Cpsf2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cpsf2
Entrez Gene ID	299256
Full Name	cleavage and polyadenylation specific factor 2
General protein information	Preferred Names cleavage and polyadenylation specific factor 2 Names cleavage and polyadenylation specificity factor subunit 2 cleavage and polyadenylation specific factor 2, 100kDa
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q32

mRNA and Protein(s)

mRNA	Protein	Name
NM_001106753.1	NP_001100223.1	cleavage and polyadenylation specificity factor subunit 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CPSF2	XP_537353.2
Drosophila melanogaster (fruit fly)	Cpsf100	NP_651658.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002474	XP_312464.4
Caenorhabditis elegans (roundworm)	cpsf-2	NP_504822.1
Arabidopsis thaliana (thale cress)	CPSF100	NP_197776.1
Mus musculus (house mouse)	Cpsf2	NP_058552.1
Danio rerio (zebrafish)	cpsf2	NP_001002384.1
Bos taurus (cattle)	CPSF2	NP_787002.1
Homo sapiens (human)	CPSF2	NP_059133.1
Pan troglodytes (chimpanzee)	CPSF2	XP_001147277.1
Oryza sativa (rice)	Os09g0569400	NP_001063978.1
Xenopus tropicalis (tropical clawed frog)	cpsf2	NP_001120452.1
	CPSF2	XP_001092942.1
Rattus norvegicus (Norway rat)	Cpsf2	NP_001100223.1
Gallus gallus (chicken)	CPSF2	NP_001026379.1

Gene Ontology
Bibliography

Related articles in PubMed

Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors.
Gruber AR, Martin G, Keller W, Zavolan M
Wiley interdisciplinary reviews. RNA5(2)183-96(2014 Mar-Apr)

Pre-mRNA 3'-end processing complex assembly and function.
Chan S, Choi EA, Shi Y
Wiley interdisciplinary reviews. RNA2(3)321-35(2011 May-Jun)

The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA.
Laishram RS, Anderson RA
The EMBO journal29(24)4132-45(2010 Dec)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation.
Kolev NG, Yario TA, Benson E, Steitz JA
EMBO reports9(10)1013-8(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cpsf2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cpsf2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02131	NM_001106753.1 Latest version!	Rattus norvegicus cleavage and polyadenylation specific factor 2 (Cpsf2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$461.30 $659.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cpsf2 ( NM_001106753.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100223.1 Rattus norvegicus cleavage and polyadenylation specific factor 2 (Cpsf2), mRNA.

Price & Availability↑

CloneID	ORa02131
Clone ID Related Accession (Same CDS sequence)	NM_001106753.1
Accession Version	NM_001106753.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2349bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	cleavage and polyadenylation specificity factor subunit 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473982.1. On or before Oct 4, 2007 this sequence version replaced XM_216766.4, XM_001066531.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGACATCTA TCATCAAGTT AACTACCCTC TCTGGGGTCC AAGAGGAGTC TGCTCTTTGC 
TATCTTCTCC AGGTTGATGA GTTTAGATTT TTGTTGGACT GTGGCTGGGA TGAACACTTC 
TCTGTGGACA TTATTGATTC CCTGAGGAAG CATGTTCACC AGATCGATGC AGTGCTCCTG 
TCTCACCCCG ACCCACTCCA CCTCGGTGCC CTCCCGTTCG CTGTGGGGAA GCTGGGTCTG 
AACTGTGCCA TCTATGCAAC AATTCCTGTT TATAAAATGG GCCAGATGTT CATGTACGAT 
CTTTATCAGT CTCGACACAA TACAGAAGAT TTTACCCTCT TTACATTGGA CGATGTGGAT 
GCAGCCTTTG ATAAAATACA GCAGCTAAAA TTCTCTCAGA TCGTGAACCT GAAAGGCAAA 
GGACACGGTT TGTCGATCAC ACCCCTGCCA GCTGGTCATA TGATAGGAGG AACAATATGG 
AAAATAGTCA AAGACGGAGA AGAAGAGATT GTTTATGCCG TGGACTTCAA CCACAAGAGG 
GAGATTCACC TAAATGGATG TTCCCTGGAA ATGCTAAGCA GACCCTCTCT GCTTATCACA 
GATTCATTTA ATGCTACTTA TGTGCAGCCT AGAAGGAAAC AGAGAGACGA GCAGCTCCTG 
ACAAACGTCC TGGAAACTCT TCGGGGCGAT GGGAATGTGC TCATAGCCGT GGACACAGCA 
GGCAGAGTTC TGGAGCTTGC TCAACTTCTT GATCAGATTT GGAGAACTAA AGACGCGGGG 
TTGGGCGTTT ATTCGCTGGC TCTCCTGAAC AACGTCAGTT ACAACGTGGT GGAGTTCTCT 
AAGTCACAGG TAGAATGGAT GAGTGATAAA TTGATGAGAT GTTTTGAAGA CAAGAGAAAT 
AACCCATTTC AGTTTCGCCA TCTCTCTCTG TGCCACGGTC TTTCTGACTT GGCTCGGGTT 
CCAAGCCCCA AAGTTGTACT TGCCAGTCAG CCTGACCTGG AGTGTGGATT CTCAAGGGAC 
CTCTTTATTC AGTGGTGTCA GGACCCTAAA AACTCAATCA TCCTAACTTA CAGGACAACT 
CCGGGAACCT TAGCACGTTT CTTAATTGAT AATCCTTCTG AGAAAGTTAC AGAAATAGAG 
CTGAGGAAAC GCGTGAAGCT TGAAGGGAAA GAACTTGAGG AATATGTGGA AAAAGAGAAA 
CTAAAGAAAG AAGCTGCTAA GAAACTGGAG CAGTCGAAAG AGGCAGACAT CGACTCCAGT 
GACGAGAGTG ACGTGGAGGA AGACGTCGAC CAGCCAACAG CTCACAAAAC GAAGCACGAC 
CTGATGATGA AGGGGGAAGG CAGCCGAAAA GGGAGCTTCT TCAAACAGGC CAAAAAGTCC 
TACCCCATGT TTCCTGCCCC AGAAGAAAGG ATTAAATGGG ACGAGTATGG AGAGATCATC 
AAACCAGAAG ATTTCTTAGT GCCAGAACTT CAGGCTACTG AAGAAGAGAA AAGCAAATTA 
GAATCCGGCT TGACAAATGG AGAGGAACCC ATGGATCAGG ACCTGTCTGA TGTTCCCACC 
AAGTGTGTTT CTGCAACAGA GTCTATTGAG ATAAAAGCCA GAGTTACTTA CATAGACTAC 
GAAGGACGCT CCGATGGAGA CTCCATTAAA AAGATCATCA ATCAGATGAA ACCACGGCAG 
CTGATCATTG TCCACGGCCC ACCAGAGGCC AGTCAGGATC TGGCTGAGTG CTGCCGCGCA 
TTTGGTGGGA AAGATATCAA AGTGTACATG CCAAAGCTGC ACGAGACAGT CGATGCCACC 
AGCGAGACAC ATATCTACCA GGTAAGATTA AAGGACTCAC TTGTCAGCTC GCTTCAGTTC 
TGTAAAGCGA AAGATGCTGA GTTAGCATGG ATAGACGGCG TCTTAGACAT GAGAGTCTCC 
AAAGTGGACA CGGGAGTTAT TTTAGAAGAA GGAGAACTCA AGGATGATGG AGAAGACTCT 
GAAATGCAAG TGGATGCTCC TTCAGATTCC AGTGTCATAG CCCAGCAGAA GGCCATGAAA 
AGTCTGTTTG GAGATGATGA GAAAGAGCTG GGTGAGGAGA GTGAGGTCAT CCCCACACTG 
GAGCCTTTGC CACCTCATGA GGTTCCCGGA CACCAGTCAG TTTTTATGAA TGAACCGAGA 
CTGTCTGACT TCAAGCAAGT TCTTTTGCGG GAAGGGATTC AAGCGGAATT TGTAGGGGGC 
GTACTTGTCT GCAACAATCA AGTAGCAGTC CGCAGAACAG AAACTGGACG CATCGGGCTA 
GAAGGCTGCC TTTGTCAAGA CTTTTATAGG ATACGAGACC TTTTATATGA ACAGTATGCC 
ATTGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100223.1
CDS	180..2528
Translation	MTSIIKLTTLSGVQEESALCYLLQVDEFRFLLDCGWDEHFSVDIIDSLRKHVHQIDAVLLSHPDPLHLGALPFAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAAFDKIQQLKFSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIVYAVDFNHKREIHLNGCSLEMLSRPSLLITDSFNATYVQPRRKQRDEQLLTNVLETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAGLGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHGLSDLARVPSPKVVLASQPDLECGFSRDLFIQWCQDPKNSIILTYRTTPGTLARFLIDNPSEKVTEIELRKRVKLEGKELEEYVEKEKLKKEAAKKLEQSKEADIDSSDESDVEEDVDQPTAHKTKHDLMMKGEGSRKGSFFKQAKKSYPMFPAPEERIKWDEYGEIIKPEDFLVPELQATEEEKSKLESGLTNGEEPMDQDLSDVPTKCVSATESIEIKARVTYIDYEGRSDGDSIKKIINQMKPRQLIIVHGPPEASQDLAECCRAFGGKDIKVYMPKLHETVDATSETHIYQVRLKDSLVSSLQFCKAKDAELAWIDGVLDMRVSKVDTGVILEEGELKDDGEDSEMQVDAPSDSSVIAQQKAMKSLFGDDEKELGEESEVIPTLEPLPPHEVPGHQSVFMNEPRLSDFKQVLLREGIQAEFVGGVLVCNNQVAVRRTETGRIGLEGCLCQDFYRIRDLLYEQYAIV

Target ORF information:

RefSeq Version	NM_001106753.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cleavage and polyadenylation specific factor 2 (Cpsf2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106753.1

ORF Insert Sequence:

ATGACATCTA TCATCAAGTT AACTACCCTC TCTGGGGTCC AAGAGGAGTC TGCTCTTTGC 
TATCTTCTCC AGGTTGATGA GTTTAGATTT TTGTTGGACT GTGGCTGGGA TGAACACTTC 
TCTGTGGACA TTATTGATTC CCTGAGGAAG CATGTTCACC AGATCGATGC AGTGCTCCTG 
TCTCACCCCG ACCCACTCCA CCTCGGTGCC CTCCCGTTCG CTGTGGGGAA GCTGGGTCTG 
AACTGTGCCA TCTATGCAAC AATTCCTGTT TATAAAATGG GCCAGATGTT CATGTACGAT 
CTTTATCAGT CTCGACACAA TACAGAAGAT TTTACCCTCT TTACATTGGA CGATGTGGAT 
GCAGCCTTTG ATAAAATACA GCAGCTAAAA TTCTCTCAGA TCGTGAACCT GAAAGGCAAA 
GGACACGGTT TGTCGATCAC ACCCCTGCCA GCTGGTCATA TGATAGGAGG AACAATATGG 
AAAATAGTCA AAGACGGAGA AGAAGAGATT GTTTATGCCG TGGACTTCAA CCACAAGAGG 
GAGATTCACC TAAATGGATG TTCCCTGGAA ATGCTAAGCA GACCCTCTCT GCTTATCACA 
GATTCATTTA ATGCTACTTA TGTGCAGCCT AGAAGGAAAC AGAGAGACGA GCAGCTCCTG 
ACAAACGTCC TGGAAACTCT TCGGGGCGAT GGGAATGTGC TCATAGCCGT GGACACAGCA 
GGCAGAGTTC TGGAGCTTGC TCAACTTCTT GATCAGATTT GGAGAACTAA AGACGCGGGG 
TTGGGCGTTT ATTCGCTGGC TCTCCTGAAC AACGTCAGTT ACAACGTGGT GGAGTTCTCT 
AAGTCACAGG TAGAATGGAT GAGTGATAAA TTGATGAGAT GTTTTGAAGA CAAGAGAAAT 
AACCCATTTC AGTTTCGCCA TCTCTCTCTG TGCCACGGTC TTTCTGACTT GGCTCGGGTT 
CCAAGCCCCA AAGTTGTACT TGCCAGTCAG CCTGACCTGG AGTGTGGATT CTCAAGGGAC 
CTCTTTATTC AGTGGTGTCA GGACCCTAAA AACTCAATCA TCCTAACTTA CAGGACAACT 
CCGGGAACCT TAGCACGTTT CTTAATTGAT AATCCTTCTG AGAAAGTTAC AGAAATAGAG 
CTGAGGAAAC GCGTGAAGCT TGAAGGGAAA GAACTTGAGG AATATGTGGA AAAAGAGAAA 
CTAAAGAAAG AAGCTGCTAA GAAACTGGAG CAGTCGAAAG AGGCAGACAT CGACTCCAGT 
GACGAGAGTG ACGTGGAGGA AGACGTCGAC CAGCCAACAG CTCACAAAAC GAAGCACGAC 
CTGATGATGA AGGGGGAAGG CAGCCGAAAA GGGAGCTTCT TCAAACAGGC CAAAAAGTCC 
TACCCCATGT TTCCTGCCCC AGAAGAAAGG ATTAAATGGG ACGAGTATGG AGAGATCATC 
AAACCAGAAG ATTTCTTAGT GCCAGAACTT CAGGCTACTG AAGAAGAGAA AAGCAAATTA 
GAATCCGGCT TGACAAATGG AGAGGAACCC ATGGATCAGG ACCTGTCTGA TGTTCCCACC 
AAGTGTGTTT CTGCAACAGA GTCTATTGAG ATAAAAGCCA GAGTTACTTA CATAGACTAC 
GAAGGACGCT CCGATGGAGA CTCCATTAAA AAGATCATCA ATCAGATGAA ACCACGGCAG 
CTGATCATTG TCCACGGCCC ACCAGAGGCC AGTCAGGATC TGGCTGAGTG CTGCCGCGCA 
TTTGGTGGGA AAGATATCAA AGTGTACATG CCAAAGCTGC ACGAGACAGT CGATGCCACC 
AGCGAGACAC ATATCTACCA GGTAAGATTA AAGGACTCAC TTGTCAGCTC GCTTCAGTTC 
TGTAAAGCGA AAGATGCTGA GTTAGCATGG ATAGACGGCG TCTTAGACAT GAGAGTCTCC 
AAAGTGGACA CGGGAGTTAT TTTAGAAGAA GGAGAACTCA AGGATGATGG AGAAGACTCT 
GAAATGCAAG TGGATGCTCC TTCAGATTCC AGTGTCATAG CCCAGCAGAA GGCCATGAAA 
AGTCTGTTTG GAGATGATGA GAAAGAGCTG GGTGAGGAGA GTGAGGTCAT CCCCACACTG 
GAGCCTTTGC CACCTCATGA GGTTCCCGGA CACCAGTCAG TTTTTATGAA TGAACCGAGA 
CTGTCTGACT TCAAGCAAGT TCTTTTGCGG GAAGGGATTC AAGCGGAATT TGTAGGGGGC 
GTACTTGTCT GCAACAATCA AGTAGCAGTC CGCAGAACAG AAACTGGACG CATCGGGCTA 
GAAGGCTGCC TTTGTCAAGA CTTTTATAGG ATACGAGACC TTTTATATGA ACAGTATGCC 
ATTGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors.
Wiley interdisciplinary reviews. RNA5(2)183-96(2014 Mar-Apr)
Gruber AR,Martin G,Keller W,Zavolan M

Pre-mRNA 3'-end processing complex assembly and function.
Wiley interdisciplinary reviews. RNA2(3)321-35(2011 May-Jun)
Chan S,Choi EA,Shi Y

The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA.
The EMBO journal29(24)4132-45(2010 Dec)
Laishram RS,Anderson RA

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation.
EMBO reports9(10)1013-8(2008 Oct)
Kolev NG,Yario TA,Benson E,Steitz JA

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Cpsf2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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