PLCG1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLCG1
Entrez Gene ID	281987
Full Name	phospholipase C gamma 1
General protein information	Preferred Names phospholipase C gamma 1 Names 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 PLC-148 PLC-II PLC-gamma-1 phosphoinositide phospholipase C phosphoinositide phospholipase C-gamma-1 phospholipase C-II
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174425.3	NP_776850.1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Plcg1	NP_037319.1
Pan troglodytes (chimpanzee)	PLCG1	XP_514650.3
Bos taurus (cattle)	PLCG1	NP_776850.1
Drosophila melanogaster (fruit fly)	sl	NP_476726.2
Mus musculus (house mouse)	Plcg1	NP_067255.2
Homo sapiens (human)	PLCG1	NP_002651.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011152	XP_309496.4
Caenorhabditis elegans (roundworm)	plc-3	NP_496205.2
	PLCG1	XP_001087295.2
Canis lupus familiaris (dog)	PLCG1	XP_005635117.1
Gallus gallus (chicken)	PLCG1	XP_004947069.1
Danio rerio (zebrafish)	plcg1	NP_919388.1
Arabidopsis thaliana (thale cress)	PLC2	NP_187464.1
Arabidopsis thaliana (thale cress)	AT3G55940	NP_191153.1

Gene Ontology
Bibliography

Related articles in PubMed

Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1.
Min L, Joseph RE, Fulton DB, Andreotti AH
Proceedings of the National Academy of Sciences of the United States of America106(50)21143-8(2009 Dec)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation.
Laram?e M, Chabot C, Cloutier M, Stenne R, Holgado-Madruga M, Wong AJ, Royal I
The Journal of biological chemistry282(11)7758-69(2007 Mar)

Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain.
DeBell K, Graham L, Reischl I, Serrano C, Bonvini E, Rellahan B
Molecular and cellular biology27(3)854-63(2007 Feb)

Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains.
Braiman A, Barda-Saad M, Sommers CL, Samelson LE
The EMBO journal25(4)774-84(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PLC-gamma1 is regulated via a novel autoinhibitory mechanism involving its carboxy-terminal Src homology (SH2C) domain.
Title: Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain.

Tyrosine775 is identified as a new, functionally important phosphorylation site on PLC gamma 1; phosphorylation of both Y775 and Y783 is required for PLC gamma 1 activation as measured by antigen receptor-induced Ca2+ flux, NF-AT and AP-1 activation.
Title: A new tyrosine phosphorylation site in PLC gamma 1: the role of tyrosine 775 in immune receptor signaling.

This study is the first to indicate that PLC gamma 1 is expressed in bovine adrenal chromaffin cells and has the potential to be activated.
Title: The tyrosine [correction of tryrosine] phosphorylation and cytoskeletal translocation of phospholipase C gamma 1 in bovine adrenal medullary chromaffin cells.

The following PLCG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLCG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa00200	NM_174425.3 Latest version!	Bos taurus phospholipase C gamma 1 (PLCG1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$713.30 $1019.00

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLCG1 ( NM_174425.3 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776850.1 Bos taurus phospholipase C gamma 1 (PLCG1), mRNA.

Price & Availability↑

CloneID	OBa00200
Clone ID Related Accession (Same CDS sequence)	NM_174425.3
Accession Version	NM_174425.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Bos taurus(cattle)
Product	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y00301.1. On Feb 21, 2013 this sequence version replaced NM_174425.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y00301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGCG CCGCGTCCCC CTGCGCCAAC GGCTGCGGGC CCAGTGCGCC CTCGGACGCC 
GAGGTGGTGC ACCTCTGCCG CAGCCTCGAG GTGGGCACCG TCATGACTTT GTTCTACTCC 
AAGAAGTCGC AGCGGCCCGA GCGGAAGACC TTCCAGGTCA AGCTGGAGAC GCGGCAGATC 
ACGTGGAGCC GAGGCGCCGA CAAGATAGAG GGGGCCATTG ACATTCGTGA AATCAAGGAG 
ATCCGCCCAG GGAAGACCTC ACGGGACTTC GATCGCTACC AAGAGGATCC TGCTTTTCGA 
CCGGACCAGT CCCACTGCTT CGTCATCCTG TATGGAATGG AATTCCGCCT GAAGACCCTG 
AGCCTCCAAG CCACGTCTGA GGACGAAGTG AACATGTGGA TCAGGGGCCT GACTTGGCTG 
ATGGAGGACA CGTTGCAGGC AGCCACACCC CTGCAGATTG AGAGGTGGCT GCGGAAGCAG 
TTCTACTCAG TGGACCGGAA CCGTGAGGAC CGGATATCGG CCAAGGACCT GAAGAACATG 
CTGTCCCAGG TCAACTACCG GGTCCCCAAC ATGCGCTTCC TCCGGGAGCG GCTGACGGAC 
CTGGAGCAGC GCACCAGTGA CATCACCTAC GGGCAGTTTG CACAGCTGTA CCGCAGCCTC 
ATGTACAGCG CCCAGAAGAC GATGGACCTT CCTTTCCTGG AAGCCAGCGC CCTGAGGGCG 
GGGGAGCGGC CGGAGCTGTG CCGGGTGTCC CTTCCTGAGT TCCAGCAGTT CCTCCTCGAG 
TACCAAGGGG AGCTGTGGGC GGTGGACCGG CTCCAGGTGC AGGAGTTCAT GCTCAGCTTC 
CTCCGAGACC CCTTGCGAGA GATTGAGGAG CCTTACTTCT TCCTGGACGA GTTCGTCACC 
TTCCTGTTCT CCAAGGAGAA CAGCATATGG AACTCGCAGC TAGACGAGGT GTGCCCCGAC 
ACCATGAACA ACCCCCTGTC CCACTACTGG ATCTCCTCCT CGCACAACAC GTACCTGACC 
GGGGACCAGT TCTCCAGCGA GTCCTCCCTG GAAGCCTACG CTCGCTGCCT GCGGATGGGC 
TGCCGTTGCA TTGAGTTGGA CTGCTGGGAC GGCCCGGATG GGATGCCGGT CATTTACCAT 
GGACACACTC TGACCACCAA GATCAAGTTC TCAGACGTCC TGCACACCAT CAAGGAGCAC 
GCCTTTGTGG CCTCAGAGTA CCCGGTCATC CTGTCCATCG AGGACCACTG CAGCATTGCC 
CAGCAGAGGA ACATGGCCCA GTATTTCAAA AAGGTGCTTG GGGACACACT CCTCACCAAG 
CCCGTGGATA TTGCAGCCGA CGGGCTCCCC TCCCCCAACC AGCTCAAGAG GAAGATCCTT 
ATCAAGCACA AGAAGTTGGC TGAGGGCAGT GCCTACGAGG AGGTGCCAAC ATCGGTGATG 
TACTCTGAGA ACGACATCAG CAACTCCATC AAGAATGGCA TCCTCTACCT GGAAGACCCT 
GTGAACCATG AGTGGTACCC CCACTACTTC GTCCTGACCA GCAGCAAGAT CTACTACTCG 
GAGGAGACCA GCAGCGACCA GGGCAACGAG GATGAGGAGG AGCCCAAGGA GGCCAGTGGC 
AGCACAGAGC TGCACTCCAA CGAGAAGTGG TTCCACGGGA AGCTTGGGGC GGGCCGGGAT 
GGGCGGCACA TCGCCGAGCG CCTGCTCACG GAGTACTGCA TTGAGACCGG GGCCCCCGAC 
GGCTCCTTCC TTGTGCGCGA GAGCGAGACC TTTGTGGGCG ACTACACTCT GTCCTTCTGG 
CGGAATGGCA AAGTGCAGCA CTGCCGGATC CACTCCCGGC AGGACGCAGG CACCCCCAAG 
TTCTTCCTGA CGGACAACCT CGTCTTCGAC TCCCTCTATG ACCTCATCAC GCACTACCAG 
CAGGTGCCCC TGCGCTGCAA CGAATTTGAG ATGCGCCTCT CAGAGCCGGT CCCGCAGACC 
AACGCGCACG AGAGCAAAGA GTGGTACCAC GCCAGCCTGA CCAGAGCGCA GGCCGAGCAC 
ATGCTGATGC GTGTACCCAG GGACGGGGCC TTCCTGGTGC GGAAACGGAA CGAGCCCAAC 
TCCTACGCCA TCTCCTTCCG GGCTGAGGGC AAGATCAAGC ACTGCCGCGT CCAGCAGGAG 
GGCCAGACCG TGATGCTGGG CAACTCAGAG TTTGACAGCC TTGTCGACCT CATCAGCTAC 
TACGAGAAGC ACCCACTGTA CCGCAAGATG AAGCTGCGCT ACCCCATCAA CGAGGAGGCT 
CTGGAGAAGA TCGGCACAGC TGAGCCTGAC TACGGCGCGC TGTACGAGGG CCGCAACCCT 
GGCTTCTATG TGGAGGCGAA CCCCATGCCC ACGTTCAAGT GCGCCGTCAA AGCTCTCTTC 
GACTACAAAG CGCAGCGGGA GGACGAGCTG ACATTCACCA AGAGTGCCAT CATCCAGAAC 
GTGGAGAAGC AGGAGGGAGG CTGGTGGCGG GGTGACTACG GCGGGAAGAA GCAGCTGTGG 
TTCCCTTCAA ACTATGTGGA GGAAATGGTC AGCCCGGCGG CCCTGGAGCC CGAGAGGGAG 
CACTTGGACG AGAACAGCCC ACTCGGGGAC TTGCTCCGGG GGGTCCTGGA TGTGCCAGCT 
TGTCAGATAG CCGTCCGTCC CGAGGGCAAG AACAACCGGC TGTTCGTCTT CTCCATCAGC 
ATGGCCTCGG TGGCACACTG GTCCCTGGAT GTGGCTGCCG ACTCGCAGGA AGAGCTGCAG 
GACTGGGTGA AGAAGATCCG GGAGGTGGCG CAGACAGCGG ATGCCAGGCT CACCGAGGGC 
AAGATGATGG AGCGGAGGAA GAAGATCGCC CTAGAGCTCT CAGAGCTCGT CGTCTACTGC 
CGGCCTGTCC CTTTCGACGA AGAGAAGATT GGCACCGAAC GGGCCTGCTA CCGCGACATG 
TCGTCCTTCC CGGAGACCAA GGCCGAGAAG TACGTGAACA AGGCCAAAGG CAAGAAGTTC 
CTCCAGTACA ACCGCCTGCA GCTCTCCCGC ATCTACCCTA AGGGCCAGCG GCTGGACTCC 
TCCAATTACG ACCCCCTGCC CATGTGGATC TGCGGCAGCC AGCTTGTGGC CCTCAACTTC 
CAGACCCCAG ACAAACCCAT GCAGATGAAC CAGGCCCTGT TCCTGGCCGG CGGGCACTGT 
GGCTATGTGC TGCAGCCCAG CGTCATGCGC GATGAGGCCT TCGATCCCTT TGACAAGAGC 
AGCCTCCGCG GGCTGGAGCC GTGCGCCATC TGCATCGAGG TGCTGGGGGC CCGGCACCTG 
CCGAAGAACG GCCGAGGCAT CGTGTGTCCT TTTGTGGAGA TCGAGGTGGC CGGAGCCGAG 
TATGACAGCA TCAAGCAGAA GACAGAGTTT GTGGTGGACA ATGGACTGAA CCCCGTGTGG 
CCAGCCAAGC CCTTCCACTT CCAGATTAGT AACCCCGAGT TCGCCTTCCT GCGCTTCGTG 
GTCTATGAGG AGGACATGTT TAGTGACCAG AACTTCCTAG CTCAGGCTAC CTTCCCAGTG 
AAGGGTCTGA AGACAGGCTA CAGAGCGGTG CCTCTGAAGA ACAACTACAG TGAGGGCCTG 
GAGCTGGCCT CCCTGCTCGT CAAGATTGAC GTGTTCCCTG CCAAGCAGGA GAACGGCGAC 
CTCAGCCCCT TCGGGGGTGC GTCCCTGCGG GAGCGGAGCT GTGACGCCTC GGGCCCGCTG 
TTCCACGGCC GGGCCCGGGA GGGCTCCTTT GAAGCTCGCT ACCAGCAGCC CTTTGAGGAC 
TTCCGCATCT CCCAGGAGCA TCTCGCAGAC CATTTTGACG GTCGGGATCG CAGGACCCCA 
CGCAGGACTC GGGTCAACGG AGACAACCGC CTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776850.1
CDS	29..3904
Translation	MAGAASPCANGCGPSAPSDAEVVHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIRGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRTSDITYGQFAQLYRSLMYSAQKTMDLPFLEASALRAGERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSIWNSQLDEVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASGSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAVRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFLAGGHCGYVLQPSVMRDEAFDPFDKSSLRGLEPCAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEGLELASLLVKIDVFPAKQENGDLSPFGGASLRERSCDASGPLFHGRAREGSFEARYQQPFEDFRISQEHLADHFDGRDRRTPRRTRVNGDNRL

Target ORF information:

RefSeq Version	NM_174425.3
Organism	Bos taurus(cattle)
Definition	Bos taurus phospholipase C gamma 1 (PLCG1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174425.3

ORF Insert Sequence:

ATGGCGGGCG CCGCGTCCCC CTGCGCCAAC GGCTGCGGGC CCAGTGCGCC CTCGGACGCC 
GAGGTGGTGC ACCTCTGCCG CAGCCTCGAG GTGGGCACCG TCATGACTTT GTTCTACTCC 
AAGAAGTCGC AGCGGCCCGA GCGGAAGACC TTCCAGGTCA AGCTGGAGAC GCGGCAGATC 
ACGTGGAGCC GAGGCGCCGA CAAGATAGAG GGGGCCATTG ACATTCGTGA AATCAAGGAG 
ATCCGCCCAG GGAAGACCTC ACGGGACTTC GATCGCTACC AAGAGGATCC TGCTTTTCGA 
CCGGACCAGT CCCACTGCTT CGTCATCCTG TATGGAATGG AATTCCGCCT GAAGACCCTG 
AGCCTCCAAG CCACGTCTGA GGACGAAGTG AACATGTGGA TCAGGGGCCT GACTTGGCTG 
ATGGAGGACA CGTTGCAGGC AGCCACACCC CTGCAGATTG AGAGGTGGCT GCGGAAGCAG 
TTCTACTCAG TGGACCGGAA CCGTGAGGAC CGGATATCGG CCAAGGACCT GAAGAACATG 
CTGTCCCAGG TCAACTACCG GGTCCCCAAC ATGCGCTTCC TCCGGGAGCG GCTGACGGAC 
CTGGAGCAGC GCACCAGTGA CATCACCTAC GGGCAGTTTG CACAGCTGTA CCGCAGCCTC 
ATGTACAGCG CCCAGAAGAC GATGGACCTT CCTTTCCTGG AAGCCAGCGC CCTGAGGGCG 
GGGGAGCGGC CGGAGCTGTG CCGGGTGTCC CTTCCTGAGT TCCAGCAGTT CCTCCTCGAG 
TACCAAGGGG AGCTGTGGGC GGTGGACCGG CTCCAGGTGC AGGAGTTCAT GCTCAGCTTC 
CTCCGAGACC CCTTGCGAGA GATTGAGGAG CCTTACTTCT TCCTGGACGA GTTCGTCACC 
TTCCTGTTCT CCAAGGAGAA CAGCATATGG AACTCGCAGC TAGACGAGGT GTGCCCCGAC 
ACCATGAACA ACCCCCTGTC CCACTACTGG ATCTCCTCCT CGCACAACAC GTACCTGACC 
GGGGACCAGT TCTCCAGCGA GTCCTCCCTG GAAGCCTACG CTCGCTGCCT GCGGATGGGC 
TGCCGTTGCA TTGAGTTGGA CTGCTGGGAC GGCCCGGATG GGATGCCGGT CATTTACCAT 
GGACACACTC TGACCACCAA GATCAAGTTC TCAGACGTCC TGCACACCAT CAAGGAGCAC 
GCCTTTGTGG CCTCAGAGTA CCCGGTCATC CTGTCCATCG AGGACCACTG CAGCATTGCC 
CAGCAGAGGA ACATGGCCCA GTATTTCAAA AAGGTGCTTG GGGACACACT CCTCACCAAG 
CCCGTGGATA TTGCAGCCGA CGGGCTCCCC TCCCCCAACC AGCTCAAGAG GAAGATCCTT 
ATCAAGCACA AGAAGTTGGC TGAGGGCAGT GCCTACGAGG AGGTGCCAAC ATCGGTGATG 
TACTCTGAGA ACGACATCAG CAACTCCATC AAGAATGGCA TCCTCTACCT GGAAGACCCT 
GTGAACCATG AGTGGTACCC CCACTACTTC GTCCTGACCA GCAGCAAGAT CTACTACTCG 
GAGGAGACCA GCAGCGACCA GGGCAACGAG GATGAGGAGG AGCCCAAGGA GGCCAGTGGC 
AGCACAGAGC TGCACTCCAA CGAGAAGTGG TTCCACGGGA AGCTTGGGGC GGGCCGGGAT 
GGGCGGCACA TCGCCGAGCG CCTGCTCACG GAGTACTGCA TTGAGACCGG GGCCCCCGAC 
GGCTCCTTCC TTGTGCGCGA GAGCGAGACC TTTGTGGGCG ACTACACTCT GTCCTTCTGG 
CGGAATGGCA AAGTGCAGCA CTGCCGGATC CACTCCCGGC AGGACGCAGG CACCCCCAAG 
TTCTTCCTGA CGGACAACCT CGTCTTCGAC TCCCTCTATG ACCTCATCAC GCACTACCAG 
CAGGTGCCCC TGCGCTGCAA CGAATTTGAG ATGCGCCTCT CAGAGCCGGT CCCGCAGACC 
AACGCGCACG AGAGCAAAGA GTGGTACCAC GCCAGCCTGA CCAGAGCGCA GGCCGAGCAC 
ATGCTGATGC GTGTACCCAG GGACGGGGCC TTCCTGGTGC GGAAACGGAA CGAGCCCAAC 
TCCTACGCCA TCTCCTTCCG GGCTGAGGGC AAGATCAAGC ACTGCCGCGT CCAGCAGGAG 
GGCCAGACCG TGATGCTGGG CAACTCAGAG TTTGACAGCC TTGTCGACCT CATCAGCTAC 
TACGAGAAGC ACCCACTGTA CCGCAAGATG AAGCTGCGCT ACCCCATCAA CGAGGAGGCT 
CTGGAGAAGA TCGGCACAGC TGAGCCTGAC TACGGCGCGC TGTACGAGGG CCGCAACCCT 
GGCTTCTATG TGGAGGCGAA CCCCATGCCC ACGTTCAAGT GCGCCGTCAA AGCTCTCTTC 
GACTACAAAG CGCAGCGGGA GGACGAGCTG ACATTCACCA AGAGTGCCAT CATCCAGAAC 
GTGGAGAAGC AGGAGGGAGG CTGGTGGCGG GGTGACTACG GCGGGAAGAA GCAGCTGTGG 
TTCCCTTCAA ACTATGTGGA GGAAATGGTC AGCCCGGCGG CCCTGGAGCC CGAGAGGGAG 
CACTTGGACG AGAACAGCCC ACTCGGGGAC TTGCTCCGGG GGGTCCTGGA TGTGCCAGCT 
TGTCAGATAG CCGTCCGTCC CGAGGGCAAG AACAACCGGC TGTTCGTCTT CTCCATCAGC 
ATGGCCTCGG TGGCACACTG GTCCCTGGAT GTGGCTGCCG ACTCGCAGGA AGAGCTGCAG 
GACTGGGTGA AGAAGATCCG GGAGGTGGCG CAGACAGCGG ATGCCAGGCT CACCGAGGGC 
AAGATGATGG AGCGGAGGAA GAAGATCGCC CTAGAGCTCT CAGAGCTCGT CGTCTACTGC 
CGGCCTGTCC CTTTCGACGA AGAGAAGATT GGCACCGAAC GGGCCTGCTA CCGCGACATG 
TCGTCCTTCC CGGAGACCAA GGCCGAGAAG TACGTGAACA AGGCCAAAGG CAAGAAGTTC 
CTCCAGTACA ACCGCCTGCA GCTCTCCCGC ATCTACCCTA AGGGCCAGCG GCTGGACTCC 
TCCAATTACG ACCCCCTGCC CATGTGGATC TGCGGCAGCC AGCTTGTGGC CCTCAACTTC 
CAGACCCCAG ACAAACCCAT GCAGATGAAC CAGGCCCTGT TCCTGGCCGG CGGGCACTGT 
GGCTATGTGC TGCAGCCCAG CGTCATGCGC GATGAGGCCT TCGATCCCTT TGACAAGAGC 
AGCCTCCGCG GGCTGGAGCC GTGCGCCATC TGCATCGAGG TGCTGGGGGC CCGGCACCTG 
CCGAAGAACG GCCGAGGCAT CGTGTGTCCT TTTGTGGAGA TCGAGGTGGC CGGAGCCGAG 
TATGACAGCA TCAAGCAGAA GACAGAGTTT GTGGTGGACA ATGGACTGAA CCCCGTGTGG 
CCAGCCAAGC CCTTCCACTT CCAGATTAGT AACCCCGAGT TCGCCTTCCT GCGCTTCGTG 
GTCTATGAGG AGGACATGTT TAGTGACCAG AACTTCCTAG CTCAGGCTAC CTTCCCAGTG 
AAGGGTCTGA AGACAGGCTA CAGAGCGGTG CCTCTGAAGA ACAACTACAG TGAGGGCCTG 
GAGCTGGCCT CCCTGCTCGT CAAGATTGAC GTGTTCCCTG CCAAGCAGGA GAACGGCGAC 
CTCAGCCCCT TCGGGGGTGC GTCCCTGCGG GAGCGGAGCT GTGACGCCTC GGGCCCGCTG 
TTCCACGGCC GGGCCCGGGA GGGCTCCTTT GAAGCTCGCT ACCAGCAGCC CTTTGAGGAC 
TTCCGCATCT CCCAGGAGCA TCTCGCAGAC CATTTTGACG GTCGGGATCG CAGGACCCCA 
CGCAGGACTC GGGTCAACGG AGACAACCGC CTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1.
Proceedings of the National Academy of Sciences of the United States of America106(50)21143-8(2009 Dec)
Min L,Joseph RE,Fulton DB,Andreotti AH

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation.
The Journal of biological chemistry282(11)7758-69(2007 Mar)
Laram?e M,Chabot C,Cloutier M,Stenne R,Holgado-Madruga M,Wong AJ,Royal I

Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain.
Molecular and cellular biology27(3)854-63(2007 Feb)
DeBell K,Graham L,Reischl I,Serrano C,Bonvini E,Rellahan B

Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains.
The EMBO journal25(4)774-84(2006 Feb)
Braiman A,Barda-Saad M,Sommers CL,Samelson LE

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PLCG1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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