PLEKHM2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLEKHM2
Entrez Gene ID	23207
Full Name	pleckstrin homology and RUN domain containing M2
Synonyms	SKIP
General protein information	Preferred Names pleckstrin homology and RUN domain containing M2 Names pleckstrin homology domain-containing family M member 2 PH domain-containing family M member 2 SifA (Salmonella-induced filaments A) and kinesin-interacting protein novel RUN and PH domain-containing protein pleckstrin homology domain containing, family M (with RUN domain) member 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.21
Summary	This gene encodes a protein that binds the plus-end directed microtubule motor protein kinesin, together with the lysosomal GTPase Arl8, and is required for lysosomes to distribute away from the microtubule-organizing center. The encoded protein belongs to the multisubunit BLOC-one-related complex that regulates lysosome positioning. It binds a Salmonella effector protein called Salmonella induced filament A and is a critical host determinant in Salmonella pathogenesis. It has a domain architecture consisting of an N-terminal RPIP8, UNC-14, and NESCA (RUN) domain that binds kinesin-1 as well as the lysosomal GTPase Arl8, and a C-terminal pleckstrin homology domain that binds the Salmonella induced filament A effector protein. Naturally occurring mutations in this gene lead to abnormal localization of lysosomes, impaired autophagy flux and are associated with recessive dilated cardiomyopathy and left ventricular noncompaction. [provided by RefSeq, Feb 2017].
Disorder MIM:	609613

mRNA and Protein(s)

mRNA	Protein	Name
XM_005245790.3	XP_005245847.1	pleckstrin homology domain-containing family M member 2 isoform X3
XM_017000758.1	XP_016856247.1	pleckstrin homology domain-containing family M member 2 isoform X2
XM_005245790.4	XP_005245847.1	pleckstrin homology domain-containing family M member 2 isoform X3
XM_005245791.4	XP_005245848.1	pleckstrin homology domain-containing family M member 2 isoform X4
NM_015164.3	NP_055979.2	pleckstrin homology domain-containing family M member 2
NM_015164.2	NP_055979.2	pleckstrin homology domain-containing family M member 2
NM_015164.4	NP_055979.2	pleckstrin homology domain-containing family M member 2
XM_017000757.1	XP_016856246.1	pleckstrin homology domain-containing family M member 2 isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	PLEKHM2	XP_417616.3
Pan troglodytes (chimpanzee)	PLEKHM2	XP_513054.3
Homo sapiens (human)	PLEKHM2	NP_055979.2
Bos taurus (cattle)	PLEKHM2	NP_001179345.1
Mus musculus (house mouse)	Plekhm2	NP_001028322.1
Rattus norvegicus (Norway rat)	Plekhm2	NP_001178696.1
	PLEKHM2	XP_001089676.1
Canis lupus familiaris (dog)	PLEKHM2	XP_005618020.1
Danio rerio (zebrafish)	plekhm2	NP_001124255.1

Gene Ontology
Bibliography

Related articles in PubMed

PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction.
Muhammad E, Levitas A, Singh SR, Braiman A, Ofir R, Etzion S, Sheffield VC, Etzion Y, Carrier L, Parvari R
Human molecular genetics24(25)7227-40(2015 Dec)

BORC, a multisubunit complex that regulates lysosome positioning.
Pu J, Schindler C, Jia R, Jarnik M, Backlund P, Bonifacino JS
Developmental cell33(2)176-88(2015 Apr)

Structural basis for kinesin-1:cargo recognition.
Pernigo S, Lamprecht A, Steiner RA, Dodding MP
Science (New York, N.Y.)340(6130)356-9(2013 Apr)

Salmonella inhibits retrograde trafficking of mannose-6-phosphate receptors and lysosome function.
McGourty K, Thurston TL, Matthews SA, Pinaud L, Mota LJ, Holden DW
Science (New York, N.Y.)338(6109)963-7(2012 Nov)

Arl8 and SKIP act together to link lysosomes to kinesin-1.
Rosa-Ferreira C, Munro S
Developmental cell21(6)1171-8(2011 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The association of PLEKHM2 mutation with dilated cardiomyopathy and left ventricular noncompaction supports the importance of autophagy for normal cardiac function.
Title: PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction.

A dynamic process of kinesin recruitment in Salmonella-infected cells is down-regulated by the SifA-mediated recruitment of SKIP on membranes [SKIP]
Title: The intracellular fate of Salmonella depends on the recruitment of kinesin.

The following PLEKHM2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLEKHM2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13654	NM_015164.4 Latest version!	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$514.50-$720.30 $1029.00
OHu33214	XM_005245790.4 Latest version!	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu33215	XM_005245791.4 Latest version!	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu87070	XM_017000757.1 Latest version!	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu87071	XM_017000758.1 Latest version!	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
View Old Accession Versions >>
OHu33214	XM_005245790.3	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu13654	NM_015164.2	Homo sapiens pleckstrin homology domain containing, family M (with RUN domain) member 2 (PLEKHM2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$514.50-$720.30 $1029.00
OHu13654	NM_015164.3	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$514.50-$720.30 $1029.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLEKHM2 ( NM_015164.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055979.2 Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), mRNA.

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CloneID	OHu13654
Clone ID Related Accession (Same CDS sequence)	NM_015164.3 , NM_015164.2 , NM_015164.4
Accession Version	NM_015164.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3060bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-03
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family M member 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY056873.1, AL121992.24, AB020649.1 and BC040441.1. This sequence is a reference standard in the RefSeqGene project. On Feb 8, 2017 this sequence version replaced NM_015164.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATTATGAT 
TTTGGAGATG TGTTTCCAGC AGTGCCGTCT GTACCCAGCA CAGACTGGGA AGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055979.2
CDS	257..3316
Translation	MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	NM_015164.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015164.3

ORF Insert Sequence:

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATTATGAT 
TTTGGAGATG TGTTTCCAGC AGTGCCGTCT GTACCCAGCA CAGACTGGGA AGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHM2 ( NM_015164.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055979.2 Homo sapiens pleckstrin homology domain containing, family M (with RUN domain) member 2 (PLEKHM2), mRNA.

Price & Availability↑

CloneID	OHu13654
Clone ID Related Accession (Same CDS sequence)	NM_015164.3 , NM_015164.2 , NM_015164.4
Accession Version	NM_015164.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3060bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	pleckstrin homology domain-containing family M member 2
Comment

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATTATGAT 
TTTGGAGATG TGTTTCCAGC AGTGCCGTCT GTACCCAGCA CAGACTGGGA AGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_055979.2

Translation

MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	NM_015164.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens pleckstrin homology domain containing, family M (with RUN domain) member 2 (PLEKHM2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015164.2

ORF Insert Sequence:

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATTATGAT 
TTTGGAGATG TGTTTCCAGC AGTGCCGTCT GTACCCAGCA CAGACTGGGA AGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHM2 ( NM_015164.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055979.2 Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), mRNA.

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CloneID	OHu13654
Clone ID Related Accession (Same CDS sequence)	NM_015164.3 , NM_015164.2 , NM_015164.4
Accession Version	NM_015164.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3060bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family M member 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY056873.1, AL121992.24, AB020649.1 and BC040441.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_015164.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040441.1, SRR1803616.82358.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375799.8/ ENSP00000364956.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATTATGAT 
TTTGGAGATG TGTTTCCAGC AGTGCCGTCT GTACCCAGCA CAGACTGGGA AGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055979.2
CDS	240..3299
Translation	MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	NM_015164.4
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015164.4

ORF Insert Sequence:

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATTATGAT 
TTTGGAGATG TGTTTCCAGC AGTGCCGTCT GTACCCAGCA CAGACTGGGA AGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHM2 ( XM_005245790.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245847.1 Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X3, mRNA.

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CloneID	OHu33214
Clone ID Related Accession (Same CDS sequence)	XM_005245790.3 , XM_005245790.4
Accession Version	XM_005245790.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3000bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family M member 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005245790.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245847.1
CDS	423..3422
Translation	MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	XM_005245790.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245790.3

ORF Insert Sequence:

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHM2 ( XM_005245790.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245847.1 Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X3, mRNA.

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CloneID	OHu33214
Clone ID Related Accession (Same CDS sequence)	XM_005245790.3 , XM_005245790.4
Accession Version	XM_005245790.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3000bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family M member 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005245790.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245847.1
CDS	251..3250
Translation	MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	XM_005245790.4
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245790.4

ORF Insert Sequence:

ATGGAGCCGG GGGAGGTGAA GGACCGGATC CTGGAGAACA TCTCGCTGTC GGTGAAGAAG 
TTGCAGAGCT ATTTTGCTGC ATGTGAGGAT GAGATCCCTG CCATCCGGAA CCATGACAAG 
GTCCTACAGC GTCTGTGTGA GCACCTGGAC CACGCCCTGC TGTACGGACT GCAAGACCTC 
TCCTCTGGCT ACTGGGTGCT CGTGGTGCAT TTTACTCGGA GAGAGGCCAT CAAGCAGATC 
GAGGTGCTGC AGCACGTGGC CACCAACCTG GGGCGCAGCC GTGCCTGGCT GTACCTGGCC 
CTCAACGAGA ACTCCTTGGA GAGCTACCTG CGGTTGTTCC AGGAGAACCT GGGCCTGCTG 
CATAAGTACT ACGTCAAGAA TGCCCTGGTC TGCAGCCACG ATCACCTGAC GCTCTTCCTG 
ACCTTGGTGT CCGGGCTAGA GTTCATTCGT TTCGAGCTGG ATCTGGATGC CCCTTACCTA 
GACCTGGCCC CCTACATGCC CGACTACTAC AAACCTCAGT ACCTGCTGGA CTTTGAAGAC 
CGCCTTCCCA GCTCGGTCCA CGGCTCAGAC AGTCTGTCCC TCAACTCTTT CAACTCCGTC 
ACCTCCACCA ACCTGGAGTG GGATGACAGT GCGATTGCCC CATCTAGTGA GGATGGAGAC 
CTCACAGACA CGGTCAGTGG TCCCCGCTCC ACAGCCTCCG ACCTGACCAG CAGCAAGGCC 
TCCACCAGGA GCCCCACCCA GCGCCAGAAC CCCTTCAACG AGGAGCCGGC AGAGACTGTG 
TCCTCCTCTG ACACCACCCC CGTGCACACC ACCTCTCAGG AGAAGGAGGA GGCCCAGGCC 
CTGGACCCGC CGGATGCCTG CACGGAGCTC GAGGTCATCA GGGTCACCAA GAAGAAGAAA 
ATTGGCAAGA AGAAAAAGAG CAGATCAGAT GAGGAGGCAA GTCCACTCCA CCCCGCCTGC 
AGCCAGAAGA AATGTGCCAA GCAGGGGGAC GGTGACAGCC GCAACGGCAG CCCAAGCCTT 
GGGCGGGACT CGCCAGACAC TATGCTTGCC TCCCCCCAGG AGGAGGGAGA GGGGCCGAGC 
AGCACCACGG AGAGCAGCGA GCGCTCCGAG CCGGGCCTGC TGATCCCTGA GATGAAGGAC 
ACCTCCATGG AGCGCTTGGG GCAGCCCCTG AGCAAGGTTA TCGACCAGCT CAACGGGCAG 
CTGGACCCCA GCACCTGGTG CTCCCGTGCT GAGCCCCCAG ACCAGTCCTT TCGGACCGGC 
TCTCCCGGGG ATGCCCCGGA GAGGCCGCCG CTTTGCGACT TTAGTGAGGG GCTTTCAGCC 
CCAATGGACT TCTACCGCTT TACCGTCGAG AGTCCAAGCA CTGTTACATC AGGTGGCGGC 
CACCATGACC CTGCAGGGCT TGGCCAACCG CTGCATGTTC CTAGTAGCCC TGAGGCTGCT 
GGCCAAGAAG AAGAGGGAGG AGGAGGAGAG GGACAGACGC CTCGGCCCCT AGAGGATACC 
ACGAGGGAGG CTCAGGAGCT GGAGGCCCAG CTGTCCCTGG TCAGGGAGGG GCCTGTGTCT 
GAGCCAGAGC CTGGGACCCA GGAGGTTCTC TGCCAGCTCA AGCGAGACCA GCCCAGCCCG 
TGTCTGAGTA GCGCTGAGGA TTCTGGGGTG GATGAGGGAC AGGGGAGCCC TTCGGAGATG 
GTCCATTCCT CGGAGTTCAG AGTAGACAAC AATCACCTGC TCCTGCTCAT GATCCACGTG 
TTCCGAGAAA ACGAAGAGCA GCTGTTCAAA ATGATCCGGA TGAGCACCGG GCACATGGAG 
GGCAACCTGC AGCTGCTGTA CGTGCTGCTC ACAGACTGCT ATGTCTACCT GCTCCGGAAA 
GGGGCCACAG AGAAGCCATA CCTGGTGGAA GAGGCCGTTT CTTACAATGA ACTTGACTAT 
GTGTCGGTTG GCCTTGACCA GCAGACGGTG AAGCTGGTGT GCACCAACCG CAGGAAGCAG 
TTTCTGCTGG ACACGGCTGA TGTGGCGCTG GCTGAGTTCT TTTTGGCTTC TTTGAAGTCA 
GCCATGATCA AAGGCTGTCG AGAACCTCCC TACCCCAGCA TCCTGACGGA TGCCACCATG 
GAGAAGCTGG CACTGGCCAA ATTTGTGGCC CAAGAATCGA AGTGTGAGGC ATCTGCTGTC 
ACCGTGCGCT TCTACGGCCT TGTGCACTGG GAGGACCCCA CAGACGAGTC CCTGGGCCCC 
ACGCCCTGCC ACTGCTCACC CCCCGAGGGC ACCATCACCA AAGAAGGCAT GCTGCACTAC 
AAGGCGGGCA CCTCCTACCT GGGCAAGGAA CACTGGAAGA CGTGCTTCGT GGTGCTCAGC 
AACGGGATCC TCTACCAGTA CCCGGACCGC ACCGACGTCA TCCCTCTGCT CTCGGTGAAC 
ATGGGGGGGG AGCAGTGCGG TGGCTGCCGG AGAGCCAACA CCACGGATCG GCCCCACGCC 
TTCCAGGTCA TTCTCTCCGA CCGGCCCTGC CTGGAGCTAA GTGCCGAGAG CGAGGCCGAG 
ATGGCCGAGT GGATGCAGCA TCTCTGCCAG GCTGTGTCCA AAGGGGTCAT CCCCCAGGGC 
GTAGCTCCCA GCCCCTGCAT ACCCTGCTGC CTGGTCCTCA CGGATGACCG CCTCTTTACG 
TGCCATGAGG ATTGCCAGAC CAGCTTCTTC CGCTCTTTGG GCACAGCCAA GCTGGGCGAC 
ATCAGCGCCG TCTCCACCGA GCCGGGCAAG GAGTACTGCG TCTTGGAGTT CTCCCAGGAC 
AGCCAGCAGC TCCTCCCGCC CTGGGTCATC TACCTGAGCT GCACTTCTGA ACTGGACCGA 
TTGCTGTCTG CACTGAACTC TGGGTGGAAA ACCATCTATC AGGTGGACCT CCCCCACACG 
GCGATCCAGG AAGCCTCCAA CAAGAAGAAA TTCGAGGATG CCTTGAGCCT CATCCACAGC 
GCCTGGCAGC GGAGCGACAG TCTCTGCCGC GGCCGAGCCT CCCGAGACCC CTGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHM2 ( XM_005245791.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245848.1 Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu33215
Clone ID Related Accession (Same CDS sequence)	XM_005245791.4
Accession Version	XM_005245791.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2451bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family M member 2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005245791.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCGCAC CCTTTGCATC AGGGACCGAG GAAGAAGCTG CAGATTATGA TTTTGGAGAT 
GTGTTTCCAG CAGTGCCGTC TGTACCCAGC ACAGACTGGG AAGATGGAGA CCTCACAGAC 
ACGGTCAGTG GTCCCCGCTC CACAGCCTCC GACCTGACCA GCAGCAAGGC CTCCACCAGG 
AGCCCCACCC AGCGCCAGAA CCCCTTCAAC GAGGAGCCGG CAGAGACTGT GTCCTCCTCT 
GACACCACCC CCGTGCACAC CACCTCTCAG GAGAAGGAGG AGGCCCAGGC CCTGGACCCG 
CCGGATGCCT GCACGGAGCT CGAGGTCATC AGGGTCACCA AGAAGAAGAA AATTGGCAAG 
AAGAAAAAGA GCAGATCAGA TGAGGAGGCA AGTCCACTCC ACCCCGCCTG CAGCCAGAAG 
AAATGTGCCA AGCAGGGGGA CGGTGACAGC CGCAACGGCA GCCCAAGCCT TGGGCGGGAC 
TCGCCAGACA CTATGCTTGC CTCCCCCCAG GAGGAGGGAG AGGGGCCGAG CAGCACCACG 
GAGAGCAGCG AGCGCTCCGA GCCGGGCCTG CTGATCCCTG AGATGAAGGA CACCTCCATG 
GAGCGCTTGG GGCAGCCCCT GAGCAAGGTT ATCGACCAGC TCAACGGGCA GCTGGACCCC 
AGCACCTGGT GCTCCCGTGC TGAGCCCCCA GACCAGTCCT TTCGGACCGG CTCTCCCGGG 
GATGCCCCGG AGAGGCCGCC GCTTTGCGAC TTTAGTGAGG GGCTTTCAGC CCCAATGGAC 
TTCTACCGCT TTACCGTCGA GAGTCCAAGC ACTGTTACAT CAGGTGGCGG CCACCATGAC 
CCTGCAGGGC TTGGCCAACC GCTGCATGTT CCTAGTAGCC CTGAGGCTGC TGGCCAAGAA 
GAAGAGGGAG GAGGAGGAGA GGGACAGACG CCTCGGCCCC TAGAGGATAC CACGAGGGAG 
GCTCAGGAGC TGGAGGCCCA GCTGTCCCTG GTCAGGGAGG GGCCTGTGTC TGAGCCAGAG 
CCTGGGACCC AGGAGGTTCT CTGCCAGCTC AAGCGAGACC AGCCCAGCCC GTGTCTGAGT 
AGCGCTGAGG ATTCTGGGGT GGATGAGGGA CAGGGGAGCC CTTCGGAGAT GGTCCATTCC 
TCGGAGTTCA GAGTAGACAA CAATCACCTG CTCCTGCTCA TGATCCACGT GTTCCGAGAA 
AACGAAGAGC AGCTGTTCAA AATGATCCGG ATGAGCACCG GGCACATGGA GGGCAACCTG 
CAGCTGCTGT ACGTGCTGCT CACAGACTGC TATGTCTACC TGCTCCGGAA AGGGGCCACA 
GAGAAGCCAT ACCTGGTGGA AGAGGCCGTT TCTTACAATG AACTTGACTA TGTGTCGGTT 
GGCCTTGACC AGCAGACGGT GAAGCTGGTG TGCACCAACC GCAGGAAGCA GTTTCTGCTG 
GACACGGCTG ATGTGGCGCT GGCTGAGTTC TTTTTGGCTT CTTTGAAGTC AGCCATGATC 
AAAGGCTGTC GAGAACCTCC CTACCCCAGC ATCCTGACGG ATGCCACCAT GGAGAAGCTG 
GCACTGGCCA AATTTGTGGC CCAAGAATCG AAGTGTGAGG CATCTGCTGT CACCGTGCGC 
TTCTACGGCC TTGTGCACTG GGAGGACCCC ACAGACGAGT CCCTGGGCCC CACGCCCTGC 
CACTGCTCAC CCCCCGAGGG CACCATCACC AAAGAAGGCA TGCTGCACTA CAAGGCGGGC 
ACCTCCTACC TGGGCAAGGA ACACTGGAAG ACGTGCTTCG TGGTGCTCAG CAACGGGATC 
CTCTACCAGT ACCCGGACCG CACCGACGTC ATCCCTCTGC TCTCGGTGAA CATGGGGGGG 
GAGCAGTGCG GTGGCTGCCG GAGAGCCAAC ACCACGGATC GGCCCCACGC CTTCCAGGTC 
ATTCTCTCCG ACCGGCCCTG CCTGGAGCTA AGTGCCGAGA GCGAGGCCGA GATGGCCGAG 
TGGATGCAGC ATCTCTGCCA GGCTGTGTCC AAAGGGGTCA TCCCCCAGGG CGTAGCTCCC 
AGCCCCTGCA TACCCTGCTG CCTGGTCCTC ACGGATGACC GCCTCTTTAC GTGCCATGAG 
GATTGCCAGA CCAGCTTCTT CCGCTCTTTG GGCACAGCCA AGCTGGGCGA CATCAGCGCC 
GTCTCCACCG AGCCGGGCAA GGAGTACTGC GTCTTGGAGT TCTCCCAGGA CAGCCAGCAG 
CTCCTCCCGC CCTGGGTCAT CTACCTGAGC TGCACTTCTG AACTGGACCG ATTGCTGTCT 
GCACTGAACT CTGGGTGGAA AACCATCTAT CAGGTGGACC TCCCCCACAC GGCGATCCAG 
GAAGCCTCCA ACAAGAAGAA ATTCGAGGAT GCCTTGAGCC TCATCCACAG CGCCTGGCAG 
CGGAGCGACA GTCTCTGCCG CGGCCGAGCC TCCCGAGACC CCTGGTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245848.1
CDS	105..2555
Translation	MVAPFASGTEEEAADYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	XM_005245791.4
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245791.4

ORF Insert Sequence:

ATGGTCGCAC CCTTTGCATC AGGGACCGAG GAAGAAGCTG CAGATTATGA TTTTGGAGAT 
GTGTTTCCAG CAGTGCCGTC TGTACCCAGC ACAGACTGGG AAGATGGAGA CCTCACAGAC 
ACGGTCAGTG GTCCCCGCTC CACAGCCTCC GACCTGACCA GCAGCAAGGC CTCCACCAGG 
AGCCCCACCC AGCGCCAGAA CCCCTTCAAC GAGGAGCCGG CAGAGACTGT GTCCTCCTCT 
GACACCACCC CCGTGCACAC CACCTCTCAG GAGAAGGAGG AGGCCCAGGC CCTGGACCCG 
CCGGATGCCT GCACGGAGCT CGAGGTCATC AGGGTCACCA AGAAGAAGAA AATTGGCAAG 
AAGAAAAAGA GCAGATCAGA TGAGGAGGCA AGTCCACTCC ACCCCGCCTG CAGCCAGAAG 
AAATGTGCCA AGCAGGGGGA CGGTGACAGC CGCAACGGCA GCCCAAGCCT TGGGCGGGAC 
TCGCCAGACA CTATGCTTGC CTCCCCCCAG GAGGAGGGAG AGGGGCCGAG CAGCACCACG 
GAGAGCAGCG AGCGCTCCGA GCCGGGCCTG CTGATCCCTG AGATGAAGGA CACCTCCATG 
GAGCGCTTGG GGCAGCCCCT GAGCAAGGTT ATCGACCAGC TCAACGGGCA GCTGGACCCC 
AGCACCTGGT GCTCCCGTGC TGAGCCCCCA GACCAGTCCT TTCGGACCGG CTCTCCCGGG 
GATGCCCCGG AGAGGCCGCC GCTTTGCGAC TTTAGTGAGG GGCTTTCAGC CCCAATGGAC 
TTCTACCGCT TTACCGTCGA GAGTCCAAGC ACTGTTACAT CAGGTGGCGG CCACCATGAC 
CCTGCAGGGC TTGGCCAACC GCTGCATGTT CCTAGTAGCC CTGAGGCTGC TGGCCAAGAA 
GAAGAGGGAG GAGGAGGAGA GGGACAGACG CCTCGGCCCC TAGAGGATAC CACGAGGGAG 
GCTCAGGAGC TGGAGGCCCA GCTGTCCCTG GTCAGGGAGG GGCCTGTGTC TGAGCCAGAG 
CCTGGGACCC AGGAGGTTCT CTGCCAGCTC AAGCGAGACC AGCCCAGCCC GTGTCTGAGT 
AGCGCTGAGG ATTCTGGGGT GGATGAGGGA CAGGGGAGCC CTTCGGAGAT GGTCCATTCC 
TCGGAGTTCA GAGTAGACAA CAATCACCTG CTCCTGCTCA TGATCCACGT GTTCCGAGAA 
AACGAAGAGC AGCTGTTCAA AATGATCCGG ATGAGCACCG GGCACATGGA GGGCAACCTG 
CAGCTGCTGT ACGTGCTGCT CACAGACTGC TATGTCTACC TGCTCCGGAA AGGGGCCACA 
GAGAAGCCAT ACCTGGTGGA AGAGGCCGTT TCTTACAATG AACTTGACTA TGTGTCGGTT 
GGCCTTGACC AGCAGACGGT GAAGCTGGTG TGCACCAACC GCAGGAAGCA GTTTCTGCTG 
GACACGGCTG ATGTGGCGCT GGCTGAGTTC TTTTTGGCTT CTTTGAAGTC AGCCATGATC 
AAAGGCTGTC GAGAACCTCC CTACCCCAGC ATCCTGACGG ATGCCACCAT GGAGAAGCTG 
GCACTGGCCA AATTTGTGGC CCAAGAATCG AAGTGTGAGG CATCTGCTGT CACCGTGCGC 
TTCTACGGCC TTGTGCACTG GGAGGACCCC ACAGACGAGT CCCTGGGCCC CACGCCCTGC 
CACTGCTCAC CCCCCGAGGG CACCATCACC AAAGAAGGCA TGCTGCACTA CAAGGCGGGC 
ACCTCCTACC TGGGCAAGGA ACACTGGAAG ACGTGCTTCG TGGTGCTCAG CAACGGGATC 
CTCTACCAGT ACCCGGACCG CACCGACGTC ATCCCTCTGC TCTCGGTGAA CATGGGGGGG 
GAGCAGTGCG GTGGCTGCCG GAGAGCCAAC ACCACGGATC GGCCCCACGC CTTCCAGGTC 
ATTCTCTCCG ACCGGCCCTG CCTGGAGCTA AGTGCCGAGA GCGAGGCCGA GATGGCCGAG 
TGGATGCAGC ATCTCTGCCA GGCTGTGTCC AAAGGGGTCA TCCCCCAGGG CGTAGCTCCC 
AGCCCCTGCA TACCCTGCTG CCTGGTCCTC ACGGATGACC GCCTCTTTAC GTGCCATGAG 
GATTGCCAGA CCAGCTTCTT CCGCTCTTTG GGCACAGCCA AGCTGGGCGA CATCAGCGCC 
GTCTCCACCG AGCCGGGCAA GGAGTACTGC GTCTTGGAGT TCTCCCAGGA CAGCCAGCAG 
CTCCTCCCGC CCTGGGTCAT CTACCTGAGC TGCACTTCTG AACTGGACCG ATTGCTGTCT 
GCACTGAACT CTGGGTGGAA AACCATCTAT CAGGTGGACC TCCCCCACAC GGCGATCCAG 
GAAGCCTCCA ACAAGAAGAA ATTCGAGGAT GCCTTGAGCC TCATCCACAG CGCCTGGCAG 
CGGAGCGACA GTCTCTGCCG CGGCCGAGCC TCCCGAGACC CCTGGTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHM2 ( XM_017000757.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856246.1 Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu87070
Clone ID Related Accession (Same CDS sequence)	XM_017000757.1
Accession Version	XM_017000757.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3099bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family M member 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCAGA GCTGCATCCA GCAGGTTGGG GCCTGTATGC ACCCTAGCCA GGATGGAGTG 
GGAAGGAAGT GCGCAATTCT GACTCCACAA ACACCTTTGT TGCAGAGCTA TTTTGCTGCA 
TGTGAGGATG AGATCCCTGC CATCCGGAAC CATGACAAGG TCCTACAGCG TCTGTGTGAG 
CACCTGGACC ACGCCCTGCT GTACGGACTG CAAGACCTCT CCTCTGGCTA CTGGGTGCTC 
GTGGTGCATT TTACTCGGAG AGAGGCCATC AAGCAGATCG AGGTGCTGCA GCACGTGGCC 
ACCAACCTGG GGCGCAGCCG TGCCTGGCTG TACCTGGCCC TCAACGAGAA CTCCTTGGAG 
AGCTACCTGC GGTTGTTCCA GGAGAACCTG GGCCTGCTGC ATAAGTACTA CGTCAAGAAT 
GCCCTGGTCT GCAGCCACGA TCACCTGACG CTCTTCCTGA CCTTGGTGTC CGGGCTAGAG 
TTCATTCGTT TCGAGCTGGA TCTGGATGCC CCTTACCTAG ACCTGGCCCC CTACATGCCC 
GACTACTACA AACCTCAGTA CCTGCTGGAC TTTGAAGACC GCCTTCCCAG CTCGGTCCAC 
GGCTCAGACA GTCTGTCCCT CAACTCTTTC AACTCCGTCA CCTCCACCAA CCTGGAGTGG 
GATGACAGTG CGATTGCCCC ATCTAGTGAG GATTATGATT TTGGAGATGT GTTTCCAGCA 
GTGCCGTCTG TACCCAGCAC AGACTGGGAA GATGGAGACC TCACAGACAC GGTCAGTGGT 
CCCCGCTCCA CAGCCTCCGA CCTGACCAGC AGCAAGGCCT CCACCAGGAG CCCCACCCAG 
CGCCAGAACC CCTTCAACGA GGAGCCGGCA GAGACTGTGT CCTCCTCTGA CACCACCCCC 
GTGCACACCA CCTCTCAGGA GAAGGAGGAG GCCCAGGCCC TGGACCCGCC GGATGCCTGC 
ACGGAGCTCG AGGTCATCAG GGTCACCAAG AAGAAGAAAA TTGGCAAGAA GAAAAAGAGC 
AGATCAGATG AGGAGGCAAG TCCACTCCAC CCCGCCTGCA GCCAGAAGAA ATGTGCCAAG 
CAGGGGGACG GTGACAGCCG CAACGGCAGC CCAAGCCTTG GGCGGGACTC GCCAGACACT 
ATGCTTGCCT CCCCCCAGGA GGAGGGAGAG GGGCCGAGCA GCACCACGGA GAGCAGCGAG 
CGCTCCGAGC CGGGCCTGCT GATCCCTGAG ATGAAGGACA CCTCCATGGA GCGCTTGGGG 
CAGCCCCTGA GCAAGGTTAT CGACCAGCTC AACGGGCAGC TGGACCCCAG CACCTGGTGC 
TCCCGTGCTG AGCCCCCAGA CCAGTCCTTT CGGACCGGCT CTCCCGGGGA TGCCCCGGAG 
AGGCCGCCGC TTTGCGACTT TAGTGAGGGG CTTTCAGCCC CAATGGACTT CTACCGCTTT 
ACCGTCGAGA GTCCAAGCAC TGTTACATCA GGTGGCGGCC ACCATGACCC TGCAGGGCTT 
GGCCAACCGC TGCATGTTCC TAGTAGCCCT GAGGCTGCTG GCCAAGAAGA AGAGGGAGGA 
GGAGGAGAGG GACAGACGCC TCGGCCCCTA GAGGATACCA CGAGGGAGGC TCAGGAGCTG 
GAGGCCCAGC TGTCCCTGGT CAGGGAGGGG CCTGTGTCTG AGCCAGAGCC TGGGACCCAG 
GAGGTTCTCT GCCAGCTCAA GCGAGACCAG CCCAGCCCGT GTCTGAGTAG CGCTGAGGAT 
TCTGGGGTGG ATGAGGGACA GGGGAGCCCT TCGGAGATGG TCCATTCCTC GGAGTTCAGA 
GTAGACAACA ATCACCTGCT CCTGCTCATG ATCCACGTGT TCCGAGAAAA CGAAGAGCAG 
CTGTTCAAAA TGATCCGGAT GAGCACCGGG CACATGGAGG GCAACCTGCA GCTGCTGTAC 
GTGCTGCTCA CAGACTGCTA TGTCTACCTG CTCCGGAAAG GGGCCACAGA GAAGCCATAC 
CTGGTGGAAG AGGCCGTTTC TTACAATGAA CTTGACTATG TGTCGGTTGG CCTTGACCAG 
CAGACGGTGA AGCTGGTGTG CACCAACCGC AGGAAGCAGT TTCTGCTGGA CACGGCTGAT 
GTGGCGCTGG CTGAGTTCTT TTTGGCTTCT TTGAAGTCAG CCATGATCAA AGGCTGTCGA 
GAACCTCCCT ACCCCAGCAT CCTGACGGAT GCCACCATGG AGAAGCTGGC ACTGGCCAAA 
TTTGTGGCCC AAGAATCGAA GTGTGAGGCA TCTGCTGTCA CCGTGCGCTT CTACGGCCTT 
GTGCACTGGG AGGACCCCAC AGACGAGTCC CTGGGCCCCA CGCCCTGCCA CTGCTCACCC 
CCCGAGGGCA CCATCACCAA AGAAGGCATG CTGCACTACA AGGCGGGCAC CTCCTACCTG 
GGCAAGGAAC ACTGGAAGAC GTGCTTCGTG GTGCTCAGCA ACGGGATCCT CTACCAGTAC 
CCGGACCGCA CCGACGTCAT CCCTCTGCTC TCGGTGAACA TGGGGGGGGA GCAGTGCGGT 
GGCTGCCGGA GAGCCAACAC CACGGATCGG CCCCACGCCT TCCAGGTCAT TCTCTCCGAC 
CGGCCCTGCC TGGAGCTAAG TGCCGAGAGC GAGGCCGAGA TGGCCGAGTG GATGCAGCAT 
CTCTGCCAGG CTGTGTCCAA AGGGGTCATC CCCCAGGGCG TAGCTCCCAG CCCCTGCATA 
CCCTGCTGCC TGGTCCTCAC GGATGACCGC CTCTTTACGT GCCATGAGGA TTGCCAGACC 
AGCTTCTTCC GCTCTTTGGG CACAGCCAAG CTGGGCGACA TCAGCGCCGT CTCCACCGAG 
CCGGGCAAGG AGTACTGCGT CTTGGAGTTC TCCCAGGACA GCCAGCAGCT CCTCCCGCCC 
TGGGTCATCT ACCTGAGCTG CACTTCTGAA CTGGACCGAT TGCTGTCTGC ACTGAACTCT 
GGGTGGAAAA CCATCTATCA GGTGGACCTC CCCCACACGG CGATCCAGGA AGCCTCCAAC 
AAGAAGAAAT TCGAGGATGC CTTGAGCCTC ATCCACAGCG CCTGGCAGCG GAGCGACAGT 
CTCTGCCGCG GCCGAGCCTC CCGAGACCCC TGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856246.1
CDS	96..3194
Translation	MNQSCIQQVGACMHPSQDGVGRKCAILTPQTPLLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	XM_017000757.1
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000757.1

ORF Insert Sequence:

ATGAACCAGA GCTGCATCCA GCAGGTTGGG GCCTGTATGC ACCCTAGCCA GGATGGAGTG 
GGAAGGAAGT GCGCAATTCT GACTCCACAA ACACCTTTGT TGCAGAGCTA TTTTGCTGCA 
TGTGAGGATG AGATCCCTGC CATCCGGAAC CATGACAAGG TCCTACAGCG TCTGTGTGAG 
CACCTGGACC ACGCCCTGCT GTACGGACTG CAAGACCTCT CCTCTGGCTA CTGGGTGCTC 
GTGGTGCATT TTACTCGGAG AGAGGCCATC AAGCAGATCG AGGTGCTGCA GCACGTGGCC 
ACCAACCTGG GGCGCAGCCG TGCCTGGCTG TACCTGGCCC TCAACGAGAA CTCCTTGGAG 
AGCTACCTGC GGTTGTTCCA GGAGAACCTG GGCCTGCTGC ATAAGTACTA CGTCAAGAAT 
GCCCTGGTCT GCAGCCACGA TCACCTGACG CTCTTCCTGA CCTTGGTGTC CGGGCTAGAG 
TTCATTCGTT TCGAGCTGGA TCTGGATGCC CCTTACCTAG ACCTGGCCCC CTACATGCCC 
GACTACTACA AACCTCAGTA CCTGCTGGAC TTTGAAGACC GCCTTCCCAG CTCGGTCCAC 
GGCTCAGACA GTCTGTCCCT CAACTCTTTC AACTCCGTCA CCTCCACCAA CCTGGAGTGG 
GATGACAGTG CGATTGCCCC ATCTAGTGAG GATTATGATT TTGGAGATGT GTTTCCAGCA 
GTGCCGTCTG TACCCAGCAC AGACTGGGAA GATGGAGACC TCACAGACAC GGTCAGTGGT 
CCCCGCTCCA CAGCCTCCGA CCTGACCAGC AGCAAGGCCT CCACCAGGAG CCCCACCCAG 
CGCCAGAACC CCTTCAACGA GGAGCCGGCA GAGACTGTGT CCTCCTCTGA CACCACCCCC 
GTGCACACCA CCTCTCAGGA GAAGGAGGAG GCCCAGGCCC TGGACCCGCC GGATGCCTGC 
ACGGAGCTCG AGGTCATCAG GGTCACCAAG AAGAAGAAAA TTGGCAAGAA GAAAAAGAGC 
AGATCAGATG AGGAGGCAAG TCCACTCCAC CCCGCCTGCA GCCAGAAGAA ATGTGCCAAG 
CAGGGGGACG GTGACAGCCG CAACGGCAGC CCAAGCCTTG GGCGGGACTC GCCAGACACT 
ATGCTTGCCT CCCCCCAGGA GGAGGGAGAG GGGCCGAGCA GCACCACGGA GAGCAGCGAG 
CGCTCCGAGC CGGGCCTGCT GATCCCTGAG ATGAAGGACA CCTCCATGGA GCGCTTGGGG 
CAGCCCCTGA GCAAGGTTAT CGACCAGCTC AACGGGCAGC TGGACCCCAG CACCTGGTGC 
TCCCGTGCTG AGCCCCCAGA CCAGTCCTTT CGGACCGGCT CTCCCGGGGA TGCCCCGGAG 
AGGCCGCCGC TTTGCGACTT TAGTGAGGGG CTTTCAGCCC CAATGGACTT CTACCGCTTT 
ACCGTCGAGA GTCCAAGCAC TGTTACATCA GGTGGCGGCC ACCATGACCC TGCAGGGCTT 
GGCCAACCGC TGCATGTTCC TAGTAGCCCT GAGGCTGCTG GCCAAGAAGA AGAGGGAGGA 
GGAGGAGAGG GACAGACGCC TCGGCCCCTA GAGGATACCA CGAGGGAGGC TCAGGAGCTG 
GAGGCCCAGC TGTCCCTGGT CAGGGAGGGG CCTGTGTCTG AGCCAGAGCC TGGGACCCAG 
GAGGTTCTCT GCCAGCTCAA GCGAGACCAG CCCAGCCCGT GTCTGAGTAG CGCTGAGGAT 
TCTGGGGTGG ATGAGGGACA GGGGAGCCCT TCGGAGATGG TCCATTCCTC GGAGTTCAGA 
GTAGACAACA ATCACCTGCT CCTGCTCATG ATCCACGTGT TCCGAGAAAA CGAAGAGCAG 
CTGTTCAAAA TGATCCGGAT GAGCACCGGG CACATGGAGG GCAACCTGCA GCTGCTGTAC 
GTGCTGCTCA CAGACTGCTA TGTCTACCTG CTCCGGAAAG GGGCCACAGA GAAGCCATAC 
CTGGTGGAAG AGGCCGTTTC TTACAATGAA CTTGACTATG TGTCGGTTGG CCTTGACCAG 
CAGACGGTGA AGCTGGTGTG CACCAACCGC AGGAAGCAGT TTCTGCTGGA CACGGCTGAT 
GTGGCGCTGG CTGAGTTCTT TTTGGCTTCT TTGAAGTCAG CCATGATCAA AGGCTGTCGA 
GAACCTCCCT ACCCCAGCAT CCTGACGGAT GCCACCATGG AGAAGCTGGC ACTGGCCAAA 
TTTGTGGCCC AAGAATCGAA GTGTGAGGCA TCTGCTGTCA CCGTGCGCTT CTACGGCCTT 
GTGCACTGGG AGGACCCCAC AGACGAGTCC CTGGGCCCCA CGCCCTGCCA CTGCTCACCC 
CCCGAGGGCA CCATCACCAA AGAAGGCATG CTGCACTACA AGGCGGGCAC CTCCTACCTG 
GGCAAGGAAC ACTGGAAGAC GTGCTTCGTG GTGCTCAGCA ACGGGATCCT CTACCAGTAC 
CCGGACCGCA CCGACGTCAT CCCTCTGCTC TCGGTGAACA TGGGGGGGGA GCAGTGCGGT 
GGCTGCCGGA GAGCCAACAC CACGGATCGG CCCCACGCCT TCCAGGTCAT TCTCTCCGAC 
CGGCCCTGCC TGGAGCTAAG TGCCGAGAGC GAGGCCGAGA TGGCCGAGTG GATGCAGCAT 
CTCTGCCAGG CTGTGTCCAA AGGGGTCATC CCCCAGGGCG TAGCTCCCAG CCCCTGCATA 
CCCTGCTGCC TGGTCCTCAC GGATGACCGC CTCTTTACGT GCCATGAGGA TTGCCAGACC 
AGCTTCTTCC GCTCTTTGGG CACAGCCAAG CTGGGCGACA TCAGCGCCGT CTCCACCGAG 
CCGGGCAAGG AGTACTGCGT CTTGGAGTTC TCCCAGGACA GCCAGCAGCT CCTCCCGCCC 
TGGGTCATCT ACCTGAGCTG CACTTCTGAA CTGGACCGAT TGCTGTCTGC ACTGAACTCT 
GGGTGGAAAA CCATCTATCA GGTGGACCTC CCCCACACGG CGATCCAGGA AGCCTCCAAC 
AAGAAGAAAT TCGAGGATGC CTTGAGCCTC ATCCACAGCG CCTGGCAGCG GAGCGACAGT 
CTCTGCCGCG GCCGAGCCTC CCGAGACCCC TGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHM2 ( XM_017000758.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856247.1 Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu87071
Clone ID Related Accession (Same CDS sequence)	XM_017000758.1
Accession Version	XM_017000758.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3039bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family M member 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCAGA GCTGCATCCA GCAGGTTGGG GCCTGTATGC ACCCTAGCCA GGATGGAGTG 
GGAAGGAAGT GCGCAATTCT GACTCCACAA ACACCTTTGT TGCAGAGCTA TTTTGCTGCA 
TGTGAGGATG AGATCCCTGC CATCCGGAAC CATGACAAGG TCCTACAGCG TCTGTGTGAG 
CACCTGGACC ACGCCCTGCT GTACGGACTG CAAGACCTCT CCTCTGGCTA CTGGGTGCTC 
GTGGTGCATT TTACTCGGAG AGAGGCCATC AAGCAGATCG AGGTGCTGCA GCACGTGGCC 
ACCAACCTGG GGCGCAGCCG TGCCTGGCTG TACCTGGCCC TCAACGAGAA CTCCTTGGAG 
AGCTACCTGC GGTTGTTCCA GGAGAACCTG GGCCTGCTGC ATAAGTACTA CGTCAAGAAT 
GCCCTGGTCT GCAGCCACGA TCACCTGACG CTCTTCCTGA CCTTGGTGTC CGGGCTAGAG 
TTCATTCGTT TCGAGCTGGA TCTGGATGCC CCTTACCTAG ACCTGGCCCC CTACATGCCC 
GACTACTACA AACCTCAGTA CCTGCTGGAC TTTGAAGACC GCCTTCCCAG CTCGGTCCAC 
GGCTCAGACA GTCTGTCCCT CAACTCTTTC AACTCCGTCA CCTCCACCAA CCTGGAGTGG 
GATGACAGTG CGATTGCCCC ATCTAGTGAG GATGGAGACC TCACAGACAC GGTCAGTGGT 
CCCCGCTCCA CAGCCTCCGA CCTGACCAGC AGCAAGGCCT CCACCAGGAG CCCCACCCAG 
CGCCAGAACC CCTTCAACGA GGAGCCGGCA GAGACTGTGT CCTCCTCTGA CACCACCCCC 
GTGCACACCA CCTCTCAGGA GAAGGAGGAG GCCCAGGCCC TGGACCCGCC GGATGCCTGC 
ACGGAGCTCG AGGTCATCAG GGTCACCAAG AAGAAGAAAA TTGGCAAGAA GAAAAAGAGC 
AGATCAGATG AGGAGGCAAG TCCACTCCAC CCCGCCTGCA GCCAGAAGAA ATGTGCCAAG 
CAGGGGGACG GTGACAGCCG CAACGGCAGC CCAAGCCTTG GGCGGGACTC GCCAGACACT 
ATGCTTGCCT CCCCCCAGGA GGAGGGAGAG GGGCCGAGCA GCACCACGGA GAGCAGCGAG 
CGCTCCGAGC CGGGCCTGCT GATCCCTGAG ATGAAGGACA CCTCCATGGA GCGCTTGGGG 
CAGCCCCTGA GCAAGGTTAT CGACCAGCTC AACGGGCAGC TGGACCCCAG CACCTGGTGC 
TCCCGTGCTG AGCCCCCAGA CCAGTCCTTT CGGACCGGCT CTCCCGGGGA TGCCCCGGAG 
AGGCCGCCGC TTTGCGACTT TAGTGAGGGG CTTTCAGCCC CAATGGACTT CTACCGCTTT 
ACCGTCGAGA GTCCAAGCAC TGTTACATCA GGTGGCGGCC ACCATGACCC TGCAGGGCTT 
GGCCAACCGC TGCATGTTCC TAGTAGCCCT GAGGCTGCTG GCCAAGAAGA AGAGGGAGGA 
GGAGGAGAGG GACAGACGCC TCGGCCCCTA GAGGATACCA CGAGGGAGGC TCAGGAGCTG 
GAGGCCCAGC TGTCCCTGGT CAGGGAGGGG CCTGTGTCTG AGCCAGAGCC TGGGACCCAG 
GAGGTTCTCT GCCAGCTCAA GCGAGACCAG CCCAGCCCGT GTCTGAGTAG CGCTGAGGAT 
TCTGGGGTGG ATGAGGGACA GGGGAGCCCT TCGGAGATGG TCCATTCCTC GGAGTTCAGA 
GTAGACAACA ATCACCTGCT CCTGCTCATG ATCCACGTGT TCCGAGAAAA CGAAGAGCAG 
CTGTTCAAAA TGATCCGGAT GAGCACCGGG CACATGGAGG GCAACCTGCA GCTGCTGTAC 
GTGCTGCTCA CAGACTGCTA TGTCTACCTG CTCCGGAAAG GGGCCACAGA GAAGCCATAC 
CTGGTGGAAG AGGCCGTTTC TTACAATGAA CTTGACTATG TGTCGGTTGG CCTTGACCAG 
CAGACGGTGA AGCTGGTGTG CACCAACCGC AGGAAGCAGT TTCTGCTGGA CACGGCTGAT 
GTGGCGCTGG CTGAGTTCTT TTTGGCTTCT TTGAAGTCAG CCATGATCAA AGGCTGTCGA 
GAACCTCCCT ACCCCAGCAT CCTGACGGAT GCCACCATGG AGAAGCTGGC ACTGGCCAAA 
TTTGTGGCCC AAGAATCGAA GTGTGAGGCA TCTGCTGTCA CCGTGCGCTT CTACGGCCTT 
GTGCACTGGG AGGACCCCAC AGACGAGTCC CTGGGCCCCA CGCCCTGCCA CTGCTCACCC 
CCCGAGGGCA CCATCACCAA AGAAGGCATG CTGCACTACA AGGCGGGCAC CTCCTACCTG 
GGCAAGGAAC ACTGGAAGAC GTGCTTCGTG GTGCTCAGCA ACGGGATCCT CTACCAGTAC 
CCGGACCGCA CCGACGTCAT CCCTCTGCTC TCGGTGAACA TGGGGGGGGA GCAGTGCGGT 
GGCTGCCGGA GAGCCAACAC CACGGATCGG CCCCACGCCT TCCAGGTCAT TCTCTCCGAC 
CGGCCCTGCC TGGAGCTAAG TGCCGAGAGC GAGGCCGAGA TGGCCGAGTG GATGCAGCAT 
CTCTGCCAGG CTGTGTCCAA AGGGGTCATC CCCCAGGGCG TAGCTCCCAG CCCCTGCATA 
CCCTGCTGCC TGGTCCTCAC GGATGACCGC CTCTTTACGT GCCATGAGGA TTGCCAGACC 
AGCTTCTTCC GCTCTTTGGG CACAGCCAAG CTGGGCGACA TCAGCGCCGT CTCCACCGAG 
CCGGGCAAGG AGTACTGCGT CTTGGAGTTC TCCCAGGACA GCCAGCAGCT CCTCCCGCCC 
TGGGTCATCT ACCTGAGCTG CACTTCTGAA CTGGACCGAT TGCTGTCTGC ACTGAACTCT 
GGGTGGAAAA CCATCTATCA GGTGGACCTC CCCCACACGG CGATCCAGGA AGCCTCCAAC 
AAGAAGAAAT TCGAGGATGC CTTGAGCCTC ATCCACAGCG CCTGGCAGCG GAGCGACAGT 
CTCTGCCGCG GCCGAGCCTC CCGAGACCCC TGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856247.1
CDS	96..3134
Translation	MNQSCIQQVGACMHPSQDGVGRKCAILTPQTPLLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC

Target ORF information:

RefSeq Version	XM_017000758.1
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RUN domain containing M2 (PLEKHM2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000758.1

ORF Insert Sequence:

ATGAACCAGA GCTGCATCCA GCAGGTTGGG GCCTGTATGC ACCCTAGCCA GGATGGAGTG 
GGAAGGAAGT GCGCAATTCT GACTCCACAA ACACCTTTGT TGCAGAGCTA TTTTGCTGCA 
TGTGAGGATG AGATCCCTGC CATCCGGAAC CATGACAAGG TCCTACAGCG TCTGTGTGAG 
CACCTGGACC ACGCCCTGCT GTACGGACTG CAAGACCTCT CCTCTGGCTA CTGGGTGCTC 
GTGGTGCATT TTACTCGGAG AGAGGCCATC AAGCAGATCG AGGTGCTGCA GCACGTGGCC 
ACCAACCTGG GGCGCAGCCG TGCCTGGCTG TACCTGGCCC TCAACGAGAA CTCCTTGGAG 
AGCTACCTGC GGTTGTTCCA GGAGAACCTG GGCCTGCTGC ATAAGTACTA CGTCAAGAAT 
GCCCTGGTCT GCAGCCACGA TCACCTGACG CTCTTCCTGA CCTTGGTGTC CGGGCTAGAG 
TTCATTCGTT TCGAGCTGGA TCTGGATGCC CCTTACCTAG ACCTGGCCCC CTACATGCCC 
GACTACTACA AACCTCAGTA CCTGCTGGAC TTTGAAGACC GCCTTCCCAG CTCGGTCCAC 
GGCTCAGACA GTCTGTCCCT CAACTCTTTC AACTCCGTCA CCTCCACCAA CCTGGAGTGG 
GATGACAGTG CGATTGCCCC ATCTAGTGAG GATGGAGACC TCACAGACAC GGTCAGTGGT 
CCCCGCTCCA CAGCCTCCGA CCTGACCAGC AGCAAGGCCT CCACCAGGAG CCCCACCCAG 
CGCCAGAACC CCTTCAACGA GGAGCCGGCA GAGACTGTGT CCTCCTCTGA CACCACCCCC 
GTGCACACCA CCTCTCAGGA GAAGGAGGAG GCCCAGGCCC TGGACCCGCC GGATGCCTGC 
ACGGAGCTCG AGGTCATCAG GGTCACCAAG AAGAAGAAAA TTGGCAAGAA GAAAAAGAGC 
AGATCAGATG AGGAGGCAAG TCCACTCCAC CCCGCCTGCA GCCAGAAGAA ATGTGCCAAG 
CAGGGGGACG GTGACAGCCG CAACGGCAGC CCAAGCCTTG GGCGGGACTC GCCAGACACT 
ATGCTTGCCT CCCCCCAGGA GGAGGGAGAG GGGCCGAGCA GCACCACGGA GAGCAGCGAG 
CGCTCCGAGC CGGGCCTGCT GATCCCTGAG ATGAAGGACA CCTCCATGGA GCGCTTGGGG 
CAGCCCCTGA GCAAGGTTAT CGACCAGCTC AACGGGCAGC TGGACCCCAG CACCTGGTGC 
TCCCGTGCTG AGCCCCCAGA CCAGTCCTTT CGGACCGGCT CTCCCGGGGA TGCCCCGGAG 
AGGCCGCCGC TTTGCGACTT TAGTGAGGGG CTTTCAGCCC CAATGGACTT CTACCGCTTT 
ACCGTCGAGA GTCCAAGCAC TGTTACATCA GGTGGCGGCC ACCATGACCC TGCAGGGCTT 
GGCCAACCGC TGCATGTTCC TAGTAGCCCT GAGGCTGCTG GCCAAGAAGA AGAGGGAGGA 
GGAGGAGAGG GACAGACGCC TCGGCCCCTA GAGGATACCA CGAGGGAGGC TCAGGAGCTG 
GAGGCCCAGC TGTCCCTGGT CAGGGAGGGG CCTGTGTCTG AGCCAGAGCC TGGGACCCAG 
GAGGTTCTCT GCCAGCTCAA GCGAGACCAG CCCAGCCCGT GTCTGAGTAG CGCTGAGGAT 
TCTGGGGTGG ATGAGGGACA GGGGAGCCCT TCGGAGATGG TCCATTCCTC GGAGTTCAGA 
GTAGACAACA ATCACCTGCT CCTGCTCATG ATCCACGTGT TCCGAGAAAA CGAAGAGCAG 
CTGTTCAAAA TGATCCGGAT GAGCACCGGG CACATGGAGG GCAACCTGCA GCTGCTGTAC 
GTGCTGCTCA CAGACTGCTA TGTCTACCTG CTCCGGAAAG GGGCCACAGA GAAGCCATAC 
CTGGTGGAAG AGGCCGTTTC TTACAATGAA CTTGACTATG TGTCGGTTGG CCTTGACCAG 
CAGACGGTGA AGCTGGTGTG CACCAACCGC AGGAAGCAGT TTCTGCTGGA CACGGCTGAT 
GTGGCGCTGG CTGAGTTCTT TTTGGCTTCT TTGAAGTCAG CCATGATCAA AGGCTGTCGA 
GAACCTCCCT ACCCCAGCAT CCTGACGGAT GCCACCATGG AGAAGCTGGC ACTGGCCAAA 
TTTGTGGCCC AAGAATCGAA GTGTGAGGCA TCTGCTGTCA CCGTGCGCTT CTACGGCCTT 
GTGCACTGGG AGGACCCCAC AGACGAGTCC CTGGGCCCCA CGCCCTGCCA CTGCTCACCC 
CCCGAGGGCA CCATCACCAA AGAAGGCATG CTGCACTACA AGGCGGGCAC CTCCTACCTG 
GGCAAGGAAC ACTGGAAGAC GTGCTTCGTG GTGCTCAGCA ACGGGATCCT CTACCAGTAC 
CCGGACCGCA CCGACGTCAT CCCTCTGCTC TCGGTGAACA TGGGGGGGGA GCAGTGCGGT 
GGCTGCCGGA GAGCCAACAC CACGGATCGG CCCCACGCCT TCCAGGTCAT TCTCTCCGAC 
CGGCCCTGCC TGGAGCTAAG TGCCGAGAGC GAGGCCGAGA TGGCCGAGTG GATGCAGCAT 
CTCTGCCAGG CTGTGTCCAA AGGGGTCATC CCCCAGGGCG TAGCTCCCAG CCCCTGCATA 
CCCTGCTGCC TGGTCCTCAC GGATGACCGC CTCTTTACGT GCCATGAGGA TTGCCAGACC 
AGCTTCTTCC GCTCTTTGGG CACAGCCAAG CTGGGCGACA TCAGCGCCGT CTCCACCGAG 
CCGGGCAAGG AGTACTGCGT CTTGGAGTTC TCCCAGGACA GCCAGCAGCT CCTCCCGCCC 
TGGGTCATCT ACCTGAGCTG CACTTCTGAA CTGGACCGAT TGCTGTCTGC ACTGAACTCT 
GGGTGGAAAA CCATCTATCA GGTGGACCTC CCCCACACGG CGATCCAGGA AGCCTCCAAC 
AAGAAGAAAT TCGAGGATGC CTTGAGCCTC ATCCACAGCG CCTGGCAGCG GAGCGACAGT 
CTCTGCCGCG GCCGAGCCTC CCGAGACCCC TGGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction.
Human molecular genetics24(25)7227-40(2015 Dec)
Muhammad E,Levitas A,Singh SR,Braiman A,Ofir R,Etzion S,Sheffield VC,Etzion Y,Carrier L,Parvari R

BORC, a multisubunit complex that regulates lysosome positioning.
Developmental cell33(2)176-88(2015 Apr)
Pu J,Schindler C,Jia R,Jarnik M,Backlund P,Bonifacino JS

Structural basis for kinesin-1:cargo recognition.
Science (New York, N.Y.)340(6130)356-9(2013 Apr)
Pernigo S,Lamprecht A,Steiner RA,Dodding MP

Salmonella inhibits retrograde trafficking of mannose-6-phosphate receptors and lysosome function.
Science (New York, N.Y.)338(6109)963-7(2012 Nov)
McGourty K,Thurston TL,Matthews SA,Pinaud L,Mota LJ,Holden DW

Arl8 and SKIP act together to link lysosomes to kinesin-1.
Developmental cell21(6)1171-8(2011 Dec)
Rosa-Ferreira C,Munro S

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PLEKHM2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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