Gene Symbol | RNASE1 |
Entrez Gene ID | 282340 |
Full Name | ribonuclease, RNase A family, 1 (pancreatic) |
Synonyms | RNS1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » RNASE1 cDNA ORF clone
Gene Symbol | RNASE1 |
Entrez Gene ID | 282340 |
Full Name | ribonuclease, RNase A family, 1 (pancreatic) |
Synonyms | RNS1 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005211462.2 | XP_005211519.1 | ribonuclease pancreatic isoform X1 |
NM_001014386.4 | NP_001014408.2 | ribonuclease pancreatic precursor |
Rattus norvegicus (Norway rat) | Rnase1l1 | NP_001013250.1 |
Canis lupus familiaris (dog) | LOC475395 | XP_003432057.1 |
Bos taurus (cattle) | RNASE1 | NP_001014408.2 |
Pan troglodytes (chimpanzee) | RNASE1 | NP_001009108.2 |
RNASE1 | NP_001038203.1 | |
Bos taurus (cattle) | BRB | NP_776316.1 |
Mus musculus (house mouse) | Rnase1 | NP_035401.2 |
Rattus norvegicus (Norway rat) | Rnase1 | NP_001025075.1 |
Homo sapiens (human) | RNASE1 | NP_937878.1 |
Rattus norvegicus (Norway rat) | Rnase1l2 | NP_001020287.1 |
Thermodynamic analysis of osmolyte effect on thermal stability of ribonuclease A in terms of water activity.
Miyawaki O, Dozen M, Nomura K
Biophysical chemistry18519-24(2014 Jan)
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice.
Sun X, Wiedeman A, Agrawal N, Teal TH, Tanaka L, Hudkins KL, Alpers CE, Bolland S, Buechler MB, Hamerman JA, Ledbetter JA, Liggitt D, Elkon KB
Journal of immunology (Baltimore, Md. : 1950)190(6)2536-43(2013 Mar)
Protein prosthesis: ?-peptides as reverse-turn surrogates.
Arnold U, Huck BR, Gellman SH, Raines RT
Protein science : a publication of the Protein Society22(3)274-9(2013 Mar)
Urea's effect on the ribonuclease A catalytic efficiency: a kinetic, 1H NMR and molecular orbital study.
Almarza J, Rinc?n L, Bahsas A, Pinto MA, Brito F
The protein journal32(2)118-25(2013 Feb)
Effect of D-amino acids on the functional activity and conformational stability of ribonuclease-A.
Shahjee HM, Rishi V, Ahmad F
Indian journal of biochemistry & biophysics39(6)368-76(2002 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Thermal unfolding of ribonuclease A (RNase) was analyzed in various osmolyte solutions of glycine, proline, sarcosine, N,N-dimethylglycine, betaine, myo-inositol, taurine, and trimethylamine-N-oxide (TMAO).
Title: Thermodynamic analysis of osmolyte effect on thermal stability of ribonuclease A in terms of water activity.
Overexpression of bovine RNase in Toll-like receptor (TLR)7 transgenic mice results in reduction in splenomegaly, reduced numbers of activated B and T cells, fewer immune deposits in the kidney, reduced liver inflammation, and increased survival.
Title: Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice.
investigation of structure/stability of native pancreatic RNase A compared to specific analogs: Results suggest that a reverse turn (Asn113-Pro114) exhibits great control over unfolding, conformational stability, and enzymatic activity of RNase A.
Title: Protein prosthesis: ?-peptides as reverse-turn surrogates.
The initials steps of the molecular mechanism of Urea-RNase A interaction passes through the establishment of a three center four electron adduct.
Title: Urea's effect on the ribonuclease A catalytic efficiency: a kinetic, 1H NMR and molecular orbital study.
Effect of D-amino acids on the functional activity and conformational stability of ribonuclease-A
Title: Effect of D-amino acids on the functional activity and conformational stability of ribonuclease-A.
The following RNASE1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RNASE1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa01367 | |
Clone ID Related Accession (Same CDS sequence) | XM_005211462.2 , NM_001014386.4 | |
Accession Version | NM_001014386.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Bos taurus(cattle) | |
Product | ribonuclease pancreatic precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC149636.1. On Aug 30, 2012 this sequence version replaced NM_001014386.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC149636.1, EV644235.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTCTGA AGTCCCTGGT CCTGTTGTCG CTGTTGGTCC TGGTGCTGCT GCTGGTGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001014408.2 |
CDS | 71..523 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001014386.4 |
1 | ATGGCTCTGA AGTCCCTGGT CCTGTTGTCG CTGTTGGTCC TGGTGCTGCT GCTGGTGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa01367 | |
Clone ID Related Accession (Same CDS sequence) | XM_005211462.2 , NM_001014386.4 | |
Accession Version | XM_005211462.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 453bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | ribonuclease pancreatic isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037337.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 30, 2014 this sequence version replaced XM_005211462.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCTGA AGTCCCTGGT CCTGTTGTCG CTGTTGGTCC TGGTGCTGCT GCTGGTGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005211519.1 |
CDS | 136..588 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005211462.2 |
1 | ATGGCTCTGA AGTCCCTGGT CCTGTTGTCG CTGTTGGTCC TGGTGCTGCT GCTGGTGCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Thermodynamic analysis of osmolyte effect on thermal stability of ribonuclease A in terms of water activity. |
Increased ribonuclease expression reduces inflammation and prolongs survival in TLR7 transgenic mice. |
Protein prosthesis: ?-peptides as reverse-turn surrogates. |
Urea's effect on the ribonuclease A catalytic efficiency: a kinetic, 1H NMR and molecular orbital study. |
Effect of D-amino acids on the functional activity and conformational stability of ribonuclease-A. |