Nr1h3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nr1h3
Entrez Gene ID	58852
Full Name	nuclear receptor subfamily 1, group H, member 3
Synonyms	LXRalpha
General protein information	Preferred Names nuclear receptor subfamily 1, group H, member 3 Names oxysterols receptor LXR-alpha RLD-1 liver X receptor alpha nuclear orphan receptor LXR-alpha
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q24
Summary	orphan receptor; involved in the stimulation of CYP7A1 transcription [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006234533.3	XP_006234595.1	oxysterols receptor LXR-alpha isoform X1
XM_006234534.2	XP_006234596.1	oxysterols receptor LXR-alpha isoform X1
XM_006234537.1	XP_006234599.1	oxysterols receptor LXR-alpha isoform X2
XM_006234535.3	XP_006234597.1	oxysterols receptor LXR-alpha isoform X1
NM_031627.2	NP_113815.2	oxysterols receptor LXR-alpha

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Nr1h3	NP_113815.2
Gallus gallus (chicken)	NR1H3	NP_989873.1
Danio rerio (zebrafish)	nr1h3	NP_001017545.1
Homo sapiens (human)	NR1H3	NP_005684.2
Pan troglodytes (chimpanzee)	NR1H3	XP_521906.1
Canis lupus familiaris (dog)	NR1H3	XP_005631319.1
	NR1H3	XP_001109209.1
Bos taurus (cattle)	NR1H3	NP_001014861.1
Mus musculus (house mouse)	Nr1h3	NP_001171201.1

Gene Ontology
Bibliography

Related articles in PubMed

Diosgenin prevents high-fat diet-induced rat non-alcoholic fatty liver disease through the AMPK and LXR signaling pathways.
Cheng S, Liang S, Liu Q, Deng Z, Zhang Y, Du J, Zhang Y, Li S, Cheng B, Ling C
International journal of molecular medicine41(2)1089-1095(2018 Feb)

Insulin induction of SREBP-1c in rodent liver requires LXR?-C/EBP? complex.
Tian J, Goldstein JL, Brown MS
Proceedings of the National Academy of Sciences of the United States of America113(29)8182-7(2016 07)

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.
Hsieh J, Koseki M, Molusky MM, Yakushiji E, Ichi I, Westerterp M, Iqbal J, Chan RB, Abramowicz S, Tascau L, Takiguchi S, Yamashita S, Welch CL, Di Paolo G, Hussain MM, Lefkowitch JH, Rader DJ, Tall AR
Nature535(7611)303-7(2016 07)

Liver X Receptor Agonist TO901317 Prevents Diacylglycerols Accumulation in the Heart of Streptozotocin-Diabetic Rats.
Harasiuk D, Baranowski M, Zabielski P, Chabowski A, G?rski J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology39(1)350-9(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The present study indicates a requirement for C/EBPbeta in the insulin-mediated induction of SREBP-1c mRNA expression in rodent liver. Coupled with previous data showing that this induction requires LXRalpha, our data reported herein indicate a requirement for both transcription factors.
Title: Insulin induction of SREBP-1c in rodent liver requires LXR?-C/EBP? complex.

Data show that TO901317 increased expression of both Liver X receptors (LXRalpha and LXRbeta) isoforms and its target genes: sterol response element binding protein 1c (SREBP-1c) and acetyl-coenzyme A carboxylase 1 (ACC1) in the heart of streptozotocin-diabetes.
Title: Liver X Receptor Agonist TO901317 Prevents Diacylglycerols Accumulation in the Heart of Streptozotocin-Diabetic Rats.

LXRalpha-RNAi treatment significantly downregulated LXRalpha expression and improve steatotic liver graft function and recipient survival after a fatty liver transplantation in rats.
Title: LXRalpha gene downregulation by lentiviral-based RNA interference enhances liver function after fatty liver transplantation in rats.

Data suggest that expression of LXRalpha in liver can be regulated by dietary factors; here, dietary supplementation with 5-caffeoylquinic acid down-regulates expression of LXRalpha and prevents high-fat diet induced obesity.
Title: 5-Caffeoylquinic acid decreases diet-induced obesity in rats by modulating PPAR? and LXR? transcription.

28-Homobrassinolide transactivates LXR genes in the rat tissues.
Title: 28-Homobrassinolide: a novel oxysterol transactivating LXR gene expression.

The following Nr1h3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nr1h3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13593	NM_031627.2 Latest version!	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa13593	XM_006234534.2 Latest version!	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa13593	XM_006234533.3 Latest version!	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa13593	XM_006234535.3 Latest version!	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa26092	XM_006234537.1 Latest version!	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nr1h3 ( NM_031627.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113815.2 Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), mRNA.

Price & Availability↑

CloneID	ORa13593
Clone ID Related Accession (Same CDS sequence)	XM_006234533.3 , XM_006234534.2 , XM_006234535.3 , NM_031627.2
Accession Version	NM_031627.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	oxysterols receptor LXR-alpha
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC088750.1. On Apr 14, 2007 this sequence version replaced NM_031627.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC088750.1, U11685.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGAACT TCGTCCACAG 
AAGCGGAAAA AGGGGCCAGC CCCCAAAATG CTGGGGAACG AGCTATGCAG TGTATGTGGG 
GACAAGGCCT CTGGCTTCCA TTACAATGTG CTGAGCTGCG AGGGCTGCAA GGGATTCTTC 
CGCCGCAGTG TCATCAAGGG AGCACGCTAC ATTTGCCATA GCGGTGGCCA CTGCCCCATG 
GACACCTACA TGCGGCGGAA ATGCCAGGAG TGTCGCCTTC GCAAATGCCG CCAGGCAGGC 
ATGAGGGAGG AGTGTGTCTT ATCAGAAGAA CAGATCCGCT TGAAGAAACT GAAGCGTCAA 
GAAGAGGAGC AGGCTCAAGC CACATCGGTG TCCCCAAGGG TTTCCTCACC GCCCCAGGTC 
CTGCCACAGC TCAGCCCAGA ACAACTGGGC ATGATTGAGA AGTTGGTGGC TGCCCAGCAA 
CAGTGTAACA GGCGCTCCTT CTCTGACCGA CTTCGAGTCA CGCCTTGGCC CATTGCACCC 
GACCCTCAGA GCCGGGAAGC CCGCCAACAG CGCTTTGCCC ACTTTACTGA GCTGGCCATC 
GTGTCCGTGC AGGAGATTGT TGACTTTGCC AAACAGCTCC CTGGCTTCCT ACAGCTGAGC 
AGGGAGGACC AGATCGCCTT GCTGAAGACC TCTGCGATCG AGGTGATGCT TCTGGAGACA 
TCGCGGAGGT ACAACCCTGG GAGTGAGAGC ATCACCTTCC TCAAGGATTT CAGTTACAAC 
CGGGAAGACT TTGCCAAAGC AGGGCTGCAG GTGGAGTTCA TTAACCCCAT CTTTGAGTTC 
TCCAGATCCA TGAATGAACT GCAACTCAAT GATGCTGAAT TTGCTCTGCT CATAGCCATC 
AGCATCTTCT CTGCAGACCG GCCCAACGTG CAGGACCAGC TCCAAGTAGA GAGACTGCAA 
CACACATATG TGGAGGCCCT GCATGCCTAT GTCTCCATCA ACCACCCCCA CGACCGACTG 
ATGTTCCCAC GGATGCTAAT GAAGCTGGTG AGCCTCCGGA CTTTGAGCAG CGTCCATTCA 
GAGCAAGTGT TTGCACTTCG CCTGCAGGAC AAAAAACTTC CCCCTCTGCT CTCCGAGATC 
TGGGATGTCC ACGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113815.2
CDS	18..1355
Translation	MSLWLEAAVPDVSPDSATELWKTEPQDAGDQGGNTCILREEARMPQSTGGALRIGLESSEPTALLPRAETLPEPTELRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGARYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAQATSVSPRVSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRSMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	NM_031627.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031627.2

ORF Insert Sequence:

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGAACT TCGTCCACAG 
AAGCGGAAAA AGGGGCCAGC CCCCAAAATG CTGGGGAACG AGCTATGCAG TGTATGTGGG 
GACAAGGCCT CTGGCTTCCA TTACAATGTG CTGAGCTGCG AGGGCTGCAA GGGATTCTTC 
CGCCGCAGTG TCATCAAGGG AGCACGCTAC ATTTGCCATA GCGGTGGCCA CTGCCCCATG 
GACACCTACA TGCGGCGGAA ATGCCAGGAG TGTCGCCTTC GCAAATGCCG CCAGGCAGGC 
ATGAGGGAGG AGTGTGTCTT ATCAGAAGAA CAGATCCGCT TGAAGAAACT GAAGCGTCAA 
GAAGAGGAGC AGGCTCAAGC CACATCGGTG TCCCCAAGGG TTTCCTCACC GCCCCAGGTC 
CTGCCACAGC TCAGCCCAGA ACAACTGGGC ATGATTGAGA AGTTGGTGGC TGCCCAGCAA 
CAGTGTAACA GGCGCTCCTT CTCTGACCGA CTTCGAGTCA CGCCTTGGCC CATTGCACCC 
GACCCTCAGA GCCGGGAAGC CCGCCAACAG CGCTTTGCCC ACTTTACTGA GCTGGCCATC 
GTGTCCGTGC AGGAGATTGT TGACTTTGCC AAACAGCTCC CTGGCTTCCT ACAGCTGAGC 
AGGGAGGACC AGATCGCCTT GCTGAAGACC TCTGCGATCG AGGTGATGCT TCTGGAGACA 
TCGCGGAGGT ACAACCCTGG GAGTGAGAGC ATCACCTTCC TCAAGGATTT CAGTTACAAC 
CGGGAAGACT TTGCCAAAGC AGGGCTGCAG GTGGAGTTCA TTAACCCCAT CTTTGAGTTC 
TCCAGATCCA TGAATGAACT GCAACTCAAT GATGCTGAAT TTGCTCTGCT CATAGCCATC 
AGCATCTTCT CTGCAGACCG GCCCAACGTG CAGGACCAGC TCCAAGTAGA GAGACTGCAA 
CACACATATG TGGAGGCCCT GCATGCCTAT GTCTCCATCA ACCACCCCCA CGACCGACTG 
ATGTTCCCAC GGATGCTAAT GAAGCTGGTG AGCCTCCGGA CTTTGAGCAG CGTCCATTCA 
GAGCAAGTGT TTGCACTTCG CCTGCAGGAC AAAAAACTTC CCCCTCTGCT CTCCGAGATC 
TGGGATGTCC ACGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nr1h3 ( XM_006234533.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234595.1 Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa13593
Clone ID Related Accession (Same CDS sequence)	XM_006234533.3 , XM_006234534.2 , XM_006234535.3 , NM_031627.2
Accession Version	XM_006234533.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	oxysterols receptor LXR-alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234533.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGAACT TCGTCCACAG 
AAGCGGAAAA AGGGGCCAGC CCCCAAAATG CTGGGGAACG AGCTATGCAG TGTATGTGGG 
GACAAGGCCT CTGGCTTCCA TTACAATGTG CTGAGCTGCG AGGGCTGCAA GGGATTCTTC 
CGCCGCAGTG TCATCAAGGG AGCACGCTAC ATTTGCCATA GCGGTGGCCA CTGCCCCATG 
GACACCTACA TGCGGCGGAA ATGCCAGGAG TGTCGCCTTC GCAAATGCCG CCAGGCAGGC 
ATGAGGGAGG AGTGTGTCTT ATCAGAAGAA CAGATCCGCT TGAAGAAACT GAAGCGTCAA 
GAAGAGGAGC AGGCTCAAGC CACATCGGTG TCCCCAAGGG TTTCCTCACC GCCCCAGGTC 
CTGCCACAGC TCAGCCCAGA ACAACTGGGC ATGATTGAGA AGTTGGTGGC TGCCCAGCAA 
CAGTGTAACA GGCGCTCCTT CTCTGACCGA CTTCGAGTCA CGCCTTGGCC CATTGCACCC 
GACCCTCAGA GCCGGGAAGC CCGCCAACAG CGCTTTGCCC ACTTTACTGA GCTGGCCATC 
GTGTCCGTGC AGGAGATTGT TGACTTTGCC AAACAGCTCC CTGGCTTCCT ACAGCTGAGC 
AGGGAGGACC AGATCGCCTT GCTGAAGACC TCTGCGATCG AGGTGATGCT TCTGGAGACA 
TCGCGGAGGT ACAACCCTGG GAGTGAGAGC ATCACCTTCC TCAAGGATTT CAGTTACAAC 
CGGGAAGACT TTGCCAAAGC AGGGCTGCAG GTGGAGTTCA TTAACCCCAT CTTTGAGTTC 
TCCAGATCCA TGAATGAACT GCAACTCAAT GATGCTGAAT TTGCTCTGCT CATAGCCATC 
AGCATCTTCT CTGCAGACCG GCCCAACGTG CAGGACCAGC TCCAAGTAGA GAGACTGCAA 
CACACATATG TGGAGGCCCT GCATGCCTAT GTCTCCATCA ACCACCCCCA CGACCGACTG 
ATGTTCCCAC GGATGCTAAT GAAGCTGGTG AGCCTCCGGA CTTTGAGCAG CGTCCATTCA 
GAGCAAGTGT TTGCACTTCG CCTGCAGGAC AAAAAACTTC CCCCTCTGCT CTCCGAGATC 
TGGGATGTCC ACGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234595.1
CDS	127..1464
Translation	MSLWLEAAVPDVSPDSATELWKTEPQDAGDQGGNTCILREEARMPQSTGGALRIGLESSEPTALLPRAETLPEPTELRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGARYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAQATSVSPRVSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRSMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	XM_006234533.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234533.3

ORF Insert Sequence:

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGAACT TCGTCCACAG 
AAGCGGAAAA AGGGGCCAGC CCCCAAAATG CTGGGGAACG AGCTATGCAG TGTATGTGGG 
GACAAGGCCT CTGGCTTCCA TTACAATGTG CTGAGCTGCG AGGGCTGCAA GGGATTCTTC 
CGCCGCAGTG TCATCAAGGG AGCACGCTAC ATTTGCCATA GCGGTGGCCA CTGCCCCATG 
GACACCTACA TGCGGCGGAA ATGCCAGGAG TGTCGCCTTC GCAAATGCCG CCAGGCAGGC 
ATGAGGGAGG AGTGTGTCTT ATCAGAAGAA CAGATCCGCT TGAAGAAACT GAAGCGTCAA 
GAAGAGGAGC AGGCTCAAGC CACATCGGTG TCCCCAAGGG TTTCCTCACC GCCCCAGGTC 
CTGCCACAGC TCAGCCCAGA ACAACTGGGC ATGATTGAGA AGTTGGTGGC TGCCCAGCAA 
CAGTGTAACA GGCGCTCCTT CTCTGACCGA CTTCGAGTCA CGCCTTGGCC CATTGCACCC 
GACCCTCAGA GCCGGGAAGC CCGCCAACAG CGCTTTGCCC ACTTTACTGA GCTGGCCATC 
GTGTCCGTGC AGGAGATTGT TGACTTTGCC AAACAGCTCC CTGGCTTCCT ACAGCTGAGC 
AGGGAGGACC AGATCGCCTT GCTGAAGACC TCTGCGATCG AGGTGATGCT TCTGGAGACA 
TCGCGGAGGT ACAACCCTGG GAGTGAGAGC ATCACCTTCC TCAAGGATTT CAGTTACAAC 
CGGGAAGACT TTGCCAAAGC AGGGCTGCAG GTGGAGTTCA TTAACCCCAT CTTTGAGTTC 
TCCAGATCCA TGAATGAACT GCAACTCAAT GATGCTGAAT TTGCTCTGCT CATAGCCATC 
AGCATCTTCT CTGCAGACCG GCCCAACGTG CAGGACCAGC TCCAAGTAGA GAGACTGCAA 
CACACATATG TGGAGGCCCT GCATGCCTAT GTCTCCATCA ACCACCCCCA CGACCGACTG 
ATGTTCCCAC GGATGCTAAT GAAGCTGGTG AGCCTCCGGA CTTTGAGCAG CGTCCATTCA 
GAGCAAGTGT TTGCACTTCG CCTGCAGGAC AAAAAACTTC CCCCTCTGCT CTCCGAGATC 
TGGGATGTCC ACGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nr1h3 ( XM_006234534.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234596.1 Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa13593
Clone ID Related Accession (Same CDS sequence)	XM_006234533.3 , XM_006234534.2 , XM_006234535.3 , NM_031627.2
Accession Version	XM_006234534.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	oxysterols receptor LXR-alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234534.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGAACT TCGTCCACAG 
AAGCGGAAAA AGGGGCCAGC CCCCAAAATG CTGGGGAACG AGCTATGCAG TGTATGTGGG 
GACAAGGCCT CTGGCTTCCA TTACAATGTG CTGAGCTGCG AGGGCTGCAA GGGATTCTTC 
CGCCGCAGTG TCATCAAGGG AGCACGCTAC ATTTGCCATA GCGGTGGCCA CTGCCCCATG 
GACACCTACA TGCGGCGGAA ATGCCAGGAG TGTCGCCTTC GCAAATGCCG CCAGGCAGGC 
ATGAGGGAGG AGTGTGTCTT ATCAGAAGAA CAGATCCGCT TGAAGAAACT GAAGCGTCAA 
GAAGAGGAGC AGGCTCAAGC CACATCGGTG TCCCCAAGGG TTTCCTCACC GCCCCAGGTC 
CTGCCACAGC TCAGCCCAGA ACAACTGGGC ATGATTGAGA AGTTGGTGGC TGCCCAGCAA 
CAGTGTAACA GGCGCTCCTT CTCTGACCGA CTTCGAGTCA CGCCTTGGCC CATTGCACCC 
GACCCTCAGA GCCGGGAAGC CCGCCAACAG CGCTTTGCCC ACTTTACTGA GCTGGCCATC 
GTGTCCGTGC AGGAGATTGT TGACTTTGCC AAACAGCTCC CTGGCTTCCT ACAGCTGAGC 
AGGGAGGACC AGATCGCCTT GCTGAAGACC TCTGCGATCG AGGTGATGCT TCTGGAGACA 
TCGCGGAGGT ACAACCCTGG GAGTGAGAGC ATCACCTTCC TCAAGGATTT CAGTTACAAC 
CGGGAAGACT TTGCCAAAGC AGGGCTGCAG GTGGAGTTCA TTAACCCCAT CTTTGAGTTC 
TCCAGATCCA TGAATGAACT GCAACTCAAT GATGCTGAAT TTGCTCTGCT CATAGCCATC 
AGCATCTTCT CTGCAGACCG GCCCAACGTG CAGGACCAGC TCCAAGTAGA GAGACTGCAA 
CACACATATG TGGAGGCCCT GCATGCCTAT GTCTCCATCA ACCACCCCCA CGACCGACTG 
ATGTTCCCAC GGATGCTAAT GAAGCTGGTG AGCCTCCGGA CTTTGAGCAG CGTCCATTCA 
GAGCAAGTGT TTGCACTTCG CCTGCAGGAC AAAAAACTTC CCCCTCTGCT CTCCGAGATC 
TGGGATGTCC ACGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234596.1
CDS	127..1464
Translation	MSLWLEAAVPDVSPDSATELWKTEPQDAGDQGGNTCILREEARMPQSTGGALRIGLESSEPTALLPRAETLPEPTELRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGARYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAQATSVSPRVSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRSMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	XM_006234534.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234534.2

ORF Insert Sequence:

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGAACT TCGTCCACAG 
AAGCGGAAAA AGGGGCCAGC CCCCAAAATG CTGGGGAACG AGCTATGCAG TGTATGTGGG 
GACAAGGCCT CTGGCTTCCA TTACAATGTG CTGAGCTGCG AGGGCTGCAA GGGATTCTTC 
CGCCGCAGTG TCATCAAGGG AGCACGCTAC ATTTGCCATA GCGGTGGCCA CTGCCCCATG 
GACACCTACA TGCGGCGGAA ATGCCAGGAG TGTCGCCTTC GCAAATGCCG CCAGGCAGGC 
ATGAGGGAGG AGTGTGTCTT ATCAGAAGAA CAGATCCGCT TGAAGAAACT GAAGCGTCAA 
GAAGAGGAGC AGGCTCAAGC CACATCGGTG TCCCCAAGGG TTTCCTCACC GCCCCAGGTC 
CTGCCACAGC TCAGCCCAGA ACAACTGGGC ATGATTGAGA AGTTGGTGGC TGCCCAGCAA 
CAGTGTAACA GGCGCTCCTT CTCTGACCGA CTTCGAGTCA CGCCTTGGCC CATTGCACCC 
GACCCTCAGA GCCGGGAAGC CCGCCAACAG CGCTTTGCCC ACTTTACTGA GCTGGCCATC 
GTGTCCGTGC AGGAGATTGT TGACTTTGCC AAACAGCTCC CTGGCTTCCT ACAGCTGAGC 
AGGGAGGACC AGATCGCCTT GCTGAAGACC TCTGCGATCG AGGTGATGCT TCTGGAGACA 
TCGCGGAGGT ACAACCCTGG GAGTGAGAGC ATCACCTTCC TCAAGGATTT CAGTTACAAC 
CGGGAAGACT TTGCCAAAGC AGGGCTGCAG GTGGAGTTCA TTAACCCCAT CTTTGAGTTC 
TCCAGATCCA TGAATGAACT GCAACTCAAT GATGCTGAAT TTGCTCTGCT CATAGCCATC 
AGCATCTTCT CTGCAGACCG GCCCAACGTG CAGGACCAGC TCCAAGTAGA GAGACTGCAA 
CACACATATG TGGAGGCCCT GCATGCCTAT GTCTCCATCA ACCACCCCCA CGACCGACTG 
ATGTTCCCAC GGATGCTAAT GAAGCTGGTG AGCCTCCGGA CTTTGAGCAG CGTCCATTCA 
GAGCAAGTGT TTGCACTTCG CCTGCAGGAC AAAAAACTTC CCCCTCTGCT CTCCGAGATC 
TGGGATGTCC ACGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nr1h3 ( XM_006234535.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234597.1 Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X2, mRNA.

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CloneID	ORa13593
Clone ID Related Accession (Same CDS sequence)	XM_006234533.3 , XM_006234534.2 , XM_006234535.3 , NM_031627.2
Accession Version	XM_006234535.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	oxysterols receptor LXR-alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234535.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGAACT TCGTCCACAG 
AAGCGGAAAA AGGGGCCAGC CCCCAAAATG CTGGGGAACG AGCTATGCAG TGTATGTGGG 
GACAAGGCCT CTGGCTTCCA TTACAATGTG CTGAGCTGCG AGGGCTGCAA GGGATTCTTC 
CGCCGCAGTG TCATCAAGGG AGCACGCTAC ATTTGCCATA GCGGTGGCCA CTGCCCCATG 
GACACCTACA TGCGGCGGAA ATGCCAGGAG TGTCGCCTTC GCAAATGCCG CCAGGCAGGC 
ATGAGGGAGG AGTGTGTCTT ATCAGAAGAA CAGATCCGCT TGAAGAAACT GAAGCGTCAA 
GAAGAGGAGC AGGCTCAAGC CACATCGGTG TCCCCAAGGG TTTCCTCACC GCCCCAGGTC 
CTGCCACAGC TCAGCCCAGA ACAACTGGGC ATGATTGAGA AGTTGGTGGC TGCCCAGCAA 
CAGTGTAACA GGCGCTCCTT CTCTGACCGA CTTCGAGTCA CGCCTTGGCC CATTGCACCC 
GACCCTCAGA GCCGGGAAGC CCGCCAACAG CGCTTTGCCC ACTTTACTGA GCTGGCCATC 
GTGTCCGTGC AGGAGATTGT TGACTTTGCC AAACAGCTCC CTGGCTTCCT ACAGCTGAGC 
AGGGAGGACC AGATCGCCTT GCTGAAGACC TCTGCGATCG AGGTGATGCT TCTGGAGACA 
TCGCGGAGGT ACAACCCTGG GAGTGAGAGC ATCACCTTCC TCAAGGATTT CAGTTACAAC 
CGGGAAGACT TTGCCAAAGC AGGGCTGCAG GTGGAGTTCA TTAACCCCAT CTTTGAGTTC 
TCCAGATCCA TGAATGAACT GCAACTCAAT GATGCTGAAT TTGCTCTGCT CATAGCCATC 
AGCATCTTCT CTGCAGACCG GCCCAACGTG CAGGACCAGC TCCAAGTAGA GAGACTGCAA 
CACACATATG TGGAGGCCCT GCATGCCTAT GTCTCCATCA ACCACCCCCA CGACCGACTG 
ATGTTCCCAC GGATGCTAAT GAAGCTGGTG AGCCTCCGGA CTTTGAGCAG CGTCCATTCA 
GAGCAAGTGT TTGCACTTCG CCTGCAGGAC AAAAAACTTC CCCCTCTGCT CTCCGAGATC 
TGGGATGTCC ACGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234597.1
CDS	340..1677
Translation	MSLWLEAAVPDVSPDSATELWKTEPQDAGDQGGNTCILREEARMPQSTGGALRIGLESSEPTALLPRAETLPEPTELRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGARYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAQATSVSPRVSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRSMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	XM_006234535.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234535.3

ORF Insert Sequence:

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGAACT TCGTCCACAG 
AAGCGGAAAA AGGGGCCAGC CCCCAAAATG CTGGGGAACG AGCTATGCAG TGTATGTGGG 
GACAAGGCCT CTGGCTTCCA TTACAATGTG CTGAGCTGCG AGGGCTGCAA GGGATTCTTC 
CGCCGCAGTG TCATCAAGGG AGCACGCTAC ATTTGCCATA GCGGTGGCCA CTGCCCCATG 
GACACCTACA TGCGGCGGAA ATGCCAGGAG TGTCGCCTTC GCAAATGCCG CCAGGCAGGC 
ATGAGGGAGG AGTGTGTCTT ATCAGAAGAA CAGATCCGCT TGAAGAAACT GAAGCGTCAA 
GAAGAGGAGC AGGCTCAAGC CACATCGGTG TCCCCAAGGG TTTCCTCACC GCCCCAGGTC 
CTGCCACAGC TCAGCCCAGA ACAACTGGGC ATGATTGAGA AGTTGGTGGC TGCCCAGCAA 
CAGTGTAACA GGCGCTCCTT CTCTGACCGA CTTCGAGTCA CGCCTTGGCC CATTGCACCC 
GACCCTCAGA GCCGGGAAGC CCGCCAACAG CGCTTTGCCC ACTTTACTGA GCTGGCCATC 
GTGTCCGTGC AGGAGATTGT TGACTTTGCC AAACAGCTCC CTGGCTTCCT ACAGCTGAGC 
AGGGAGGACC AGATCGCCTT GCTGAAGACC TCTGCGATCG AGGTGATGCT TCTGGAGACA 
TCGCGGAGGT ACAACCCTGG GAGTGAGAGC ATCACCTTCC TCAAGGATTT CAGTTACAAC 
CGGGAAGACT TTGCCAAAGC AGGGCTGCAG GTGGAGTTCA TTAACCCCAT CTTTGAGTTC 
TCCAGATCCA TGAATGAACT GCAACTCAAT GATGCTGAAT TTGCTCTGCT CATAGCCATC 
AGCATCTTCT CTGCAGACCG GCCCAACGTG CAGGACCAGC TCCAAGTAGA GAGACTGCAA 
CACACATATG TGGAGGCCCT GCATGCCTAT GTCTCCATCA ACCACCCCCA CGACCGACTG 
ATGTTCCCAC GGATGCTAAT GAAGCTGGTG AGCCTCCGGA CTTTGAGCAG CGTCCATTCA 
GAGCAAGTGT TTGCACTTCG CCTGCAGGAC AAAAAACTTC CCCCTCTGCT CTCCGAGATC 
TGGGATGTCC ACGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nr1h3 ( XM_006234537.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006234599.1 Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X4, mRNA.

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CloneID	ORa26092
Clone ID Related Accession (Same CDS sequence)	XM_006234537.1
Accession Version	XM_006234537.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	oxysterols receptor LXR-alpha isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGGTGT CTTATCAGAA 
GAACAGATCC GCTTGAAGAA ACTGAAGCGT CAAGAAGAGG AGCAGGCTCA AGCCACATCG 
GTGTCCCCAA GGGTTTCCTC ACCGCCCCAG GTCCTGCCAC AGCTCAGCCC AGAACAACTG 
GGCATGATTG AGAAGTTGGT GGCTGCCCAG CAACAGTGTA ACAGGCGCTC CTTCTCTGAC 
CGACTTCGAG TCACGCCTTG GCCCATTGCA CCCGACCCTC AGAGCCGGGA AGCCCGCCAA 
CAGCGCTTTG CCCACTTTAC TGAGCTGGCC ATCGTGTCCG TGCAGGAGAT TGTTGACTTT 
GCCAAACAGC TCCCTGGCTT CCTACAGCTG AGCAGGGAGG ACCAGATCGC CTTGCTGAAG 
ACCTCTGCGA TCGAGGTGAT GCTTCTGGAG ACATCGCGGA GGTACAACCC TGGGAGTGAG 
AGCATCACCT TCCTCAAGGA TTTCAGTTAC AACCGGGAAG ACTTTGCCAA AGCAGGGCTG 
CAGGTGGAGT TCATTAACCC CATCTTTGAG TTCTCCAGAT CCATGAATGA ACTGCAACTC 
AATGATGCTG AATTTGCTCT GCTCATAGCC ATCAGCATCT TCTCTGCAGA CCGGCCCAAC 
GTGCAGGACC AGCTCCAAGT AGAGAGACTG CAACACACAT ATGTGGAGGC CCTGCATGCC 
TATGTCTCCA TCAACCACCC CCACGACCGA CTGATGTTCC CACGGATGCT AATGAAGCTG 
GTGAGCCTCC GGACTTTGAG CAGCGTCCAT TCAGAGCAAG TGTTTGCACT TCGCCTGCAG 
GACAAAAAAC TTCCCCCTCT GCTCTCCGAG ATCTGGGATG TCCACGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006234599.1
CDS	75..1145
Translation	MSLWLEAAVPDVSPDSATELWKTEPQDAGDQGGNTCILREEARMPQSTGGALRIGLESSEPTALLPRAETLPEPTGVLSEEQIRLKKLKRQEEEQAQATSVSPRVSSPPQVLPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPIAPDPQSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRSMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	XM_006234537.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus nuclear receptor subfamily 1, group H, member 3 (Nr1h3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006234537.1

ORF Insert Sequence:

ATGTCCTTGT GGCTGGAGGC CGCAGTGCCT GATGTTTCTC CTGACTCTGC AACGGAGTTG 
TGGAAGACAG AACCTCAAGA TGCAGGAGAC CAGGGAGGCA ACACTTGCAT CCTTAGGGAG 
GAAGCCAGGA TGCCCCAATC AACTGGGGGT GCTTTAAGGA TAGGGTTGGA GTCATCCGAG 
CCTACAGCCC TGCTCCCCAG GGCAGAGACC CTCCCAGAGC CTACAGGTGT CTTATCAGAA 
GAACAGATCC GCTTGAAGAA ACTGAAGCGT CAAGAAGAGG AGCAGGCTCA AGCCACATCG 
GTGTCCCCAA GGGTTTCCTC ACCGCCCCAG GTCCTGCCAC AGCTCAGCCC AGAACAACTG 
GGCATGATTG AGAAGTTGGT GGCTGCCCAG CAACAGTGTA ACAGGCGCTC CTTCTCTGAC 
CGACTTCGAG TCACGCCTTG GCCCATTGCA CCCGACCCTC AGAGCCGGGA AGCCCGCCAA 
CAGCGCTTTG CCCACTTTAC TGAGCTGGCC ATCGTGTCCG TGCAGGAGAT TGTTGACTTT 
GCCAAACAGC TCCCTGGCTT CCTACAGCTG AGCAGGGAGG ACCAGATCGC CTTGCTGAAG 
ACCTCTGCGA TCGAGGTGAT GCTTCTGGAG ACATCGCGGA GGTACAACCC TGGGAGTGAG 
AGCATCACCT TCCTCAAGGA TTTCAGTTAC AACCGGGAAG ACTTTGCCAA AGCAGGGCTG 
CAGGTGGAGT TCATTAACCC CATCTTTGAG TTCTCCAGAT CCATGAATGA ACTGCAACTC 
AATGATGCTG AATTTGCTCT GCTCATAGCC ATCAGCATCT TCTCTGCAGA CCGGCCCAAC 
GTGCAGGACC AGCTCCAAGT AGAGAGACTG CAACACACAT ATGTGGAGGC CCTGCATGCC 
TATGTCTCCA TCAACCACCC CCACGACCGA CTGATGTTCC CACGGATGCT AATGAAGCTG 
GTGAGCCTCC GGACTTTGAG CAGCGTCCAT TCAGAGCAAG TGTTTGCACT TCGCCTGCAG 
GACAAAAAAC TTCCCCCTCT GCTCTCCGAG ATCTGGGATG TCCACGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Diosgenin prevents high-fat diet-induced rat non-alcoholic fatty liver disease through the AMPK and LXR signaling pathways.
International journal of molecular medicine41(2)1089-1095(2018 Feb)
Cheng S,Liang S,Liu Q,Deng Z,Zhang Y,Du J,Zhang Y,Li S,Cheng B,Ling C

Insulin induction of SREBP-1c in rodent liver requires LXR?-C/EBP? complex.
Proceedings of the National Academy of Sciences of the United States of America113(29)8182-7(2016 07)
Tian J,Goldstein JL,Brown MS

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.
Nature535(7611)303-7(2016 07)
Hsieh J,Koseki M,Molusky MM,Yakushiji E,Ichi I,Westerterp M,Iqbal J,Chan RB,Abramowicz S,Tascau L,Takiguchi S,Yamashita S,Welch CL,Di Paolo G,Hussain MM,Lefkowitch JH,Rader DJ,Tall AR

Liver X Receptor Agonist TO901317 Prevents Diacylglycerols Accumulation in the Heart of Streptozotocin-Diabetic Rats.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology39(1)350-9(2016)
Harasiuk D,Baranowski M,Zabielski P,Chabowski A,G?rski J

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Nr1h3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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