Stat4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Stat4
Entrez Gene ID	367264
Full Name	signal transducer and activator of transcription 4
General protein information	Preferred Names signal transducer and activator of transcription 4 Names signal transducer and activator of transcription 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012226.1	NP_001012226.1	signal transducer and activator of transcription 4

Pathways from BioSystems

Homologies

Homo sapiens (human)	STAT4	NP_001230764.1
Xenopus tropicalis (tropical clawed frog)	stat4	XP_002937488.2
Pan troglodytes (chimpanzee)	STAT4	XP_003309420.1
Mus musculus (house mouse)	Stat4	NP_035617.1
	STAT4	XP_002799067.1
Canis lupus familiaris (dog)	STAT4	XP_005640526.1
Bos taurus (cattle)	STAT4	NP_001077161.2
Danio rerio (zebrafish)	stat4	NP_001004510.1
Gallus gallus (chicken)	STAT4	NP_001254484.1
Rattus norvegicus (Norway rat)	Stat4	NP_001012226.1

Gene Ontology
Bibliography

Related articles in PubMed

Jak-Stat signaling pathway may play a role in the pathogenesis of cholesteatoma.
Eskiizmir G, Seda Vatansever H, Ozg?r E, Aslan A, Tanyeri G, G?z?a??k D, Kemal ?zbilgin M, Cingi C
American journal of otolaryngology35(2)130-6(2014 Mar-Apr)

STAT4 is critical for immunity but not for antileishmanial activity of antimonials in experimental visceral leishmaniasis.
Oghumu S, Gupta G, Snider HM, Varikuti S, Terrazas CA, Papenfuss TL, Kaplan MH, Satoskar AR
European journal of immunology44(2)450-9(2014 Feb)

Association between a C8orf13-BLK polymorphism and polymyositis/dermatomyositis in the Japanese population: an additive effect with STAT4 on disease susceptibility.
Sugiura T, Kawaguchi Y, Goto K, Hayashi Y, Gono T, Furuya T, Nishino I, Yamanaka H
PloS one9(3)e90019(2014)

[Relationship of reduced lung function with Th1/Th2 polarization, STAT4/6 expression in rats of chronic obstructive pulmonary disease].
Wang C, Li Z
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology29(12)1233-6(2013 Dec)

Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation.
Pham D, Yu Q, Walline CC, Muthukrishnan R, Blum JS, Kaplan MH
Journal of immunology (Baltimore, Md. : 1950)191(2)902-11(2013 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Stat4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Stat4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02779	NM_001012226.1 Latest version!	Rattus norvegicus signal transducer and activator of transcription 4 (Stat4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$440.30 $629.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Stat4 ( NM_001012226.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012226.1 Rattus norvegicus signal transducer and activator of transcription 4 (Stat4), mRNA.

Price & Availability↑

CloneID	ORa02779
Clone ID Related Accession (Same CDS sequence)	NM_001012226.1
Accession Version	NM_001012226.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2247bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	signal transducer and activator of transcription 4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081938.1. On Feb 11, 2005 this sequence version replaced XM_346046.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC081938.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052297, SAMEA2689594 [ECO:0000350] ##Evidence-Data-END##

ATGTCTCAGT GGAATCAAGT CCAACAATTA GAAATCAAGT TTTTGGAGCA AGTAGATCAG 
TTCTATGATG ACAACTTTCC TATGGAAATC CGGCATCTGC TGGCCCAGTG GATTGAGACT 
CAAGACTGGG AAGTAGCTTC TAACAATGAA ACTATGGCAA CAATTCTCCT TCAAAACTTA 
TTAATACAAT TGGATGAACA GTTAGGTCGG GTTTCCAAAG AGAAAAACCT GCTATTGATT 
CACAATCTAA AGAGAATTAG GAAAGTTCTT CAGGGAAAGT TTCACGGAAA TCCAATGCAT 
GTAGCTGTGG TCATTTCAAA TTGCTTAAGG GAAGAGAGGA GAATACTGGC TGCGGCCAAC 
ATGCCTATCC AGGGACCTCT GGAGAAATCT TTACAGAGCT CTTCAGTTTC AGAAAGACAG 
AGAAATGTGG AACACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAC 
ACCAAATACT TAGAAGATCT GCAAGATGAG TTTGACTACA GGTATAAAAC AATTCAGACA 
ATGGATCAGG GTGACAAGAA CAGTATCCTG GTGAACCAGG AAGTTTTGAC ATTGCAAGAA 
ATGCTTAATA ACCTGGACTT TAAAAGAAAG GAAGCACTCA GTAAGATGAC ACAGATAGTG 
AATGAGACAG ACCTGCTCAT GAACAGCATG CTGCTAGAAG AGCTGCAGGA CTGGAAGAAG 
CGGCAACAGA TCGCCTGCAT TGGTGGCCCG CTCCACAACG GGTTGGACCA GCTTCAGAAC 
TGCTTTACCC TACTGGCAGA GAGTCTTTTC CAACTTAGAC AGCAACTGGA GAAATTACAG 
GAGCAATCTA CCAAAATGAC GTACGAAGGG GATCCCATCC CTGCTCAAAG AGTTCACCTG 
CTGGAGAGAG CGACCTTCCT CATCTACAAC CTTTTTAAGA ATTCATTTGT GGTCGAGCGA 
CAGCCATGCA TGCCAACACA CCCTCAGAGG CCGATGGTAC TTAAAACCCT CATTCAGTTC 
ACTGTAAAAT TGAGATTACT AATAAAATTG CCAGAACTGA ACTATCAGGT GAAAGTGAAG 
GCATCCATTG ACAAGAATGT CTCAACTCTA AGCAATAGAA GATTTGTGCT CTGTGGAACT 
CACATCAAAG CTATGTCCAG TGAGGAATCT TCCAATGGGA GCCTCTCAGT GGAGTTTAGA 
CATTTGCAAC CGAAGGAGAT GAAGTGCAGC ACTGGGAGTA AAGGAAACGA GGGCTGCCAC 
ATGGTGACGG AAGAGCTGCA CTCCATAACC TTTGAGACCC AGATCTGCCT CTATGGCCTC 
ACCATTAACC TAGAGACCAG CTCATTACCT GTGGTGATGA TTTCTAATGT CAGCCAACTC 
CCTAATGCAT GGGCGTCCAT CATTTGGTAC AATGTGTCAA CCAACGACTC CCAGAACTTG 
GTTTTCTTTA ACAACCCTCC ATCTGTTACC TTGGGCCAAC TCCTGGAAGT GATGAGCTGG 
CAGTTTTCAT CCTACGTCGG TCGTGGCCTT AATTCAGACC AGCTCAACAT GCTGGCAGAG 
AAGCTCACAG TTCAGTCTAA CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG 
GAACATTTGC CTGGCAAAAC GTTTACCTTC TGGACCTGGC TTGAAGCAAT ATTGGACCTA 
ATTAAAAAAC ACATTCTTCC CCTCTGGATT GATGGGTACA TCATGGGCTT TGTTAGCAAA 
GAGAAGGAAC GGCTTCTGCT CAAAGATAAA ATGCCTGGGA CATTTTTGTT AAGATTCAGT 
GAGAGCCATC TTGGAGGGAT AACCTTCACC TGGGTGGACC AATCTGAAAA TGGAGAAGTG 
AGATTCCACT CCGTGGAACC CTACAACAAA GCGCGGCTAT CAGCTCTGCC ATTCGCTGAC 
ATTCTTCGAG ACTACAAGGT TATCATGGCT GAAAACATCC CCGAAAACCC TCTGAAGTAC 
CTCTACCCTG ACATTCCCAA AGACAAAGCC TTTGGCAAAC ACTACAGCTC CCAGCCGTGC 
GAAGTTTCAA GACCGACAGA ACGGGGCGAC AAGGGTTATG TCCCCTCTGT TTTTATACCC 
ATTTCAACAA TCCGAAGTGA TTCCACGGAG CCACAGTCTC CTTCAGACCT TCTCCCCATG 
TCACCAAGTG CATATGCTGT GCTGAGAGAA AACCTGAGCC CAACGACAAT TGAGACTGCA 
ATGAATTCCC CGTATTCTGC TGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012226.1
CDS	474..2720
Translation	MSQWNQVQQLEIKFLEQVDQFYDDNFPMEIRHLLAQWIETQDWEVASNNETMATILLQNLLIQLDEQLGRVSKEKNLLLIHNLKRIRKVLQGKFHGNPMHVAVVISNCLREERRILAAANMPIQGPLEKSLQSSSVSERQRNVEHKVAAIKNSVQMTEQDTKYLEDLQDEFDYRYKTIQTMDQGDKNSILVNQEVLTLQEMLNNLDFKRKEALSKMTQIVNETDLLMNSMLLEELQDWKKRQQIACIGGPLHNGLDQLQNCFTLLAESLFQLRQQLEKLQEQSTKMTYEGDPIPAQRVHLLERATFLIYNLFKNSFVVERQPCMPTHPQRPMVLKTLIQFTVKLRLLIKLPELNYQVKVKASIDKNVSTLSNRRFVLCGTHIKAMSSEESSNGSLSVEFRHLQPKEMKCSTGSKGNEGCHMVTEELHSITFETQICLYGLTINLETSSLPVVMISNVSQLPNAWASIIWYNVSTNDSQNLVFFNNPPSVTLGQLLEVMSWQFSSYVGRGLNSDQLNMLAEKLTVQSNYSDGHLTWAKFCKEHLPGKTFTFWTWLEAILDLIKKHILPLWIDGYIMGFVSKEKERLLLKDKMPGTFLLRFSESHLGGITFTWVDQSENGEVRFHSVEPYNKARLSALPFADILRDYKVIMAENIPENPLKYLYPDIPKDKAFGKHYSSQPCEVSRPTERGDKGYVPSVFIPISTIRSDSTEPQSPSDLLPMSPSAYAVLRENLSPTTIETAMNSPYSAE

Target ORF information:

RefSeq Version	NM_001012226.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal transducer and activator of transcription 4 (Stat4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012226.1

ORF Insert Sequence:

ATGTCTCAGT GGAATCAAGT CCAACAATTA GAAATCAAGT TTTTGGAGCA AGTAGATCAG 
TTCTATGATG ACAACTTTCC TATGGAAATC CGGCATCTGC TGGCCCAGTG GATTGAGACT 
CAAGACTGGG AAGTAGCTTC TAACAATGAA ACTATGGCAA CAATTCTCCT TCAAAACTTA 
TTAATACAAT TGGATGAACA GTTAGGTCGG GTTTCCAAAG AGAAAAACCT GCTATTGATT 
CACAATCTAA AGAGAATTAG GAAAGTTCTT CAGGGAAAGT TTCACGGAAA TCCAATGCAT 
GTAGCTGTGG TCATTTCAAA TTGCTTAAGG GAAGAGAGGA GAATACTGGC TGCGGCCAAC 
ATGCCTATCC AGGGACCTCT GGAGAAATCT TTACAGAGCT CTTCAGTTTC AGAAAGACAG 
AGAAATGTGG AACACAAAGT GGCTGCCATT AAAAACAGTG TGCAGATGAC AGAACAAGAC 
ACCAAATACT TAGAAGATCT GCAAGATGAG TTTGACTACA GGTATAAAAC AATTCAGACA 
ATGGATCAGG GTGACAAGAA CAGTATCCTG GTGAACCAGG AAGTTTTGAC ATTGCAAGAA 
ATGCTTAATA ACCTGGACTT TAAAAGAAAG GAAGCACTCA GTAAGATGAC ACAGATAGTG 
AATGAGACAG ACCTGCTCAT GAACAGCATG CTGCTAGAAG AGCTGCAGGA CTGGAAGAAG 
CGGCAACAGA TCGCCTGCAT TGGTGGCCCG CTCCACAACG GGTTGGACCA GCTTCAGAAC 
TGCTTTACCC TACTGGCAGA GAGTCTTTTC CAACTTAGAC AGCAACTGGA GAAATTACAG 
GAGCAATCTA CCAAAATGAC GTACGAAGGG GATCCCATCC CTGCTCAAAG AGTTCACCTG 
CTGGAGAGAG CGACCTTCCT CATCTACAAC CTTTTTAAGA ATTCATTTGT GGTCGAGCGA 
CAGCCATGCA TGCCAACACA CCCTCAGAGG CCGATGGTAC TTAAAACCCT CATTCAGTTC 
ACTGTAAAAT TGAGATTACT AATAAAATTG CCAGAACTGA ACTATCAGGT GAAAGTGAAG 
GCATCCATTG ACAAGAATGT CTCAACTCTA AGCAATAGAA GATTTGTGCT CTGTGGAACT 
CACATCAAAG CTATGTCCAG TGAGGAATCT TCCAATGGGA GCCTCTCAGT GGAGTTTAGA 
CATTTGCAAC CGAAGGAGAT GAAGTGCAGC ACTGGGAGTA AAGGAAACGA GGGCTGCCAC 
ATGGTGACGG AAGAGCTGCA CTCCATAACC TTTGAGACCC AGATCTGCCT CTATGGCCTC 
ACCATTAACC TAGAGACCAG CTCATTACCT GTGGTGATGA TTTCTAATGT CAGCCAACTC 
CCTAATGCAT GGGCGTCCAT CATTTGGTAC AATGTGTCAA CCAACGACTC CCAGAACTTG 
GTTTTCTTTA ACAACCCTCC ATCTGTTACC TTGGGCCAAC TCCTGGAAGT GATGAGCTGG 
CAGTTTTCAT CCTACGTCGG TCGTGGCCTT AATTCAGACC AGCTCAACAT GCTGGCAGAG 
AAGCTCACAG TTCAGTCTAA CTACAGTGAT GGTCACCTCA CCTGGGCCAA GTTCTGCAAG 
GAACATTTGC CTGGCAAAAC GTTTACCTTC TGGACCTGGC TTGAAGCAAT ATTGGACCTA 
ATTAAAAAAC ACATTCTTCC CCTCTGGATT GATGGGTACA TCATGGGCTT TGTTAGCAAA 
GAGAAGGAAC GGCTTCTGCT CAAAGATAAA ATGCCTGGGA CATTTTTGTT AAGATTCAGT 
GAGAGCCATC TTGGAGGGAT AACCTTCACC TGGGTGGACC AATCTGAAAA TGGAGAAGTG 
AGATTCCACT CCGTGGAACC CTACAACAAA GCGCGGCTAT CAGCTCTGCC ATTCGCTGAC 
ATTCTTCGAG ACTACAAGGT TATCATGGCT GAAAACATCC CCGAAAACCC TCTGAAGTAC 
CTCTACCCTG ACATTCCCAA AGACAAAGCC TTTGGCAAAC ACTACAGCTC CCAGCCGTGC 
GAAGTTTCAA GACCGACAGA ACGGGGCGAC AAGGGTTATG TCCCCTCTGT TTTTATACCC 
ATTTCAACAA TCCGAAGTGA TTCCACGGAG CCACAGTCTC CTTCAGACCT TCTCCCCATG 
TCACCAAGTG CATATGCTGT GCTGAGAGAA AACCTGAGCC CAACGACAAT TGAGACTGCA 
ATGAATTCCC CGTATTCTGC TGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Jak-Stat signaling pathway may play a role in the pathogenesis of cholesteatoma.
American journal of otolaryngology35(2)130-6(2014 Mar-Apr)
Eskiizmir G,Seda Vatansever H,Ozg?r E,Aslan A,Tanyeri G,G?z?a??k D,Kemal ?zbilgin M,Cingi C

STAT4 is critical for immunity but not for antileishmanial activity of antimonials in experimental visceral leishmaniasis.
European journal of immunology44(2)450-9(2014 Feb)
Oghumu S,Gupta G,Snider HM,Varikuti S,Terrazas CA,Papenfuss TL,Kaplan MH,Satoskar AR

Association between a C8orf13-BLK polymorphism and polymyositis/dermatomyositis in the Japanese population: an additive effect with STAT4 on disease susceptibility.
PloS one9(3)e90019(2014)
Sugiura T,Kawaguchi Y,Goto K,Hayashi Y,Gono T,Furuya T,Nishino I,Yamanaka H

[Relationship of reduced lung function with Th1/Th2 polarization, STAT4/6 expression in rats of chronic obstructive pulmonary disease].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology29(12)1233-6(2013 Dec)
Wang C,Li Z

Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation.
Journal of immunology (Baltimore, Md. : 1950)191(2)902-11(2013 Jul)
Pham D,Yu Q,Walline CC,Muthukrishnan R,Blum JS,Kaplan MH

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Stat4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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