Itpr2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itpr2
Entrez Gene ID	81678
Full Name	inositol 1,4,5-trisphosphate receptor, type 2
General protein information	Preferred Names inositol 1,4,5-trisphosphate receptor, type 2 Names inositol 1,4,5-trisphosphate receptor type 2 IP3 receptor IP3R 2 inositol 1,4,5-triphosphate receptor 2 inositol 1,4,5-triphosphate receptor, type 2 inositol triphosphate receptor type 2 insP3R2 type 2 InsP3 receptor type 2 inositol 1,4,5-trisphosphate receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q44
Summary	receptor for inositol 1,4,5-triphosphate; involved in regulating intracellular Ca(2+) concentration [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031046.3	NP_112308.1	inositol 1,4,5-trisphosphate receptor type 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ITPR2	XP_852399.1
	ITPR2	XP_001102937.1
Mus musculus (house mouse)	Itpr2	NP_064307.2
Gallus gallus (chicken)	ITPR2	XP_001235613.3
Pan troglodytes (chimpanzee)	ITPR2	XP_003313863.1
Bos taurus (cattle)	ITPR2	NP_776794.1
Homo sapiens (human)	ITPR2	NP_002214.2
Xenopus tropicalis (tropical clawed frog)	itpr2	XP_002943299.2
Rattus norvegicus (Norway rat)	Itpr2	NP_112308.1

Gene Ontology
Bibliography

Related articles in PubMed

Type 2 inositol trisphosphate receptor gene expression in hepatocytes is regulated by cyclic AMP.
Kruglov E, Ananthanarayanan M, Sousa P, Weerachayaphorn J, Guerra MT, Nathanson MH
Biochemical and biophysical research communications486(3)659-664(2017 05)

Calcineurin-NFATc regulates type 2 inositol 1,4,5-trisphosphate receptor (InsP3R2) expression during cardiac remodeling.
Sankar N, deTombe PP, Mignery GA
The Journal of biological chemistry289(9)6188-98(2014 Feb)

The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.
Schulman JJ, Wright FA, Kaufmann T, Wojcikiewicz RJ
The Journal of biological chemistry288(35)25340-9(2013 Aug)

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)

Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy.
Drawnel FM, Wachten D, Molkentin JD, Maillet M, Aronsen JM, Swift F, Sjaastad I, Liu N, Catalucci D, Mikoshiba K, Hisatsune C, Okkenhaug H, Andrews SR, Bootman MD, Roderick HL
The Journal of cell biology199(5)783-98(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The findings provide evidence that IP3R2 expression is transcriptionally regulated by cyclic AMP via CREB binding to CRE elements in its promoter.
Title: Type 2 inositol trisphosphate receptor gene expression in hepatocytes is regulated by cyclic AMP.

ITPR2 and hypertrophy specific gene expression is regulated, in part, by a positive feedback regulation between InsP3R2 and calcineurin-NFATc signaling pathways.
Title: Calcineurin-NFATc regulates type 2 inositol 1,4,5-trisphosphate receptor (InsP3R2) expression during cardiac remodeling.

Inositol 1,4,5-trisphosphate and IP3 receptors act as inhibitors of autophagic processes in cardiomyocytes.
Title: Regulation of autophagy in cardiomyocytes by Ins(1,4,5)P(3) and IP(3)-receptors.

Pericanalicular calcium signaling mediated InsP3R2 plays an important role in maintaining bile salt secretion through posttranslational regulation of the bile salt export pump.
Title: Type 2 inositol 1,4,5-trisphosphate receptor modulates bile salt export pump activity in rat hepatocytes.

IP(3)R2 selectively associates with AC6, G alpha(s) also associates with the AC x IP(3)R signaling junction.
Title: Regulation of inositol 1,4,5-trisphosphate receptors by cAMP independent of cAMP-dependent protein kinase.

The following Itpr2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itpr2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13104	NM_031046.3 Latest version!	Rattus norvegicus inositol 1,4,5-trisphosphate receptor, type 2 (Itpr2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itpr2 ( NM_031046.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112308.1 Rattus norvegicus inositol 1,4,5-trisphosphate receptor, type 2 (Itpr2), mRNA.

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CloneID	ORa13104
Clone ID Related Accession (Same CDS sequence)	NM_031046.3
Accession Version	NM_031046.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 8106bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	inositol 1,4,5-trisphosphate receptor type 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X61677.1. On Nov 2, 2002 this sequence version replaced NM_031046.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X61677.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCTGACA AAATGTCCAG CTTCCTCTAC ATTGGGGACA TCGTGTCCCT GTACGCGGAG 
GGCTCGGTCA ATGGCTTCAT CAGCACCCTG GGGTTGGTGG ATGACCGTTG TGTGGTGCAC 
CCGGAGGCGG GGGATCTTAC CAACCCACCC AAGAAGTTCA GAGACTGCCT CTTCAAGGTG 
TGCCCCATGA ATCGATACTC TGCCCAGAAG CAGTACTGGA AAGCCAAGCA GGCGAAGCAG 
GGAAACCACA CGGAGGCTGC CCTGCTGAAG AAGCTCCAGC ACGCCGCAGA GCTGGAACAA 
AAACAGAATG AGTCAGAGAA CAGGAAACTT TTGGGAGAAA TTGTGAAATA CAGCAAAGTT 
ATACAACTAC TGCACATAAA AAGCAACAAG TACCTCACCG TGAACAAGAG GTTACCTGCC 
TTACTGGAGA AGAATGCCAT GCGTGTGTCC CTGGATGCTG CAGGGAACGA AGGGTCCTGG 
TTCTACATCC ATCCCTTCTG GAAGCTGAGA AGCGAGGGTG ATAATATCGT CGTGGGAGAT 
AAAGTCGTTC TGATGCCTGT AAATGCTGGG CAGCCCCTGC ATGCCAGCAA CGTGGAGCTC 
CTGGACAACC CCGGCTGCAA AGAGGTGAAT GCTGTTAATT GCAACACTAG CTGGAAAATC 
ACTTTATTCA TGAAGTTCAG CTCCTACCGA GAGGATGTAT TAAAAGGGGG TGACGTTGTG 
AGACTGTTTC ATGCGGAACA AGAGAAGTTT CTGACCTGTG ATGACTATGA GAAAAAACAG 
CACATTTTCC TGCGGACGAC CTTGCGTCAA TCAGCAACGT CGGCCACTAG CTCTAAAGCA 
CTCTGGGAGA TAGAGGTGGT TCACCATGAT CCATGCCGCG GAGGTGCAGG ACAGTGGAAC 
AGCCTGTTCA GGTTTAAGCA TCTTGCAACT GGGAACTACT TAGCTGCAGA GCTTAACCCT 
GACTATCGAG ATGCTCAAAA TGAAGGAAAA ACTGTGAGAG ACGGGGAGCT TCCAACCTCA 
AAGAAAAAAC ACCAGGCAGG GGAGAAGATC ATGTACACGC TGGTCTCGGT CCCGCACGGA 
AATGACATCG CGTCCCTTTT TGAACTTGAC GCCACAACTC TGCAGAGAGC TGACTGCCTG 
GTTCCGAGGA ACTCCTACGT GCGGTTGAGG CACCTGTGTA CCAACACGTG GGTAACAAGC 
ACCAGCATCC CCATAGACAC GGAGGAAGAG AGGCCTGTCA TGCTGAAAAT TGGGACCTGC 
CAGACCAAGG AAGACAAAGA AGCCTTTGCC ATCGTGTGCG TCCCGCTGTC TGAGGTCCGA 
GACCTGGACT TTGCCAACGA TGCCAACAAA GTGTTGGCCA CCACGGTGAA GAAGCTGGAG 
AACGGCAGCA TCACCCAGAA TGAGAGGAGG TTTGTGACTA AGTTGTTGGA AGACCTTATT 
TTCTTTGTGG CTGATGTGAC CAACAACGGA CAGGATGTTC TGGATGTGGT CATCACCAAG 
CCCAACCGGG AACGGCAAAA ACTAATGAGG GAACAGAATA TTCTGGCACA GGTGTTTGGG 
ATCCTTAAAG CCCCTTTCAA GGAGAAGGCT GGGGAAGGCT CGATGCTGAG GCTGGAGGAC 
CTGGGCGACC AGCGCTATGC CCCGTACAAG TACGTGCTGC GTCTCTGCTA CCGTGTGCTG 
AGGCATTCGC AGCAGGACTA CAGGAAGAAC CAGGAGTACA TTGCTAAGAA CTTCTGCGTC 
ATGCAGTCTC AGATCGGCTA TGATATTTTG GCAGAAGATA CGATCACAGC CTTGCTACAC 
AACAACCGCA AACTCCTGGA GAAACACATC ACGGCCAAAG AAATCGAGAC CTTCGTCAGC 
CTGCTCAGGA GGAACCGGGA GCCGAGGTTT CTGGACTATC TGTCTGACCT CTGCGTGTCC 
AATAGCACCG CCATCCCTGT GACTCAGGAG CTCATCTGCA AATTCATGCT GAGCCCCGGC 
AATGCGGACA TCCTCATTCA GACGAAGCTG GTGTCCATGC AAGTGGAAAA CCCCATGGAG 
AGCTCCATCC TTCCCGATGA CATCGACGAC GAGGAGGTTT GGCTTTACTG GATTGACAGC 
AACAAGGAGC CTCACGGCAA GGCCATCAGG CACCTGGCCC AGGAGGCCAG GGAAGGCACC 
AAGGCTGACC TAGAAGTCCT GACCTATTAC AGGTACCAGC TAAACCTCTT TGCAAGGATG 
TGCTTGGACC GCCAGTACCT GGCCATCAAC CAGATTTCAA CACAGCTGTC TGTAGACCTG 
ATCCTGCGGT GCGTGTCTGA CGAGAGCCTG CCCTTTGACC TCCGAGCCTC TTTCTGCCGA 
CTCATGCTCC ACATGCATGT GGACCGGGAC CCCCAGGAGT CTGTGGTGCC TGTCCGCTAC 
GCCCGGCTCT GGACTGAGAT CCCCACCAAG ATCACGATCC ATGAGTATGA CTCCATCACA 
GACTCTTCCA GAAATGACAT GAAGAGGAAG TTTGCCCTGA CAATGGAATT TGTCGAAGAA 
TATTTGAAAG AAGTTGTGAA TCAACCGTTT CCTTTTGGGG ACAAAGAGAA AAATAAACTG 
ACATTTGAGG TGGTCCACCT GGCCCGGAAC CTCATCTACT TCGGATTCTA CAGCTTCAGC 
GAGTTGCTGC GGCTGACGAG AACTCTGCTG GCGATCCTGG ACATCGTCCA GGCCCCCATG 
TCGTCGTATT TTGAAAGATT AAGCAAGTTT CAAGATGGAA GCAACAATGT CATGAGGACC 
ATCCACGGGG TGGGAGAGAT GATGACACAG ATGGTGCTCA GCAGAGGCTC CATTTTCCCA 
GTGAGCTGGC CCGACGCACA GCCCAGCGTC CACCCCAGCA AGCAGGCGAG CCCCGGCGAG 
CAGGAGGATG TGACGGTTAT GGATACCAAG CTAAAGGTTA TCGAGATTTT ACAGTTCATC 
CTGAGTGTCA GGCTGGACTA CCGTATCTCT TACATGCTGT CCATATACAA GAAGGAATTT 
GGGGAGAATG ATGGCAACGG TGACCCCTCT GCCAGCGGCA CCCCGGAAAC ATTGCTACCA 
TCAGCTCTTG TCCCTGACAT TGATGAGATT GCGGCTCAGG CAGAAACGAT GTTTGCTGGA 
AGAAAAGAAA AAACTCCAGT TCAGCTTGAT GATGAGGGAG GCAGAACCTT CTTAAGAGTC 
CTCATCCACC TGATCATGCA TGACTATGCT CCACTGCTGT CCGGGGCCCT GCAGCTGCTG 
TTCAAACACT TCAGCCAGAG AGCAGAAGTG CTTCAGGCCT TCAAACAGGT GCAGTTACTG 
GTGTCGAACC AAGATGTCGA TAACTACAAG CAAATCAAGG CAGACCTGGA CCAACTTCGG 
CTGACGGTGG AGAAGTCCGA GCTATGGGTG GAAAAGAGCG GCAGCTATGA GAATGGAGAC 
ATGGGCGAGG GCCAGGCCAA AGGAGGCGAA GAGGCAAACG AGGAGTCCAA CCTCTTGAGC 
CCGGTGCAGG ACGGCGCGAA GACACCTCAG ATCGACAGCA ACAAGGGCAA CAACTACCGG 
ATCGTCAAGG AGATCTTGAT TAGGCTGAGT AAGCTCTGTG TGCAGAACAA GAAATGTCGT 
AATCAACACC AACGGTTGCT GAAAAATATG GGGGCTCACT CCGTGGTACT GGACCTTCTG 
CAGATCCCCT ATGAGAAGAC CGACGAGAAG ATGAACGAGG TGATGGACTT AGCCCACACC 
TTCCTGCAGA ACTTCTGCCG CGGGAATCCA CAGAACCAAG TTCTCCTTCA CAAGCATCTC 
AACCTGTTCC TAACCCCTGG ACTCCTGGAG GCGGAAACCA TGCGGCACAT CTTCATGAAC 
AATTACCATC TGTGCAATGA GATCAGCGAG AGGGTGGTCC AGCACTTTGT GCACTGCATT 
GAGACACACG GCCGCCACGT GGAGTACCTG AGGTTCCTGC AGACCATCGT GAAAGCAGAC 
GGCAAATACG TGAAGAAATG CCAGGACATG GTGATGACCG AGCTGATCAA TGGGGGTGAA 
GACGTACTGA TATTCTACAA CGACCGAGCC TCATTTCCCA TCCTTCTCAA CATGATGTGC 
TCCGAGAGAG CCCGTGGGGA TGAGAGCGGC CCCCTGGCCT ACCATATCAC CCTTGTGGAG 
TTGCTGGCAG CGTGCACTGA GGGGAAGAAC GTCTACACGG AGATCAAGTG CAATTCTCTC 
TTGCCTCTGG ACGACATAGT GAGGGTGGTG ACCCACGACG ACTGCATTCC TGAGGTAAAA 
ATTGCATACG TGAACTTTGT CAACCATTGT TACGTTGACA CAGAAGTGGA GATGAAGGAA 
ATCTATACAA GTAACCACAT TTGGAAGTTA TTTGAGAACT TCTTGGTGGA TATGGCAAGG 
GTCTGCAACA CCACCACGGA CCGGAAACAC GCAGACACCT TTCTGGAGAG GTGTGTGACA 
GAGTCAGTCA TGAACATCGT GAGCGGCTTC TTCAACTCGC CGTTTTCGGA TAACAGTACC 
AGCCTCCAGA CCCATCAGCC GGTCTTTATC CAGCTGCTGC AGTCCGCCTT CAGAATTTAC 
AACTGCACCT GGCCCAACCC AGCCCAGAAA GCCTCCGTGG AATCCTGCAT CAGAGCCCTG 
GCTGAAGTGG CCAAAAACCG TGGGATTGCG ATTCCGGTGG ATTTGGACAG CCAGGTCAAC 
ACACTCTTCA TGAAGAATCA CTCAAGTACA GTGCAGAGGG CGGCCATGGG CTGGAGGCTC 
TCTGCTCGCT CCGGACCTCG CTTCAAGGAA GCTCTTGGAG GGCCAGCATG GGACTACAGG 
AATATTATTG AAAAGTTACA GGATGTCGTG GCCTCTCTGG AACAGCAGTT CAGCCCCATG 
ATGCAGGCTG AGTTCTCTGT GCTTGTGGAT GTGCTGTACA GCCCGGAGCT ACTGTTCCCA 
GAAGGAAGCG ATGCCAGGAT ACGATGTGGT GCCTTCATGT CCAAGCTGAT TAATCACACA 
AAGAAACTGA TGGAAAAAGA AGAAAAACTG TGCATTAAAA TCCTCCAGAC GTTACGGGAG 
ATGCTGGAGA AGAAAGACAG CTTCATGGAA GAGAGTAGCA CATTACGGAA AATCCTCCTG 
AATCGGTACT TCAAGGGTGA CCACAGCGTT GGTGTGAACG GACCTCTGTC AGGAGCCTAC 
GCCAAGACAG CACAAGTGGG AGGGGGCTTC ACTGGACAGG ATGCCGATAA GACGGGGATT 
TCCATGTCCG ATATCCAGTG TTTGCTGGAC AAGGAAGGGG CCTCCGAACT TGTCATCGAT 
GTCATTGTGA ACACCAAAAA CGACAGGATT TTTTCCGAGG GCATCTTGCT TGGCATTGCC 
CTGCTGGAAG GAGGAAACAC ACAAACCCAG AATTCTTTCT ACCAGCAGTT GCATGAACAA 
AAAAAGTCAG AGAAATTCTT CAAAGTCCTT TACGATCGGA TGAAGGCTGC TCAGAAAGAG 
ATCAGATCCA CGGTGACTGT CAACACCATA GACTTAGGGA GCAAGAAGAG AGAGGAGGAC 
AGTGACCTCA TGGCCTTGGG CCCTCGGATG AGAGTGAGAG ACTCATCGCT GCATTTGAAA 
GAGGGAATGA AAGGGCAGTT GACTGAGGCG TCTTCAGCCA CGTCCAAAGC ATACTGTGTG 
TACAGAAGGG AAATGGACCC AGACATTGAC ACGATGTGCC CGGGACAGGA AGCAGGAAGT 
GCGGAGGAAA AGTCTGCAGA GGAAGTTACC ATGAGCCCAG CCATCACTAT CATGCGGCCC 
ATCCTCAGGT TCCTGCAGTT ACTGTGTGAG AATCACAACC GGGAGCTTCA GAACTTCTTG 
AGGAACCAGA ACAACAAAAC AAACTACAAC CTTGTCTGTG AAACACTTCA GTTTCTGGAC 
TGCATCTGTG GAAGCACCAC AGGGGGCCTA GGCCTGCTGG GGCTCTACAT CAATGAGAAG 
AACGTAGCTC TGGTCAACCA GACCCTGGAG AGCTTGACCG AGTACTGCCA GGGCCCGTGT 
CATGAGAACC AGACCTGTAT CGCCACTCAC GAATCCAATG GGATTGACAT CATCATCGCC 
TTGATTCTGA GTGACATCAA CCCTCTGGGC AAGTACAGAA TGGACCTGGT GCTACAGCTG 
AAGAACAACG CCTCCAAGCT TCTGCTGGCC ATTATGGAGA GCAGACACGA CAGTGAGAAT 
GCAGAGAGAA TTCTCTTCAA CATGAGACCC AAGGAACTGG TGGATGTCAT GAAGAATGCC 
TATAACCAAG GCCTGGAATG TAACCATGGG GACGAGGAGG GAGGAGATGA TGGTGTTTCT 
CCAAAAGACG TTGGACACAA CATCTACATC CTGGCCCATC AGTTGGCCCG CCACAATAAA 
CTCCTACAGC AGATGCTCAA GCCTGGATCC GATCCAGAGG AAGGGGATGA AGCCTTGAAG 
TACTATGCCA ACCACACCGC ACAGATCGAG ATTGTGCGGC ACGACCGGAC TATGGAGCAG 
ATTGTTTTCC CCGTCCCCAA TATCTGCGAA TTCCTCACTC GGGAATCCAA ATACCGGGTG 
TTCAACACAA CGGAGAGGGA TGAGCAAGGA AGCAAGGTGA ACGACTTCTT CCAGCAAACG 
GAAGATCTCT ACAACGAGAT GAAATGGCAA AAGAAGATCA GGAACAACCC CGCCCTGTTC 
TGGTTCTCCA GGCACATCTC CCTGTGGGGG AGCATCTCCT TCAACCTGGC TGTGTTCATC 
AACCTGGCCG TGGCTCTCTT CTACCCATTC GGGGATGACG GCGATGAAGG TACGCTCTCC 
CCGCTGTTCT CAGCCCTCCT TTGGGTAGCA GTGGCGATCT GCACGTCTAT GCTGTTCTTC 
TTCTCCAAGC CTGTGGGCAT CCGGCCATTC CTTGTGTCTA TCATGCTCAG ATCAATATAC 
ACCATCGGTC TGGGGCCAAC GCTAATACTT CTTGGTGCTG CCAATCTATG CAATAAAATC 
GTGTTCCTGG TGAGTTTTGT GGGAAACCGA GGCACATTCA CCCGAGGGTA CCGAGCAGTC 
ATTCTGGACA TGGCCTTTCT TTACCACGTG GCCTATGTCT TGGTTTGCAT GCTTGGCCTC 
TTCGTCCACG AGTTCTTCTA CAGCTTCCTG CTTTTTGACT TGGTGTACAG AGAAGAGACC 
CTGCTGAACG TCATCAAAAG CGTCACACGG AATGGCCGCT CCATCATCCT GACTGCGGTC 
TTGGCTCTTA TCCTGGTCTA CCTGTTCTCC ATCATCGGCT TCCTTTTCTT AAAGGATGAC 
TTCACCATGG AGGTGGACAG ATTGAAAAAC AGAACTCCAG TCACAGGTAA CGACGGGGTT 
CCCACTATGA CCTTAACTTC CATGCTGGGA ACCTGCCCTA AGGAAAACTG CTCACCCACG 
ATCCCCTCTT CGAATGCAGC CGGTGAGGGA GGTGAGGACG GCATCGAGAG GACCTGTGAC 
ACCCTGCTCA TGTGCATTGT CACCGTGCTG AACCAGGGCC TCAGGAATGG TGGCGGAGTT 
GGTGACGTGC TGAGACGACC CTCGAAGGAT GAGCCTTTGT TTGCTGCCCG GGTGGTCTAC 
GACCTCCTTT TCTTCTTCAT CGTCATCATC ATCGTCCTTA ACCTGATTTT TGGTGTAATC 
ATTGACACTT TCGCTGACCT CAGGAGTGAG AAGCAGAAGA AAGAAAAAAT TCTCAAGACA 
ACCTGCTTCA TCTGTGGCTT GGAGAGGGAC AAGTTTGATA ACAAGACGGT GTCCTTTGAG 
GAGCACATCA AGTCAGAGCA CAACATGTGG CATTACTTGT ACTTCATCGT CCTGGTGAAG 
GTGAAGGACC CAACAGAATA CACAGGGCCT GAGAGCTACG TGGCTCAGAT GATCACAGAG 
AAGAATTTAG ACTGGTTTCC TCGGATGCGA GCCATGTCAC TTGTCAGCAA TGAAGGTGAC 
AGTGAGCAAA ATGAGATCCG GAACCTGCAG GAGAAGCTGG AGTCCACTAT GAGTCTGGTG 
AAACAGTTGT CGGGGCAGCT GGCAGAGCTG AAGGAGCAGA TGACAGAACA AAGGAAAAAC 
AAGCAAAGGC TGGGCTTCCT TGGATCAAAC ACACCCCATG AGAACCATCA CATGCCACCG 
CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112308.1
CDS	247..8352
Translation	MSDKMSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAGDLTNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENRKLLGEIVKYSKVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQPLHASNVELLDNPGCKEVNAVNCNTSWKITLFMKFSSYREDVLKGGDVVRLFHAEQEKFLTCDDYEKKQHIFLRTTLRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKTVRDGELPTSKKKHQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKKLENGSITQNERRFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPMESSILPDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSWPDAQPSVHPSKQASPGEQEDVTVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFGENDGNGDPSASGTPETLLPSALVPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSGSYENGDMGEGQAKGGEEANEESNLLSPVQDGAKTPQIDSNKGNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKTDEKMNEVMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSLQTHQPVFIQLLQSAFRIYNCTWPNPAQKASVESCIRALAEVAKNRGIAIPVDLDSQVNTLFMKNHSSTVQRAAMGWRLSARSGPRFKEALGGPAWDYRNIIEKLQDVVASLEQQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQTLREMLEKKDSFMEESSTLRKILLNRYFKGDHSVGVNGPLSGAYAKTAQVGGGFTGQDADKTGISMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGILLGIALLEGGNTQTQNSFYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGSKKREEDSDLMALGPRMRVRDSSLHLKEGMKGQLTEASSATSKAYCVYRREMDPDIDTMCPGQEAGSAEEKSAEEVTMSPAITIMRPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILSDINPLGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPKELVDVMKNAYNQGLECNHGDEEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPEEGDEALKYYANHTAQIEIVRHDRTMEQIVFPVPNICEFLTRESKYRVFNTTERDEQGSKVNDFFQQTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDEGTLSPLFSALLWVAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAANLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNDGVPTMTLTSMLGTCPKENCSPTIPSSNAAGEGGEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEKILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGSNTPHENHHMPPH

Target ORF information:

RefSeq Version	NM_031046.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus inositol 1,4,5-trisphosphate receptor, type 2 (Itpr2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031046.3

ORF Insert Sequence:

ATGTCTGACA AAATGTCCAG CTTCCTCTAC ATTGGGGACA TCGTGTCCCT GTACGCGGAG 
GGCTCGGTCA ATGGCTTCAT CAGCACCCTG GGGTTGGTGG ATGACCGTTG TGTGGTGCAC 
CCGGAGGCGG GGGATCTTAC CAACCCACCC AAGAAGTTCA GAGACTGCCT CTTCAAGGTG 
TGCCCCATGA ATCGATACTC TGCCCAGAAG CAGTACTGGA AAGCCAAGCA GGCGAAGCAG 
GGAAACCACA CGGAGGCTGC CCTGCTGAAG AAGCTCCAGC ACGCCGCAGA GCTGGAACAA 
AAACAGAATG AGTCAGAGAA CAGGAAACTT TTGGGAGAAA TTGTGAAATA CAGCAAAGTT 
ATACAACTAC TGCACATAAA AAGCAACAAG TACCTCACCG TGAACAAGAG GTTACCTGCC 
TTACTGGAGA AGAATGCCAT GCGTGTGTCC CTGGATGCTG CAGGGAACGA AGGGTCCTGG 
TTCTACATCC ATCCCTTCTG GAAGCTGAGA AGCGAGGGTG ATAATATCGT CGTGGGAGAT 
AAAGTCGTTC TGATGCCTGT AAATGCTGGG CAGCCCCTGC ATGCCAGCAA CGTGGAGCTC 
CTGGACAACC CCGGCTGCAA AGAGGTGAAT GCTGTTAATT GCAACACTAG CTGGAAAATC 
ACTTTATTCA TGAAGTTCAG CTCCTACCGA GAGGATGTAT TAAAAGGGGG TGACGTTGTG 
AGACTGTTTC ATGCGGAACA AGAGAAGTTT CTGACCTGTG ATGACTATGA GAAAAAACAG 
CACATTTTCC TGCGGACGAC CTTGCGTCAA TCAGCAACGT CGGCCACTAG CTCTAAAGCA 
CTCTGGGAGA TAGAGGTGGT TCACCATGAT CCATGCCGCG GAGGTGCAGG ACAGTGGAAC 
AGCCTGTTCA GGTTTAAGCA TCTTGCAACT GGGAACTACT TAGCTGCAGA GCTTAACCCT 
GACTATCGAG ATGCTCAAAA TGAAGGAAAA ACTGTGAGAG ACGGGGAGCT TCCAACCTCA 
AAGAAAAAAC ACCAGGCAGG GGAGAAGATC ATGTACACGC TGGTCTCGGT CCCGCACGGA 
AATGACATCG CGTCCCTTTT TGAACTTGAC GCCACAACTC TGCAGAGAGC TGACTGCCTG 
GTTCCGAGGA ACTCCTACGT GCGGTTGAGG CACCTGTGTA CCAACACGTG GGTAACAAGC 
ACCAGCATCC CCATAGACAC GGAGGAAGAG AGGCCTGTCA TGCTGAAAAT TGGGACCTGC 
CAGACCAAGG AAGACAAAGA AGCCTTTGCC ATCGTGTGCG TCCCGCTGTC TGAGGTCCGA 
GACCTGGACT TTGCCAACGA TGCCAACAAA GTGTTGGCCA CCACGGTGAA GAAGCTGGAG 
AACGGCAGCA TCACCCAGAA TGAGAGGAGG TTTGTGACTA AGTTGTTGGA AGACCTTATT 
TTCTTTGTGG CTGATGTGAC CAACAACGGA CAGGATGTTC TGGATGTGGT CATCACCAAG 
CCCAACCGGG AACGGCAAAA ACTAATGAGG GAACAGAATA TTCTGGCACA GGTGTTTGGG 
ATCCTTAAAG CCCCTTTCAA GGAGAAGGCT GGGGAAGGCT CGATGCTGAG GCTGGAGGAC 
CTGGGCGACC AGCGCTATGC CCCGTACAAG TACGTGCTGC GTCTCTGCTA CCGTGTGCTG 
AGGCATTCGC AGCAGGACTA CAGGAAGAAC CAGGAGTACA TTGCTAAGAA CTTCTGCGTC 
ATGCAGTCTC AGATCGGCTA TGATATTTTG GCAGAAGATA CGATCACAGC CTTGCTACAC 
AACAACCGCA AACTCCTGGA GAAACACATC ACGGCCAAAG AAATCGAGAC CTTCGTCAGC 
CTGCTCAGGA GGAACCGGGA GCCGAGGTTT CTGGACTATC TGTCTGACCT CTGCGTGTCC 
AATAGCACCG CCATCCCTGT GACTCAGGAG CTCATCTGCA AATTCATGCT GAGCCCCGGC 
AATGCGGACA TCCTCATTCA GACGAAGCTG GTGTCCATGC AAGTGGAAAA CCCCATGGAG 
AGCTCCATCC TTCCCGATGA CATCGACGAC GAGGAGGTTT GGCTTTACTG GATTGACAGC 
AACAAGGAGC CTCACGGCAA GGCCATCAGG CACCTGGCCC AGGAGGCCAG GGAAGGCACC 
AAGGCTGACC TAGAAGTCCT GACCTATTAC AGGTACCAGC TAAACCTCTT TGCAAGGATG 
TGCTTGGACC GCCAGTACCT GGCCATCAAC CAGATTTCAA CACAGCTGTC TGTAGACCTG 
ATCCTGCGGT GCGTGTCTGA CGAGAGCCTG CCCTTTGACC TCCGAGCCTC TTTCTGCCGA 
CTCATGCTCC ACATGCATGT GGACCGGGAC CCCCAGGAGT CTGTGGTGCC TGTCCGCTAC 
GCCCGGCTCT GGACTGAGAT CCCCACCAAG ATCACGATCC ATGAGTATGA CTCCATCACA 
GACTCTTCCA GAAATGACAT GAAGAGGAAG TTTGCCCTGA CAATGGAATT TGTCGAAGAA 
TATTTGAAAG AAGTTGTGAA TCAACCGTTT CCTTTTGGGG ACAAAGAGAA AAATAAACTG 
ACATTTGAGG TGGTCCACCT GGCCCGGAAC CTCATCTACT TCGGATTCTA CAGCTTCAGC 
GAGTTGCTGC GGCTGACGAG AACTCTGCTG GCGATCCTGG ACATCGTCCA GGCCCCCATG 
TCGTCGTATT TTGAAAGATT AAGCAAGTTT CAAGATGGAA GCAACAATGT CATGAGGACC 
ATCCACGGGG TGGGAGAGAT GATGACACAG ATGGTGCTCA GCAGAGGCTC CATTTTCCCA 
GTGAGCTGGC CCGACGCACA GCCCAGCGTC CACCCCAGCA AGCAGGCGAG CCCCGGCGAG 
CAGGAGGATG TGACGGTTAT GGATACCAAG CTAAAGGTTA TCGAGATTTT ACAGTTCATC 
CTGAGTGTCA GGCTGGACTA CCGTATCTCT TACATGCTGT CCATATACAA GAAGGAATTT 
GGGGAGAATG ATGGCAACGG TGACCCCTCT GCCAGCGGCA CCCCGGAAAC ATTGCTACCA 
TCAGCTCTTG TCCCTGACAT TGATGAGATT GCGGCTCAGG CAGAAACGAT GTTTGCTGGA 
AGAAAAGAAA AAACTCCAGT TCAGCTTGAT GATGAGGGAG GCAGAACCTT CTTAAGAGTC 
CTCATCCACC TGATCATGCA TGACTATGCT CCACTGCTGT CCGGGGCCCT GCAGCTGCTG 
TTCAAACACT TCAGCCAGAG AGCAGAAGTG CTTCAGGCCT TCAAACAGGT GCAGTTACTG 
GTGTCGAACC AAGATGTCGA TAACTACAAG CAAATCAAGG CAGACCTGGA CCAACTTCGG 
CTGACGGTGG AGAAGTCCGA GCTATGGGTG GAAAAGAGCG GCAGCTATGA GAATGGAGAC 
ATGGGCGAGG GCCAGGCCAA AGGAGGCGAA GAGGCAAACG AGGAGTCCAA CCTCTTGAGC 
CCGGTGCAGG ACGGCGCGAA GACACCTCAG ATCGACAGCA ACAAGGGCAA CAACTACCGG 
ATCGTCAAGG AGATCTTGAT TAGGCTGAGT AAGCTCTGTG TGCAGAACAA GAAATGTCGT 
AATCAACACC AACGGTTGCT GAAAAATATG GGGGCTCACT CCGTGGTACT GGACCTTCTG 
CAGATCCCCT ATGAGAAGAC CGACGAGAAG ATGAACGAGG TGATGGACTT AGCCCACACC 
TTCCTGCAGA ACTTCTGCCG CGGGAATCCA CAGAACCAAG TTCTCCTTCA CAAGCATCTC 
AACCTGTTCC TAACCCCTGG ACTCCTGGAG GCGGAAACCA TGCGGCACAT CTTCATGAAC 
AATTACCATC TGTGCAATGA GATCAGCGAG AGGGTGGTCC AGCACTTTGT GCACTGCATT 
GAGACACACG GCCGCCACGT GGAGTACCTG AGGTTCCTGC AGACCATCGT GAAAGCAGAC 
GGCAAATACG TGAAGAAATG CCAGGACATG GTGATGACCG AGCTGATCAA TGGGGGTGAA 
GACGTACTGA TATTCTACAA CGACCGAGCC TCATTTCCCA TCCTTCTCAA CATGATGTGC 
TCCGAGAGAG CCCGTGGGGA TGAGAGCGGC CCCCTGGCCT ACCATATCAC CCTTGTGGAG 
TTGCTGGCAG CGTGCACTGA GGGGAAGAAC GTCTACACGG AGATCAAGTG CAATTCTCTC 
TTGCCTCTGG ACGACATAGT GAGGGTGGTG ACCCACGACG ACTGCATTCC TGAGGTAAAA 
ATTGCATACG TGAACTTTGT CAACCATTGT TACGTTGACA CAGAAGTGGA GATGAAGGAA 
ATCTATACAA GTAACCACAT TTGGAAGTTA TTTGAGAACT TCTTGGTGGA TATGGCAAGG 
GTCTGCAACA CCACCACGGA CCGGAAACAC GCAGACACCT TTCTGGAGAG GTGTGTGACA 
GAGTCAGTCA TGAACATCGT GAGCGGCTTC TTCAACTCGC CGTTTTCGGA TAACAGTACC 
AGCCTCCAGA CCCATCAGCC GGTCTTTATC CAGCTGCTGC AGTCCGCCTT CAGAATTTAC 
AACTGCACCT GGCCCAACCC AGCCCAGAAA GCCTCCGTGG AATCCTGCAT CAGAGCCCTG 
GCTGAAGTGG CCAAAAACCG TGGGATTGCG ATTCCGGTGG ATTTGGACAG CCAGGTCAAC 
ACACTCTTCA TGAAGAATCA CTCAAGTACA GTGCAGAGGG CGGCCATGGG CTGGAGGCTC 
TCTGCTCGCT CCGGACCTCG CTTCAAGGAA GCTCTTGGAG GGCCAGCATG GGACTACAGG 
AATATTATTG AAAAGTTACA GGATGTCGTG GCCTCTCTGG AACAGCAGTT CAGCCCCATG 
ATGCAGGCTG AGTTCTCTGT GCTTGTGGAT GTGCTGTACA GCCCGGAGCT ACTGTTCCCA 
GAAGGAAGCG ATGCCAGGAT ACGATGTGGT GCCTTCATGT CCAAGCTGAT TAATCACACA 
AAGAAACTGA TGGAAAAAGA AGAAAAACTG TGCATTAAAA TCCTCCAGAC GTTACGGGAG 
ATGCTGGAGA AGAAAGACAG CTTCATGGAA GAGAGTAGCA CATTACGGAA AATCCTCCTG 
AATCGGTACT TCAAGGGTGA CCACAGCGTT GGTGTGAACG GACCTCTGTC AGGAGCCTAC 
GCCAAGACAG CACAAGTGGG AGGGGGCTTC ACTGGACAGG ATGCCGATAA GACGGGGATT 
TCCATGTCCG ATATCCAGTG TTTGCTGGAC AAGGAAGGGG CCTCCGAACT TGTCATCGAT 
GTCATTGTGA ACACCAAAAA CGACAGGATT TTTTCCGAGG GCATCTTGCT TGGCATTGCC 
CTGCTGGAAG GAGGAAACAC ACAAACCCAG AATTCTTTCT ACCAGCAGTT GCATGAACAA 
AAAAAGTCAG AGAAATTCTT CAAAGTCCTT TACGATCGGA TGAAGGCTGC TCAGAAAGAG 
ATCAGATCCA CGGTGACTGT CAACACCATA GACTTAGGGA GCAAGAAGAG AGAGGAGGAC 
AGTGACCTCA TGGCCTTGGG CCCTCGGATG AGAGTGAGAG ACTCATCGCT GCATTTGAAA 
GAGGGAATGA AAGGGCAGTT GACTGAGGCG TCTTCAGCCA CGTCCAAAGC ATACTGTGTG 
TACAGAAGGG AAATGGACCC AGACATTGAC ACGATGTGCC CGGGACAGGA AGCAGGAAGT 
GCGGAGGAAA AGTCTGCAGA GGAAGTTACC ATGAGCCCAG CCATCACTAT CATGCGGCCC 
ATCCTCAGGT TCCTGCAGTT ACTGTGTGAG AATCACAACC GGGAGCTTCA GAACTTCTTG 
AGGAACCAGA ACAACAAAAC AAACTACAAC CTTGTCTGTG AAACACTTCA GTTTCTGGAC 
TGCATCTGTG GAAGCACCAC AGGGGGCCTA GGCCTGCTGG GGCTCTACAT CAATGAGAAG 
AACGTAGCTC TGGTCAACCA GACCCTGGAG AGCTTGACCG AGTACTGCCA GGGCCCGTGT 
CATGAGAACC AGACCTGTAT CGCCACTCAC GAATCCAATG GGATTGACAT CATCATCGCC 
TTGATTCTGA GTGACATCAA CCCTCTGGGC AAGTACAGAA TGGACCTGGT GCTACAGCTG 
AAGAACAACG CCTCCAAGCT TCTGCTGGCC ATTATGGAGA GCAGACACGA CAGTGAGAAT 
GCAGAGAGAA TTCTCTTCAA CATGAGACCC AAGGAACTGG TGGATGTCAT GAAGAATGCC 
TATAACCAAG GCCTGGAATG TAACCATGGG GACGAGGAGG GAGGAGATGA TGGTGTTTCT 
CCAAAAGACG TTGGACACAA CATCTACATC CTGGCCCATC AGTTGGCCCG CCACAATAAA 
CTCCTACAGC AGATGCTCAA GCCTGGATCC GATCCAGAGG AAGGGGATGA AGCCTTGAAG 
TACTATGCCA ACCACACCGC ACAGATCGAG ATTGTGCGGC ACGACCGGAC TATGGAGCAG 
ATTGTTTTCC CCGTCCCCAA TATCTGCGAA TTCCTCACTC GGGAATCCAA ATACCGGGTG 
TTCAACACAA CGGAGAGGGA TGAGCAAGGA AGCAAGGTGA ACGACTTCTT CCAGCAAACG 
GAAGATCTCT ACAACGAGAT GAAATGGCAA AAGAAGATCA GGAACAACCC CGCCCTGTTC 
TGGTTCTCCA GGCACATCTC CCTGTGGGGG AGCATCTCCT TCAACCTGGC TGTGTTCATC 
AACCTGGCCG TGGCTCTCTT CTACCCATTC GGGGATGACG GCGATGAAGG TACGCTCTCC 
CCGCTGTTCT CAGCCCTCCT TTGGGTAGCA GTGGCGATCT GCACGTCTAT GCTGTTCTTC 
TTCTCCAAGC CTGTGGGCAT CCGGCCATTC CTTGTGTCTA TCATGCTCAG ATCAATATAC 
ACCATCGGTC TGGGGCCAAC GCTAATACTT CTTGGTGCTG CCAATCTATG CAATAAAATC 
GTGTTCCTGG TGAGTTTTGT GGGAAACCGA GGCACATTCA CCCGAGGGTA CCGAGCAGTC 
ATTCTGGACA TGGCCTTTCT TTACCACGTG GCCTATGTCT TGGTTTGCAT GCTTGGCCTC 
TTCGTCCACG AGTTCTTCTA CAGCTTCCTG CTTTTTGACT TGGTGTACAG AGAAGAGACC 
CTGCTGAACG TCATCAAAAG CGTCACACGG AATGGCCGCT CCATCATCCT GACTGCGGTC 
TTGGCTCTTA TCCTGGTCTA CCTGTTCTCC ATCATCGGCT TCCTTTTCTT AAAGGATGAC 
TTCACCATGG AGGTGGACAG ATTGAAAAAC AGAACTCCAG TCACAGGTAA CGACGGGGTT 
CCCACTATGA CCTTAACTTC CATGCTGGGA ACCTGCCCTA AGGAAAACTG CTCACCCACG 
ATCCCCTCTT CGAATGCAGC CGGTGAGGGA GGTGAGGACG GCATCGAGAG GACCTGTGAC 
ACCCTGCTCA TGTGCATTGT CACCGTGCTG AACCAGGGCC TCAGGAATGG TGGCGGAGTT 
GGTGACGTGC TGAGACGACC CTCGAAGGAT GAGCCTTTGT TTGCTGCCCG GGTGGTCTAC 
GACCTCCTTT TCTTCTTCAT CGTCATCATC ATCGTCCTTA ACCTGATTTT TGGTGTAATC 
ATTGACACTT TCGCTGACCT CAGGAGTGAG AAGCAGAAGA AAGAAAAAAT TCTCAAGACA 
ACCTGCTTCA TCTGTGGCTT GGAGAGGGAC AAGTTTGATA ACAAGACGGT GTCCTTTGAG 
GAGCACATCA AGTCAGAGCA CAACATGTGG CATTACTTGT ACTTCATCGT CCTGGTGAAG 
GTGAAGGACC CAACAGAATA CACAGGGCCT GAGAGCTACG TGGCTCAGAT GATCACAGAG 
AAGAATTTAG ACTGGTTTCC TCGGATGCGA GCCATGTCAC TTGTCAGCAA TGAAGGTGAC 
AGTGAGCAAA ATGAGATCCG GAACCTGCAG GAGAAGCTGG AGTCCACTAT GAGTCTGGTG 
AAACAGTTGT CGGGGCAGCT GGCAGAGCTG AAGGAGCAGA TGACAGAACA AAGGAAAAAC 
AAGCAAAGGC TGGGCTTCCT TGGATCAAAC ACACCCCATG AGAACCATCA CATGCCACCG 
CACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Type 2 inositol trisphosphate receptor gene expression in hepatocytes is regulated by cyclic AMP.
Biochemical and biophysical research communications486(3)659-664(2017 05)
Kruglov E,Ananthanarayanan M,Sousa P,Weerachayaphorn J,Guerra MT,Nathanson MH

Calcineurin-NFATc regulates type 2 inositol 1,4,5-trisphosphate receptor (InsP3R2) expression during cardiac remodeling.
The Journal of biological chemistry289(9)6188-98(2014 Feb)
Sankar N,deTombe PP,Mignery GA

The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.
The Journal of biological chemistry288(35)25340-9(2013 Aug)
Schulman JJ,Wright FA,Kaufmann T,Wojcikiewicz RJ

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proceedings of the National Academy of Sciences of the United States of America110(8)E643-52(2013 Feb)
Ghai R,Bugarcic A,Liu H,Norwood SJ,Skeldal S,Coulson EJ,Li SS,Teasdale RD,Collins BM

Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy.
The Journal of cell biology199(5)783-98(2012 Nov)
Drawnel FM,Wachten D,Molkentin JD,Maillet M,Aronsen JM,Swift F,Sjaastad I,Liu N,Catalucci D,Mikoshiba K,Hisatsune C,Okkenhaug H,Andrews SR,Bootman MD,Roderick HL

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Itpr2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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