Gene Symbol | DHFR |
Entrez Gene ID | 508809 |
Full Name | dihydrofolate reductase |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » DHFR cDNA ORF clone
Gene Symbol | DHFR |
Entrez Gene ID | 508809 |
Full Name | dihydrofolate reductase |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_001077883.1 | NP_001071351.1 | dihydrofolate reductase |
Homo sapiens (human) | DHFR | NP_000782.1 |
Danio rerio (zebrafish) | dhfr | NP_571850.1 |
DHFR | XP_001099963.2 | |
Caenorhabditis elegans (roundworm) | dhfr-1 | NP_492364.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100486206 | XP_002942406.1 |
Pan troglodytes (chimpanzee) | DHFR | XP_001134992.1 |
Gallus gallus (chicken) | DHFR | NP_001006584.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010278 | XP_319471.3 |
Schizosaccharomyces pombe (fission yeast) | dfr1 | NP_588353.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_10204 | XP_003713835.1 |
Canis lupus familiaris (dog) | DHFR | XP_003432528.1 |
Bos taurus (cattle) | DHFR | NP_001071351.1 |
Mus musculus (house mouse) | Dhfr | NP_034179.1 |
Rattus norvegicus (Norway rat) | Dhfr | NP_569084.1 |
Drosophila melanogaster (fruit fly) | Dhfr | NP_732147.1 |
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase.
Chalupsky K, Cai H
Proceedings of the National Academy of Sciences of the United States of America102(25)9056-61(2005 Jun)
Structure of dihydrofolate reductase: primary sequence of the bovine liver enzyme.
Lai PH, Pan YC, Gleisner JM, Peterson DL, Williams KR, Blakley RL
Biochemistry21(14)3284-94(1982 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Hydrogen peroxide down regulates expression in response to angiotensin Ii and underlies endothelial nitric oxide synthase dysfunction.
Title: Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase.
The following DHFR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DHFR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa43877 | |
Clone ID Related Accession (Same CDS sequence) | NM_001077883.1 | |
Accession Version | NM_001077883.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 564bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | dihydrofolate reductase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC114162.1. On Nov 21, 2006 this sequence version replaced XM_585641.2. ##Evidence-Data-START## Transcript exon combination :: BC114162.1, DV919469.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGTTCGTC CACTAAACTG CATCGTTGCT GTGTCCCAGA ACATGGGTAT CGGCAAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001071351.1 |
CDS | 78..641 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001077883.1 |
1 | ATGGTTCGTC CACTAAACTG CATCGTTGCT GTGTCCCAGA ACATGGGTAT CGGCAAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A whole-genome assembly of the domestic cow, Bos taurus. |
Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase. |
Structure of dihydrofolate reductase: primary sequence of the bovine liver enzyme. |