Gene Symbol | RAD6 |
Entrez Gene ID | 852822 |
Full Name | E2 ubiquitin-conjugating protein RAD6 |
Synonyms | PSO8,UBC2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RAD6 cDNA ORF clone
Gene Symbol | RAD6 |
Entrez Gene ID | 852822 |
Full Name | E2 ubiquitin-conjugating protein RAD6 |
Synonyms | PSO8,UBC2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180923.1 | NP_011457.1 | E2 ubiquitin-conjugating protein RAD6 |
Pan troglodytes (chimpanzee) | UBE2B | XP_517935.2 |
Bos taurus (cattle) | UBE2B | NP_001032536.1 |
Rattus norvegicus (Norway rat) | Ube2b | NP_112400.1 |
Neurospora crassa | NCU09731 | XP_964433.2 |
UBE2B | XP_001109004.1 | |
Danio rerio (zebrafish) | ube2b | NP_001002747.1 |
Saccharomyces cerevisiae (baker's yeast) | RAD6 | NP_011457.1 |
Kluyveromyces lactis | KLLA0C05632g | XP_452450.1 |
Homo sapiens (human) | UBE2B | NP_003328.1 |
Mus musculus (house mouse) | Ube2b | NP_033484.3 |
Xenopus tropicalis (tropical clawed frog) | ube2b | NP_001005124.1 |
Canis lupus familiaris (dog) | UBE2B | XP_850657.1 |
Gallus gallus (chicken) | LOC100857678 | XP_004945057.1 |
Schizosaccharomyces pombe (fission yeast) | rhp6 | NP_592876.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01756 | XP_003714754.1 |
Eremothecium gossypii | AGOS_AAR156C | NP_982699.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rad6-Bre1 pathway regulates both telomere length and recombination through its role in histone H2B lysine 123 mono-ubiquitination
Title: Rad6-Bre1-mediated H2B ubiquitination regulates telomere replication by promoting telomere-end resection.
The histone modification domain of Paf1 complex subunit Rtf1 directly stimulates H2B ubiquitylation through an interaction with Rad6.
Title: The Histone Modification Domain of Paf1 Complex Subunit Rtf1 Directly Stimulates H2B Ubiquitylation through an Interaction with Rad6.
Free ubiquitin interacts weakly with both non-canonical and canonical backside residues of Rad6 and that mutations of non-canonical residues have deleterious effects on Rad6 activity.
Title: Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity.
The authors demonstrate that tombusvirus RNA replication and the mono- and bi-ubiquitination level of p33 is decreased in rad6Delta yeast. However, plasmid-based expression of the Arabidopsis Ubc2p could complement both defects in rad6Delta yeast.
Title: Cellular Ubc2/Rad6 E2 ubiquitin-conjugating enzyme facilitates tombusvirus replication in yeast and plants.
The major ubiquitin ligase targeting the superfluous Fas2 subunit to the proteasome is Ubr1. The ubiquitin-conjugating enzymes Ubc2 and Ubc4 assist the degradation process.
Title: Quality control of a cytoplasmic protein complex: chaperone motors and the ubiquitin-proteasome system govern the fate of orphan fatty acid synthase subunit Fas2 of yeast.
The following RAD6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAD6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02183 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180923.1 | |
Accession Version | NM_001180923.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 519bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | E2 ubiquitin-conjugating protein RAD6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCCACAC CAGCTAGAAG AAGGTTGATG AGAGATTTTA AACGTATGAA GGAAGATGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011457.1 |
CDS | 1..519 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180923.1 |
1 | ATGTCCACAC CAGCTAGAAG AAGGTTGATG AGAGATTTTA AACGTATGAA GGAAGATGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |