Eea1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eea1
Entrez Gene ID	314764
Full Name	early endosome antigen 1
General protein information	Preferred Names early endosome antigen 1 Names early endosome antigen 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108086.2	NP_001101556.1	early endosome antigen 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Eea1	NP_001101556.1
Canis lupus familiaris (dog)	EEA1	XP_005629490.1
Gallus gallus (chicken)	EEA1	XP_004937680.1
Xenopus tropicalis (tropical clawed frog)	eea1	XP_002935361.1
Homo sapiens (human)	EEA1	NP_003557.2
	EEA1	XP_001104577.1
Mus musculus (house mouse)	Eea1	NP_001001932.1
Pan troglodytes (chimpanzee)	EEA1	XP_522610.2
Bos taurus (cattle)	EEA1	XP_005206182.1
Danio rerio (zebrafish)	LOC562943	XP_003200485.1

Gene Ontology
Bibliography

Related articles in PubMed

High Resolution Localization of Rab5, EEA1, and Nectin-3 to Tubulobulbar Complexes in the Rat Testis.
Adams A, Wayne Vogl A
Anatomical record (Hoboken, N.J. : 2007)300(6)1160-1170(2017 Jun)

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Bartuzi P, Billadeau DD, Favier R, Rong S, Dekker D, Fedoseienko A, Fieten H, Wijers M, Levels JH, Huijkman N, Kloosterhuis N, van der Molen H, Brufau G, Groen AK, Elliott AM, Kuivenhoven JA, Plecko B, Grangl G, McGaughran J, Horton JD, Burstein E, Hofker MH, van de Sluis B
Nature communications710961(2016 Mar)

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
Urresti J, Ruiz-Meana M, Coccia E, Ar?valo JC, Castellano J, Fern?ndez-Sanz C, Galenkamp KM, Planells-Ferrer L, Moubarak RS, Llecha-Cano N, Reix S, Garc?a-Dorado D, Barneda-Zahonero B, Comella JX
The Journal of biological chemistry291(3)1221-34(2016 Jan)

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Dowdle WE, Nyfeler B, Nagel J, Elling RA, Liu S, Triantafellow E, Menon S, Wang Z, Honda A, Pardee G, Cantwell J, Luu C, Cornella-Taracido I, Harrington E, Fekkes P, Lei H, Fang Q, Digan ME, Burdick D, Powers AF, Helliwell SB, D'Aquin S, Bastien J, Wang H, Wiederschain D, Kuerth J, Bergman P, Schwalb D, Thomas J, Ugwonali S, Harbinski F, Tallarico J, Wilson CJ, Myer VE, Porter JA, Bussiere DE, Finan PM, Labow MA, Mao X, Hamann LG, Manning BD, Valdez RA, Nicholson T, Schirle M, Knapp MS, Keaney EP, Murphy LO
Nature cell biology16(11)1069-79(2014 Nov)

In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA.
Yu T, Calvo L, Anta B, L?pez-Benito S, L?pez-Bellido R, Vicente-Garc?a C, Tessarollo L, Rodriguez RE, Ar?valo JC
The Journal of neuroscience : the official journal of the Society for Neuroscience34(17)6098-106(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PKC-alpha is a necessary regulator of EEA1-dependent Akt signaling in early endosomes.
Title: Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin II-induced, PKC-alpha-dependent Akt activation in endosomes.

The following Eea1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eea1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06653	NM_001108086.2 Latest version!	Rattus norvegicus early endosome antigen 1 (Eea1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eea1 ( NM_001108086.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101556.1 Rattus norvegicus early endosome antigen 1 (Eea1), mRNA.

Price & Availability↑

CloneID	ORa06653
Clone ID Related Accession (Same CDS sequence)	NM_001108086.2
Accession Version	NM_001108086.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4236bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-15
Organism	Rattus norvegicus(Norway rat)
Product	early endosome antigen 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473960.2. On Dec 24, 2015 this sequence version replaced NM_001108086.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTTTCGGA GGATCTTGCA GAGGACTCCT GGGAGAGTTG GCTCTCAAGG TTCTGATTTA 
GATTCATCAG CAACTCCTAT AAATACGGTG GATGTCAATA ATGAAAGTTC TTCAGAGGGT 
TTTATATGTC CCCAGTGTAT GAAATCTCTT GGCTCAGCTG ATGAACTTTT CAAACACTAT 
CAGGCAGTTC ATGATGCCGG TAATGACTCG GGGCATGGTG GAGAGGCCAG TCTTGCTTTG 
ACACGAGATG ACATAGCACT ACTCAGGCAA GAGGTCCAAG ACCTGCAGGC CTCACTTAAG 
GAAGAAAAAT GGTACTCAGA AGAATTAAAG AAAGAATTAG AAAAATATCA AGGGCTACAG 
CAGCAAGAGG CTAAATCTGA TGGATTGGTG ACTGATTCAT CAGCAGAGCT ACAGTCTTTA 
GAGCAACAAT TAGAAGAAGC CCAAACTGAG AATTTTAATA TTAAGCAAAT GAAAGATCTG 
TTTGAACAGA AAGCAGCTCA ACTTGCTACT GAAATTGCAG ATATAAAGTC AAAATATGAT 
GAAGAAAAGG GTCTCCGAGC AGCTGCGGAA CAAAAAGCGA CACATTTGAC AGAAGAATTA 
AGTAAACAGA CGACTGTAAT TCAAGACCTG AAAACTGAGC TGCTTCAGAG ACCTGGTATA 
GAAGATGTCG CTGTACTAAA GAAAGAACTG GTCCAAGTTC AAACTCTAAT GGATAACATG 
ACTTTGGAGC GTGAGAGAGA ATCTGAAAAA CTCAAGGATG AATGTAAAAA GTTACAGTCA 
GAACACGCTA ACTCGGAGGC TACCATAAAC CAGCTAAGGA GTGAACTTGC CAAAGGCCCC 
CAAGAAGTTG CAGTATATGT GCAGGAAATA CAAAAACTTA AAGGTTCAGT TAATGAATTA 
ACACAAAAAA GCCAGACCTT GATGGAGAAA TTGCAGAAGA AAGACCTGGA TTACACCCAC 
TTAGAGGAGA AGCATAACGA AGAGGCACTG AGTAGAAAGA ATACCCAGGC AGCCCTCCAC 
CAAAGGGACC TGGATTGCCA GCAGCTTCAG GCAAGGCTAA CTGCATCCGA AGGCTCGCTA 
CAGAGGATCC AAGGAGAGCT CAGGGAAAAG GGAGAGGCTG CTCAGAAGCT CAAAGAAGAA 
CTGCGGGAAG TAGAGACCAA GCACCAGCAT CTTAAAGTGG AGTTCAAGCA GCTGCAGCAG 
CAGCGGGAAG AGAAGGAGCA GCATGGGCTG CAGCTGCAAG GGGAAGTCAG TCAGTTACAT 
AGCAAACTTC TGGAGACTGA GCGCCAACTA GGGGAAGCTC ACGGTAGGCT GAAGGAGCAG 
AGGCAACTTT CAAGTGAGAA GCTGATGGAT AAGGAACAGC AAGTGGCTGA CTTACAGCTC 
AAGCTCTCTC GTCTGGAAGA GCAGTTGAAG GAAAAGGTAA CAAATTCCAC TGAATTGCAA 
CATCAATTAG AAAAATCAAA GCAACAGCAC CAAGAACAGC AAGCCCTTCA GCAAAGCACT 
ACAGCCAAAC TCCGAGAAGC TCAGAATGAT TTAGAACAAG TGTTACGTCA GATTGGAGAT 
AAGGACCAAA AGATCCAGAA CCTTGAAGCC TTACTACAGA AGAGTAAAGA AAATATTTCC 
TTACTAGAAA AGGAAAGAGA AGACCTTTAT GCAAAAATCC AAGCCGGTGA AGGAGAGACT 
GCTGTCCTTA ACCAGTTGCA AGAGAAAAAC CATGCACTAC AGCAGCAACT AACTCAACTG 
ATGGAGAAGC TGAAGAATCA GTCGGAAAGC CATAAACAAG CTGAGGAGAA CTTGCATGAC 
CAGGTACAGG AGCAGAAGGC ACATCTTCGA GCTGCACAAG ACCGTGTTCT TTCTCTAGAA 
ACCAGTGTCA GTGAACTAAG CAGTCAGTTA AATGAAAGCA AGGAGAAGGT TTCCCAGCTT 
GACATACAGA TTAAAGCCAA AACTGAATTA TTGCTATCAG CAGAAGCAGC AAAAACTGCT 
CAAAGAGCTG ATCTTCAAAA TCATTTGGAC ACAGCTCAAA ATGCACTACA AGATAAACAA 
CAGGAGTTAA ATAAGGTCAG TGCACAGCTG GATCAGGTCA CTGCAAAGTT TCAGGAGAAG 
CAGGAGCATT GCACTCAGCT GGAAAGCCAT CTCAAGGATT ACAAGGAGAA GCACCTCTCT 
CTAGAACAAA AAGCGGAAGA CTTAGAAGGC CAGATTAAGA AACTAGAAGC CAATAATCTT 
GAAGTTAAAG CAAGCAGGGA GCAAGCTGTG CAGAGCCTAC AGCAGCAGAG GCAGCTGAGC 
ACAGACCTAG AGCTCAGGAA TGCAGAGCTC AGGAAGCAGC TTCAAGAGCA GAAGGAAGTA 
GTATCTCATA CAAAATTGGA TCTACAGAAT AAATCTGAAG CCCTTGAAAA TATTAAACAA 
ACCCTCACTA AGAAAGAAGA AGAAAAAGTT GTCTTGAAAC AGGAATTTGA AAAGTTAAGT 
CAAGATTCAG AGGCGCAGCA CAAGGAGCTG AGTGACAGGA TGCAAGCTGC GATCACAGAG 
CTGATGGTGA TGACAGCACA GAAGGACGCT CTCCTGGCTG AGCTCTCCAC AACAAAAGGG 
AAACTGTCAA AAGTTTCAGA TTCTTTACAA ACCTCCAGGA GCGAATTTGA GAAAGAGAGT 
CAGAAAGGAA AGGCTGCTGT ACTAGACTTG GAAAAAGCTT GTAAAGAATT AAAGCATCAG 
CTTCAACAAC AAACAGAAAG TGCACTGAAG GAGCAGAGTG AACTGAAAAA GTCACTGGAG 
AAGGAGAGAG AGACTTCTCA ACAGTTGATG ATAGAACTCA ATTCAGTCAA GGGAGAAGTC 
ACACAGGCTC AAAATACATT AAAGCAGAAG GAGAAAGAAG AGCAGCAGCT TCAGGGGAAC 
ATAAATCAGC TGAAGCAAGC AACTGAGCAA AAGAAAAAGC AAATGGAAGC TCTTCAAGGA 
GAGCTTAAAA ACGTTACTTC ACAAAAGGCC CAGCTGGAGA GTAAACTGCA GCAGCAGGCG 
GCACAGGCAG CCCAGGAACT TGCTGTGGAG AAAGGAAAGC TGTCAGCACT GCAGAGCACC 
TATGACAAGT GCCAGGCCGA CCTGCAACAG CTGCAGTCTG ACCTCTATGG CAAAGAGTCT 
GAACTTCTAG CCACAAGGCA AGACCTTAAG TGTGTAGAAG AGAAGCTTGC TCTGGCACAA 
GAAGACCTGA TTTCAAACAG AAATCAAATT GGAAACCAAA ATAAATCAAT TCAAGAACTG 
CAGGCTGCCA AAGCTGCTTT GGAGCAGGAC TTAGCAAAGA AGGAGGAGGT GCTCAAGGAG 
CAGAGTAAAG CACTGCAGGA TGCGCAGAGA GAAAAGTCAG TGAAGGAAAA AGAACTAGTA 
ACTGAAAAGT CTAAATTGGC AGAGATGGAG GAAATTAAAT GTAGACAAGA AAAAGAAATC 
GCTAAACTCA AAGAAGAACT CAAGTCCCAC AAACAAGAAA GCATAAAGGA AGTAACAAAT 
CTCAAGGATG CCAAACAACT TTTGATTCAA CAGAAATTAG AACTCCAAGG CAAAGTGGAC 
TCACTGAAGG CAGCTCTTGA GCAGGAGAAG GAGCGTCAGC AGCTAATGCG GGAGCAGATG 
AGGAAGGAAG AAGAGAAGCG GAAGGAAGAA TTTTCTGAGA AGGAAGCAAA ACTGCATTCT 
GAAATAAAAG AAAAGGAAGC AGGAGTGAAG AAACATGAAG AAAATGAGGC TAAGCTTACC 
ATGCAGGTCA CAACATTAAA TGAAAACTTG GGCACTGTGA AGAAGGAGTG GCAGTCTAGT 
CAACGGAGAG TTAGTGAGCT TGAGAAGCAG ACGGATGACT TACGGGGTGA AATCGCTGTC 
TTAGAAGCAA CTGTTCAGAA TAATCAGGAT GAAAGAAGAG CACTGCTAGA GAGATGTCTT 
AAAGGAGAAG GTGAAATAGA AAAGCTTCAG ACCAAAGTCC TAGAGTTGCA AAGAAAGCTG 
GATAACACAA CTGCAGCTGT GCAGGAGCTG GGCAGAGAAA ACCAGTCCCT ACAGATCAAA 
CACACACAAG CCCTGAACAG AAAGTGGGCA GAAGACAACG AGGTACAGAA CTGCATGTCC 
TGTGGGAAGT GCTTCTCAGT CACCGTGCGG CGGCACCACT GCCGACAGTG TGGAAATATC 
TTCTGTGCTG AGTGTTCAGC CAAAAACGCC TTAACTCCTT CTTCGAAGAA GCCTGTTCGT 
GTCTGTGATG CATGTTTCAA TGATTTGCAA GGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101556.1
CDS	1..4236
Translation	MFRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICPQCMKSLGSADELFKHYQAVHDAGNDSGHGGEASLALTRDDIALLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKSDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEEKGLRAAAEQKATHLTEELSKQTTVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSEHANSEATINQLRSELAKGPQEVAVYVQEIQKLKGSVNELTQKSQTLMEKLQKKDLDYTHLEEKHNEEALSRKNTQAALHQRDLDCQQLQARLTASEGSLQRIQGELREKGEAAQKLKEELREVETKHQHLKVEFKQLQQQREEKEQHGLQLQGEVSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQQQLTQLMEKLKNQSESHKQAEENLHDQVQEQKAHLRAAQDRVLSLETSVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKVSAQLDQVTAKFQEKQEHCTQLESHLKDYKEKHLSLEQKAEDLEGQIKKLEANNLEVKASREQAVQSLQQQRQLSTDLELRNAELRKQLQEQKEVVSHTKLDLQNKSEALENIKQTLTKKEEEKVVLKQEFEKLSQDSEAQHKELSDRMQAAITELMVMTAQKDALLAELSTTKGKLSKVSDSLQTSRSEFEKESQKGKAAVLDLEKACKELKHQLQQQTESALKEQSELKKSLEKERETSQQLMIELNSVKGEVTQAQNTLKQKEKEEQQLQGNINQLKQATEQKKKQMEALQGELKNVTSQKAQLESKLQQQAAQAAQELAVEKGKLSALQSTYDKCQADLQQLQSDLYGKESELLATRQDLKCVEEKLALAQEDLISNRNQIGNQNKSIQELQAAKAALEQDLAKKEEVLKEQSKALQDAQREKSVKEKELVTEKSKLAEMEEIKCRQEKEIAKLKEELKSHKQESIKEVTNLKDAKQLLIQQKLELQGKVDSLKAALEQEKERQQLMREQMRKEEEKRKEEFSEKEAKLHSEIKEKEAGVKKHEENEAKLTMQVTTLNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMSCGKCFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFNDLQG

Target ORF information:

RefSeq Version	NM_001108086.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus early endosome antigen 1 (Eea1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108086.2

ORF Insert Sequence:

ATGTTTCGGA GGATCTTGCA GAGGACTCCT GGGAGAGTTG GCTCTCAAGG TTCTGATTTA 
GATTCATCAG CAACTCCTAT AAATACGGTG GATGTCAATA ATGAAAGTTC TTCAGAGGGT 
TTTATATGTC CCCAGTGTAT GAAATCTCTT GGCTCAGCTG ATGAACTTTT CAAACACTAT 
CAGGCAGTTC ATGATGCCGG TAATGACTCG GGGCATGGTG GAGAGGCCAG TCTTGCTTTG 
ACACGAGATG ACATAGCACT ACTCAGGCAA GAGGTCCAAG ACCTGCAGGC CTCACTTAAG 
GAAGAAAAAT GGTACTCAGA AGAATTAAAG AAAGAATTAG AAAAATATCA AGGGCTACAG 
CAGCAAGAGG CTAAATCTGA TGGATTGGTG ACTGATTCAT CAGCAGAGCT ACAGTCTTTA 
GAGCAACAAT TAGAAGAAGC CCAAACTGAG AATTTTAATA TTAAGCAAAT GAAAGATCTG 
TTTGAACAGA AAGCAGCTCA ACTTGCTACT GAAATTGCAG ATATAAAGTC AAAATATGAT 
GAAGAAAAGG GTCTCCGAGC AGCTGCGGAA CAAAAAGCGA CACATTTGAC AGAAGAATTA 
AGTAAACAGA CGACTGTAAT TCAAGACCTG AAAACTGAGC TGCTTCAGAG ACCTGGTATA 
GAAGATGTCG CTGTACTAAA GAAAGAACTG GTCCAAGTTC AAACTCTAAT GGATAACATG 
ACTTTGGAGC GTGAGAGAGA ATCTGAAAAA CTCAAGGATG AATGTAAAAA GTTACAGTCA 
GAACACGCTA ACTCGGAGGC TACCATAAAC CAGCTAAGGA GTGAACTTGC CAAAGGCCCC 
CAAGAAGTTG CAGTATATGT GCAGGAAATA CAAAAACTTA AAGGTTCAGT TAATGAATTA 
ACACAAAAAA GCCAGACCTT GATGGAGAAA TTGCAGAAGA AAGACCTGGA TTACACCCAC 
TTAGAGGAGA AGCATAACGA AGAGGCACTG AGTAGAAAGA ATACCCAGGC AGCCCTCCAC 
CAAAGGGACC TGGATTGCCA GCAGCTTCAG GCAAGGCTAA CTGCATCCGA AGGCTCGCTA 
CAGAGGATCC AAGGAGAGCT CAGGGAAAAG GGAGAGGCTG CTCAGAAGCT CAAAGAAGAA 
CTGCGGGAAG TAGAGACCAA GCACCAGCAT CTTAAAGTGG AGTTCAAGCA GCTGCAGCAG 
CAGCGGGAAG AGAAGGAGCA GCATGGGCTG CAGCTGCAAG GGGAAGTCAG TCAGTTACAT 
AGCAAACTTC TGGAGACTGA GCGCCAACTA GGGGAAGCTC ACGGTAGGCT GAAGGAGCAG 
AGGCAACTTT CAAGTGAGAA GCTGATGGAT AAGGAACAGC AAGTGGCTGA CTTACAGCTC 
AAGCTCTCTC GTCTGGAAGA GCAGTTGAAG GAAAAGGTAA CAAATTCCAC TGAATTGCAA 
CATCAATTAG AAAAATCAAA GCAACAGCAC CAAGAACAGC AAGCCCTTCA GCAAAGCACT 
ACAGCCAAAC TCCGAGAAGC TCAGAATGAT TTAGAACAAG TGTTACGTCA GATTGGAGAT 
AAGGACCAAA AGATCCAGAA CCTTGAAGCC TTACTACAGA AGAGTAAAGA AAATATTTCC 
TTACTAGAAA AGGAAAGAGA AGACCTTTAT GCAAAAATCC AAGCCGGTGA AGGAGAGACT 
GCTGTCCTTA ACCAGTTGCA AGAGAAAAAC CATGCACTAC AGCAGCAACT AACTCAACTG 
ATGGAGAAGC TGAAGAATCA GTCGGAAAGC CATAAACAAG CTGAGGAGAA CTTGCATGAC 
CAGGTACAGG AGCAGAAGGC ACATCTTCGA GCTGCACAAG ACCGTGTTCT TTCTCTAGAA 
ACCAGTGTCA GTGAACTAAG CAGTCAGTTA AATGAAAGCA AGGAGAAGGT TTCCCAGCTT 
GACATACAGA TTAAAGCCAA AACTGAATTA TTGCTATCAG CAGAAGCAGC AAAAACTGCT 
CAAAGAGCTG ATCTTCAAAA TCATTTGGAC ACAGCTCAAA ATGCACTACA AGATAAACAA 
CAGGAGTTAA ATAAGGTCAG TGCACAGCTG GATCAGGTCA CTGCAAAGTT TCAGGAGAAG 
CAGGAGCATT GCACTCAGCT GGAAAGCCAT CTCAAGGATT ACAAGGAGAA GCACCTCTCT 
CTAGAACAAA AAGCGGAAGA CTTAGAAGGC CAGATTAAGA AACTAGAAGC CAATAATCTT 
GAAGTTAAAG CAAGCAGGGA GCAAGCTGTG CAGAGCCTAC AGCAGCAGAG GCAGCTGAGC 
ACAGACCTAG AGCTCAGGAA TGCAGAGCTC AGGAAGCAGC TTCAAGAGCA GAAGGAAGTA 
GTATCTCATA CAAAATTGGA TCTACAGAAT AAATCTGAAG CCCTTGAAAA TATTAAACAA 
ACCCTCACTA AGAAAGAAGA AGAAAAAGTT GTCTTGAAAC AGGAATTTGA AAAGTTAAGT 
CAAGATTCAG AGGCGCAGCA CAAGGAGCTG AGTGACAGGA TGCAAGCTGC GATCACAGAG 
CTGATGGTGA TGACAGCACA GAAGGACGCT CTCCTGGCTG AGCTCTCCAC AACAAAAGGG 
AAACTGTCAA AAGTTTCAGA TTCTTTACAA ACCTCCAGGA GCGAATTTGA GAAAGAGAGT 
CAGAAAGGAA AGGCTGCTGT ACTAGACTTG GAAAAAGCTT GTAAAGAATT AAAGCATCAG 
CTTCAACAAC AAACAGAAAG TGCACTGAAG GAGCAGAGTG AACTGAAAAA GTCACTGGAG 
AAGGAGAGAG AGACTTCTCA ACAGTTGATG ATAGAACTCA ATTCAGTCAA GGGAGAAGTC 
ACACAGGCTC AAAATACATT AAAGCAGAAG GAGAAAGAAG AGCAGCAGCT TCAGGGGAAC 
ATAAATCAGC TGAAGCAAGC AACTGAGCAA AAGAAAAAGC AAATGGAAGC TCTTCAAGGA 
GAGCTTAAAA ACGTTACTTC ACAAAAGGCC CAGCTGGAGA GTAAACTGCA GCAGCAGGCG 
GCACAGGCAG CCCAGGAACT TGCTGTGGAG AAAGGAAAGC TGTCAGCACT GCAGAGCACC 
TATGACAAGT GCCAGGCCGA CCTGCAACAG CTGCAGTCTG ACCTCTATGG CAAAGAGTCT 
GAACTTCTAG CCACAAGGCA AGACCTTAAG TGTGTAGAAG AGAAGCTTGC TCTGGCACAA 
GAAGACCTGA TTTCAAACAG AAATCAAATT GGAAACCAAA ATAAATCAAT TCAAGAACTG 
CAGGCTGCCA AAGCTGCTTT GGAGCAGGAC TTAGCAAAGA AGGAGGAGGT GCTCAAGGAG 
CAGAGTAAAG CACTGCAGGA TGCGCAGAGA GAAAAGTCAG TGAAGGAAAA AGAACTAGTA 
ACTGAAAAGT CTAAATTGGC AGAGATGGAG GAAATTAAAT GTAGACAAGA AAAAGAAATC 
GCTAAACTCA AAGAAGAACT CAAGTCCCAC AAACAAGAAA GCATAAAGGA AGTAACAAAT 
CTCAAGGATG CCAAACAACT TTTGATTCAA CAGAAATTAG AACTCCAAGG CAAAGTGGAC 
TCACTGAAGG CAGCTCTTGA GCAGGAGAAG GAGCGTCAGC AGCTAATGCG GGAGCAGATG 
AGGAAGGAAG AAGAGAAGCG GAAGGAAGAA TTTTCTGAGA AGGAAGCAAA ACTGCATTCT 
GAAATAAAAG AAAAGGAAGC AGGAGTGAAG AAACATGAAG AAAATGAGGC TAAGCTTACC 
ATGCAGGTCA CAACATTAAA TGAAAACTTG GGCACTGTGA AGAAGGAGTG GCAGTCTAGT 
CAACGGAGAG TTAGTGAGCT TGAGAAGCAG ACGGATGACT TACGGGGTGA AATCGCTGTC 
TTAGAAGCAA CTGTTCAGAA TAATCAGGAT GAAAGAAGAG CACTGCTAGA GAGATGTCTT 
AAAGGAGAAG GTGAAATAGA AAAGCTTCAG ACCAAAGTCC TAGAGTTGCA AAGAAAGCTG 
GATAACACAA CTGCAGCTGT GCAGGAGCTG GGCAGAGAAA ACCAGTCCCT ACAGATCAAA 
CACACACAAG CCCTGAACAG AAAGTGGGCA GAAGACAACG AGGTACAGAA CTGCATGTCC 
TGTGGGAAGT GCTTCTCAGT CACCGTGCGG CGGCACCACT GCCGACAGTG TGGAAATATC 
TTCTGTGCTG AGTGTTCAGC CAAAAACGCC TTAACTCCTT CTTCGAAGAA GCCTGTTCGT 
GTCTGTGATG CATGTTTCAA TGATTTGCAA GGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High Resolution Localization of Rab5, EEA1, and Nectin-3 to Tubulobulbar Complexes in the Rat Testis.
Anatomical record (Hoboken, N.J. : 2007)300(6)1160-1170(2017 Jun)
Adams A,Wayne Vogl A

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Nature communications710961(2016 Mar)
Bartuzi P,Billadeau DD,Favier R,Rong S,Dekker D,Fedoseienko A,Fieten H,Wijers M,Levels JH,Huijkman N,Kloosterhuis N,van der Molen H,Brufau G,Groen AK,Elliott AM,Kuivenhoven JA,Plecko B,Grangl G,McGaughran J,Horton JD,Burstein E,Hofker MH,van de Sluis B

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
The Journal of biological chemistry291(3)1221-34(2016 Jan)
Urresti J,Ruiz-Meana M,Coccia E,Ar?valo JC,Castellano J,Fern?ndez-Sanz C,Galenkamp KM,Planells-Ferrer L,Moubarak RS,Llecha-Cano N,Reix S,Garc?a-Dorado D,Barneda-Zahonero B,Comella JX

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Nature cell biology16(11)1069-79(2014 Nov)
Dowdle WE,Nyfeler B,Nagel J,Elling RA,Liu S,Triantafellow E,Menon S,Wang Z,Honda A,Pardee G,Cantwell J,Luu C,Cornella-Taracido I,Harrington E,Fekkes P,Lei H,Fang Q,Digan ME,Burdick D,Powers AF,Helliwell SB,D'Aquin S,Bastien J,Wang H,Wiederschain D,Kuerth J,Bergman P,Schwalb D,Thomas J,Ugwonali S,Harbinski F,Tallarico J,Wilson CJ,Myer VE,Porter JA,Bussiere DE,Finan PM,Labow MA,Mao X,Hamann LG,Manning BD,Valdez RA,Nicholson T,Schirle M,Knapp MS,Keaney EP,Murphy LO

In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA.
The Journal of neuroscience : the official journal of the Society for Neuroscience34(17)6098-106(2014 Apr)
Yu T,Calvo L,Anta B,L?pez-Benito S,L?pez-Bellido R,Vicente-Garc?a C,Tessarollo L,Rodriguez RE,Ar?valo JC

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