Rassf5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rassf5
Entrez Gene ID	54355
Full Name	Ras association domain family member 5
Synonyms	Maxp1,Nore1
General protein information	Preferred Names Ras association domain family member 5 Names ras association domain-containing protein 5 Ras association (RalGDS/AF-6) domain family member 5 new ras effector 1 novel ras effector 1 protein interacting with guanine nucleotide exchange factor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q13
Summary	interacts with guanine nucleotide exchange factor Mss4 [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006249796.3	XP_006249858.1	ras association domain-containing protein 5 isoform X1
NM_019365.3	NP_062238.1	ras association domain-containing protein 5
XM_008769494.2	XP_008767716.1	ras association domain-containing protein 5 isoform X2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RASSF5	NP_001107232.1
Rattus norvegicus (Norway rat)	Rassf5	NP_062238.1
Homo sapiens (human)	RASSF5	NP_872604.1
Danio rerio (zebrafish)	LOC100150414	XP_001920863.4
	RASSF5	XP_001087653.1
Mus musculus (house mouse)	Rassf5	NP_061220.2

Gene Ontology
Bibliography

Related articles in PubMed

Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.
Nakamura T, Yasuda S, Nagai H, Koinuma S, Morishita S, Goto A, Kinashi T, Wada N
Genes to cells : devoted to molecular & cellular mechanisms18(11)1020-31(2013 Nov)

Mdm2 associates with Ras effector NORE1 to induce the degradation of oncoprotein HIPK1.
Lee D, Park SJ, Sung KS, Park J, Lee SB, Park SY, Lee HJ, Ahn JW, Choi SJ, Lee SG, Kim SH, Kim DH, Kim J, Kim Y, Choi CY
EMBO reports13(2)163-9(2012 Feb)

Ras signaling in NGF reduction and TNF-?-related pancreatic ? cell apoptosis in hyperglycemic rats.
Gezginci-Oktayoglu S, Bolkent S
Apoptosis : an international journal on programmed cell death17(1)14-24(2012 Jan)

Deficiency of Rap1-binding protein RAPL causes lymphoproliferative disorders through mislocalization of p27kip1.
Katagiri K, Ueda Y, Tomiyama T, Yasuda K, Toda Y, Ikehara S, Nakayama KI, Kinashi T
Immunity34(1)24-38(2011 Jan)

Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma.
Shinmura K, Tao H, Nagura K, Goto M, Matsuura S, Mochizuki T, Suzuki K, Tanahashi M, Niwa H, Ogawa H, Sugimura H
Lung cancer (Amsterdam, Netherlands)71(1)19-27(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

specific activation of Rap1B contributes to neuronal polarization via interaction with RalA and Nore1A in addition to PI3-kinase.
Title: Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.

Apoptotic Ras effector molecules RASSF1 and NORE1 play important role in NGF reduction and TNF-alpha-related pancreatic beta cell apoptosis in hyperglycemic rats.
Title: Ras signaling in NGF reduction and TNF-?-related pancreatic ? cell apoptosis in hyperglycemic rats.

Nore1 is a member of a family of Ras effector/tumor suppressors that includes RASSF1
Title: The pro-apoptotic Ras effector Nore1 may serve as a Ras-regulated tumor suppressor in the lung.

The following Rassf5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rassf5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa04565	NM_019365.3 Latest version!	Rattus norvegicus Ras association domain family member 5 (Rassf5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa35320	XM_006249796.3 Latest version!	Rattus norvegicus Ras association domain family member 5 (Rassf5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa43437	XM_008769494.2 Latest version!	Rattus norvegicus Ras association domain family member 5 (Rassf5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rassf5 ( NM_019365.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062238.1 Rattus norvegicus Ras association domain family member 5 (Rassf5), mRNA.

Price & Availability↑

CloneID	ORa04565
Clone ID Related Accession (Same CDS sequence)	NM_019365.3
Accession Version	NM_019365.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	ras association domain-containing protein 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF002251.1. On Nov 27, 2008 this sequence version replaced NM_019365.2. ##Evidence-Data-START## Transcript exon combination :: AF002251.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTCCC CGGCCATTGG GCAGCGTCCC TACCCGCTGC TGCTAGACCC CGAGCCGCCG 
CGGTATCTGC AGAGCCTGGG TGGCACCGAG CCGCCACCGC CCGCCCGGCC GCGTCGCTGT 
ATCCCCACGG CCCTGATCTC CGCGTCCGGG GCGTCAGAGG GTCGCGGTAG CAGGAGGAAT 
GCCCGGGGGG ACCCGGAGCC CACGCCCCGG GACTGCCGAC ACGCTCGCCC TGTCCGGCCC 
GGTCTGCAGC AGAGACTGCG GCGGCGACCT GGGTCGCACC GACCCCGCGA CGTGAGGAGC 
ATCTTCGAGC AACCGCAGGA TCCCCGCGTC TTAGCCGAGA GAGGAGAGGG ACACCGTTTC 
GCGGAATTGG CGCTCCGGGG TGGCCCGGGC TGGTGTGACC TGTGCGGACG AGAGGTGCTG 
CGGCAGGCGC TGCGCTGCGC TAATTGTAAA TTCACCTGCC ACCCAGAGTG CCGCAGCCTG 
ATCCAGCTGG ACTGCAGACA GAAGGAGGGC CCTGCCCTGG ACAGACAGTC TCCAGAAAGC 
ACCCTCACCC CAACCTTCAA CAAGAATGTC TGTAAGGCTG TGGAGGAGAC ACAGCACCCG 
CCCACCATAC AGGAGATCAA GCAGAAGATT GACAGCTATA ACAGCCGGGA GAAGCACTGC 
CTGGGCATGA AGTTGAGTGA AGATGGCACC TACACAGGTT TCATCAAAGT GCATTTGAAA 
CTCCGCCGGC CAGTGACGGT GCCTGCTGGG ATTCGGCCCC AGTCCATCTA TGATGCCATT 
AAGGAAGTGA ACCCTGCAGC TACCACAGAC AAGCGGACAT CCTTCTACCT GCCACTTGAC 
GCCATCAAGC AGCTACACAT TAGCAGCAGC ACCACTGTCA GTGAGGTCAT CCAGGGGCTG 
CTCAAGAAAT TCATGGTTGT GGACAACCCA CAGAAGTTTG CCCTTTTTAA GCGGATACAC 
AAAGATGGAC AAGTGCTCTT CCAGAAACTC TCCATCGCTG ACTGCCCTCT CTACCTTCGT 
CTGCTCGCTG GTCCTGACAC CGACGTGCTC AGCTTTGTGC TCAAGGAGAA TGAAACCGGA 
GACGTAGAGT GGGATGCCTT TTCCATTCCT GAACTCCAGA ACTTCTTAAC TATCCTGGAA 
AAAGAGGAGC AGGACAAGAT CCATCAACTG CAGAAGAAGT ACAACAAATT CCGGCAGAAA 
CTGGAGGAGG CCTTACGAGA GTCCCAAGGG AAGCCTGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062238.1
CDS	129..1370
Translation	MASPAIGQRPYPLLLDPEPPRYLQSLGGTEPPPPARPRRCIPTALISASGASEGRGSRRNARGDPEPTPRDCRHARPVRPGLQQRLRRRPGSHRPRDVRSIFEQPQDPRVLAERGEGHRFAELALRGGPGWCDLCGREVLRQALRCANCKFTCHPECRSLIQLDCRQKEGPALDRQSPESTLTPTFNKNVCKAVEETQHPPTIQEIKQKIDSYNSREKHCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNPAATTDKRTSFYLPLDAIKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGDVEWDAFSIPELQNFLTILEKEEQDKIHQLQKKYNKFRQKLEEALRESQGKPG

Target ORF information:

RefSeq Version	NM_019365.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Ras association domain family member 5 (Rassf5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019365.3

ORF Insert Sequence:

ATGGCGTCCC CGGCCATTGG GCAGCGTCCC TACCCGCTGC TGCTAGACCC CGAGCCGCCG 
CGGTATCTGC AGAGCCTGGG TGGCACCGAG CCGCCACCGC CCGCCCGGCC GCGTCGCTGT 
ATCCCCACGG CCCTGATCTC CGCGTCCGGG GCGTCAGAGG GTCGCGGTAG CAGGAGGAAT 
GCCCGGGGGG ACCCGGAGCC CACGCCCCGG GACTGCCGAC ACGCTCGCCC TGTCCGGCCC 
GGTCTGCAGC AGAGACTGCG GCGGCGACCT GGGTCGCACC GACCCCGCGA CGTGAGGAGC 
ATCTTCGAGC AACCGCAGGA TCCCCGCGTC TTAGCCGAGA GAGGAGAGGG ACACCGTTTC 
GCGGAATTGG CGCTCCGGGG TGGCCCGGGC TGGTGTGACC TGTGCGGACG AGAGGTGCTG 
CGGCAGGCGC TGCGCTGCGC TAATTGTAAA TTCACCTGCC ACCCAGAGTG CCGCAGCCTG 
ATCCAGCTGG ACTGCAGACA GAAGGAGGGC CCTGCCCTGG ACAGACAGTC TCCAGAAAGC 
ACCCTCACCC CAACCTTCAA CAAGAATGTC TGTAAGGCTG TGGAGGAGAC ACAGCACCCG 
CCCACCATAC AGGAGATCAA GCAGAAGATT GACAGCTATA ACAGCCGGGA GAAGCACTGC 
CTGGGCATGA AGTTGAGTGA AGATGGCACC TACACAGGTT TCATCAAAGT GCATTTGAAA 
CTCCGCCGGC CAGTGACGGT GCCTGCTGGG ATTCGGCCCC AGTCCATCTA TGATGCCATT 
AAGGAAGTGA ACCCTGCAGC TACCACAGAC AAGCGGACAT CCTTCTACCT GCCACTTGAC 
GCCATCAAGC AGCTACACAT TAGCAGCAGC ACCACTGTCA GTGAGGTCAT CCAGGGGCTG 
CTCAAGAAAT TCATGGTTGT GGACAACCCA CAGAAGTTTG CCCTTTTTAA GCGGATACAC 
AAAGATGGAC AAGTGCTCTT CCAGAAACTC TCCATCGCTG ACTGCCCTCT CTACCTTCGT 
CTGCTCGCTG GTCCTGACAC CGACGTGCTC AGCTTTGTGC TCAAGGAGAA TGAAACCGGA 
GACGTAGAGT GGGATGCCTT TTCCATTCCT GAACTCCAGA ACTTCTTAAC TATCCTGGAA 
AAAGAGGAGC AGGACAAGAT CCATCAACTG CAGAAGAAGT ACAACAAATT CCGGCAGAAA 
CTGGAGGAGG CCTTACGAGA GTCCCAAGGG AAGCCTGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rassf5 ( XM_006249796.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249858.1 Rattus norvegicus Ras association domain family member 5 (Rassf5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa35320
Clone ID Related Accession (Same CDS sequence)	XM_006249796.3
Accession Version	XM_006249796.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1281bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ras association domain-containing protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249796.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTTTGG TCGGTGGTTG GAACTTTGAA GACATTGATT TCTCAGACTC ACAGGCATGT 
GTGAGGAGTG AGGCCCGGGC AGGCTGTCCG GCTGGCAGTC TGTTTGGTGG GGGCACTTTT 
ATCTTATCAA GCGAAAAGCC CAGGAATAGA AAGTTTTCCA TTGGAGGAGG TGGCGGGGAC 
AGGATCTCAG CTGAGGAGGG GGTGACATCC ATGAGGTCTC AGGTGCCTAT TCTGGGCACA 
GGAAGCCTAG AGCCCTCCGC TGGGCCGGTG TCTCCCTCCT TTGGCGCCAG ACCTAAAGAA 
GAGCTATTGA TCTGCAGACA TCTTAGGATG AGGGAGGGCC CAGATGAGGA GGTGGTGGCC 
GCTTGCTTCA GCACAGTCAC CCTGTGTCTC CAGCGCCTTT TCCAAAGACT CCCGAGGAGT 
CACGGGCTGC CGGGAAAGCC CAGGACCCCA CAGAGGCTCT GCTGCAAGGC CCTGGCTCAT 
GATTGTAAAT TCACCTGCCA CCCAGAGTGC CGCAGCCTGA TCCAGCTGGA CTGCAGACAG 
AAGGAGGGCC CTGCCCTGGA CAGACAGTCT CCAGAAAGCA CCCTCACCCC AACCTTCAAC 
AAGAATGTCT GTAAGGCTGT GGAGGAGACA CAGCACCCGC CCACCATACA GGAGATCAAG 
CAGAAGATTG ACAGCTATAA CAGCCGGGAG AAGCACTGCC TGGGCATGAA GTTGAGTGAA 
GATGGCACCT ACACAGGTTT CATCAAAGTG CATTTGAAAC TCCGCCGGCC AGTGACGGTG 
CCTGCTGGGA TTCGGCCCCA GTCCATCTAT GATGCCATTA AGGAAGTGAA CCCTGCAGCT 
ACCACAGACA AGCGGACATC CTTCTACCTG CCACTTGACG CCATCAAGCA GCTACACATT 
AGCAGCAGCA CCACTGTCAG TGAGGTCATC CAGGGGCTGC TCAAGAAATT CATGGTTGTG 
GACAACCCAC AGAAGTTTGC CCTTTTTAAG CGGATACACA AAGATGGACA AGTGCTCTTC 
CAGAAACTCT CCATCGCTGA CTGCCCTCTC TACCTTCGTC TGCTCGCTGG TCCTGACACC 
GACGTGCTCA GCTTTGTGCT CAAGGAGAAT GAAACCGGAG ACGTAGAGTG GGATGCCTTT 
TCCATTCCTG AACTCCAGAA CTTCTTAACT ATCCTGGAAA AAGAGGAGCA GGACAAGATC 
CATCAACTGC AGAAGAAGTA CAACAAATTC CGGCAGAAAC TGGAGGAGGC CTTACGAGAG 
TCCCAAGGGA AGCCTGGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249858.1
CDS	952..2232
Translation	MTLVGGWNFEDIDFSDSQACVRSEARAGCPAGSLFGGGTFILSSEKPRNRKFSIGGGGGDRISAEEGVTSMRSQVPILGTGSLEPSAGPVSPSFGARPKEELLICRHLRMREGPDEEVVAACFSTVTLCLQRLFQRLPRSHGLPGKPRTPQRLCCKALAHDCKFTCHPECRSLIQLDCRQKEGPALDRQSPESTLTPTFNKNVCKAVEETQHPPTIQEIKQKIDSYNSREKHCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNPAATTDKRTSFYLPLDAIKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGDVEWDAFSIPELQNFLTILEKEEQDKIHQLQKKYNKFRQKLEEALRESQGKPG

Target ORF information:

RefSeq Version	XM_006249796.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Ras association domain family member 5 (Rassf5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249796.3

ORF Insert Sequence:

ATGACTTTGG TCGGTGGTTG GAACTTTGAA GACATTGATT TCTCAGACTC ACAGGCATGT 
GTGAGGAGTG AGGCCCGGGC AGGCTGTCCG GCTGGCAGTC TGTTTGGTGG GGGCACTTTT 
ATCTTATCAA GCGAAAAGCC CAGGAATAGA AAGTTTTCCA TTGGAGGAGG TGGCGGGGAC 
AGGATCTCAG CTGAGGAGGG GGTGACATCC ATGAGGTCTC AGGTGCCTAT TCTGGGCACA 
GGAAGCCTAG AGCCCTCCGC TGGGCCGGTG TCTCCCTCCT TTGGCGCCAG ACCTAAAGAA 
GAGCTATTGA TCTGCAGACA TCTTAGGATG AGGGAGGGCC CAGATGAGGA GGTGGTGGCC 
GCTTGCTTCA GCACAGTCAC CCTGTGTCTC CAGCGCCTTT TCCAAAGACT CCCGAGGAGT 
CACGGGCTGC CGGGAAAGCC CAGGACCCCA CAGAGGCTCT GCTGCAAGGC CCTGGCTCAT 
GATTGTAAAT TCACCTGCCA CCCAGAGTGC CGCAGCCTGA TCCAGCTGGA CTGCAGACAG 
AAGGAGGGCC CTGCCCTGGA CAGACAGTCT CCAGAAAGCA CCCTCACCCC AACCTTCAAC 
AAGAATGTCT GTAAGGCTGT GGAGGAGACA CAGCACCCGC CCACCATACA GGAGATCAAG 
CAGAAGATTG ACAGCTATAA CAGCCGGGAG AAGCACTGCC TGGGCATGAA GTTGAGTGAA 
GATGGCACCT ACACAGGTTT CATCAAAGTG CATTTGAAAC TCCGCCGGCC AGTGACGGTG 
CCTGCTGGGA TTCGGCCCCA GTCCATCTAT GATGCCATTA AGGAAGTGAA CCCTGCAGCT 
ACCACAGACA AGCGGACATC CTTCTACCTG CCACTTGACG CCATCAAGCA GCTACACATT 
AGCAGCAGCA CCACTGTCAG TGAGGTCATC CAGGGGCTGC TCAAGAAATT CATGGTTGTG 
GACAACCCAC AGAAGTTTGC CCTTTTTAAG CGGATACACA AAGATGGACA AGTGCTCTTC 
CAGAAACTCT CCATCGCTGA CTGCCCTCTC TACCTTCGTC TGCTCGCTGG TCCTGACACC 
GACGTGCTCA GCTTTGTGCT CAAGGAGAAT GAAACCGGAG ACGTAGAGTG GGATGCCTTT 
TCCATTCCTG AACTCCAGAA CTTCTTAACT ATCCTGGAAA AAGAGGAGCA GGACAAGATC 
CATCAACTGC AGAAGAAGTA CAACAAATTC CGGCAGAAAC TGGAGGAGGC CTTACGAGAG 
TCCCAAGGGA AGCCTGGGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rassf5 ( XM_008769494.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008767716.1 Rattus norvegicus Ras association domain family member 5 (Rassf5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa43437
Clone ID Related Accession (Same CDS sequence)	XM_008769494.2
Accession Version	XM_008769494.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ras association domain-containing protein 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769494.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCGTAG ACAGCAGCAT GAGCAGCGGG TACTGCAGCC TGGATGAGGA ACTGGAAGAT 
TGCTTCTTTA CGGCTAAGAC CACCTTTTTC AGGAATGTTC AGAGCAAACA CTCTTCAAAG 
AATGTCTGTA AGGCTGTGGA GGAGACACAG CACCCGCCCA CCATACAGGA GATCAAGCAG 
AAGATTGACA GCTATAACAG CCGGGAGAAG CACTGCCTGG GCATGAAGTT GAGTGAAGAT 
GGCACCTACA CAGGTTTCAT CAAAGTGCAT TTGAAACTCC GCCGGCCAGT GACGGTGCCT 
GCTGGGATTC GGCCCCAGTC CATCTATGAT GCCATTAAGG AAGTGAACCC TGCAGCTACC 
ACAGACAAGC GGACATCCTT CTACCTGCCA CTTGACGCCA TCAAGCAGCT ACACATTAGC 
AGCAGCACCA CTGTCAGTGA GGTCATCCAG GGGCTGCTCA AGAAATTCAT GGTTGTGGAC 
AACCCACAGA AGTTTGCCCT TTTTAAGCGG ATACACAAAG ATGGACAAGT GCTCTTCCAG 
AAACTCTCCA TCGCTGACTG CCCTCTCTAC CTTCGTCTGC TCGCTGGTCC TGACACCGAC 
GTGCTCAGCT TTGTGCTCAA GGAGAATGAA ACCGGAGACG TAGAGTGGGA TGCCTTTTCC 
ATTCCTGAAC TCCAGAACTT CTTAACTATC CTGGAAAAAG AGGAGCAGGA CAAGATCCAT 
CAACTGCAGA AGAAGTACAA CAAATTCCGG CAGAAACTGG AGGAGGCCTT ACGAGAGTCC 
CAAGGGAAGC CTGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008767716.1
CDS	245..1042
Translation	MTVDSSMSSGYCSLDEELEDCFFTAKTTFFRNVQSKHSSKNVCKAVEETQHPPTIQEIKQKIDSYNSREKHCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNPAATTDKRTSFYLPLDAIKQLHISSSTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADCPLYLRLLAGPDTDVLSFVLKENETGDVEWDAFSIPELQNFLTILEKEEQDKIHQLQKKYNKFRQKLEEALRESQGKPG

Target ORF information:

RefSeq Version	XM_008769494.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Ras association domain family member 5 (Rassf5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008769494.2

ORF Insert Sequence:

ATGACCGTAG ACAGCAGCAT GAGCAGCGGG TACTGCAGCC TGGATGAGGA ACTGGAAGAT 
TGCTTCTTTA CGGCTAAGAC CACCTTTTTC AGGAATGTTC AGAGCAAACA CTCTTCAAAG 
AATGTCTGTA AGGCTGTGGA GGAGACACAG CACCCGCCCA CCATACAGGA GATCAAGCAG 
AAGATTGACA GCTATAACAG CCGGGAGAAG CACTGCCTGG GCATGAAGTT GAGTGAAGAT 
GGCACCTACA CAGGTTTCAT CAAAGTGCAT TTGAAACTCC GCCGGCCAGT GACGGTGCCT 
GCTGGGATTC GGCCCCAGTC CATCTATGAT GCCATTAAGG AAGTGAACCC TGCAGCTACC 
ACAGACAAGC GGACATCCTT CTACCTGCCA CTTGACGCCA TCAAGCAGCT ACACATTAGC 
AGCAGCACCA CTGTCAGTGA GGTCATCCAG GGGCTGCTCA AGAAATTCAT GGTTGTGGAC 
AACCCACAGA AGTTTGCCCT TTTTAAGCGG ATACACAAAG ATGGACAAGT GCTCTTCCAG 
AAACTCTCCA TCGCTGACTG CCCTCTCTAC CTTCGTCTGC TCGCTGGTCC TGACACCGAC 
GTGCTCAGCT TTGTGCTCAA GGAGAATGAA ACCGGAGACG TAGAGTGGGA TGCCTTTTCC 
ATTCCTGAAC TCCAGAACTT CTTAACTATC CTGGAAAAAG AGGAGCAGGA CAAGATCCAT 
CAACTGCAGA AGAAGTACAA CAAATTCCGG CAGAAACTGG AGGAGGCCTT ACGAGAGTCC 
CAAGGGAAGC CTGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.
Genes to cells : devoted to molecular & cellular mechanisms18(11)1020-31(2013 Nov)
Nakamura T,Yasuda S,Nagai H,Koinuma S,Morishita S,Goto A,Kinashi T,Wada N

Mdm2 associates with Ras effector NORE1 to induce the degradation of oncoprotein HIPK1.
EMBO reports13(2)163-9(2012 Feb)
Lee D,Park SJ,Sung KS,Park J,Lee SB,Park SY,Lee HJ,Ahn JW,Choi SJ,Lee SG,Kim SH,Kim DH,Kim J,Kim Y,Choi CY

Ras signaling in NGF reduction and TNF-?-related pancreatic ? cell apoptosis in hyperglycemic rats.
Apoptosis : an international journal on programmed cell death17(1)14-24(2012 Jan)
Gezginci-Oktayoglu S,Bolkent S

Deficiency of Rap1-binding protein RAPL causes lymphoproliferative disorders through mislocalization of p27kip1.
Immunity34(1)24-38(2011 Jan)
Katagiri K,Ueda Y,Tomiyama T,Yasuda K,Toda Y,Ikehara S,Nakayama KI,Kinashi T

Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma.
Lung cancer (Amsterdam, Netherlands)71(1)19-27(2011 Jan)
Shinmura K,Tao H,Nagura K,Goto M,Matsuura S,Mochizuki T,Suzuki K,Tanahashi M,Niwa H,Ogawa H,Sugimura H

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Rassf5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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