Gene Symbol | dhc-1 |
Entrez Gene ID | 172041 |
Full Name | Dynein Heavy Chain |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » dhc-1 cDNA ORF clone
Gene Symbol | dhc-1 |
Entrez Gene ID | 172041 |
Full Name | Dynein Heavy Chain |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001330925.1 | NP_001317773.1 | Dynein heavy chain, cytoplasmic |
NM_058962.5 | NP_491363.1 | Dynein heavy chain, cytoplasmic |
NM_001330925.2 | NP_001317773.1 | Dynein heavy chain, cytoplasmic |
NM_058962.4 | NP_491363.1 | Dynein heavy chain, cytoplasmic |
Neurospora crassa | NCU06976 | XP_962616.1 |
Homo sapiens (human) | DYNC1H1 | NP_001367.2 |
Rattus norvegicus (Norway rat) | Dync1h1 | NP_062099.3 |
Danio rerio (zebrafish) | dync1h1 | NP_001036210.1 |
Drosophila melanogaster (fruit fly) | Dhc64C | NP_523929.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002015 | XP_003436004.1 |
Mus musculus (house mouse) | Dync1h1 | NP_084514.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_11205 | XP_003714413.1 |
Pan troglodytes (chimpanzee) | DYNC1H1 | XP_003314564.1 |
Gallus gallus (chicken) | DYNC1H1 | XP_421371.3 |
LOC718989 | XP_001112455.2 | |
Canis lupus familiaris (dog) | DYNC1H1 | XP_537556.2 |
Bos taurus (cattle) | DYNC1H1 | NP_001193067.1 |
Caenorhabditis elegans (roundworm) | dhc-1 | NP_491363.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Dynein tethered to the cell cortex generates pulling forces that position the mitotic spindle. Two distinct cortical dynein populations together create a robust force-generating system in the polarized one-cell Caenorhabditis elegans embryo.
Title: Two populations of cytoplasmic dynein contribute to spindle positioning in
we dissect the role of dynactin's microtubule binding activity, located in the p150 CAP-Gly domain and an adjacent basic patch, in the C. elegans zygote. Our results suggest that p150 GAP-Gly domain binding to microtubules promotes initiation of dynein-mediated organelle transport in the dividing one-cell embryo, and that this function of p150 is critical for generating cytoplasmic pulling forces for centrosome
Title: Dynactin binding to tyrosinated microtubules promotes centrosome centration in C. elegans by enhancing dynein-mediated organelle transport.
Mutations affecting dhc-1 and cyb-3 cooperate to increase fitness in the absence of MDF-1.
Title: Cyclin B3 and dynein heavy chain cooperate to increase fitness in the absence of mdf-1/MAD1 in Caenorhabditis elegans.
Data present evidence that bicd-1 operates in a conserved pathway with dhc-1 and unc-116.
Title: C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites.
Data show that accumulation of dynein at poles was kinesin-1 independent and APC dependent, just like dynein driven spindle movements.
Title: Kinesin-1 and cytoplasmic dynein act sequentially to move the meiotic spindle to the oocyte cortex in Caenorhabditis elegans.
The following dhc-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dhc-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa336154 | |
Clone ID Related Accession (Same CDS sequence) | NM_001330925.1 , NM_001330925.2 | |
Accession Version | NM_001330925.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 10911bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Dynein heavy chain, cytoplasmic | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGACTGCAC AAACCTTGTA CATTAGTCCA AGCACTCGTG AAACTCGTGA GAAGATTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001317773.1 |
CDS | 1..10911 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001330925.1 |
1 | ATGACTGCAC AAACCTTGTA CATTAGTCCA AGCACTCGTG AAACTCGTGA GAAGATTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336154 | |
Clone ID Related Accession (Same CDS sequence) | NM_001330925.1 , NM_001330925.2 | |
Accession Version | NM_001330925.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 10911bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Dynein heavy chain, cytoplasmic | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001330925.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGACTGCAC AAACCTTGTA CATTAGTCCA AGCACTCGTG AAACTCGTGA GAAGATTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001317773.1 |
CDS | 1..10911 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001330925.2 |
1 | ATGACTGCAC AAACCTTGTA CATTAGTCCA AGCACTCGTG AAACTCGTGA GAAGATTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336522 | |
Clone ID Related Accession (Same CDS sequence) | NM_058962.5 , NM_058962.4 | |
Accession Version | NM_058962.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 13707bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Dynein heavy chain, cytoplasmic | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_058962.4. |
1 | ATGGATAGTG GGAATGAAAG TAGCATTATC CAACCGCCAA ACTTAAAAAC CGCAGCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491363.1 |
CDS | 8..13714 |
Translation |
Target ORF information:
Target ORF information:
|
NM_058962.5 |
1 | ATGGATAGTG GGAATGAAAG TAGCATTATC CAACCGCCAA ACTTAAAAAC CGCAGCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336522 | |
Clone ID Related Accession (Same CDS sequence) | NM_058962.5 , NM_058962.4 | |
Accession Version | NM_058962.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 13707bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Dynein heavy chain, cytoplasmic | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_058962.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGATAGTG GGAATGAAAG TAGCATTATC CAACCGCCAA ACTTAAAAAC CGCAGCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491363.1 |
CDS | 1..13707 |
Translation |
Target ORF information:
Target ORF information:
|
NM_058962.4 |
1 | ATGGATAGTG GGAATGAAAG TAGCATTATC CAACCGCCAA ACTTAAAAAC CGCAGCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |