TSPAN18 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	TSPAN18
Entrez Gene ID	395586
Full Name	tetraspanin 18
Synonyms	tetraspanin-18
General protein information	Preferred Names tetraspanin 18 Names tetraspanin-18 neuronal tetraspanin
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_204801.1	NP_990132.1	tetraspanin-18

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TSPAN18	NP_001074389.1
Homo sapiens (human)	TSPAN18	NP_570139.3
Mus musculus (house mouse)	Tspan18	NP_899003.1
Danio rerio (zebrafish)	tspan18a	NP_001002734.1
Pan troglodytes (chimpanzee)	TSPAN18	XP_001159889.2
	TSPAN18	XP_001113570.1
Gallus gallus (chicken)	TSPAN18	NP_990132.1
Canis lupus familiaris (dog)	TSPAN18	XP_005631366.1
Rattus norvegicus (Norway rat)	Tspan18	NP_001101220.1
Danio rerio (zebrafish)	tspan18b	NP_001002439.1
Xenopus tropicalis (tropical clawed frog)	tspan18	NP_001093673.1

Gene Ontology
Bibliography

Related articles in PubMed

Tetraspanin18 is a FoxD3-responsive antagonist of cranial neural crest epithelial-to-mesenchymal transition that maintains cadherin-6B protein.
Fairchild CL, Gammill LS
Journal of cell science126(Pt 6)1464-76(2013 Mar)

Tetraspanins expressed in the embryonic chick nervous system.
Perron JC, Bixby JL
FEBS letters461(1-2)86-90(1999 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these data reveal post-translational regulation of Cad6B protein levels by Tspan18 that must be relieved by a FoxD3-dependent mechanism in order for cranial neural crest cells to migrate.
Title: Tetraspanin18 is a FoxD3-responsive antagonist of cranial neural crest epithelial-to-mesenchymal transition that maintains cadherin-6B protein.

The following TSPAN18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TSPAN18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00947	NM_204801.1 Latest version!	Gallus gallus tetraspanin 18 (TSPAN18), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TSPAN18 ( NM_204801.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990132.1 Gallus gallus tetraspanin 18 (TSPAN18), mRNA.

Price & Availability↑

CloneID	OGa00947
Clone ID Related Accession (Same CDS sequence)	NM_204801.1
Accession Version	NM_204801.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 744bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	tetraspanin-18
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF206661.1. ##Evidence-Data-START## Transcript exon combination :: AF206661.1 [ECO:0000332] ##Evidence-Data-END##

ATGGAGGGAG ACTGTCTGAG CTGCATGAAG TACCTGATGT TTCTTTTCAA TTTTTTTATA 
TTTCTGGGAG GAGCATGCCT GCTTGGAGTT GGGATCTGGG TCATCGTGGA TCCAACTGGT 
TTTCGAGAGA TCGTGGCTGC CAACCCTCTG CTCTTCACAG GAGCATACAT CATGCTGGCT 
ATGGGAGCAA TGCTCTTTCT GCTGGGTTTC CTTGGCTGTT GCGGTGCCAT CCGTGAGAAC 
AAATGTCTCC TACTTTTTTT CTTCATGTTT ATTTTGTTAA TCTTCCTGGC GGAGCTTTCA 
GCTGCAATCC TGGCTTTTAT CTTCAGAGAA AATCTGACGA GAGAGTTTTT CACCAAGGAG 
CTGAAGAAGC ATTATGTGAG GAACAATGAC ACGCATGTCT TCTCCTCCAC CTGGAACTCT 
GTTATGATCA CATTTGCCTG CTGTGGAGTG AACGGACCAG AAGATTTTGA AGCTGTCCCT 
CCACTTTCAC ACTTGCCTTT GGAAGAGACT ACACCAGAGG CTTGTTGCCA GCGAAACGTC 
CAGAGCCGGG AAGGGATGTT TGTTAACAGG AAAGCCTGCC TCGAAGGCGA TGAGAGATTT 
CAGAACCGGC AGGGCTGCTA CACTGTGATC CTGAACTCCT TTGAGACCTA CGTGTACCTT 
GCAGGAGCCC TGGCCATTGG AGTGCTGGCC ATTGAGCTGT TCGCCATGAT TTTTGCCATG 
TGTCTCTTCC GAGGGATCCA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990132.1
CDS	153..896
Translation	MEGDCLSCMKYLMFLFNFFIFLGGACLLGVGIWVIVDPTGFREIVAANPLLFTGAYIMLAMGAMLFLLGFLGCCGAIRENKCLLLFFFMFILLIFLAELSAAILAFIFRENLTREFFTKELKKHYVRNNDTHVFSSTWNSVMITFACCGVNGPEDFEAVPPLSHLPLEETTPEACCQRNVQSREGMFVNRKACLEGDERFQNRQGCYTVILNSFETYVYLAGALAIGVLAIELFAMIFAMCLFRGIQ

Target ORF information:

RefSeq Version	NM_204801.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus tetraspanin 18 (TSPAN18), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204801.1

ORF Insert Sequence:

ATGGAGGGAG ACTGTCTGAG CTGCATGAAG TACCTGATGT TTCTTTTCAA TTTTTTTATA 
TTTCTGGGAG GAGCATGCCT GCTTGGAGTT GGGATCTGGG TCATCGTGGA TCCAACTGGT 
TTTCGAGAGA TCGTGGCTGC CAACCCTCTG CTCTTCACAG GAGCATACAT CATGCTGGCT 
ATGGGAGCAA TGCTCTTTCT GCTGGGTTTC CTTGGCTGTT GCGGTGCCAT CCGTGAGAAC 
AAATGTCTCC TACTTTTTTT CTTCATGTTT ATTTTGTTAA TCTTCCTGGC GGAGCTTTCA 
GCTGCAATCC TGGCTTTTAT CTTCAGAGAA AATCTGACGA GAGAGTTTTT CACCAAGGAG 
CTGAAGAAGC ATTATGTGAG GAACAATGAC ACGCATGTCT TCTCCTCCAC CTGGAACTCT 
GTTATGATCA CATTTGCCTG CTGTGGAGTG AACGGACCAG AAGATTTTGA AGCTGTCCCT 
CCACTTTCAC ACTTGCCTTT GGAAGAGACT ACACCAGAGG CTTGTTGCCA GCGAAACGTC 
CAGAGCCGGG AAGGGATGTT TGTTAACAGG AAAGCCTGCC TCGAAGGCGA TGAGAGATTT 
CAGAACCGGC AGGGCTGCTA CACTGTGATC CTGAACTCCT TTGAGACCTA CGTGTACCTT 
GCAGGAGCCC TGGCCATTGG AGTGCTGGCC ATTGAGCTGT TCGCCATGAT TTTTGCCATG 
TGTCTCTTCC GAGGGATCCA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tetraspanin18 is a FoxD3-responsive antagonist of cranial neural crest epithelial-to-mesenchymal transition that maintains cadherin-6B protein.
Journal of cell science126(Pt 6)1464-76(2013 Mar)
Fairchild CL,Gammill LS

Tetraspanins expressed in the embryonic chick nervous system.
FEBS letters461(1-2)86-90(1999 Nov)
Perron JC,Bixby JL