Nono cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nono
Entrez Gene ID	317259
Full Name	non-POU domain containing, octamer-binding
General protein information	Preferred Names non-POU domain containing, octamer-binding Names non-POU domain-containing octamer-binding protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012356.1	NP_001012356.1	non-POU domain-containing octamer-binding protein

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Nono	NP_001239447.1
Gallus gallus (chicken)	NONO	NP_001026703.1
Pan troglodytes (chimpanzee)	NONO	XP_001136666.1
Canis lupus familiaris (dog)	NONO	XP_005641524.1
Rattus norvegicus (Norway rat)	Nono	NP_001012356.1
Danio rerio (zebrafish)	nono	NP_963873.1
Homo sapiens (human)	NONO	NP_031389.3
	NONO	XP_001091069.1
Bos taurus (cattle)	NONO	NP_001040019.1
Xenopus tropicalis (tropical clawed frog)	nono	NP_991398.1

Gene Ontology
Bibliography

Related articles in PubMed

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response.
Morchikh M, Cribier A, Raffel R, Amraoui S, Cau J, Severac D, Dubois E, Schwartz O, Bennasser Y, Benkirane M
Molecular cell67(3)387-399.e5(2017 Aug)

Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.
Sury MD, McShane E, Hernandez-Miranda LR, Birchmeier C, Selbach M
Molecular & cellular proteomics : MCP14(1)50-65(2015 Jan)

Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.
Wallach T, Schellenberg K, Maier B, Kalathur RK, Porras P, Wanker EE, Futschik ME, Kramer A
PLoS genetics9(3)e1003398(2013 Mar)

Distinct roles of DBHS family members in the circadian transcriptional feedback loop.
Kowalska E, Ripperger JA, Muheim C, Maier B, Kurihara Y, Fox AH, Kramer A, Brown SA
Molecular and cellular biology32(22)4585-94(2012 Nov)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Quantitative proteomics reveals dynamic interaction of JNK with RNA transport granule proteins Sfpq and Nono during neuronal differentiation
Title: Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.

NONO and SFPQ were functionally involved in circadian Prl transcription since overexpression of both proteins greatly reduced Prl promoter activity (P<0.001) and disrupted its circadian pattern.
Title: Chromatin remodeling as a mechanism for circadian prolactin transcription: rhythmic NONO and SFPQ recruitment to HLTF.

The following Nono gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nono cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02871	NM_001012356.1 Latest version!	Rattus norvegicus non-POU domain containing, octamer-binding (Nono), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$279.30 $399.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nono ( NM_001012356.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001012356.1 Rattus norvegicus non-POU domain containing, octamer-binding (Nono), mRNA.

Price & Availability↑

CloneID	ORa02871
Clone ID Related Accession (Same CDS sequence)	NM_001012356.1
Accession Version	NM_001012356.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Rattus norvegicus(Norway rat)
Product	non-POU domain-containing octamer-binding protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC089880.1. On Feb 18, 2005 this sequence version replaced XM_228554.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC089880.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCAGAGCA ATAAAACCTT TAACTTGGAG AAGCAGAATC ATACTCCAAG GAAGCACCAT 
CAGCATCACC ACCAGCAGCA CCATCAGCAA CAGCAGCAGC AGCAGCAGCA GCAGCAGCAG 
CAGCCACCCC CACCAATACC TGCAAATGGA CAGCAGGCCA GCAGCCAGAA TGAAGGCTTG 
ACTATTGACC TGAAGAATTT TAGGAAACCA GGAGAGAAGA CCTTTACCCA ACGTAGCCGT 
CTCTTTGTGG GCAATCTTCC CCCTGACATC ACTGAGGAGG AAATGAGGAA ACTTTTTGAG 
AAATATGGGA AAGCAGGCGA AGTTTTCATT CATAAGGATA AAGGCTTTGG CTTTATTCGC 
TTGGAAACAC GAACCCTAGC GGAAATTGCC AAAGTGGAGC TGGACAACAT GCCACTCCGT 
GGAAAGCAGC TGCGAGTGCG CTTTGCTTGT CATAGTGCAT CCCTTACGGT TCGCAACCTT 
CCTCAGTACG TGTCCAACGA ACTGCTGGAA GAAGCCTTTT CTGTGTTTGG CCAGGTGGAG 
AGGGCTGTAG TCATTGTGGA TGACCGAGGA AGGCCCTCGG GGAAAGGCAT TGTTGAGTTC 
TCAGGGAAGC CAGCTGCTCG GAAAGCTCTG GACAGATGCA GTGAAGGCTC CTTCTTGCTA 
ACCACATTTC CTCGGCCTGT GACTGTGGAG CCTATGGACC AGTTAGATGA TGAAGAGGGA 
CTTCCGGAGA AGTTGGTTAT AAAAAACCAG CAATTTCACA AGGAGAGAGA ACAGCCACCC 
AGATTTGCAC AGCCTGGGTC CTTTGAGTAT GAGTATGCCA TGCGCTGGAA GGCTCTCATT 
GAGATGGAGA AGCAACAGCA GGATCAAGTG GACCGAAACA TCAAGGAGGC TCGTGAGAAG 
CTGGAGATGG AGATGGAGGC AGCACGCCAT GAGCACCAGG TTATGCTAAT GAGGCAGGAT 
TTGATGAGAC GTCAAGAAGA GCTTCGAAGA ATGGAGGAGC TGCATAACCA AGAGGTTCAG 
AAACGAAAGC AGTTAGAACT CAGGCAGGAA GAGGAACGCA GGCGCCGTGA GGAAGAGATG 
CGGCGACAGC AAGAAGAAAT GATGCGACGG CAGCAGGAAG GATTCAAGGG AACCTTCCCT 
GATGCGAGAG AACAAGAGAT ACGGATGGGC CAAATGGCTA TGGGAGGTGC CATGGGCATA 
AACAATAGAG GCGCCATGCC CCCTGCTCCT GTGCCACCTG GTACTCCAGC TCCTCCAGGA 
CCTGCTGCTA TGATGCCAGA TGGAACCCTT GGATTGACTC CACCAACAAC TGAACGTTTT 
GGCCAAGCTG CTACAATGGA AGGAATTGGA GCAATTGGTG GAACTCCTCC TGCATTCAAC 
CGTCCAGCTC CTGGAGCTGA ATTTGCTCCA AATAAACGCC GCCGATATTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012356.1
CDS	125..1555
Translation	MQSNKTFNLEKQNHTPRKHHQHHHQQHHQQQQQQQQQQQQQPPPPIPANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMRRQQEEMMRRQQEGFKGTFPDAREQEIRMGQMAMGGAMGINNRGAMPPAPVPPGTPAPPGPAAMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRPAPGAEFAPNKRRRY

Target ORF information:

RefSeq Version	NM_001012356.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus non-POU domain containing, octamer-binding (Nono), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012356.1

ORF Insert Sequence:

ATGCAGAGCA ATAAAACCTT TAACTTGGAG AAGCAGAATC ATACTCCAAG GAAGCACCAT 
CAGCATCACC ACCAGCAGCA CCATCAGCAA CAGCAGCAGC AGCAGCAGCA GCAGCAGCAG 
CAGCCACCCC CACCAATACC TGCAAATGGA CAGCAGGCCA GCAGCCAGAA TGAAGGCTTG 
ACTATTGACC TGAAGAATTT TAGGAAACCA GGAGAGAAGA CCTTTACCCA ACGTAGCCGT 
CTCTTTGTGG GCAATCTTCC CCCTGACATC ACTGAGGAGG AAATGAGGAA ACTTTTTGAG 
AAATATGGGA AAGCAGGCGA AGTTTTCATT CATAAGGATA AAGGCTTTGG CTTTATTCGC 
TTGGAAACAC GAACCCTAGC GGAAATTGCC AAAGTGGAGC TGGACAACAT GCCACTCCGT 
GGAAAGCAGC TGCGAGTGCG CTTTGCTTGT CATAGTGCAT CCCTTACGGT TCGCAACCTT 
CCTCAGTACG TGTCCAACGA ACTGCTGGAA GAAGCCTTTT CTGTGTTTGG CCAGGTGGAG 
AGGGCTGTAG TCATTGTGGA TGACCGAGGA AGGCCCTCGG GGAAAGGCAT TGTTGAGTTC 
TCAGGGAAGC CAGCTGCTCG GAAAGCTCTG GACAGATGCA GTGAAGGCTC CTTCTTGCTA 
ACCACATTTC CTCGGCCTGT GACTGTGGAG CCTATGGACC AGTTAGATGA TGAAGAGGGA 
CTTCCGGAGA AGTTGGTTAT AAAAAACCAG CAATTTCACA AGGAGAGAGA ACAGCCACCC 
AGATTTGCAC AGCCTGGGTC CTTTGAGTAT GAGTATGCCA TGCGCTGGAA GGCTCTCATT 
GAGATGGAGA AGCAACAGCA GGATCAAGTG GACCGAAACA TCAAGGAGGC TCGTGAGAAG 
CTGGAGATGG AGATGGAGGC AGCACGCCAT GAGCACCAGG TTATGCTAAT GAGGCAGGAT 
TTGATGAGAC GTCAAGAAGA GCTTCGAAGA ATGGAGGAGC TGCATAACCA AGAGGTTCAG 
AAACGAAAGC AGTTAGAACT CAGGCAGGAA GAGGAACGCA GGCGCCGTGA GGAAGAGATG 
CGGCGACAGC AAGAAGAAAT GATGCGACGG CAGCAGGAAG GATTCAAGGG AACCTTCCCT 
GATGCGAGAG AACAAGAGAT ACGGATGGGC CAAATGGCTA TGGGAGGTGC CATGGGCATA 
AACAATAGAG GCGCCATGCC CCCTGCTCCT GTGCCACCTG GTACTCCAGC TCCTCCAGGA 
CCTGCTGCTA TGATGCCAGA TGGAACCCTT GGATTGACTC CACCAACAAC TGAACGTTTT 
GGCCAAGCTG CTACAATGGA AGGAATTGGA GCAATTGGTG GAACTCCTCC TGCATTCAAC 
CGTCCAGCTC CTGGAGCTGA ATTTGCTCCA AATAAACGCC GCCGATATTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response.
Molecular cell67(3)387-399.e5(2017 Aug)
Morchikh M,Cribier A,Raffel R,Amraoui S,Cau J,Severac D,Dubois E,Schwartz O,Bennasser Y,Benkirane M

Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal differentiation.
Molecular & cellular proteomics : MCP14(1)50-65(2015 Jan)
Sury MD,McShane E,Hernandez-Miranda LR,Birchmeier C,Selbach M

Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.
PLoS genetics9(3)e1003398(2013 Mar)
Wallach T,Schellenberg K,Maier B,Kalathur RK,Porras P,Wanker EE,Futschik ME,Kramer A

Distinct roles of DBHS family members in the circadian transcriptional feedback loop.
Molecular and cellular biology32(22)4585-94(2012 Nov)
Kowalska E,Ripperger JA,Muheim C,Maier B,Kurihara Y,Fox AH,Kramer A,Brown SA

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

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Nono cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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