DSG1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	DSG1
Entrez Gene ID	281131
Full Name	desmoglein 1
General protein information	Preferred Names desmoglein 1 Names desmoglein-1 DG1 DGI desmosomal glycoprotein 1 pemphigus foliaceus antigen
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174045.1	NP_776470.1	desmoglein-1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Dsg1b	NP_859010.1
Pan troglodytes (chimpanzee)	DSG1	XP_523899.2
Rattus norvegicus (Norway rat)	Dsg1	XP_214616.5
Homo sapiens (human)	DSG1	NP_001933.2
Canis lupus familiaris (dog)	DSG1	NP_001002939.1
	DSG1	XP_001098203.1
Bos taurus (cattle)	DSG1	NP_776470.1
Mus musculus (house mouse)	Dsg1a	NP_034209.2

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Interactions of the cytoplasmic domain of the desmosomal cadherin Dsg1 with plakoglobin.
Mathur M, Goodwin L, Cowin P
The Journal of biological chemistry269(19)14075-80(1994 May)

Structure of DSG1, the bovine desmosomal cadherin gene encoding the pemphigus foliaceus antigen. Evidence of polymorphism.
Puttagunta S, Mathur M, Cowin P
The Journal of biological chemistry269(3)1949-55(1994 Jan)

Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene.
Koch PJ, Goldschmidt MD, Walsh MJ, Zimbelmann R, Franke WW
European journal of cell biology55(2)200-8(1991 Aug)

Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules.
Koch PJ, Walsh MJ, Schmelz M, Goldschmidt MD, Zimbelmann R, Franke WW
European journal of cell biology53(1)1-12(1990 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DSG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DSG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa43362	NM_174045.1 Latest version!	Bos taurus desmoglein 1 (DSG1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DSG1 ( NM_174045.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776470.1 Bos taurus desmoglein 1 (DSG1), mRNA.

Price & Availability↑

CloneID	OBa43362
Clone ID Related Accession (Same CDS sequence)	NM_174045.1
Accession Version	NM_174045.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3132bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Bos taurus(cattle)
Product	desmoglein-1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X58466.1. ##Evidence-Data-START## Transcript exon combination :: X58466.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145467 [ECO:0000348] ##Evidence-Data-END##

ATGAACTGGC CCTTCTTCAG AGCAGCTGTG GTGCTGTTCA TTTTCCTGGT GGTGCTGGAA 
GTTAACAGTG ACTTTAGAAT CCAGGTCAGG GATTATAACA CTAAAAATGG CACCATCAAG 
TGGCACTCCC TCAGGAGGCA AAAGCGCGAG TGGATCAAGT TTGCTGCAGC CTGCCGGGAA 
GGGGAGGACA ACTCAAAGAG GAACCCGATC GCCAAAATTC ACTCAGATTG CGCTGCAAAC 
CAGCAAGTTA CATACCGCAT CTCTGGAGTA GGAATCGATC AGCCACCTTA TGGAATCTTT 
GTTATTAATC AAAAAACTGG TGAAATTAAT ATAACATCCA TAGTTGATCG AGAGGTCACC 
CCTTTTTTCA TTATCTATTG CCGGGCTCTG AATTCACTGG GCCAAGATTT AGAGAAACCT 
CTTGAGCTTA GAGTCAGGGT TTTGGATATA AATGACAACC CTCCAGTATT TTCTATGTCT 
ACTTTTGTAG GAGAAATAGA AGAAAATTCT AACGCAAATA CACTGGTGAT GGTACTCAAT 
GCTACTGATG CAGATGAACC AAATAATTTG AACTCAAAAA TAGCCTTCAA GATCATAAGA 
CAAGAACCTT CAGATTCACC GATGTTTATT ATCAACAGAT ACACTGGAGA AATTCGAACA 
ATGAATAATT TTCTAGACAG AGAGCAATAT GGCCAGTACT CTCTAGCTGT AAGAGGCTCA 
GACCGAGATG GTGGGGCAGA TGGTATGTCA GCAGAGTGTG AATGCAACAT TAAAATCCTC 
GATGTCAATG ATAACATTCC ATACATGGAA CTGCCAACAC AATCCATAAG CATTGAAGAA 
AATTCTCTGA ATTCAAATTT GCTCCAGATT AGAGTAATAG ATTTGGATGA GGAGTTCTCA 
GCTAACTGGA TGGCAGTCAT TTTCTTCATC TCCGGAAATG AGGGGAATTG GTTTGAAATA 
GAAATGAATG AAAGAACAAA TGTGGGAACT TTAAAGGTTG TTAAGCCCCT AGATTTTGAA 
GCTATGAATA ATCTGCAACT TAGTCTTGGT GTTAGAAATA AAGCTGAATT TCATCAATCA 
ATTATGTCTC AATATAAACT CACAGCAACT GCAATCTCTG TGACCGTGTT AAACGTAGTT 
GAAGGCTCAG TGTTCCGTCC AGGTTCAAAG ACATTTGTAG TAAATAGTAA TATGGGACAA 
AACTATAAAA TAGGAGAGTA TGTAGCTTGG GATCTCGACG CAAATCGGCC TTCAACAACT 
GTTAGATACG TAATGGGAAG AAATCCAACT GACTTGCTCG CTATTGACTC AAAAACAGCC 
ATAATTACTT TGAGAAATAA AGTTACTATG GAACAATACA AAATACTTGG GGGAAAATAC 
CAAGGAACAA TTCTATCTAT AGATGATGCT CTTCAAAGAA CTTGTACTGG TACAATTGTT 
ATTAACCTTG AAAATGGTGG CTGGAAAACT GAACGTCCAA ATGTAAATGG AAGTACTACC 
TCTGCATATG GCCTTACTTC CGGAGGTGTT ACCACTAATG GCTACACAAC TGGTGGTGGT 
GTTGGCACAG TTACTTTTGC TGTTGGCACA AATGGTTATG GTGTAGGAAC TGGTGTTTAT 
CAGCCACTAA GAGATAATGT ACATTTTGGT CCTGCTGGCA TTGGACTACT CATCATGGGA 
TTCTTGGTCC TAGGATTGGT CCCCTTCTTG CTGATGTGCT GTGACTGTGG AGGCGCCCCT 
GGCGGCGGGG CTGCCTTTGA GCCTGTTCCT GAATGTTCCG ATGGAGCAAT TCACTCGTGG 
GCAGTGGAAG GTGCACAGGC CGATCCTGGG GTTCTGGCCA ATAGTGCTGT ACCATGCATA 
CCAGTCACTA ATGCAAATGT AATTGAGTAT GTTGACAACT CAGGAGTTTA CACAAATGAG 
TATGGTGCCA GAGAAATGCA AGATCTGGGA GGAGGAGAAA GAACGACAGG ATTTGAACTA 
ACAGATGGAG TTAAAATGTC AGGAGGACCT GAGATATGTC AAGAATATCC TGGAACACTA 
AGAAGAAATT CTATGAGGGA ATGTAGAGAA GGAGGGCTGA ATATGAACTT CATGGAAAGT 
TACTTCTGCC AGAAAGCATA TGCTTATGCG GATGAAGACG AAGGACGCCC ATCCAATGAC 
TGTCTGCTAA TCTACGATAT TGAGGGTGCA GGCTCCCCTG CGGGCTCTGT GGGCTGTTGT 
AGCTTCATTG GAGAAGACTT GGATGACAGC TTCTTGGATA CACTGGGGCC GAAGTTTAAG 
AAGTTGGCAG ACATCAGCCT GGGAAAAGAC GTTGAACCAT TTCCAGACTC TGATCCCTCT 
TGGCCACCTA AGAGCACTGA GCCGGTCTGC CCTCCGCAGG GAACAGAGCC CACTGGTGGT 
GGACACCCAC CCATCTCCCC ACGTTTCGGC ACCACCACCG TCATCTCTGA GAACACCTAC 
CCCTCGGGAC CTGGGGTACA GCACCCTACG CCGATTCCTG ATCCTCTGGG CTATGGTAAT 
GTCACCGTGA CCGAGTCTTA CACCTCCTCG GGCACTCTGA AGCCCTCTGT CCACATTCAC 
GATAACCGAC ACGCATCAAA CGTGGTGGTG ACAGAGCGGG TAGTCGGTCC AATCTCCGGT 
GCCGACTTGC AGGGGATGCT AGAGATGCCT GACTTGAGAG ACGGGTCAAA CGTGATAGTG 
ACAGAAAGGG TAATAGCACC AAGTTCAAGT CTGCCCACCA CTCTGACCAT CCCTGATCCT 
AGGCAGTCTT CCAATGTAGT AGTGACGGAA AGAGTGATCC AGCCAACTTC CGGCATAGTG 
GGCAATCTGA GCATGCACCC TGAGTTATCA AACACCCACA ACGTGATTGT GACGGAGAGG 
GTAGTTTCCG GCTCCGGCAT CACGGGCAGC AGCAGCCTGC TGGGCAGTGC AGGTGGAGGA 
AGTGGTGGTG GCATCGGGCT GGGCAGCCTA GGAGGTGGCG GGGGCCTGAG TAGCAGCCTA 
GGGGGCGCAG CCACCATCGG CCACTTGAGG GGTTCCGCTG AGCATCACTT TAGCAACACC 
CTCGGTTCCG CCTCCCCTAC CACAACCCGG AGTCGAATCA CAAAGTACAG TACAGTTCAA 
TATACCAAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776470.1
CDS	101..3232
Translation	MNWPFFRAAVVLFIFLVVLEVNSDFRIQVRDYNTKNGTIKWHSLRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSLGQDLEKPLELRVRVLDINDNPPVFSMSTFVGEIEENSNANTLVMVLNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRYTGEIRTMNNFLDREQYGQYSLAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMELPTQSISIEENSLNSNLLQIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDFEAMNNLQLSLGVRNKAEFHQSIMSQYKLTATAISVTVLNVVEGSVFRPGSKTFVVNSNMGQNYKIGEYVAWDLDANRPSTTVRYVMGRNPTDLLAIDSKTAIITLRNKVTMEQYKILGGKYQGTILSIDDALQRTCTGTIVINLENGGWKTERPNVNGSTTSAYGLTSGGVTTNGYTTGGGVGTVTFAVGTNGYGVGTGVYQPLRDNVHFGPAGIGLLIMGFLVLGLVPFLLMCCDCGGAPGGGAAFEPVPECSDGAIHSWAVEGAQADPGVLANSAVPCIPVTNANVIEYVDNSGVYTNEYGAREMQDLGGGERTTGFELTDGVKMSGGPEICQEYPGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGAGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKDVEPFPDSDPSWPPKSTEPVCPPQGTEPTGGGHPPISPRFGTTTVISENTYPSGPGVQHPTPIPDPLGYGNVTVTESYTSSGTLKPSVHIHDNRHASNVVVTERVVGPISGADLQGMLEMPDLRDGSNVIVTERVIAPSSSLPTTLTIPDPRQSSNVVVTERVIQPTSGIVGNLSMHPELSNTHNVIVTERVVSGSGITGSSSLLGSAGGGSGGGIGLGSLGGGGGLSSSLGGAATIGHLRGSAEHHFSNTLGSASPTTTRSRITKYSTVQYTK

Target ORF information:

RefSeq Version	NM_174045.1
Organism	Bos taurus(cattle)
Definition	Bos taurus desmoglein 1 (DSG1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174045.1

ORF Insert Sequence:

ATGAACTGGC CCTTCTTCAG AGCAGCTGTG GTGCTGTTCA TTTTCCTGGT GGTGCTGGAA 
GTTAACAGTG ACTTTAGAAT CCAGGTCAGG GATTATAACA CTAAAAATGG CACCATCAAG 
TGGCACTCCC TCAGGAGGCA AAAGCGCGAG TGGATCAAGT TTGCTGCAGC CTGCCGGGAA 
GGGGAGGACA ACTCAAAGAG GAACCCGATC GCCAAAATTC ACTCAGATTG CGCTGCAAAC 
CAGCAAGTTA CATACCGCAT CTCTGGAGTA GGAATCGATC AGCCACCTTA TGGAATCTTT 
GTTATTAATC AAAAAACTGG TGAAATTAAT ATAACATCCA TAGTTGATCG AGAGGTCACC 
CCTTTTTTCA TTATCTATTG CCGGGCTCTG AATTCACTGG GCCAAGATTT AGAGAAACCT 
CTTGAGCTTA GAGTCAGGGT TTTGGATATA AATGACAACC CTCCAGTATT TTCTATGTCT 
ACTTTTGTAG GAGAAATAGA AGAAAATTCT AACGCAAATA CACTGGTGAT GGTACTCAAT 
GCTACTGATG CAGATGAACC AAATAATTTG AACTCAAAAA TAGCCTTCAA GATCATAAGA 
CAAGAACCTT CAGATTCACC GATGTTTATT ATCAACAGAT ACACTGGAGA AATTCGAACA 
ATGAATAATT TTCTAGACAG AGAGCAATAT GGCCAGTACT CTCTAGCTGT AAGAGGCTCA 
GACCGAGATG GTGGGGCAGA TGGTATGTCA GCAGAGTGTG AATGCAACAT TAAAATCCTC 
GATGTCAATG ATAACATTCC ATACATGGAA CTGCCAACAC AATCCATAAG CATTGAAGAA 
AATTCTCTGA ATTCAAATTT GCTCCAGATT AGAGTAATAG ATTTGGATGA GGAGTTCTCA 
GCTAACTGGA TGGCAGTCAT TTTCTTCATC TCCGGAAATG AGGGGAATTG GTTTGAAATA 
GAAATGAATG AAAGAACAAA TGTGGGAACT TTAAAGGTTG TTAAGCCCCT AGATTTTGAA 
GCTATGAATA ATCTGCAACT TAGTCTTGGT GTTAGAAATA AAGCTGAATT TCATCAATCA 
ATTATGTCTC AATATAAACT CACAGCAACT GCAATCTCTG TGACCGTGTT AAACGTAGTT 
GAAGGCTCAG TGTTCCGTCC AGGTTCAAAG ACATTTGTAG TAAATAGTAA TATGGGACAA 
AACTATAAAA TAGGAGAGTA TGTAGCTTGG GATCTCGACG CAAATCGGCC TTCAACAACT 
GTTAGATACG TAATGGGAAG AAATCCAACT GACTTGCTCG CTATTGACTC AAAAACAGCC 
ATAATTACTT TGAGAAATAA AGTTACTATG GAACAATACA AAATACTTGG GGGAAAATAC 
CAAGGAACAA TTCTATCTAT AGATGATGCT CTTCAAAGAA CTTGTACTGG TACAATTGTT 
ATTAACCTTG AAAATGGTGG CTGGAAAACT GAACGTCCAA ATGTAAATGG AAGTACTACC 
TCTGCATATG GCCTTACTTC CGGAGGTGTT ACCACTAATG GCTACACAAC TGGTGGTGGT 
GTTGGCACAG TTACTTTTGC TGTTGGCACA AATGGTTATG GTGTAGGAAC TGGTGTTTAT 
CAGCCACTAA GAGATAATGT ACATTTTGGT CCTGCTGGCA TTGGACTACT CATCATGGGA 
TTCTTGGTCC TAGGATTGGT CCCCTTCTTG CTGATGTGCT GTGACTGTGG AGGCGCCCCT 
GGCGGCGGGG CTGCCTTTGA GCCTGTTCCT GAATGTTCCG ATGGAGCAAT TCACTCGTGG 
GCAGTGGAAG GTGCACAGGC CGATCCTGGG GTTCTGGCCA ATAGTGCTGT ACCATGCATA 
CCAGTCACTA ATGCAAATGT AATTGAGTAT GTTGACAACT CAGGAGTTTA CACAAATGAG 
TATGGTGCCA GAGAAATGCA AGATCTGGGA GGAGGAGAAA GAACGACAGG ATTTGAACTA 
ACAGATGGAG TTAAAATGTC AGGAGGACCT GAGATATGTC AAGAATATCC TGGAACACTA 
AGAAGAAATT CTATGAGGGA ATGTAGAGAA GGAGGGCTGA ATATGAACTT CATGGAAAGT 
TACTTCTGCC AGAAAGCATA TGCTTATGCG GATGAAGACG AAGGACGCCC ATCCAATGAC 
TGTCTGCTAA TCTACGATAT TGAGGGTGCA GGCTCCCCTG CGGGCTCTGT GGGCTGTTGT 
AGCTTCATTG GAGAAGACTT GGATGACAGC TTCTTGGATA CACTGGGGCC GAAGTTTAAG 
AAGTTGGCAG ACATCAGCCT GGGAAAAGAC GTTGAACCAT TTCCAGACTC TGATCCCTCT 
TGGCCACCTA AGAGCACTGA GCCGGTCTGC CCTCCGCAGG GAACAGAGCC CACTGGTGGT 
GGACACCCAC CCATCTCCCC ACGTTTCGGC ACCACCACCG TCATCTCTGA GAACACCTAC 
CCCTCGGGAC CTGGGGTACA GCACCCTACG CCGATTCCTG ATCCTCTGGG CTATGGTAAT 
GTCACCGTGA CCGAGTCTTA CACCTCCTCG GGCACTCTGA AGCCCTCTGT CCACATTCAC 
GATAACCGAC ACGCATCAAA CGTGGTGGTG ACAGAGCGGG TAGTCGGTCC AATCTCCGGT 
GCCGACTTGC AGGGGATGCT AGAGATGCCT GACTTGAGAG ACGGGTCAAA CGTGATAGTG 
ACAGAAAGGG TAATAGCACC AAGTTCAAGT CTGCCCACCA CTCTGACCAT CCCTGATCCT 
AGGCAGTCTT CCAATGTAGT AGTGACGGAA AGAGTGATCC AGCCAACTTC CGGCATAGTG 
GGCAATCTGA GCATGCACCC TGAGTTATCA AACACCCACA ACGTGATTGT GACGGAGAGG 
GTAGTTTCCG GCTCCGGCAT CACGGGCAGC AGCAGCCTGC TGGGCAGTGC AGGTGGAGGA 
AGTGGTGGTG GCATCGGGCT GGGCAGCCTA GGAGGTGGCG GGGGCCTGAG TAGCAGCCTA 
GGGGGCGCAG CCACCATCGG CCACTTGAGG GGTTCCGCTG AGCATCACTT TAGCAACACC 
CTCGGTTCCG CCTCCCCTAC CACAACCCGG AGTCGAATCA CAAAGTACAG TACAGTTCAA 
TATACCAAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Interactions of the cytoplasmic domain of the desmosomal cadherin Dsg1 with plakoglobin.
The Journal of biological chemistry269(19)14075-80(1994 May)
Mathur M,Goodwin L,Cowin P

Structure of DSG1, the bovine desmosomal cadherin gene encoding the pemphigus foliaceus antigen. Evidence of polymorphism.
The Journal of biological chemistry269(3)1949-55(1994 Jan)
Puttagunta S,Mathur M,Cowin P

Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene.
European journal of cell biology55(2)200-8(1991 Aug)
Koch PJ,Goldschmidt MD,Walsh MJ,Zimbelmann R,Franke WW

Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules.
European journal of cell biology53(1)1-12(1990 Oct)
Koch PJ,Walsh MJ,Schmelz M,Goldschmidt MD,Zimbelmann R,Franke WW

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DSG1 cDNA ORF clone, Bos taurus(cattle)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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