Gene Symbol | RAT1 |
Entrez Gene ID | 854213 |
Full Name | ssRNA exonuclease RAT1 |
Synonyms | HKE1,TAP1,XRN2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RAT1 cDNA ORF clone
Gene Symbol | RAT1 |
Entrez Gene ID | 854213 |
Full Name | ssRNA exonuclease RAT1 |
Synonyms | HKE1,TAP1,XRN2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183467.1 | NP_014691.1 | ssRNA exonuclease RAT1 |
Eremothecium gossypii | AGOS_AGR303W | NP_986969.2 |
Pan troglodytes (chimpanzee) | XRN2 | XP_514546.2 |
Canis lupus familiaris (dog) | XRN2 | XP_534324.2 |
Rattus norvegicus (Norway rat) | Xrn2 | NP_001102066.1 |
Drosophila melanogaster (fruit fly) | Rat1 | NP_001260166.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004090 | XP_309641.5 |
Caenorhabditis elegans (roundworm) | xrn-2 | NP_496958.2 |
Saccharomyces cerevisiae (baker's yeast) | RAT1 | NP_014691.1 |
Xenopus tropicalis (tropical clawed frog) | xrn2 | XP_002939479.1 |
Homo sapiens (human) | XRN2 | NP_036387.2 |
Bos taurus (cattle) | XRN2 | NP_001179401.1 |
Mus musculus (house mouse) | Xrn2 | NP_036047.2 |
Schizosaccharomyces pombe (fission yeast) | dhp1 | NP_594155.1 |
Neurospora crassa | NCU01643 | XP_956265.1 |
XRN2 | XP_001094734.2 | |
Gallus gallus (chicken) | XRN2 | NP_001026204.1 |
Danio rerio (zebrafish) | xrn2 | NP_001001944.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_11426 | XP_003717803.1 |
Kluyveromyces lactis | KLLA0F07469g | XP_455419.1 |
Arabidopsis thaliana (thale cress) | XRN3 | NP_565114.1 |
Oryza sativa (rice) | Os01g0872700 | NP_001044947.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Results indicate that multiple mechanistic features contribute to 5'-3' exoribonuclease Rat1-mediated termination of RNA polymerase II (RNAPII).
Title: Unraveling the mechanistic features of RNA polymerase II termination by the 5'-3' exoribonuclease Rat1.
Data indicate that Rat1 exonuclease (Rat1) acts catalytically in 5.8S and 25S rRNA processing but binds to the pre-rRNA prior to these activities.
Title: Kinetic analysis demonstrates a requirement for the Rat1 exonuclease in cotranscriptional pre-rRNA cleavage.
Degradation of the nascent transcript allows Rat1 to pursue Pol II in a guided fashion and arrive at the site of RNA exit from Pol II.
Title: Dismantling promoter-driven RNA polymerase II transcription complexes in vitro by the termination factor Rat1.
Rat1 exonuclease pre-rRNA folding and 5.8S rRNA maturation are regulated by a cluster of ribosome synthesis factors
Title: A cluster of ribosome synthesis factors regulate pre-rRNA folding and 5.8S rRNA maturation by the Rat1 exonuclease.
data suggest that Rat1p serves to terminate RNAPII molecules engaged in the production of uncapped RNA, regardless of their position on the gene locus.
Title: The yeast 5'-3' exonuclease Rat1p functions during transcription elongation by RNA polymerase II.
The following RAT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03359 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183467.1 | |
Accession Version | NM_001183467.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3021bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | ssRNA exonuclease RAT1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGGTGTTC CGTCATTTTT CAGATGGCTA TCTCGAAAAT ATCCAAAGAT CATATCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014691.1 |
CDS | 1..3021 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183467.1 |
1 | ATGGGTGTTC CGTCATTTTT CAGATGGCTA TCTCGAAAAT ATCCAAAGAT CATATCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |