| Gene Symbol | Dvl2 |
| Entrez Gene ID | 303251 |
| Full Name | dishevelled segment polarity protein 2 |
| Synonyms | Dvl-2 |
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
gRNAs
The following Dvl2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dvl2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa06415 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001172056.1 | |
| Accession Version | NM_001172056.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2211bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-09-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | segment polarity protein dishevelled homolog DVL-2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07029864.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCGGGCA GCAGCGCGGG GGGCGGTGGT GTAGGCGAGA CGAAGGTGAT TTACCATCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001165527.1 |
| CDS | 35..2245 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001172056.1 |
1 | ATGGCGGGCA GCAGCGCGGG GGGCGGTGGT GTAGGCGAGA CGAAGGTGAT TTACCATCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa33321 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006246715.3 | |
| Accession Version | XM_006246715.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | segment polarity protein dishevelled homolog DVL-2 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006246715.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCGGGCA GCAGCGCGGG GGGCGGTGGT GTAGGCGAGA CGAAGGTGAT TTACCATCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006246777.1 |
| CDS | 276..2474 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006246715.3 |
1 | ATGGCGGGCA GCAGCGCGGG GGGCGGTGGT GTAGGCGAGA CGAAGGTGAT TTACCATCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-?B pathway. |
The Wnt Signaling Antagonist Dapper1 Accelerates Dishevelled2 Degradation via Promoting Its Ubiquitination and Aggregate-induced Autophagy. |
Functional consequences of Wnt-induced dishevelled 2 phosphorylation in canonical and noncanonical Wnt signaling. |
Canonical Wnt signaling maintains the quiescent stage of hepatic stellate cells. |
