Gng2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gng2
Entrez Gene ID	80850
Full Name	G protein subunit gamma 2
General protein information	Preferred Names G protein subunit gamma 2 Names guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 guanine nucleotide binding protein (G protein), gamma 2 subunit
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p16
Summary	gamma 2 subunit of heterotrimeric G-proteins, which exchange GDP for GTP and activate downstream effectors [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031754.1	NP_113942.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
NM_001257349.1	NP_001244278.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

Pathways from BioSystems

Homologies

Homo sapiens (human)	GNG2	NP_001230702.1
Pan troglodytes (chimpanzee)	GNG2	XP_003314372.1
Bos taurus (cattle)	GNG2	NP_776497.1
Mus musculus (house mouse)	Gng2	NP_001033726.1
Gallus gallus (chicken)	GNG2	NP_001090997.1
Danio rerio (zebrafish)	gng2	NP_001037783.1
Danio rerio (zebrafish)	LOC100332296	XP_002664187.1
	GNG2	XP_002805094.1
Canis lupus familiaris (dog)	GNG2	XP_005623455.1
Xenopus tropicalis (tropical clawed frog)	gng2	NP_001005038.1
Rattus norvegicus (Norway rat)	Gng2	NP_113942.1

Gene Ontology
Bibliography

Related articles in PubMed

G?? and the C terminus of SNAP-25 are necessary for long-term depression of transmitter release.
Zhang XL, Upreti C, Stanton PK
PloS one6(5)e20500(2011)

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)

Proteomic analysis illuminates a novel structural definition of the claustrum and insula.
Mathur BN, Caprioli RM, Deutch AY
Cerebral cortex (New York, N.Y. : 1991)19(10)2372-9(2009 Oct)

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway.
Weissman JT, Ma JN, Essex A, Gao Y, Burstein ES
Oncogene23(1)241-9(2004 Jan)

Direct interactions between the heterotrimeric G protein subunit G beta 5 and the G protein gamma subunit-like domain-containing regulator of G protein signaling 11: gain of function of cyan fluorescent protein-tagged G gamma 3.
Zhou JY, Toth PT, Miller RJ
The Journal of pharmacology and experimental therapeutics305(2)460-6(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that the C-terminus of SNAP-25 is a binding target for Gbetagamma necessary for both transient transmitter-mediated presynaptic inhibition, and the induction of presynaptic LTD.
Title: G?? and the C terminus of SNAP-25 are necessary for long-term depression of transmitter release.

We used matrix-assisted laser desorption ionization-imaging mass spectrometry to reveal a novel protein marker, G-protein gamma2 subunit (Gng2), which is enriched in the claustrum but not adjacent structures of the rat forebrain.
Title: Proteomic analysis illuminates a novel structural definition of the claustrum and insula.

The following Gng2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gng2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08659	NM_031754.1 Latest version!	Rattus norvegicus G protein subunit gamma 2 (Gng2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa08659	NM_001257349.1 Latest version!	Rattus norvegicus G protein subunit gamma 2 (Gng2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gng2 ( NM_031754.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113942.1 Rattus norvegicus G protein subunit gamma 2 (Gng2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa08659
Clone ID Related Accession (Same CDS sequence)	NM_031754.1 , NM_001257349.1
Accession Version	NM_031754.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-30
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB609817.1 and AAHX01081981.1. On or before Apr 1, 2012 this sequence version replaced XM_002725028.1, XM_002725029.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CB609817.1, FQ214279.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCAGCA ACAACACCGC CAGCATAGCG CAAGCCAGGA AACTGGTCGA GCAGCTGAAG 
ATGGAAGCCA GCATCGACAG GATAAAGGTG TCCAAGGCAG CTGCAGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGATCCCCTG CTGACCCCAG TCCCGGCCTC AGAAAATCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113942.1
CDS	170..385
Translation	MASNNTASIAQARKLVEQLKMEASIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	NM_031754.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit gamma 2 (Gng2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031754.1

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCG CAAGCCAGGA AACTGGTCGA GCAGCTGAAG 
ATGGAAGCCA GCATCGACAG GATAAAGGTG TCCAAGGCAG CTGCAGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGATCCCCTG CTGACCCCAG TCCCGGCCTC AGAAAATCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gng2 ( NM_001257349.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001244278.1 Rattus norvegicus G protein subunit gamma 2 (Gng2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa08659
Clone ID Related Accession (Same CDS sequence)	NM_031754.1 , NM_001257349.1
Accession Version	NM_001257349.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-30
Organism	Rattus norvegicus(Norway rat)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FM112505.1 and AAHX01081981.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: FM112505.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCAGCA ACAACACCGC CAGCATAGCG CAAGCCAGGA AACTGGTCGA GCAGCTGAAG 
ATGGAAGCCA GCATCGACAG GATAAAGGTG TCCAAGGCAG CTGCAGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGATCCCCTG CTGACCCCAG TCCCGGCCTC AGAAAATCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001244278.1
CDS	153..368
Translation	MASNNTASIAQARKLVEQLKMEASIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	NM_001257349.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus G protein subunit gamma 2 (Gng2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001257349.1

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCG CAAGCCAGGA AACTGGTCGA GCAGCTGAAG 
ATGGAAGCCA GCATCGACAG GATAAAGGTG TCCAAGGCAG CTGCAGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGATCCCCTG CTGACCCCAG TCCCGGCCTC AGAAAATCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

G?? and the C terminus of SNAP-25 are necessary for long-term depression of transmitter release.
PloS one6(5)e20500(2011)
Zhang XL,Upreti C,Stanton PK

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Buschow SI,van Balkom BW,Aalberts M,Heck AJ,Wauben M,Stoorvogel W

Proteomic analysis illuminates a novel structural definition of the claustrum and insula.
Cerebral cortex (New York, N.Y. : 1991)19(10)2372-9(2009 Oct)
Mathur BN,Caprioli RM,Deutch AY

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway.
Oncogene23(1)241-9(2004 Jan)
Weissman JT,Ma JN,Essex A,Gao Y,Burstein ES

Direct interactions between the heterotrimeric G protein subunit G beta 5 and the G protein gamma subunit-like domain-containing regulator of G protein signaling 11: gain of function of cyan fluorescent protein-tagged G gamma 3.
The Journal of pharmacology and experimental therapeutics305(2)460-6(2003 May)
Zhou JY,Toth PT,Miller RJ

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Gng2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報