RT1-Bb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	RT1-Bb
Entrez Gene ID	309622
Full Name	RT1 class II, locus Bb
Synonyms	Bb,RT1.B
General protein information	Preferred Names RT1 class II, locus Bb Names rano class II histocompatibility antigen, B-1 beta chain MHC class II antigen B beta chain RT1 class II histocompatibility antigen, B-1 beta chain RT1.B-beta(1) RT1.Bbeta 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	may play a role in antigen presentation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004084.2	NP_001004084.1	rano class II histocompatibility antigen, B-1 beta chain precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BLA-DQB	NP_001029840.2
Canis lupus familiaris (dog)	LOC100856137	XP_003639463.1
Canis lupus familiaris (dog)	DLA-DQB1	NP_001014403.1
Bos taurus (cattle)	BOLA-DQB	NP_001012694.2
Rattus norvegicus (Norway rat)	RT1-Bb	NP_001004084.1
	MAMU-DQB1	NP_001127769.1
Bos taurus (cattle)	LA-DQB	NP_001074392.1
Xenopus tropicalis (tropical clawed frog)	hla-drb1	NP_001039259.1
Homo sapiens (human)	HLA-DQB1	NP_001230890.1
Pan troglodytes (chimpanzee)	LOC100616520	XP_003339166.1
Mus musculus (house mouse)	H2-Ab1	NP_996988.2

Gene Ontology
Bibliography

Related articles in PubMed

Comprehensive investigating of cytokine and receptor related genes variants in patients with chronic hepatitis B virus infection.
Yu F, Ma N, Zhang X, Tian S, Geng L, Xu W, Wang M, Jia Y, Liu X, Ma J, Quan Y, Zhang C, Guo L, An W, Liu D
Cytokine10310-14(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results of this study indicated that MHC genes might contribute to the difference in pain sensitivity
Title: The major histocompatibility complex genes impact pain response in DA and DA.1U rats.

MHC class II is considered to be involved in the initiation of PS-induced hepatic fibrosis in rats.
Title: MHC class II-related genes expression in porcine-serum-induced rat hepatic fibrosis.

The following RT1-Bb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RT1-Bb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12899	NM_001004084.2 Latest version!	Rattus norvegicus RT1 class II, locus Bb (RT1-Bb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RT1-Bb ( NM_001004084.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001004084.1 Rattus norvegicus RT1 class II, locus Bb (RT1-Bb), mRNA.

Price & Availability↑

CloneID	ORa12899
Clone ID Related Accession (Same CDS sequence)	NM_001004084.2
Accession Version	NM_001004084.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Rattus norvegicus(Norway rat)
Product	rano class II histocompatibility antigen, B-1 beta chain precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB313071.1 and BC079121.1. On Sep 18, 2009 this sequence version replaced NM_001004084.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079121.1, X56596.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689594 [ECO:0000348] ##Evidence-Data-END##

ATGGCTCTGC AGACCCCCAG CTTCCTCCTC CCGGCAGCTG TGGTTGTGCT GATGGTGCTG 
AGCAGCCCAG GGACTGAGGG CAGAGACTCC CCAAGGGATT TCGTATTCCA GTTCAAGGGC 
CTGTGCTACT ACACCAACGG GACGCAGCGC ATACGGCTCG TGATCAGATA CATCTACAAC 
CGGGAGGAGT ACGTGCGCTT CGACAGCGAC GTGGGCGAGT TCCGCGCGCT GACCGAGCTG 
GGGCGGCCCT CAGCCGAGTA CTATAACAAA CAGTACCTGG AGCGGACGCG GGCCGAGCTG 
GACACGGTCT GCAGACACAA CTACGAGGAG ACGGAGGTCC CCACCTCCCT GCGGCGGCTT 
GAGCAGCCCA ATGTGGCCAT CTCCCTGTCC AGGACAGAGG CCCTCAACCA CCACAACTTG 
CTGGTCTGCT CAGTGACAGA TTTCTACCCA GCCCAGATCA AAGTGCGCTG GTTCCGGAAT 
GGCCAGGAGG AGACGGCGGG GGTCGTGTCC ACACAGCTTA TTAGGAACGG GGACTGGACC 
TTCCAGATCC TGGTCATGCT GGAGATGACG CCTCAGCGGG GAGAGGTGTA CATCTGCCAT 
GTTGACCACC CCAGCCTCGA GAGCCCCGTC ACAGTGGAGT GGCGGGCACA GTCCGAGTCT 
GCCCAGAGCA AGATGCTGAG CGGCATCGGG GGCTTTGTGC TGGGGGTGAT CTTCCTCGGG 
CTTGGCCTTT TCATCCGTCA CAAGCGTCAG AAAGGACCTC GGGGGCCTCC TCCAGCAGGG 
CTCCTACAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004084.1
CDS	69..860
Translation	MALQTPSFLLPAAVVVLMVLSSPGTEGRDSPRDFVFQFKGLCYYTNGTQRIRLVIRYIYNREEYVRFDSDVGEFRALTELGRPSAEYYNKQYLERTRAELDTVCRHNYEETEVPTSLRRLEQPNVAISLSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTQLIRNGDWTFQILVMLEMTPQRGEVYICHVDHPSLESPVTVEWRAQSESAQSKMLSGIGGFVLGVIFLGLGLFIRHKRQKGPRGPPPAGLLQ

Target ORF information:

RefSeq Version	NM_001004084.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RT1 class II, locus Bb (RT1-Bb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004084.2

ORF Insert Sequence:

ATGGCTCTGC AGACCCCCAG CTTCCTCCTC CCGGCAGCTG TGGTTGTGCT GATGGTGCTG 
AGCAGCCCAG GGACTGAGGG CAGAGACTCC CCAAGGGATT TCGTATTCCA GTTCAAGGGC 
CTGTGCTACT ACACCAACGG GACGCAGCGC ATACGGCTCG TGATCAGATA CATCTACAAC 
CGGGAGGAGT ACGTGCGCTT CGACAGCGAC GTGGGCGAGT TCCGCGCGCT GACCGAGCTG 
GGGCGGCCCT CAGCCGAGTA CTATAACAAA CAGTACCTGG AGCGGACGCG GGCCGAGCTG 
GACACGGTCT GCAGACACAA CTACGAGGAG ACGGAGGTCC CCACCTCCCT GCGGCGGCTT 
GAGCAGCCCA ATGTGGCCAT CTCCCTGTCC AGGACAGAGG CCCTCAACCA CCACAACTTG 
CTGGTCTGCT CAGTGACAGA TTTCTACCCA GCCCAGATCA AAGTGCGCTG GTTCCGGAAT 
GGCCAGGAGG AGACGGCGGG GGTCGTGTCC ACACAGCTTA TTAGGAACGG GGACTGGACC 
TTCCAGATCC TGGTCATGCT GGAGATGACG CCTCAGCGGG GAGAGGTGTA CATCTGCCAT 
GTTGACCACC CCAGCCTCGA GAGCCCCGTC ACAGTGGAGT GGCGGGCACA GTCCGAGTCT 
GCCCAGAGCA AGATGCTGAG CGGCATCGGG GGCTTTGTGC TGGGGGTGAT CTTCCTCGGG 
CTTGGCCTTT TCATCCGTCA CAAGCGTCAG AAAGGACCTC GGGGGCCTCC TCCAGCAGGG 
CTCCTACAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Comprehensive investigating of cytokine and receptor related genes variants in patients with chronic hepatitis B virus infection.
Cytokine10310-14(2017 Dec)
Yu F,Ma N,Zhang X,Tian S,Geng L,Xu W,Wang M,Jia Y,Liu X,Ma J,Quan Y,Zhang C,Guo L,An W,Liu D