gRNAs
The following BRCA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BRCA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OGa25993 | |
| Clone ID Related Accession (Same CDS sequence) | XM_025150482.1 , NM_204276.2 | |
| Accession Version | NM_204276.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 10194bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-01-19 | |
| Organism | Gallus gallus(chicken) | |
| Product | breast cancer type 2 susceptibility protein | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AADN05000588.1. On May 3, 2007 this sequence version replaced NM_204276.1. Sequence Note: This RefSeq record was derived from genomic sequence to make the sequence consistent with the reference genome assembly but is supported by transcript alignments and orthologous data. ##Evidence-Data-START## CDS exon combination :: AB066374.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA2201357, SAMEA2201358 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCTTACA AATCTGGGAA AAGACCTACT TTCTTTGAAG TATTTAAGGC GCATTGTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_989607.2 |
| CDS | 139..10332 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_204276.2 |
1 | ATGGCTTACA AATCTGGGAA AAGACCTACT TTCTTTGAAG TATTTAAGGC GCATTGTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OGa25993 | |
| Clone ID Related Accession (Same CDS sequence) | XM_025150482.1 , NM_204276.2 | |
| Accession Version | XM_025150482.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 10194bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-16 | |
| Organism | Gallus gallus(chicken) | |
| Product | breast cancer type 2 susceptibility protein isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006088.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCTTACA AATCTGGGAA AAGACCTACT TTCTTTGAAG TATTTAAGGC GCATTGTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_025006250.1 |
| CDS | 194..10387 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_025150482.1 |
1 | ATGGCTTACA AATCTGGGAA AAGACCTACT TTCTTTGAAG TATTTAAGGC GCATTGTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OGa30924 | |
| Clone ID Related Accession (Same CDS sequence) | XM_015277493.1 | |
| Accession Version | XM_015277493.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 9363bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-01-03 | |
| Organism | Gallus gallus(chicken) | |
| Product | breast cancer type 2 susceptibility protein isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_455760.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Gallus gallus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCTTACA AATCTGGGAA AAGACCTACT TTCTTTGAAG TATTTAAGGC GCATTGTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_015132979.1 |
| CDS | 25..9387 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_015277493.1 |
1 | ATGGCTTACA AATCTGGGAA AAGACCTACT TTCTTTGAAG TATTTAAGGC GCATTGTAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. |
The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry. |
Functional interplay between BRCA2/FancD1 and FancC in DNA repair. |
Phenotypic effects of heterozygosity for a BRCA2 mutation. |
Structural analysis of the chicken BRCA2 gene facilitates identification of functional domains and disease causing mutations. |
