Qpct cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Qpct
Entrez Gene ID	313837
Full Name	glutaminyl-peptide cyclotransferase
Synonyms	Qpctl1,RGD1562284
General protein information	Preferred Names glutaminyl-peptide cyclotransferase Names glutaminyl-peptide cyclotransferase glutaminyl cyclase glutaminyl-peptide cyclotransferase-like 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q11
Summary	human homolog is a glutaminyl-peptide cyclotransferase that is involved in the presence of pyroglutamyl residues in neuroendocrine peptides [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006239632.3	XP_006239694.1	glutaminyl-peptide cyclotransferase isoform X1
NM_001134557.2	NP_001128029.1	glutaminyl-peptide cyclotransferase

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	QPCT	XP_004935485.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009673	XP_318733.3
Pan troglodytes (chimpanzee)	QPCT	XP_001167364.1
	QPCT	XP_001101173.2
Danio rerio (zebrafish)	qpctla	NP_001038418.1
Neurospora crassa	NCU11249	XP_001728373.1
Bos taurus (cattle)	QPCT	NP_803472.1
Magnaporthe oryzae (rice blast fungus)	MGG_03692	XP_003716189.1
Xenopus tropicalis (tropical clawed frog)	qpct	NP_001017245.1
Xenopus tropicalis (tropical clawed frog)	LOC101732244	XP_004914940.1
Homo sapiens (human)	QPCT	NP_036545.1
Canis lupus familiaris (dog)	QPCT	XP_005630405.1
Mus musculus (house mouse)	Qpct	NP_081731.1
Rattus norvegicus (Norway rat)	RGD1562284	NP_001128029.1
Danio rerio (zebrafish)	qpctlb	XP_001921878.1
Drosophila melanogaster (fruit fly)	isoQC	NP_788550.1

Gene Ontology
Bibliography

Related articles in PubMed

Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding.
Huang KF, Liaw SS, Huang WL, Chia CY, Lo YC, Chen YL, Wang AH
The Journal of biological chemistry286(14)12439-49(2011 Apr)

Molecular cloning, sequence analysis and expression of human pituitary glutaminyl cyclase.
Song I, Chuang CZ, Bateman RC Jr
Journal of molecular endocrinology13(1)77-86(1994 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Qpct gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Qpct cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41749	NM_001134557.2 Latest version!	Rattus norvegicus glutaminyl-peptide cyclotransferase (Qpct), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa29051	XM_006239632.3 Latest version!	Rattus norvegicus glutaminyl-peptide cyclotransferase (Qpct), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Qpct ( NM_001134557.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001128029.1 Rattus norvegicus glutaminyl-peptide cyclotransferase (Qpct), mRNA.

Price & Availability↑

CloneID	ORa41749
Clone ID Related Accession (Same CDS sequence)	NM_001134557.2
Accession Version	NM_001134557.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	glutaminyl-peptide cyclotransferase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473947.1. On Oct 16, 2012 this sequence version replaced NM_001134557.1.

ATGGCAGGCG GCGAAGACAG GCGCGTCGTG GGCACCCGCC ACCTGCTGCT GCTGGCGACC 
ATCCTGTCCC TGACAGCCGG GATTCTGAGT CCGGTCTCCG CTGTTGCCTG GACGCAGGAG 
AAGCACATCA TGCAGCGAAT TCAGAGACTT CAGGCTGAGT GGGTCGTGGA AGTCGACACC 
TTCCTCAGTA GGACGCCCTA CGGATATCGG TCCTTCTCAA ATATCATCAG CACCCTTAAT 
CCGGAAGCGA AACGACACCT GGTCCTTGCC TGCCACTATG ACTCCAAATA CTTTCCTCAA 
TGGGACAGCA GAGTGTTTGT GGGAGCCACT GATTCAGCCG TGCCGTGCGC AATGATGTTG 
GAACTCGCTC GTGCCTTAGA CAAGAAACTC CATTCCTTGA AGGATGTCTC CGGTTCCAGG 
CCGGATCTCT CGCTCCGGCT AATTTTCTTT GATGGGGAAG AGGCCTTTCT TCACTGGTCT 
CCTCAAGATT CTCTGTATGG GTCTCGGCAC TTAGCTCAGA AGATGGCATC AAGCCCTCAC 
CCTCCTGGAT CAAGAGGCAC CAACCAACTG GATGGCATGG ATCTGTTGGT CTTACTGGAT 
TTAATTGGAG CAGCAAATCC AACATTTCCT AATTTTTTCC CCAAGACTAC CAGATGGTTT 
ACTAGACTTC AAGCAATTGA ACAGCAGCTC TCTGAGTTGG GTTTACTCAA GGATCATTCT 
TTGGAGAGGA AATATTTTCA GAATTTTGGT TATGGAAATA TTATCCAGGA TGACCACATT 
CCATTTTTAA GAAAAGGTGT CCCAGTTCTT CACCTGATAG CTTCTCCTTT CCCTGAAGTC 
TGGCACACCA TGGATGACAA TGAAGAAAAT CTGCACTCGT CAACCATTGA CAATCTCAAC 
AAAATCATTC AGGTCTTTGT GTTGGAATAT CTTCACTTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128029.1
CDS	1..942
Translation	MAGGEDRRVVGTRHLLLLATILSLTAGILSPVSAVAWTQEKHIMQRIQRLQAEWVVEVDTFLSRTPYGYRSFSNIISTLNPEAKRHLVLACHYDSKYFPQWDSRVFVGATDSAVPCAMMLELARALDKKLHSLKDVSGSRPDLSLRLIFFDGEEAFLHWSPQDSLYGSRHLAQKMASSPHPPGSRGTNQLDGMDLLVLLDLIGAANPTFPNFFPKTTRWFTRLQAIEQQLSELGLLKDHSLERKYFQNFGYGNIIQDDHIPFLRKGVPVLHLIASPFPEVWHTMDDNEENLHSSTIDNLNKIIQVFVLEYLHL

Target ORF information:

RefSeq Version	NM_001134557.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutaminyl-peptide cyclotransferase (Qpct), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134557.2

ORF Insert Sequence:

ATGGCAGGCG GCGAAGACAG GCGCGTCGTG GGCACCCGCC ACCTGCTGCT GCTGGCGACC 
ATCCTGTCCC TGACAGCCGG GATTCTGAGT CCGGTCTCCG CTGTTGCCTG GACGCAGGAG 
AAGCACATCA TGCAGCGAAT TCAGAGACTT CAGGCTGAGT GGGTCGTGGA AGTCGACACC 
TTCCTCAGTA GGACGCCCTA CGGATATCGG TCCTTCTCAA ATATCATCAG CACCCTTAAT 
CCGGAAGCGA AACGACACCT GGTCCTTGCC TGCCACTATG ACTCCAAATA CTTTCCTCAA 
TGGGACAGCA GAGTGTTTGT GGGAGCCACT GATTCAGCCG TGCCGTGCGC AATGATGTTG 
GAACTCGCTC GTGCCTTAGA CAAGAAACTC CATTCCTTGA AGGATGTCTC CGGTTCCAGG 
CCGGATCTCT CGCTCCGGCT AATTTTCTTT GATGGGGAAG AGGCCTTTCT TCACTGGTCT 
CCTCAAGATT CTCTGTATGG GTCTCGGCAC TTAGCTCAGA AGATGGCATC AAGCCCTCAC 
CCTCCTGGAT CAAGAGGCAC CAACCAACTG GATGGCATGG ATCTGTTGGT CTTACTGGAT 
TTAATTGGAG CAGCAAATCC AACATTTCCT AATTTTTTCC CCAAGACTAC CAGATGGTTT 
ACTAGACTTC AAGCAATTGA ACAGCAGCTC TCTGAGTTGG GTTTACTCAA GGATCATTCT 
TTGGAGAGGA AATATTTTCA GAATTTTGGT TATGGAAATA TTATCCAGGA TGACCACATT 
CCATTTTTAA GAAAAGGTGT CCCAGTTCTT CACCTGATAG CTTCTCCTTT CCCTGAAGTC 
TGGCACACCA TGGATGACAA TGAAGAAAAT CTGCACTCGT CAACCATTGA CAATCTCAAC 
AAAATCATTC AGGTCTTTGT GTTGGAATAT CTTCACTTGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Qpct ( XM_006239632.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239694.1 Rattus norvegicus glutaminyl-peptide cyclotransferase (Qpct), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa29051
Clone ID Related Accession (Same CDS sequence)	XM_006239632.3
Accession Version	XM_006239632.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	glutaminyl-peptide cyclotransferase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239632.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGCG GCGAAGACAG GCGCGTCGTG GGCACCCGCC ACCTGCTGCT GCTGGCGACC 
ATCCTGTCCC TGACAGCCGG GATTCTGAGT CCGGTCTCCG CTGTTGCCTG GACGCAGGAG 
AAGAACTACC ACCAACCAGC ACATCTGAAT TCTTCATCTC TTCGACAAGT GGCAGAAGCC 
ACCAGCATTT CTGAGATGTG GCAAAATGAC TTGAGACCAC TGCTGATAGA ACGATATCCT 
GGATCGCCCG GAAGCTATTC TGCTCGTCAG CACATCATGC AGCGAATTCA GAGACTTCAG 
GCTGAGTGGG TCGTGGAAGT CGACACCTTC CTCAGTAGGA CGCCCTACGG ATATCGGTCC 
TTCTCAAATA TCATCAGCAC CCTTAATCCG GAAGCGAAAC GACACCTGGT CCTTGCCTGC 
CACTATGACT CCAAATACTT TCCTCAATGG GACAGCAGAG TGTTTGTGGG AGCCACTGAT 
TCAGCCGTGC CGTGCGCAAT GATGTTGGAA CTCGCTCGTG CCTTAGACAA GAAACTCCAT 
TCCTTGAAGG ATGTCTCCGG TTCCAGGCCG GATCTCTCGC TCCGGCTAAT TTTCTTTGAT 
GGGGAAGAGG CCTTTCTTCA CTGGTCTCCT CAAGATTCTC TGTATGGGTC TCGGCACTTA 
GCTCAGAAGA TGGCATCAAG CCCTCACCCT CCTGGATCAA GAGGCACCAA CCAACTGGAT 
GGCATGGATC TGTTGGTCTT ACTGGATTTA ATTGGAGCAG CAAATCCAAC ATTTCCTAAT 
TTTTTCCCCA AGACTACCAG ATGGTTTACT AGACTTCAAG CAATTGAACA GCAGCTCTCT 
GAGTTGGGTT TACTCAAGGA TCATTCTTTG GAGAGGAAAT ATTTTCAGAA TTTTGGTTAT 
GGAAATATTA TCCAGGATGA CCACATTCCA TTTTTAAGAA AAGGTGTCCC AGTTCTTCAC 
CTGATAGCTT CTCCTTTCCC TGAAGTCTGG CACACCATGG ATGACAATGA AGAAAATCTG 
CACTCGTCAA CCATTGACAA TCTCAACAAA ATCATTCAGG TCTTTGTGTT GGAATATCTT 
CACTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239694.1
CDS	223..1311
Translation	MAGGEDRRVVGTRHLLLLATILSLTAGILSPVSAVAWTQEKNYHQPAHLNSSSLRQVAEATSISEMWQNDLRPLLIERYPGSPGSYSARQHIMQRIQRLQAEWVVEVDTFLSRTPYGYRSFSNIISTLNPEAKRHLVLACHYDSKYFPQWDSRVFVGATDSAVPCAMMLELARALDKKLHSLKDVSGSRPDLSLRLIFFDGEEAFLHWSPQDSLYGSRHLAQKMASSPHPPGSRGTNQLDGMDLLVLLDLIGAANPTFPNFFPKTTRWFTRLQAIEQQLSELGLLKDHSLERKYFQNFGYGNIIQDDHIPFLRKGVPVLHLIASPFPEVWHTMDDNEENLHSSTIDNLNKIIQVFVLEYLHL

Target ORF information:

RefSeq Version	XM_006239632.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus glutaminyl-peptide cyclotransferase (Qpct), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239632.3

ORF Insert Sequence:

ATGGCAGGCG GCGAAGACAG GCGCGTCGTG GGCACCCGCC ACCTGCTGCT GCTGGCGACC 
ATCCTGTCCC TGACAGCCGG GATTCTGAGT CCGGTCTCCG CTGTTGCCTG GACGCAGGAG 
AAGAACTACC ACCAACCAGC ACATCTGAAT TCTTCATCTC TTCGACAAGT GGCAGAAGCC 
ACCAGCATTT CTGAGATGTG GCAAAATGAC TTGAGACCAC TGCTGATAGA ACGATATCCT 
GGATCGCCCG GAAGCTATTC TGCTCGTCAG CACATCATGC AGCGAATTCA GAGACTTCAG 
GCTGAGTGGG TCGTGGAAGT CGACACCTTC CTCAGTAGGA CGCCCTACGG ATATCGGTCC 
TTCTCAAATA TCATCAGCAC CCTTAATCCG GAAGCGAAAC GACACCTGGT CCTTGCCTGC 
CACTATGACT CCAAATACTT TCCTCAATGG GACAGCAGAG TGTTTGTGGG AGCCACTGAT 
TCAGCCGTGC CGTGCGCAAT GATGTTGGAA CTCGCTCGTG CCTTAGACAA GAAACTCCAT 
TCCTTGAAGG ATGTCTCCGG TTCCAGGCCG GATCTCTCGC TCCGGCTAAT TTTCTTTGAT 
GGGGAAGAGG CCTTTCTTCA CTGGTCTCCT CAAGATTCTC TGTATGGGTC TCGGCACTTA 
GCTCAGAAGA TGGCATCAAG CCCTCACCCT CCTGGATCAA GAGGCACCAA CCAACTGGAT 
GGCATGGATC TGTTGGTCTT ACTGGATTTA ATTGGAGCAG CAAATCCAAC ATTTCCTAAT 
TTTTTCCCCA AGACTACCAG ATGGTTTACT AGACTTCAAG CAATTGAACA GCAGCTCTCT 
GAGTTGGGTT TACTCAAGGA TCATTCTTTG GAGAGGAAAT ATTTTCAGAA TTTTGGTTAT 
GGAAATATTA TCCAGGATGA CCACATTCCA TTTTTAAGAA AAGGTGTCCC AGTTCTTCAC 
CTGATAGCTT CTCCTTTCCC TGAAGTCTGG CACACCATGG ATGACAATGA AGAAAATCTG 
CACTCGTCAA CCATTGACAA TCTCAACAAA ATCATTCAGG TCTTTGTGTT GGAATATCTT 
CACTTGTAA