Tardbp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tardbp
Entrez Gene ID	298648
Full Name	TAR DNA binding protein
Synonyms	Tdp-43
General protein information	Preferred Names TAR DNA binding protein Names TAR DNA-binding protein 43
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36

mRNA and Protein(s)

mRNA	Protein	Name
XM_006239382.3	XP_006239444.1	TAR DNA-binding protein 43 isoform X1
NM_001011979.2	NP_001011979.1	TAR DNA-binding protein 43
XM_008764234.2	XP_008762456.1	TAR DNA-binding protein 43 isoform X2
XM_008764236.2	XP_008762458.1	TAR DNA-binding protein 43 isoform X6
XM_006239385.3	XP_006239447.1	TAR DNA-binding protein 43 isoform X4
XM_006239386.3	XP_006239448.1	TAR DNA-binding protein 43 isoform X7
XM_006239384.3	XP_006239446.1	TAR DNA-binding protein 43 isoform X3
XM_008764235.2	XP_008762457.1	TAR DNA-binding protein 43 isoform X5

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	TBPH	NP_477399.1
Rattus norvegicus (Norway rat)	Tardbp	NP_001011979.1
Drosophila melanogaster (fruit fly)	CG7804	NP_001261874.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003497	XP_309663.5
Caenorhabditis elegans (roundworm)	tdp-1	NP_001254189.1
Danio rerio (zebrafish)	tardbpl	NP_938178.1

Gene Ontology
Bibliography

Related articles in PubMed

Temporal Expression of Mutant TDP-43 Correlates with Early Amyotrophic Lateral Sclerosis Phenotype and Motor Weakness.
Chen Q, Zhou J, Huang C, Huang B, Bi F, Zhou H, Xiao B
Current neurovascular research(2018 Jan)

Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity.
Woo JA, Liu T, Trotter C, Fang CC, De Narvaez E, LePochat P, Maslar D, Bukhari A, Zhao X, Deonarine A, Westerheide SD, Kang DE
Nature communications815558(2017 Jun)

Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons.
Gopal PP, Nirschl JJ, Klinman E, Holzbaur EL
Proceedings of the National Academy of Sciences of the United States of America114(12)E2466-E2475(2017 Mar)

Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in?vitro studies.
Jayakumar AR, Tong XY, Shamaladevi N, Barcelona S, Gaidosh G, Agarwal A, Norenberg MD
Journal of neurochemistry140(4)645-661(2017 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chronic traumatic encephalopathy induces increases in TDP-43 phosphorylation which contributes to defective neuronal integrity.
Title: Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in?vitro studies.

These results suggest that residues 274-353 are responsible for the conversion of TDP-43 to amyloid-like fibrils and that templated aggregation of TDP-43 by seeding with different peptides induces various types of TDP-43 pathologies, i.e. the peptides appear to act like prion strains.
Title: Templated Aggregation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Seeding with TDP-43 Peptide Fibrils.

This is the first evidence that TDP-43 might be involved in acute neuroinjury and TBI pathology
Title: Dual vulnerability of TDP-43 to calpain and caspase-3 proteolysis after neurotoxic conditions and traumatic brain injury.

TDP-43 pathogenesis is associated with simultaneous induction of neurotoxic genes and repression of neurotrophic genes in astrocytes
Title: Profiling the genes affected by pathogenic TDP-43 in astrocytes.

We now report that ALS-linked mutations in TDP-43 increase the size of neuronal TDP-43 granules in the dendritic arbor of rat hippocampal neurons. The mutations correspondingly reduce the granule density, movement, and mobility of TDP-43 granules.
Title: ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor.

The following Tardbp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tardbp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13365	NM_001011979.2 Latest version!	Rattus norvegicus TAR DNA binding protein (Tardbp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28891	XM_006239382.3 Latest version!	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa28892	XM_006239384.3 Latest version!	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28893	XM_006239385.3 Latest version!	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa28894	XM_006239386.3 Latest version!	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa45557	XM_008764234.2 Latest version!	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa45558	XM_008764235.2 Latest version!	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa45559	XM_008764236.2 Latest version!	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tardbp ( NM_001011979.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001011979.1 Rattus norvegicus TAR DNA binding protein (Tardbp), mRNA.

Price & Availability↑

CloneID	ORa13365
Clone ID Related Accession (Same CDS sequence)	NM_001011979.2
Accession Version	NM_001011979.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Rattus norvegicus(Norway rat)
Product	TAR DNA-binding protein 43
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI502405.1, BC083752.1, CF109817.1 and DV725863.1. On Jan 26, 2008 this sequence version replaced NM_001011979.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC083752.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGAAAATCT 
CCATTTGGGA GATCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011979.1
CDS	104..961
Translation	MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGKSPFGRS

Target ORF information:

RefSeq Version	NM_001011979.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAR DNA binding protein (Tardbp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011979.2

ORF Insert Sequence:

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGAAAATCT 
CCATTTGGGA GATCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tardbp ( XM_006239382.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239444.1 Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa28891
Clone ID Related Accession (Same CDS sequence)	XM_006239382.3
Accession Version	XM_006239382.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	TAR DNA-binding protein 43 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239382.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGTGGCTTTG GGAATCAGGG TGGGTTTGGT AACAGTAGAG GGGGTGGAGC TGGCTTGGGA 
AATAACCAGG GTGGTAATAT GGGTGGAGGG ATGAATTTTG GTGCTTTTAG CATTAATCCA 
GCGATGATGG CTGCAGCTCA GGCAGCGTTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA 
GCCAGCCAGC AGAACCAGTC AGGCCCATCT GGGAATAACC AAAGCCAGGG CAGCATGCAG 
AGGGAACCAA ATCAGGCTTT TGGTTCTGGA AATAACTCTT ACAGTGGTTC TAATTCTGGT 
GCCCCCCTTG GTTGGGGGTC AGCATCAAAT GCAGGATCAG GCAGTGGTTT TAATGGAGGC 
TTTGGCTCAA GCATGGATTC TAAATCCTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239444.1
CDS	277..1521
Translation	MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGGNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQSQGSMQREPNQAFGSGNNSYSGSNSGAPLGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM

Target ORF information:

RefSeq Version	XM_006239382.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239382.3

ORF Insert Sequence:

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGTGGCTTTG GGAATCAGGG TGGGTTTGGT AACAGTAGAG GGGGTGGAGC TGGCTTGGGA 
AATAACCAGG GTGGTAATAT GGGTGGAGGG ATGAATTTTG GTGCTTTTAG CATTAATCCA 
GCGATGATGG CTGCAGCTCA GGCAGCGTTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA 
GCCAGCCAGC AGAACCAGTC AGGCCCATCT GGGAATAACC AAAGCCAGGG CAGCATGCAG 
AGGGAACCAA ATCAGGCTTT TGGTTCTGGA AATAACTCTT ACAGTGGTTC TAATTCTGGT 
GCCCCCCTTG GTTGGGGGTC AGCATCAAAT GCAGGATCAG GCAGTGGTTT TAATGGAGGC 
TTTGGCTCAA GCATGGATTC TAAATCCTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tardbp ( XM_006239384.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239446.1 Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa28892
Clone ID Related Accession (Same CDS sequence)	XM_006239384.3
Accession Version	XM_006239384.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 897bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	TAR DNA-binding protein 43 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239384.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GTTCATCTCA TTTCAAATGT TTATGGAAGA AGCACTTCAT TGAAAGTAGT GCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239446.1
CDS	161..1057
Translation	MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPVHLISNVYGRSTSLKVVL

Target ORF information:

RefSeq Version	XM_006239384.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239384.3

ORF Insert Sequence:

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GTTCATCTCA TTTCAAATGT TTATGGAAGA AGCACTTCAT TGAAAGTAGT GCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tardbp ( XM_006239385.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239447.1 Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X6, mRNA.

Price & Availability↑

CloneID	ORa28893
Clone ID Related Accession (Same CDS sequence)	XM_006239385.3
Accession Version	XM_006239385.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	TAR DNA-binding protein 43 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239385.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGTTCATCTC 
ATTTCAAATG TTTATGGAAG AAGCACTTCA TTGAAAGTAG TGCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239447.1
CDS	261..1148
Translation	MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGVHLISNVYGRSTSLKVVL

Target ORF information:

RefSeq Version	XM_006239385.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239385.3

ORF Insert Sequence:

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGTTCATCTC 
ATTTCAAATG TTTATGGAAG AAGCACTTCA TTGAAAGTAG TGCTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tardbp ( XM_006239386.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006239448.1 Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X10, mRNA.

Price & Availability↑

CloneID	ORa28894
Clone ID Related Accession (Same CDS sequence)	XM_006239386.3
Accession Version	XM_006239386.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	TAR DNA-binding protein 43 isoform X7
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006239386.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGAATACTTC TGTCTACATG CTTTCTCATC CAAGAATTCG TCATCACGCT GCACAGGCTG 
CGTCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006239448.1
CDS	262..1170
Translation	MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGILLSTCFLIQEFVITLHRLRL

Target ORF information:

RefSeq Version	XM_006239386.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006239386.3

ORF Insert Sequence:

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGAATACTTC TGTCTACATG CTTTCTCATC CAAGAATTCG TCATCACGCT GCACAGGCTG 
CGTCTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tardbp ( XM_008764234.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008762456.1 Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa45557
Clone ID Related Accession (Same CDS sequence)	XM_008764234.2
Accession Version	XM_008764234.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 915bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	TAR DNA-binding protein 43 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764234.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGTGGCTTTG GGAATCAGGT TCATCTCATT TCAAATGTTT ATGGAAGAAG CACTTCATTG 
AAAGTAGTGC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008762456.1
CDS	262..1176
Translation	MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQVHLISNVYGRSTSLKVVL

Target ORF information:

RefSeq Version	XM_008764234.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764234.2

ORF Insert Sequence:

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGTGGCTTTG GGAATCAGGT TCATCTCATT TCAAATGTTT ATGGAAGAAG CACTTCATTG 
AAAGTAGTGC TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tardbp ( XM_008764235.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008762457.1 Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X8, mRNA.

Price & Availability↑

CloneID	ORa45558
Clone ID Related Accession (Same CDS sequence)	XM_008764235.2
Accession Version	XM_008764235.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 885bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	TAR DNA-binding protein 43 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764235.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGTGGCTTTG GGAATCAGGG AAAATCTCCA TTTGGGAGAT CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008762457.1
CDS	162..1046
Translation	MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGKSPFGRS

Target ORF information:

RefSeq Version	XM_008764235.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764235.2

ORF Insert Sequence:

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGTGGCTTTG GGAATCAGGG AAAATCTCCA TTTGGGAGAT CATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tardbp ( XM_008764236.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008762458.1 Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X9, mRNA.

Price & Availability↑

CloneID	ORa45559
Clone ID Related Accession (Same CDS sequence)	XM_008764236.2
Accession Version	XM_008764236.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	TAR DNA-binding protein 43 isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764236.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGAAAATCTC CATTTGGGAG ATCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008762458.1
CDS	160..1026
Translation	MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGKSPFGRS

Target ORF information:

RefSeq Version	XM_008764236.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TAR DNA binding protein (Tardbp), transcript variant X9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764236.2

ORF Insert Sequence:

ATGTCTGAAT ATATTCGGGT AACAGAAGAT GAGAATGATG AGCCCATTGA AATACCATCA 
GAAGACGATG GGACAGTGTT GCTGTCCACA GTTACAGCCC AGTTTCCAGG GGCGTGTGGC 
CTGCGCTACC GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGACTGGT GGAAGGAATT 
CTGCATGCCC CAGATGCTGG CTGGGGCAAT CTGGTCTATG TTGTCAACTA TCCCAAAGAT 
AACAAAAGGA AAATGGATGA GGCGGATGCT TCCTCTGCAG TGAAAGTGAA AAGAGCAGTC 
CAGAAGACAT CTGACCTCAT AGTGTTGGGT CTCCCCTGGA AAACAACAGA GCAGGACCTA 
AAAGACTACT TCAGTACTTT TGGAGAGGTT CTTATGGTTC AGGTCAAGAA AGATCTTAAA 
ACTGGTCACT CAAAAGGGTT TGGCTTTGTT CGATTTACGG AATATGAAAC TCAAGTGAAA 
GTAATGTCAC AGCGACATAT GATAGATGGG CGATGGTGTG ACTGTAAACT TCCAAATTCT 
AAGCAAAGCC CAGACGAGCC TTTGAGAAGC AGAAAGGTGT TTGTTGGACG TTGTACAGAG 
GACATGACTG CTGAAGAGCT TCAGCAGTTC TTCTGTCAGT ATGGAGAAGT GGTAGATGTC 
TTCATTCCCA AACCATTCAG AGCTTTTGCC TTTGTTACCT TTGCAGATGA TAAGGTTGCC 
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTGCATAT ATCCAATGCT 
GAACCTAAGC ATAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA 
GGAAAATCTC CATTTGGGAG ATCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Temporal Expression of Mutant TDP-43 Correlates with Early Amyotrophic Lateral Sclerosis Phenotype and Motor Weakness.
Current neurovascular research(2018 Jan)
Chen Q,Zhou J,Huang C,Huang B,Bi F,Zhou H,Xiao B

Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity.
Nature communications815558(2017 Jun)
Woo JA,Liu T,Trotter C,Fang CC,De Narvaez E,LePochat P,Maslar D,Bukhari A,Zhao X,Deonarine A,Westerheide SD,Kang DE

Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons.
Proceedings of the National Academy of Sciences of the United States of America114(12)E2466-E2475(2017 Mar)
Gopal PP,Nirschl JJ,Klinman E,Holzbaur EL

Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in?vitro studies.
Journal of neurochemistry140(4)645-661(2017 Feb)
Jayakumar AR,Tong XY,Shamaladevi N,Barcelona S,Gaidosh G,Agarwal A,Norenberg MD

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Tardbp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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