Gene Symbol | HRQ1 |
Entrez Gene ID | 851885 |
Full Name | ATP-dependent 3'-5' DNA helicase |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » HRQ1 cDNA ORF clone
Gene Symbol | HRQ1 |
Entrez Gene ID | 851885 |
Full Name | ATP-dependent 3'-5' DNA helicase |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180599.3 | NP_010577.3 | ATP-dependent 3'-5' DNA helicase |
Arabidopsis thaliana (thale cress) | AT5G08110 | NP_196428.2 |
Oryza sativa (rice) | Os02g0111900 | NP_001045657.1 |
Saccharomyces cerevisiae (baker's yeast) | HRQ1 | NP_010577.3 |
Eremothecium gossypii | AGOS_AAL080W | NP_982462.1 |
Schizosaccharomyces pombe (fission yeast) | SPAC23A1.19c | NP_594448.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_13223 | XP_003711922.1 |
Neurospora crassa | NCU06365 | XP_962399.1 |
Kluyveromyces lactis | KLLA0C10736g | XP_452678.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results establish the importance of DNA sequence in Hrq1 helicase activity, and the absence of Hrq1 strand annealing activity explains the previously identified discrepancies between S. cerevisiae Hrq1 and human RecQ4.
Title: Saccharomyces cerevisiae Hrq1 helicase activity is affected by the sequence but not the length of single-stranded DNA.
Overexpression of Hrq1K318A helicase-deficient protein rendered mutant cells more sensitive to 4-nitroquinoline-1-oxide and cisplatin, suggesting that helicase activity is required for the proper function of Hrq1 in nucleotide excision repair.
Title: Hrq1 facilitates nucleotide excision repair of DNA damage induced by 4-nitroquinoline-1-oxide and cisplatin in Saccharomyces cerevisiae.
Hrq1 acts catalytically to protect against DNA interstrand crosslinks and affects telomere length by a noncatalytic mechanism.
Title: Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity.
These results suggest that Hrq1 is involved in recombination and DNA repair pathways in Saccharomyces cerevisiae independent of Sgs1.
Title: Hrq1 functions independently of Sgs1 to preserve genome integrity in Saccharomyces cerevisiae.
these results indicate that Hrq1 has vigorous helicase activity that deserves further characterization to expand our understanding of RecQ helicases.
Title: Saccharomyces cerevisiae Hrq1 requires a long 3'-tailed DNA substrate for helicase activity.
The following HRQ1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HRQ1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01368 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180599.3 | |
Accession Version | NM_001180599.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3234bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | ATP-dependent 3'-5' DNA helicase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). On Jul 30, 2012 this sequence version replaced NM_001180599.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAGGAAG GACCTATCAA AAAGAAACTG AAGTCAGCAG GTCAAGGGAG TGGAAAGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010577.3 |
CDS | 1..3234 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180599.3 |
1 | ATGGAGGAAG GACCTATCAA AAAGAAACTG AAGTCAGCAG GTCAAGGGAG TGGAAAGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |