Gene Symbol | CYP11A1 |
Entrez Gene ID | 338048 |
Full Name | cytochrome P450, family 11, subfamily A, polypeptide 1 |
Synonyms | CYP11A,CYPXIA1,P450(scc) |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » CYP11A1 cDNA ORF clone
Gene Symbol | CYP11A1 |
Entrez Gene ID | 338048 |
Full Name | cytochrome P450, family 11, subfamily A, polypeptide 1 |
Synonyms | CYP11A,CYPXIA1,P450(scc) |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_176644.2 | NP_788817.1 | cholesterol side-chain cleavage enzyme, mitochondrial precursor |
Pan troglodytes (chimpanzee) | CYP11A1 | XP_001164690.3 |
Canis lupus familiaris (dog) | CYP11A1 | XP_535539.2 |
Danio rerio (zebrafish) | cyp11a1 | NP_694485.2 |
Rattus norvegicus (Norway rat) | Cyp11a1 | NP_058982.1 |
Danio rerio (zebrafish) | LOC563363 | XP_691817.1 |
Mus musculus (house mouse) | Cyp11a1 | NP_062753.3 |
Gallus gallus (chicken) | CYP11A1 | NP_001001756.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100495360 | XP_002934608.1 |
Homo sapiens (human) | CYP11A1 | NP_000772.2 |
Bos taurus (cattle) | CYP11A1 | NP_788817.1 |
Expression of Cholesterol Hydroxylase/Lyase System Proteins in Yeast S. cerevisiae Cells as a Self-Processing Polyprotein.
Efimova VS, Isaeva LV, Makeeva DS, Rubtsov MA, Novikova LA
Molecular biotechnology59(9-10)394-406(2017 Oct)
2?- and 16?-hydroxylase activity of CYP11A1 and direct stimulatory effect of estrogens on pregnenolone formation.
Mosa A, Neunzig J, Gerber A, Zapp J, Hannemann F, Pilak P, Bernhardt R
The Journal of steroid biochemistry and molecular biology1501-10(2015 Jun)
Lumisterol is metabolized by CYP11A1: discovery of a new pathway.
Tuckey RC, Slominski AT, Cheng CY, Chen J, Kim TK, Xiao M, Li W
The international journal of biochemistry & cell biology5524-34(2014 Oct)
Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1.
Heo GY, Liao WL, Turko IV, Pikuleva IA
Archives of biochemistry and biophysics518(2)119-26(2012 Feb)
Comparison of cAMP-responsive DNA sequences and their binding proteins associated with expression of the bovine CYP17 and CYP11A and human CYP21B genes.
Waterman MR, Kagawa N, Zanger UM, Momoi K, Lund J, Simpson ER
The Journal of steroid biochemistry and molecular biology43(8)931-5(1992 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Bovine CYP11A1 manifests 2beta- and 16beta-hydroxylase activity.
Title: 2?- and 16?-hydroxylase activity of CYP11A1 and direct stimulatory effect of estrogens on pregnenolone formation.
Data indicate a role of cytochrome P450 11A1 (CYP11A1 in sterol metabolism.
Title: Lumisterol is metabolized by CYP11A1: discovery of a new pathway.
Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1.
Title: Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1.
Kinetic and optical biosensor study of adrenodoxin mutant AdxS112W displaying an enhanced interaction towards the cholesterol side chain cleavage enzyme (CYP11A1).
Title: Kinetic and optical biosensor study of adrenodoxin mutant AdxS112W displaying an enhanced interaction towards the cholesterol side chain cleavage enzyme (CYP11A1).
Data suggest that the upstream region of gene encoding CYP11A contains unique cAMP-responsive sequence and appears to bind unique nuclear proteins or transcription factors in adrenal cortex.
Title: Comparison of cAMP-responsive DNA sequences and their binding proteins associated with expression of the bovine CYP17 and CYP11A and human CYP21B genes.
The following CYP11A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP11A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa43663 | |
Clone ID Related Accession (Same CDS sequence) | NM_176644.2 | |
Accession Version | NM_176644.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-19 | |
Organism | Bos taurus(cattle) | |
Product | cholesterol side-chain cleavage enzyme, mitochondrial precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from K02130.1. On or before Dec 7, 2011 this sequence version replaced XM_003587562.1, NM_176644.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: K02130.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145417 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGCTAGCAA GGGGGCTTCC CCTCCGCTCA GCCCTGGTCA AAGCCTGCCC ACCCATCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_788817.1 |
CDS | 22..1584 |
Translation |
Target ORF information:
Target ORF information:
|
NM_176644.2 |
1 | ATGCTAGCAA GGGGGCTTCC CCTCCGCTCA GCCCTGGTCA AAGCCTGCCC ACCCATCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Expression of Cholesterol Hydroxylase/Lyase System Proteins in Yeast S. cerevisiae Cells as a Self-Processing Polyprotein. |
2?- and 16?-hydroxylase activity of CYP11A1 and direct stimulatory effect of estrogens on pregnenolone formation. |
Lumisterol is metabolized by CYP11A1: discovery of a new pathway. |
Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1. |
Comparison of cAMP-responsive DNA sequences and their binding proteins associated with expression of the bovine CYP17 and CYP11A and human CYP21B genes. |