Plcg1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Plcg1
Entrez Gene ID	25738
Full Name	phospholipase C, gamma 1
Synonyms	PPLCA
General protein information	Preferred Names phospholipase C, gamma 1 Names 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 PLC-148 PLC-II PLC-gamma-1 phosphoinositide phospholipase C phosphoinositide phospholipase C-gamma-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q42
Summary	mediates intracellular agonist-induced Ca2+ entry (ACE); serves as a guanine nucleotide exchange factor for the nuclear GTPase PIKE [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013187.1	NP_037319.1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Plcg1	NP_037319.1
Pan troglodytes (chimpanzee)	PLCG1	XP_514650.3
Bos taurus (cattle)	PLCG1	NP_776850.1
Drosophila melanogaster (fruit fly)	sl	NP_476726.2
Mus musculus (house mouse)	Plcg1	NP_067255.2
Homo sapiens (human)	PLCG1	NP_002651.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011152	XP_309496.4
Caenorhabditis elegans (roundworm)	plc-3	NP_496205.2
	PLCG1	XP_001087295.2
Canis lupus familiaris (dog)	PLCG1	XP_005635117.1
Gallus gallus (chicken)	PLCG1	XP_004947069.1
Danio rerio (zebrafish)	plcg1	NP_919388.1
Arabidopsis thaliana (thale cress)	PLC2	NP_187464.1
Arabidopsis thaliana (thale cress)	AT3G55940	NP_191153.1

Gene Ontology
Bibliography

Related articles in PubMed

Forebrain-specific ablation of phospholipase C?1 causes manic-like behavior.
Yang YR, Jung JH, Kim SJ, Hamada K, Suzuki A, Kim HJ, Lee JH, Kwon OB, Lee YK, Kim J, Kim EK, Jang HJ, Kang DS, Choi JS, Lee CJ, Marshall J, Koh HY, Kim CJ, Seok H, Kim SH, Choi JH, Choi YB, Cocco L, Ryu SH, Kim JH, Suh PG
Molecular psychiatry22(10)1473-1482(2017 Oct)

Phospholipase C?1 Mediates Intima Formation Through Akt-Notch1 Signaling Independent of the Phospholipase Activity.
Jiang D, Zhuang J, Peng W, Lu Y, Liu H, Zhao Q, Chi C, Li X, Zhu G, Xu X, Yan C, Xu Y, Ge J, Pang J
Journal of the American Heart Association6(7)(2017 Jul)

c-Jun enhances intestinal epithelial restitution after wounding by increasing phospholipase C-?1 transcription.
Wang PY, Wang SR, Xiao L, Chen J, Wang JY, Rao JN
American journal of physiology. Cell physiology312(4)C367-C375(2017 Apr)

MiR-30s Family Inhibit the Proliferation and Apoptosis in Human Coronary Artery Endothelial Cells Through Targeting the 3'UTR Region of ITGA4 and PLCG1.
Ma F, Li T, Zhang H, Wu G
Journal of cardiovascular pharmacology68(5)327-333(2016 Nov)

Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin ?1 and phosphorylation of downstream phospholipase C?1.
Gao G, He J, Nong L, Xie H, Huang Y, Xu N, Zhou D
Molecular medicine reports14(3)2457-64(2016 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings indicate that c-Jun induces PLCgamma1 expression transcriptionally and enhances rapid epithelial restitution after injury by activating Ca(2+) signal.
Title: c-Jun enhances intestinal epithelial restitution after wounding by increasing phospholipase C-?1 transcription.

periodic mechanical stress induced ECM expression and the migration of NP cells via upregulating the expression of integrin alpha1 and the phosphorylation of downstream PLCgamma1. These findings provide novel information to aid the understanding of the pathogenesis and development of IDD.
Title: Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin ?1 and phosphorylation of downstream phospholipase C?1.

FGFR1/2 act in concert to recruit and transphosphorylate phospholipase Cgamma1.
Title: Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase C?.

These results suggest that colitis-induced and brain-derived neurotrophic factor-mediated calcitonin generelated peptide expression in sensory activation is regulated by a unique pathway involving brain-derived neurotrophic factorphospholipase C gamma-cAMP-responsive element binding protein axis.
Title: EXPRESS: Phospholipase C gamma mediates endogenous brain-derived neurotrophic factor - regulated calcitonin gene-related peptide expression in colitis - induced visceral pain.

PDGF activates the GIT1PLCG1mediated ERK1/2 pathway to control chondrocyte proliferation.
Title: PDGF regulates chondrocyte proliferation through activation of the GIT1- and PLC?1-mediated ERK1/2 signaling pathway.

The following Plcg1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plcg1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa02265	NM_013187.1 Latest version!	Rattus norvegicus phospholipase C, gamma 1 (Plcg1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$951.30 $1359.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Plcg1 ( NM_013187.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037319.1 Rattus norvegicus phospholipase C, gamma 1 (Plcg1), mRNA.

Price & Availability↑

CloneID	ORa02265
Clone ID Related Accession (Same CDS sequence)	NM_013187.1
Accession Version	NM_013187.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3873bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J03806.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J03806.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGCG TCGGGACCCC CTGCGCCAAC GGCTGCGGGC CCAGCGCGCC CTCCGAAGCG 
GAGGTGCTGC ACCTCTGCCG CAGCCTCGAG GTGGGCACCG TCATGACTTT GTTCTACTCC 
AAGAAGTCGC AGCGGCCAGA ACGGAAGACC TTCCAGGTCA AGTTGGAGAC GCGCCAGATC 
ACATGGAGCC GCGGTGCGGA CAAAATCGAG GGGTCCATCG ATATCCGAGA AATCAAGGAG 
ATCCGCCCAG GGAAGACTTC CCGGGACTTT GACCGCTACC AAGAAGACCC TGCCTTCCGG 
CCAGATCAGT CACACTGTTT TGTCATCCTC TATGGAATGG AATTCCGCCT GAAGACCCTG 
AGCCTGCAAG CCACATCTGA GGATGAAGTG AACATGTGGA TCAAGGGCTT AACTTGGCTC 
ATGGAAGATA CGCTGCAGGC GGCCACACCC CTGCAAATTG AGAGATGGCT CCGGAAGCAG 
TTCTACTCAG TGGATCGTAA CCGAGAGGAT CGTATATCAG CCAAGGACCT GAAGAACATG 
CTGTCACAGG TCAACTACCG GGTCCCCAAC ATGCGCTTCC TCCGAGAGCG GCTGACGGAC 
TTTGAACAGC GCAGCGGGGA CATCACCTAT GGGCAGTTTG CTCAGCTTTA CCGCAGCCTC 
ATGTACAGCG CCCAGAAGAC GATGGACCTT CCGTTCTTGG AAACCAACAC TTTGAGGACT 
GGAGAGCGGC CAGAGCTTTG CCAGGTGTCC CTTTCTGAGT TCCAGCAGTT CCTTCTTGAG 
TACCAGGGGG AGCTGTGGGC TGTCGACCGG CTTCAGGTGC AGGAATTTAT GCTCAGCTTC 
CTTCGAGACC CCTTGCGAGA GATTGAGGAG CCATACTTCT TCTTGGATGA GCTTGTCACC 
TTTCTGTTCT CCAAAGAGAA CAGTGTGTGG AACTCACAGC TGGATGCCGT GTGCCCAGAA 
ACCATGAACA ACCCACTGTC TCACTATTGG ATCTCTTCCT CGCATAATAC GTATCTGACT 
GGGGACCAGT TCTCCAGCGA GTCCTCCCTG GAAGCCTACG CTCGCTGCCT GAGGATGGGC 
TGTCGCTGCA TCGAGTTGGA CTGCTGGGAT GGGCCAGATG GGATGCCAGT CATTTACCAT 
GGGCACACCC TCACCACCAA GATTAAGTTC TCAGATGTCC TGCACACCAT CAAGGAGCAC 
GCGTTCGTAG CCTCAGAGTA CCCTGTCATC CTGTCCATCG AGGACCACTG CAGCATTGCC 
CAGCAGAGGA ACATGGCCCA GCACTTCAGG AAGGTGCTCG GTGACACGCT CCTCACCAAG 
CCCGTGGACA TTGCCGCTGA TGGGCTCCCT TCTCCCAACC AGCTCAAGAG GAAGATCCTG 
ATTAAGCATA AGAAGCTGGC TGAGGGCAGT GCCTATGAGG AGGTGCCTAC CTCTGTGATG 
TACTCTGAGA ATGACATCAG TAACTCCATC AAGAATGGTA TCCTCTACTT GGAGGACCCC 
GTGAATCATG AGTGGTACCC CCACTACTTT GTTCTGACTA GCAGCAAGAT CTACTACTCT 
GAGGAGACCA GCAGTGACCA GGGAAATGAG GATGAAGAGG AGCCGAAGGA GGCCAGTGGC 
AGCACAGAGC TGCACTCGAG CGAGAAGTGG TTCCACGGGA AGCTCGGGGC TGGGCGCGAC 
GGGCGGCACA TTGCTGAGCG CCTGCTCACC GAGTACTGCA TAGAGACTGG GGCTCCCGAT 
GGCTCCTTCC TAGTGCGAGA AAGTGAGACC TTCGTGGGGG ACTACACGCT GTCTTTTTGG 
CGGAATGGGA AAGTCCAGCA CTGCCGTATC CACTCCCGGC AGGATGCTGG GACTCCTAAG 
TTCTTCTTGA CAGATAACCT TGTCTTTGAC TCTCTCTATG ACCTCATCAC ACATTATCAG 
CAAGTGCCCC TGCGCTGCAA TGAGTTTGAG ATGCGCCTTT CAGAGCCTGT TCCACAGACG 
AATGCCCATG AGAGCAAAGA GTGGTACCAC GCAAGCCTGA CTAGAGCTCA GGCTGAACAC 
ATGCTGATGC GAGTACCCCG TGATGGGGCC TTCCTGGTGC GGAAGCGCAA CGAGCCCAAC 
TCCTATGCCA TCTCTTTCCG GGCTGAGGGA AAGATCAAGC ACTGCCGAGT ACAGCAGGAA 
GGCCAGACTG TGATGCTGGG GAACTCTGAG TTTGACAGCC TGGTCGACCT CATCAGCTAC 
TATGAGAAGC ATCCCCTGTA CCGCAAAATG AAACTGCGCT ACCCCATCAA CGAGGAGGCG 
CTGGAGAAGA TTGGGACAGC TGAACCCGAT TATGGGGCAC TGTATGAGGG CCGCAACCCT 
GGTTTCTATG TGGAGGCCAA CCCTATGCCA ACTTTCAAGT GTGCAGTAAA AGCTCTCTTC 
GACTACAAGG CCCAGAGAGA GGATGAGCTG ACTTTTACCA AGAGCGCCAT CATCCAGAAT 
GTGGAAAAGC AAGATGGTGG CTGGTGGCGT GGGGACTATG GTGGGAAGAA GCAGCTGTGG 
TTCCCCTCAA ACTATGTGGA AGAGATGATC AATCCAGCAA TCCTAGAGCC GGAGAGGGAG 
CATCTGGATG AGAACAGCCC ACTGGGGGAC TTGCTGCGAG GGGTCTTAGA TGTGCCAGCC 
TGCCAGATCG CCATTCGTCC TGAGGGCAAA AACAACCGGC TCTTCGTCTT CTCCATCAGC 
ATGCCGTCAG TGGCTCAGTG GTCCCTAGAC GTTGCCGCTG ACTCACAGGA GGAGTTGCAG 
GACTGGGTGA AAAAGATCCG TGAAGTTGCC CAGACTGCAG ATGCCAGGCT TACTGAGGGG 
AAGATGATGG AGAGGAGGAA GAAGATCGCC TTGGAGCTCT CCGAGCTCGT GGTCTACTGC 
CGGCCTGTTC CCTTTGACGA AGAGAAGATT GGCACAGAAC GCGCTTGTTA CCGGGACATG 
TCCTCCTTTC CGGAAACCAA GGCTGAGAAG TATGTGAACA AGGCCAAAGG CAAGAAGTTC 
CTCCAGTACA ACCGGCTGCA GCTCTCTCGC ATCTACCCTA AGGGTCAGAG GCTGGACTCC 
TCCAATTATG ACCCTCTGCC CATGTGGATC TGTGGCAGCC AGCTTGTAGC TCTCAATTTT 
CAGACCCCAG ACAAGCCTAT GCAGATGAAC CAGGCCCTCT TCATGGCTGG TGGACACTGT 
GGCTATGTGC TGCAGCCAAG CACCATGAGA GATGAAGCCT TTGACCCCTT TGATAAGAGC 
AGTCTCCGAG GTCTGGAGCC CTGTGTCATT TGCATTGAGG TGCTGGGGGC CAGGCATCTG 
CCGAAGAATG GCCGGGGTAT TGTGTGTCCT TTCGTGGAGA TTGAAGTGGC TGGGGCAGAG 
TACGACAGCA CCAAGCAGAA GACAGAGTTT GTAGTGGACA ATGGACTGAA CCCTGTGTGG 
CCTGCAAAGC CCTTCCACTT CCAGATCAGT AACCCAGAGT TTGCCTTTCT GCGCTTTGTG 
GTGTATGAGG AAGACATGTT TAGTGACCAG AACTTCTTGG CTCAGGCTAC TTTCCCAGTA 
AAAGGCCTGA AGACAGGATA CAGAGCAGTG CCTTTGAAGA ACAACTACAG TGAAGACCTG 
GAGTTGGCCT CCCTGCTCAT CAAGATTGAC ATTTTCCCTG CTAAGGAGAA TGGTGACCTC 
AGCCCTTTCA GTGGTACATC CCTAAGGGAA CGGGCCTCAG ATGCCTCCAG CCAGCTGTTC 
CATGTCCGGG CCCGGGAAGG GTCCTTTGAA GCCAGATACC AGCAGCCATT TGAAGACTTC 
CGCATCTCGC AGGAGCATCT CGCAGACCAT TTTGACAGTC GGGAACGAAG GGCCCCAAGA 
AGGACTCGGG TCAATGGAGA CAACCGCCTC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037319.1
CDS	95..3967
Translation	MAGVGTPCANGCGPSAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDFEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNTLRTGERPELCQVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPETMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAILEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL

Target ORF information:

RefSeq Version	NM_013187.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phospholipase C, gamma 1 (Plcg1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013187.1

ORF Insert Sequence:

ATGGCGGGCG TCGGGACCCC CTGCGCCAAC GGCTGCGGGC CCAGCGCGCC CTCCGAAGCG 
GAGGTGCTGC ACCTCTGCCG CAGCCTCGAG GTGGGCACCG TCATGACTTT GTTCTACTCC 
AAGAAGTCGC AGCGGCCAGA ACGGAAGACC TTCCAGGTCA AGTTGGAGAC GCGCCAGATC 
ACATGGAGCC GCGGTGCGGA CAAAATCGAG GGGTCCATCG ATATCCGAGA AATCAAGGAG 
ATCCGCCCAG GGAAGACTTC CCGGGACTTT GACCGCTACC AAGAAGACCC TGCCTTCCGG 
CCAGATCAGT CACACTGTTT TGTCATCCTC TATGGAATGG AATTCCGCCT GAAGACCCTG 
AGCCTGCAAG CCACATCTGA GGATGAAGTG AACATGTGGA TCAAGGGCTT AACTTGGCTC 
ATGGAAGATA CGCTGCAGGC GGCCACACCC CTGCAAATTG AGAGATGGCT CCGGAAGCAG 
TTCTACTCAG TGGATCGTAA CCGAGAGGAT CGTATATCAG CCAAGGACCT GAAGAACATG 
CTGTCACAGG TCAACTACCG GGTCCCCAAC ATGCGCTTCC TCCGAGAGCG GCTGACGGAC 
TTTGAACAGC GCAGCGGGGA CATCACCTAT GGGCAGTTTG CTCAGCTTTA CCGCAGCCTC 
ATGTACAGCG CCCAGAAGAC GATGGACCTT CCGTTCTTGG AAACCAACAC TTTGAGGACT 
GGAGAGCGGC CAGAGCTTTG CCAGGTGTCC CTTTCTGAGT TCCAGCAGTT CCTTCTTGAG 
TACCAGGGGG AGCTGTGGGC TGTCGACCGG CTTCAGGTGC AGGAATTTAT GCTCAGCTTC 
CTTCGAGACC CCTTGCGAGA GATTGAGGAG CCATACTTCT TCTTGGATGA GCTTGTCACC 
TTTCTGTTCT CCAAAGAGAA CAGTGTGTGG AACTCACAGC TGGATGCCGT GTGCCCAGAA 
ACCATGAACA ACCCACTGTC TCACTATTGG ATCTCTTCCT CGCATAATAC GTATCTGACT 
GGGGACCAGT TCTCCAGCGA GTCCTCCCTG GAAGCCTACG CTCGCTGCCT GAGGATGGGC 
TGTCGCTGCA TCGAGTTGGA CTGCTGGGAT GGGCCAGATG GGATGCCAGT CATTTACCAT 
GGGCACACCC TCACCACCAA GATTAAGTTC TCAGATGTCC TGCACACCAT CAAGGAGCAC 
GCGTTCGTAG CCTCAGAGTA CCCTGTCATC CTGTCCATCG AGGACCACTG CAGCATTGCC 
CAGCAGAGGA ACATGGCCCA GCACTTCAGG AAGGTGCTCG GTGACACGCT CCTCACCAAG 
CCCGTGGACA TTGCCGCTGA TGGGCTCCCT TCTCCCAACC AGCTCAAGAG GAAGATCCTG 
ATTAAGCATA AGAAGCTGGC TGAGGGCAGT GCCTATGAGG AGGTGCCTAC CTCTGTGATG 
TACTCTGAGA ATGACATCAG TAACTCCATC AAGAATGGTA TCCTCTACTT GGAGGACCCC 
GTGAATCATG AGTGGTACCC CCACTACTTT GTTCTGACTA GCAGCAAGAT CTACTACTCT 
GAGGAGACCA GCAGTGACCA GGGAAATGAG GATGAAGAGG AGCCGAAGGA GGCCAGTGGC 
AGCACAGAGC TGCACTCGAG CGAGAAGTGG TTCCACGGGA AGCTCGGGGC TGGGCGCGAC 
GGGCGGCACA TTGCTGAGCG CCTGCTCACC GAGTACTGCA TAGAGACTGG GGCTCCCGAT 
GGCTCCTTCC TAGTGCGAGA AAGTGAGACC TTCGTGGGGG ACTACACGCT GTCTTTTTGG 
CGGAATGGGA AAGTCCAGCA CTGCCGTATC CACTCCCGGC AGGATGCTGG GACTCCTAAG 
TTCTTCTTGA CAGATAACCT TGTCTTTGAC TCTCTCTATG ACCTCATCAC ACATTATCAG 
CAAGTGCCCC TGCGCTGCAA TGAGTTTGAG ATGCGCCTTT CAGAGCCTGT TCCACAGACG 
AATGCCCATG AGAGCAAAGA GTGGTACCAC GCAAGCCTGA CTAGAGCTCA GGCTGAACAC 
ATGCTGATGC GAGTACCCCG TGATGGGGCC TTCCTGGTGC GGAAGCGCAA CGAGCCCAAC 
TCCTATGCCA TCTCTTTCCG GGCTGAGGGA AAGATCAAGC ACTGCCGAGT ACAGCAGGAA 
GGCCAGACTG TGATGCTGGG GAACTCTGAG TTTGACAGCC TGGTCGACCT CATCAGCTAC 
TATGAGAAGC ATCCCCTGTA CCGCAAAATG AAACTGCGCT ACCCCATCAA CGAGGAGGCG 
CTGGAGAAGA TTGGGACAGC TGAACCCGAT TATGGGGCAC TGTATGAGGG CCGCAACCCT 
GGTTTCTATG TGGAGGCCAA CCCTATGCCA ACTTTCAAGT GTGCAGTAAA AGCTCTCTTC 
GACTACAAGG CCCAGAGAGA GGATGAGCTG ACTTTTACCA AGAGCGCCAT CATCCAGAAT 
GTGGAAAAGC AAGATGGTGG CTGGTGGCGT GGGGACTATG GTGGGAAGAA GCAGCTGTGG 
TTCCCCTCAA ACTATGTGGA AGAGATGATC AATCCAGCAA TCCTAGAGCC GGAGAGGGAG 
CATCTGGATG AGAACAGCCC ACTGGGGGAC TTGCTGCGAG GGGTCTTAGA TGTGCCAGCC 
TGCCAGATCG CCATTCGTCC TGAGGGCAAA AACAACCGGC TCTTCGTCTT CTCCATCAGC 
ATGCCGTCAG TGGCTCAGTG GTCCCTAGAC GTTGCCGCTG ACTCACAGGA GGAGTTGCAG 
GACTGGGTGA AAAAGATCCG TGAAGTTGCC CAGACTGCAG ATGCCAGGCT TACTGAGGGG 
AAGATGATGG AGAGGAGGAA GAAGATCGCC TTGGAGCTCT CCGAGCTCGT GGTCTACTGC 
CGGCCTGTTC CCTTTGACGA AGAGAAGATT GGCACAGAAC GCGCTTGTTA CCGGGACATG 
TCCTCCTTTC CGGAAACCAA GGCTGAGAAG TATGTGAACA AGGCCAAAGG CAAGAAGTTC 
CTCCAGTACA ACCGGCTGCA GCTCTCTCGC ATCTACCCTA AGGGTCAGAG GCTGGACTCC 
TCCAATTATG ACCCTCTGCC CATGTGGATC TGTGGCAGCC AGCTTGTAGC TCTCAATTTT 
CAGACCCCAG ACAAGCCTAT GCAGATGAAC CAGGCCCTCT TCATGGCTGG TGGACACTGT 
GGCTATGTGC TGCAGCCAAG CACCATGAGA GATGAAGCCT TTGACCCCTT TGATAAGAGC 
AGTCTCCGAG GTCTGGAGCC CTGTGTCATT TGCATTGAGG TGCTGGGGGC CAGGCATCTG 
CCGAAGAATG GCCGGGGTAT TGTGTGTCCT TTCGTGGAGA TTGAAGTGGC TGGGGCAGAG 
TACGACAGCA CCAAGCAGAA GACAGAGTTT GTAGTGGACA ATGGACTGAA CCCTGTGTGG 
CCTGCAAAGC CCTTCCACTT CCAGATCAGT AACCCAGAGT TTGCCTTTCT GCGCTTTGTG 
GTGTATGAGG AAGACATGTT TAGTGACCAG AACTTCTTGG CTCAGGCTAC TTTCCCAGTA 
AAAGGCCTGA AGACAGGATA CAGAGCAGTG CCTTTGAAGA ACAACTACAG TGAAGACCTG 
GAGTTGGCCT CCCTGCTCAT CAAGATTGAC ATTTTCCCTG CTAAGGAGAA TGGTGACCTC 
AGCCCTTTCA GTGGTACATC CCTAAGGGAA CGGGCCTCAG ATGCCTCCAG CCAGCTGTTC 
CATGTCCGGG CCCGGGAAGG GTCCTTTGAA GCCAGATACC AGCAGCCATT TGAAGACTTC 
CGCATCTCGC AGGAGCATCT CGCAGACCAT TTTGACAGTC GGGAACGAAG GGCCCCAAGA 
AGGACTCGGG TCAATGGAGA CAACCGCCTC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Forebrain-specific ablation of phospholipase C?1 causes manic-like behavior.
Molecular psychiatry22(10)1473-1482(2017 Oct)
Yang YR,Jung JH,Kim SJ,Hamada K,Suzuki A,Kim HJ,Lee JH,Kwon OB,Lee YK,Kim J,Kim EK,Jang HJ,Kang DS,Choi JS,Lee CJ,Marshall J,Koh HY,Kim CJ,Seok H,Kim SH,Choi JH,Choi YB,Cocco L,Ryu SH,Kim JH,Suh PG

Phospholipase C?1 Mediates Intima Formation Through Akt-Notch1 Signaling Independent of the Phospholipase Activity.
Journal of the American Heart Association6(7)(2017 Jul)
Jiang D,Zhuang J,Peng W,Lu Y,Liu H,Zhao Q,Chi C,Li X,Zhu G,Xu X,Yan C,Xu Y,Ge J,Pang J

c-Jun enhances intestinal epithelial restitution after wounding by increasing phospholipase C-?1 transcription.
American journal of physiology. Cell physiology312(4)C367-C375(2017 Apr)
Wang PY,Wang SR,Xiao L,Chen J,Wang JY,Rao JN

MiR-30s Family Inhibit the Proliferation and Apoptosis in Human Coronary Artery Endothelial Cells Through Targeting the 3'UTR Region of ITGA4 and PLCG1.
Journal of cardiovascular pharmacology68(5)327-333(2016 Nov)
Ma F,Li T,Zhang H,Wu G

Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin ?1 and phosphorylation of downstream phospholipase C?1.
Molecular medicine reports14(3)2457-64(2016 Sep)
Gao G,He J,Nong L,Xie H,Huang Y,Xu N,Zhou D