Mapk11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mapk11
Entrez Gene ID	689314
Full Name	mitogen-activated protein kinase 11
Synonyms	p38beta
General protein information	Preferred Names mitogen-activated protein kinase 11 Names mitogen-activated protein kinase 11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q34

mRNA and Protein(s)

mRNA	Protein	Name
XM_017595119.1	XP_017450608.1	mitogen-activated protein kinase 11 isoform X1
XM_017595120.1	XP_017450609.1	mitogen-activated protein kinase 11 isoform X2
NM_001109532.2	NP_001103002.2	mitogen-activated protein kinase 11

Pathways from BioSystems

Homologies

	MAPK11	XP_001112524.1
Mus musculus (house mouse)	Mapk11	NP_035291.4
Homo sapiens (human)	MAPK11	NP_002742.3
Xenopus tropicalis (tropical clawed frog)	mapk11	NP_001098754.1
Arabidopsis thaliana (thale cress)	MPK10	NP_191538.1
Bos taurus (cattle)	MAPK11	NP_001073804.1
Rattus norvegicus (Norway rat)	Mapk11	NP_001103002.2
Gallus gallus (chicken)	MAPK11	NP_001006227.1
Canis lupus familiaris (dog)	MAPK11	XP_005625768.1
Danio rerio (zebrafish)	mapk11	NP_001002095.1

Gene Ontology
Bibliography

Related articles in PubMed

Up-regulation of galectin-9 induces cell migration in human dendritic cells infected with dengue virus.
Hsu YL, Wang MY, Ho LJ, Huang CY, Lai JH
Journal of cellular and molecular medicine19(5)1065-76(2015 May)

Mitochondrial p38? and manganese superoxide dismutase interaction mediated by estrogen in cardiomyocytes.
Liu H, Yanamandala M, Lee TC, Kim JK
PloS one9(1)e85272(2014)

Protein arginine methyltransferase 1 interacts with and activates p38? to facilitate erythroid differentiation.
Hua WK, Chang YI, Yao CL, Hwang SM, Chang CY, Lin WJ
PloS one8(3)e56715(2013)

Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells.
Kogai T, Liu YY, Mody K, Shamsian DV, Brent GA
The Journal of biological chemistry287(5)3292-300(2012 Jan)

p38? MAPK affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of ?B-crystallin and its anti-apoptotic function.
Shin JH, Jeong JY, Jin Y, Kim ID, Lee JK
Neuroscience letters501(3)132-7(2011 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate a functionally active mitochondrial pool of p38beta mitogen activated protein kinase (p38beta MAPK), and that this kinase phosphorylates manganese superoxide dismutase (MnSOD) in an 17beta-estradiol (E2)-dependent manner.
Title: Mitochondrial p38? and manganese superoxide dismutase interaction mediated by estrogen in cardiomyocytes.

Overexpression of p38beta or Rac1 significantly enhanced (1.9- and 3.9-fold, respectively), the tRA-stimulated NIS expression in MCF-7 cells.
Title: Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells.

p38beta confers protection against hydrogen peroxide (HO)-induced astrocyte apoptosis by inducing a small heat shock protein, alphaB-crystallin, which inhibits caspase-3 activation.
Title: p38? MAPK affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of ?B-crystallin and its anti-apoptotic function.

p38beta-induced B-natriuretic peptide transcription was mediated by a GATA-4 transcription factor binding site.
Title: Distinct regulation of B-type natriuretic peptide transcription by p38 MAPK isoforms.

Data shwo that hyperalgesia is prevented by downregulation of p38beta but not p38alpha, whereas increases in spinal COX-2 protein expression at 8 hours are mediated by both p38alpha and beta isoforms.
Title: Role of spinal p38alpha and beta MAPK in inflammatory hyperalgesia and spinal COX-2 expression.

The following Mapk11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mapk11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10231	NM_001109532.2 Latest version!	Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa62160	XM_017595119.1 Latest version!	Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa62161	XM_017595120.1 Latest version!	Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mapk11 ( NM_001109532.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001103002.2 Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), mRNA.

Price & Availability↑

CloneID	ORa10231
Clone ID Related Accession (Same CDS sequence)	NM_001109532.2
Accession Version	NM_001109532.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	mitogen-activated protein kinase 11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474027.1. On Sep 13, 2008 this sequence version replaced NM_001109532.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCGGGTC CGCGCGCGGG ATTCTACCGG CAAGAGCTGA ACAAAACAGT ATGGGAGGTG 
CCGCAGCGGC TGCAGGGCCT ACGCCCGGTG GGCTCCGGCG CCTACGGCTC GGTCTGTTCG 
GCCTACGACG CACGGCTGCG CCAGAAGGTG GCTGTGAAGA AGCTGTCTCG CCCTTTCCAA 
TCGCTGATCC ACGCGAGGAG GACATACCGT GAGCTACGCC TACTCAAACA CCTGAAGCAC 
GAGAACGTCA TAGGACTTTT GGACGTCTTC ACGCCGGCCA CATCCATCGA GGATTTCAGC 
GAAGTGTACC TCGTGACCAC CCTGATGGGC GCTGACCTGA ATAACATCGT CAAGTGTCAG 
GCCCTGAGCG ATGAGCATGT TCAGTTCCTT GTCTACCAGC TGCTGCGTGG GCTGAAGTAT 
ATCCACTCGG CGGGCATCAT CCACCGGGAC CTGAAGCCCA GCAATGTAGC AGTGAATGAG 
GACTGCGAGC TGAGGATCCT GGACTTTGGG CTGGCACGCC AGGCTGATGA GGAGATGACT 
GGATATGTGG CCACACGGTG GTACCGGGCT CCAGAGATCA TGCTGAACTG GATGCACTAC 
AACCAGACAG TGGACATCTG GTCTGTGGGC TGCATCATGG CTGAGCTGCT CCAAGGAAAG 
GCCCTCTTTC CTGGAAATGA CTACATCGAC CAGCTGAAGC GGATCATGGA GGTGGTGGGC 
ACACCCAGCC CTGAGGTTCT GGCAAAGATA TCCTCGGAGC ATGCCCGGAC ATACATCCAG 
TCTCTGCCTC CCATGCCCCA GAAGGACCTC AGCAGTGTCT TCCATGGGGC CAACCCTCTG 
GCTGTAGACC TCCTTGGAAG AATGCTGGTG CTAGACAGTG ACCAGAGAGT CAGTGCGGCC 
GAAGCCTTGG CCCATGCATA CTTCAGCCAG TACCATGACC CTGACGACGA GCCAGAGGCC 
GAGCCCTATG ATGAAAGTGT TGAGGCCAAG GAGCGCACCC TGGAGGAGTG GAAGGAGCTT 
ACTTACCAGG AAGTCCTTAG CTTCAAGCCC CTGGAAACAT CGCAGCTCCC TGGCACCCAT 
GAAATTGAGC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001103002.2
CDS	72..1166
Translation	MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPLETSQLPGTHEIEQ

Target ORF information:

RefSeq Version	NM_001109532.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109532.2

ORF Insert Sequence:

ATGTCGGGTC CGCGCGCGGG ATTCTACCGG CAAGAGCTGA ACAAAACAGT ATGGGAGGTG 
CCGCAGCGGC TGCAGGGCCT ACGCCCGGTG GGCTCCGGCG CCTACGGCTC GGTCTGTTCG 
GCCTACGACG CACGGCTGCG CCAGAAGGTG GCTGTGAAGA AGCTGTCTCG CCCTTTCCAA 
TCGCTGATCC ACGCGAGGAG GACATACCGT GAGCTACGCC TACTCAAACA CCTGAAGCAC 
GAGAACGTCA TAGGACTTTT GGACGTCTTC ACGCCGGCCA CATCCATCGA GGATTTCAGC 
GAAGTGTACC TCGTGACCAC CCTGATGGGC GCTGACCTGA ATAACATCGT CAAGTGTCAG 
GCCCTGAGCG ATGAGCATGT TCAGTTCCTT GTCTACCAGC TGCTGCGTGG GCTGAAGTAT 
ATCCACTCGG CGGGCATCAT CCACCGGGAC CTGAAGCCCA GCAATGTAGC AGTGAATGAG 
GACTGCGAGC TGAGGATCCT GGACTTTGGG CTGGCACGCC AGGCTGATGA GGAGATGACT 
GGATATGTGG CCACACGGTG GTACCGGGCT CCAGAGATCA TGCTGAACTG GATGCACTAC 
AACCAGACAG TGGACATCTG GTCTGTGGGC TGCATCATGG CTGAGCTGCT CCAAGGAAAG 
GCCCTCTTTC CTGGAAATGA CTACATCGAC CAGCTGAAGC GGATCATGGA GGTGGTGGGC 
ACACCCAGCC CTGAGGTTCT GGCAAAGATA TCCTCGGAGC ATGCCCGGAC ATACATCCAG 
TCTCTGCCTC CCATGCCCCA GAAGGACCTC AGCAGTGTCT TCCATGGGGC CAACCCTCTG 
GCTGTAGACC TCCTTGGAAG AATGCTGGTG CTAGACAGTG ACCAGAGAGT CAGTGCGGCC 
GAAGCCTTGG CCCATGCATA CTTCAGCCAG TACCATGACC CTGACGACGA GCCAGAGGCC 
GAGCCCTATG ATGAAAGTGT TGAGGCCAAG GAGCGCACCC TGGAGGAGTG GAAGGAGCTT 
ACTTACCAGG AAGTCCTTAG CTTCAAGCCC CTGGAAACAT CGCAGCTCCC TGGCACCCAT 
GAAATTGAGC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mapk11 ( XM_017595119.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450608.1 Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62160
Clone ID Related Accession (Same CDS sequence)	XM_017595119.1
Accession Version	XM_017595119.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	mitogen-activated protein kinase 11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGGGTC CGCGCGCGGG ATTCTACCGG CAAGAGCTGA ACAAAACAGT ATGGGAGGTG 
CCGCAGCGGC TGCAGGGCCT ACGCCCGGTG GGCTCCGGCG CCTACGGCTC GGTCTGGTCG 
CACCCAGGCC CTCCACATTC GGCCTACGAC GCACGGCTGC GCCAGAAGGT GGCTGTGAAG 
AAGCTGTCTC GCCCTTTCCA ATCGCTGATC CACGCGAGGA GGACATACCG TGAGCTACGC 
CTACTCAAAC ACCTGAAGCA CGAGAACGTC ATAGGACTTT TGGACGTCTT CACGCCGGCC 
ACATCCATCG AGGATTTCAG CGAAGTGTAC CTCGTGACCA CCCTGATGGG CGCTGACCTG 
AATAACATCG TCAAGTGTCA GGCCCTGAGC GATGAGCATG TTCAGTTCCT TGTCTACCAG 
CTGCTGCGTG GGCTGAAGTA TATCCACTCG GCGGGCATCA TCCACCGGGA CCTGAAGCCC 
AGCAATGTAG CAGTGAATGA GGACTGCGAG CTGAGGATCC TGGACTTTGG GCTGGCACGC 
CAGGCTGATG AGGAGATGAC TGGATATGTG GCCACACGGT GGTACCGGGC TCCAGAGATC 
ATGCTGAACT GGATGCACTA CAACCAGACA GTGGACATCT GGTCTGTGGG CTGCATCATG 
GCTGAGCTGC TCCAAGGAAA GGCCCTCTTT CCTGGAAATG ACTACATCGA CCAGCTGAAG 
CGGATCATGG AGGTGGTGGG CACACCCAGC CCTGAGGTTC TGGCAAAGAT ATCCTCGGAG 
CATGCCCGGA CATACATCCA GTCTCTGCCT CCCATGCCCC AGAAGGACCT CAGCAGTGTC 
TTCCATGGGG CCAACCCTCT GGCTGTAGAC CTCCTTGGAA GAATGCTGGT GCTAGACAGT 
GACCAGAGAG TCAGTGCGGC CGAAGCCTTG GCCCATGCAT ACTTCAGCCA GTACCATGAC 
CCTGACGACG AGCCAGAGGC CGAGCCCTAT GATGAAAGTG TTGAGGCCAA GGAGCGCACC 
CTGGAGGAGT GGAAGGAGCT TACTTACCAG GAAGTCCTTA GCTTCAAGCC CCTGGAAACA 
TCGCAGCTCC CTGGCACCCA TGAAATTGAG CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450608.1
CDS	124..1239
Translation	MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVWSHPGPPHSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPLETSQLPGTHEIEQ

Target ORF information:

RefSeq Version	XM_017595119.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017595119.1

ORF Insert Sequence:

ATGTCGGGTC CGCGCGCGGG ATTCTACCGG CAAGAGCTGA ACAAAACAGT ATGGGAGGTG 
CCGCAGCGGC TGCAGGGCCT ACGCCCGGTG GGCTCCGGCG CCTACGGCTC GGTCTGGTCG 
CACCCAGGCC CTCCACATTC GGCCTACGAC GCACGGCTGC GCCAGAAGGT GGCTGTGAAG 
AAGCTGTCTC GCCCTTTCCA ATCGCTGATC CACGCGAGGA GGACATACCG TGAGCTACGC 
CTACTCAAAC ACCTGAAGCA CGAGAACGTC ATAGGACTTT TGGACGTCTT CACGCCGGCC 
ACATCCATCG AGGATTTCAG CGAAGTGTAC CTCGTGACCA CCCTGATGGG CGCTGACCTG 
AATAACATCG TCAAGTGTCA GGCCCTGAGC GATGAGCATG TTCAGTTCCT TGTCTACCAG 
CTGCTGCGTG GGCTGAAGTA TATCCACTCG GCGGGCATCA TCCACCGGGA CCTGAAGCCC 
AGCAATGTAG CAGTGAATGA GGACTGCGAG CTGAGGATCC TGGACTTTGG GCTGGCACGC 
CAGGCTGATG AGGAGATGAC TGGATATGTG GCCACACGGT GGTACCGGGC TCCAGAGATC 
ATGCTGAACT GGATGCACTA CAACCAGACA GTGGACATCT GGTCTGTGGG CTGCATCATG 
GCTGAGCTGC TCCAAGGAAA GGCCCTCTTT CCTGGAAATG ACTACATCGA CCAGCTGAAG 
CGGATCATGG AGGTGGTGGG CACACCCAGC CCTGAGGTTC TGGCAAAGAT ATCCTCGGAG 
CATGCCCGGA CATACATCCA GTCTCTGCCT CCCATGCCCC AGAAGGACCT CAGCAGTGTC 
TTCCATGGGG CCAACCCTCT GGCTGTAGAC CTCCTTGGAA GAATGCTGGT GCTAGACAGT 
GACCAGAGAG TCAGTGCGGC CGAAGCCTTG GCCCATGCAT ACTTCAGCCA GTACCATGAC 
CCTGACGACG AGCCAGAGGC CGAGCCCTAT GATGAAAGTG TTGAGGCCAA GGAGCGCACC 
CTGGAGGAGT GGAAGGAGCT TACTTACCAG GAAGTCCTTA GCTTCAAGCC CCTGGAAACA 
TCGCAGCTCC CTGGCACCCA TGAAATTGAG CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mapk11 ( XM_017595120.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450609.1 Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa62161
Clone ID Related Accession (Same CDS sequence)	XM_017595120.1
Accession Version	XM_017595120.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	mitogen-activated protein kinase 11 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGTCTT GTCTCCTGAA GGCCGGTCAT TTACTAAGAC ATTCGGCCTA CGACGCACGG 
CTGCGCCAGA AGGTGGCTGT GAAGAAGCTG TCTCGCCCTT TCCAATCGCT GATCCACGCG 
AGGAGGACAT ACCGTGAGCT ACGCCTACTC AAACACCTGA AGCACGAGAA CGTCATAGGA 
CTTTTGGACG TCTTCACGCC GGCCACATCC ATCGAGGATT TCAGCGAAGT GTACCTCGTG 
ACCACCCTGA TGGGCGCTGA CCTGAATAAC ATCGTCAAGT GTCAGGCCCT GAGCGATGAG 
CATGTTCAGT TCCTTGTCTA CCAGCTGCTG CGTGGGCTGA AGTATATCCA CTCGGCGGGC 
ATCATCCACC GGGACCTGAA GCCCAGCAAT GTAGCAGTGA ATGAGGACTG CGAGCTGAGG 
ATCCTGGACT TTGGGCTGGC ACGCCAGGCT GATGAGGAGA TGACTGGATA TGTGGCCACA 
CGGTGGTACC GGGCTCCAGA GATCATGCTG AACTGGATGC ACTACAACCA GACAGTGGAC 
ATCTGGTCTG TGGGCTGCAT CATGGCTGAG CTGCTCCAAG GAAAGGCCCT CTTTCCTGGA 
AATGACTACA TCGACCAGCT GAAGCGGATC ATGGAGGTGG TGGGCACACC CAGCCCTGAG 
GTTCTGGCAA AGATATCCTC GGAGCATGCC CGGACATACA TCCAGTCTCT GCCTCCCATG 
CCCCAGAAGG ACCTCAGCAG TGTCTTCCAT GGGGCCAACC CTCTGGCTGT AGACCTCCTT 
GGAAGAATGC TGGTGCTAGA CAGTGACCAG AGAGTCAGTG CGGCCGAAGC CTTGGCCCAT 
GCATACTTCA GCCAGTACCA TGACCCTGAC GACGAGCCAG AGGCCGAGCC CTATGATGAA 
AGTGTTGAGG CCAAGGAGCG CACCCTGGAG GAGTGGAAGG AGCTTACTTA CCAGGAAGTC 
CTTAGCTTCA AGCCCCTGGA AACATCGCAG CTCCCTGGCA CCCATGAAAT TGAGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450609.1
CDS	26..1045
Translation	MSSCLLKAGHLLRHSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSVFHGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPLETSQLPGTHEIEQ

Target ORF information:

RefSeq Version	XM_017595120.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus mitogen-activated protein kinase 11 (Mapk11), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017595120.1

ORF Insert Sequence:

ATGTCGTCTT GTCTCCTGAA GGCCGGTCAT TTACTAAGAC ATTCGGCCTA CGACGCACGG 
CTGCGCCAGA AGGTGGCTGT GAAGAAGCTG TCTCGCCCTT TCCAATCGCT GATCCACGCG 
AGGAGGACAT ACCGTGAGCT ACGCCTACTC AAACACCTGA AGCACGAGAA CGTCATAGGA 
CTTTTGGACG TCTTCACGCC GGCCACATCC ATCGAGGATT TCAGCGAAGT GTACCTCGTG 
ACCACCCTGA TGGGCGCTGA CCTGAATAAC ATCGTCAAGT GTCAGGCCCT GAGCGATGAG 
CATGTTCAGT TCCTTGTCTA CCAGCTGCTG CGTGGGCTGA AGTATATCCA CTCGGCGGGC 
ATCATCCACC GGGACCTGAA GCCCAGCAAT GTAGCAGTGA ATGAGGACTG CGAGCTGAGG 
ATCCTGGACT TTGGGCTGGC ACGCCAGGCT GATGAGGAGA TGACTGGATA TGTGGCCACA 
CGGTGGTACC GGGCTCCAGA GATCATGCTG AACTGGATGC ACTACAACCA GACAGTGGAC 
ATCTGGTCTG TGGGCTGCAT CATGGCTGAG CTGCTCCAAG GAAAGGCCCT CTTTCCTGGA 
AATGACTACA TCGACCAGCT GAAGCGGATC ATGGAGGTGG TGGGCACACC CAGCCCTGAG 
GTTCTGGCAA AGATATCCTC GGAGCATGCC CGGACATACA TCCAGTCTCT GCCTCCCATG 
CCCCAGAAGG ACCTCAGCAG TGTCTTCCAT GGGGCCAACC CTCTGGCTGT AGACCTCCTT 
GGAAGAATGC TGGTGCTAGA CAGTGACCAG AGAGTCAGTG CGGCCGAAGC CTTGGCCCAT 
GCATACTTCA GCCAGTACCA TGACCCTGAC GACGAGCCAG AGGCCGAGCC CTATGATGAA 
AGTGTTGAGG CCAAGGAGCG CACCCTGGAG GAGTGGAAGG AGCTTACTTA CCAGGAAGTC 
CTTAGCTTCA AGCCCCTGGA AACATCGCAG CTCCCTGGCA CCCATGAAAT TGAGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Up-regulation of galectin-9 induces cell migration in human dendritic cells infected with dengue virus.
Journal of cellular and molecular medicine19(5)1065-76(2015 May)
Hsu YL,Wang MY,Ho LJ,Huang CY,Lai JH

Mitochondrial p38? and manganese superoxide dismutase interaction mediated by estrogen in cardiomyocytes.
PloS one9(1)e85272(2014)
Liu H,Yanamandala M,Lee TC,Kim JK

Protein arginine methyltransferase 1 interacts with and activates p38? to facilitate erythroid differentiation.
PloS one8(3)e56715(2013)
Hua WK,Chang YI,Yao CL,Hwang SM,Chang CY,Lin WJ

Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells.
The Journal of biological chemistry287(5)3292-300(2012 Jan)
Kogai T,Liu YY,Mody K,Shamsian DV,Brent GA

p38? MAPK affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of ?B-crystallin and its anti-apoptotic function.
Neuroscience letters501(3)132-7(2011 Sep)
Shin JH,Jeong JY,Jin Y,Kim ID,Lee JK

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Mapk11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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