Plekhm2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Plekhm2
Entrez Gene ID	313667
Full Name	pleckstrin homology and RUN domain containing M2
General protein information	Preferred Names pleckstrin homology and RUN domain containing M2 Names pleckstrin homology domain-containing family M member 2 pleckstrin homology domain containing, family M (with RUN domain) member 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191767.1	NP_001178696.1	pleckstrin homology domain-containing family M member 2

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PLEKHM2	XP_417616.3
Pan troglodytes (chimpanzee)	PLEKHM2	XP_513054.3
Homo sapiens (human)	PLEKHM2	NP_055979.2
Bos taurus (cattle)	PLEKHM2	NP_001179345.1
Mus musculus (house mouse)	Plekhm2	NP_001028322.1
Rattus norvegicus (Norway rat)	Plekhm2	NP_001178696.1
	PLEKHM2	XP_001089676.1
Canis lupus familiaris (dog)	PLEKHM2	XP_005618020.1
Danio rerio (zebrafish)	plekhm2	NP_001124255.1

Gene Ontology
Bibliography

Related articles in PubMed

BORC, a multisubunit complex that regulates lysosome positioning.
Pu J, Schindler C, Jia R, Jarnik M, Backlund P, Bonifacino JS
Developmental cell33(2)176-88(2015 Apr)

Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation.
Ohlson MB, Huang Z, Alto NM, Blanc MP, Dixon JE, Chai J, Miller SI
Cell host & microbe4(5)434-46(2008 Nov)

The Salmonella virulence protein SifA is a G protein antagonist.
Jackson LK, Nawabi P, Hentea C, Roark EA, Haldar K
Proceedings of the National Academy of Sciences of the United States of America105(37)14141-6(2008 Sep)

The intracellular fate of Salmonella depends on the recruitment of kinesin.
Boucrot E, Henry T, Borg JP, Gorvel JP, M?resse S
Science (New York, N.Y.)308(5725)1174-8(2005 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Plekhm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plekhm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07596	NM_001191767.1 Latest version!	Rattus norvegicus pleckstrin homology and RUN domain containing M2 (Plekhm2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Plekhm2 ( NM_001191767.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001178696.1 Rattus norvegicus pleckstrin homology and RUN domain containing M2 (Plekhm2), mRNA.

Price & Availability↑

CloneID	ORa07596
Clone ID Related Accession (Same CDS sequence)	NM_001191767.1
Accession Version	NM_001191767.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3096bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-31
Organism	Rattus norvegicus(Norway rat)
Product	pleckstrin homology domain-containing family M member 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07050301.1. On Jul 17, 2010 this sequence version replaced XM_233611.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCCTC GGGAGGTGAA GGACCGAATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
CTGCAGAGCT ACTTCGCAGC ATGCGAGGAC GAGACCCCTG CCATCCGGAA CCACGACAAG 
GTCCTGCAGC GCCTGTGTGA GCACTTGGAC CACGCCCTGT TGTACGGATT GCAAGACCTG 
TCCTCTGGCT ACTGGGTGGT CGTGGTCCAT TTCACCCGCA GAGAGGCCAT CAGGCAAATT 
GAAGTGCTAC AGCATGTGGC CACCAACCTG GGGCGAAGCC GCGCCTGGCT CTACCTGGCT 
CTCAATGAGA ATTCCTTGGA GAGCTACCTT CGCCTGTTCC AGGAGAACCT GGGTCTGTTA 
CAGAAGTACT ATGTCAGGAA TGCCCTGGTC TGCAGCCACG ATCACTTGAC TCTCTTCCTG 
ACCTTGGTGT CTGGGTTGGA GTTTATTCGG TTCGACCTGG ATCTGGATGC CCCGTACTTA 
GACCTGGCCC CATATATGCC TGACTACTAT AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCAGTCCA CGGCTCAGAC AGCCTGTCCC TGAACTCCTT CAACTCTGTC 
ACCTCCACCA ACCTGGAATG GGATGACAGC GCAATTGCCC CATCTAGTGA GGATTATGAT 
TTTGGAGATG TGTTTCCAGC AGTGCCGTCT GTACCCAGCA CAGACTGGGA AGATGGAGAC 
CTCACAGATA CCATCAGTGG TCCCCGCTCT ACTGCTTCAG ACCTGACCAG TAGCAAGGCA 
TCCACCAAGA GCCCCACCCA GCGCCACAAC CCCTTCAACG AGGAGCAGGC GGAGAGCGCG 
TCATCTGAGA CCACCCCCGT GCACACTACC TCTCAGGAGA AGGAAGAGGC CCAGGCCCCA 
GACCAGCCAG ATGCTTGTAC AGAGCTTGAA GTTATCAGGG TCACCAAGAA GAAGAAGATT 
GGCAAGAAGA AAAAGACCAA GCTGGATGAG GAAGCAAGCC CACTGCACCC CAACTGTAGC 
CAGCAGAAGT GCGGTCGGCA GGGGGACGGT GACGGACTTG TGGGCACCCC AGGCCTGGCG 
CGGAACTGTT CGGACACCAT ACTTGCCTCT CCACAGGAGC AAGGGGAAGG GCCCGGCAGT 
ACCGCCGGGA GCTGTGAGCA CTCAGAGCTC AGCCAGATGG GTTTGCTGAT CCCCGAGATG 
AAGGACACCT CCATGGAGTG CCTAGGACAG CCCCTGAGCA AGGTCATCGA CCAGCTTCAT 
GGCCAGCTGG ACCCTAGCAC CTGGTGCTCC CGTGTCGAGC CCCCGGATCA GTCCTTTCGG 
ACCGGCTCTC CCGGGGAGGC CCCGGAGAAA CCGCCATTTT GCGACTTTAG TGAGGGGCTT 
CCAGCCCCCA TGGACTTCTA CCGGTTTACA GTCGAGAGTC CAAGTACTGT TGCACCAGGT 
GGCGGCCACC ATGACCCTCC AGGGTCTAGC CAACCGCTGC ATGTTCCTGG TAGCCCTGCG 
CCTGCTCTCC AAGAAGAAGA GGGAGGAAGA GGAGAGGGAC AGACATCTCA GCCCCTAGAG 
GACCAGCAAG GGAAGGAGAT TCAGGAGCCA GAGCCTCAGG AACCAGACAG CCAGTTGCCG 
CTGGTCAGCC AGGAGCCTGG GCCTGAACCT GTGTCCCAGC CTGAACCTGG AACCCAGGAA 
ACTCTTTGCA AGCTCAAGGG AGACCAGCCC AGTCCTTGTC TGAGCAGTGC TGAGGACTCC 
GGGGTAGACG AGGGCCAGGG TAGCCCCTCA GAGATGACGC ACCCCTCAGA GTTCAGAGTA 
GACAACAACC ACTTGCTCCT ACTCATGATT CACGTCTTTC GAGAAAATGA AGAACAGTTG 
TTCAAAATGA TCCGGATGAG CACAGGGCAC ATGGAGGGTA ACCTACAGCT GCTCTACGTG 
CTACTCACAG ACTGCTATGT CTACCTGCTT CGGAAAGGGG CCACAGAAAA GCCATACCTG 
GTGGAAGAGG CTGTTTCTTA CAATGAACTT GACTATGTGT CGGTTGGCCT GGACCAACAG 
ACTGTCAAGC TGGTGTGCAC CAACCGCAGG AAGCAGTTTC TGCTGGACAC GGCCGACGTG 
GCCCTGGCTG AGCTGTTCTT GGCGTCTCTG AAGTCAGCCA TGATCAAAGG TTGCCGGGAA 
CCACCCTACC CCAGCGTCTT GACTGATGCC ACCATGGAGA GGCTGGCGCT GGCAAAATTT 
GTCGCCCAGG AATCCAAATG TGAGGCATCC ACTGTGACCG TGCACTTCTA CGGACTTGTA 
CACTGGGAGG ACCCCATGGA AGAGGCCCTG GGCCCTGTTC CTTGCCAGTG CTCACCCGCT 
GAGGGCACGA TCACCAAAGA AGGCATGCTC CACTATAAGG CCAGCACCTC CTACCTGGGC 
AAAGAGCACT GGAAGGCCTG CTTCGTGGTG CTCAGCAATG GGATCCTCTA CCAGTATCCT 
GATCGCACTG ACGTCATCCC CCTGCTCTCC GTGAACATGG GTGGGGAGCA GTGCGGTGGC 
TGCCGGAGAT CCAACACCAC GGATCGGCCC CACGCCTTCC AGGTCATTCT GGCTGACCGG 
CCTTGCCTGG AGCTAAGCGC CGACAGTGAG GCCGAGATGG CAGACTGGAT GCAACATCTT 
TGCCAGGCCG TATCCAAAGG AGTCATACCC CAGGGCATAG CTCCCAGCCC CTGTATCCCT 
TGCTGTCTGG TGATCACGGA GGACCGCCTC TTCACATGCC ACGAAGATTG CCAAACCAGC 
TTCTTCCGCT CCCTGGGCAC AGCCAGACTG GCGGACATCA CTGCTATCTC CACTGAGTTA 
GGCAAGGAGT ACTGTGTCCT GGAGTTCTCC CAGGATAGCC CCCAGCTGCC GAAGCCCTGG 
GTCATCTACA TGAGCTGCAC TTCCGAGTTG GACCGGTTCC TGACCGCCCT GAGCTCTGGG 
TGGAAAGCCA TCTACCAGGT AGACCTTCCT CACAAGGCAA TCCATGAAGC TTCCATCAAG 
CAGAAATTTG AAGATGCCCT GAGCCTCATC CACAGCGCCT GGCAGCGGAG CGACAGCCTC 
TGCCGCGGCA GGGCCTCCCG GGACCCCTGG TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178696.1
CDS	1..3096
Translation	MEPREVKDRILENISLSVKKLQSYFAACEDETPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVVVVHFTRREAIRQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLQKYYVRNALVCSHDHLTLFLTLVSGLEFIRFDLDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTISGPRSTASDLTSSKASTKSPTQRHNPFNEEQAESASSETTPVHTTSQEKEEAQAPDQPDACTELEVIRVTKKKKIGKKKKTKLDEEASPLHPNCSQQKCGRQGDGDGLVGTPGLARNCSDTILASPQEQGEGPGSTAGSCEHSELSQMGLLIPEMKDTSMECLGQPLSKVIDQLHGQLDPSTWCSRVEPPDQSFRTGSPGEAPEKPPFCDFSEGLPAPMDFYRFTVESPSTVAPGGGHHDPPGSSQPLHVPGSPAPALQEEEGGRGEGQTSQPLEDQQGKEIQEPEPQEPDSQLPLVSQEPGPEPVSQPEPGTQETLCKLKGDQPSPCLSSAEDSGVDEGQGSPSEMTHPSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAELFLASLKSAMIKGCREPPYPSVLTDATMERLALAKFVAQESKCEASTVTVHFYGLVHWEDPMEEALGPVPCQCSPAEGTITKEGMLHYKASTSYLGKEHWKACFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRSNTTDRPHAFQVILADRPCLELSADSEAEMADWMQHLCQAVSKGVIPQGIAPSPCIPCCLVITEDRLFTCHEDCQTSFFRSLGTARLADITAISTELGKEYCVLEFSQDSPQLPKPWVIYMSCTSELDRFLTALSSGWKAIYQVDLPHKAIHEASIKQKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	NM_001191767.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus pleckstrin homology and RUN domain containing M2 (Plekhm2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191767.1

ORF Insert Sequence:

ATGGAGCCTC GGGAGGTGAA GGACCGAATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
CTGCAGAGCT ACTTCGCAGC ATGCGAGGAC GAGACCCCTG CCATCCGGAA CCACGACAAG 
GTCCTGCAGC GCCTGTGTGA GCACTTGGAC CACGCCCTGT TGTACGGATT GCAAGACCTG 
TCCTCTGGCT ACTGGGTGGT CGTGGTCCAT TTCACCCGCA GAGAGGCCAT CAGGCAAATT 
GAAGTGCTAC AGCATGTGGC CACCAACCTG GGGCGAAGCC GCGCCTGGCT CTACCTGGCT 
CTCAATGAGA ATTCCTTGGA GAGCTACCTT CGCCTGTTCC AGGAGAACCT GGGTCTGTTA 
CAGAAGTACT ATGTCAGGAA TGCCCTGGTC TGCAGCCACG ATCACTTGAC TCTCTTCCTG 
ACCTTGGTGT CTGGGTTGGA GTTTATTCGG TTCGACCTGG ATCTGGATGC CCCGTACTTA 
GACCTGGCCC CATATATGCC TGACTACTAT AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCAGTCCA CGGCTCAGAC AGCCTGTCCC TGAACTCCTT CAACTCTGTC 
ACCTCCACCA ACCTGGAATG GGATGACAGC GCAATTGCCC CATCTAGTGA GGATTATGAT 
TTTGGAGATG TGTTTCCAGC AGTGCCGTCT GTACCCAGCA CAGACTGGGA AGATGGAGAC 
CTCACAGATA CCATCAGTGG TCCCCGCTCT ACTGCTTCAG ACCTGACCAG TAGCAAGGCA 
TCCACCAAGA GCCCCACCCA GCGCCACAAC CCCTTCAACG AGGAGCAGGC GGAGAGCGCG 
TCATCTGAGA CCACCCCCGT GCACACTACC TCTCAGGAGA AGGAAGAGGC CCAGGCCCCA 
GACCAGCCAG ATGCTTGTAC AGAGCTTGAA GTTATCAGGG TCACCAAGAA GAAGAAGATT 
GGCAAGAAGA AAAAGACCAA GCTGGATGAG GAAGCAAGCC CACTGCACCC CAACTGTAGC 
CAGCAGAAGT GCGGTCGGCA GGGGGACGGT GACGGACTTG TGGGCACCCC AGGCCTGGCG 
CGGAACTGTT CGGACACCAT ACTTGCCTCT CCACAGGAGC AAGGGGAAGG GCCCGGCAGT 
ACCGCCGGGA GCTGTGAGCA CTCAGAGCTC AGCCAGATGG GTTTGCTGAT CCCCGAGATG 
AAGGACACCT CCATGGAGTG CCTAGGACAG CCCCTGAGCA AGGTCATCGA CCAGCTTCAT 
GGCCAGCTGG ACCCTAGCAC CTGGTGCTCC CGTGTCGAGC CCCCGGATCA GTCCTTTCGG 
ACCGGCTCTC CCGGGGAGGC CCCGGAGAAA CCGCCATTTT GCGACTTTAG TGAGGGGCTT 
CCAGCCCCCA TGGACTTCTA CCGGTTTACA GTCGAGAGTC CAAGTACTGT TGCACCAGGT 
GGCGGCCACC ATGACCCTCC AGGGTCTAGC CAACCGCTGC ATGTTCCTGG TAGCCCTGCG 
CCTGCTCTCC AAGAAGAAGA GGGAGGAAGA GGAGAGGGAC AGACATCTCA GCCCCTAGAG 
GACCAGCAAG GGAAGGAGAT TCAGGAGCCA GAGCCTCAGG AACCAGACAG CCAGTTGCCG 
CTGGTCAGCC AGGAGCCTGG GCCTGAACCT GTGTCCCAGC CTGAACCTGG AACCCAGGAA 
ACTCTTTGCA AGCTCAAGGG AGACCAGCCC AGTCCTTGTC TGAGCAGTGC TGAGGACTCC 
GGGGTAGACG AGGGCCAGGG TAGCCCCTCA GAGATGACGC ACCCCTCAGA GTTCAGAGTA 
GACAACAACC ACTTGCTCCT ACTCATGATT CACGTCTTTC GAGAAAATGA AGAACAGTTG 
TTCAAAATGA TCCGGATGAG CACAGGGCAC ATGGAGGGTA ACCTACAGCT GCTCTACGTG 
CTACTCACAG ACTGCTATGT CTACCTGCTT CGGAAAGGGG CCACAGAAAA GCCATACCTG 
GTGGAAGAGG CTGTTTCTTA CAATGAACTT GACTATGTGT CGGTTGGCCT GGACCAACAG 
ACTGTCAAGC TGGTGTGCAC CAACCGCAGG AAGCAGTTTC TGCTGGACAC GGCCGACGTG 
GCCCTGGCTG AGCTGTTCTT GGCGTCTCTG AAGTCAGCCA TGATCAAAGG TTGCCGGGAA 
CCACCCTACC CCAGCGTCTT GACTGATGCC ACCATGGAGA GGCTGGCGCT GGCAAAATTT 
GTCGCCCAGG AATCCAAATG TGAGGCATCC ACTGTGACCG TGCACTTCTA CGGACTTGTA 
CACTGGGAGG ACCCCATGGA AGAGGCCCTG GGCCCTGTTC CTTGCCAGTG CTCACCCGCT 
GAGGGCACGA TCACCAAAGA AGGCATGCTC CACTATAAGG CCAGCACCTC CTACCTGGGC 
AAAGAGCACT GGAAGGCCTG CTTCGTGGTG CTCAGCAATG GGATCCTCTA CCAGTATCCT 
GATCGCACTG ACGTCATCCC CCTGCTCTCC GTGAACATGG GTGGGGAGCA GTGCGGTGGC 
TGCCGGAGAT CCAACACCAC GGATCGGCCC CACGCCTTCC AGGTCATTCT GGCTGACCGG 
CCTTGCCTGG AGCTAAGCGC CGACAGTGAG GCCGAGATGG CAGACTGGAT GCAACATCTT 
TGCCAGGCCG TATCCAAAGG AGTCATACCC CAGGGCATAG CTCCCAGCCC CTGTATCCCT 
TGCTGTCTGG TGATCACGGA GGACCGCCTC TTCACATGCC ACGAAGATTG CCAAACCAGC 
TTCTTCCGCT CCCTGGGCAC AGCCAGACTG GCGGACATCA CTGCTATCTC CACTGAGTTA 
GGCAAGGAGT ACTGTGTCCT GGAGTTCTCC CAGGATAGCC CCCAGCTGCC GAAGCCCTGG 
GTCATCTACA TGAGCTGCAC TTCCGAGTTG GACCGGTTCC TGACCGCCCT GAGCTCTGGG 
TGGAAAGCCA TCTACCAGGT AGACCTTCCT CACAAGGCAA TCCATGAAGC TTCCATCAAG 
CAGAAATTTG AAGATGCCCT GAGCCTCATC CACAGCGCCT GGCAGCGGAG CGACAGCCTC 
TGCCGCGGCA GGGCCTCCCG GGACCCCTGG TGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

BORC, a multisubunit complex that regulates lysosome positioning.
Developmental cell33(2)176-88(2015 Apr)
Pu J,Schindler C,Jia R,Jarnik M,Backlund P,Bonifacino JS

Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation.
Cell host & microbe4(5)434-46(2008 Nov)
Ohlson MB,Huang Z,Alto NM,Blanc MP,Dixon JE,Chai J,Miller SI

The Salmonella virulence protein SifA is a G protein antagonist.
Proceedings of the National Academy of Sciences of the United States of America105(37)14141-6(2008 Sep)
Jackson LK,Nawabi P,Hentea C,Roark EA,Haldar K

The intracellular fate of Salmonella depends on the recruitment of kinesin.
Science (New York, N.Y.)308(5725)1174-8(2005 May)
Boucrot E,Henry T,Borg JP,Gorvel JP,M?resse S

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Plekhm2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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