Gene Symbol | NIK1 |
Entrez Gene ID | 831457 |
Full Name | NSP-interacting kinase 1 |
Synonyms | AtNIK1,F1N13.140,F1N13_140,NSP-interacting kinase 1 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
ORF » Species Summary » Arabidopsis thaliana » NIK1 cDNA ORF clone
Gene Symbol | NIK1 |
Entrez Gene ID | 831457 |
Full Name | NSP-interacting kinase 1 |
Synonyms | AtNIK1,F1N13.140,F1N13_140,NSP-interacting kinase 1 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
mRNA | Protein | Name |
---|---|---|
NM_121605.3 | NP_197104.1 | NSP-interacting kinase 1 |
Arabidopsis thaliana (thale cress) | NIK1 | NP_197104.1 |
Arabidopsis thaliana (thale cress) | NIK2 | NP_974360.1 |
Oryza sativa (rice) | Os06g0274500 | NP_001057376.1 |
Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.
Tabata S, Kaneko T, Nakamura Y, Kotani H, Kato T, Asamizu E, Miyajima N, Sasamoto S, Kimura T, Hosouchi T, Kawashima K, Kohara M, Matsumoto M, Matsuno A, Muraki A, Nakayama S, Nakazaki N, Naruo K, Okumura S, Shinpo S, Takeuchi C, Wada T, Watanabe A, Yamada M, Yasuda M, Sato S, de la Bastide M, Huang E, Spiegel L, Gnoj L, O'Shaughnessy A, Preston R, Habermann K, Murray J, Johnson D, Rohlfing T, Nelson J, Stoneking T, Pepin K, Spieth J, Sekhon M, Armstrong J, Becker M, Belter E, Cordum H, Cordes M, Courtney L, Courtney W, Dante M, Du H, Edwards J, Fryman J, Haakensen B, Lamar E, Latreille P, Leonard S, Meyer R, Mulvaney E, Ozersky P, Riley A, Strowmatt C, Wagner-McPherson C, Wollam A, Yoakum M, Bell M, Dedhia N, Parnell L, Shah R, Rodriguez M, See LH, Vil D, Baker J, Kirchoff K, Toth K, King L, Bahret A, Miller B, Marra M, Martienssen R, McCombie WR, Wilson RK, Murphy G, Bancroft I, Volckaert G, Wambutt R, D?sterh?ft A, Stiekema W, Pohl T, Entian KD, Terryn N, Hartley N, Bent E, Johnson S, Langham SA, McCullagh B, Robben J, Grymonprez B, Zimmermann W, Ramsperger U, Wedler H, Balke K, Wedler E, Peters S, van Staveren M, Dirkse W, Mooijman P, Lankhorst RK, Weitzenegger T, Bothe G, Rose M, Hauf J, Berneiser S, Hempel S, Feldpausch M, Lamberth S, Villarroel R, Gielen J, Ardiles W, Bents O, Lemcke K, Kolesov G, Mayer K, Rudd S, Schoof H, Schueller C, Zaccaria P, Mewes HW, Bevan M, Fransz P, , ,
Nature408(6814)823-6(2000 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
NIK1 activation mediates the translocation of RPL10 to the nucleus, where it interacts with LIMYB to fully down-regulate translational machinery genes, resulting in translation inhibition of host and viral mRNAs and enhanced tolerance to begomovirus.
Title: NIK1, a host factor specialized in antiviral defense or a novel general regulator of plant immunity?
the constitutive activation of NIK1, a virulence target of the begomovirus nuclear shuttle protein (NSP), leads to global translation suppression and translocation of the downstream component RPL10 to the nucleus
Title: NIK1-mediated translation suppression functions as a plant antiviral immunity mechanism.
Geminivirus infection directly interferes with NIK1-mediated nuclear relocalization of rpL10A as a counterdefensive measure.
Title: Regulated nuclear trafficking of rpL10A mediated by NIK1 represents a defense strategy of plant cells against virus.
The following NIK1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NIK1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OAb18547 | |
Clone ID Related Accession (Same CDS sequence) | NM_121605.3 | |
Accession Version | NM_121605.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-13 | |
Organism | Arabidopsis thaliana(thale cress) | |
Product | NSP-interacting kinase 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003076). On Sep 12, 2016 this sequence version replaced NM_121605.2. |
1 | ATGGAGAGTA CTATTGTTAT GATGATGATG ATAACAAGAT CTTTCTTTTG CTTCTTGGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_197104.1 |
CDS | 331..2247 |
Translation |
Target ORF information:
Target ORF information:
|
NM_121605.3 |
1 | ATGGAGAGTA CTATTGTTAT GATGATGATG ATAACAAGAT CTTTCTTTTG CTTCTTGGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. |