTACACGG ACATTGACCT TCTCAGCGCT 
GCCAAGTCCA AACCAATCAT CGCAGAGCCA GAAATCCATG GGGCACAGCC GCTGGATGGG 
GTGACGGGCT TCTTGGTGCT GATGTCGGAG GGGTTGTACA AGGCCCTAGA GGCAGCCCAT 
GGGCCTGGGC AGGCCAACCA GGAGATTGCT GCGATGATTG ACACTGAGTT TGCCAAGCAG 
ACCTCCCTGG ACGCAGTGGC CCAGGCCGTC GTGGACCGGG TGAAGCGCAT CCACAGCGAC 
ACCTTCGCCA GTGGTGGGGA GCGTGCCAGG TTCTGCCCCC GGCACGAGGA CATGACCCTG 
CTAGTGAGGA ACTTTGGCTA CCCGCTGGGC GAAATGAGCC AGCCCACACC GAGCCCAGCC 
CCAGCTGCAG GAGGACGAGT GTACCCTGTG TCTGTGCCAT ACTCCAGCGC CCAGAGCACC 
AGCAAGACCA GCGTGACCCT CTCCCTTGTC ATGCCCTCCC AGGGCCAGAT GGTCAACGGG 
GCTCACAGTG CTTCCACCCT GGACGAAGCC ACCCCCACCC TCACCAACCA AAGCCCGACC 
TTAACCCTGC AGTCCACCAA CACGCACACG CAGAGCAGCA GCTCCAGCTC TGACGGAGGC 
CTCTTCCGCT CCCGGCCCGC CCACTCGCTC CCGCCTGGCG AGGACGGTCG TGTTGAGCCC 
TATGTGGACT TTGCTGAGTT TTACCGCCTC TGGAGCGTGG ACCATGGCGA GCAGAGCGTG 
GTGACAGCAC CGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TAB1 ( NM_153497.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_705717.1 Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant beta, mRNA.

Price & Availability↑

CloneID	OHu17802
Clone ID Related Accession (Same CDS sequence)	NM_153497.2 , NM_153497.3
Accession Version	NM_153497.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform beta
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC050554.1, AF425640.1 and AI827837.1. This sequence is a reference standard in the RefSeqGene project. On May 27, 2004 this sequence version replaced NM_153497.1. Transcript Variant: This variant (beta) uses an alternate exon at the 3' end compared to variant 1, which includes a part of the coding region. The resulting isoform (beta) has a distinct and shorter C-terminus, as compared to isoform alpha. The beta isoform can interact with and activate MAPK14/p38alpha, but it does not bind or activate MAP3K7/TAK1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF425640.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGC AGAGGAGGAG CTTGCTGCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC 
CTGCCTCTCT GCCACCTCTC TGGGGTTGGC TCAGCCTCCA ACCGCAGCTA CTCTGCTGAT 
GGCAAGGGCA CTGAGAGCCA CCCGCCAGAG GACAGCTGGC TCAAGTTCAG GAGTGAGAAC 
AACTGCTTCC TGTATGGGGT CTTCAACGGC TATGATGGCA ACCGAGTGAC CAACTTCGTG 
GCCCAGCGGC TGTCCGCAGA GCTCCTGCTG GGCCAGCTGA ATGCCGAGCA CGCCGAGGCC 
GATGTGCGGC GTGTGCTGCT GCAGGCCTTC GATGTGGTGG AGAGGAGCTT CCTGGAGTCC 
ATTGACGACG CCTTGGCTGA GAAGGCAAGC CTCCAGTCGC AATTGCCAGA GGGAGTCCCT 
CAGCACCAGC TGCCTCCTCA GTATCAGAAG ATCCTTGAGA GACTCAAGAC GTTAGAGAGG 
GAAATTTCGG GAGGGGCCAT GGCCGTTGTG GCGGTCCTTC TCAACAACAA GCTCTACGTC 
GCCAATGTCG GTACAAACCG TGCACTTTTA TGCAAATCGA CAGTGGATGG GTTGCAGGTG 
ACACAGCTGA ACGTGGACCA CACCACAGAG AACGAGGATG AGCTCTTCCG TCTTTCGCAG 
CTGGGCTTGG ATGCTGGAAA GATCAAGCAG GTGGGGATCA TCTGTGGGCA GGAGAGCACC 
CGGCGGATCG GGGATTACAA GGTTAAATAT GGCTACACGG ACATTGACCT TCTCAGCGCT 
GCCAAGTCCA AACCAATCAT CGCAGAGCCA GAAATCCATG GGGCACAGCC GCTGGATGGG 
GTGACGGGCT TCTTGGTGCT GATGTCGGAG GGGTTGTACA AGGCCCTAGA GGCAGCCCAT 
GGGCCTGGGC AGGCCAACCA GGAGATTGCT GCGATGATTG ACACTGAGTT TGCCAAGCAG 
ACCTCCCTGG ACGCAGTGGC CCAGGCCGTC GTGGACCGGG TGAAGCGCAT CCACAGCGAC 
ACCTTCGCCA GTGGTGGGGA GCGTGCCAGG TTCTGCCCCC GGCACGAGGA CATGACCCTG 
CTAGTGAGGA ACTTTGGCTA CCCGCTGGGC GAAATGAGCC AGCCCACACC GAGCCCAGCC 
CCAGCTGCAG GAGGACGAGT GTACCCTGTG TCTGTGCCAT ACTCCAGCGC CCAGAGCACC 
AGCAAGACCA GCGTGACCCT CTCCCTTGTC ATGCCCTCCC AGGGCCAGAT GGTCAACGGG 
GCTCACAGTG CTTCCACCCT GGACGAAGCC ACCCCCACCC TCACCAAAGA CCCTTCCAGG 
CCTGCAAGCG ATTTGACAGC CATCCCTCAG TGCCAACTAA ACCTCCTGGG CAGCCTGACC 
CCAGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_705717.1
CDS	50..1438
Translation	MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTKDPSRPASDLTAIPQCQLNLLGSLTPG

Target ORF information:

RefSeq Version	NM_153497.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant beta, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153497.2

ORF Insert Sequence:

ATGGCGGCGC AGAGGAGGAG CTTGCTGCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC 
CTGCCTCTCT GCCACCTCTC TGGGGTTGGC TCAGCCTCCA ACCGCAGCTA CTCTGCTGAT 
GGCAAGGGCA CTGAGAGCCA CCCGCCAGAG GACAGCTGGC TCAAGTTCAG GAGTGAGAAC 
AACTGCTTCC TGTATGGGGT CTTCAACGGC TATGATGGCA ACCGAGTGAC CAACTTCGTG 
GCCCAGCGGC TGTCCGCAGA GCTCCTGCTG GGCCAGCTGA ATGCCGAGCA CGCCGAGGCC 
GATGTGCGGC GTGTGCTGCT GCAGGCCTTC GATGTGGTGG AGAGGAGCTT CCTGGAGTCC 
ATTGACGACG CCTTGGCTGA GAAGGCAAGC CTCCAGTCGC AATTGCCAGA GGGAGTCCCT 
CAGCACCAGC TGCCTCCTCA GTATCAGAAG ATCCTTGAGA GACTCAAGAC GTTAGAGAGG 
GAAATTTCGG GAGGGGCCAT GGCCGTTGTG GCGGTCCTTC TCAACAACAA GCTCTACGTC 
GCCAATGTCG GTACAAACCG TGCACTTTTA TGCAAATCGA CAGTGGATGG GTTGCAGGTG 
ACACAGCTGA ACGTGGACCA CACCACAGAG AACGAGGATG AGCTCTTCCG TCTTTCGCAG 
CTGGGCTTGG ATGCTGGAAA GATCAAGCAG GTGGGGATCA TCTGTGGGCA GGAGAGCACC 
CGGCGGATCG GGGATTACAA GGTTAAATAT GGCTACACGG ACATTGACCT TCTCAGCGCT 
GCCAAGTCCA AACCAATCAT CGCAGAGCCA GAAATCCATG GGGCACAGCC GCTGGATGGG 
GTGACGGGCT TCTTGGTGCT GATGTCGGAG GGGTTGTACA AGGCCCTAGA GGCAGCCCAT 
GGGCCTGGGC AGGCCAACCA GGAGATTGCT GCGATGATTG ACACTGAGTT TGCCAAGCAG 
ACCTCCCTGG ACGCAGTGGC CCAGGCCGTC GTGGACCGGG TGAAGCGCAT CCACAGCGAC 
ACCTTCGCCA GTGGTGGGGA GCGTGCCAGG TTCTGCCCCC GGCACGAGGA CATGACCCTG 
CTAGTGAGGA ACTTTGGCTA CCCGCTGGGC GAAATGAGCC AGCCCACACC GAGCCCAGCC 
CCAGCTGCAG GAGGACGAGT GTACCCTGTG TCTGTGCCAT ACTCCAGCGC CCAGAGCACC 
AGCAAGACCA GCGTGACCCT CTCCCTTGTC ATGCCCTCCC AGGGCCAGAT GGTCAACGGG 
GCTCACAGTG CTTCCACCCT GGACGAAGCC ACCCCCACCC TCACCAAAGA CCCTTCCAGG 
CCTGCAAGCG ATTTGACAGC CATCCCTCAG TGCCAACTAA ACCTCCTGGG CAGCCTGACC 
CCAGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TAB1 ( NM_153497.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_705717.1 Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant beta, mRNA.

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CloneID	OHu17802
Clone ID Related Accession (Same CDS sequence)	NM_153497.2 , NM_153497.3
Accession Version	NM_153497.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-07
Organism	Homo sapiens(human)
Product	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform beta
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC050554.1, AF425640.1, AI827837.1 and Z83845.14. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_153497.2. Transcript Variant: This variant (beta) uses an alternate exon at the 3' end compared to variant 1, which includes a part of the coding region. The resulting isoform (beta) has a distinct and shorter C-terminus, as compared to isoform alpha. The beta isoform can interact with and activate MAPK14/p38alpha, but it does not bind or activate MAP3K7/TAK1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF425640.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCGC AGAGGAGGAG CTTGCTGCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC 
CTGCCTCTCT GCCACCTCTC TGGGGTTGGC TCAGCCTCCA ACCGCAGCTA CTCTGCTGAT 
GGCAAGGGCA CTGAGAGCCA CCCGCCAGAG GACAGCTGGC TCAAGTTCAG GAGTGAGAAC 
AACTGCTTCC TGTATGGGGT CTTCAACGGC TATGATGGCA ACCGAGTGAC CAACTTCGTG 
GCCCAGCGGC TGTCCGCAGA GCTCCTGCTG GGCCAGCTGA ATGCCGAGCA CGCCGAGGCC 
GATGTGCGGC GTGTGCTGCT GCAGGCCTTC GATGTGGTGG AGAGGAGCTT CCTGGAGTCC 
ATTGACGACG CCTTGGCTGA GAAGGCAAGC CTCCAGTCGC AATTGCCAGA GGGAGTCCCT 
CAGCACCAGC TGCCTCCTCA GTATCAGAAG ATCCTTGAGA GACTCAAGAC GTTAGAGAGG 
GAAATTTCGG GAGGGGCCAT GGCCGTTGTG GCGGTCCTTC TCAACAACAA GCTCTACGTC 
GCCAATGTCG GTACAAACCG TGCACTTTTA TGCAAATCGA CAGTGGATGG GTTGCAGGTG 
ACACAGCTGA ACGTGGACCA CACCACAGAG AACGAGGATG AGCTCTTCCG TCTTTCGCAG 
CTGGGCTTGG ATGCTGGAAA GATCAAGCAG GTGGGGATCA TCTGTGGGCA GGAGAGCACC 
CGGCGGATCG GGGATTACAA GGTTAAATAT GGCTACACGG ACATTGACCT TCTCAGCGCT 
GCCAAGTCCA AACCAATCAT CGCAGAGCCA GAAATCCATG GGGCACAGCC GCTGGATGGG 
GTGACGGGCT TCTTGGTGCT GATGTCGGAG GGGTTGTACA AGGCCCTAGA GGCAGCCCAT 
GGGCCTGGGC AGGCCAACCA GGAGATTGCT GCGATGATTG ACACTGAGTT TGCCAAGCAG 
ACCTCCCTGG ACGCAGTGGC CCAGGCCGTC GTGGACCGGG TGAAGCGCAT CCACAGCGAC 
ACCTTCGCCA GTGGTGGGGA GCGTGCCAGG TTCTGCCCCC GGCACGAGGA CATGACCCTG 
CTAGTGAGGA ACTTTGGCTA CCCGCTGGGC GAAATGAGCC AGCCCACACC GAGCCCAGCC 
CCAGCTGCAG GAGGACGAGT GTACCCTGTG TCTGTGCCAT ACTCCAGCGC CCAGAGCACC 
AGCAAGACCA GCGTGACCCT CTCCCTTGTC ATGCCCTCCC AGGGCCAGAT GGTCAACGGG 
GCTCACAGTG CTTCCACCCT GGACGAAGCC ACCCCCACCC TCACCAAAGA CCCTTCCAGG 
CCTGCAAGCG ATTTGACAGC CATCCCTCAG TGCCAACTAA ACCTCCTGGG CAGCCTGACC 
CCAGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_705717.1
CDS	24..1412
Translation	MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTLDEATPTLTKDPSRPASDLTAIPQCQLNLLGSLTPG

Target ORF information:

RefSeq Version	NM_153497.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1), transcript variant beta, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153497.3

ORF Insert Sequence:

ATGGCGGCGC AGAGGAGGAG CTTGCTGCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC 
CTGCCTCTCT GCCACCTCTC TGGGGTTGGC TCAGCCTCCA ACCGCAGCTA CTCTGCTGAT 
GGCAAGGGCA CTGAGAGCCA CCCGCCAGAG GACAGCTGGC TCAAGTTCAG GAGTGAGAAC 
AACTGCTTCC TGTATGGGGT CTTCAACGGC TATGATGGCA ACCGAGTGAC CAACTTCGTG 
GCCCAGCGGC TGTCCGCAGA GCTCCTGCTG GGCCAGCTGA ATGCCGAGCA CGCCGAGGCC 
GATGTGCGGC GTGTGCTGCT GCAGGCCTTC GATGTGGTGG AGAGGAGCTT CCTGGAGTCC 
ATTGACGACG CCTTGGCTGA GAAGGCAAGC CTCCAGTCGC AATTGCCAGA GGGAGTCCCT 
CAGCACCAGC TGCCTCCTCA GTATCAGAAG ATCCTTGAGA GACTCAAGAC GTTAGAGAGG 
GAAATTTCGG GAGGGGCCAT GGCCGTTGTG GCGGTCCTTC TCAACAACAA GCTCTACGTC 
GCCAATGTCG GTACAAACCG TGCACTTTTA TGCAAATCGA CAGTGGATGG GTTGCAGGTG 
ACACAGCTGA ACGTGGACCA CACCACAGAG AACGAGGATG AGCTCTTCCG TCTTTCGCAG 
CTGGGCTTGG ATGCTGGAAA GATCAAGCAG GTGGGGATCA TCTGTGGGCA GGAGAGCACC 
CGGCGGATCG GGGATTACAA GGTTAAATAT GGCTACACGG ACATTGACCT TCTCAGCGCT 
GCCAAGTCCA AACCAATCAT CGCAGAGCCA GAAATCCATG GGGCACAGCC GCTGGATGGG 
GTGACGGGCT TCTTGGTGCT GATGTCGGAG GGGTTGTACA AGGCCCTAGA GGCAGCCCAT 
GGGCCTGGGC AGGCCAACCA GGAGATTGCT GCGATGATTG ACACTGAGTT TGCCAAGCAG 
ACCTCCCTGG ACGCAGTGGC CCAGGCCGTC GTGGACCGGG TGAAGCGCAT CCACAGCGAC 
ACCTTCGCCA GTGGTGGGGA GCGTGCCAGG TTCTGCCCCC GGCACGAGGA CATGACCCTG 
CTAGTGAGGA ACTTTGGCTA CCCGCTGGGC GAAATGAGCC AGCCCACACC GAGCCCAGCC 
CCAGCTGCAG GAGGACGAGT GTACCCTGTG TCTGTGCCAT ACTCCAGCGC CCAGAGCACC 
AGCAAGACCA GCGTGACCCT CTCCCTTGTC ATGCCCTCCC AGGGCCAGAT GGTCAACGGG 
GCTCACAGTG CTTCCACCCT GGACGAAGCC ACCCCCACCC TCACCAAAGA CCCTTCCAGG 
CCTGCAAGCG ATTTGACAGC CATCCCTCAG TGCCAACTAA ACCTCCTGGG CAGCCTGACC 
CCAGGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

miR?873 inhibits colorectal cancer cell proliferation by targeting TRAF5 and TAB1.
Oncology reports(2018 Jan)
Gong H,Fang L,Li Y,Du J,Zhou B,Wang X,Zhou H,Gao L,Wang K,Zhang J

TAB1-induced auto-activation of p38? mitogen-activated protein kinase is crucially dependent on Threonine 185.
Molecular and cellular biology(2017 Dec)
Thapa D,Nichols C,Bassi R,Martin ED,Verma S,Conte MR,De Santis V,De Nicola GF,Marber MS

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TAB1 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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