Snx27 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snx27
Entrez Gene ID	260323
Full Name	sorting nexin family member 27
Synonyms	Mrt1
General protein information	Preferred Names sorting nexin family member 27 Names sorting nexin-27 MAP-responsive gene protein PDZ-protein Mrt1 methamphetamine (MAP) responsive transcript 1 methamphetamine-responsive transcript 1 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	may play a role in neuronal adaptation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_152847.2	NP_690060.2	sorting nexin-27 isoform b
NM_001110151.1	NP_001103621.1	sorting nexin-27 isoform a

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	snx27b	NP_956834.1
Canis lupus familiaris (dog)	SNX27	XP_005630870.1
Caenorhabditis elegans (roundworm)	snx-27	NP_492758.1
	SNX27	XP_001108415.2
Rattus norvegicus (Norway rat)	Snx27	NP_001103621.1
Gallus gallus (chicken)	SNX27	NP_001026517.1
Danio rerio (zebrafish)	snx27a	NP_001038565.1
Homo sapiens (human)	SNX27	NP_112180.4
Drosophila melanogaster (fruit fly)	CG32758	NP_727023.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001110	XP_003435749.1
Pan troglodytes (chimpanzee)	SNX27	XP_003949594.1
Bos taurus (cattle)	SNX27	NP_001092426.1
Mus musculus (house mouse)	Snx27	NP_001075953.1

Gene Ontology
Bibliography

Related articles in PubMed

VPS26A-SNX27 Interaction-Dependent mGluR5 Recycling in Dorsal Horn Neurons Mediates Neuropathic Pain in Rats.
Lin TB, Lai CY, Hsieh MC, Wang HH, Cheng JK, Chau YP, Chen GD, Peng HY
The Journal of neuroscience : the official journal of the Society for Neuroscience35(44)14943-55(2015 Nov)

Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3.
Singh V, Yang J, Cha B, Chen TE, Sarker R, Yin J, Avula LR, Tse M, Donowitz M
Molecular biology of the cell26(11)2030-43(2015 Jun)

Retromer and sorting nexins in endosomal sorting.
Gallon M, Cullen PJ
Biochemical Society transactions43(1)33-47(2015 Feb)

A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Gallon M, Clairfeuille T, Steinberg F, Mas C, Ghai R, Sessions RB, Teasdale RD, Collins BM, Cullen PJ
Proceedings of the National Academy of Sciences of the United States of America111(35)E3604-13(2014 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The regulation of the VPS26A-SNX27 interaction modifies mGluR5 trafficking which mediates neuropathic pain.
Title: VPS26A-SNX27 Interaction-Dependent mGluR5 Recycling in Dorsal Horn Neurons Mediates Neuropathic Pain in Rats.

SNX27 is required for the exocytosis of NHE3 from early endosome to plasma membrane and the regulation of the retention of NHE3 on the plasma membrane.
Title: Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3.

SNX27 is synaptically enriched and its level of expression regulates targeting of AMPARs to the neuronal surface. Loss of SNX27 abolishes recruitment of surface AMPARs during chemical LTP.
Title: Sorting Nexin 27 regulates basal and activity-dependent trafficking of AMPARs.

The surface expression of neuronal GIRK channels is regulated by the psychostimulant-sensitive sorting nexin 27 (SNX27) protein through a class I PDZ-binding interaction.
Title: Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27.

SNX27 promotes the endosomal movement of Kir3 (GIRK) channels, leading to reduced surface expression, increased degradation and smaller Kir3 potassium currents.
Title: A unique sorting nexin regulates trafficking of potassium channels via a PDZ domain interaction.

The following Snx27 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snx27 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00773	NM_001110151.1 Latest version!	Rattus norvegicus sorting nexin 27 (Snx27), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$314.30 $449.00
ORa02919	NM_152847.2 Latest version!	Rattus norvegicus sorting nexin 27 (Snx27), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snx27 ( NM_001110151.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001103621.1 Rattus norvegicus sorting nexin 27 (Snx27), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa00773
Clone ID Related Accession (Same CDS sequence)	NM_001110151.1
Accession Version	NM_001110151.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Rattus norvegicus(Norway rat)
Product	sorting nexin-27 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB051816.1, BF524912.1 and AC133978.2. Transcript Variant: This variant (1) encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB010245.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACG AGGACGGGGA AGGGATTCAC CCCTCAGCCC CGCACCGGAA TGGAGGCGGC 
GGCGGGGGGT CTGGGCTCCA CTGCGCCGGG AACGGTGGCG GGGGAGGCGG CGGCCCGCGG 
GTCGTGCGCA TTGTCAAGTC CGAATCCGGC TACGGCTTCA ACGTGCGGGG CCAAGTGAGC 
GAGGGCGGGC AACTGCGGAG CATCAACGGG GAGCTGTACG CGCCGCTGCA GCATGTGAGC 
GCCGTGCTGC CCGGGGGGGC GGCCGACCGG GCCGGGGTGC GCAAGGGGGA CCGCATCCTG 
GAGGTGAACG GCGTGAATGT TGAGGGGGCG ACACACAAGC AGGTGGTGGA CCTGATCCGA 
GCAGGCGAGA AGGAATTGAT CTTGACAGTG TTGTCTGTAC CTCCTCATGA GGCTGATAAC 
CTAGACCCCA GTGACGACTC CTTGGGACAA TCATTTTATG ATTACACAGA AAAGCAAGCA 
GTGCCCATAT CGGTCCCCAC ATACAAACAT GTGGAGCAGA ATGGTGAGAA ATTTGTGGTA 
TACAATGTTT ATATGGCCGG GAGGCAGCTG TGTTCTAAGC GGTACCGGGA GTTTGCCATT 
CTGCACCAAA ACCTGAAGAG AGAGTTTGCC AACTTTACAT TTCCTCGACT TCCAGGAAAG 
TGGCCATTCT CATTATCAGA GCAACAGTTA GATGCCCGGC GTCGGGGGTT GGAAGAATAT 
CTAGAAAAGG TGTGCTCCAT CCGAGTCATT GGTGAGAGCG ACATCATGCA GGAGTTCCTG 
TCAGAATCTG ATGAGAATTA CAATGGTGTG TCTGATGTGG AGCTGAGAGT AGCATTACCA 
GATGGAGCAA CTGTTACTGT CAGAGTTAAA AAGAACAGCA CCACAGACCA AGTGTACCAG 
GCTATTGCAG CAAAGGTTGG CATGGACAGT ACAACAGTGA ACTACTTTGC CTTATTTGAA 
GTCATCAATC ATTCCTTTGT ACGTAAGCTG GCCCCTAATG AATTTCCTCA TAAACTGTAC 
GTCCAGAATT ACACATCAGC TGTGCCAGGC ACCTGCCTGA CCATTCGCAA GTGGCTCTTT 
ACCACAGAAG AAGAAGTCCT CTTAAATGAC AATGACCTTG CTGTCACGTA CTTCTTTCAT 
CAGGCTGTTG ATGATGTAAA GAAAGGTTAC ATTAAAGCGG AGGAGAAGTC TTACCAGTTA 
CAGAAGCTGT ATGAACAAAG GAAGATGGTC ATGTACCTCA ACATGCTAAG GACCTGTGAG 
GGCTACAATG AAATCATCTT CCCTCACTGT GCCTGCGACT CCAGGAGGAA GGGGCATGTT 
ATCACAGCCA TCAGCATCAC GCACTTTAAA CTTCATGCCT GCACTGAAGA AGGGCAGCTG 
GAGAACCAGG TAATAGCGTT TGAATGGGAT GAGATGCAGC GATGGGACAC AGACGAAGAA 
GGAATGGCCT TCTGTTTTGA ATATGCACGA GGAGAGAAGA AGCCTCGATG GGTTAAAATC 
TTCACACCAT ATTTCAATTA CATGCATGAG TGCTTTGAGA GGGTGTTCTG CGAGCTCAAG 
TGGAGAAAAG AGAATATTTT CCAGATGGCG AGGTCACAAC AGAGGGATGT GGCCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001103621.1
CDS	121..1740
Translation	MADEDGEGIHPSAPHRNGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDGATVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEVLLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKENIFQMARSQQRDVAT

Target ORF information:

RefSeq Version	NM_001110151.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sorting nexin 27 (Snx27), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001110151.1

ORF Insert Sequence:

ATGGCGGACG AGGACGGGGA AGGGATTCAC CCCTCAGCCC CGCACCGGAA TGGAGGCGGC 
GGCGGGGGGT CTGGGCTCCA CTGCGCCGGG AACGGTGGCG GGGGAGGCGG CGGCCCGCGG 
GTCGTGCGCA TTGTCAAGTC CGAATCCGGC TACGGCTTCA ACGTGCGGGG CCAAGTGAGC 
GAGGGCGGGC AACTGCGGAG CATCAACGGG GAGCTGTACG CGCCGCTGCA GCATGTGAGC 
GCCGTGCTGC CCGGGGGGGC GGCCGACCGG GCCGGGGTGC GCAAGGGGGA CCGCATCCTG 
GAGGTGAACG GCGTGAATGT TGAGGGGGCG ACACACAAGC AGGTGGTGGA CCTGATCCGA 
GCAGGCGAGA AGGAATTGAT CTTGACAGTG TTGTCTGTAC CTCCTCATGA GGCTGATAAC 
CTAGACCCCA GTGACGACTC CTTGGGACAA TCATTTTATG ATTACACAGA AAAGCAAGCA 
GTGCCCATAT CGGTCCCCAC ATACAAACAT GTGGAGCAGA ATGGTGAGAA ATTTGTGGTA 
TACAATGTTT ATATGGCCGG GAGGCAGCTG TGTTCTAAGC GGTACCGGGA GTTTGCCATT 
CTGCACCAAA ACCTGAAGAG AGAGTTTGCC AACTTTACAT TTCCTCGACT TCCAGGAAAG 
TGGCCATTCT CATTATCAGA GCAACAGTTA GATGCCCGGC GTCGGGGGTT GGAAGAATAT 
CTAGAAAAGG TGTGCTCCAT CCGAGTCATT GGTGAGAGCG ACATCATGCA GGAGTTCCTG 
TCAGAATCTG ATGAGAATTA CAATGGTGTG TCTGATGTGG AGCTGAGAGT AGCATTACCA 
GATGGAGCAA CTGTTACTGT CAGAGTTAAA AAGAACAGCA CCACAGACCA AGTGTACCAG 
GCTATTGCAG CAAAGGTTGG CATGGACAGT ACAACAGTGA ACTACTTTGC CTTATTTGAA 
GTCATCAATC ATTCCTTTGT ACGTAAGCTG GCCCCTAATG AATTTCCTCA TAAACTGTAC 
GTCCAGAATT ACACATCAGC TGTGCCAGGC ACCTGCCTGA CCATTCGCAA GTGGCTCTTT 
ACCACAGAAG AAGAAGTCCT CTTAAATGAC AATGACCTTG CTGTCACGTA CTTCTTTCAT 
CAGGCTGTTG ATGATGTAAA GAAAGGTTAC ATTAAAGCGG AGGAGAAGTC TTACCAGTTA 
CAGAAGCTGT ATGAACAAAG GAAGATGGTC ATGTACCTCA ACATGCTAAG GACCTGTGAG 
GGCTACAATG AAATCATCTT CCCTCACTGT GCCTGCGACT CCAGGAGGAA GGGGCATGTT 
ATCACAGCCA TCAGCATCAC GCACTTTAAA CTTCATGCCT GCACTGAAGA AGGGCAGCTG 
GAGAACCAGG TAATAGCGTT TGAATGGGAT GAGATGCAGC GATGGGACAC AGACGAAGAA 
GGAATGGCCT TCTGTTTTGA ATATGCACGA GGAGAGAAGA AGCCTCGATG GGTTAAAATC 
TTCACACCAT ATTTCAATTA CATGCATGAG TGCTTTGAGA GGGTGTTCTG CGAGCTCAAG 
TGGAGAAAAG AGAATATTTT CCAGATGGCG AGGTCACAAC AGAGGGATGT GGCCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Snx27 ( NM_152847.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_690060.2 Rattus norvegicus sorting nexin 27 (Snx27), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa02919
Clone ID Related Accession (Same CDS sequence)	NM_152847.2
Accession Version	NM_152847.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Rattus norvegicus(Norway rat)
Product	sorting nexin-27 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB051816.1, BF524912.1 and AC133978.2. On Oct 26, 2007 this sequence version replaced NM_152847.1. Transcript Variant: This variant (2) uses an alternate splice junction at the 5' end of a coding exon compared to variant 1. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB051816.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACG AGGACGGGGA AGGGATTCAC CCCTCAGCCC CGCACCGGAA TGGAGGCGGC 
GGCGGGGGGT CTGGGCTCCA CTGCGCCGGG AACGGTGGCG GGGGAGGCGG CGGCCCGCGG 
GTCGTGCGCA TTGTCAAGTC CGAATCCGGC TACGGCTTCA ACGTGCGGGG CCAAGTGAGC 
GAGGGCGGGC AACTGCGGAG CATCAACGGG GAGCTGTACG CGCCGCTGCA GCATGTGAGC 
GCCGTGCTGC CCGGGGGGGC GGCCGACCGG GCCGGGGTGC GCAAGGGGGA CCGCATCCTG 
GAGGTGAACG GCGTGAATGT TGAGGGGGCG ACACACAAGC AGGTGGTGGA CCTGATCCGA 
GCAGGCGAGA AGGAATTGAT CTTGACAGTG TTGTCTGTAC CTCCTCATGA GGCTGATAAC 
CTAGACCCCA GTGACGACTC CTTGGGACAA TCATTTTATG ATTACACAGA AAAGCAAGCA 
GTGCCCATAT CGGTCCCCAC ATACAAACAT GTGGAGCAGA ATGGTGAGAA ATTTGTGGTA 
TACAATGTTT ATATGGCCGG GAGGCAGCTG TGTTCTAAGC GGTACCGGGA GTTTGCCATT 
CTGCACCAAA ACCTGAAGAG AGAGTTTGCC AACTTTACAT TTCCTCGACT TCCAGGAAAG 
TGGCCATTCT CATTATCAGA GCAACAGTTA GATGCCCGGC GTCGGGGGTT GGAAGAATAT 
CTAGAAAAGG TGTGCTCCAT CCGAGTCATT GGTGAGAGCG ACATCATGCA GGAGTTCCTG 
TCAGAATCTG ATGAGAATTA CAATGGTGTG TCTGATGTGG AGCTGAGAGT AGCATTACCA 
GATGGAGCAA CTGTTACTGT CAGAGTTAAA AAGAACAGCA CCACAGACCA AGTGTACCAG 
GCTATTGCAG CAAAGGTTGG CATGGACAGT ACAACAGTGA ACTACTTTGC CTTATTTGAA 
GTCATCAATC ATTCCTTTGT ACGTAAGCTG GCCCCTAATG AATTTCCTCA TAAACTGTAC 
GTCCAGAATT ACACATCAGC TGTGCCAGGC ACCTGCCTGA CCATTCGCAA GTGGCTCTTT 
ACCACAGAAG AAGAAGTCCT CTTAAATGAC AATGACCTTG CTGTCACGTA CTTCTTTCAT 
CAGGCTGTTG ATGATGTAAA GAAAGGTTAC ATTAAAGCGG AGGAGAAGTC TTACCAGTTA 
CAGAAGCTGT ATGAACAAAG GAAGATGGTC ATGTACCTCA ACATGCTAAG GACCTGTGAG 
GGCTACAATG AAATCATCTT CCCTCACTGT GCCTGCGACT CCAGGAGGAA GGGGCATGTT 
ATCACAGCCA TCAGCATCAC GCACTTTAAA CTTCATGCCT GCACTGAAGA AGGGCAGCTG 
GAGAACCAGG TAATAGCGTT TGAATGGGAT GAGATGCAGC GATGGGACAC AGACGAAGAA 
GGAATGGCCT TCTGTTTTGA ATATGCACGA GGAGAGAAGA AGCCTCGATG GGTTAAAATC 
TTCACACCAT ATTTCAATTA CATGCATGAG TGCTTTGAGA GGGTGTTCTG CGAGCTCAAG 
TGGAGAAAAG AGGAATATTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690060.2
CDS	121..1701
Translation	MADEDGEGIHPSAPHRNGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDGATVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEVLLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKEEY

Target ORF information:

RefSeq Version	NM_152847.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sorting nexin 27 (Snx27), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152847.2

ORF Insert Sequence:

ATGGCGGACG AGGACGGGGA AGGGATTCAC CCCTCAGCCC CGCACCGGAA TGGAGGCGGC 
GGCGGGGGGT CTGGGCTCCA CTGCGCCGGG AACGGTGGCG GGGGAGGCGG CGGCCCGCGG 
GTCGTGCGCA TTGTCAAGTC CGAATCCGGC TACGGCTTCA ACGTGCGGGG CCAAGTGAGC 
GAGGGCGGGC AACTGCGGAG CATCAACGGG GAGCTGTACG CGCCGCTGCA GCATGTGAGC 
GCCGTGCTGC CCGGGGGGGC GGCCGACCGG GCCGGGGTGC GCAAGGGGGA CCGCATCCTG 
GAGGTGAACG GCGTGAATGT TGAGGGGGCG ACACACAAGC AGGTGGTGGA CCTGATCCGA 
GCAGGCGAGA AGGAATTGAT CTTGACAGTG TTGTCTGTAC CTCCTCATGA GGCTGATAAC 
CTAGACCCCA GTGACGACTC CTTGGGACAA TCATTTTATG ATTACACAGA AAAGCAAGCA 
GTGCCCATAT CGGTCCCCAC ATACAAACAT GTGGAGCAGA ATGGTGAGAA ATTTGTGGTA 
TACAATGTTT ATATGGCCGG GAGGCAGCTG TGTTCTAAGC GGTACCGGGA GTTTGCCATT 
CTGCACCAAA ACCTGAAGAG AGAGTTTGCC AACTTTACAT TTCCTCGACT TCCAGGAAAG 
TGGCCATTCT CATTATCAGA GCAACAGTTA GATGCCCGGC GTCGGGGGTT GGAAGAATAT 
CTAGAAAAGG TGTGCTCCAT CCGAGTCATT GGTGAGAGCG ACATCATGCA GGAGTTCCTG 
TCAGAATCTG ATGAGAATTA CAATGGTGTG TCTGATGTGG AGCTGAGAGT AGCATTACCA 
GATGGAGCAA CTGTTACTGT CAGAGTTAAA AAGAACAGCA CCACAGACCA AGTGTACCAG 
GCTATTGCAG CAAAGGTTGG CATGGACAGT ACAACAGTGA ACTACTTTGC CTTATTTGAA 
GTCATCAATC ATTCCTTTGT ACGTAAGCTG GCCCCTAATG AATTTCCTCA TAAACTGTAC 
GTCCAGAATT ACACATCAGC TGTGCCAGGC ACCTGCCTGA CCATTCGCAA GTGGCTCTTT 
ACCACAGAAG AAGAAGTCCT CTTAAATGAC AATGACCTTG CTGTCACGTA CTTCTTTCAT 
CAGGCTGTTG ATGATGTAAA GAAAGGTTAC ATTAAAGCGG AGGAGAAGTC TTACCAGTTA 
CAGAAGCTGT ATGAACAAAG GAAGATGGTC ATGTACCTCA ACATGCTAAG GACCTGTGAG 
GGCTACAATG AAATCATCTT CCCTCACTGT GCCTGCGACT CCAGGAGGAA GGGGCATGTT 
ATCACAGCCA TCAGCATCAC GCACTTTAAA CTTCATGCCT GCACTGAAGA AGGGCAGCTG 
GAGAACCAGG TAATAGCGTT TGAATGGGAT GAGATGCAGC GATGGGACAC AGACGAAGAA 
GGAATGGCCT TCTGTTTTGA ATATGCACGA GGAGAGAAGA AGCCTCGATG GGTTAAAATC 
TTCACACCAT ATTTCAATTA CATGCATGAG TGCTTTGAGA GGGTGTTCTG CGAGCTCAAG 
TGGAGAAAAG AGGAATATTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

VPS26A-SNX27 Interaction-Dependent mGluR5 Recycling in Dorsal Horn Neurons Mediates Neuropathic Pain in Rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience35(44)14943-55(2015 Nov)
Lin TB,Lai CY,Hsieh MC,Wang HH,Cheng JK,Chau YP,Chen GD,Peng HY

Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3.
Molecular biology of the cell26(11)2030-43(2015 Jun)
Singh V,Yang J,Cha B,Chen TE,Sarker R,Yin J,Avula LR,Tse M,Donowitz M

Retromer and sorting nexins in endosomal sorting.
Biochemical Society transactions43(1)33-47(2015 Feb)
Gallon M,Cullen PJ

A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Proceedings of the National Academy of Sciences of the United States of America111(35)E3604-13(2014 Sep)
Gallon M,Clairfeuille T,Steinberg F,Mas C,Ghai R,Sessions RB,Teasdale RD,Collins BM,Cullen PJ

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Snx27 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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