Gene Symbol | SAE1 |
Entrez Gene ID | 10055 |
Full Name | SUMO1 activating enzyme subunit 1 |
Synonyms | AOS1,HSPC140,SUA1,UBLE1A |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]. |
Disorder MIM: |