Canx cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Canx
Entrez Gene ID	29144
Full Name	calnexin
General protein information	Preferred Names calnexin Names calnexin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q22
Summary	calcium-binding protein that may serve to chaperone proteins from the ER to outer cellular membrane [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008767680.2	XP_008765902.1	calnexin isoform X1
XM_008767679.2	XP_008765901.1	calnexin isoform X1
NM_172008.2	NP_742005.1	calnexin precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CANX	NP_001099082.1
Mus musculus (house mouse)	Canx	NP_001103969.1
Drosophila melanogaster (fruit fly)	Cnx99A	NP_001036767.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005032	XP_313899.4
Oryza sativa (rice)	Os04g0402100	NP_001052692.1
Rattus norvegicus (Norway rat)	Canx	NP_742005.1
Danio rerio (zebrafish)	canx	NP_998613.1
Homo sapiens (human)	CANX	NP_001019820.1
Gallus gallus (chicken)	CANX	NP_001025791.2
Arabidopsis thaliana (thale cress)	CNX1	NP_200987.1
	CANX	XP_002804712.1
Canis lupus familiaris (dog)	CANX	NP_001003232.1
Drosophila melanogaster (fruit fly)	CG1924	NP_572788.2
Caenorhabditis elegans (roundworm)	cnx-1	NP_499176.1
Pan troglodytes (chimpanzee)	CANX	XP_518152.2
Drosophila melanogaster (fruit fly)	Cnx14D	NP_573131.1
Arabidopsis thaliana (thale cress)	AT5G07340	NP_001190249.1
Xenopus tropicalis (tropical clawed frog)	canx	NP_001005668.1

Gene Ontology
Bibliography

Related articles in PubMed

The Cacna1h mutation in the GAERS model of absence epilepsy enhances T-type Ca
Proft J, Rzhepetskyy Y, Lazniewska J, Zhang FX, Cain SM, Snutch TP, Zamponi GW, Weiss N
Scientific reports7(1)11513(2017 Sep)

Stratified analysis of lectin-like chaperones in the folding disease-related metabolic syndrome rat model.
Hirano M, Imagawa A, Totani K
Biochemical and biophysical research communications478(1)247-253(2016 09)

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
Urresti J, Ruiz-Meana M, Coccia E, Ar?valo JC, Castellano J, Fern?ndez-Sanz C, Galenkamp KM, Planells-Ferrer L, Moubarak RS, Llecha-Cano N, Reix S, Garc?a-Dorado D, Barneda-Zahonero B, Comella JX
The Journal of biological chemistry291(3)1221-34(2016 Jan)

Transmembrane and coiled-coil domain family 1 is a novel protein of the endoplasmic reticulum.
Zhang C, Kho YS, Wang Z, Chiang YT, Ng GK, Shaw PC, Wang Y, Qi RZ
PloS one9(1)e85206(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Therefore, these results indicate that obesity down-regulates CNX and CRT expressions and their activities and diabetes up-regulates the expressions and activities of CNX and CRT. Our findings clearly suggest that metabolic syndrome affects the lectin-like chaperones in the CNX/CRT cycle at both the activity and expression levels.
Title: Stratified analysis of lectin-like chaperones in the folding disease-related metabolic syndrome rat model.

calnexin localizes to the neuronal cell membrane & this recruitment is regulated in an NMDA receptor-dependent manner. immunoisolation of vesicles revealed co-localization of GluA2 and calnexin in post-ER intracellular membrane components.
Title: NMDA receptor-dependent recruitment of calnexin to the neuronal plasma membrane.

Transmembrane segments prevent surface expression of sodium channel Nav1.8 and promote calnexin-dependent channel degradation
Title: Transmembrane segments prevent surface expression of sodium channel Nav1.8 and promote calnexin-dependent channel degradation.

endoplasmic reticulum stress has effects on group VIA phospholipase A2 in beta cells that include tyrosine phosphorylation and increased association with calnexin
Title: Effects of endoplasmic reticulum stress on group VIA phospholipase A2 in beta cells include tyrosine phosphorylation and increased association with calnexin.

two new complementary roles for calcineurin in the regulation of the early UPR (Unfolded Protein Responses)
Title: Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs.

The following Canx gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Canx cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12945	NM_172008.2 Latest version!	Rattus norvegicus calnexin (Canx), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa33031	XM_008767680.2 Latest version!	Rattus norvegicus calnexin (Canx), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa33031	XM_008767679.2 Latest version!	Rattus norvegicus calnexin (Canx), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Canx ( NM_172008.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_742005.1 Rattus norvegicus calnexin (Canx), mRNA.

Price & Availability↑

CloneID	ORa12945
Clone ID Related Accession (Same CDS sequence)	NM_172008.2
Accession Version	NM_172008.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	calnexin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB586187.1, L18889.1, EV776124.1 and AABR07072099.1. On Jan 9, 2008 this sequence version replaced NM_172008.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ210638.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGGAAGGGA AGTGGTTACT GTGTTTGCTA CTGGTCCTTG GAACTGCAGC TATTCAGGCT 
CATGATGGAC ATGATGATGA CATGATTGAT ATTGAAGATG ATCTTGATGA TGTTATCGAA 
GAGGTAGAAG ATTCAAAATC TAAATCAGAT ACCAGCACTC CTCCATCTCC AAAGGTCACC 
TACAAAGCTC CAGTTCCAAC AGGGGAGGTT TATTTTGCTG ACTCCTTTGA CAGAGGGTCT 
CTGTCAGGGT GGATTTTATC TAAAGCCAAA AAAGACGACA CTGATGATGA AATTGCCAAA 
TATGACGGAA AGTGGGAGGT AGATGAAATG AAGGAAACAA AGCTTCCAGG TGATAAAGGA 
CTTGTATTGA TGTCTCGGGC CAAGCATCAT GCCATCTCTG CTAAACTGAA CAAGCCCTTC 
CTGTTTGATA CCAAGCCTCT CATTGTTCAG TATGAGGTTA ACTTTCAGAA TGGAATAGAA 
TGCGGTGGTG CCTACGTGAA GCTGCTATCC AAGACCTCAG AACTCAACCT GGATCAATTC 
CACGACAAGA CTCCGTATAC TATTATGTTT GGTCCAGATA AATGTGGAGA GGACTACAAA 
CTGCATTTCA TCTTTCGCCA CAAAAACCCC AAGACAGGTG TATATGAAGA AAAACATGCT 
AAGAGGCCAG ATGCAGATCT GAAGACCTAT TTCACTGACA AGAAAACACA TCTTTACACA 
TTAATCTTGA ATCCAGACAA TAGTTTTGAA ATATTAGTTG ACCAGTCTGT TGTGAACAGT 
GGAAACCTGC TAAATGACAT GACCCCTCCG GTAAACCCTT CACGTGAAAT TGAGGACCCA 
GAAGACCGGA AGCCTGAAGA TTGGGATGAA AGGCCCAAAA TAGCAGATCC AGATGCTGTC 
AAGCCAGATG ACTGGGATGA AGATGCCCCT TCTAAGATTC CAGATGAAGA GGCCACAAAG 
CCTGAAGGCT GGTTAGATGA TGAACCCGAG TATATTCCAG ACCCTGATGC AGAGAAACCA 
GAAGATTGGG ATGAGGATAT GGACGGAGAA TGGGAGGCTC CTCAGATTGC CAACCCTAAG 
TGTGAGTCCG CCCCTGGGTG TGGTGTCTGG CAGCGACCTA TGATTGACAA CCCCAATTAT 
AAGGGCAAAT GGAAGCCTCC TATGATTGAC AATCCTAACT ACCAGGGAAT CTGGAAACCA 
AGGAAAATAC CAAATCCAGA TTTCTTTGAA GACCTGGAAC CTTTTAGGAT GACTCCTTTC 
AGCGCTATTG GTTTGGAGCT CTGGTCCATG ACATCCGACA TCTTTTTTGA CAACTTTATC 
ATTAGTGGTG ACCGAAGAGT AGTTGATGAC TGGGCCAATG ATGGGTGGGG CCTGAAGAAA 
GCTGCTGATG GGGCTGCAGA GCCAGGTGTA GTGGGGCAGA TGCTGGAGGC AGCTGAAGAG 
CGTCCATGGC TTTGGGTGGT CTACATTCTG ACTGTAGCGT TGCCAGTGTT CCTTGTGATC 
CTCTTCTGCT GTTCTGGAAA GAAACAGTCC AATGCTATGG AGTACAAGAA GACAGATGCT 
CCCCAGCCAG ATGTGAAGGA CGAAGAAGGG AAGGAAGAAG AGAAGAACAA GGGAGATGAA 
GAGGAAGAAG AGGAGAAGCT TGAAGAGAAA CAGAAGAGTG ATGCTGAAGA AGATGGTGGC 
ACTGGCAGTC AAGATGAGGA AGATAGCAAG CCTAAAGCAG AGGAGGATGA AATTTTGAAC 
AGATCACCAA GAAACAGAAA GCCACGAAGA GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_742005.1
CDS	104..1879
Translation	MEGKWLLCLLLVLGTAAIQAHDGHDDDMIDIEDDLDDVIEEVEDSKSKSDTSTPPSPKVTYKAPVPTGEVYFADSFDRGSLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTSELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATKPEGWLDDEPEYIPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIISGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMLEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQSNAMEYKKTDAPQPDVKDEEGKEEEKNKGDEEEEEEKLEEKQKSDAEEDGGTGSQDEEDSKPKAEEDEILNRSPRNRKPRRE

Target ORF information:

RefSeq Version	NM_172008.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calnexin (Canx), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172008.2

ORF Insert Sequence:

ATGGAAGGGA AGTGGTTACT GTGTTTGCTA CTGGTCCTTG GAACTGCAGC TATTCAGGCT 
CATGATGGAC ATGATGATGA CATGATTGAT ATTGAAGATG ATCTTGATGA TGTTATCGAA 
GAGGTAGAAG ATTCAAAATC TAAATCAGAT ACCAGCACTC CTCCATCTCC AAAGGTCACC 
TACAAAGCTC CAGTTCCAAC AGGGGAGGTT TATTTTGCTG ACTCCTTTGA CAGAGGGTCT 
CTGTCAGGGT GGATTTTATC TAAAGCCAAA AAAGACGACA CTGATGATGA AATTGCCAAA 
TATGACGGAA AGTGGGAGGT AGATGAAATG AAGGAAACAA AGCTTCCAGG TGATAAAGGA 
CTTGTATTGA TGTCTCGGGC CAAGCATCAT GCCATCTCTG CTAAACTGAA CAAGCCCTTC 
CTGTTTGATA CCAAGCCTCT CATTGTTCAG TATGAGGTTA ACTTTCAGAA TGGAATAGAA 
TGCGGTGGTG CCTACGTGAA GCTGCTATCC AAGACCTCAG AACTCAACCT GGATCAATTC 
CACGACAAGA CTCCGTATAC TATTATGTTT GGTCCAGATA AATGTGGAGA GGACTACAAA 
CTGCATTTCA TCTTTCGCCA CAAAAACCCC AAGACAGGTG TATATGAAGA AAAACATGCT 
AAGAGGCCAG ATGCAGATCT GAAGACCTAT TTCACTGACA AGAAAACACA TCTTTACACA 
TTAATCTTGA ATCCAGACAA TAGTTTTGAA ATATTAGTTG ACCAGTCTGT TGTGAACAGT 
GGAAACCTGC TAAATGACAT GACCCCTCCG GTAAACCCTT CACGTGAAAT TGAGGACCCA 
GAAGACCGGA AGCCTGAAGA TTGGGATGAA AGGCCCAAAA TAGCAGATCC AGATGCTGTC 
AAGCCAGATG ACTGGGATGA AGATGCCCCT TCTAAGATTC CAGATGAAGA GGCCACAAAG 
CCTGAAGGCT GGTTAGATGA TGAACCCGAG TATATTCCAG ACCCTGATGC AGAGAAACCA 
GAAGATTGGG ATGAGGATAT GGACGGAGAA TGGGAGGCTC CTCAGATTGC CAACCCTAAG 
TGTGAGTCCG CCCCTGGGTG TGGTGTCTGG CAGCGACCTA TGATTGACAA CCCCAATTAT 
AAGGGCAAAT GGAAGCCTCC TATGATTGAC AATCCTAACT ACCAGGGAAT CTGGAAACCA 
AGGAAAATAC CAAATCCAGA TTTCTTTGAA GACCTGGAAC CTTTTAGGAT GACTCCTTTC 
AGCGCTATTG GTTTGGAGCT CTGGTCCATG ACATCCGACA TCTTTTTTGA CAACTTTATC 
ATTAGTGGTG ACCGAAGAGT AGTTGATGAC TGGGCCAATG ATGGGTGGGG CCTGAAGAAA 
GCTGCTGATG GGGCTGCAGA GCCAGGTGTA GTGGGGCAGA TGCTGGAGGC AGCTGAAGAG 
CGTCCATGGC TTTGGGTGGT CTACATTCTG ACTGTAGCGT TGCCAGTGTT CCTTGTGATC 
CTCTTCTGCT GTTCTGGAAA GAAACAGTCC AATGCTATGG AGTACAAGAA GACAGATGCT 
CCCCAGCCAG ATGTGAAGGA CGAAGAAGGG AAGGAAGAAG AGAAGAACAA GGGAGATGAA 
GAGGAAGAAG AGGAGAAGCT TGAAGAGAAA CAGAAGAGTG ATGCTGAAGA AGATGGTGGC 
ACTGGCAGTC AAGATGAGGA AGATAGCAAG CCTAAAGCAG AGGAGGATGA AATTTTGAAC 
AGATCACCAA GAAACAGAAA GCCACGAAGA GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Canx ( XM_008767680.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765902.1 Rattus norvegicus calnexin (Canx), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa33031
Clone ID Related Accession (Same CDS sequence)	XM_008767680.2 , XM_008767679.2
Accession Version	XM_008767680.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	calnexin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767680.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGGGA AGTGGTTACT GTGTTTGCTA CTGGTCCTTG GAACTGCAGC TATTCAGGCT 
CATGATGGAC ATGATGATGA CATGATTGAT ATTGAAGATG ATCTTGATGA TGTTATCGAA 
GAGGTAGAAG ATTCAAAATC TAAATCAGAT ACCAGCACTC CTCCATCTCC AAAGGTCACC 
TACAAAGCTC CAGTTCCAAC AGGGGAGGTT TATTTTGCTG ACTCCTTTGA CAGAGGGTCT 
CTGTCAGGGT GGATTTTATC TAAAGCCAAA AAAGACGACA CTGATGATGA AATTGCCAAA 
TATGACGGAA AGTGGGAGGT AGATGAAATG AAGGAAACAA AGCTTCCAGG TGATAAAGGA 
CTTGTATTGA TGTCTCGGGC CAAGCATCAT GCCATCTCTG CTAAACTGAA CAAGCCCTTC 
CTGTTTGATA CCAAGCCTCT CATTGTTCAG TATGAGGTTA ACTTTCAGAA TGGAATAGAA 
TGCGGTGGTG CCTACGTGAA GCTGCTATCC AAGACCTCAG AACTCAACCT GGATCAATTC 
CACGACAAGA CTCCGTATAC TATTATGTTT GGTCCAGATA AATGTGGAGA GGACTACAAA 
CTGCATTTCA TCTTTCGCCA CAAAAACCCC AAGACAGGTG TATATGAAGA AAAACATGCT 
AAGAGGCCAG ATGCAGATCT GAAGACCTAT TTCACTGACA AGAAAACACA TCTTTACACA 
TTAATCTTGA ATCCAGACAA TAGTTTTGAA ATATTAGTTG ACCAGTCTGT TGTGAACAGT 
GGAAACCTGC TAAATGACAT GACCCCTCCG GTAAACCCTT CACGTGAAAT TGAGGACCCA 
GAAGACCGGA AGCCTGAAGA TTGGGATGAA AGGCCCAAAA TAGCAGATCC AGATGCTGTC 
AAGCCAGATG ACTGGGATGA AGATGCCCCT TCTAAGATTC CAGATGAAGA GGCCACAAAG 
CCTGAAGGCT GGTTAGATGA TGAACCCGAG TATATTCCAG ACCCTGATGC AGAGAAACCA 
GAAGATTGGG ATGAGGATAT GGACGGAGAA TGGGAGGCTC CTCAGATTGC CAACCCTAAG 
TGTGAGTCCG CCCCTGGGTG TGGTGTCTGG CAGCGACCTA TGATTGACAA CCCCAATTAT 
AAGGGCAAAT GGAAGCCTCC TATGATTGAC AATCCTAACT ACCAGGGAAT CTGGAAACCA 
AGGAAAATAC CCAATCCAGA TTTCTTTGAA GACCTGGAAC CTTTTAGGAT GACTCCTTTC 
AGCGCTATTG GTTTGGAGCT CTGGTCCATG ACATCCGACA TCTTTTTTGA CAACTTTATC 
ATTAGTGGTG ACCGAAGAGT AGTTGATGAC TGGGCCAATG ATGGGTGGGG CCTGAAGAAA 
GCTGCTGATG GGGCTGCAGA GCCAGGTGTA GTGGGGCAGA TGCTGGAGGC AGCTGAAGAG 
CGTCCATGGC TTTGGGTGGT CTACATTCTG ACTGTAGCGT TGCCAGTGTT CCTTGTGATC 
CTCTTCTGCT GTTCTGGAAA GAAACAGTCC AATGCTATGG AGTACAAGAA GACAGATGCT 
CCCCAGCCAG ATGTGAAGGA CGAAGAAGGG AAGGAAGAAG AGAAGAACAA GGGAGATGAA 
GAGGAAGAAG AGGAGAAGCT TGAAGAGAAA CAGAAGAGTG ATGCTGAAGA AGATGGTGGC 
ACTGGCAGTC AAGATGAGGA AGATAGCAAG CCTAAAGCAG AGGAGGATGA AATTTTGAAC 
AGATCACCAA GAAACAGAAA GCCACGAAGA GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765902.1
CDS	146..1921
Translation	MEGKWLLCLLLVLGTAAIQAHDGHDDDMIDIEDDLDDVIEEVEDSKSKSDTSTPPSPKVTYKAPVPTGEVYFADSFDRGSLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTSELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATKPEGWLDDEPEYIPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIISGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMLEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQSNAMEYKKTDAPQPDVKDEEGKEEEKNKGDEEEEEEKLEEKQKSDAEEDGGTGSQDEEDSKPKAEEDEILNRSPRNRKPRRE

Target ORF information:

RefSeq Version	XM_008767680.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calnexin (Canx), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767680.2

ORF Insert Sequence:

ATGGAAGGGA AGTGGTTACT GTGTTTGCTA CTGGTCCTTG GAACTGCAGC TATTCAGGCT 
CATGATGGAC ATGATGATGA CATGATTGAT ATTGAAGATG ATCTTGATGA TGTTATCGAA 
GAGGTAGAAG ATTCAAAATC TAAATCAGAT ACCAGCACTC CTCCATCTCC AAAGGTCACC 
TACAAAGCTC CAGTTCCAAC AGGGGAGGTT TATTTTGCTG ACTCCTTTGA CAGAGGGTCT 
CTGTCAGGGT GGATTTTATC TAAAGCCAAA AAAGACGACA CTGATGATGA AATTGCCAAA 
TATGACGGAA AGTGGGAGGT AGATGAAATG AAGGAAACAA AGCTTCCAGG TGATAAAGGA 
CTTGTATTGA TGTCTCGGGC CAAGCATCAT GCCATCTCTG CTAAACTGAA CAAGCCCTTC 
CTGTTTGATA CCAAGCCTCT CATTGTTCAG TATGAGGTTA ACTTTCAGAA TGGAATAGAA 
TGCGGTGGTG CCTACGTGAA GCTGCTATCC AAGACCTCAG AACTCAACCT GGATCAATTC 
CACGACAAGA CTCCGTATAC TATTATGTTT GGTCCAGATA AATGTGGAGA GGACTACAAA 
CTGCATTTCA TCTTTCGCCA CAAAAACCCC AAGACAGGTG TATATGAAGA AAAACATGCT 
AAGAGGCCAG ATGCAGATCT GAAGACCTAT TTCACTGACA AGAAAACACA TCTTTACACA 
TTAATCTTGA ATCCAGACAA TAGTTTTGAA ATATTAGTTG ACCAGTCTGT TGTGAACAGT 
GGAAACCTGC TAAATGACAT GACCCCTCCG GTAAACCCTT CACGTGAAAT TGAGGACCCA 
GAAGACCGGA AGCCTGAAGA TTGGGATGAA AGGCCCAAAA TAGCAGATCC AGATGCTGTC 
AAGCCAGATG ACTGGGATGA AGATGCCCCT TCTAAGATTC CAGATGAAGA GGCCACAAAG 
CCTGAAGGCT GGTTAGATGA TGAACCCGAG TATATTCCAG ACCCTGATGC AGAGAAACCA 
GAAGATTGGG ATGAGGATAT GGACGGAGAA TGGGAGGCTC CTCAGATTGC CAACCCTAAG 
TGTGAGTCCG CCCCTGGGTG TGGTGTCTGG CAGCGACCTA TGATTGACAA CCCCAATTAT 
AAGGGCAAAT GGAAGCCTCC TATGATTGAC AATCCTAACT ACCAGGGAAT CTGGAAACCA 
AGGAAAATAC CCAATCCAGA TTTCTTTGAA GACCTGGAAC CTTTTAGGAT GACTCCTTTC 
AGCGCTATTG GTTTGGAGCT CTGGTCCATG ACATCCGACA TCTTTTTTGA CAACTTTATC 
ATTAGTGGTG ACCGAAGAGT AGTTGATGAC TGGGCCAATG ATGGGTGGGG CCTGAAGAAA 
GCTGCTGATG GGGCTGCAGA GCCAGGTGTA GTGGGGCAGA TGCTGGAGGC AGCTGAAGAG 
CGTCCATGGC TTTGGGTGGT CTACATTCTG ACTGTAGCGT TGCCAGTGTT CCTTGTGATC 
CTCTTCTGCT GTTCTGGAAA GAAACAGTCC AATGCTATGG AGTACAAGAA GACAGATGCT 
CCCCAGCCAG ATGTGAAGGA CGAAGAAGGG AAGGAAGAAG AGAAGAACAA GGGAGATGAA 
GAGGAAGAAG AGGAGAAGCT TGAAGAGAAA CAGAAGAGTG ATGCTGAAGA AGATGGTGGC 
ACTGGCAGTC AAGATGAGGA AGATAGCAAG CCTAAAGCAG AGGAGGATGA AATTTTGAAC 
AGATCACCAA GAAACAGAAA GCCACGAAGA GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Canx ( XM_008767679.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765901.1 Rattus norvegicus calnexin (Canx), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa33031
Clone ID Related Accession (Same CDS sequence)	XM_008767680.2 , XM_008767679.2
Accession Version	XM_008767679.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	calnexin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767679.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGGGA AGTGGTTACT GTGTTTGCTA CTGGTCCTTG GAACTGCAGC TATTCAGGCT 
CATGATGGAC ATGATGATGA CATGATTGAT ATTGAAGATG ATCTTGATGA TGTTATCGAA 
GAGGTAGAAG ATTCAAAATC TAAATCAGAT ACCAGCACTC CTCCATCTCC AAAGGTCACC 
TACAAAGCTC CAGTTCCAAC AGGGGAGGTT TATTTTGCTG ACTCCTTTGA CAGAGGGTCT 
CTGTCAGGGT GGATTTTATC TAAAGCCAAA AAAGACGACA CTGATGATGA AATTGCCAAA 
TATGACGGAA AGTGGGAGGT AGATGAAATG AAGGAAACAA AGCTTCCAGG TGATAAAGGA 
CTTGTATTGA TGTCTCGGGC CAAGCATCAT GCCATCTCTG CTAAACTGAA CAAGCCCTTC 
CTGTTTGATA CCAAGCCTCT CATTGTTCAG TATGAGGTTA ACTTTCAGAA TGGAATAGAA 
TGCGGTGGTG CCTACGTGAA GCTGCTATCC AAGACCTCAG AACTCAACCT GGATCAATTC 
CACGACAAGA CTCCGTATAC TATTATGTTT GGTCCAGATA AATGTGGAGA GGACTACAAA 
CTGCATTTCA TCTTTCGCCA CAAAAACCCC AAGACAGGTG TATATGAAGA AAAACATGCT 
AAGAGGCCAG ATGCAGATCT GAAGACCTAT TTCACTGACA AGAAAACACA TCTTTACACA 
TTAATCTTGA ATCCAGACAA TAGTTTTGAA ATATTAGTTG ACCAGTCTGT TGTGAACAGT 
GGAAACCTGC TAAATGACAT GACCCCTCCG GTAAACCCTT CACGTGAAAT TGAGGACCCA 
GAAGACCGGA AGCCTGAAGA TTGGGATGAA AGGCCCAAAA TAGCAGATCC AGATGCTGTC 
AAGCCAGATG ACTGGGATGA AGATGCCCCT TCTAAGATTC CAGATGAAGA GGCCACAAAG 
CCTGAAGGCT GGTTAGATGA TGAACCCGAG TATATTCCAG ACCCTGATGC AGAGAAACCA 
GAAGATTGGG ATGAGGATAT GGACGGAGAA TGGGAGGCTC CTCAGATTGC CAACCCTAAG 
TGTGAGTCCG CCCCTGGGTG TGGTGTCTGG CAGCGACCTA TGATTGACAA CCCCAATTAT 
AAGGGCAAAT GGAAGCCTCC TATGATTGAC AATCCTAACT ACCAGGGAAT CTGGAAACCA 
AGGAAAATAC CCAATCCAGA TTTCTTTGAA GACCTGGAAC CTTTTAGGAT GACTCCTTTC 
AGCGCTATTG GTTTGGAGCT CTGGTCCATG ACATCCGACA TCTTTTTTGA CAACTTTATC 
ATTAGTGGTG ACCGAAGAGT AGTTGATGAC TGGGCCAATG ATGGGTGGGG CCTGAAGAAA 
GCTGCTGATG GGGCTGCAGA GCCAGGTGTA GTGGGGCAGA TGCTGGAGGC AGCTGAAGAG 
CGTCCATGGC TTTGGGTGGT CTACATTCTG ACTGTAGCGT TGCCAGTGTT CCTTGTGATC 
CTCTTCTGCT GTTCTGGAAA GAAACAGTCC AATGCTATGG AGTACAAGAA GACAGATGCT 
CCCCAGCCAG ATGTGAAGGA CGAAGAAGGG AAGGAAGAAG AGAAGAACAA GGGAGATGAA 
GAGGAAGAAG AGGAGAAGCT TGAAGAGAAA CAGAAGAGTG ATGCTGAAGA AGATGGTGGC 
ACTGGCAGTC AAGATGAGGA AGATAGCAAG CCTAAAGCAG AGGAGGATGA AATTTTGAAC 
AGATCACCAA GAAACAGAAA GCCACGAAGA GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765901.1
CDS	230..2005
Translation	MEGKWLLCLLLVLGTAAIQAHDGHDDDMIDIEDDLDDVIEEVEDSKSKSDTSTPPSPKVTYKAPVPTGEVYFADSFDRGSLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKETKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTSELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIADPDAVKPDDWDEDAPSKIPDEEATKPEGWLDDEPEYIPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIISGDRRVVDDWANDGWGLKKAADGAAEPGVVGQMLEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQSNAMEYKKTDAPQPDVKDEEGKEEEKNKGDEEEEEEKLEEKQKSDAEEDGGTGSQDEEDSKPKAEEDEILNRSPRNRKPRRE

Target ORF information:

RefSeq Version	XM_008767679.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus calnexin (Canx), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767679.2

ORF Insert Sequence:

ATGGAAGGGA AGTGGTTACT GTGTTTGCTA CTGGTCCTTG GAACTGCAGC TATTCAGGCT 
CATGATGGAC ATGATGATGA CATGATTGAT ATTGAAGATG ATCTTGATGA TGTTATCGAA 
GAGGTAGAAG ATTCAAAATC TAAATCAGAT ACCAGCACTC CTCCATCTCC AAAGGTCACC 
TACAAAGCTC CAGTTCCAAC AGGGGAGGTT TATTTTGCTG ACTCCTTTGA CAGAGGGTCT 
CTGTCAGGGT GGATTTTATC TAAAGCCAAA AAAGACGACA CTGATGATGA AATTGCCAAA 
TATGACGGAA AGTGGGAGGT AGATGAAATG AAGGAAACAA AGCTTCCAGG TGATAAAGGA 
CTTGTATTGA TGTCTCGGGC CAAGCATCAT GCCATCTCTG CTAAACTGAA CAAGCCCTTC 
CTGTTTGATA CCAAGCCTCT CATTGTTCAG TATGAGGTTA ACTTTCAGAA TGGAATAGAA 
TGCGGTGGTG CCTACGTGAA GCTGCTATCC AAGACCTCAG AACTCAACCT GGATCAATTC 
CACGACAAGA CTCCGTATAC TATTATGTTT GGTCCAGATA AATGTGGAGA GGACTACAAA 
CTGCATTTCA TCTTTCGCCA CAAAAACCCC AAGACAGGTG TATATGAAGA AAAACATGCT 
AAGAGGCCAG ATGCAGATCT GAAGACCTAT TTCACTGACA AGAAAACACA TCTTTACACA 
TTAATCTTGA ATCCAGACAA TAGTTTTGAA ATATTAGTTG ACCAGTCTGT TGTGAACAGT 
GGAAACCTGC TAAATGACAT GACCCCTCCG GTAAACCCTT CACGTGAAAT TGAGGACCCA 
GAAGACCGGA AGCCTGAAGA TTGGGATGAA AGGCCCAAAA TAGCAGATCC AGATGCTGTC 
AAGCCAGATG ACTGGGATGA AGATGCCCCT TCTAAGATTC CAGATGAAGA GGCCACAAAG 
CCTGAAGGCT GGTTAGATGA TGAACCCGAG TATATTCCAG ACCCTGATGC AGAGAAACCA 
GAAGATTGGG ATGAGGATAT GGACGGAGAA TGGGAGGCTC CTCAGATTGC CAACCCTAAG 
TGTGAGTCCG CCCCTGGGTG TGGTGTCTGG CAGCGACCTA TGATTGACAA CCCCAATTAT 
AAGGGCAAAT GGAAGCCTCC TATGATTGAC AATCCTAACT ACCAGGGAAT CTGGAAACCA 
AGGAAAATAC CCAATCCAGA TTTCTTTGAA GACCTGGAAC CTTTTAGGAT GACTCCTTTC 
AGCGCTATTG GTTTGGAGCT CTGGTCCATG ACATCCGACA TCTTTTTTGA CAACTTTATC 
ATTAGTGGTG ACCGAAGAGT AGTTGATGAC TGGGCCAATG ATGGGTGGGG CCTGAAGAAA 
GCTGCTGATG GGGCTGCAGA GCCAGGTGTA GTGGGGCAGA TGCTGGAGGC AGCTGAAGAG 
CGTCCATGGC TTTGGGTGGT CTACATTCTG ACTGTAGCGT TGCCAGTGTT CCTTGTGATC 
CTCTTCTGCT GTTCTGGAAA GAAACAGTCC AATGCTATGG AGTACAAGAA GACAGATGCT 
CCCCAGCCAG ATGTGAAGGA CGAAGAAGGG AAGGAAGAAG AGAAGAACAA GGGAGATGAA 
GAGGAAGAAG AGGAGAAGCT TGAAGAGAAA CAGAAGAGTG ATGCTGAAGA AGATGGTGGC 
ACTGGCAGTC AAGATGAGGA AGATAGCAAG CCTAAAGCAG AGGAGGATGA AATTTTGAAC 
AGATCACCAA GAAACAGAAA GCCACGAAGA GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Cacna1h mutation in the GAERS model of absence epilepsy enhances T-type Ca
Scientific reports7(1)11513(2017 Sep)
Proft J,Rzhepetskyy Y,Lazniewska J,Zhang FX,Cain SM,Snutch TP,Zamponi GW,Weiss N

Stratified analysis of lectin-like chaperones in the folding disease-related metabolic syndrome rat model.
Biochemical and biophysical research communications478(1)247-253(2016 09)
Hirano M,Imagawa A,Totani K

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.
The Journal of biological chemistry291(3)1221-34(2016 Jan)
Urresti J,Ruiz-Meana M,Coccia E,Ar?valo JC,Castellano J,Fern?ndez-Sanz C,Galenkamp KM,Planells-Ferrer L,Moubarak RS,Llecha-Cano N,Reix S,Garc?a-Dorado D,Barneda-Zahonero B,Comella JX

Transmembrane and coiled-coil domain family 1 is a novel protein of the endoplasmic reticulum.
PloS one9(1)e85206(2014)
Zhang C,Kho YS,Wang Z,Chiang YT,Ng GK,Shaw PC,Wang Y,Qi RZ

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Canx cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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