RASSF5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RASSF5
Entrez Gene ID	83593
Full Name	Ras association domain family member 5
Synonyms	Maxp1,NORE1,NORE1A,NORE1B,RAPL,RASSF3
General protein information	Preferred Names Ras association domain family member 5 Names ras association domain-containing protein 5 Rap1-binding protein Ras association (RalGDS/AF-6) domain family 5 Ras association (RalGDS/AF-6) domain family member 5 Ras effector-like protein new ras effector 1 novel Ras effector 1 regulator for cell adhesion and polarization enriched in lymphoid tissue tumor suppressor RASSF3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.1
Summary	This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	607020

mRNA and Protein(s)

mRNA	Protein	Name
NM_182663.3	NP_872604.1	ras association domain-containing protein 5 isoform A
NM_182664.4	NP_872605.1	ras association domain-containing protein 5 isoform B
NM_182663.4	NP_872604.1	ras association domain-containing protein 5 isoform A
NM_182665.3	NP_872606.1	ras association domain-containing protein 5 isoform C
NM_182664.3	NP_872605.1	ras association domain-containing protein 5 isoform B
NM_182665.4	NP_872606.1	ras association domain-containing protein 5 isoform C

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RASSF5	NP_001107232.1
Rattus norvegicus (Norway rat)	Rassf5	NP_062238.1
Homo sapiens (human)	RASSF5	NP_872604.1
Danio rerio (zebrafish)	LOC100150414	XP_001920863.4
	RASSF5	XP_001087653.1
Mus musculus (house mouse)	Rassf5	NP_061220.2

Gene Ontology
Bibliography

Related articles in PubMed

Ubc9 Binds to ADAP and Is Required for Rap1 Membrane Recruitment, Rac1 Activation, and Integrin-Mediated T Cell Adhesion.
Xiong Y, Ye C, Yang N, Li M, Liu H
Journal of immunology (Baltimore, Md. : 1950)199(12)4142-4154(2017 Dec)

Nonstructural protein 5B promotes degradation of the NORE1A tumor suppressor to facilitate hepatitis C virus replication.
Arora P, Basu A, Schmidt ML, Clark GJ, Donninger H, Nichols DB, Calvisi DF, Kaushik-Basu N
Hepatology (Baltimore, Md.)65(5)1462-1477(2017 05)

The emerging roles of RASSF5 in human malignancy.
Li S, Teng J, Li H, Zheng J, Chen F
Anti-cancer agents in medicinal chemistry(2017 Mar)

MiR-214 regulates oral cancer KB cell apoptosis through targeting RASSF5.
Li TK, Yin K, Chen Z, Bao Y, Zhang SX
Genetics and molecular research : GMR16(1)(2017 Mar)

NORE1A induction by membrane-bound CD40L (mCD40L) contributes to CD40L-induced cell death and G1 growth arrest in p21-mediated mechanism.
Elmetwali T, Salman A, Palmer DH
Cell death & disease7e2146(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ubc9 is an essential regulator of ADAP where it is required for TCR-induced membrane recruitment of the small GTPase Rap1 and its effector protein RapL.
Title: Ubc9 Binds to ADAP and Is Required for Rap1 Membrane Recruitment, Rac1 Activation, and Integrin-Mediated T Cell Adhesion.

Hepatitis C virus uses NS5B to specifically suppress NORE1A, facilitating viral replication and elevated Ras signaling.
Title: Nonstructural protein 5B promotes degradation of the NORE1A tumor suppressor to facilitate hepatitis C virus replication.

Our study demonstrated that miR-214 expression was elevated and RASSF5 was down regulated in oral cancer. Moreover, miR-214 suppressed KB cell apoptosis through down regulation of RASSF5 expression
Title: MiR-214 regulates oral cancer KB cell apoptosis through targeting RASSF5.

mCD40L-induced cell death mediated by NORE1A expression appeared to be independent of mCD40L-induced cell death mediated by sustained JNK activation since NORE1A inhibition did not affect JNK phosphorylation and vice versa
Title: NORE1A induction by membrane-bound CD40L (mCD40L) contributes to CD40L-induced cell death and G1 growth arrest in p21-mediated mechanism.

Ras induces the formation of a complex between NORE1A and the phosphatase PP1A, promoting the activation of the Rb tumor suppressor by dephosphorylation
Title: Ras Regulates Rb via NORE1A.

The following RASSF5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RASSF5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27551	NM_182665.4 Latest version!	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu28317	NM_182663.4 Latest version!	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$174.50-$244.30 $349.00
OHu17011	NM_182664.4 Latest version!	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$202.30 $289.00
View Old Accession Versions >>
OHu28317	NM_182663.3	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$174.50-$244.30 $349.00
OHu17011	NM_182664.3	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$202.30 $289.00
OHu27551	NM_182665.3	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RASSF5 ( NM_182665.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_872606.1 Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu27551
Clone ID Related Accession (Same CDS sequence)	NM_182665.3 , NM_182665.4
Accession Version	NM_182665.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	ras association domain-containing protein 5 isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA370470.1, BC042651.1, BC004270.1 and CD367770.1. On Apr 24, 2014 this sequence version replaced NM_182665.2. Transcript Variant: This variant (3), also known as transcript B, differs in the 5' UTR, lacks a portion of the 5' coding region, and intiates translation at an alternate start codon, compared to variant 1. The resulting isoform (C), also known as NORE1B, is shorter and has a distinct N-terminus when compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF445801.1, BC042651.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCGTGG ACAGCAGCAT GAGCAGTGGG TACTGCAGCC TGGACGAGGA ACTGGAAGAC 
TGCTTCTTCA CTGCTAAGAC TACCTTTTTC AGAAATGCGC AGAGCAAACA TCTTTCAAAG 
AATGTCTGTA AACCTGTGGA GGAGACACAG CGCCCGCCCA CACTGCAGGA GATCAAGCAG 
AAGATCGACA GCTACAACAC GCGAGAGAAG AACTGCCTGG GCATGAAACT GAGTGAAGAC 
GGCACCTACA CGGGTTTCAT CAAAGTGCAT CTGAAACTCC GGCGGCCTGT GACGGTGCCT 
GCTGGGATCC GGCCCCAGTC CATCTATGAT GCCATCAAGG AGGTGAACCT GGCGGCTACC 
ACGGACAAGC GGACATCCTT CTACCTGCCC CTAGATGCCA TCAAGCAGCT GCACATCAGC 
AGCACCACCA CCGTCAGTGA GGTCATCCAG GGGCTGCTCA AGAAGTTCAT GGTTGTGGAC 
AATCCCCAGA AGTTTGCACT TTTTAAGCGG ATACACAAGG ACGGACAAGT GCTCTTCCAG 
AAACTCTCCA TTGCTGACCG CCCCCTCTAC CTGCGCCTGC TTGCTGGGCC TGACACGGAG 
GTCCTCAGCT TTGTGCTAAA GGAGAATGAA ACTGGAGAGG TAGAGTGGGA TGCCTTCTCC 
ATCCCTGAAC TTCAGAACTT CCTAACAATC CTGGAAAAAG AGGAGCAGGA CAAAATCCAA 
CAAGTGCAAA AGAAGTATGA CAAGTTTAGG CAGAAACTGG AGGAGGCCTT AAGAGAATCC 
CAGGGCAAAC CTGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872606.1
CDS	411..1208
Translation	MTVDSSMSSGYCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG

Target ORF information:

RefSeq Version	NM_182665.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182665.3

ORF Insert Sequence:

ATGACCGTGG ACAGCAGCAT GAGCAGTGGG TACTGCAGCC TGGACGAGGA ACTGGAAGAC 
TGCTTCTTCA CTGCTAAGAC TACCTTTTTC AGAAATGCGC AGAGCAAACA TCTTTCAAAG 
AATGTCTGTA AACCTGTGGA GGAGACACAG CGCCCGCCCA CACTGCAGGA GATCAAGCAG 
AAGATCGACA GCTACAACAC GCGAGAGAAG AACTGCCTGG GCATGAAACT GAGTGAAGAC 
GGCACCTACA CGGGTTTCAT CAAAGTGCAT CTGAAACTCC GGCGGCCTGT GACGGTGCCT 
GCTGGGATCC GGCCCCAGTC CATCTATGAT GCCATCAAGG AGGTGAACCT GGCGGCTACC 
ACGGACAAGC GGACATCCTT CTACCTGCCC CTAGATGCCA TCAAGCAGCT GCACATCAGC 
AGCACCACCA CCGTCAGTGA GGTCATCCAG GGGCTGCTCA AGAAGTTCAT GGTTGTGGAC 
AATCCCCAGA AGTTTGCACT TTTTAAGCGG ATACACAAGG ACGGACAAGT GCTCTTCCAG 
AAACTCTCCA TTGCTGACCG CCCCCTCTAC CTGCGCCTGC TTGCTGGGCC TGACACGGAG 
GTCCTCAGCT TTGTGCTAAA GGAGAATGAA ACTGGAGAGG TAGAGTGGGA TGCCTTCTCC 
ATCCCTGAAC TTCAGAACTT CCTAACAATC CTGGAAAAAG AGGAGCAGGA CAAAATCCAA 
CAAGTGCAAA AGAAGTATGA CAAGTTTAGG CAGAAACTGG AGGAGGCCTT AAGAGAATCC 
CAGGGCAAAC CTGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RASSF5 ( NM_182665.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_872606.1 Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu27551
Clone ID Related Accession (Same CDS sequence)	NM_182665.3 , NM_182665.4
Accession Version	NM_182665.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	ras association domain-containing protein 5 isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA370470.1, BC042651.1, BC004270.1, CD367770.1 and AC244034.4. On May 31, 2019 this sequence version replaced NM_182665.3. Transcript Variant: This variant (3), also known as transcript B, differs in the 5' UTR, lacks a portion of the 5' coding region, and intiates translation at an alternate start codon, compared to variant 1. The resulting isoform (C), also known as NORE1B, is shorter and has a distinct N-terminus when compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC042651.1, SRR1660803.84812.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCGTGG ACAGCAGCAT GAGCAGTGGG TACTGCAGCC TGGACGAGGA ACTGGAAGAC 
TGCTTCTTCA CTGCTAAGAC TACCTTTTTC AGAAATGCGC AGAGCAAACA TCTTTCAAAG 
AATGTCTGTA AACCTGTGGA GGAGACACAG CGCCCGCCCA CACTGCAGGA GATCAAGCAG 
AAGATCGACA GCTACAACAC GCGAGAGAAG AACTGCCTGG GCATGAAACT GAGTGAAGAC 
GGCACCTACA CGGGTTTCAT CAAAGTGCAT CTGAAACTCC GGCGGCCTGT GACGGTGCCT 
GCTGGGATCC GGCCCCAGTC CATCTATGAT GCCATCAAGG AGGTGAACCT GGCGGCTACC 
ACGGACAAGC GGACATCCTT CTACCTGCCC CTAGATGCCA TCAAGCAGCT GCACATCAGC 
AGCACCACCA CCGTCAGTGA GGTCATCCAG GGGCTGCTCA AGAAGTTCAT GGTTGTGGAC 
AATCCCCAGA AGTTTGCACT TTTTAAGCGG ATACACAAGG ACGGACAAGT GCTCTTCCAG 
AAACTCTCCA TTGCTGACCG CCCCCTCTAC CTGCGCCTGC TTGCTGGGCC TGACACGGAG 
GTCCTCAGCT TTGTGCTAAA GGAGAATGAA ACTGGAGAGG TAGAGTGGGA TGCCTTCTCC 
ATCCCTGAAC TTCAGAACTT CCTAACAATC CTGGAAAAAG AGGAGCAGGA CAAAATCCAA 
CAAGTGCAAA AGAAGTATGA CAAGTTTAGG CAGAAACTGG AGGAGGCCTT AAGAGAATCC 
CAGGGCAAAC CTGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872606.1
CDS	411..1208
Translation	MTVDSSMSSGYCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG

Target ORF information:

RefSeq Version	NM_182665.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182665.4

ORF Insert Sequence:

ATGACCGTGG ACAGCAGCAT GAGCAGTGGG TACTGCAGCC TGGACGAGGA ACTGGAAGAC 
TGCTTCTTCA CTGCTAAGAC TACCTTTTTC AGAAATGCGC AGAGCAAACA TCTTTCAAAG 
AATGTCTGTA AACCTGTGGA GGAGACACAG CGCCCGCCCA CACTGCAGGA GATCAAGCAG 
AAGATCGACA GCTACAACAC GCGAGAGAAG AACTGCCTGG GCATGAAACT GAGTGAAGAC 
GGCACCTACA CGGGTTTCAT CAAAGTGCAT CTGAAACTCC GGCGGCCTGT GACGGTGCCT 
GCTGGGATCC GGCCCCAGTC CATCTATGAT GCCATCAAGG AGGTGAACCT GGCGGCTACC 
ACGGACAAGC GGACATCCTT CTACCTGCCC CTAGATGCCA TCAAGCAGCT GCACATCAGC 
AGCACCACCA CCGTCAGTGA GGTCATCCAG GGGCTGCTCA AGAAGTTCAT GGTTGTGGAC 
AATCCCCAGA AGTTTGCACT TTTTAAGCGG ATACACAAGG ACGGACAAGT GCTCTTCCAG 
AAACTCTCCA TTGCTGACCG CCCCCTCTAC CTGCGCCTGC TTGCTGGGCC TGACACGGAG 
GTCCTCAGCT TTGTGCTAAA GGAGAATGAA ACTGGAGAGG TAGAGTGGGA TGCCTTCTCC 
ATCCCTGAAC TTCAGAACTT CCTAACAATC CTGGAAAAAG AGGAGCAGGA CAAAATCCAA 
CAAGTGCAAA AGAAGTATGA CAAGTTTAGG CAGAAACTGG AGGAGGCCTT AAGAGAATCC 
CAGGGCAAAC CTGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RASSF5 ( NM_182663.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_872604.1 Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28317
Clone ID Related Accession (Same CDS sequence)	NM_182663.3 , NM_182663.4
Accession Version	NM_182663.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	ras association domain-containing protein 5 isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289861.1, AK291268.1, BC004270.1 and CD367770.1. This sequence is a reference standard in the RefSeqGene project. On Apr 18, 2014 this sequence version replaced NM_182663.2. Transcript Variant: This variant (1), also known as transcript A, represents the longest transcript and encodes the longest isoform (A), also known as NORE1A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289861.1, SRR1803615.122634.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGG CGTCCCCGGC CATCGGGCAG CGCCCGTACC CGCTACTATT GGACCCCGAG 
CCGCCGCGCT ATCTACAGAG CCTGAGCGGC CCCGAGCTAC CGCCGCCGCC CCCCGACCGG 
TCCTCGCGCC TCTGTGTCCC GGCGCCCCTC TCCACTGCGC CCGGGGCGCG CGAGGGGCGC 
AGCGCCCGGA GGGCTGCCCG GGGGAACCTG GAGCCCCCGC CCCGGGCCTC CCGACCCGCT 
CGCCCGCTCC GGCCTGGTCT GCAGCAGAGA CTGCGGCGGC GGCCTGGAGC GCCCCGACCC 
CGCGACGTGC GGAGCATCTT CGAGCAGCCG CAGGATCCCA GAGTCCCGGC GGAGCGAGGC 
GAGGGGCACT GCTTCGCCGA GTTGGTGCTG CCGGGCGGCC CCGGCTGGTG TGACCTGTGC 
GGACGAGAGG TGCTGCGGCA GGCGCTGCGC TGCACTAACT GTAAATTCAC CTGTCACCCA 
GAATGCCGCA GCCTGATCCA GTTGGACTGC AGTCAGCAGG AGGGTTTATC CCGGGACAGA 
CCCTCTCCAG AAAGCACCCT CACCGTGACC TTCAGCCAGA ATGTCTGTAA ACCTGTGGAG 
GAGACACAGC GCCCGCCCAC ACTGCAGGAG ATCAAGCAGA AGATCGACAG CTACAACACG 
CGAGAGAAGA ACTGCCTGGG CATGAAACTG AGTGAAGACG GCACCTACAC GGGTTTCATC 
AAAGTGCATC TGAAACTCCG GCGGCCTGTG ACGGTGCCTG CTGGGATCCG GCCCCAGTCC 
ATCTATGATG CCATCAAGGA GGTGAACCTG GCGGCTACCA CGGACAAGCG GACATCCTTC 
TACCTGCCCC TAGATGCCAT CAAGCAGCTG CACATCAGCA GCACCACCAC CGTCAGTGAG 
GTCATCCAGG GGCTGCTCAA GAAGTTCATG GTTGTGGACA ATCCCCAGAA GTTTGCACTT 
TTTAAGCGGA TACACAAGGA CGGACAAGTG CTCTTCCAGA AACTCTCCAT TGCTGACCGC 
CCCCTCTACC TGCGCCTGCT TGCTGGGCCT GACACGGAGG TCCTCAGCTT TGTGCTAAAG 
GAGAATGAAA CTGGAGAGGT AGAGTGGGAT GCCTTCTCCA TCCCTGAACT TCAGAACTTC 
CTAACAATCC TGGAAAAAGA GGAGCAGGAC AAAATCCAAC AAGTGCAAAA GAAGTATGAC 
AAGTTTAGGC AGAAACTGGA GGAGGCCTTA AGAGAATCCC AGGGCAAACC TGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872604.1
CDS	74..1330
Translation	MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG

Target ORF information:

RefSeq Version	NM_182663.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182663.3

ORF Insert Sequence:

ATGGCCATGG CGTCCCCGGC CATCGGGCAG CGCCCGTACC CGCTACTATT GGACCCCGAG 
CCGCCGCGCT ATCTACAGAG CCTGAGCGGC CCCGAGCTAC CGCCGCCGCC CCCCGACCGG 
TCCTCGCGCC TCTGTGTCCC GGCGCCCCTC TCCACTGCGC CCGGGGCGCG CGAGGGGCGC 
AGCGCCCGGA GGGCTGCCCG GGGGAACCTG GAGCCCCCGC CCCGGGCCTC CCGACCCGCT 
CGCCCGCTCC GGCCTGGTCT GCAGCAGAGA CTGCGGCGGC GGCCTGGAGC GCCCCGACCC 
CGCGACGTGC GGAGCATCTT CGAGCAGCCG CAGGATCCCA GAGTCCCGGC GGAGCGAGGC 
GAGGGGCACT GCTTCGCCGA GTTGGTGCTG CCGGGCGGCC CCGGCTGGTG TGACCTGTGC 
GGACGAGAGG TGCTGCGGCA GGCGCTGCGC TGCACTAACT GTAAATTCAC CTGTCACCCA 
GAATGCCGCA GCCTGATCCA GTTGGACTGC AGTCAGCAGG AGGGTTTATC CCGGGACAGA 
CCCTCTCCAG AAAGCACCCT CACCGTGACC TTCAGCCAGA ATGTCTGTAA ACCTGTGGAG 
GAGACACAGC GCCCGCCCAC ACTGCAGGAG ATCAAGCAGA AGATCGACAG CTACAACACG 
CGAGAGAAGA ACTGCCTGGG CATGAAACTG AGTGAAGACG GCACCTACAC GGGTTTCATC 
AAAGTGCATC TGAAACTCCG GCGGCCTGTG ACGGTGCCTG CTGGGATCCG GCCCCAGTCC 
ATCTATGATG CCATCAAGGA GGTGAACCTG GCGGCTACCA CGGACAAGCG GACATCCTTC 
TACCTGCCCC TAGATGCCAT CAAGCAGCTG CACATCAGCA GCACCACCAC CGTCAGTGAG 
GTCATCCAGG GGCTGCTCAA GAAGTTCATG GTTGTGGACA ATCCCCAGAA GTTTGCACTT 
TTTAAGCGGA TACACAAGGA CGGACAAGTG CTCTTCCAGA AACTCTCCAT TGCTGACCGC 
CCCCTCTACC TGCGCCTGCT TGCTGGGCCT GACACGGAGG TCCTCAGCTT TGTGCTAAAG 
GAGAATGAAA CTGGAGAGGT AGAGTGGGAT GCCTTCTCCA TCCCTGAACT TCAGAACTTC 
CTAACAATCC TGGAAAAAGA GGAGCAGGAC AAAATCCAAC AAGTGCAAAA GAAGTATGAC 
AAGTTTAGGC AGAAACTGGA GGAGGCCTTA AGAGAATCCC AGGGCAAACC TGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RASSF5 ( NM_182663.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_872604.1 Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28317
Clone ID Related Accession (Same CDS sequence)	NM_182663.3 , NM_182663.4
Accession Version	NM_182663.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	ras association domain-containing protein 5 isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289861.1, AK291268.1, BC004270.1, CD367770.1 and AC244034.4. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_182663.3. Transcript Variant: This variant (1), also known as transcript A, represents the longest transcript and encodes the longest isoform (A), also known as NORE1A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.262070.1, SRR1803615.122634.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000579436.7/ ENSP00000462099.1 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGG CGTCCCCGGC CATCGGGCAG CGCCCGTACC CGCTACTATT GGACCCCGAG 
CCGCCGCGCT ATCTACAGAG CCTGAGCGGC CCCGAGCTAC CGCCGCCGCC CCCCGACCGG 
TCCTCGCGCC TCTGTGTCCC GGCGCCCCTC TCCACTGCGC CCGGGGCGCG CGAGGGGCGC 
AGCGCCCGGA GGGCTGCCCG GGGGAACCTG GAGCCCCCGC CCCGGGCCTC CCGACCCGCT 
CGCCCGCTCC GGCCTGGTCT GCAGCAGAGA CTGCGGCGGC GGCCTGGAGC GCCCCGACCC 
CGCGACGTGC GGAGCATCTT CGAGCAGCCG CAGGATCCCA GAGTCCCGGC GGAGCGAGGC 
GAGGGGCACT GCTTCGCCGA GTTGGTGCTG CCGGGCGGCC CCGGCTGGTG TGACCTGTGC 
GGACGAGAGG TGCTGCGGCA GGCGCTGCGC TGCACTAACT GTAAATTCAC CTGTCACCCA 
GAATGCCGCA GCCTGATCCA GTTGGACTGC AGTCAGCAGG AGGGTTTATC CCGGGACAGA 
CCCTCTCCAG AAAGCACCCT CACCGTGACC TTCAGCCAGA ATGTCTGTAA ACCTGTGGAG 
GAGACACAGC GCCCGCCCAC ACTGCAGGAG ATCAAGCAGA AGATCGACAG CTACAACACG 
CGAGAGAAGA ACTGCCTGGG CATGAAACTG AGTGAAGACG GCACCTACAC GGGTTTCATC 
AAAGTGCATC TGAAACTCCG GCGGCCTGTG ACGGTGCCTG CTGGGATCCG GCCCCAGTCC 
ATCTATGATG CCATCAAGGA GGTGAACCTG GCGGCTACCA CGGACAAGCG GACATCCTTC 
TACCTGCCCC TAGATGCCAT CAAGCAGCTG CACATCAGCA GCACCACCAC CGTCAGTGAG 
GTCATCCAGG GGCTGCTCAA GAAGTTCATG GTTGTGGACA ATCCCCAGAA GTTTGCACTT 
TTTAAGCGGA TACACAAGGA CGGACAAGTG CTCTTCCAGA AACTCTCCAT TGCTGACCGC 
CCCCTCTACC TGCGCCTGCT TGCTGGGCCT GACACGGAGG TCCTCAGCTT TGTGCTAAAG 
GAGAATGAAA CTGGAGAGGT AGAGTGGGAT GCCTTCTCCA TCCCTGAACT TCAGAACTTC 
CTAACAATCC TGGAAAAAGA GGAGCAGGAC AAAATCCAAC AAGTGCAAAA GAAGTATGAC 
AAGTTTAGGC AGAAACTGGA GGAGGCCTTA AGAGAATCCC AGGGCAAACC TGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872604.1
CDS	73..1329
Translation	MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG

Target ORF information:

RefSeq Version	NM_182663.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182663.4

ORF Insert Sequence:

ATGGCCATGG CGTCCCCGGC CATCGGGCAG CGCCCGTACC CGCTACTATT GGACCCCGAG 
CCGCCGCGCT ATCTACAGAG CCTGAGCGGC CCCGAGCTAC CGCCGCCGCC CCCCGACCGG 
TCCTCGCGCC TCTGTGTCCC GGCGCCCCTC TCCACTGCGC CCGGGGCGCG CGAGGGGCGC 
AGCGCCCGGA GGGCTGCCCG GGGGAACCTG GAGCCCCCGC CCCGGGCCTC CCGACCCGCT 
CGCCCGCTCC GGCCTGGTCT GCAGCAGAGA CTGCGGCGGC GGCCTGGAGC GCCCCGACCC 
CGCGACGTGC GGAGCATCTT CGAGCAGCCG CAGGATCCCA GAGTCCCGGC GGAGCGAGGC 
GAGGGGCACT GCTTCGCCGA GTTGGTGCTG CCGGGCGGCC CCGGCTGGTG TGACCTGTGC 
GGACGAGAGG TGCTGCGGCA GGCGCTGCGC TGCACTAACT GTAAATTCAC CTGTCACCCA 
GAATGCCGCA GCCTGATCCA GTTGGACTGC AGTCAGCAGG AGGGTTTATC CCGGGACAGA 
CCCTCTCCAG AAAGCACCCT CACCGTGACC TTCAGCCAGA ATGTCTGTAA ACCTGTGGAG 
GAGACACAGC GCCCGCCCAC ACTGCAGGAG ATCAAGCAGA AGATCGACAG CTACAACACG 
CGAGAGAAGA ACTGCCTGGG CATGAAACTG AGTGAAGACG GCACCTACAC GGGTTTCATC 
AAAGTGCATC TGAAACTCCG GCGGCCTGTG ACGGTGCCTG CTGGGATCCG GCCCCAGTCC 
ATCTATGATG CCATCAAGGA GGTGAACCTG GCGGCTACCA CGGACAAGCG GACATCCTTC 
TACCTGCCCC TAGATGCCAT CAAGCAGCTG CACATCAGCA GCACCACCAC CGTCAGTGAG 
GTCATCCAGG GGCTGCTCAA GAAGTTCATG GTTGTGGACA ATCCCCAGAA GTTTGCACTT 
TTTAAGCGGA TACACAAGGA CGGACAAGTG CTCTTCCAGA AACTCTCCAT TGCTGACCGC 
CCCCTCTACC TGCGCCTGCT TGCTGGGCCT GACACGGAGG TCCTCAGCTT TGTGCTAAAG 
GAGAATGAAA CTGGAGAGGT AGAGTGGGAT GCCTTCTCCA TCCCTGAACT TCAGAACTTC 
CTAACAATCC TGGAAAAAGA GGAGCAGGAC AAAATCCAAC AAGTGCAAAA GAAGTATGAC 
AAGTTTAGGC AGAAACTGGA GGAGGCCTTA AGAGAATCCC AGGGCAAACC TGGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RASSF5 ( NM_182664.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_872605.1 Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17011
Clone ID Related Accession (Same CDS sequence)	NM_182664.4 , NM_182664.3
Accession Version	NM_182664.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	ras association domain-containing protein 5 isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289861.1, AK291268.1, AY062003.1, BC004270.1, CD367770.1 and AC244034.4. On May 31, 2019 this sequence version replaced NM_182664.3. Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform B) is shorter and has a distinct C-terminus, compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY062003.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGG CGTCCCCGGC CATCGGGCAG CGCCCGTACC CGCTACTATT GGACCCCGAG 
CCGCCGCGCT ATCTACAGAG CCTGAGCGGC CCCGAGCTAC CGCCGCCGCC CCCCGACCGG 
TCCTCGCGCC TCTGTGTCCC GGCGCCCCTC TCCACTGCGC CCGGGGCGCG CGAGGGGCGC 
AGCGCCCGGA GGGCTGCCCG GGGGAACCTG GAGCCCCCGC CCCGGGCCTC CCGACCCGCT 
CGCCCGCTCC GGCCTGGTCT GCAGCAGAGA CTGCGGCGGC GGCCTGGAGC GCCCCGACCC 
CGCGACGTGC GGAGCATCTT CGAGCAGCCG CAGGATCCCA GAGTCCCGGC GGAGCGAGGC 
GAGGGGCACT GCTTCGCCGA GTTGGTGCTG CCGGGCGGCC CCGGCTGGTG TGACCTGTGC 
GGACGAGAGG TGCTGCGGCA GGCGCTGCGC TGCACTAACT GTAAATTCAC CTGTCACCCA 
GAATGCCGCA GCCTGATCCA GTTGGACTGC AGTCAGCAGG AGGGTTTATC CCGGGACAGA 
CCCTCTCCAG AAAGCACCCT CACCGTGACC TTCAGCCAGA ATGTCTGTAA ACCTGTGGAG 
GAGACACAGC GCCCGCCCAC ACTGCAGGAG ATCAAGCAGA AGATCGACAG CTACAACACG 
CGAGAGAAGA ACTGCCTGGG CATGAAACTG AGTGAAGACG GCACCTACAC GGGTTTCATC 
AAAGTGCATC TGAAACTCCG GCGGCCTGTG ACGGTGCCTG CTGGGATCCG GCCCCAGTCC 
ATCTATGATG CCATCAAGGA GGTGAACCTG GCGGCTACCA CGGACAAGCG GACATCCTTC 
TACCTGCCCC TAGATGCCAT CAAGCAGCTG CACATCAGCA GCACCACCAC CGTCAGTGAG 
GTCATCCAGG GGCTGCTCAA GAAGTTCATG GTTGTGGACA ATCCCCAGAA GTTTGCACTT 
TTTAAGCGGA TACACAAGGA CGGACAAGTG GGATGCCTTC TCCATCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872605.1
CDS	73..1083
Translation	MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP

Target ORF information:

RefSeq Version	NM_182664.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182664.4

ORF Insert Sequence:

ATGGCCATGG CGTCCCCGGC CATCGGGCAG CGCCCGTACC CGCTACTATT GGACCCCGAG 
CCGCCGCGCT ATCTACAGAG CCTGAGCGGC CCCGAGCTAC CGCCGCCGCC CCCCGACCGG 
TCCTCGCGCC TCTGTGTCCC GGCGCCCCTC TCCACTGCGC CCGGGGCGCG CGAGGGGCGC 
AGCGCCCGGA GGGCTGCCCG GGGGAACCTG GAGCCCCCGC CCCGGGCCTC CCGACCCGCT 
CGCCCGCTCC GGCCTGGTCT GCAGCAGAGA CTGCGGCGGC GGCCTGGAGC GCCCCGACCC 
CGCGACGTGC GGAGCATCTT CGAGCAGCCG CAGGATCCCA GAGTCCCGGC GGAGCGAGGC 
GAGGGGCACT GCTTCGCCGA GTTGGTGCTG CCGGGCGGCC CCGGCTGGTG TGACCTGTGC 
GGACGAGAGG TGCTGCGGCA GGCGCTGCGC TGCACTAACT GTAAATTCAC CTGTCACCCA 
GAATGCCGCA GCCTGATCCA GTTGGACTGC AGTCAGCAGG AGGGTTTATC CCGGGACAGA 
CCCTCTCCAG AAAGCACCCT CACCGTGACC TTCAGCCAGA ATGTCTGTAA ACCTGTGGAG 
GAGACACAGC GCCCGCCCAC ACTGCAGGAG ATCAAGCAGA AGATCGACAG CTACAACACG 
CGAGAGAAGA ACTGCCTGGG CATGAAACTG AGTGAAGACG GCACCTACAC GGGTTTCATC 
AAAGTGCATC TGAAACTCCG GCGGCCTGTG ACGGTGCCTG CTGGGATCCG GCCCCAGTCC 
ATCTATGATG CCATCAAGGA GGTGAACCTG GCGGCTACCA CGGACAAGCG GACATCCTTC 
TACCTGCCCC TAGATGCCAT CAAGCAGCTG CACATCAGCA GCACCACCAC CGTCAGTGAG 
GTCATCCAGG GGCTGCTCAA GAAGTTCATG GTTGTGGACA ATCCCCAGAA GTTTGCACTT 
TTTAAGCGGA TACACAAGGA CGGACAAGTG GGATGCCTTC TCCATCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RASSF5 ( NM_182664.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_872605.1 Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17011
Clone ID Related Accession (Same CDS sequence)	NM_182664.4 , NM_182664.3
Accession Version	NM_182664.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	ras association domain-containing protein 5 isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK289861.1, AK291268.1, AY062003.1, BC004270.1 and CD367770.1. On Apr 24, 2014 this sequence version replaced NM_182664.2. Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform B) is shorter and has a distinct C-terminus, compared to isoform A. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY062003.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGG CGTCCCCGGC CATCGGGCAG CGCCCGTACC CGCTACTATT GGACCCCGAG 
CCGCCGCGCT ATCTACAGAG CCTGAGCGGC CCCGAGCTAC CGCCGCCGCC CCCCGACCGG 
TCCTCGCGCC TCTGTGTCCC GGCGCCCCTC TCCACTGCGC CCGGGGCGCG CGAGGGGCGC 
AGCGCCCGGA GGGCTGCCCG GGGGAACCTG GAGCCCCCGC CCCGGGCCTC CCGACCCGCT 
CGCCCGCTCC GGCCTGGTCT GCAGCAGAGA CTGCGGCGGC GGCCTGGAGC GCCCCGACCC 
CGCGACGTGC GGAGCATCTT CGAGCAGCCG CAGGATCCCA GAGTCCCGGC GGAGCGAGGC 
GAGGGGCACT GCTTCGCCGA GTTGGTGCTG CCGGGCGGCC CCGGCTGGTG TGACCTGTGC 
GGACGAGAGG TGCTGCGGCA GGCGCTGCGC TGCACTAACT GTAAATTCAC CTGTCACCCA 
GAATGCCGCA GCCTGATCCA GTTGGACTGC AGTCAGCAGG AGGGTTTATC CCGGGACAGA 
CCCTCTCCAG AAAGCACCCT CACCGTGACC TTCAGCCAGA ATGTCTGTAA ACCTGTGGAG 
GAGACACAGC GCCCGCCCAC ACTGCAGGAG ATCAAGCAGA AGATCGACAG CTACAACACG 
CGAGAGAAGA ACTGCCTGGG CATGAAACTG AGTGAAGACG GCACCTACAC GGGTTTCATC 
AAAGTGCATC TGAAACTCCG GCGGCCTGTG ACGGTGCCTG CTGGGATCCG GCCCCAGTCC 
ATCTATGATG CCATCAAGGA GGTGAACCTG GCGGCTACCA CGGACAAGCG GACATCCTTC 
TACCTGCCCC TAGATGCCAT CAAGCAGCTG CACATCAGCA GCACCACCAC CGTCAGTGAG 
GTCATCCAGG GGCTGCTCAA GAAGTTCATG GTTGTGGACA ATCCCCAGAA GTTTGCACTT 
TTTAAGCGGA TACACAAGGA CGGACAAGTG GGATGCCTTC TCCATCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872605.1
CDS	74..1084
Translation	MAMASPAIGQRPYPLLLDPEPPRYLQSLSGPELPPPPPDRSSRLCVPAPLSTAPGAREGRSARRAARGNLEPPPRASRPARPLRPGLQQRLRRRPGAPRPRDVRSIFEQPQDPRVPAERGEGHCFAELVLPGGPGWCDLCGREVLRQALRCTNCKFTCHPECRSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP

Target ORF information:

RefSeq Version	NM_182664.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras association domain family member 5 (RASSF5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182664.3

ORF Insert Sequence:

ATGGCCATGG CGTCCCCGGC CATCGGGCAG CGCCCGTACC CGCTACTATT GGACCCCGAG 
CCGCCGCGCT ATCTACAGAG CCTGAGCGGC CCCGAGCTAC CGCCGCCGCC CCCCGACCGG 
TCCTCGCGCC TCTGTGTCCC GGCGCCCCTC TCCACTGCGC CCGGGGCGCG CGAGGGGCGC 
AGCGCCCGGA GGGCTGCCCG GGGGAACCTG GAGCCCCCGC CCCGGGCCTC CCGACCCGCT 
CGCCCGCTCC GGCCTGGTCT GCAGCAGAGA CTGCGGCGGC GGCCTGGAGC GCCCCGACCC 
CGCGACGTGC GGAGCATCTT CGAGCAGCCG CAGGATCCCA GAGTCCCGGC GGAGCGAGGC 
GAGGGGCACT GCTTCGCCGA GTTGGTGCTG CCGGGCGGCC CCGGCTGGTG TGACCTGTGC 
GGACGAGAGG TGCTGCGGCA GGCGCTGCGC TGCACTAACT GTAAATTCAC CTGTCACCCA 
GAATGCCGCA GCCTGATCCA GTTGGACTGC AGTCAGCAGG AGGGTTTATC CCGGGACAGA 
CCCTCTCCAG AAAGCACCCT CACCGTGACC TTCAGCCAGA ATGTCTGTAA ACCTGTGGAG 
GAGACACAGC GCCCGCCCAC ACTGCAGGAG ATCAAGCAGA AGATCGACAG CTACAACACG 
CGAGAGAAGA ACTGCCTGGG CATGAAACTG AGTGAAGACG GCACCTACAC GGGTTTCATC 
AAAGTGCATC TGAAACTCCG GCGGCCTGTG ACGGTGCCTG CTGGGATCCG GCCCCAGTCC 
ATCTATGATG CCATCAAGGA GGTGAACCTG GCGGCTACCA CGGACAAGCG GACATCCTTC 
TACCTGCCCC TAGATGCCAT CAAGCAGCTG CACATCAGCA GCACCACCAC CGTCAGTGAG 
GTCATCCAGG GGCTGCTCAA GAAGTTCATG GTTGTGGACA ATCCCCAGAA GTTTGCACTT 
TTTAAGCGGA TACACAAGGA CGGACAAGTG GGATGCCTTC TCCATCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ubc9 Binds to ADAP and Is Required for Rap1 Membrane Recruitment, Rac1 Activation, and Integrin-Mediated T Cell Adhesion.
Journal of immunology (Baltimore, Md. : 1950)199(12)4142-4154(2017 Dec)
Xiong Y,Ye C,Yang N,Li M,Liu H

Nonstructural protein 5B promotes degradation of the NORE1A tumor suppressor to facilitate hepatitis C virus replication.
Hepatology (Baltimore, Md.)65(5)1462-1477(2017 05)
Arora P,Basu A,Schmidt ML,Clark GJ,Donninger H,Nichols DB,Calvisi DF,Kaushik-Basu N

The emerging roles of RASSF5 in human malignancy.
Anti-cancer agents in medicinal chemistry(2017 Mar)
Li S,Teng J,Li H,Zheng J,Chen F

MiR-214 regulates oral cancer KB cell apoptosis through targeting RASSF5.
Genetics and molecular research : GMR16(1)(2017 Mar)
Li TK,Yin K,Chen Z,Bao Y,Zhang SX

NORE1A induction by membrane-bound CD40L (mCD40L) contributes to CD40L-induced cell death and G1 growth arrest in p21-mediated mechanism.
Cell death & disease7e2146(2016 Mar)
Elmetwali T,Salman A,Palmer DH

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RASSF5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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