Gene Symbol | DLA-DQB1 |
Entrez Gene ID | 474862 |
Full Name | major histocompatibility complex, class II, DQ beta 1 |
Synonyms | DLA-DQB |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » DLA-DQB1 cDNA ORF clone
Gene Symbol | DLA-DQB1 |
Entrez Gene ID | 474862 |
Full Name | major histocompatibility complex, class II, DQ beta 1 |
Synonyms | DLA-DQB |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001014381.1 | NP_001014403.1 | major histocompatibility complex, class II, DQ beta 1 precursor |
Bos taurus (cattle) | BLA-DQB | NP_001029840.2 |
Canis lupus familiaris (dog) | LOC100856137 | XP_003639463.1 |
Canis lupus familiaris (dog) | DLA-DQB1 | NP_001014403.1 |
Bos taurus (cattle) | BOLA-DQB | NP_001012694.2 |
Rattus norvegicus (Norway rat) | RT1-Bb | NP_001004084.1 |
MAMU-DQB1 | NP_001127769.1 | |
Bos taurus (cattle) | LA-DQB | NP_001074392.1 |
Xenopus tropicalis (tropical clawed frog) | hla-drb1 | NP_001039259.1 |
Homo sapiens (human) | HLA-DQB1 | NP_001230890.1 |
Pan troglodytes (chimpanzee) | LOC100616520 | XP_003339166.1 |
Mus musculus (house mouse) | H2-Ab1 | NP_996988.2 |
Association of DLA-DQB1 alleles with exocrine pancreatic insufficiency in Pembroke Welsh Corgis.
Evans JM, Tsai KL, Starr-Moss AN, Steiner JM, Clark LA
Animal genetics46(4)462-5(2015 Aug)
Molecular mechanism and cellular function of MHCII ubiquitination.
Oh J, Shin JS
Immunological reviews266(1)134-44(2015 Jul)
A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1.
Barrientos LS, Zapata G, Crespi JA, Posik DM, D?az S, It V, Peral-Garc?a P, Giovambattista G
Veterinary immunology and immunopathology156(3-4)205-10(2013 Dec)
MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs.
Jokinen P, Rusanen EM, Kennedy LJ, Lohi H
Veterinary immunology and immunopathology140(1-2)37-41(2011 Mar)
Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing.
Fliegner RA, Holloway SA, Lester S, McLure CA, Dawkins RL
Tissue antigens72(2)131-6(2008 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
we have identified both risk and protective alleles of DLA-DQB1 contributing to pancreatic insufficiency in Pembroke Welsh Corgis
Title: Association of DLA-DQB1 alleles with exocrine pancreatic insufficiency in Pembroke Welsh Corgis.
upstream regulatory regions (URRs) of the DLA-DRB, -DQA and -DQB genes were genotyped in 60 dogs
Title: A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1.
The haplotype DLADRB1* 01501/DQA1*00601/DQB1*00301 was significantly associated with chronic superficial keratitis (CSK) in German Shepherd dogs, and homozygosity of MHC class II increased risk for CSK.
Title: MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs.
The genomic matching technique enabled detection of DQB1 copy number, discrimination of the different class II haplotypes and the identification of new, possibly biologically relevant polymorphisms
Title: Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing.
Examining DQB1 variability in dogs, 7 promoter variants and 13 exon 2 alleles among 89 dogs were identified, including a previously unknown DQB1 exon 2 allele.
Title: Allelic combinations of promoter and exon 2 in DQB1 in dogs and wolves.
The following DLA-DQB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DLA-DQB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe34197 | |
Clone ID Related Accession (Same CDS sequence) | NM_001014381.1 | |
Accession Version | NM_001014381.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-21 | |
Organism | Canis lupus familiaris(dog) | |
Product | major histocompatibility complex, class II, DQ beta 1 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF043908.1. On Apr 4, 2005 this sequence version replaced XM_532097.1. ##Evidence-Data-START## Transcript exon combination :: AF043908.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCTGGGA AGATGACTCT GTGCATCCCC CGAGGCTTCT GGACAGCAGC TGTGATGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001014403.1 |
CDS | 1..810 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001014381.1 |
1 | ATGTCTGGGA AGATGACTCT GTGCATCCCC CGAGGCTTCT GGACAGCAGC TGTGATGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Association of DLA-DQB1 alleles with exocrine pancreatic insufficiency in Pembroke Welsh Corgis. |
Molecular mechanism and cellular function of MHCII ubiquitination. |
A study of the association between chronic superficial keratitis and polymorphisms in the upstream regulatory regions of DLA-DRB1, DLA-DQB1 and DLA-DQA1. |
MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. |
Evaluation of the class II region of the major histocompatibility complex of the greyhound with the genomic matching technique and sequence-based typing. |