Gng2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Gng2
Entrez Gene ID	14702
Full Name	guanine nucleotide binding protein (G protein), gamma 2
General protein information	Preferred Names guanine nucleotide binding protein (G protein), gamma 2 Names guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 g gamma-I
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14 A3\|14 11.17 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_030247652.1	XP_030103512.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 isoform X1
NM_001285910.1	NP_001272839.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001285909.1	NP_001272838.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001285908.1	NP_001272837.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001285911.1	NP_001272840.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_010315.4	NP_034445.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
NM_001038637.1	NP_001033726.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	GNG2	NP_001230702.1
Pan troglodytes (chimpanzee)	GNG2	XP_003314372.1
Bos taurus (cattle)	GNG2	NP_776497.1
Mus musculus (house mouse)	Gng2	NP_001033726.1
Gallus gallus (chicken)	GNG2	NP_001090997.1
Danio rerio (zebrafish)	gng2	NP_001037783.1
Danio rerio (zebrafish)	LOC100332296	XP_002664187.1
	GNG2	XP_002805094.1
Canis lupus familiaris (dog)	GNG2	XP_005623455.1
Xenopus tropicalis (tropical clawed frog)	gng2	NP_001005038.1
Rattus norvegicus (Norway rat)	Gng2	NP_113942.1

Gene Ontology
Bibliography

Related articles in PubMed

Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels.
Wang W, Touhara KK, Weir K, Bean BP, MacKinnon R
eLife5(2016 04)

Aggressive behaviour and physiological responses to pheromones are strongly impaired in mice deficient for the olfactory G-protein -subunit G8.
Montani G, Tonelli S, Sanghez V, Ferrari PF, Palanza P, Zimmer A, Tirindelli R
The Journal of physiology591(16)3949-62(2013 Aug)

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH
PloS one6(2)e17286(2011 Feb)

Genetic variations strongly influence phenotypic outcome in the mouse retina.
Jelcick AS, Yuan Y, Leehy BD, Cox LC, Silveira AC, Qiu F, Schenk S, Sachs AJ, Morrison MA, Nystuen AM, DeAngelis MM, Haider NB
PloS one6(7)e21858(2011)

In vivo expression of G-protein beta1gamma2 dimer in adult mouse skeletal muscle alters L-type calcium current and excitation-contraction coupling.
Weiss N, Legrand C, Pouvreau S, Bichraoui H, Allard B, Zamponi GW, De Waard M, Jacquemond V
The Journal of physiology588(Pt 15)2945-60(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

It was concluded that GIRK2, through its dual responsiveness to G protein beta-gamma and Na+, mediates a form of neuronal inhibition that is amplifiable in the setting of excess electrical activity.
Title: Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels.

signaling pathway by which G(i)-coupled receptor specifically induces Rac and Cdc42 activation through direct interaction of Gbetagamma with FLJ00018.
Title: Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42.

The following Gng2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gng2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu00257	NM_001285911.1 Latest version!	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu00257	NM_001038637.1 Latest version!	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu00257	NM_001285910.1 Latest version!	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu00257	NM_001285909.1 Latest version!	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu00257	NM_010315.4 Latest version!	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu00257	NM_001285908.1 Latest version!	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu00257	XM_030247652.1 Latest version!	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Gng2 ( NM_001285910.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001272839.1 Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OMu00257
Clone ID Related Accession (Same CDS sequence)	XM_030247652.1 , NM_001285910.1 , NM_001285909.1 , NM_001285908.1 , NM_001285911.1 , NM_010315.4 , NM_001038637.1
Accession Version	NM_001285910.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK158697.1, BY108799.1 and AC130831.4. Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BY249036.1, BY109868.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001272839.1
CDS	322..537
Translation	MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	NM_001285910.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001285910.1

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gng2 ( NM_001285909.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001272838.1 Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OMu00257
Clone ID Related Accession (Same CDS sequence)	XM_030247652.1 , NM_001285910.1 , NM_001285909.1 , NM_001285908.1 , NM_001285911.1 , NM_010315.4 , NM_001038637.1
Accession Version	NM_001285909.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY245532.1, CA324196.1 and AC130831.4. Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CA324196.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001272838.1
CDS	282..497
Translation	MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	NM_001285909.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001285909.1

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gng2 ( NM_001285908.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001272837.1 Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OMu00257
Clone ID Related Accession (Same CDS sequence)	XM_030247652.1 , NM_001285910.1 , NM_001285909.1 , NM_001285908.1 , NM_001285911.1 , NM_010315.4 , NM_001038637.1
Accession Version	NM_001285908.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY245532.1, W48309.1 and AC130831.4. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.168089.1, W48309.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001272837.1
CDS	175..390
Translation	MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	NM_001285908.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001285908.1

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gng2 ( NM_001285911.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001272840.1 Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OMu00257
Clone ID Related Accession (Same CDS sequence)	XM_030247652.1 , NM_001285910.1 , NM_001285909.1 , NM_001285908.1 , NM_001285911.1 , NM_010315.4 , NM_001038637.1
Accession Version	NM_001285911.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC130831.4 and W48309.1. Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CJ171514.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001272840.1
CDS	190..405
Translation	MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	NM_001285911.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001285911.1

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gng2 ( NM_010315.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034445.1 Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu00257
Clone ID Related Accession (Same CDS sequence)	XM_030247652.1 , NM_001285910.1 , NM_001285909.1 , NM_001285908.1 , NM_001285911.1 , NM_010315.4 , NM_001038637.1
Accession Version	NM_010315.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY245532.1, AK158697.1, AK160396.1 and AC130831.4. On Jan 6, 2006 this sequence version replaced NM_010315.3. Transcript Variant: This variant (1) represents the longest transcript. Variants 1-6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK158697.1, SRR1660817.116339.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034445.1
CDS	363..578
Translation	MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	NM_010315.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010315.4

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gng2 ( NM_001038637.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001033726.1 Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu00257
Clone ID Related Accession (Same CDS sequence)	XM_030247652.1 , NM_001285910.1 , NM_001285909.1 , NM_001285908.1 , NM_001285911.1 , NM_010315.4 , NM_001038637.1
Accession Version	NM_001038637.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY245532.1, AK158697.1, AK160396.1 and AC130831.4. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-6 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.32614.1, BY241310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164138 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001033726.1
CDS	215..430
Translation	MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	NM_001038637.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001038637.1

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gng2 ( XM_030247652.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030103512.1 Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant X1, mRNA.

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CloneID	OMu00257
Clone ID Related Accession (Same CDS sequence)	XM_030247652.1 , NM_001285910.1 , NM_001285909.1 , NM_001285908.1 , NM_001285911.1 , NM_010315.4 , NM_001038637.1
Accession Version	XM_030247652.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 216bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030103512.1
CDS	151..366
Translation	MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL

Target ORF information:

RefSeq Version	XM_030247652.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus guanine nucleotide binding protein (G protein), gamma 2 (Gng2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030247652.1

ORF Insert Sequence:

ATGGCCAGCA ACAACACCGC CAGCATAGCA CAAGCCAGGA AGCTGGTAGA ACAGCTGAAG 
ATGGAAGCCA ACATCGACAG GATAAAGGTG TCCAAGGCAG CTGCTGACTT GATGGCCTAC 
TGTGAGGCAC ATGCCAAGGA AGACCCTCTG CTGACCCCAG TCCCAGCCTC AGAAAACCCC 
TTTCGGGAGA AGAAGTTCTT CTGCGCCATC CTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels.
eLife5(2016 04)
Wang W,Touhara KK,Weir K,Bean BP,MacKinnon R

Aggressive behaviour and physiological responses to pheromones are strongly impaired in mice deficient for the olfactory G-protein -subunit G8.
The Journal of physiology591(16)3949-62(2013 Aug)
Montani G,Tonelli S,Sanghez V,Ferrari PF,Palanza P,Zimmer A,Tirindelli R

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
PloS one6(2)e17286(2011 Feb)
Thiagarajan RD,Georgas KM,Rumballe BA,Lesieur E,Chiu HS,Taylor D,Tang DT,Grimmond SM,Little MH

Genetic variations strongly influence phenotypic outcome in the mouse retina.
PloS one6(7)e21858(2011)
Jelcick AS,Yuan Y,Leehy BD,Cox LC,Silveira AC,Qiu F,Schenk S,Sachs AJ,Morrison MA,Nystuen AM,DeAngelis MM,Haider NB

In vivo expression of G-protein beta1gamma2 dimer in adult mouse skeletal muscle alters L-type calcium current and excitation-contraction coupling.
The Journal of physiology588(Pt 15)2945-60(2010 Aug)
Weiss N,Legrand C,Pouvreau S,Bichraoui H,Allard B,Zamponi GW,De Waard M,Jacquemond V

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Gng2 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

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Target ORF information:

ORF Insert Sequence:

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