Psmd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Psmd1
Entrez Gene ID	83806
Full Name	proteasome 26S subunit, non-ATPase 1
General protein information	Preferred Names proteasome 26S subunit, non-ATPase 1 Names 26S proteasome non-ATPase regulatory subunit 1 26S proteasome p112 subunit 26S proteasome regulatory subunit RPN2 26S proteasome regulatory subunit S1 26S proteasome, subunit p112 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q35
Summary	is upregulated by glutamate excitotoxicity and may be involved in neurodegenerative processes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031978.1	NP_114184.1	26S proteasome non-ATPase regulatory subunit 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PSMD1	NP_001233478.1
Canis lupus familiaris (dog)	PSMD1	XP_003433398.1
Rattus norvegicus (Norway rat)	Psmd1	NP_114184.1
Saccharomyces cerevisiae (baker's yeast)	RPN2	NP_012190.1
	PSMD1	XP_001113035.1
Danio rerio (zebrafish)	psmd1	NP_957478.1
Drosophila melanogaster (fruit fly)	Rpn2	NP_001263057.1
Neurospora crassa	NCU09450	XP_958036.1
Arabidopsis thaliana (thale cress)	AT2G32730	NP_180832.1
Xenopus tropicalis (tropical clawed frog)	psmd1	NP_998867.1
Homo sapiens (human)	PSMD1	NP_002798.2
Mus musculus (house mouse)	Psmd1	NP_081633.1
Kluyveromyces lactis	KLLA0C09284g	XP_452613.1
Eremothecium gossypii	AGOS_ACL033C	NP_983371.1
Schizosaccharomyces pombe (fission yeast)	rpn2	NP_596381.1
Gallus gallus (chicken)	PSMD1	NP_001012618.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001745	XP_321340.5
Oryza sativa (rice)	Os08g0224700	NP_001061278.1
Bos taurus (cattle)	PSMD1	NP_001094547.1
Magnaporthe oryzae (rice blast fungus)	MGG_05991	XP_003711836.1
Arabidopsis thaliana (thale cress)	AT1G04810	NP_171973.1

Gene Ontology
Bibliography

Related articles in PubMed

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Protein aggregation and proteasome dysfunction after brain ischemia.
Ge P, Luo Y, Liu CL, Hu B
Stroke38(12)3230-6(2007 Dec)

The cyclophilin-like domain of Ran-binding protein-2 modulates selectively the activity of the ubiquitin-proteasome system and protein biogenesis.
Yi H, Friedman JL, Ferreira PA
The Journal of biological chemistry282(48)34770-8(2007 Nov)

Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.
Wang X, Chen CF, Baker PR, Chen PL, Kaiser P, Huang L
Biochemistry46(11)3553-65(2007 Mar)

An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity.
Stanhill A, Haynes CM, Zhang Y, Min G, Steele MC, Kalinina J, Martinez E, Pickart CM, Kong XP, Ron D
Molecular cell23(6)875-85(2006 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

analysis of proteasome 19 and 26 dysfunction after brain ischemia
Title: Protein aggregation and proteasome dysfunction after brain ischemia.

Proteasome inhibition exerts an acute pro-survival action by stabilizing transcription factors.
Title: Proteasome inhibition elicits a biphasic effect on neuronal apoptosis via differential regulation of pro-survival and pro-apoptotic transcription factors.

The following Psmd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Psmd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08896	NM_031978.1 Latest version!	Rattus norvegicus proteasome 26S subunit, non-ATPase 1 (Psmd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Psmd1 ( NM_031978.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_114184.1 Rattus norvegicus proteasome 26S subunit, non-ATPase 1 (Psmd1), mRNA.

Price & Availability↑

CloneID	ORa08896
Clone ID Related Accession (Same CDS sequence)	NM_031978.1
Accession Version	NM_031978.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2862bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	26S proteasome non-ATPase regulatory subunit 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ006340.1. ##Evidence-Data-START## Transcript exon combination :: AJ006340.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGATCACTT CAGCCGCTGG AATTATTTCT CTTCTGGATG AAGAAGAGCC ACAGCTCAAG 
GAATTTGCAC TACACAAATT GAATGCAGTT GTGAATGACT TCTGGGCAGA AATTTCTGAG 
TCTGTAGACA AAATAGAAGT TTTATATGAA GATGAAGGTT TCCGCAGTCG GCAGTTTGCA 
GCCTTGGTGG CATCGAAAGT ATTTTATCAC CTGGGGGCTT TCGAGGAGTC TCTGAATTAT 
GCTCTTGGAG CAGGTGACCT CTTCAATGTC AATGATAACT CTGAATATGT GGAGACTATT 
ATAGCAAAAT GCATTGATCA TTATACCAAA CAGTGTGTGG AAAATGCAGA TTTGCCTGAA 
GGAGAAAAGA AGCCAATTGA CCAGAGATTG GAAGGCATCG TGAATAAGAT GTTCCAGCGA 
TGTCTCGATG ATCACAAGTA TAAGCAAGCG ATTGGCATTG CTCTGGAGAC CAGGAGACTA 
GATGTGTTTG AGAAGACTAT ACTGGAATCT AATGATGTCC CAGGAATGCT AGCTTACAGC 
CTCAAGCTCT GCATGTCTTT AATGCAGAAT AAGCAGTTTC GGAATAAAGT ATTGCGAGTC 
CTGGTTAAAA TCTACATGAA CTTGGAAAAA CCTGATTTCA TCAATGTTTG TCAGTGCTTA 
ATCTTCTTAG ATGACACCCA GGCCGTGAGT GATATCTTAG AAAAGCTGGT AAAGGAAGAC 
AACCTGCTGA TGGCCTATCA GATTTGCTTT GATTTGTACG AAAGTGCCAG CCAGCAGTTT 
TTGTCATCTG TGATCCAGAA TCTTCGAACT GTTGGGACCC CTATTGCTTC TGTGCCTGGA 
TCTACCAATA CGGGTACTGT GCCAGGACCA GAGAAAGACA GTGACTCTAT GGAGACCGAG 
GAGAAGACAG CCGGTGCAGT GGCAGGGAAA ACACCAGACG CTAGTCCAGA GCCCAAGGAC 
CAGACATTGA AAATGATTAA AATTTTAAGT GGTGAAATGG CTATCGAGTT ACACCTGCAG 
TTCCTAATAC GCAATAATAA CACAGACCTC ATGATTCTGA AAAACACAAA GGATGCAGTA 
CGAAATTCTG TATGTCATAC AGCAACTGTA ATAGCAAACT CATTCATGCA CTGTGGGACT 
ACCAGTGACC AGTTCCTTAG AGATAACTTG GAATGGCTGG CCAGAGCCAC TAACTGGGCC 
AAATTTACTG CAACTGCCAG CTTGGGTGTA ATCCATAAGG GCCATGAGAA GGAAGCACTA 
CAGTTAATGG CAACATACCT CCCTAAGGAC ACTTCTCCAG GATCAGCCTA TCAGGAAGGT 
GGAGGTCTCT ATGCATTGGG TCTCATTCAT GCCAATCATG GTGGTGACAT AATTGACTAT 
CTCCTTAATC AGCTCAAGAA TGCCAGCAAT GATATCGTTA GACATGGAGG CAGCTTGGGC 
CTTGGTTTGG CTGCAATGGG AACTGCACGT CAGGATGTAT ATGATTTGCT GAAAACAAAC 
CTGTATCAGG ATGATGCTGT GACAGGGGAG GCAGCTGGCC TGGCCTTAGG TTTGGTTATG 
TTAGGCTCTA AAAACACCCA GGCGATTGAG GATATGGTTG GCTATGCACA AGAAACTCAA 
CACGAGAAGA TTCTGCGTGG TCTAGCAGTT GGCATTGCGT TAGTGATGTA TGGGAGGATG 
GAGGAGGCCG ATGCTCTCAT TGAATCTCTC TGTCGTGATA AGGACCCAAT TCTTAGAAGA 
TCTGGAATGT ATACTGTAGC CATGGCTTAT TGTGGCTCTG GTAACAATAA AGCTATTCGA 
CGCCTGCTGC ATGTTGCTGT AAGTGATGTC AACGATGATG TCAGAAGAGC AGCAGTAGAG 
TCTCTTGGCT TCATTTTGTT CAGGACGCCT GAACAGTGTC CAAGTGTGGT CTCTTTGTTG 
TCCGAGAGTT ATAACCCTCA TGTGCGCTAC GGCGCTGCAA TGGCCCTGGG AGTCTGCTGT 
GCTGGTACAG GAAACAAGGA AGCAATTAAT TTACTGGAGC CAATGACCAA TGACCCTGTG 
AACTACGTGC GGCAAGGGGC TCTGATAGCC TCAGCTCTCA TCATGATCCA ACAGACCGAA 
ATCACGTGTC CAAAGGTAAA CCAGTTCCGG CAGCTGTATT CCAAAGTCAT CAATGACAAG 
CATGATGATG TCATGGCCAA ATTTGGCGCT ATTCTGGCCC AAGGCATACT GGATGCAGGT 
GGTCATAATG TCACAATCTC CTTACAGTCC AGGACTGGGC ACACTCATAT GCCTTCTGTG 
GTTGGCGTCC TTGTCTTTAC CCAGTTCTGG TTCTGGTTTC CCCTTTCACA CTTCCTATCA 
TTGGCTTATA CTCCTACCTG TATCATCGGC CTTAACAAGG ATTTAAAGAT GCCGAAAGTT 
CAATATAAAT CAAATTGTAA ACCATCCACA TTCGCATACC CTGCCCCTCT GGAAGTTCCA 
AAAGAAAAAG AAAAGGAAAA GGTTTCCACC GCTGTGTTGT CTATTACTGC CAAAGCTAAA 
AAAAAAGAAA AAGAAAAAGA AAAAAAGGAG GAGGAGAAGA TGGAAGTGGA CGAAGCAGAA 
AAGAAGGAAG AGAAAGAGAA GAAAAAAGAA CCGGAACCAA ACTTCCAGCT GTTGGATAAT 
CCAGCACGGG TCATGCCTGC CCAGCTGAAG GTCTTAAGTA TGACAGAGAC CTGCAGATAC 
CAACCCTTCA AGCCACTCTC CATCGGGGGC ATCATAATTC TGAAAGACAC CAGCGAAGAC 
ATTGAGGAAC TTGTGGAACC CGTGGCAGCA CATGGCCCAA AGATTGAAGA GGAGGAGCAG 
GAGCCAGAGC CCCCAGAGCC ATTTGAGTAC ATCGATGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114184.1
CDS	41..2902
Translation	MITSAAGIISLLDEEEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDTQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGPEKDSDSMETEEKTAGAVAGKTPDASPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNTQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGVCCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCIIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLSMTETCRYQPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD

Target ORF information:

RefSeq Version	NM_031978.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus proteasome 26S subunit, non-ATPase 1 (Psmd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031978.1

ORF Insert Sequence:

ATGATCACTT CAGCCGCTGG AATTATTTCT CTTCTGGATG AAGAAGAGCC ACAGCTCAAG 
GAATTTGCAC TACACAAATT GAATGCAGTT GTGAATGACT TCTGGGCAGA AATTTCTGAG 
TCTGTAGACA AAATAGAAGT TTTATATGAA GATGAAGGTT TCCGCAGTCG GCAGTTTGCA 
GCCTTGGTGG CATCGAAAGT ATTTTATCAC CTGGGGGCTT TCGAGGAGTC TCTGAATTAT 
GCTCTTGGAG CAGGTGACCT CTTCAATGTC AATGATAACT CTGAATATGT GGAGACTATT 
ATAGCAAAAT GCATTGATCA TTATACCAAA CAGTGTGTGG AAAATGCAGA TTTGCCTGAA 
GGAGAAAAGA AGCCAATTGA CCAGAGATTG GAAGGCATCG TGAATAAGAT GTTCCAGCGA 
TGTCTCGATG ATCACAAGTA TAAGCAAGCG ATTGGCATTG CTCTGGAGAC CAGGAGACTA 
GATGTGTTTG AGAAGACTAT ACTGGAATCT AATGATGTCC CAGGAATGCT AGCTTACAGC 
CTCAAGCTCT GCATGTCTTT AATGCAGAAT AAGCAGTTTC GGAATAAAGT ATTGCGAGTC 
CTGGTTAAAA TCTACATGAA CTTGGAAAAA CCTGATTTCA TCAATGTTTG TCAGTGCTTA 
ATCTTCTTAG ATGACACCCA GGCCGTGAGT GATATCTTAG AAAAGCTGGT AAAGGAAGAC 
AACCTGCTGA TGGCCTATCA GATTTGCTTT GATTTGTACG AAAGTGCCAG CCAGCAGTTT 
TTGTCATCTG TGATCCAGAA TCTTCGAACT GTTGGGACCC CTATTGCTTC TGTGCCTGGA 
TCTACCAATA CGGGTACTGT GCCAGGACCA GAGAAAGACA GTGACTCTAT GGAGACCGAG 
GAGAAGACAG CCGGTGCAGT GGCAGGGAAA ACACCAGACG CTAGTCCAGA GCCCAAGGAC 
CAGACATTGA AAATGATTAA AATTTTAAGT GGTGAAATGG CTATCGAGTT ACACCTGCAG 
TTCCTAATAC GCAATAATAA CACAGACCTC ATGATTCTGA AAAACACAAA GGATGCAGTA 
CGAAATTCTG TATGTCATAC AGCAACTGTA ATAGCAAACT CATTCATGCA CTGTGGGACT 
ACCAGTGACC AGTTCCTTAG AGATAACTTG GAATGGCTGG CCAGAGCCAC TAACTGGGCC 
AAATTTACTG CAACTGCCAG CTTGGGTGTA ATCCATAAGG GCCATGAGAA GGAAGCACTA 
CAGTTAATGG CAACATACCT CCCTAAGGAC ACTTCTCCAG GATCAGCCTA TCAGGAAGGT 
GGAGGTCTCT ATGCATTGGG TCTCATTCAT GCCAATCATG GTGGTGACAT AATTGACTAT 
CTCCTTAATC AGCTCAAGAA TGCCAGCAAT GATATCGTTA GACATGGAGG CAGCTTGGGC 
CTTGGTTTGG CTGCAATGGG AACTGCACGT CAGGATGTAT ATGATTTGCT GAAAACAAAC 
CTGTATCAGG ATGATGCTGT GACAGGGGAG GCAGCTGGCC TGGCCTTAGG TTTGGTTATG 
TTAGGCTCTA AAAACACCCA GGCGATTGAG GATATGGTTG GCTATGCACA AGAAACTCAA 
CACGAGAAGA TTCTGCGTGG TCTAGCAGTT GGCATTGCGT TAGTGATGTA TGGGAGGATG 
GAGGAGGCCG ATGCTCTCAT TGAATCTCTC TGTCGTGATA AGGACCCAAT TCTTAGAAGA 
TCTGGAATGT ATACTGTAGC CATGGCTTAT TGTGGCTCTG GTAACAATAA AGCTATTCGA 
CGCCTGCTGC ATGTTGCTGT AAGTGATGTC AACGATGATG TCAGAAGAGC AGCAGTAGAG 
TCTCTTGGCT TCATTTTGTT CAGGACGCCT GAACAGTGTC CAAGTGTGGT CTCTTTGTTG 
TCCGAGAGTT ATAACCCTCA TGTGCGCTAC GGCGCTGCAA TGGCCCTGGG AGTCTGCTGT 
GCTGGTACAG GAAACAAGGA AGCAATTAAT TTACTGGAGC CAATGACCAA TGACCCTGTG 
AACTACGTGC GGCAAGGGGC TCTGATAGCC TCAGCTCTCA TCATGATCCA ACAGACCGAA 
ATCACGTGTC CAAAGGTAAA CCAGTTCCGG CAGCTGTATT CCAAAGTCAT CAATGACAAG 
CATGATGATG TCATGGCCAA ATTTGGCGCT ATTCTGGCCC AAGGCATACT GGATGCAGGT 
GGTCATAATG TCACAATCTC CTTACAGTCC AGGACTGGGC ACACTCATAT GCCTTCTGTG 
GTTGGCGTCC TTGTCTTTAC CCAGTTCTGG TTCTGGTTTC CCCTTTCACA CTTCCTATCA 
TTGGCTTATA CTCCTACCTG TATCATCGGC CTTAACAAGG ATTTAAAGAT GCCGAAAGTT 
CAATATAAAT CAAATTGTAA ACCATCCACA TTCGCATACC CTGCCCCTCT GGAAGTTCCA 
AAAGAAAAAG AAAAGGAAAA GGTTTCCACC GCTGTGTTGT CTATTACTGC CAAAGCTAAA 
AAAAAAGAAA AAGAAAAAGA AAAAAAGGAG GAGGAGAAGA TGGAAGTGGA CGAAGCAGAA 
AAGAAGGAAG AGAAAGAGAA GAAAAAAGAA CCGGAACCAA ACTTCCAGCT GTTGGATAAT 
CCAGCACGGG TCATGCCTGC CCAGCTGAAG GTCTTAAGTA TGACAGAGAC CTGCAGATAC 
CAACCCTTCA AGCCACTCTC CATCGGGGGC ATCATAATTC TGAAAGACAC CAGCGAAGAC 
ATTGAGGAAC TTGTGGAACC CGTGGCAGCA CATGGCCCAA AGATTGAAGA GGAGGAGCAG 
GAGCCAGAGC CCCCAGAGCC ATTTGAGTAC ATCGATGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

Protein aggregation and proteasome dysfunction after brain ischemia.
Stroke38(12)3230-6(2007 Dec)
Ge P,Luo Y,Liu CL,Hu B

The cyclophilin-like domain of Ran-binding protein-2 modulates selectively the activity of the ubiquitin-proteasome system and protein biogenesis.
The Journal of biological chemistry282(48)34770-8(2007 Nov)
Yi H,Friedman JL,Ferreira PA

Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.
Biochemistry46(11)3553-65(2007 Mar)
Wang X,Chen CF,Baker PR,Chen PL,Kaiser P,Huang L

An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity.
Molecular cell23(6)875-85(2006 Sep)
Stanhill A,Haynes CM,Zhang Y,Min G,Steele MC,Kalinina J,Martinez E,Pickart CM,Kong XP,Ron D

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Psmd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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