Gene Symbol | DLC1 |
Entrez Gene ID | 10395 |
Full Name | DLC1 Rho GTPase activating protein |
Synonyms | ARHGAP7,HP,STARD12,p122-RhoGAP |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]. |
Disorder MIM: | |
Disorder Html: | Colorectal cancer, somatic, 114500 (3) |