Gene Symbol | NDT80 |
Entrez Gene ID | 856524 |
Full Name | transcription factor NDT80 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » NDT80 cDNA ORF clone
Gene Symbol | NDT80 |
Entrez Gene ID | 856524 |
Full Name | transcription factor NDT80 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179254.1 | NP_011992.1 | transcription factor NDT80 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
Johnston M, Andrews S, Brinkman R, Cooper J, Ding H, Dover J, Du Z, Favello A, Fulton L, Gattung S
Science (New York, N.Y.)265(5181)2077-82(1994 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ndt80 transcription of CDC5 results in degradation of Red1, a meiosis-specific protein required for Mek1 activation, thereby abolishing Mek1 activity completely. Elimination of Mek1 kinase activity allows Rad51-mediated repair of any remaining DSBs. In this way, cells do not enter Meiosis I until recombination is complete and all DSBs are repair
Title: Coordination of Double Strand Break Repair and Meiotic Progression in Yeast by a Mek1-Ndt80 Negative Feedback Loop.
The findings suggest that irreversibility of meiotic commitment is a consequence of the NDT80 transcriptional positive feedback loop, which provides the high-level of Ndt80 required for the developmental switch of meiotic commitment.
Title: Positive feedback of NDT80 expression ensures irreversible meiotic commitment in budding yeast.
Our results reveal a role for Cdc5 in meiotic checkpoint control by regulating Ndt80 function
Title: The budding yeast polo-like kinase Cdc5 regulates the Ndt80 branch of the meiotic recombination checkpoint pathway.
nuclear localization of Ndt80 is regulated by the pachytene checkpoint through a cytoplasmic anchor mechanism
Title: Nuclear localization of the meiosis-specific transcription factor Ndt80 is regulated by the pachytene checkpoint.
transient induction of a transcription factor (NDT80) essential for later stages of gametogenesis extends the replicative life span of aged cells
Title: Gametogenesis eliminates age-induced cellular damage and resets life span in yeast.
The following NDT80 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NDT80 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05322 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179254.1 | |
Accession Version | NM_001179254.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1884bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | transcription factor NDT80 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001140). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Veresion :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAATGAAA TGGAAAACAC AGATCCAGTA TTACAGGATG ATCTCGTATC CAAATATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011992.1 |
CDS | 1..1884 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179254.1 |
1 | ATGAATGAAA TGGAAAACAC AGATCCAGTA TTACAGGATG ATCTCGTATC CAAATATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII. |