DYNC1H1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DYNC1H1
Entrez Gene ID	1778
Full Name	dynein cytoplasmic 1 heavy chain 1
Synonyms	CMT2O,DHC1,DHC1a,DNCH1,DNCL,DNECL,DYHC,Dnchc1,HL-3,SMALED1,p22
General protein information	Preferred Names dynein cytoplasmic 1 heavy chain 1 Names cytoplasmic dynein 1 heavy chain 1 dynein heavy chain, cytosolic dynein, cytoplasmic, heavy polypeptide 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q32.31
Summary	Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008].
Disorder MIM:	600112
Disorder Html:	Charcot-Marie-Tooth disease, axonal, type 20, 614228 (3); Mental retardation, autosomal dominant 13, 614563 (3); Spinal muscular atrophy, lower extremity-predominant 1, AD, 158600 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001376.5	NP_001367.2	cytoplasmic dynein 1 heavy chain 1
NM_001376.4	NP_001367.2	cytoplasmic dynein 1 heavy chain 1

Pathways from BioSystems

Homologies

Neurospora crassa	NCU06976	XP_962616.1
Homo sapiens (human)	DYNC1H1	NP_001367.2
Rattus norvegicus (Norway rat)	Dync1h1	NP_062099.3
Danio rerio (zebrafish)	dync1h1	NP_001036210.1
Drosophila melanogaster (fruit fly)	Dhc64C	NP_523929.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002015	XP_003436004.1
Mus musculus (house mouse)	Dync1h1	NP_084514.2
Magnaporthe oryzae (rice blast fungus)	MGG_11205	XP_003714413.1
Pan troglodytes (chimpanzee)	DYNC1H1	XP_003314564.1
Gallus gallus (chicken)	DYNC1H1	XP_421371.3
	LOC718989	XP_001112455.2
Canis lupus familiaris (dog)	DYNC1H1	XP_537556.2
Bos taurus (cattle)	DYNC1H1	NP_001193067.1
Caenorhabditis elegans (roundworm)	dhc-1	NP_491363.1

Gene Ontology
Bibliography

Related articles in PubMed

A missense mutation in DYNC1H1 gene causing spinal muscular atrophy - Lower extremity, dominant.
Das J, Lilleker JB, Jabbal K, Ealing J
Neurologia i neurochirurgia polska(2017 Dec)

NuMA recruits dynein activity to microtubule minus-ends at mitosis.
Hueschen CL, Kenny SJ, Xu K, Dumont S
eLife6(2017 Nov)

Expanding the phenotypic spectrum associated with mutations of DYNC1H1.
Beecroft SJ, McLean CA, Delatycki MB, Koshy K, Yiu E, Haliloglu G, Orhan D, Lamont PJ, Davis MR, Laing NG, Ravenscroft G
Neuromuscular disorders : NMD27(7)607-615(2017 Jul)

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle.
Chu X, Chen X, Wan Q, Zheng Z, Du Q
The Journal of biological chemistry291(38)20055-67(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that cytoplasmic dynein 1 binds to BRCA2 through the latter's centrosomal localization signal and BRCA2 mediates the cohesion between centrosomes during the S phase, potentially serving as a cell-cycle checkpoint.
Title: BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.

A novel de novo mutation (c.2327C > T, p.P776L) in the DYNC1H1 gene identified and confirmed it as the causal variant of Spinal muscular atrophy with lower extremity predominance.
Title: Identification of a de novo DYNC1H1 mutation via WES according to published guidelines.

Our findings suggest that DYNC1H1 variants can cause not only lower, but also upper motor neuron disease.
Title: Mutation screen reveals novel variants and expands the phenotypes associated with DYNC1H1.

The mutations in DYNC1H1 increase the interaction with its adaptor BICD2.
Title: Novel mutations in the DYNC1H1 tail domain refine the genetic and clinical spectrum of dyneinopathies.

Report expands the clinical spectrum of DYNC1H1-related spinal muscular atrophy to include generalized arthrogryposis
Title: Novel mutations expand the clinical spectrum of DYNC1H1-associated spinal muscular atrophy.

The following DYNC1H1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DYNC1H1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26236	NM_001376.5 Latest version!	Homo sapiens dynein cytoplasmic 1 heavy chain 1 (DYNC1H1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price
View Old Accession Versions >>
OHu26236	NM_001376.4	Homo sapiens dynein cytoplasmic 1 heavy chain 1 (DYNC1H1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DYNC1H1 ( NM_001376.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001367.2 Homo sapiens dynein cytoplasmic 1 heavy chain 1 (DYNC1H1), mRNA.

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CloneID	OHu26236
Clone ID Related Accession (Same CDS sequence)	NM_001376.5 , NM_001376.4
Accession Version	NM_001376.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 13941bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	cytoplasmic dynein 1 heavy chain 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB290157.1, AB002323.3, DB508175.2 and AL118558.6. On Nov 23, 2018 this sequence version replaced NM_001376.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB290157.1, AB002323.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000360184.10/ ENSP00000348965.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGGAGC CCGGGGGCGG CGGCGGCGAG GACGGCTCGG CCGGATTGGA AGTGTCGGCC 
GTGCAGAATG TGGCGGACGT GTCGGTGCTG CAGAAGCACC TGCGCAAGCT GGTGCCGCTG 
CTGCTGGAGG ACGGCGGCGA GGCGCCGGCC GCGCTGGAGG CGGCGCTGGA GGAGAAGAGC 
GCCCTGGAGC AGATGCGCAA GTTCCTTTCG GACCCGCAGG TCCACACGGT GCTGGTGGAG 
CGCTCCACGC TCAAAGAGGA CGTCGGTGAT GAAGGAGAAG AAGAAAAAGA ATTCATTTCC 
TATAACATCA ACATAGACAT TCATTATGGG GTTAAATCCA ATAGCTTGGC ATTCATTAAA 
CGTACTCCCG TGATTGATGC AGATAAACCC GTGTCTTCTC AGCTCCGGGT CCTTACACTC 
AGTGAAGACT CGCCCTACGA AACTTTGCAT TCTTTCATTA GCAATGCAGT GGCTCCTTTT 
TTTAAGTCCT ACATTAGAGA GTCTGGCAAG GCAGACAGGG ATGGTGATAA AATGGCTCCT 
TCAGTTGAAA AGAAGATTGC AGAACTCGAA ATGGGACTCC TTCACTTGCA GCAAAATATT 
GAAATTCCGG AGATCAGCCT GCCGATTCAT CCAATGATCA CAAATGTTGC AAAACAGTGT 
TATGAGCGTG GAGAAAAGCC AAAAGTTACA GACTTTGGTG ATAAGGTTGA AGACCCAACA 
TTTCTTAATC AGTTACAATC TGGAGTTAAC CGCTGGATCC GAGAAATTCA AAAAGTGACC 
AAACTGGATC GAGATCCTGC ATCAGGAACT GCCTTACAGG AAATTAGTTT TTGGCTAAAC 
TTGGAACGTG CGTTATACCG CATCCAGGAG AAACGGGAGA GCCCGGAAGT TCTCCTGACT 
CTGGATATCT TGAAACATGG CAAGCGCTTC CATGCCACCG TCAGTTTTGA CACTGACACA 
GGTCTAAAAC AGGCTTTGGA AACTGTGAAT GACTACAATC CTCTGATGAA AGATTTCCCT 
CTGAATGATT TGCTGTCTGC CACGGAGCTG GACAAAATAA GACAGGCGCT TGTTGCCATT 
TTCACACATT TGAGAAAGAT CCGAAACACA AAATATCCTA TTCAGAGGGC ACTGCGTTTG 
GTGGAGGCAA TTTCAAGAGA CTTGAGTTCT CAATTACTCA AAGTATTGGG CACTAGGAAA 
TTGATGCATG TTGCTTATGA AGAATTTGAA AAAGTTATGG TAGCATGCTT TGAAGTTTTT 
CAGACTTGGG ATGATGAGTA TGAGAAACTT CAGGTATTGT TGAGAGACAT CGTCAAAAGA 
AAAAGGGAAG AAAATCTGAA GATGGTGTGG CGTATCAACC CTGCCCACAG GAAGCTGCAG 
GCCCGCCTTG ACCAGATGAG AAAATTTAGA CGCCAGCATG AACAGCTAAG AGCTGTTATC 
GTCAGGGTCC TGAGGCCACA GGTCACGGCA GTTGCACAAC AGAATCAAGG AGAGGTCCCT 
GAACCCCAAG ATATGAAAGT GGCTGAGGTT CTCTTTGATG CTGCAGATGC AAATGCCATT 
GAGGAAGTAA ACCTTGCTTA TGAGAACGTC AAGGAAGTGG ATGGACTGGA TGTTTCCAAA 
GAGGGCACGG AAGCCTGGGA GGCTGCTATG AAGAGGTACG ATGAGAGGAT CGACAGAGTG 
GAGACCCGGA TCACCGCTCG CCTTCGGGAT CAGCTTGGCA CAGCCAAGAA TGCCAACGAG 
ATGTTTAGGA TTTTCTCCAG GTTTAATGCA CTGTTTGTCA GGCCTCACAT CCGTGGGGCC 
ATTCGCGAAT ACCAGACCCA GCTGATCCAG CGCGTGAAAG ATGACATTGA GTCTCTTCAC 
GACAAGTTCA AGGTCCAGTA CCCACAGAGT CAGGCTTGTA AGATGAGTCA CGTTCGTGAC 
TTGCCCCCTG TGTCAGGGTC TATCATCTGG GCTAAACAGA TCGACAGGCA GCTGACGGCC 
TACATGAAGC GGGTGGAAGA TGTCCTTGGC AAGGGCTGGG AGAATCACGT GGAGGGGCAG 
AAGCTGAAGC AGGATGGAGA CAGCTTCCGC ATGAAGCTCA ACACGCAGGA GATCTTTGAT 
GACTGGGCAA GGAAGGTGCA GCAGCGCAAC CTCGGTGTCT CGGGGCGCAT TTTCACCATC 
GAAAGTACTC GGGTTCGGGG CCGAACTGGA AATGTGCTTA AGCTGAAAGT TAACTTTCTT 
CCTGAGATTA TCACACTATC CAAAGAAGTC CGGAACCTCA AATGGCTTGG TTTCCGCGTC 
CCACTGGCGA TTGTGAACAA AGCCCATCAA GCAAACCAGC TTTACCCGTT TGCCATCTCA 
CTGATCGAGA GCGTTCGTAC CTATGAACGG ACCTGCGAGA AGGTGGAGGA GCGGAACACC 
ATTTCCCTTT TGGTGGCTGG CTTGAAAAAG GAAGTGCAGG CCCTGATCGC AGAAGGCATT 
GCGTTGGTGT GGGAGTCCTA CAAACTTGAC CCATATGTAC AGCGCTTAGC AGAGACTGTC 
TTCAACTTCC AAGAAAAGGT GGATGATCTG CTGATCATTG AAGAAAAAAT AGACCTAGAA 
GTCCGTTCCT TGGAAACTTG TATGTATGAC CATAAGACAT TCTCGGAAAT CTTGAACAGA 
GTCCAGAAAG CAGTGGATGA CTTAAATCTG CACTCCTATT CCAATTTGCC CATCTGGGTC 
AACAAGCTTG ACATGGAGAT TGAAAGAATA TTGGGCGTCC GTCTGCAAGC TGGCCTGAGA 
GCTTGGACGC AGGTTCTTCT TGGACAAGCT GAAGATAAAG CAGAAGTTGA CATGGACACA 
GATGCTCCAC AAGTTAGTCA CAAGCCTGGT GGAGAGCCAA AGATCAAAAA TGTCGTTCAT 
GAGCTAAGAA TAACCAATCA GGTAATCTAC TTGAATCCAC CAATTGAAGA GTGCAGATAC 
AAGCTGTATC AGGAAATGTT TGCCTGGAAG ATGGTTGTAC TGTCTCTCCC CAGGATCCAG 
AGTCAGAGGT ACCAGGTGGG TGTACATTAC GAATTGACTG AGGAAGAGAA ATTCTATCGG 
AATGCTTTAA CACGGATGCC TGATGGCCCT GTTGCCCTGG AAGAGTCGTA TTCTGCTGTC 
ATGGGCATTG TATCTGAAGT TGAACAGTAT GTCAAGGTTT GGCTTCAGTA TCAGTGTTTA 
TGGGATATGC AAGCTGAAAA CATCTATAAC AGACTTGGAG AAGATCTCAA CAAATGGCAG 
GCTCTCCTGG TCCAAATAAG GAAGGCCAGA GGAACCTTTG ACAATGCAGA AACCAAGAAA 
GAGTTTGGAC CAGTAGTTAT AGATTATGGC AAGGTACAAT CTAAGGTGAA CTTGAAATAT 
GACTCTTGGC ATAAGGAGGT TCTTAGCAAA TTTGGGCAGA TGCTAGGATC AAACATGACG 
GAATTCCATT CCCAGATCTC AAAGTCCCGC CAAGAGTTGG AGCAGCACTC AGTAGACACG 
GCCAGCACCT CCGATGCAGT GACCTTCATC ACCTATGTGC AGTCTTTGAA ACGGAAGATC 
AAGCAGTTTG AGAAGCAAGT TGAGCTCTAC CGCAATGGCC AGCGCTTACT GGAAAAGCAA 
AGGTTCCAGT TCCCACCTTC CTGGCTTTAT ATTGACAACA TCGAGGGAGA GTGGGGAGCC 
TTCAATGACA TCATGCGGCG AAAGGACTCT GCCATTCAGC AGCAGGTGGC AAACCTGCAA 
ATGAAGATTG TCCAGGAGGA TCGGGCCGTG GAAAGCCGCA CCACCGACCT GCTGACTGAC 
TGGGAGAAGA CCAAGCCTGT CACGGGCAAC CTTCGCCCAG AAGAGGCACT TCAGGCTCTC 
ACCATATATG AGGGGAAGTT TGGTAGGCTG AAGGACGACA GAGAGAAGTG TGCAAAGGCC 
AAGGAGGCGC TGGAATTGAC AGATACTGGG CTTCTCAGTG GCAGTGAAGA GCGCGTGCAG 
GTGGCCTTAG AAGAATTACA GGACCTCAAA GGCGTTTGGT CAGAACTTTC TAAGGTTTGG 
GAGCAAATCG ATCAGATGAA GGAGCAACCC TGGGTTTCAG TACAGCCTCG AAAGCTTCGA 
CAAAATTTGG ATGCCCTCCT GAACCAGCTG AAAAGCTTCC CTGCCCGGTT GCGACAGTAT 
GCGTCCTATG AGTTTGTTCA GAGGCTTCTG AAAGGTTACA TGAAGATAAA TATGCTGGTG 
ATTGAACTGA AATCCGAAGC ACTTAAAGAC CGCCATTGGA AACAGCTCAT GAAAAGGCTT 
CACGTTAATT GGGTTGTTTC TGAGCTAACC CTTGGCCAAA TCTGGGATGT TGACTTGCAG 
AAAAATGAAG CGATTGTCAA GGATGTACTG CTTGTGGCAC AAGGGGAGAT GGCTTTGGAA 
GAATTTTTGA AGCAGATAAG AGAAGTGTGG AATACTTATG AACTAGACTT GGTTAATTAT 
CAGAACAAGT GCCGCTTGAT CCGTGGCTGG GATGACCTCT TCAACAAGGT CAAAGAACAC 
ATCAACAGCG TCTCGGCCAT GAAGCTCTCT CCGTATTACA AGGTTTTTGA AGAGGATGCT 
CTCAGCTGGG AAGATAAGCT GAACAGGATC ATGGCTCTCT TTGATGTGTG GATTGATGTG 
CAGAGGCGGT GGGTCTACCT GGAAGGTATC TTCACAGGCA GTGCAGATAT CAAGCACCTG 
CTGCCAGTGG AAACCCAGCG GTTTCAGAGC ATCAGCACTG AGTTTTTGGC TCTAATGAAA 
AAAGTGTCCA AGTCTCCCCT TGTTATGGAT GTTCTGAACA TCCAGGGAGT ACAGAGGTCT 
CTGGAAAGAT TGGCAGACCT GCTAGGAAAG ATCCAGAAAG CATTGGGAGA ATATCTGGAA 
AGAGAGCGGT CATCTTTCCC CAGGTTCTAT TTTGTGGGTG ATGAAGATTT GCTTGAAATC 
ATTGGAAACA GCAAGAATGT CGCTAAATTA CAGAAACACT TCAAGAAGAT GTTTGCTGGA 
GTTTCGAGCA TCATCCTGAA CGAGGATAAC TCTGTTGTTT TGGGTATTTC ATCTCGGGAA 
GGAGAGGAGG TTATGTTTAA AACTCCTGTG TCAATTACTG AACATCCCAA AATCAATGAG 
TGGCTCACAT TGGTAGAAAA GGAGATGAGA GTCACCCTGG CCAAACTGCT TGCTGAGTCT 
GTTACGGAAG TTGAGATTTT TGGTAAAGCA ACTTCAATTG ACCCAAATAC CTACATCACT 
TGGATTGATA AATACCAGGC CCAGCTTGTG GTTTTGTCAG CCCAGATAGC CTGGTCTGAG 
AACGTGGAGA CCGCACTGAG CAGCATGGGC GGAGGTGGAG ATGCCGCGCC CTTGCACTCT 
GTGCTGAGCA ATGTGGAGGT CACCCTCAAT GTGTTAGCAG ACTCTGTCCT CATGGAGCAG 
CCCCCACTCC GAAGGCGGAA GCTAGAACAC TTGATTACAG AGTTGGTTCA CCAGAGAGAT 
GTTACAAGGT CCTTGATCAA AAGCAAGATT GACAACGCCA AATCTTTTGA ATGGCTCAGC 
CAGATGCGAT TTTACTTTGA CCCTAAGCAA ACTGATGTGT TACAGCAGTT GTCAATTCAA 
ATGGCAAATG CCAAATTTAA CTATGGCTTT GAGTACCTGG GTGTTCAGGA CAAACTGGTC 
CAGACCCCCC TCACTGACCG CTGCTATTTG ACAATGACAC AAGCCTTGGA GGCCAGGCTG 
GGGGGTTCCC CATTTGGACC TGCTGGAACT GGGAAAACAG AGTCTGTCAA AGCTCTTGGC 
CATCAGCTTG GACGGTTTGT TTTAGTTTTC AACTGTGATG AAACCTTTGA TTTCCAGGCA 
ATGGGCCGGA TCTTTGTGGG CCTTTGCCAG GTGGGTGCCT GGGGCTGCTT TGACGAGTTC 
AACCGCCTGG AGGAGCGGAT GCTCTCGGCT GTGTCCCAGC AGGTGCAGTG CATACAGGAA 
GCACTGCGTG AACATTCCAA CCCCAACTAC GACAAGACCT CTGCCCCCAT TACTTGTGAG 
CTGCTGAACA AACAAGTCAA GGTGAGCCCG GACATGGCCA TCTTCATCAC CATGAACCCT 
GGCTACGCGG GCCGGTCTAA CCTTCCTGAC AACTTGAAGA AGCTGTTCCG GAGCTTGGCC 
ATGACCAAGC CCGACCGGCA GTTAATCGCC CAGGTCATGC TGTACTCACA GGGTTTCCGC 
ACTGCTGAAG TGCTTGCCAA CAAAATCGTC CCGTTTTTTA AACTATGCGA TGAGCAGCTC 
TCTTCCCAAA GCCATTATGA CTTCGGTCTT CGGGCTTTGA AGAGTGTGCT GGTGAGTGCA 
GGCAATGTGA AGAGAGAGAG AATCCAGAAG ATAAAGAGGG AGAAAGAGGA ACGAGGGGAA 
GCAGTTGATG AAGGAGAAAT TGCTGAAAAT CTCCCTGAAC AAGAGATTCT GATACAGAGC 
GTCTGTGAGA CGATGGTGCC AAAGCTGGTG GCAGAGGACA TCCCGCTGCT CTTCAGCCTC 
CTGTCGGACG TGTTCCCTGG AGTCCAGTAT CACAGGGGTG AGATGACTGC CCTTCGAGAG 
GAGCTGAAGA AAGTGTGTCA GGAGATGTAT TTGACATATG GAGATGGAGA AGAAGTTGGT 
GGAATGTGGG TTGAAAAGGT TCTCCAGCTC TATCAGATCA CCCAGATCAA TCATGGCCTG 
ATGATGGTGG GGCCCTCGGG AAGTGGGAAG AGCATGGCCT GGCGTGTCCT GCTGAAGGCA 
TTGGAGAGAC TCGAGGGTGT GGAAGGTGTG GCCCATATCA TCGACCCCAA GGCCATCAGC 
AAAGACCACC TCTACGGAAC CCTGGACCCC AACACCAGGG AATGGACAGA TGGGCTCTTC 
ACACACGTGC TGAGAAAGAT CATCGACAGC GTGAGAGGCG AGCTGCAGAA GCGCCAGTGG 
ATCGTCTTCG ATGGCGATGT GGATCCAGAG TGGGTTGAGA ACTTGAACTC AGTGCTGGAT 
GACAATAAGC TCCTAACTTT GCCCAATGGA GAGCGCCTCA GTCTTCCACC CAATGTGAGA 
ATAATGTTTG AGGTACAGGA CTTGAAATAC GCGACCTTGG CCACAGTGTC GCGCTGCGGC 
ATGGTCTGGT TCAGTGAGGA TGTGCTGAGC ACCGACATGA TCTTCAACAA CTTCCTGGCC 
AGGCTGCGCA GCATCCCGCT GGATGAAGGG GAGGATGAGG CACAGCGGCG GCGTAAGGGC 
AAAGAGGATG AGGGGGAGGA GGCCGCTTCC CCCATGCTGC AGATCCAAAG AGATGCAGCT 
ACGATCATGC AACCGTACTT CACGTCCAAC GGCCTGGTCA CCAAGGCGCT AGAGCACGCC 
TTCCAGCTGG AGCACATCAT GGACCTAACA CGCCTGCGCT GCCTGGGCTC GCTCTTCTCC 
ATGCTGCACC AGGCCTGCCG CAACGTGGCG CAGTATAACG CCAACCATCC CGACTTCCCC 
ATGCAGATCG AGCAGCTGGA GCGCTACATT CAGCGATATC TGGTTTATGC CATACTCTGG 
TCCCTGTCTG GAGACAGCCG GCTAAAAATG AGAGCAGAGC TGGGTGAATA CATCAGAAGA 
ATCACGACCG TGCCTCTGCC CACTGCGCCC AACATACCCA TTATCGATTA TGAGGTGTCC 
ATCAGCGGAG AATGGTCTCC GTGGCAGGCC AAGGTGCCTC AGATTGAAGT GGAGACGCAC 
AAGGTGGCAG CCCCTGATGT CGTCGTGCCA ACGCTGGACA CAGTCCGCCA CGAAGCCCTC 
TTGTACACTT GGCTGGCCGA ACACAAGCCC CTGGTCTTGT GTGGCCCTCC TGGGTCTGGC 
AAGACCATGA CACTCTTCAG CGCCCTCCGG GCCTTGCCTG ACATGGAGGT GGTGGGTCTC 
AACTTCTCCA GTGCTACTAC TCCAGAGCTG CTTCTGAAGA CTTTTGATCA CTACTGCGAG 
TACAGGCGCA CACCTAATGG GGTGGTTTTG GCTCCTGTTC AACTTGGAAA GTGGCTGGTG 
TTGTTCTGTG ATGAAATCAA CTTGCCAGAT ATGGATAAAT ATGGGACCCA GAGGGTCATA 
TCCTTCATCA GACAGATGGT GGAGCACGGA GGCTTTTACC GTACCTCAGA TCAAACATGG 
GTGAAGCTGG AGAGAATCCA GTTTGTTGGG GCTTGTAATC CCCCCACAGA CCCTGGAAGA 
AAGCCCCTCT CACACAGGTT CCTGCGCCAC GTGCCTGTCG TGTATGTGGA TTACCCGGGC 
CCCGCCTCCC TCACACAGAT CTACGGCACC TTCAACCGCG CCATGCTGAG GCTCATTCCA 
TCCCTGCGGA CGTATGCAGA GCCGCTCACT GCTGCCATGG TGGAGTTCTA CACCATGTCT 
CAGGAGAGAT TCACCCAGGA TACACAACCT CACTATATCT ATTCACCCCG TGAAATGACT 
AGGTGGGTGA GAGGCATCTT TGAAGCGCTG AGACCTCTGG AGACCCTGCC TGTTGAAGGC 
CTCATTCGGA TTTGGGCACA TGAAGCTCTG CGTCTCTTCC AAGATAGACT CGTAGAGGAT 
GAGGAGAGGC GTTGGACTGA TGAGAACATC GACACGGTTG CTCTGAAGCA CTTCCCTAAC 
ATCGACAGAG AGAAGGCAAT GAGCCGACCC ATCTTGTACA GCAACTGGCT GTCAAAGGAT 
TACATCCCAG TAGACCAAGA AGAGTTAAGA GATTATGTCA AAGCTAGGCT GAAGGTCTTT 
TATGAAGAAG AACTTGATGT TCCGCTGGTG CTGTTTAATG AAGTCCTAGA CCACGTGCTG 
AGGATTGACA GAATATTCCG TCAACCTCAA GGCCACTTGC TTCTGATTGG TGTTAGTGGA 
GCAGGAAAAA CTACCCTGTC TCGTTTCGTC GCCTGGATGA ACGGTTTGAG TGTGTACCAG 
ATTAAGGTCC ATAGGAAGTA CACAGGGGAA GACTTTGATG AAGATCTACG GACAGTGTTG 
AGACGTTCTG GCTGTAAAAA TGAAAAGATA GCATTTATAA TGGATGAATC TAATGTGTTA 
GATTCTGGAT TCCTGGAGCG AATGAATACC CTTCTGGCCA ATGGAGAGGT GCCTGGTCTC 
TTTGAAGGAG ACGAGTATGC CACCTTGATG ACGCAGTGCA AAGAGGGGGC ACAGAAGGAA 
GGCCTGATGC TGGACTCGCA CGAGGAGCTC TACAAGTGGT TCACTAGCCA GGTTATCCGC 
AACCTCCACG TCGTGTTCAC CATGAACCCG TCCTCGGAGG GACTCAAGGA CCGGGCAGCT 
ACATCACCAG CACTTTTCAA CAGGTGTGTG TTGAATTGGT TTGGAGACTG GTCCACCGAA 
GCACTGTATC AGGTTGGCAA AGAATTCACA AGTAAGATGG ATCTGGAGAA GCCAAATTAC 
ATCGTGCCTG ATTACATGCC AGTTGTGTAT GATAAGCTGC CGCAGCCACC ATCCCATCGG 
GAAGCCATTG TGAACAGCTG TGTGTTTGTT CATCAGACTC TTCACCAGGC GAATGCTCGG 
CTAGCAAAGC GAGGCGGCAG AACGATGGCC ATCACCCCTC GCCACTACCT GGACTTCATC 
AATCACTATG CCAACCTGTT CCACGAGAAG CGGAGCGAGC TGGAGGAGCA GCAGATGCAC 
TTGAACGTGG GGCTCAGGAA GATCAAAGAG ACAGTCGACC AGGTAGAAGA ACTGCGTCGT 
GACTTGAGGA TAAAGAGCCA AGAGCTGGAG GTGAAGAATG CAGCAGCCAA TGACAAGCTG 
AAAAAGATGG TGAAAGACCA GCAGGAGGCT GAAAAGAAGA AGGTTATGAG CCAAGAAATC 
CAGGAACAGC TGCATAAGCA GCAGGAGGTA ATTGCAGACA AACAGATGAG TGTCAAAGAA 
GATCTTGATA AGGTGGAACC TGCCGTCATT GAGGCCCAGA ATGCTGTGAA GTCGATCAAG 
AAGCAGCACC TGGTGGAGGT GAGGTCCATG GCCAACCCTC CTGCTGCTGT GAAGCTGGCG 
CTGGAGTCCA TCTGCCTGCT GCTGGGGGAA AGCACCACAG ACTGGAAGCA GATCCGCTCC 
ATCATCATGC GGGAGAACTT CATCCCCACC ATCGTCAACT TCTCTGCAGA GGAGATCAGT 
GACGCCATAA GGGAGAAGAT GAAGAAAAAT TACATGTCCA ATCCAAGTTA CAATTATGAA 
ATTGTGAATC GGGCTTCCCT GGCTTGCGGC CCTATGGTGA AATGGGCAAT TGCACAGCTT 
AACTATGCAG ACATGTTAAA GAGAGTGGAG CCCCTACGCA ATGAGCTGCA GAAGCTGGAA 
GATGACGCCA AGGACAACCA GCAGAAGGCC AACGAGGTGG AGCAGATGAT CCGAGACCTG 
GAAGCCAGCA TCGCCCGCTA CAAGGAGGAA TACGCCGTCC TGATCTCAGA GGCCCAGGCC 
ATCAAGGCAG ACCTGGCAGC TGTCGAGGCA AAAGTAAACC GGAGCACTGC TCTTCTGAAG 
AGCTTGTCTG CTGAACGTGA ACGATGGGAA AAAACAAGTG AAACTTTCAA AAACCAGATG 
TCCACCATTG CTGGGGACTG TCTCTTGTCA GCTGCGTTCA TTGCCTACGC GGGTTACTTT 
GACCAGCAGA TGCGTCAGAA CTTGTTCACT ACCTGGTCCC ATCACCTACA GCAAGCCAAC 
ATCCAGTTCC GTACAGATAT TGCCAGGACG GAATACCTTT CCAATGCTGA TGAGCGTCTT 
CGCTGGCAGG CCAGCTCCTT GCCTGCTGAT GACCTTTGCA CAGAAAATGC CATCATGCTG 
AAACGATTCA ATAGGTATCC GCTGATCATT GACCCCTCTG GACAGGCCAC AGAATTCATT 
ATGAATGAAT ATAAGGATCG TAAGATCACA CGGACCAGCT TCCTGGATGA CGCCTTCAGA 
AAGAACTTAG AGAGTGCACT GAGATTCGGT AACCCCCTTC TGGTCCAGGA TGTGGAAAGC 
TACGATCCAG TTTTGAACCC GGTGCTGAAC CGTGAAGTGC GGCGAACAGG GGGGAGAGTG 
CTGATCACTC TCGGGGACCA GGACATAGAC CTGTCGCCAT CGTTTGTCAT CTTCCTGTCC 
ACCCGGGATC CAACTGTCGA GTTCCCACCA GATCTCTGTT CCCGGGTTAC TTTTGTAAAC 
TTCACAGTTA CCCGTAGCAG TTTACAAAGC CAGTGTCTAA ATGAAGTACT TAAAGCAGAA 
AGACCTGATG TGGACGAGAA ACGATCTGAT CTTCTTAAAC TTCAAGGGGA ATTTCAGCTC 
CGTTTGCGTC AGCTGGAAAA ATCTCTACTA CAAGCTCTGA ACGAGGTGAA AGGGCGCATT 
TTGGATGACG ACACGATCAT AACCACTCTG GAGAACCTGA AGAGAGAGGC TGCAGAGGTC 
ACCAGGAAAG TTGAGGAGAC GGACATTGTC ATGCAGGAGG TGGAGACCGT GTCCCAGCAG 
TACCTCCCGC TCTCCACCGC CTGCAGCAGC ATCTACTTCA CCATGGAGTC CCTCAAGCAG 
ATACACTTCT TGTACCAGTA CTCCCTCCAG TTTTTCCTGG ACATTTATCA CAACGTCCTA 
TACGAGAACC CGAACCTGAA GGGTGTCACC GACCACACAC AGCGCCTGTC CATTATAACA 
AAGGACCTCT TCCAGGTGGC GTTTAACCGA GTGGCTCGAG GCATGCTGCA TCAGGACCAC 
ATTACCTTTG CCATGCTGCT GGCAAGAATC AAACTGAAGG GCACCGTGGG GGAGCCCACC 
TACGATGCAG AATTCCAGCA CTTCTTGAGA GGAAATGAGA TTGTCCTGAG TGCTGGCTCC 
ACCCCCAGGA TCCAGGGCCT GACTGTGGAG CAGGCGGAGG CGGTGGTGAG GCTGAGCTGC 
CTTCCCGCGT TTAAGGACTT GATTGCAAAG GTTCAGGCAG ACGAGCAATT TGGCATCTGG 
CTGGACAGCA GCTCCCCGGA GCAGACTGTG CCCTACCTCT GGAGTGAAGA AACACCTGCA 
ACACCCATTG GCCAGGCCAT CCACCGCCTG CTCCTGATCC AGGCTTTCCG GCCCGATCGC 
CTGTTGGCCA TGGCCCACAT GTTTGTTTCA ACAAACCTTG GGGAGTCTTT CATGTCCATC 
ATGGAGCAGC CGCTCGACCT GACCCACATT GTGGGCACAG AGGTGAAGCC CAACACTCCT 
GTCTTAATGT GCTCTGTGCC TGGTTATGAT GCCAGTGGAC ATGTCGAGGA CCTTGCAGCC 
GAGCAGAACA CGCAGATCAC TTCAATTGCA ATCGGCTCTG CAGAAGGCTT TAACCAAGCA 
GATAAGGCAA TAAACACCGC TGTAAAGTCG GGCAGGTGGG TGATGCTGAA GAATGTGCAT 
CTGGCCCCAG GGTGGCTGAT GCAGCTGGAG AAGAAGTTGC ATTCCCTGCA GCCGCATGCC 
TGCTTCCGAC TCTTCCTCAC CATGGAGATC AACCCCAAGG TGCCTGTGAA TCTGCTCCGT 
GCGGGCCGCA TCTTTGTGTT CGAGCCACCG CCAGGGGTGA AGGCCAACAT GCTGAGGACG 
TTCAGCAGCA TTCCCGTCTC ACGGATATGC AAGTCTCCCA ACGAGCGTGC CCGCTTGTAC 
TTCCTGCTGG CCTGGTTTCA TGCGATCATC CAAGAACGCT TACGATACGC ACCACTGGGG 
TGGTCAAAGA AGTATGAATT TGGAGAGTCT GACCTGCGGT CAGCTTGCGA TACGGTGGAC 
ACGTGGCTGG ATGACACGGC CAAGGGCAGG CAGAACATCT CACCGGATAA GATCCCGTGG 
TCTGCACTAA AGACCTTAAT GGCCCAGTCC ATTTATGGCG GGCGCGTGGA CAACGAGTTT 
GACCAGCGTC TGCTCAACAC CTTCCTGGAG CGCCTGTTCA CAACCAGGAG TTTCGACAGT 
GAGTTTAAGC TGGCATGCAA GGTCGACGGA CATAAAGACA TTCAAATGCC AGATGGCATC 
AGGCGAGAGG AGTTTGTGCA GTGGGTGGAG TTGCTCCCCG ACACCCAGAC GCCCTCCTGG 
CTGGGCCTGC CCAACAACGC CGAGAGAGTC CTCCTTACCA CACAGGGTGT GGACATGATC 
AGTAAAATGC TGAAGATGCA GATGTTGGAG GATGAGGACG ACCTGGCCTA CGCAGAGACT 
GAGAAGAAGA CGAGGACAGA CTCCACGTCC GACGGGCGCC CTGCCTGGAT GCGGACACTG 
CACACCACCG CGTCCAACTG GCTGCACCTC ATCCCCCAGA CGCTGAGCCA CCTCAAGCGC 
ACCGTGGAGA ATATCAAGGA TCCTTTGTTC AGGTTCTTTG AGAGAGAAGT GAAGATGGGC 
GCAAAGCTGC TTCAGGACGT TCGCCAGGAC CTTGCAGATG TCGTCCAGGT GTGCGAAGGA 
AAGAAGAAGC AGACCAACTA CTTGCGCACG CTGATCAACG AGCTAGTGAA AGGGATCTTG 
CCTCGGAGCT GGTCCCACTA CACGGTGCCT GCCGGCATGA CCGTCATCCA GTGGGTGTCC 
GACTTCAGCG AGAGGATCAA ACAGCTGCAG AACATCTCAC TGGCAGCTGC ATCTGGTGGC 
GCCAAGGAGC TAAAGAACAT CCACGTGTGC CTGGGTGGCC TGTTCGTGCC TGAGGCGTAC 
ATCACTGCCA CCAGGCAGTA TGTGGCCCAG GCCAACAGCT GGTCCCTGGA GGAGCTCTGC 
CTGGAAGTCA ACGTCACCAC CTCACAGGGC GCCACCCTTG ACGCTTGCAG CTTCGGAGTC 
ACGGGTTTGA AACTTCAAGG GGCCACGTGC AACAACAACA AGCTGTCACT GTCCAATGCC 
ATCTCAACCG CCCTTCCCCT GACGCAGCTG CGCTGGGTCA AGCAGACAAA CACCGAGAAG 
AAGGCCAGTG TGGTAACCTT ACCTGTCTAC CTGAACTTCA CCCGTGCAGA CCTCATCTTC 
ACCGTGGACT TCGAAATTGC TACAAAGGAG GATCCTCGCA GCTTCTACGA GCGGGGTGTC 
GCAGTCTTGT GCACAGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001367.2
CDS	120..14060
Translation	MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKSALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE

Target ORF information:

RefSeq Version	NM_001376.5
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein cytoplasmic 1 heavy chain 1 (DYNC1H1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001376.5

ORF Insert Sequence:

ATGTCGGAGC CCGGGGGCGG CGGCGGCGAG GACGGCTCGG CCGGATTGGA AGTGTCGGCC 
GTGCAGAATG TGGCGGACGT GTCGGTGCTG CAGAAGCACC TGCGCAAGCT GGTGCCGCTG 
CTGCTGGAGG ACGGCGGCGA GGCGCCGGCC GCGCTGGAGG CGGCGCTGGA GGAGAAGAGC 
GCCCTGGAGC AGATGCGCAA GTTCCTTTCG GACCCGCAGG TCCACACGGT GCTGGTGGAG 
CGCTCCACGC TCAAAGAGGA CGTCGGTGAT GAAGGAGAAG AAGAAAAAGA ATTCATTTCC 
TATAACATCA ACATAGACAT TCATTATGGG GTTAAATCCA ATAGCTTGGC ATTCATTAAA 
CGTACTCCCG TGATTGATGC AGATAAACCC GTGTCTTCTC AGCTCCGGGT CCTTACACTC 
AGTGAAGACT CGCCCTACGA AACTTTGCAT TCTTTCATTA GCAATGCAGT GGCTCCTTTT 
TTTAAGTCCT ACATTAGAGA GTCTGGCAAG GCAGACAGGG ATGGTGATAA AATGGCTCCT 
TCAGTTGAAA AGAAGATTGC AGAACTCGAA ATGGGACTCC TTCACTTGCA GCAAAATATT 
GAAATTCCGG AGATCAGCCT GCCGATTCAT CCAATGATCA CAAATGTTGC AAAACAGTGT 
TATGAGCGTG GAGAAAAGCC AAAAGTTACA GACTTTGGTG ATAAGGTTGA AGACCCAACA 
TTTCTTAATC AGTTACAATC TGGAGTTAAC CGCTGGATCC GAGAAATTCA AAAAGTGACC 
AAACTGGATC GAGATCCTGC ATCAGGAACT GCCTTACAGG AAATTAGTTT TTGGCTAAAC 
TTGGAACGTG CGTTATACCG CATCCAGGAG AAACGGGAGA GCCCGGAAGT TCTCCTGACT 
CTGGATATCT TGAAACATGG CAAGCGCTTC CATGCCACCG TCAGTTTTGA CACTGACACA 
GGTCTAAAAC AGGCTTTGGA AACTGTGAAT GACTACAATC CTCTGATGAA AGATTTCCCT 
CTGAATGATT TGCTGTCTGC CACGGAGCTG GACAAAATAA GACAGGCGCT TGTTGCCATT 
TTCACACATT TGAGAAAGAT CCGAAACACA AAATATCCTA TTCAGAGGGC ACTGCGTTTG 
GTGGAGGCAA TTTCAAGAGA CTTGAGTTCT CAATTACTCA AAGTATTGGG CACTAGGAAA 
TTGATGCATG TTGCTTATGA AGAATTTGAA AAAGTTATGG TAGCATGCTT TGAAGTTTTT 
CAGACTTGGG ATGATGAGTA TGAGAAACTT CAGGTATTGT TGAGAGACAT CGTCAAAAGA 
AAAAGGGAAG AAAATCTGAA GATGGTGTGG CGTATCAACC CTGCCCACAG GAAGCTGCAG 
GCCCGCCTTG ACCAGATGAG AAAATTTAGA CGCCAGCATG AACAGCTAAG AGCTGTTATC 
GTCAGGGTCC TGAGGCCACA GGTCACGGCA GTTGCACAAC AGAATCAAGG AGAGGTCCCT 
GAACCCCAAG ATATGAAAGT GGCTGAGGTT CTCTTTGATG CTGCAGATGC AAATGCCATT 
GAGGAAGTAA ACCTTGCTTA TGAGAACGTC AAGGAAGTGG ATGGACTGGA TGTTTCCAAA 
GAGGGCACGG AAGCCTGGGA GGCTGCTATG AAGAGGTACG ATGAGAGGAT CGACAGAGTG 
GAGACCCGGA TCACCGCTCG CCTTCGGGAT CAGCTTGGCA CAGCCAAGAA TGCCAACGAG 
ATGTTTAGGA TTTTCTCCAG GTTTAATGCA CTGTTTGTCA GGCCTCACAT CCGTGGGGCC 
ATTCGCGAAT ACCAGACCCA GCTGATCCAG CGCGTGAAAG ATGACATTGA GTCTCTTCAC 
GACAAGTTCA AGGTCCAGTA CCCACAGAGT CAGGCTTGTA AGATGAGTCA CGTTCGTGAC 
TTGCCCCCTG TGTCAGGGTC TATCATCTGG GCTAAACAGA TCGACAGGCA GCTGACGGCC 
TACATGAAGC GGGTGGAAGA TGTCCTTGGC AAGGGCTGGG AGAATCACGT GGAGGGGCAG 
AAGCTGAAGC AGGATGGAGA CAGCTTCCGC ATGAAGCTCA ACACGCAGGA GATCTTTGAT 
GACTGGGCAA GGAAGGTGCA GCAGCGCAAC CTCGGTGTCT CGGGGCGCAT TTTCACCATC 
GAAAGTACTC GGGTTCGGGG CCGAACTGGA AATGTGCTTA AGCTGAAAGT TAACTTTCTT 
CCTGAGATTA TCACACTATC CAAAGAAGTC CGGAACCTCA AATGGCTTGG TTTCCGCGTC 
CCACTGGCGA TTGTGAACAA AGCCCATCAA GCAAACCAGC TTTACCCGTT TGCCATCTCA 
CTGATCGAGA GCGTTCGTAC CTATGAACGG ACCTGCGAGA AGGTGGAGGA GCGGAACACC 
ATTTCCCTTT TGGTGGCTGG CTTGAAAAAG GAAGTGCAGG CCCTGATCGC AGAAGGCATT 
GCGTTGGTGT GGGAGTCCTA CAAACTTGAC CCATATGTAC AGCGCTTAGC AGAGACTGTC 
TTCAACTTCC AAGAAAAGGT GGATGATCTG CTGATCATTG AAGAAAAAAT AGACCTAGAA 
GTCCGTTCCT TGGAAACTTG TATGTATGAC CATAAGACAT TCTCGGAAAT CTTGAACAGA 
GTCCAGAAAG CAGTGGATGA CTTAAATCTG CACTCCTATT CCAATTTGCC CATCTGGGTC 
AACAAGCTTG ACATGGAGAT TGAAAGAATA TTGGGCGTCC GTCTGCAAGC TGGCCTGAGA 
GCTTGGACGC AGGTTCTTCT TGGACAAGCT GAAGATAAAG CAGAAGTTGA CATGGACACA 
GATGCTCCAC AAGTTAGTCA CAAGCCTGGT GGAGAGCCAA AGATCAAAAA TGTCGTTCAT 
GAGCTAAGAA TAACCAATCA GGTAATCTAC TTGAATCCAC CAATTGAAGA GTGCAGATAC 
AAGCTGTATC AGGAAATGTT TGCCTGGAAG ATGGTTGTAC TGTCTCTCCC CAGGATCCAG 
AGTCAGAGGT ACCAGGTGGG TGTACATTAC GAATTGACTG AGGAAGAGAA ATTCTATCGG 
AATGCTTTAA CACGGATGCC TGATGGCCCT GTTGCCCTGG AAGAGTCGTA TTCTGCTGTC 
ATGGGCATTG TATCTGAAGT TGAACAGTAT GTCAAGGTTT GGCTTCAGTA TCAGTGTTTA 
TGGGATATGC AAGCTGAAAA CATCTATAAC AGACTTGGAG AAGATCTCAA CAAATGGCAG 
GCTCTCCTGG TCCAAATAAG GAAGGCCAGA GGAACCTTTG ACAATGCAGA AACCAAGAAA 
GAGTTTGGAC CAGTAGTTAT AGATTATGGC AAGGTACAAT CTAAGGTGAA CTTGAAATAT 
GACTCTTGGC ATAAGGAGGT TCTTAGCAAA TTTGGGCAGA TGCTAGGATC AAACATGACG 
GAATTCCATT CCCAGATCTC AAAGTCCCGC CAAGAGTTGG AGCAGCACTC AGTAGACACG 
GCCAGCACCT CCGATGCAGT GACCTTCATC ACCTATGTGC AGTCTTTGAA ACGGAAGATC 
AAGCAGTTTG AGAAGCAAGT TGAGCTCTAC CGCAATGGCC AGCGCTTACT GGAAAAGCAA 
AGGTTCCAGT TCCCACCTTC CTGGCTTTAT ATTGACAACA TCGAGGGAGA GTGGGGAGCC 
TTCAATGACA TCATGCGGCG AAAGGACTCT GCCATTCAGC AGCAGGTGGC AAACCTGCAA 
ATGAAGATTG TCCAGGAGGA TCGGGCCGTG GAAAGCCGCA CCACCGACCT GCTGACTGAC 
TGGGAGAAGA CCAAGCCTGT CACGGGCAAC CTTCGCCCAG AAGAGGCACT TCAGGCTCTC 
ACCATATATG AGGGGAAGTT TGGTAGGCTG AAGGACGACA GAGAGAAGTG TGCAAAGGCC 
AAGGAGGCGC TGGAATTGAC AGATACTGGG CTTCTCAGTG GCAGTGAAGA GCGCGTGCAG 
GTGGCCTTAG AAGAATTACA GGACCTCAAA GGCGTTTGGT CAGAACTTTC TAAGGTTTGG 
GAGCAAATCG ATCAGATGAA GGAGCAACCC TGGGTTTCAG TACAGCCTCG AAAGCTTCGA 
CAAAATTTGG ATGCCCTCCT GAACCAGCTG AAAAGCTTCC CTGCCCGGTT GCGACAGTAT 
GCGTCCTATG AGTTTGTTCA GAGGCTTCTG AAAGGTTACA TGAAGATAAA TATGCTGGTG 
ATTGAACTGA AATCCGAAGC ACTTAAAGAC CGCCATTGGA AACAGCTCAT GAAAAGGCTT 
CACGTTAATT GGGTTGTTTC TGAGCTAACC CTTGGCCAAA TCTGGGATGT TGACTTGCAG 
AAAAATGAAG CGATTGTCAA GGATGTACTG CTTGTGGCAC AAGGGGAGAT GGCTTTGGAA 
GAATTTTTGA AGCAGATAAG AGAAGTGTGG AATACTTATG AACTAGACTT GGTTAATTAT 
CAGAACAAGT GCCGCTTGAT CCGTGGCTGG GATGACCTCT TCAACAAGGT CAAAGAACAC 
ATCAACAGCG TCTCGGCCAT GAAGCTCTCT CCGTATTACA AGGTTTTTGA AGAGGATGCT 
CTCAGCTGGG AAGATAAGCT GAACAGGATC ATGGCTCTCT TTGATGTGTG GATTGATGTG 
CAGAGGCGGT GGGTCTACCT GGAAGGTATC TTCACAGGCA GTGCAGATAT CAAGCACCTG 
CTGCCAGTGG AAACCCAGCG GTTTCAGAGC ATCAGCACTG AGTTTTTGGC TCTAATGAAA 
AAAGTGTCCA AGTCTCCCCT TGTTATGGAT GTTCTGAACA TCCAGGGAGT ACAGAGGTCT 
CTGGAAAGAT TGGCAGACCT GCTAGGAAAG ATCCAGAAAG CATTGGGAGA ATATCTGGAA 
AGAGAGCGGT CATCTTTCCC CAGGTTCTAT TTTGTGGGTG ATGAAGATTT GCTTGAAATC 
ATTGGAAACA GCAAGAATGT CGCTAAATTA CAGAAACACT TCAAGAAGAT GTTTGCTGGA 
GTTTCGAGCA TCATCCTGAA CGAGGATAAC TCTGTTGTTT TGGGTATTTC ATCTCGGGAA 
GGAGAGGAGG TTATGTTTAA AACTCCTGTG TCAATTACTG AACATCCCAA AATCAATGAG 
TGGCTCACAT TGGTAGAAAA GGAGATGAGA GTCACCCTGG CCAAACTGCT TGCTGAGTCT 
GTTACGGAAG TTGAGATTTT TGGTAAAGCA ACTTCAATTG ACCCAAATAC CTACATCACT 
TGGATTGATA AATACCAGGC CCAGCTTGTG GTTTTGTCAG CCCAGATAGC CTGGTCTGAG 
AACGTGGAGA CCGCACTGAG CAGCATGGGC GGAGGTGGAG ATGCCGCGCC CTTGCACTCT 
GTGCTGAGCA ATGTGGAGGT CACCCTCAAT GTGTTAGCAG ACTCTGTCCT CATGGAGCAG 
CCCCCACTCC GAAGGCGGAA GCTAGAACAC TTGATTACAG AGTTGGTTCA CCAGAGAGAT 
GTTACAAGGT CCTTGATCAA AAGCAAGATT GACAACGCCA AATCTTTTGA ATGGCTCAGC 
CAGATGCGAT TTTACTTTGA CCCTAAGCAA ACTGATGTGT TACAGCAGTT GTCAATTCAA 
ATGGCAAATG CCAAATTTAA CTATGGCTTT GAGTACCTGG GTGTTCAGGA CAAACTGGTC 
CAGACCCCCC TCACTGACCG CTGCTATTTG ACAATGACAC AAGCCTTGGA GGCCAGGCTG 
GGGGGTTCCC CATTTGGACC TGCTGGAACT GGGAAAACAG AGTCTGTCAA AGCTCTTGGC 
CATCAGCTTG GACGGTTTGT TTTAGTTTTC AACTGTGATG AAACCTTTGA TTTCCAGGCA 
ATGGGCCGGA TCTTTGTGGG CCTTTGCCAG GTGGGTGCCT GGGGCTGCTT TGACGAGTTC 
AACCGCCTGG AGGAGCGGAT GCTCTCGGCT GTGTCCCAGC AGGTGCAGTG CATACAGGAA 
GCACTGCGTG AACATTCCAA CCCCAACTAC GACAAGACCT CTGCCCCCAT TACTTGTGAG 
CTGCTGAACA AACAAGTCAA GGTGAGCCCG GACATGGCCA TCTTCATCAC CATGAACCCT 
GGCTACGCGG GCCGGTCTAA CCTTCCTGAC AACTTGAAGA AGCTGTTCCG GAGCTTGGCC 
ATGACCAAGC CCGACCGGCA GTTAATCGCC CAGGTCATGC TGTACTCACA GGGTTTCCGC 
ACTGCTGAAG TGCTTGCCAA CAAAATCGTC CCGTTTTTTA AACTATGCGA TGAGCAGCTC 
TCTTCCCAAA GCCATTATGA CTTCGGTCTT CGGGCTTTGA AGAGTGTGCT GGTGAGTGCA 
GGCAATGTGA AGAGAGAGAG AATCCAGAAG ATAAAGAGGG AGAAAGAGGA ACGAGGGGAA 
GCAGTTGATG AAGGAGAAAT TGCTGAAAAT CTCCCTGAAC AAGAGATTCT GATACAGAGC 
GTCTGTGAGA CGATGGTGCC AAAGCTGGTG GCAGAGGACA TCCCGCTGCT CTTCAGCCTC 
CTGTCGGACG TGTTCCCTGG AGTCCAGTAT CACAGGGGTG AGATGACTGC CCTTCGAGAG 
GAGCTGAAGA AAGTGTGTCA GGAGATGTAT TTGACATATG GAGATGGAGA AGAAGTTGGT 
GGAATGTGGG TTGAAAAGGT TCTCCAGCTC TATCAGATCA CCCAGATCAA TCATGGCCTG 
ATGATGGTGG GGCCCTCGGG AAGTGGGAAG AGCATGGCCT GGCGTGTCCT GCTGAAGGCA 
TTGGAGAGAC TCGAGGGTGT GGAAGGTGTG GCCCATATCA TCGACCCCAA GGCCATCAGC 
AAAGACCACC TCTACGGAAC CCTGGACCCC AACACCAGGG AATGGACAGA TGGGCTCTTC 
ACACACGTGC TGAGAAAGAT CATCGACAGC GTGAGAGGCG AGCTGCAGAA GCGCCAGTGG 
ATCGTCTTCG ATGGCGATGT GGATCCAGAG TGGGTTGAGA ACTTGAACTC AGTGCTGGAT 
GACAATAAGC TCCTAACTTT GCCCAATGGA GAGCGCCTCA GTCTTCCACC CAATGTGAGA 
ATAATGTTTG AGGTACAGGA CTTGAAATAC GCGACCTTGG CCACAGTGTC GCGCTGCGGC 
ATGGTCTGGT TCAGTGAGGA TGTGCTGAGC ACCGACATGA TCTTCAACAA CTTCCTGGCC 
AGGCTGCGCA GCATCCCGCT GGATGAAGGG GAGGATGAGG CACAGCGGCG GCGTAAGGGC 
AAAGAGGATG AGGGGGAGGA GGCCGCTTCC CCCATGCTGC AGATCCAAAG AGATGCAGCT 
ACGATCATGC AACCGTACTT CACGTCCAAC GGCCTGGTCA CCAAGGCGCT AGAGCACGCC 
TTCCAGCTGG AGCACATCAT GGACCTAACA CGCCTGCGCT GCCTGGGCTC GCTCTTCTCC 
ATGCTGCACC AGGCCTGCCG CAACGTGGCG CAGTATAACG CCAACCATCC CGACTTCCCC 
ATGCAGATCG AGCAGCTGGA GCGCTACATT CAGCGATATC TGGTTTATGC CATACTCTGG 
TCCCTGTCTG GAGACAGCCG GCTAAAAATG AGAGCAGAGC TGGGTGAATA CATCAGAAGA 
ATCACGACCG TGCCTCTGCC CACTGCGCCC AACATACCCA TTATCGATTA TGAGGTGTCC 
ATCAGCGGAG AATGGTCTCC GTGGCAGGCC AAGGTGCCTC AGATTGAAGT GGAGACGCAC 
AAGGTGGCAG CCCCTGATGT CGTCGTGCCA ACGCTGGACA CAGTCCGCCA CGAAGCCCTC 
TTGTACACTT GGCTGGCCGA ACACAAGCCC CTGGTCTTGT GTGGCCCTCC TGGGTCTGGC 
AAGACCATGA CACTCTTCAG CGCCCTCCGG GCCTTGCCTG ACATGGAGGT GGTGGGTCTC 
AACTTCTCCA GTGCTACTAC TCCAGAGCTG CTTCTGAAGA CTTTTGATCA CTACTGCGAG 
TACAGGCGCA CACCTAATGG GGTGGTTTTG GCTCCTGTTC AACTTGGAAA GTGGCTGGTG 
TTGTTCTGTG ATGAAATCAA CTTGCCAGAT ATGGATAAAT ATGGGACCCA GAGGGTCATA 
TCCTTCATCA GACAGATGGT GGAGCACGGA GGCTTTTACC GTACCTCAGA TCAAACATGG 
GTGAAGCTGG AGAGAATCCA GTTTGTTGGG GCTTGTAATC CCCCCACAGA CCCTGGAAGA 
AAGCCCCTCT CACACAGGTT CCTGCGCCAC GTGCCTGTCG TGTATGTGGA TTACCCGGGC 
CCCGCCTCCC TCACACAGAT CTACGGCACC TTCAACCGCG CCATGCTGAG GCTCATTCCA 
TCCCTGCGGA CGTATGCAGA GCCGCTCACT GCTGCCATGG TGGAGTTCTA CACCATGTCT 
CAGGAGAGAT TCACCCAGGA TACACAACCT CACTATATCT ATTCACCCCG TGAAATGACT 
AGGTGGGTGA GAGGCATCTT TGAAGCGCTG AGACCTCTGG AGACCCTGCC TGTTGAAGGC 
CTCATTCGGA TTTGGGCACA TGAAGCTCTG CGTCTCTTCC AAGATAGACT CGTAGAGGAT 
GAGGAGAGGC GTTGGACTGA TGAGAACATC GACACGGTTG CTCTGAAGCA CTTCCCTAAC 
ATCGACAGAG AGAAGGCAAT GAGCCGACCC ATCTTGTACA GCAACTGGCT GTCAAAGGAT 
TACATCCCAG TAGACCAAGA AGAGTTAAGA GATTATGTCA AAGCTAGGCT GAAGGTCTTT 
TATGAAGAAG AACTTGATGT TCCGCTGGTG CTGTTTAATG AAGTCCTAGA CCACGTGCTG 
AGGATTGACA GAATATTCCG TCAACCTCAA GGCCACTTGC TTCTGATTGG TGTTAGTGGA 
GCAGGAAAAA CTACCCTGTC TCGTTTCGTC GCCTGGATGA ACGGTTTGAG TGTGTACCAG 
ATTAAGGTCC ATAGGAAGTA CACAGGGGAA GACTTTGATG AAGATCTACG GACAGTGTTG 
AGACGTTCTG GCTGTAAAAA TGAAAAGATA GCATTTATAA TGGATGAATC TAATGTGTTA 
GATTCTGGAT TCCTGGAGCG AATGAATACC CTTCTGGCCA ATGGAGAGGT GCCTGGTCTC 
TTTGAAGGAG ACGAGTATGC CACCTTGATG ACGCAGTGCA AAGAGGGGGC ACAGAAGGAA 
GGCCTGATGC TGGACTCGCA CGAGGAGCTC TACAAGTGGT TCACTAGCCA GGTTATCCGC 
AACCTCCACG TCGTGTTCAC CATGAACCCG TCCTCGGAGG GACTCAAGGA CCGGGCAGCT 
ACATCACCAG CACTTTTCAA CAGGTGTGTG TTGAATTGGT TTGGAGACTG GTCCACCGAA 
GCACTGTATC AGGTTGGCAA AGAATTCACA AGTAAGATGG ATCTGGAGAA GCCAAATTAC 
ATCGTGCCTG ATTACATGCC AGTTGTGTAT GATAAGCTGC CGCAGCCACC ATCCCATCGG 
GAAGCCATTG TGAACAGCTG TGTGTTTGTT CATCAGACTC TTCACCAGGC GAATGCTCGG 
CTAGCAAAGC GAGGCGGCAG AACGATGGCC ATCACCCCTC GCCACTACCT GGACTTCATC 
AATCACTATG CCAACCTGTT CCACGAGAAG CGGAGCGAGC TGGAGGAGCA GCAGATGCAC 
TTGAACGTGG GGCTCAGGAA GATCAAAGAG ACAGTCGACC AGGTAGAAGA ACTGCGTCGT 
GACTTGAGGA TAAAGAGCCA AGAGCTGGAG GTGAAGAATG CAGCAGCCAA TGACAAGCTG 
AAAAAGATGG TGAAAGACCA GCAGGAGGCT GAAAAGAAGA AGGTTATGAG CCAAGAAATC 
CAGGAACAGC TGCATAAGCA GCAGGAGGTA ATTGCAGACA AACAGATGAG TGTCAAAGAA 
GATCTTGATA AGGTGGAACC TGCCGTCATT GAGGCCCAGA ATGCTGTGAA GTCGATCAAG 
AAGCAGCACC TGGTGGAGGT GAGGTCCATG GCCAACCCTC CTGCTGCTGT GAAGCTGGCG 
CTGGAGTCCA TCTGCCTGCT GCTGGGGGAA AGCACCACAG ACTGGAAGCA GATCCGCTCC 
ATCATCATGC GGGAGAACTT CATCCCCACC ATCGTCAACT TCTCTGCAGA GGAGATCAGT 
GACGCCATAA GGGAGAAGAT GAAGAAAAAT TACATGTCCA ATCCAAGTTA CAATTATGAA 
ATTGTGAATC GGGCTTCCCT GGCTTGCGGC CCTATGGTGA AATGGGCAAT TGCACAGCTT 
AACTATGCAG ACATGTTAAA GAGAGTGGAG CCCCTACGCA ATGAGCTGCA GAAGCTGGAA 
GATGACGCCA AGGACAACCA GCAGAAGGCC AACGAGGTGG AGCAGATGAT CCGAGACCTG 
GAAGCCAGCA TCGCCCGCTA CAAGGAGGAA TACGCCGTCC TGATCTCAGA GGCCCAGGCC 
ATCAAGGCAG ACCTGGCAGC TGTCGAGGCA AAAGTAAACC GGAGCACTGC TCTTCTGAAG 
AGCTTGTCTG CTGAACGTGA ACGATGGGAA AAAACAAGTG AAACTTTCAA AAACCAGATG 
TCCACCATTG CTGGGGACTG TCTCTTGTCA GCTGCGTTCA TTGCCTACGC GGGTTACTTT 
GACCAGCAGA TGCGTCAGAA CTTGTTCACT ACCTGGTCCC ATCACCTACA GCAAGCCAAC 
ATCCAGTTCC GTACAGATAT TGCCAGGACG GAATACCTTT CCAATGCTGA TGAGCGTCTT 
CGCTGGCAGG CCAGCTCCTT GCCTGCTGAT GACCTTTGCA CAGAAAATGC CATCATGCTG 
AAACGATTCA ATAGGTATCC GCTGATCATT GACCCCTCTG GACAGGCCAC AGAATTCATT 
ATGAATGAAT ATAAGGATCG TAAGATCACA CGGACCAGCT TCCTGGATGA CGCCTTCAGA 
AAGAACTTAG AGAGTGCACT GAGATTCGGT AACCCCCTTC TGGTCCAGGA TGTGGAAAGC 
TACGATCCAG TTTTGAACCC GGTGCTGAAC CGTGAAGTGC GGCGAACAGG GGGGAGAGTG 
CTGATCACTC TCGGGGACCA GGACATAGAC CTGTCGCCAT CGTTTGTCAT CTTCCTGTCC 
ACCCGGGATC CAACTGTCGA GTTCCCACCA GATCTCTGTT CCCGGGTTAC TTTTGTAAAC 
TTCACAGTTA CCCGTAGCAG TTTACAAAGC CAGTGTCTAA ATGAAGTACT TAAAGCAGAA 
AGACCTGATG TGGACGAGAA ACGATCTGAT CTTCTTAAAC TTCAAGGGGA ATTTCAGCTC 
CGTTTGCGTC AGCTGGAAAA ATCTCTACTA CAAGCTCTGA ACGAGGTGAA AGGGCGCATT 
TTGGATGACG ACACGATCAT AACCACTCTG GAGAACCTGA AGAGAGAGGC TGCAGAGGTC 
ACCAGGAAAG TTGAGGAGAC GGACATTGTC ATGCAGGAGG TGGAGACCGT GTCCCAGCAG 
TACCTCCCGC TCTCCACCGC CTGCAGCAGC ATCTACTTCA CCATGGAGTC CCTCAAGCAG 
ATACACTTCT TGTACCAGTA CTCCCTCCAG TTTTTCCTGG ACATTTATCA CAACGTCCTA 
TACGAGAACC CGAACCTGAA GGGTGTCACC GACCACACAC AGCGCCTGTC CATTATAACA 
AAGGACCTCT TCCAGGTGGC GTTTAACCGA GTGGCTCGAG GCATGCTGCA TCAGGACCAC 
ATTACCTTTG CCATGCTGCT GGCAAGAATC AAACTGAAGG GCACCGTGGG GGAGCCCACC 
TACGATGCAG AATTCCAGCA CTTCTTGAGA GGAAATGAGA TTGTCCTGAG TGCTGGCTCC 
ACCCCCAGGA TCCAGGGCCT GACTGTGGAG CAGGCGGAGG CGGTGGTGAG GCTGAGCTGC 
CTTCCCGCGT TTAAGGACTT GATTGCAAAG GTTCAGGCAG ACGAGCAATT TGGCATCTGG 
CTGGACAGCA GCTCCCCGGA GCAGACTGTG CCCTACCTCT GGAGTGAAGA AACACCTGCA 
ACACCCATTG GCCAGGCCAT CCACCGCCTG CTCCTGATCC AGGCTTTCCG GCCCGATCGC 
CTGTTGGCCA TGGCCCACAT GTTTGTTTCA ACAAACCTTG GGGAGTCTTT CATGTCCATC 
ATGGAGCAGC CGCTCGACCT GACCCACATT GTGGGCACAG AGGTGAAGCC CAACACTCCT 
GTCTTAATGT GCTCTGTGCC TGGTTATGAT GCCAGTGGAC ATGTCGAGGA CCTTGCAGCC 
GAGCAGAACA CGCAGATCAC TTCAATTGCA ATCGGCTCTG CAGAAGGCTT TAACCAAGCA 
GATAAGGCAA TAAACACCGC TGTAAAGTCG GGCAGGTGGG TGATGCTGAA GAATGTGCAT 
CTGGCCCCAG GGTGGCTGAT GCAGCTGGAG AAGAAGTTGC ATTCCCTGCA GCCGCATGCC 
TGCTTCCGAC TCTTCCTCAC CATGGAGATC AACCCCAAGG TGCCTGTGAA TCTGCTCCGT 
GCGGGCCGCA TCTTTGTGTT CGAGCCACCG CCAGGGGTGA AGGCCAACAT GCTGAGGACG 
TTCAGCAGCA TTCCCGTCTC ACGGATATGC AAGTCTCCCA ACGAGCGTGC CCGCTTGTAC 
TTCCTGCTGG CCTGGTTTCA TGCGATCATC CAAGAACGCT TACGATACGC ACCACTGGGG 
TGGTCAAAGA AGTATGAATT TGGAGAGTCT GACCTGCGGT CAGCTTGCGA TACGGTGGAC 
ACGTGGCTGG ATGACACGGC CAAGGGCAGG CAGAACATCT CACCGGATAA GATCCCGTGG 
TCTGCACTAA AGACCTTAAT GGCCCAGTCC ATTTATGGCG GGCGCGTGGA CAACGAGTTT 
GACCAGCGTC TGCTCAACAC CTTCCTGGAG CGCCTGTTCA CAACCAGGAG TTTCGACAGT 
GAGTTTAAGC TGGCATGCAA GGTCGACGGA CATAAAGACA TTCAAATGCC AGATGGCATC 
AGGCGAGAGG AGTTTGTGCA GTGGGTGGAG TTGCTCCCCG ACACCCAGAC GCCCTCCTGG 
CTGGGCCTGC CCAACAACGC CGAGAGAGTC CTCCTTACCA CACAGGGTGT GGACATGATC 
AGTAAAATGC TGAAGATGCA GATGTTGGAG GATGAGGACG ACCTGGCCTA CGCAGAGACT 
GAGAAGAAGA CGAGGACAGA CTCCACGTCC GACGGGCGCC CTGCCTGGAT GCGGACACTG 
CACACCACCG CGTCCAACTG GCTGCACCTC ATCCCCCAGA CGCTGAGCCA CCTCAAGCGC 
ACCGTGGAGA ATATCAAGGA TCCTTTGTTC AGGTTCTTTG AGAGAGAAGT GAAGATGGGC 
GCAAAGCTGC TTCAGGACGT TCGCCAGGAC CTTGCAGATG TCGTCCAGGT GTGCGAAGGA 
AAGAAGAAGC AGACCAACTA CTTGCGCACG CTGATCAACG AGCTAGTGAA AGGGATCTTG 
CCTCGGAGCT GGTCCCACTA CACGGTGCCT GCCGGCATGA CCGTCATCCA GTGGGTGTCC 
GACTTCAGCG AGAGGATCAA ACAGCTGCAG AACATCTCAC TGGCAGCTGC ATCTGGTGGC 
GCCAAGGAGC TAAAGAACAT CCACGTGTGC CTGGGTGGCC TGTTCGTGCC TGAGGCGTAC 
ATCACTGCCA CCAGGCAGTA TGTGGCCCAG GCCAACAGCT GGTCCCTGGA GGAGCTCTGC 
CTGGAAGTCA ACGTCACCAC CTCACAGGGC GCCACCCTTG ACGCTTGCAG CTTCGGAGTC 
ACGGGTTTGA AACTTCAAGG GGCCACGTGC AACAACAACA AGCTGTCACT GTCCAATGCC 
ATCTCAACCG CCCTTCCCCT GACGCAGCTG CGCTGGGTCA AGCAGACAAA CACCGAGAAG 
AAGGCCAGTG TGGTAACCTT ACCTGTCTAC CTGAACTTCA CCCGTGCAGA CCTCATCTTC 
ACCGTGGACT TCGAAATTGC TACAAAGGAG GATCCTCGCA GCTTCTACGA GCGGGGTGTC 
GCAGTCTTGT GCACAGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DYNC1H1 ( NM_001376.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001367.2 Homo sapiens dynein cytoplasmic 1 heavy chain 1 (DYNC1H1), mRNA.

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CloneID	OHu26236
Clone ID Related Accession (Same CDS sequence)	NM_001376.5 , NM_001376.4
Accession Version	NM_001376.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 13941bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	cytoplasmic dynein 1 heavy chain 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB290157.1, AB002323.3 and DB508175.2. This sequence is a reference standard in the RefSeqGene project. On Oct 11, 2008 this sequence version replaced NM_001376.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB290157.1, AB002323.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGAGC CCGGGGGCGG CGGCGGCGAG GACGGCTCGG CCGGATTGGA AGTGTCGGCC 
GTGCAGAATG TGGCGGACGT GTCGGTGCTG CAGAAGCACC TGCGCAAGCT GGTGCCGCTG 
CTGCTGGAGG ACGGCGGCGA GGCGCCGGCC GCGCTGGAGG CGGCGCTGGA GGAGAAGAGC 
GCCCTGGAGC AGATGCGCAA GTTCCTTTCG GACCCGCAGG TCCACACGGT GCTGGTGGAG 
CGCTCCACGC TCAAAGAGGA CGTCGGTGAT GAAGGAGAAG AAGAAAAAGA ATTCATTTCC 
TATAACATCA ACATAGACAT TCATTATGGG GTTAAATCCA ATAGCTTGGC ATTCATTAAA 
CGTACTCCCG TGATTGATGC AGATAAACCC GTGTCTTCTC AGCTCCGGGT CCTTACACTC 
AGTGAAGACT CGCCCTACGA AACTTTGCAT TCTTTCATTA GCAATGCAGT GGCTCCTTTT 
TTTAAGTCCT ACATTAGAGA GTCTGGCAAG GCAGACAGGG ATGGTGATAA AATGGCTCCT 
TCAGTTGAAA AGAAGATTGC AGAACTCGAA ATGGGACTCC TTCACTTGCA GCAAAATATT 
GAAATTCCGG AGATCAGCCT GCCGATTCAT CCAATGATCA CAAATGTTGC AAAACAGTGT 
TATGAGCGTG GAGAAAAGCC AAAAGTTACA GACTTTGGTG ATAAGGTTGA AGACCCAACA 
TTTCTTAATC AGTTACAATC TGGAGTTAAC CGCTGGATCC GAGAAATTCA AAAAGTGACC 
AAACTGGATC GAGATCCTGC ATCAGGAACT GCCTTACAGG AAATTAGTTT TTGGCTAAAC 
TTGGAACGTG CGTTATACCG CATCCAGGAG AAACGGGAGA GCCCGGAAGT TCTCCTGACT 
CTGGATATCT TGAAACATGG CAAGCGCTTC CATGCCACCG TCAGTTTTGA CACTGACACA 
GGTCTAAAAC AGGCTTTGGA AACTGTGAAT GACTACAATC CTCTGATGAA AGATTTCCCT 
CTGAATGATT TGCTGTCTGC CACGGAGCTG GACAAAATAA GACAGGCGCT TGTTGCCATT 
TTCACACATT TGAGAAAGAT CCGAAACACA AAATATCCTA TTCAGAGGGC ACTGCGTTTG 
GTGGAGGCAA TTTCAAGAGA CTTGAGTTCT CAATTACTCA AAGTATTGGG CACTAGGAAA 
TTGATGCATG TTGCTTATGA AGAATTTGAA AAAGTTATGG TAGCATGCTT TGAAGTTTTT 
CAGACTTGGG ATGATGAGTA TGAGAAACTT CAGGTATTGT TGAGAGACAT CGTCAAAAGA 
AAAAGGGAAG AAAATCTGAA GATGGTGTGG CGTATCAACC CTGCCCACAG GAAGCTGCAG 
GCCCGCCTTG ACCAGATGAG AAAATTTAGA CGCCAGCATG AACAGCTAAG AGCTGTTATC 
GTCAGGGTCC TGAGGCCACA GGTCACGGCA GTTGCACAAC AGAATCAAGG AGAGGTCCCT 
GAACCCCAAG ATATGAAAGT GGCTGAGGTT CTCTTTGATG CTGCAGATGC AAATGCCATT 
GAGGAAGTAA ACCTTGCTTA TGAGAACGTC AAGGAAGTGG ATGGACTGGA TGTTTCCAAA 
GAGGGCACGG AAGCCTGGGA GGCTGCTATG AAGAGGTACG ATGAGAGGAT CGACAGAGTG 
GAGACCCGGA TCACCGCTCG CCTTCGGGAT CAGCTTGGCA CAGCCAAGAA TGCCAACGAG 
ATGTTTAGGA TTTTCTCCAG GTTTAATGCA CTGTTTGTCA GGCCTCACAT CCGTGGGGCC 
ATTCGCGAAT ACCAGACCCA GCTGATCCAG CGCGTGAAAG ATGACATTGA GTCTCTTCAC 
GACAAGTTCA AGGTCCAGTA CCCACAGAGT CAGGCTTGTA AGATGAGTCA CGTTCGTGAC 
TTGCCCCCTG TGTCAGGGTC TATCATCTGG GCTAAACAGA TCGACAGGCA GCTGACGGCC 
TACATGAAGC GGGTGGAAGA TGTCCTTGGC AAGGGCTGGG AGAATCACGT GGAGGGGCAG 
AAGCTGAAGC AGGATGGAGA CAGCTTCCGC ATGAAGCTCA ACACGCAGGA GATCTTTGAT 
GACTGGGCAA GGAAGGTGCA GCAGCGCAAC CTCGGTGTCT CGGGGCGCAT TTTCACCATC 
GAAAGTACTC GGGTTCGGGG CCGAACTGGA AATGTGCTTA AGCTGAAAGT TAACTTTCTT 
CCTGAGATTA TCACACTATC CAAAGAAGTC CGGAACCTCA AATGGCTTGG TTTCCGCGTC 
CCACTGGCGA TTGTGAACAA AGCCCATCAA GCAAACCAGC TTTACCCGTT TGCCATCTCA 
CTGATCGAGA GCGTTCGTAC CTATGAACGG ACCTGCGAGA AGGTGGAGGA GCGGAACACC 
ATTTCCCTTT TGGTGGCTGG CTTGAAAAAG GAAGTGCAGG CCCTGATCGC AGAAGGCATT 
GCGTTGGTGT GGGAGTCCTA CAAACTTGAC CCATATGTAC AGCGCTTAGC AGAGACTGTC 
TTCAACTTCC AAGAAAAGGT GGATGATCTG CTGATCATTG AAGAAAAAAT AGACCTAGAA 
GTCCGTTCCT TGGAAACTTG TATGTATGAC CATAAGACAT TCTCGGAAAT CTTGAACAGA 
GTCCAGAAAG CAGTGGATGA CTTAAATCTG CACTCCTATT CCAATTTGCC CATCTGGGTC 
AACAAGCTTG ACATGGAGAT TGAAAGAATA TTGGGCGTCC GTCTGCAAGC TGGCCTGAGA 
GCTTGGACGC AGGTTCTTCT TGGACAAGCT GAAGATAAAG CAGAAGTTGA CATGGACACA 
GATGCTCCAC AAGTTAGTCA CAAGCCTGGT GGAGAGCCAA AGATCAAAAA TGTCGTTCAT 
GAGCTAAGAA TAACCAATCA GGTAATCTAC TTGAATCCAC CAATTGAAGA GTGCAGATAC 
AAGCTGTATC AGGAAATGTT TGCCTGGAAG ATGGTTGTAC TGTCTCTCCC CAGGATCCAG 
AGTCAGAGGT ACCAGGTGGG TGTACATTAC GAATTGACTG AGGAAGAGAA ATTCTATCGG 
AATGCTTTAA CACGGATGCC TGATGGCCCT GTTGCCCTGG AAGAGTCGTA TTCTGCTGTC 
ATGGGCATTG TATCTGAAGT TGAACAGTAT GTCAAGGTTT GGCTTCAGTA TCAGTGTTTA 
TGGGATATGC AAGCTGAAAA CATCTATAAC AGACTTGGAG AAGATCTCAA CAAATGGCAG 
GCTCTCCTGG TCCAAATAAG GAAGGCCAGA GGAACCTTTG ACAATGCAGA AACCAAGAAA 
GAGTTTGGAC CAGTAGTTAT AGATTATGGC AAGGTACAAT CTAAGGTGAA CTTGAAATAT 
GACTCTTGGC ATAAGGAGGT TCTTAGCAAA TTTGGGCAGA TGCTAGGATC AAACATGACG 
GAATTCCATT CCCAGATCTC AAAGTCCCGC CAAGAGTTGG AGCAGCACTC AGTAGACACG 
GCCAGCACCT CCGATGCAGT GACCTTCATC ACCTATGTGC AGTCTTTGAA ACGGAAGATC 
AAGCAGTTTG AGAAGCAAGT TGAGCTCTAC CGCAATGGCC AGCGCTTACT GGAAAAGCAA 
AGGTTCCAGT TCCCACCTTC CTGGCTTTAT ATTGACAACA TCGAGGGAGA GTGGGGAGCC 
TTCAATGACA TCATGCGGCG AAAGGACTCT GCCATTCAGC AGCAGGTGGC AAACCTGCAA 
ATGAAGATTG TCCAGGAGGA TCGGGCCGTG GAAAGCCGCA CCACCGACCT GCTGACTGAC 
TGGGAGAAGA CCAAGCCTGT CACGGGCAAC CTTCGCCCAG AAGAGGCACT TCAGGCTCTC 
ACCATATATG AGGGGAAGTT TGGTAGGCTG AAGGACGACA GAGAGAAGTG TGCAAAGGCC 
AAGGAGGCGC TGGAATTGAC AGATACTGGG CTTCTCAGTG GCAGTGAAGA GCGCGTGCAG 
GTGGCCTTAG AAGAATTACA GGACCTCAAA GGCGTTTGGT CAGAACTTTC TAAGGTTTGG 
GAGCAAATCG ATCAGATGAA GGAGCAACCC TGGGTTTCAG TACAGCCTCG AAAGCTTCGA 
CAAAATTTGG ATGCCCTCCT GAACCAGCTG AAAAGCTTCC CTGCCCGGTT GCGACAGTAT 
GCGTCCTATG AGTTTGTTCA GAGGCTTCTG AAAGGTTACA TGAAGATAAA TATGCTGGTG 
ATTGAACTGA AATCCGAAGC ACTTAAAGAC CGCCATTGGA AACAGCTCAT GAAAAGGCTT 
CACGTTAATT GGGTTGTTTC TGAGCTAACC CTTGGCCAAA TCTGGGATGT TGACTTGCAG 
AAAAATGAAG CGATTGTCAA GGATGTACTG CTTGTGGCAC AAGGGGAGAT GGCTTTGGAA 
GAATTTTTGA AGCAGATAAG AGAAGTGTGG AATACTTATG AACTAGACTT GGTTAATTAT 
CAGAACAAGT GCCGCTTGAT CCGTGGCTGG GATGACCTCT TCAACAAGGT CAAAGAACAC 
ATCAACAGCG TCTCGGCCAT GAAGCTCTCT CCGTATTACA AGGTTTTTGA AGAGGATGCT 
CTCAGCTGGG AAGATAAGCT GAACAGGATC ATGGCTCTCT TTGATGTGTG GATTGATGTG 
CAGAGGCGGT GGGTCTACCT GGAAGGTATC TTCACAGGCA GTGCAGATAT CAAGCACCTG 
CTGCCAGTGG AAACCCAGCG GTTTCAGAGC ATCAGCACTG AGTTTTTGGC TCTAATGAAA 
AAAGTGTCCA AGTCTCCCCT TGTTATGGAT GTTCTGAACA TCCAGGGAGT ACAGAGGTCT 
CTGGAAAGAT TGGCAGACCT GCTAGGAAAG ATCCAGAAAG CATTGGGAGA ATATCTGGAA 
AGAGAGCGGT CATCTTTCCC CAGGTTCTAT TTTGTGGGTG ATGAAGATTT GCTTGAAATC 
ATTGGAAACA GCAAGAATGT CGCTAAATTA CAGAAACACT TCAAGAAGAT GTTTGCTGGA 
GTTTCGAGCA TCATCCTGAA CGAGGATAAC TCTGTTGTTT TGGGTATTTC ATCTCGGGAA 
GGAGAGGAGG TTATGTTTAA AACTCCTGTG TCAATTACTG AACATCCCAA AATCAATGAG 
TGGCTCACAT TGGTAGAAAA GGAGATGAGA GTCACCCTGG CCAAACTGCT TGCTGAGTCT 
GTTACGGAAG TTGAGATTTT TGGTAAAGCA ACTTCAATTG ACCCAAATAC CTACATCACT 
TGGATTGATA AATACCAGGC CCAGCTTGTG GTTTTGTCAG CCCAGATAGC CTGGTCTGAG 
AACGTGGAGA CCGCACTGAG CAGCATGGGC GGAGGTGGAG ATGCCGCGCC CTTGCACTCT 
GTGCTGAGCA ATGTGGAGGT CACCCTCAAT GTGTTAGCAG ACTCTGTCCT CATGGAGCAG 
CCCCCACTCC GAAGGCGGAA GCTAGAACAC TTGATTACAG AGTTGGTTCA CCAGAGAGAT 
GTTACAAGGT CCTTGATCAA AAGCAAGATT GACAACGCCA AATCTTTTGA ATGGCTCAGC 
CAGATGCGAT TTTACTTTGA CCCTAAGCAA ACTGATGTGT TACAGCAGTT GTCAATTCAA 
ATGGCAAATG CCAAATTTAA CTATGGCTTT GAGTACCTGG GTGTTCAGGA CAAACTGGTC 
CAGACCCCCC TCACTGACCG CTGCTATTTG ACAATGACAC AAGCCTTGGA GGCCAGGCTG 
GGGGGTTCCC CATTTGGACC TGCTGGAACT GGGAAAACAG AGTCTGTCAA AGCTCTTGGC 
CATCAGCTTG GACGGTTTGT TTTAGTTTTC AACTGTGATG AAACCTTTGA TTTCCAGGCA 
ATGGGCCGGA TCTTTGTGGG CCTTTGCCAG GTGGGTGCCT GGGGCTGCTT TGACGAGTTC 
AACCGCCTGG AGGAGCGGAT GCTCTCGGCT GTGTCCCAGC AGGTGCAGTG CATACAGGAA 
GCACTGCGTG AACATTCCAA CCCCAACTAC GACAAGACCT CTGCCCCCAT TACTTGTGAG 
CTGCTGAACA AACAAGTCAA GGTGAGCCCG GACATGGCCA TCTTCATCAC CATGAACCCT 
GGCTACGCGG GCCGGTCTAA CCTTCCTGAC AACTTGAAGA AGCTGTTCCG GAGCTTGGCC 
ATGACCAAGC CCGACCGGCA GTTAATCGCC CAGGTCATGC TGTACTCACA GGGTTTCCGC 
ACTGCTGAAG TGCTTGCCAA CAAAATCGTC CCGTTTTTTA AACTATGCGA TGAGCAGCTC 
TCTTCCCAAA GCCATTATGA CTTCGGTCTT CGGGCTTTGA AGAGTGTGCT GGTGAGTGCA 
GGCAATGTGA AGAGAGAGAG AATCCAGAAG ATAAAGAGGG AGAAAGAGGA ACGAGGGGAA 
GCAGTTGATG AAGGAGAAAT TGCTGAAAAT CTCCCTGAAC AAGAGATTCT GATACAGAGC 
GTCTGTGAGA CGATGGTGCC AAAGCTGGTG GCAGAGGACA TCCCGCTGCT CTTCAGCCTC 
CTGTCGGACG TGTTCCCTGG AGTCCAGTAT CACAGGGGTG AGATGACTGC CCTTCGAGAG 
GAGCTGAAGA AAGTGTGTCA GGAGATGTAT TTGACATATG GAGATGGAGA AGAAGTTGGT 
GGAATGTGGG TTGAAAAGGT TCTCCAGCTC TATCAGATCA CCCAGATCAA TCATGGCCTG 
ATGATGGTGG GGCCCTCGGG AAGTGGGAAG AGCATGGCCT GGCGTGTCCT GCTGAAGGCA 
TTGGAGAGAC TCGAGGGTGT GGAAGGTGTG GCCCATATCA TCGACCCCAA GGCCATCAGC 
AAAGACCACC TCTACGGAAC CCTGGACCCC AACACCAGGG AATGGACAGA TGGGCTCTTC 
ACACACGTGC TGAGAAAGAT CATCGACAGC GTGAGAGGCG AGCTGCAGAA GCGCCAGTGG 
ATCGTCTTCG ATGGCGATGT GGATCCAGAG TGGGTTGAGA ACTTGAACTC AGTGCTGGAT 
GACAATAAGC TCCTAACTTT GCCCAATGGA GAGCGCCTCA GTCTTCCACC CAATGTGAGA 
ATAATGTTTG AGGTACAGGA CTTGAAATAC GCGACCTTGG CCACAGTGTC GCGCTGCGGC 
ATGGTCTGGT TCAGTGAGGA TGTGCTGAGC ACCGACATGA TCTTCAACAA CTTCCTGGCC 
AGGCTGCGCA GCATCCCGCT GGATGAAGGG GAGGATGAGG CACAGCGGCG GCGTAAGGGC 
AAAGAGGATG AGGGGGAGGA GGCCGCTTCC CCCATGCTGC AGATCCAAAG AGATGCAGCT 
ACGATCATGC AACCGTACTT CACGTCCAAC GGCCTGGTCA CCAAGGCGCT AGAGCACGCC 
TTCCAGCTGG AGCACATCAT GGACCTAACA CGCCTGCGCT GCCTGGGCTC GCTCTTCTCC 
ATGCTGCACC AGGCCTGCCG CAACGTGGCG CAGTATAACG CCAACCATCC CGACTTCCCC 
ATGCAGATCG AGCAGCTGGA GCGCTACATT CAGCGATATC TGGTTTATGC CATACTCTGG 
TCCCTGTCTG GAGACAGCCG GCTAAAAATG AGAGCAGAGC TGGGTGAATA CATCAGAAGA 
ATCACGACCG TGCCTCTGCC CACTGCGCCC AACATACCCA TTATCGATTA TGAGGTGTCC 
ATCAGCGGAG AATGGTCTCC GTGGCAGGCC AAGGTGCCTC AGATTGAAGT GGAGACGCAC 
AAGGTGGCAG CCCCTGATGT CGTCGTGCCA ACGCTGGACA CAGTCCGCCA CGAAGCCCTC 
TTGTACACTT GGCTGGCCGA ACACAAGCCC CTGGTCTTGT GTGGCCCTCC TGGGTCTGGC 
AAGACCATGA CACTCTTCAG CGCCCTCCGG GCCTTGCCTG ACATGGAGGT GGTGGGTCTC 
AACTTCTCCA GTGCTACTAC TCCAGAGCTG CTTCTGAAGA CTTTTGATCA CTACTGCGAG 
TACAGGCGCA CACCTAATGG GGTGGTTTTG GCTCCTGTTC AACTTGGAAA GTGGCTGGTG 
TTGTTCTGTG ATGAAATCAA CTTGCCAGAT ATGGATAAAT ATGGGACCCA GAGGGTCATA 
TCCTTCATCA GACAGATGGT GGAGCACGGA GGCTTTTACC GTACCTCAGA TCAAACATGG 
GTGAAGCTGG AGAGAATCCA GTTTGTTGGG GCTTGTAATC CCCCCACAGA CCCTGGAAGA 
AAGCCCCTCT CACACAGGTT CCTGCGCCAC GTGCCTGTCG TGTATGTGGA TTACCCGGGC 
CCCGCCTCCC TCACACAGAT CTACGGCACC TTCAACCGCG CCATGCTGAG GCTCATTCCA 
TCCCTGCGGA CGTATGCAGA GCCGCTCACT GCTGCCATGG TGGAGTTCTA CACCATGTCT 
CAGGAGAGAT TCACCCAGGA TACACAACCT CACTATATCT ATTCACCCCG TGAAATGACT 
AGGTGGGTGA GAGGCATCTT TGAAGCGCTG AGACCTCTGG AGACCCTGCC TGTTGAAGGC 
CTCATTCGGA TTTGGGCACA TGAAGCTCTG CGTCTCTTCC AAGATAGACT CGTAGAGGAT 
GAGGAGAGGC GTTGGACTGA TGAGAACATC GACACGGTTG CTCTGAAGCA CTTCCCTAAC 
ATCGACAGAG AGAAGGCAAT GAGCCGACCC ATCTTGTACA GCAACTGGCT GTCAAAGGAT 
TACATCCCAG TAGACCAAGA AGAGTTAAGA GATTATGTCA AAGCTAGGCT GAAGGTCTTT 
TATGAAGAAG AACTTGATGT TCCGCTGGTG CTGTTTAATG AAGTCCTAGA CCACGTGCTG 
AGGATTGACA GAATATTCCG TCAACCTCAA GGCCACTTGC TTCTGATTGG TGTTAGTGGA 
GCAGGAAAAA CTACCCTGTC TCGTTTCGTC GCCTGGATGA ACGGTTTGAG TGTGTACCAG 
ATTAAGGTCC ATAGGAAGTA CACAGGGGAA GACTTTGATG AAGATCTACG GACAGTGTTG 
AGACGTTCTG GCTGTAAAAA TGAAAAGATA GCATTTATAA TGGATGAATC TAATGTGTTA 
GATTCTGGAT TCCTGGAGCG AATGAATACC CTTCTGGCCA ATGGAGAGGT GCCTGGTCTC 
TTTGAAGGAG ACGAGTATGC CACCTTGATG ACGCAGTGCA AAGAGGGGGC ACAGAAGGAA 
GGCCTGATGC TGGACTCGCA CGAGGAGCTC TACAAGTGGT TCACTAGCCA GGTTATCCGC 
AACCTCCACG TCGTGTTCAC CATGAACCCG TCCTCGGAGG GACTCAAGGA CCGGGCAGCT 
ACATCACCAG CACTTTTCAA CAGGTGTGTG TTGAATTGGT TTGGAGACTG GTCCACCGAA 
GCACTGTATC AGGTTGGCAA AGAATTCACA AGTAAGATGG ATCTGGAGAA GCCAAATTAC 
ATCGTGCCTG ATTACATGCC AGTTGTGTAT GATAAGCTGC CGCAGCCACC ATCCCATCGG 
GAAGCCATTG TGAACAGCTG TGTGTTTGTT CATCAGACTC TTCACCAGGC GAATGCTCGG 
CTAGCAAAGC GAGGCGGCAG AACGATGGCC ATCACCCCTC GCCACTACCT GGACTTCATC 
AATCACTATG CCAACCTGTT CCACGAGAAG CGGAGCGAGC TGGAGGAGCA GCAGATGCAC 
TTGAACGTGG GGCTCAGGAA GATCAAAGAG ACAGTCGACC AGGTAGAAGA ACTGCGTCGT 
GACTTGAGGA TAAAGAGCCA AGAGCTGGAG GTGAAGAATG CAGCAGCCAA TGACAAGCTG 
AAAAAGATGG TGAAAGACCA GCAGGAGGCT GAAAAGAAGA AGGTTATGAG CCAAGAAATC 
CAGGAACAGC TGCATAAGCA GCAGGAGGTA ATTGCAGACA AACAGATGAG TGTCAAAGAA 
GATCTTGATA AGGTGGAACC TGCCGTCATT GAGGCCCAGA ATGCTGTGAA GTCGATCAAG 
AAGCAGCACC TGGTGGAGGT GAGGTCCATG GCCAACCCTC CTGCTGCTGT GAAGCTGGCG 
CTGGAGTCCA TCTGCCTGCT GCTGGGGGAA AGCACCACAG ACTGGAAGCA GATCCGCTCC 
ATCATCATGC GGGAGAACTT CATCCCCACC ATCGTCAACT TCTCTGCAGA GGAGATCAGT 
GACGCCATAA GGGAGAAGAT GAAGAAAAAT TACATGTCCA ATCCAAGTTA CAATTATGAA 
ATTGTGAATC GGGCTTCCCT GGCTTGCGGC CCTATGGTGA AATGGGCAAT TGCACAGCTT 
AACTATGCAG ACATGTTAAA GAGAGTGGAG CCCCTACGCA ATGAGCTGCA GAAGCTGGAA 
GATGACGCCA AGGACAACCA GCAGAAGGCC AACGAGGTGG AGCAGATGAT CCGAGACCTG 
GAAGCCAGCA TCGCCCGCTA CAAGGAGGAA TACGCCGTCC TGATCTCAGA GGCCCAGGCC 
ATCAAGGCAG ACCTGGCAGC TGTCGAGGCA AAAGTAAACC GGAGCACTGC TCTTCTGAAG 
AGCTTGTCTG CTGAACGTGA ACGATGGGAA AAAACAAGTG AAACTTTCAA AAACCAGATG 
TCCACCATTG CTGGGGACTG TCTCTTGTCA GCTGCGTTCA TTGCCTACGC GGGTTACTTT 
GACCAGCAGA TGCGTCAGAA CTTGTTCACT ACCTGGTCCC ATCACCTACA GCAAGCCAAC 
ATCCAGTTCC GTACAGATAT TGCCAGGACG GAATACCTTT CCAATGCTGA TGAGCGTCTT 
CGCTGGCAGG CCAGCTCCTT GCCTGCTGAT GACCTTTGCA CAGAAAATGC CATCATGCTG 
AAACGATTCA ATAGGTATCC GCTGATCATT GACCCCTCTG GACAGGCCAC AGAATTCATT 
ATGAATGAAT ATAAGGATCG TAAGATCACA CGGACCAGCT TCCTGGATGA CGCCTTCAGA 
AAGAACTTAG AGAGTGCACT GAGATTCGGT AACCCCCTTC TGGTCCAGGA TGTGGAAAGC 
TACGATCCAG TTTTGAACCC GGTGCTGAAC CGTGAAGTGC GGCGAACAGG GGGGAGAGTG 
CTGATCACTC TCGGGGACCA GGACATAGAC CTGTCGCCAT CGTTTGTCAT CTTCCTGTCC 
ACCCGGGATC CAACTGTCGA GTTCCCACCA GATCTCTGTT CCCGGGTTAC TTTTGTAAAC 
TTCACAGTTA CCCGTAGCAG TTTACAAAGC CAGTGTCTAA ATGAAGTACT TAAAGCAGAA 
AGACCTGATG TGGACGAGAA ACGATCTGAT CTTCTTAAAC TTCAAGGGGA ATTTCAGCTC 
CGTTTGCGTC AGCTGGAAAA ATCTCTACTA CAAGCTCTGA ACGAGGTGAA AGGGCGCATT 
TTGGATGACG ACACGATCAT AACCACTCTG GAGAACCTGA AGAGAGAGGC TGCAGAGGTC 
ACCAGGAAAG TTGAGGAGAC GGACATTGTC ATGCAGGAGG TGGAGACCGT GTCCCAGCAG 
TACCTCCCGC TCTCCACCGC CTGCAGCAGC ATCTACTTCA CCATGGAGTC CCTCAAGCAG 
ATACACTTCT TGTACCAGTA CTCCCTCCAG TTTTTCCTGG ACATTTATCA CAACGTCCTA 
TACGAGAACC CGAACCTGAA GGGTGTCACC GACCACACAC AGCGCCTGTC CATTATAACA 
AAGGACCTCT TCCAGGTGGC GTTTAACCGA GTGGCTCGAG GCATGCTGCA TCAGGACCAC 
ATTACCTTTG CCATGCTGCT GGCAAGAATC AAACTGAAGG GCACCGTGGG GGAGCCCACC 
TACGATGCAG AATTCCAGCA CTTCTTGAGA GGAAATGAGA TTGTCCTGAG TGCTGGCTCC 
ACCCCCAGGA TCCAGGGCCT GACTGTGGAG CAGGCGGAGG CGGTGGTGAG GCTGAGCTGC 
CTTCCCGCGT TTAAGGACTT GATTGCAAAG GTTCAGGCAG ACGAGCAATT TGGCATCTGG 
CTGGACAGCA GCTCCCCGGA GCAGACTGTG CCCTACCTCT GGAGTGAAGA AACACCTGCA 
ACACCCATTG GCCAGGCCAT CCACCGCCTG CTCCTGATCC AGGCTTTCCG GCCCGATCGC 
CTGTTGGCCA TGGCCCACAT GTTTGTTTCA ACAAACCTTG GGGAGTCTTT CATGTCCATC 
ATGGAGCAGC CGCTCGACCT GACCCACATT GTGGGCACAG AGGTGAAGCC CAACACTCCT 
GTCTTAATGT GCTCTGTGCC TGGTTATGAT GCCAGTGGAC ATGTCGAGGA CCTTGCAGCC 
GAGCAGAACA CGCAGATCAC TTCAATTGCA ATCGGCTCTG CAGAAGGCTT TAACCAAGCA 
GATAAGGCAA TAAACACCGC TGTAAAGTCG GGCAGGTGGG TGATGCTGAA GAATGTGCAT 
CTGGCCCCAG GGTGGCTGAT GCAGCTGGAG AAGAAGTTGC ATTCCCTGCA GCCGCATGCC 
TGCTTCCGAC TCTTCCTCAC CATGGAGATC AACCCCAAGG TGCCTGTGAA TCTGCTCCGT 
GCGGGCCGCA TCTTTGTGTT CGAGCCACCG CCAGGGGTGA AGGCCAACAT GCTGAGGACG 
TTCAGCAGCA TTCCCGTCTC ACGGATATGC AAGTCTCCCA ACGAGCGTGC CCGCTTGTAC 
TTCCTGCTGG CCTGGTTTCA TGCGATCATC CAAGAACGCT TACGATACGC ACCACTGGGG 
TGGTCAAAGA AGTATGAATT TGGAGAGTCT GACCTGCGGT CAGCTTGCGA TACGGTGGAC 
ACGTGGCTGG ATGACACGGC CAAGGGCAGG CAGAACATCT CACCGGATAA GATCCCGTGG 
TCTGCACTAA AGACCTTAAT GGCCCAGTCC ATTTATGGCG GGCGCGTGGA CAACGAGTTT 
GACCAGCGTC TGCTCAACAC CTTCCTGGAG CGCCTGTTCA CAACCAGGAG TTTCGACAGT 
GAGTTTAAGC TGGCATGCAA GGTCGACGGA CATAAAGACA TTCAAATGCC AGATGGCATC 
AGGCGAGAGG AGTTTGTGCA GTGGGTGGAG TTGCTCCCCG ACACCCAGAC GCCCTCCTGG 
CTGGGCCTGC CCAACAACGC CGAGAGAGTC CTCCTTACCA CACAGGGTGT GGACATGATC 
AGTAAAATGC TGAAGATGCA GATGTTGGAG GATGAGGACG ACCTGGCCTA CGCAGAGACT 
GAGAAGAAGA CGAGGACAGA CTCCACGTCC GACGGGCGCC CTGCCTGGAT GCGGACACTG 
CACACCACCG CGTCCAACTG GCTGCACCTC ATCCCCCAGA CGCTGAGCCA CCTCAAGCGC 
ACCGTGGAGA ATATCAAGGA TCCTTTGTTC AGGTTCTTTG AGAGAGAAGT GAAGATGGGC 
GCAAAGCTGC TTCAGGACGT TCGCCAGGAC CTTGCAGATG TCGTCCAGGT GTGCGAAGGA 
AAGAAGAAGC AGACCAACTA CTTGCGCACG CTGATCAACG AGCTAGTGAA AGGGATCTTG 
CCTCGGAGCT GGTCCCACTA CACGGTGCCT GCCGGCATGA CCGTCATCCA GTGGGTGTCC 
GACTTCAGCG AGAGGATCAA ACAGCTGCAG AACATCTCAC TGGCAGCTGC ATCTGGTGGC 
GCCAAGGAGC TAAAGAACAT CCACGTGTGC CTGGGTGGCC TGTTCGTGCC TGAGGCGTAC 
ATCACTGCCA CCAGGCAGTA TGTGGCCCAG GCCAACAGCT GGTCCCTGGA GGAGCTCTGC 
CTGGAAGTCA ACGTCACCAC CTCACAGGGC GCCACCCTTG ACGCTTGCAG CTTCGGAGTC 
ACGGGTTTGA AACTTCAAGG GGCCACGTGC AACAACAACA AGCTGTCACT GTCCAATGCC 
ATCTCAACCG CCCTTCCCCT GACGCAGCTG CGCTGGGTCA AGCAGACAAA CACCGAGAAG 
AAGGCCAGTG TGGTAACCTT ACCTGTCTAC CTGAACTTCA CCCGTGCAGA CCTCATCTTC 
ACCGTGGACT TCGAAATTGC TACAAAGGAG GATCCTCGCA GCTTCTACGA GCGGGGTGTC 
GCAGTCTTGT GCACAGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001367.2
CDS	165..14105
Translation	MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKSALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGVTGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAVLCTE

Target ORF information:

RefSeq Version	NM_001376.4
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein cytoplasmic 1 heavy chain 1 (DYNC1H1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001376.4

ORF Insert Sequence:

ATGTCGGAGC CCGGGGGCGG CGGCGGCGAG GACGGCTCGG CCGGATTGGA AGTGTCGGCC 
GTGCAGAATG TGGCGGACGT GTCGGTGCTG CAGAAGCACC TGCGCAAGCT GGTGCCGCTG 
CTGCTGGAGG ACGGCGGCGA GGCGCCGGCC GCGCTGGAGG CGGCGCTGGA GGAGAAGAGC 
GCCCTGGAGC AGATGCGCAA GTTCCTTTCG GACCCGCAGG TCCACACGGT GCTGGTGGAG 
CGCTCCACGC TCAAAGAGGA CGTCGGTGAT GAAGGAGAAG AAGAAAAAGA ATTCATTTCC 
TATAACATCA ACATAGACAT TCATTATGGG GTTAAATCCA ATAGCTTGGC ATTCATTAAA 
CGTACTCCCG TGATTGATGC AGATAAACCC GTGTCTTCTC AGCTCCGGGT CCTTACACTC 
AGTGAAGACT CGCCCTACGA AACTTTGCAT TCTTTCATTA GCAATGCAGT GGCTCCTTTT 
TTTAAGTCCT ACATTAGAGA GTCTGGCAAG GCAGACAGGG ATGGTGATAA AATGGCTCCT 
TCAGTTGAAA AGAAGATTGC AGAACTCGAA ATGGGACTCC TTCACTTGCA GCAAAATATT 
GAAATTCCGG AGATCAGCCT GCCGATTCAT CCAATGATCA CAAATGTTGC AAAACAGTGT 
TATGAGCGTG GAGAAAAGCC AAAAGTTACA GACTTTGGTG ATAAGGTTGA AGACCCAACA 
TTTCTTAATC AGTTACAATC TGGAGTTAAC CGCTGGATCC GAGAAATTCA AAAAGTGACC 
AAACTGGATC GAGATCCTGC ATCAGGAACT GCCTTACAGG AAATTAGTTT TTGGCTAAAC 
TTGGAACGTG CGTTATACCG CATCCAGGAG AAACGGGAGA GCCCGGAAGT TCTCCTGACT 
CTGGATATCT TGAAACATGG CAAGCGCTTC CATGCCACCG TCAGTTTTGA CACTGACACA 
GGTCTAAAAC AGGCTTTGGA AACTGTGAAT GACTACAATC CTCTGATGAA AGATTTCCCT 
CTGAATGATT TGCTGTCTGC CACGGAGCTG GACAAAATAA GACAGGCGCT TGTTGCCATT 
TTCACACATT TGAGAAAGAT CCGAAACACA AAATATCCTA TTCAGAGGGC ACTGCGTTTG 
GTGGAGGCAA TTTCAAGAGA CTTGAGTTCT CAATTACTCA AAGTATTGGG CACTAGGAAA 
TTGATGCATG TTGCTTATGA AGAATTTGAA AAAGTTATGG TAGCATGCTT TGAAGTTTTT 
CAGACTTGGG ATGATGAGTA TGAGAAACTT CAGGTATTGT TGAGAGACAT CGTCAAAAGA 
AAAAGGGAAG AAAATCTGAA GATGGTGTGG CGTATCAACC CTGCCCACAG GAAGCTGCAG 
GCCCGCCTTG ACCAGATGAG AAAATTTAGA CGCCAGCATG AACAGCTAAG AGCTGTTATC 
GTCAGGGTCC TGAGGCCACA GGTCACGGCA GTTGCACAAC AGAATCAAGG AGAGGTCCCT 
GAACCCCAAG ATATGAAAGT GGCTGAGGTT CTCTTTGATG CTGCAGATGC AAATGCCATT 
GAGGAAGTAA ACCTTGCTTA TGAGAACGTC AAGGAAGTGG ATGGACTGGA TGTTTCCAAA 
GAGGGCACGG AAGCCTGGGA GGCTGCTATG AAGAGGTACG ATGAGAGGAT CGACAGAGTG 
GAGACCCGGA TCACCGCTCG CCTTCGGGAT CAGCTTGGCA CAGCCAAGAA TGCCAACGAG 
ATGTTTAGGA TTTTCTCCAG GTTTAATGCA CTGTTTGTCA GGCCTCACAT CCGTGGGGCC 
ATTCGCGAAT ACCAGACCCA GCTGATCCAG CGCGTGAAAG ATGACATTGA GTCTCTTCAC 
GACAAGTTCA AGGTCCAGTA CCCACAGAGT CAGGCTTGTA AGATGAGTCA CGTTCGTGAC 
TTGCCCCCTG TGTCAGGGTC TATCATCTGG GCTAAACAGA TCGACAGGCA GCTGACGGCC 
TACATGAAGC GGGTGGAAGA TGTCCTTGGC AAGGGCTGGG AGAATCACGT GGAGGGGCAG 
AAGCTGAAGC AGGATGGAGA CAGCTTCCGC ATGAAGCTCA ACACGCAGGA GATCTTTGAT 
GACTGGGCAA GGAAGGTGCA GCAGCGCAAC CTCGGTGTCT CGGGGCGCAT TTTCACCATC 
GAAAGTACTC GGGTTCGGGG CCGAACTGGA AATGTGCTTA AGCTGAAAGT TAACTTTCTT 
CCTGAGATTA TCACACTATC CAAAGAAGTC CGGAACCTCA AATGGCTTGG TTTCCGCGTC 
CCACTGGCGA TTGTGAACAA AGCCCATCAA GCAAACCAGC TTTACCCGTT TGCCATCTCA 
CTGATCGAGA GCGTTCGTAC CTATGAACGG ACCTGCGAGA AGGTGGAGGA GCGGAACACC 
ATTTCCCTTT TGGTGGCTGG CTTGAAAAAG GAAGTGCAGG CCCTGATCGC AGAAGGCATT 
GCGTTGGTGT GGGAGTCCTA CAAACTTGAC CCATATGTAC AGCGCTTAGC AGAGACTGTC 
TTCAACTTCC AAGAAAAGGT GGATGATCTG CTGATCATTG AAGAAAAAAT AGACCTAGAA 
GTCCGTTCCT TGGAAACTTG TATGTATGAC CATAAGACAT TCTCGGAAAT CTTGAACAGA 
GTCCAGAAAG CAGTGGATGA CTTAAATCTG CACTCCTATT CCAATTTGCC CATCTGGGTC 
AACAAGCTTG ACATGGAGAT TGAAAGAATA TTGGGCGTCC GTCTGCAAGC TGGCCTGAGA 
GCTTGGACGC AGGTTCTTCT TGGACAAGCT GAAGATAAAG CAGAAGTTGA CATGGACACA 
GATGCTCCAC AAGTTAGTCA CAAGCCTGGT GGAGAGCCAA AGATCAAAAA TGTCGTTCAT 
GAGCTAAGAA TAACCAATCA GGTAATCTAC TTGAATCCAC CAATTGAAGA GTGCAGATAC 
AAGCTGTATC AGGAAATGTT TGCCTGGAAG ATGGTTGTAC TGTCTCTCCC CAGGATCCAG 
AGTCAGAGGT ACCAGGTGGG TGTACATTAC GAATTGACTG AGGAAGAGAA ATTCTATCGG 
AATGCTTTAA CACGGATGCC TGATGGCCCT GTTGCCCTGG AAGAGTCGTA TTCTGCTGTC 
ATGGGCATTG TATCTGAAGT TGAACAGTAT GTCAAGGTTT GGCTTCAGTA TCAGTGTTTA 
TGGGATATGC AAGCTGAAAA CATCTATAAC AGACTTGGAG AAGATCTCAA CAAATGGCAG 
GCTCTCCTGG TCCAAATAAG GAAGGCCAGA GGAACCTTTG ACAATGCAGA AACCAAGAAA 
GAGTTTGGAC CAGTAGTTAT AGATTATGGC AAGGTACAAT CTAAGGTGAA CTTGAAATAT 
GACTCTTGGC ATAAGGAGGT TCTTAGCAAA TTTGGGCAGA TGCTAGGATC AAACATGACG 
GAATTCCATT CCCAGATCTC AAAGTCCCGC CAAGAGTTGG AGCAGCACTC AGTAGACACG 
GCCAGCACCT CCGATGCAGT GACCTTCATC ACCTATGTGC AGTCTTTGAA ACGGAAGATC 
AAGCAGTTTG AGAAGCAAGT TGAGCTCTAC CGCAATGGCC AGCGCTTACT GGAAAAGCAA 
AGGTTCCAGT TCCCACCTTC CTGGCTTTAT ATTGACAACA TCGAGGGAGA GTGGGGAGCC 
TTCAATGACA TCATGCGGCG AAAGGACTCT GCCATTCAGC AGCAGGTGGC AAACCTGCAA 
ATGAAGATTG TCCAGGAGGA TCGGGCCGTG GAAAGCCGCA CCACCGACCT GCTGACTGAC 
TGGGAGAAGA CCAAGCCTGT CACGGGCAAC CTTCGCCCAG AAGAGGCACT TCAGGCTCTC 
ACCATATATG AGGGGAAGTT TGGTAGGCTG AAGGACGACA GAGAGAAGTG TGCAAAGGCC 
AAGGAGGCGC TGGAATTGAC AGATACTGGG CTTCTCAGTG GCAGTGAAGA GCGCGTGCAG 
GTGGCCTTAG AAGAATTACA GGACCTCAAA GGCGTTTGGT CAGAACTTTC TAAGGTTTGG 
GAGCAAATCG ATCAGATGAA GGAGCAACCC TGGGTTTCAG TACAGCCTCG AAAGCTTCGA 
CAAAATTTGG ATGCCCTCCT GAACCAGCTG AAAAGCTTCC CTGCCCGGTT GCGACAGTAT 
GCGTCCTATG AGTTTGTTCA GAGGCTTCTG AAAGGTTACA TGAAGATAAA TATGCTGGTG 
ATTGAACTGA AATCCGAAGC ACTTAAAGAC CGCCATTGGA AACAGCTCAT GAAAAGGCTT 
CACGTTAATT GGGTTGTTTC TGAGCTAACC CTTGGCCAAA TCTGGGATGT TGACTTGCAG 
AAAAATGAAG CGATTGTCAA GGATGTACTG CTTGTGGCAC AAGGGGAGAT GGCTTTGGAA 
GAATTTTTGA AGCAGATAAG AGAAGTGTGG AATACTTATG AACTAGACTT GGTTAATTAT 
CAGAACAAGT GCCGCTTGAT CCGTGGCTGG GATGACCTCT TCAACAAGGT CAAAGAACAC 
ATCAACAGCG TCTCGGCCAT GAAGCTCTCT CCGTATTACA AGGTTTTTGA AGAGGATGCT 
CTCAGCTGGG AAGATAAGCT GAACAGGATC ATGGCTCTCT TTGATGTGTG GATTGATGTG 
CAGAGGCGGT GGGTCTACCT GGAAGGTATC TTCACAGGCA GTGCAGATAT CAAGCACCTG 
CTGCCAGTGG AAACCCAGCG GTTTCAGAGC ATCAGCACTG AGTTTTTGGC TCTAATGAAA 
AAAGTGTCCA AGTCTCCCCT TGTTATGGAT GTTCTGAACA TCCAGGGAGT ACAGAGGTCT 
CTGGAAAGAT TGGCAGACCT GCTAGGAAAG ATCCAGAAAG CATTGGGAGA ATATCTGGAA 
AGAGAGCGGT CATCTTTCCC CAGGTTCTAT TTTGTGGGTG ATGAAGATTT GCTTGAAATC 
ATTGGAAACA GCAAGAATGT CGCTAAATTA CAGAAACACT TCAAGAAGAT GTTTGCTGGA 
GTTTCGAGCA TCATCCTGAA CGAGGATAAC TCTGTTGTTT TGGGTATTTC ATCTCGGGAA 
GGAGAGGAGG TTATGTTTAA AACTCCTGTG TCAATTACTG AACATCCCAA AATCAATGAG 
TGGCTCACAT TGGTAGAAAA GGAGATGAGA GTCACCCTGG CCAAACTGCT TGCTGAGTCT 
GTTACGGAAG TTGAGATTTT TGGTAAAGCA ACTTCAATTG ACCCAAATAC CTACATCACT 
TGGATTGATA AATACCAGGC CCAGCTTGTG GTTTTGTCAG CCCAGATAGC CTGGTCTGAG 
AACGTGGAGA CCGCACTGAG CAGCATGGGC GGAGGTGGAG ATGCCGCGCC CTTGCACTCT 
GTGCTGAGCA ATGTGGAGGT CACCCTCAAT GTGTTAGCAG ACTCTGTCCT CATGGAGCAG 
CCCCCACTCC GAAGGCGGAA GCTAGAACAC TTGATTACAG AGTTGGTTCA CCAGAGAGAT 
GTTACAAGGT CCTTGATCAA AAGCAAGATT GACAACGCCA AATCTTTTGA ATGGCTCAGC 
CAGATGCGAT TTTACTTTGA CCCTAAGCAA ACTGATGTGT TACAGCAGTT GTCAATTCAA 
ATGGCAAATG CCAAATTTAA CTATGGCTTT GAGTACCTGG GTGTTCAGGA CAAACTGGTC 
CAGACCCCCC TCACTGACCG CTGCTATTTG ACAATGACAC AAGCCTTGGA GGCCAGGCTG 
GGGGGTTCCC CATTTGGACC TGCTGGAACT GGGAAAACAG AGTCTGTCAA AGCTCTTGGC 
CATCAGCTTG GACGGTTTGT TTTAGTTTTC AACTGTGATG AAACCTTTGA TTTCCAGGCA 
ATGGGCCGGA TCTTTGTGGG CCTTTGCCAG GTGGGTGCCT GGGGCTGCTT TGACGAGTTC 
AACCGCCTGG AGGAGCGGAT GCTCTCGGCT GTGTCCCAGC AGGTGCAGTG CATACAGGAA 
GCACTGCGTG AACATTCCAA CCCCAACTAC GACAAGACCT CTGCCCCCAT TACTTGTGAG 
CTGCTGAACA AACAAGTCAA GGTGAGCCCG GACATGGCCA TCTTCATCAC CATGAACCCT 
GGCTACGCGG GCCGGTCTAA CCTTCCTGAC AACTTGAAGA AGCTGTTCCG GAGCTTGGCC 
ATGACCAAGC CCGACCGGCA GTTAATCGCC CAGGTCATGC TGTACTCACA GGGTTTCCGC 
ACTGCTGAAG TGCTTGCCAA CAAAATCGTC CCGTTTTTTA AACTATGCGA TGAGCAGCTC 
TCTTCCCAAA GCCATTATGA CTTCGGTCTT CGGGCTTTGA AGAGTGTGCT GGTGAGTGCA 
GGCAATGTGA AGAGAGAGAG AATCCAGAAG ATAAAGAGGG AGAAAGAGGA ACGAGGGGAA 
GCAGTTGATG AAGGAGAAAT TGCTGAAAAT CTCCCTGAAC AAGAGATTCT GATACAGAGC 
GTCTGTGAGA CGATGGTGCC AAAGCTGGTG GCAGAGGACA TCCCGCTGCT CTTCAGCCTC 
CTGTCGGACG TGTTCCCTGG AGTCCAGTAT CACAGGGGTG AGATGACTGC CCTTCGAGAG 
GAGCTGAAGA AAGTGTGTCA GGAGATGTAT TTGACATATG GAGATGGAGA AGAAGTTGGT 
GGAATGTGGG TTGAAAAGGT TCTCCAGCTC TATCAGATCA CCCAGATCAA TCATGGCCTG 
ATGATGGTGG GGCCCTCGGG AAGTGGGAAG AGCATGGCCT GGCGTGTCCT GCTGAAGGCA 
TTGGAGAGAC TCGAGGGTGT GGAAGGTGTG GCCCATATCA TCGACCCCAA GGCCATCAGC 
AAAGACCACC TCTACGGAAC CCTGGACCCC AACACCAGGG AATGGACAGA TGGGCTCTTC 
ACACACGTGC TGAGAAAGAT CATCGACAGC GTGAGAGGCG AGCTGCAGAA GCGCCAGTGG 
ATCGTCTTCG ATGGCGATGT GGATCCAGAG TGGGTTGAGA ACTTGAACTC AGTGCTGGAT 
GACAATAAGC TCCTAACTTT GCCCAATGGA GAGCGCCTCA GTCTTCCACC CAATGTGAGA 
ATAATGTTTG AGGTACAGGA CTTGAAATAC GCGACCTTGG CCACAGTGTC GCGCTGCGGC 
ATGGTCTGGT TCAGTGAGGA TGTGCTGAGC ACCGACATGA TCTTCAACAA CTTCCTGGCC 
AGGCTGCGCA GCATCCCGCT GGATGAAGGG GAGGATGAGG CACAGCGGCG GCGTAAGGGC 
AAAGAGGATG AGGGGGAGGA GGCCGCTTCC CCCATGCTGC AGATCCAAAG AGATGCAGCT 
ACGATCATGC AACCGTACTT CACGTCCAAC GGCCTGGTCA CCAAGGCGCT AGAGCACGCC 
TTCCAGCTGG AGCACATCAT GGACCTAACA CGCCTGCGCT GCCTGGGCTC GCTCTTCTCC 
ATGCTGCACC AGGCCTGCCG CAACGTGGCG CAGTATAACG CCAACCATCC CGACTTCCCC 
ATGCAGATCG AGCAGCTGGA GCGCTACATT CAGCGATATC TGGTTTATGC CATACTCTGG 
TCCCTGTCTG GAGACAGCCG GCTAAAAATG AGAGCAGAGC TGGGTGAATA CATCAGAAGA 
ATCACGACCG TGCCTCTGCC CACTGCGCCC AACATACCCA TTATCGATTA TGAGGTGTCC 
ATCAGCGGAG AATGGTCTCC GTGGCAGGCC AAGGTGCCTC AGATTGAAGT GGAGACGCAC 
AAGGTGGCAG CCCCTGATGT CGTCGTGCCA ACGCTGGACA CAGTCCGCCA CGAAGCCCTC 
TTGTACACTT GGCTGGCCGA ACACAAGCCC CTGGTCTTGT GTGGCCCTCC TGGGTCTGGC 
AAGACCATGA CACTCTTCAG CGCCCTCCGG GCCTTGCCTG ACATGGAGGT GGTGGGTCTC 
AACTTCTCCA GTGCTACTAC TCCAGAGCTG CTTCTGAAGA CTTTTGATCA CTACTGCGAG 
TACAGGCGCA CACCTAATGG GGTGGTTTTG GCTCCTGTTC AACTTGGAAA GTGGCTGGTG 
TTGTTCTGTG ATGAAATCAA CTTGCCAGAT ATGGATAAAT ATGGGACCCA GAGGGTCATA 
TCCTTCATCA GACAGATGGT GGAGCACGGA GGCTTTTACC GTACCTCAGA TCAAACATGG 
GTGAAGCTGG AGAGAATCCA GTTTGTTGGG GCTTGTAATC CCCCCACAGA CCCTGGAAGA 
AAGCCCCTCT CACACAGGTT CCTGCGCCAC GTGCCTGTCG TGTATGTGGA TTACCCGGGC 
CCCGCCTCCC TCACACAGAT CTACGGCACC TTCAACCGCG CCATGCTGAG GCTCATTCCA 
TCCCTGCGGA CGTATGCAGA GCCGCTCACT GCTGCCATGG TGGAGTTCTA CACCATGTCT 
CAGGAGAGAT TCACCCAGGA TACACAACCT CACTATATCT ATTCACCCCG TGAAATGACT 
AGGTGGGTGA GAGGCATCTT TGAAGCGCTG AGACCTCTGG AGACCCTGCC TGTTGAAGGC 
CTCATTCGGA TTTGGGCACA TGAAGCTCTG CGTCTCTTCC AAGATAGACT CGTAGAGGAT 
GAGGAGAGGC GTTGGACTGA TGAGAACATC GACACGGTTG CTCTGAAGCA CTTCCCTAAC 
ATCGACAGAG AGAAGGCAAT GAGCCGACCC ATCTTGTACA GCAACTGGCT GTCAAAGGAT 
TACATCCCAG TAGACCAAGA AGAGTTAAGA GATTATGTCA AAGCTAGGCT GAAGGTCTTT 
TATGAAGAAG AACTTGATGT TCCGCTGGTG CTGTTTAATG AAGTCCTAGA CCACGTGCTG 
AGGATTGACA GAATATTCCG TCAACCTCAA GGCCACTTGC TTCTGATTGG TGTTAGTGGA 
GCAGGAAAAA CTACCCTGTC TCGTTTCGTC GCCTGGATGA ACGGTTTGAG TGTGTACCAG 
ATTAAGGTCC ATAGGAAGTA CACAGGGGAA GACTTTGATG AAGATCTACG GACAGTGTTG 
AGACGTTCTG GCTGTAAAAA TGAAAAGATA GCATTTATAA TGGATGAATC TAATGTGTTA 
GATTCTGGAT TCCTGGAGCG AATGAATACC CTTCTGGCCA ATGGAGAGGT GCCTGGTCTC 
TTTGAAGGAG ACGAGTATGC CACCTTGATG ACGCAGTGCA AAGAGGGGGC ACAGAAGGAA 
GGCCTGATGC TGGACTCGCA CGAGGAGCTC TACAAGTGGT TCACTAGCCA GGTTATCCGC 
AACCTCCACG TCGTGTTCAC CATGAACCCG TCCTCGGAGG GACTCAAGGA CCGGGCAGCT 
ACATCACCAG CACTTTTCAA CAGGTGTGTG TTGAATTGGT TTGGAGACTG GTCCACCGAA 
GCACTGTATC AGGTTGGCAA AGAATTCACA AGTAAGATGG ATCTGGAGAA GCCAAATTAC 
ATCGTGCCTG ATTACATGCC AGTTGTGTAT GATAAGCTGC CGCAGCCACC ATCCCATCGG 
GAAGCCATTG TGAACAGCTG TGTGTTTGTT CATCAGACTC TTCACCAGGC GAATGCTCGG 
CTAGCAAAGC GAGGCGGCAG AACGATGGCC ATCACCCCTC GCCACTACCT GGACTTCATC 
AATCACTATG CCAACCTGTT CCACGAGAAG CGGAGCGAGC TGGAGGAGCA GCAGATGCAC 
TTGAACGTGG GGCTCAGGAA GATCAAAGAG ACAGTCGACC AGGTAGAAGA ACTGCGTCGT 
GACTTGAGGA TAAAGAGCCA AGAGCTGGAG GTGAAGAATG CAGCAGCCAA TGACAAGCTG 
AAAAAGATGG TGAAAGACCA GCAGGAGGCT GAAAAGAAGA AGGTTATGAG CCAAGAAATC 
CAGGAACAGC TGCATAAGCA GCAGGAGGTA ATTGCAGACA AACAGATGAG TGTCAAAGAA 
GATCTTGATA AGGTGGAACC TGCCGTCATT GAGGCCCAGA ATGCTGTGAA GTCGATCAAG 
AAGCAGCACC TGGTGGAGGT GAGGTCCATG GCCAACCCTC CTGCTGCTGT GAAGCTGGCG 
CTGGAGTCCA TCTGCCTGCT GCTGGGGGAA AGCACCACAG ACTGGAAGCA GATCCGCTCC 
ATCATCATGC GGGAGAACTT CATCCCCACC ATCGTCAACT TCTCTGCAGA GGAGATCAGT 
GACGCCATAA GGGAGAAGAT GAAGAAAAAT TACATGTCCA ATCCAAGTTA CAATTATGAA 
ATTGTGAATC GGGCTTCCCT GGCTTGCGGC CCTATGGTGA AATGGGCAAT TGCACAGCTT 
AACTATGCAG ACATGTTAAA GAGAGTGGAG CCCCTACGCA ATGAGCTGCA GAAGCTGGAA 
GATGACGCCA AGGACAACCA GCAGAAGGCC AACGAGGTGG AGCAGATGAT CCGAGACCTG 
GAAGCCAGCA TCGCCCGCTA CAAGGAGGAA TACGCCGTCC TGATCTCAGA GGCCCAGGCC 
ATCAAGGCAG ACCTGGCAGC TGTCGAGGCA AAAGTAAACC GGAGCACTGC TCTTCTGAAG 
AGCTTGTCTG CTGAACGTGA ACGATGGGAA AAAACAAGTG AAACTTTCAA AAACCAGATG 
TCCACCATTG CTGGGGACTG TCTCTTGTCA GCTGCGTTCA TTGCCTACGC GGGTTACTTT 
GACCAGCAGA TGCGTCAGAA CTTGTTCACT ACCTGGTCCC ATCACCTACA GCAAGCCAAC 
ATCCAGTTCC GTACAGATAT TGCCAGGACG GAATACCTTT CCAATGCTGA TGAGCGTCTT 
CGCTGGCAGG CCAGCTCCTT GCCTGCTGAT GACCTTTGCA CAGAAAATGC CATCATGCTG 
AAACGATTCA ATAGGTATCC GCTGATCATT GACCCCTCTG GACAGGCCAC AGAATTCATT 
ATGAATGAAT ATAAGGATCG TAAGATCACA CGGACCAGCT TCCTGGATGA CGCCTTCAGA 
AAGAACTTAG AGAGTGCACT GAGATTCGGT AACCCCCTTC TGGTCCAGGA TGTGGAAAGC 
TACGATCCAG TTTTGAACCC GGTGCTGAAC CGTGAAGTGC GGCGAACAGG GGGGAGAGTG 
CTGATCACTC TCGGGGACCA GGACATAGAC CTGTCGCCAT CGTTTGTCAT CTTCCTGTCC 
ACCCGGGATC CAACTGTCGA GTTCCCACCA GATCTCTGTT CCCGGGTTAC TTTTGTAAAC 
TTCACAGTTA CCCGTAGCAG TTTACAAAGC CAGTGTCTAA ATGAAGTACT TAAAGCAGAA 
AGACCTGATG TGGACGAGAA ACGATCTGAT CTTCTTAAAC TTCAAGGGGA ATTTCAGCTC 
CGTTTGCGTC AGCTGGAAAA ATCTCTACTA CAAGCTCTGA ACGAGGTGAA AGGGCGCATT 
TTGGATGACG ACACGATCAT AACCACTCTG GAGAACCTGA AGAGAGAGGC TGCAGAGGTC 
ACCAGGAAAG TTGAGGAGAC GGACATTGTC ATGCAGGAGG TGGAGACCGT GTCCCAGCAG 
TACCTCCCGC TCTCCACCGC CTGCAGCAGC ATCTACTTCA CCATGGAGTC CCTCAAGCAG 
ATACACTTCT TGTACCAGTA CTCCCTCCAG TTTTTCCTGG ACATTTATCA CAACGTCCTA 
TACGAGAACC CGAACCTGAA GGGTGTCACC GACCACACAC AGCGCCTGTC CATTATAACA 
AAGGACCTCT TCCAGGTGGC GTTTAACCGA GTGGCTCGAG GCATGCTGCA TCAGGACCAC 
ATTACCTTTG CCATGCTGCT GGCAAGAATC AAACTGAAGG GCACCGTGGG GGAGCCCACC 
TACGATGCAG AATTCCAGCA CTTCTTGAGA GGAAATGAGA TTGTCCTGAG TGCTGGCTCC 
ACCCCCAGGA TCCAGGGCCT GACTGTGGAG CAGGCGGAGG CGGTGGTGAG GCTGAGCTGC 
CTTCCCGCGT TTAAGGACTT GATTGCAAAG GTTCAGGCAG ACGAGCAATT TGGCATCTGG 
CTGGACAGCA GCTCCCCGGA GCAGACTGTG CCCTACCTCT GGAGTGAAGA AACACCTGCA 
ACACCCATTG GCCAGGCCAT CCACCGCCTG CTCCTGATCC AGGCTTTCCG GCCCGATCGC 
CTGTTGGCCA TGGCCCACAT GTTTGTTTCA ACAAACCTTG GGGAGTCTTT CATGTCCATC 
ATGGAGCAGC CGCTCGACCT GACCCACATT GTGGGCACAG AGGTGAAGCC CAACACTCCT 
GTCTTAATGT GCTCTGTGCC TGGTTATGAT GCCAGTGGAC ATGTCGAGGA CCTTGCAGCC 
GAGCAGAACA CGCAGATCAC TTCAATTGCA ATCGGCTCTG CAGAAGGCTT TAACCAAGCA 
GATAAGGCAA TAAACACCGC TGTAAAGTCG GGCAGGTGGG TGATGCTGAA GAATGTGCAT 
CTGGCCCCAG GGTGGCTGAT GCAGCTGGAG AAGAAGTTGC ATTCCCTGCA GCCGCATGCC 
TGCTTCCGAC TCTTCCTCAC CATGGAGATC AACCCCAAGG TGCCTGTGAA TCTGCTCCGT 
GCGGGCCGCA TCTTTGTGTT CGAGCCACCG CCAGGGGTGA AGGCCAACAT GCTGAGGACG 
TTCAGCAGCA TTCCCGTCTC ACGGATATGC AAGTCTCCCA ACGAGCGTGC CCGCTTGTAC 
TTCCTGCTGG CCTGGTTTCA TGCGATCATC CAAGAACGCT TACGATACGC ACCACTGGGG 
TGGTCAAAGA AGTATGAATT TGGAGAGTCT GACCTGCGGT CAGCTTGCGA TACGGTGGAC 
ACGTGGCTGG ATGACACGGC CAAGGGCAGG CAGAACATCT CACCGGATAA GATCCCGTGG 
TCTGCACTAA AGACCTTAAT GGCCCAGTCC ATTTATGGCG GGCGCGTGGA CAACGAGTTT 
GACCAGCGTC TGCTCAACAC CTTCCTGGAG CGCCTGTTCA CAACCAGGAG TTTCGACAGT 
GAGTTTAAGC TGGCATGCAA GGTCGACGGA CATAAAGACA TTCAAATGCC AGATGGCATC 
AGGCGAGAGG AGTTTGTGCA GTGGGTGGAG TTGCTCCCCG ACACCCAGAC GCCCTCCTGG 
CTGGGCCTGC CCAACAACGC CGAGAGAGTC CTCCTTACCA CACAGGGTGT GGACATGATC 
AGTAAAATGC TGAAGATGCA GATGTTGGAG GATGAGGACG ACCTGGCCTA CGCAGAGACT 
GAGAAGAAGA CGAGGACAGA CTCCACGTCC GACGGGCGCC CTGCCTGGAT GCGGACACTG 
CACACCACCG CGTCCAACTG GCTGCACCTC ATCCCCCAGA CGCTGAGCCA CCTCAAGCGC 
ACCGTGGAGA ATATCAAGGA TCCTTTGTTC AGGTTCTTTG AGAGAGAAGT GAAGATGGGC 
GCAAAGCTGC TTCAGGACGT TCGCCAGGAC CTTGCAGATG TCGTCCAGGT GTGCGAAGGA 
AAGAAGAAGC AGACCAACTA CTTGCGCACG CTGATCAACG AGCTAGTGAA AGGGATCTTG 
CCTCGGAGCT GGTCCCACTA CACGGTGCCT GCCGGCATGA CCGTCATCCA GTGGGTGTCC 
GACTTCAGCG AGAGGATCAA ACAGCTGCAG AACATCTCAC TGGCAGCTGC ATCTGGTGGC 
GCCAAGGAGC TAAAGAACAT CCACGTGTGC CTGGGTGGCC TGTTCGTGCC TGAGGCGTAC 
ATCACTGCCA CCAGGCAGTA TGTGGCCCAG GCCAACAGCT GGTCCCTGGA GGAGCTCTGC 
CTGGAAGTCA ACGTCACCAC CTCACAGGGC GCCACCCTTG ACGCTTGCAG CTTCGGAGTC 
ACGGGTTTGA AACTTCAAGG GGCCACGTGC AACAACAACA AGCTGTCACT GTCCAATGCC 
ATCTCAACCG CCCTTCCCCT GACGCAGCTG CGCTGGGTCA AGCAGACAAA CACCGAGAAG 
AAGGCCAGTG TGGTAACCTT ACCTGTCTAC CTGAACTTCA CCCGTGCAGA CCTCATCTTC 
ACCGTGGACT TCGAAATTGC TACAAAGGAG GATCCTCGCA GCTTCTACGA GCGGGGTGTC 
GCAGTCTTGT GCACAGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A missense mutation in DYNC1H1 gene causing spinal muscular atrophy - Lower extremity, dominant.
Neurologia i neurochirurgia polska(2017 Dec)
Das J,Lilleker JB,Jabbal K,Ealing J

NuMA recruits dynein activity to microtubule minus-ends at mitosis.
eLife6(2017 Nov)
Hueschen CL,Kenny SJ,Xu K,Dumont S

Expanding the phenotypic spectrum associated with mutations of DYNC1H1.
Neuromuscular disorders : NMD27(7)607-615(2017 Jul)
Beecroft SJ,McLean CA,Delatycki MB,Koshy K,Yiu E,Haliloglu G,Orhan D,Lamont PJ,Davis MR,Laing NG,Ravenscroft G

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle.
The Journal of biological chemistry291(38)20055-67(2016 09)
Chu X,Chen X,Wan Q,Zheng Z,Du Q

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DYNC1H1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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