Plcg1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Plcg1
Entrez Gene ID	18803
Full Name	phospholipase C, gamma 1
Synonyms	AI894140,Cded,Plc-1,Plc-gamma1,Plcg-1
General protein information	Preferred Names phospholipase C, gamma 1 Names 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 PLC-gamma-1 cell differentiation and embryonic development phosphoinositide phospholipase C-gamma-1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2 H2\|2 80.97 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_021280.3	NP_067255.2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Plcg1	NP_037319.1
Pan troglodytes (chimpanzee)	PLCG1	XP_514650.3
Bos taurus (cattle)	PLCG1	NP_776850.1
Drosophila melanogaster (fruit fly)	sl	NP_476726.2
Mus musculus (house mouse)	Plcg1	NP_067255.2
Homo sapiens (human)	PLCG1	NP_002651.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011152	XP_309496.4
Caenorhabditis elegans (roundworm)	plc-3	NP_496205.2
	PLCG1	XP_001087295.2
Canis lupus familiaris (dog)	PLCG1	XP_005635117.1
Gallus gallus (chicken)	PLCG1	XP_004947069.1
Danio rerio (zebrafish)	plcg1	NP_919388.1
Arabidopsis thaliana (thale cress)	PLC2	NP_187464.1
Arabidopsis thaliana (thale cress)	AT3G55940	NP_191153.1

Gene Ontology
Bibliography

Related articles in PubMed

FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate.
Xu J, Huang Z, Wang W, Tan X, Li H, Zhang Y, Tian W, Hu T, Chen YP
Journal of dental research22034517750141(2018 Jan)

Dysregulated PDGFR? signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification.
He F, Soriano P
Development (Cambridge, England)144(21)4026-4036(2017 11)

PLC?-dependent mTOR signalling controls IL-7-mediated early B cell development.
Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, Broeckel U, Aggarwal P, Turner A, Neale G, Guy C, Zhu N, Chi H, Wen R, Wang D
Nature communications8(1)1457(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Syk-induced signals in bone marrow stromal cell lines are mediated by phospholipase C gamma1 (PLCgamma1) in osteogenesis and PLCgamma2 in adipogenesis.
Title: Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.

Findings provide evidence that PLCgamma1 is critical for synaptic function and plasticity and that the loss of PLCgamma1 from the forebrain results in manic-like behavior.
Title: Forebrain-specific ablation of phospholipase C?1 causes manic-like behavior.

this study shows that PLC-gamma1 contributes to protective activity of LAT activity in vivo
Title: LAT alleviates Th2/Treg imbalance in an OVA-induced allergic asthma mouse model through LAT-PLC-?1 interaction.

study shows that PLCgamma1 controls osteoclast numbers via a CSF-1-dependent DAG/beta-catenin/cyclinD1 pathway.
Title: Phospholipase C?1 (PLC?1) Controls Osteoclast Numbers via Colony-stimulating Factor 1 (CSF-1)-dependent Diacylglycerol/?-Catenin/CyclinD1 Pathway.

Knock-down of PLC-gamma-1 induced foreign body giant cell formation.PLC-gamma-1-deficiency caused a decrease in RUNX1 and subsequent PU.1 upregulation while subsequent rescue of RUNX1 in sh-PLC-gamma-1-transfected cells strongly inhibited foreign body giant cell formation.
Title: Phospholipase C?1 suppresses foreign body giant cell formation by maintaining RUNX1 expression in macrophages.

The following Plcg1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plcg1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu15966	NM_021280.3 Latest version!	Mus musculus phospholipase C, gamma 1 (Plcg1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Plcg1 ( NM_021280.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067255.2 Mus musculus phospholipase C, gamma 1 (Plcg1), mRNA.

Price & Availability↑

CloneID	OMu15966
Clone ID Related Accession (Same CDS sequence)	NM_021280.3
Accession Version	NM_021280.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Mus musculus(house mouse)
Product	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL590389.8. On Nov 17, 2006 this sequence version replaced NM_021280.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065091.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGCG TCGCGACCCC CTGCGCCAAC GGCTGCGGGC CTGGCGCACC CTCCGAAGCC 
GAGGTGCTGC ACCTCTGCCG CAGCCTCGAG GTGGGCACCG TCATGACTTT GTTCTACTCC 
AAGAAGTCGC AGCGGCCAGA ACGGAAGACC TTCCAGGTCA AGTTGGAGAC GCGCCAGATC 
ACATGGAGCC GCGGCGCGGA CAAAATCGAG GGGTCCATTG ATATCCGAGA AATCAAGGAG 
ATCCGTCCAG GGAAGACTTC TCGGGACTTT GACCGCTACC AAGAAGACCC TGCCTTCCGG 
CCAGATCAAT CACACTGCTT TGTCATCCTC TATGGAATGG AATTCCGCTT GAAGACCCTG 
AGCCTGCAAG CCACATCTGA GGATGAAGTG AACATGTGGA TCAAGGGCTT AACTTGGCTA 
ATGGAGGATA CACTGCAGGC AGCCACACCC CTGCAAATTG AGAGGTGGCT CCGGAAGCAG 
TTCTACTCAG TGGATCGTAA CCGAGAGGAT CGTATATCAG CCAAGGACTT GAAGAACATG 
CTGTCTCAGG TCAACTACCG AGTCCCCAAT ATGCGCTTCC TCCGAGAGCG GCTGACGGAC 
CTTGAACAGC GCAGCGGGGA CATCACCTAC GGGCAGTTTG CTCAGCTGTA CCGCAGCCTC 
ATGTACAGCG CCCAGAAGAC GATGGACCTT CCCTTCTTGG AAACCAACGC TTTGAGGACT 
GGAGAGCGTC CGGAGCATTG CCAGGTGTCC CTTTCTGAGT TCCAGCAGTT CCTCCTTGAA 
TACCAGGGGG AGCTGTGGGC TGTCGACCGG CTCCAGGTGC AGGAATTCAT GCTCAGCTTC 
CTTCGAGACC CCTTGCGAGA GATTGAGGAG CCATACTTCT TCTTGGATGA GCTTGTCACC 
TTCCTGTTCT CCAAAGAGAA CAGCGTGTGG AACTCACAGC TGGATGCTGT GTGCCCGGAC 
ACCATGAACA ACCCACTCTC TCACTATTGG ATCTCCTCCT CACATAATAC GTACCTGACT 
GGGGACCAGT TCTCCAGTGA GTCCTCCCTG GAAGCCTATG CTCGCTGCCT GAGGATGGGC 
TGTCGCTGCA TTGAGTTGGA CTGCTGGGAT GGGCCAGATG GGATGCCAGT CATTTACCAT 
GGGCACACTC TCACCACCAA GATCAAGTTC TCTGACGTCC TGCACACCAT CAAGGAGCAT 
GCTTTCGTAG CCTCAGAGTA CCCAGTCATC CTGTCCATCG AGGACCACTG CAGCATTGCC 
CAGCAGAGAA ACATGGCTCA GCACTTCAGA AAGGTGCTTG GCGACACACT CCTTACCAAG 
CCTGTGGACA TTGCTGCTGA TGGCCTTCCT TCTCCCAACC AGCTCAGGAG GAAGATCCTT 
ATTAAGCACA AGAAGCTGGC TGAGGGCAGT GCCTATGAGG AGGTGCCTAC CTCTGTGATG 
TACTCCGAGA ATGACATCAG TAACTCCATC AAGAATGGTA TCCTCTACTT GGAGGACCCC 
GTGAATCATG AGTGGTATCC CCACTACTTC GTTCTGACTA GCAGCAAGAT CTACTACTCT 
GAGGAGACCA GCAGTGACCA GGGCAATGAG GATGAAGAGG AGCCGAAGGA GGCCAGCAGC 
AGCACAGAGC TGCACTCGAG TGAGAAGTGG TTCCACGGGA AGCTCGGGGC TGGACGTGAC 
GGGCGGCACA TTGCTGAGCG CCTGCTCACT GAGTACTGCA TAGAGACTGG GGCTCCTGAT 
GGCTCCTTCC TAGTGCGAGA AAGTGAGACC TTCGTGGGTG ACTACACGCT GTCTTTCTGG 
CGGAATGGGA AAGTCCAGCA CTGCCGCATC CACTCCCGGC AGGATGCTGG GACTCCTAAG 
TTCTTCTTGA CAGATAACCT TGTCTTTGAC TCTCTCTATG ACCTCATCAC ACATTATCAG 
CAAGTACCCC TGCGCTGCAA TGAGTTTGAG ATGCGCCTTT CAGAGCCTGT TCCACAGACG 
AATGCCCATG AGAGCAAAGA GTGGTACCAC GCAAGCCTGA CTAGAGCTCA GGCTGAACAT 
ATGCTGATGC GAGTGCCCCG GGATGGGGCC TTCCTGGTGC GGAAACGCAA TGAGCCTAAC 
TCATATGCCA TCTCTTTCCG GGCTGAGGGA AAGATCAAGC ACTGCCGAGT ACAGCAGGAA 
GGCCAGACAG TGATGCTGGG GAACTCTGAG TTTGACAGCC TGGTTGACCT CATCAGCTAC 
TATGAGAAGC ACCCCCTGTA CCGCAAAATG AAGCTACGCT ACCCCATCAA CGAGGAGGCA 
CTGGAGAAGA TCGGGACAGC TGAACCCGAT TATGGGGCAC TATACGAGGG CCGCAACCCT 
GGTTTCTATG TGGAGGCAAA CCCTATGCCA ACTTTCAAGT GTGCAGTAAA AGCCCTCTTC 
GACTACAAGG CCCAGAGAGA GGATGAGCTG ACCTTCACCA AGAGTGCCAT CATCCAGAAT 
GTGGAAAAGC AAGATGGTGG CTGGTGGCGA GGGGACTATG GTGGGAAGAA GCAGCTGTGG 
TTCCCCTCAA ACTATGTGGA AGAGATGATC AATCCAGCAG TCCTAGAGCC TGAGAGGGAG 
CACCTGGATG AGAACAGCCC ACTGGGGGAC TTGCTGCGAG GGGTCTTAGA TGTGCCAGCT 
TGTCAGATCG CCATCCGTCC TGAGGGCAAA AACAACCGGC TCTTCGTCTT CTCCATCAGC 
ATGCCATCAG TGGCTCAGTG GTCCCTGGAT GTTGCAGCTG ACTCACAGGA GGAGTTACAG 
GACTGGGTGA AAAAGATCCG TGAAGTTGCC CAGACTGCAG ATGCCAGGCT CACTGAGGGA 
AAGATGATGG AGAGGAGGAA GAAGATCGCC TTGGAGCTCT CCGAGCTTGT GGTCTACTGC 
CGGCCCGTTC CCTTTGATGA AGAGAAGATT GGCACAGAAC GTGCTTGTTA CCGGGACATG 
TCCTCCTTTC CGGAAACCAA GGCTGAGAAG TATGTGAACA AGGCCAAAGG CAAGAAGTTC 
CTCCAGTACA ACCGGCTGCA GCTCTCGCGC ATCTACCCTA AGGGCCAGAG GCTAGACTCC 
TCCAATTATG ACCCTCTGCC CATGTGGATC TGCGGTAGCC AGCTTGTAGC ACTCAATTTC 
CAGACCCCAG ACAAGCCTAT GCAGATGAAC CAGGCCCTCT TCATGGCTGG TGGGCATTGT 
GGCTATGTGC TGCAGCCAAG CACCATGAGA GACGAAGCCT TTGACCCCTT TGATAAGAGC 
AGTCTCCGAG GTCTGGAACC CTGTGTCATT TGCATTGAGG TGCTGGGGGC CAGGCATCTG 
CCGAAGAATG GCCGGGGTAT TGTGTGTCCT TTTGTGGAGA TTGAGGTGGC TGGGGCTGAG 
TACGACAGCA CCAAGCAAAA GACGGAGTTT GTAGTGGACA ACGGACTGAA CCCTGTGTGG 
CCTGCTAAGC CCTTCCACTT CCAGATCAGT AACCCAGAGT TTGCCTTTCT GCGCTTTGTG 
GTGTATGAGG AAGACATGTT TAGTGACCAG AACTTCTTGG CTCAGGCTAC TTTCCCAGTA 
AAAGGCCTGA AGACAGGATA TAGAGCAGTG CCTTTGAAGA ACAACTACAG TGAAGACCTG 
GAGTTGGCCT CCCTGCTCAT CAAGATTGAC ATTTTCCCTG CTAAGGAGAA CGGTGACCTC 
AGTCCTTTCA GTGGCATATC CCTAAGGGAA CGGGCCTCAG ATGCCTCCAG CCAGCTGTTC 
CATGTCCGGG CCCGGGAAGG GTCCTTTGAA GCCAGATACC AGCAGCCATT TGAAGATTTC 
CGCATCTCGC AGGAGCATCT AGCAGACCAT TTTGACAGTC GGGAACGAAG TACTTCAGAT 
GGTCCTTCCT CAGCCACTAA CCTTATTGAG GATCCCTTAC ATGACAAGCT GTGGAAGTGC 
TCTCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067255.2
CDS	135..4043
Translation	MAGVATPCANGCGPGAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNALRTGERPEHCQVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLRRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASSSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAVLEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGISLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERSTSDGPSSATNLIEDPLHDKLWKCSL

Target ORF information:

RefSeq Version	NM_021280.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus phospholipase C, gamma 1 (Plcg1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021280.3

ORF Insert Sequence:

ATGGCGGGCG TCGCGACCCC CTGCGCCAAC GGCTGCGGGC CTGGCGCACC CTCCGAAGCC 
GAGGTGCTGC ACCTCTGCCG CAGCCTCGAG GTGGGCACCG TCATGACTTT GTTCTACTCC 
AAGAAGTCGC AGCGGCCAGA ACGGAAGACC TTCCAGGTCA AGTTGGAGAC GCGCCAGATC 
ACATGGAGCC GCGGCGCGGA CAAAATCGAG GGGTCCATTG ATATCCGAGA AATCAAGGAG 
ATCCGTCCAG GGAAGACTTC TCGGGACTTT GACCGCTACC AAGAAGACCC TGCCTTCCGG 
CCAGATCAAT CACACTGCTT TGTCATCCTC TATGGAATGG AATTCCGCTT GAAGACCCTG 
AGCCTGCAAG CCACATCTGA GGATGAAGTG AACATGTGGA TCAAGGGCTT AACTTGGCTA 
ATGGAGGATA CACTGCAGGC AGCCACACCC CTGCAAATTG AGAGGTGGCT CCGGAAGCAG 
TTCTACTCAG TGGATCGTAA CCGAGAGGAT CGTATATCAG CCAAGGACTT GAAGAACATG 
CTGTCTCAGG TCAACTACCG AGTCCCCAAT ATGCGCTTCC TCCGAGAGCG GCTGACGGAC 
CTTGAACAGC GCAGCGGGGA CATCACCTAC GGGCAGTTTG CTCAGCTGTA CCGCAGCCTC 
ATGTACAGCG CCCAGAAGAC GATGGACCTT CCCTTCTTGG AAACCAACGC TTTGAGGACT 
GGAGAGCGTC CGGAGCATTG CCAGGTGTCC CTTTCTGAGT TCCAGCAGTT CCTCCTTGAA 
TACCAGGGGG AGCTGTGGGC TGTCGACCGG CTCCAGGTGC AGGAATTCAT GCTCAGCTTC 
CTTCGAGACC CCTTGCGAGA GATTGAGGAG CCATACTTCT TCTTGGATGA GCTTGTCACC 
TTCCTGTTCT CCAAAGAGAA CAGCGTGTGG AACTCACAGC TGGATGCTGT GTGCCCGGAC 
ACCATGAACA ACCCACTCTC TCACTATTGG ATCTCCTCCT CACATAATAC GTACCTGACT 
GGGGACCAGT TCTCCAGTGA GTCCTCCCTG GAAGCCTATG CTCGCTGCCT GAGGATGGGC 
TGTCGCTGCA TTGAGTTGGA CTGCTGGGAT GGGCCAGATG GGATGCCAGT CATTTACCAT 
GGGCACACTC TCACCACCAA GATCAAGTTC TCTGACGTCC TGCACACCAT CAAGGAGCAT 
GCTTTCGTAG CCTCAGAGTA CCCAGTCATC CTGTCCATCG AGGACCACTG CAGCATTGCC 
CAGCAGAGAA ACATGGCTCA GCACTTCAGA AAGGTGCTTG GCGACACACT CCTTACCAAG 
CCTGTGGACA TTGCTGCTGA TGGCCTTCCT TCTCCCAACC AGCTCAGGAG GAAGATCCTT 
ATTAAGCACA AGAAGCTGGC TGAGGGCAGT GCCTATGAGG AGGTGCCTAC CTCTGTGATG 
TACTCCGAGA ATGACATCAG TAACTCCATC AAGAATGGTA TCCTCTACTT GGAGGACCCC 
GTGAATCATG AGTGGTATCC CCACTACTTC GTTCTGACTA GCAGCAAGAT CTACTACTCT 
GAGGAGACCA GCAGTGACCA GGGCAATGAG GATGAAGAGG AGCCGAAGGA GGCCAGCAGC 
AGCACAGAGC TGCACTCGAG TGAGAAGTGG TTCCACGGGA AGCTCGGGGC TGGACGTGAC 
GGGCGGCACA TTGCTGAGCG CCTGCTCACT GAGTACTGCA TAGAGACTGG GGCTCCTGAT 
GGCTCCTTCC TAGTGCGAGA AAGTGAGACC TTCGTGGGTG ACTACACGCT GTCTTTCTGG 
CGGAATGGGA AAGTCCAGCA CTGCCGCATC CACTCCCGGC AGGATGCTGG GACTCCTAAG 
TTCTTCTTGA CAGATAACCT TGTCTTTGAC TCTCTCTATG ACCTCATCAC ACATTATCAG 
CAAGTACCCC TGCGCTGCAA TGAGTTTGAG ATGCGCCTTT CAGAGCCTGT TCCACAGACG 
AATGCCCATG AGAGCAAAGA GTGGTACCAC GCAAGCCTGA CTAGAGCTCA GGCTGAACAT 
ATGCTGATGC GAGTGCCCCG GGATGGGGCC TTCCTGGTGC GGAAACGCAA TGAGCCTAAC 
TCATATGCCA TCTCTTTCCG GGCTGAGGGA AAGATCAAGC ACTGCCGAGT ACAGCAGGAA 
GGCCAGACAG TGATGCTGGG GAACTCTGAG TTTGACAGCC TGGTTGACCT CATCAGCTAC 
TATGAGAAGC ACCCCCTGTA CCGCAAAATG AAGCTACGCT ACCCCATCAA CGAGGAGGCA 
CTGGAGAAGA TCGGGACAGC TGAACCCGAT TATGGGGCAC TATACGAGGG CCGCAACCCT 
GGTTTCTATG TGGAGGCAAA CCCTATGCCA ACTTTCAAGT GTGCAGTAAA AGCCCTCTTC 
GACTACAAGG CCCAGAGAGA GGATGAGCTG ACCTTCACCA AGAGTGCCAT CATCCAGAAT 
GTGGAAAAGC AAGATGGTGG CTGGTGGCGA GGGGACTATG GTGGGAAGAA GCAGCTGTGG 
TTCCCCTCAA ACTATGTGGA AGAGATGATC AATCCAGCAG TCCTAGAGCC TGAGAGGGAG 
CACCTGGATG AGAACAGCCC ACTGGGGGAC TTGCTGCGAG GGGTCTTAGA TGTGCCAGCT 
TGTCAGATCG CCATCCGTCC TGAGGGCAAA AACAACCGGC TCTTCGTCTT CTCCATCAGC 
ATGCCATCAG TGGCTCAGTG GTCCCTGGAT GTTGCAGCTG ACTCACAGGA GGAGTTACAG 
GACTGGGTGA AAAAGATCCG TGAAGTTGCC CAGACTGCAG ATGCCAGGCT CACTGAGGGA 
AAGATGATGG AGAGGAGGAA GAAGATCGCC TTGGAGCTCT CCGAGCTTGT GGTCTACTGC 
CGGCCCGTTC CCTTTGATGA AGAGAAGATT GGCACAGAAC GTGCTTGTTA CCGGGACATG 
TCCTCCTTTC CGGAAACCAA GGCTGAGAAG TATGTGAACA AGGCCAAAGG CAAGAAGTTC 
CTCCAGTACA ACCGGCTGCA GCTCTCGCGC ATCTACCCTA AGGGCCAGAG GCTAGACTCC 
TCCAATTATG ACCCTCTGCC CATGTGGATC TGCGGTAGCC AGCTTGTAGC ACTCAATTTC 
CAGACCCCAG ACAAGCCTAT GCAGATGAAC CAGGCCCTCT TCATGGCTGG TGGGCATTGT 
GGCTATGTGC TGCAGCCAAG CACCATGAGA GACGAAGCCT TTGACCCCTT TGATAAGAGC 
AGTCTCCGAG GTCTGGAACC CTGTGTCATT TGCATTGAGG TGCTGGGGGC CAGGCATCTG 
CCGAAGAATG GCCGGGGTAT TGTGTGTCCT TTTGTGGAGA TTGAGGTGGC TGGGGCTGAG 
TACGACAGCA CCAAGCAAAA GACGGAGTTT GTAGTGGACA ACGGACTGAA CCCTGTGTGG 
CCTGCTAAGC CCTTCCACTT CCAGATCAGT AACCCAGAGT TTGCCTTTCT GCGCTTTGTG 
GTGTATGAGG AAGACATGTT TAGTGACCAG AACTTCTTGG CTCAGGCTAC TTTCCCAGTA 
AAAGGCCTGA AGACAGGATA TAGAGCAGTG CCTTTGAAGA ACAACTACAG TGAAGACCTG 
GAGTTGGCCT CCCTGCTCAT CAAGATTGAC ATTTTCCCTG CTAAGGAGAA CGGTGACCTC 
AGTCCTTTCA GTGGCATATC CCTAAGGGAA CGGGCCTCAG ATGCCTCCAG CCAGCTGTTC 
CATGTCCGGG CCCGGGAAGG GTCCTTTGAA GCCAGATACC AGCAGCCATT TGAAGATTTC 
CGCATCTCGC AGGAGCATCT AGCAGACCAT TTTGACAGTC GGGAACGAAG TACTTCAGAT 
GGTCCTTCCT CAGCCACTAA CCTTATTGAG GATCCCTTAC ATGACAAGCT GTGGAAGTGC 
TCTCTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate.
Journal of dental research22034517750141(2018 Jan)
Xu J,Huang Z,Wang W,Tan X,Li H,Zhang Y,Tian W,Hu T,Chen YP

Dysregulated PDGFR? signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification.
Development (Cambridge, England)144(21)4026-4036(2017 11)
He F,Soriano P

PLC?-dependent mTOR signalling controls IL-7-mediated early B cell development.
Nature communications8(1)1457(2017 Nov)
Yu M,Chen Y,Zeng H,Zheng Y,Fu G,Zhu W,Broeckel U,Aggarwal P,Turner A,Neale G,Guy C,Zhu N,Chi H,Wen R,Wang D

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Plcg1 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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