Scgb1a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Scgb1a1
Entrez Gene ID	25575
Full Name	secretoglobin family 1A member 1
Synonyms	CC10,CCSP,PCBB,Ugb
General protein information	Preferred Names secretoglobin family 1A member 1 Names uteroglobin CCPBP PCB-binding protein Uteroglobin (Clara cell secretory protein) clara cell phospholipid-binding protein clara cells 10 kDa secretory protein secretoglobin, family 1A, member 1 (uteroglobin)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43
Summary	binds polychlorinated biphenyls [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013051.1	NP_037183.1	uteroglobin precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Scgb1a1	NP_037183.1
Pan troglodytes (chimpanzee)	SCGB1A1	XP_001152343.1
Mus musculus (house mouse)	Scgb1a1	NP_035811.1
Homo sapiens (human)	SCGB1A1	NP_003348.1
	LOC718857	XP_001116505.1
Canis lupus familiaris (dog)	SCGB1A1	XP_005631683.1

Gene Ontology
Bibliography

Related articles in PubMed

Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection.
Fornander L, Ghafouri B, Kihlstr?m E, Akerlind B, Sch?n T, Tagesson C, Lindahl M
Proteomics. Clinical applications5(9-10)513-22(2011 Oct)

Role of distinct phospholipases A2 and their modulators in meconium aspiration syndrome in human neonates.
De Luca D, Minucci A, Tripodi D, Piastra M, Pietrini D, Zuppi C, Conti G, Carnielli VP, Capoluongo E
Intensive care medicine37(7)1158-65(2011 Jul)

Polydatin up-regulates Clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro.
Shiyu S, Zhiyu L, Mao Y, Lin B, Lijia W, Tianbao Z, Jie C, Tingyu L
BMC cell biology1231(2011 Jul)

The CC16 A38G polymorphism is associated with the development of asthma in children with allergic rhinitis.
Ku MS, Sun HL, Lu KH, Sheu JN, Lee HS, Yang SF, Lue KH
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology41(6)794-800(2011 Jun)

Use of serum clara cell 16-kDa (CC16) levels as a potential indicator of active pulmonary fibrosis in systemic sclerosis.
Hasegawa M, Fujimoto M, Hamaguchi Y, Matsushita T, Inoue K, Sato S, Takehara K
The Journal of rheumatology38(5)877-84(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Silica exposure causes dynamic changes of SP-D and CC16 protein expression in lung tissue and bronchoalveolar lavage fluid.
Title: [Dynamic changes of surfactant protein-D and Clara cell protein expressions in lung tissue and bronchoalveolar lavage fluid of silica-treated rats].

Results show that secretory markers such as CFTR, CC10, and CC26 are present in taste cells of rat circumvallate papillae, and their immunoreactivity is expressed, to a different extent, in subsets of taste cells that express alpha-gustducin.
Title: Immunohistochemical localization of cystic fibrosis transmembrane regulator and clara cell secretory protein in taste receptor cells of rat circumvallate papillae.

The expression level of CC16 in lung tissues and BALF decreased in rat lung tissues exposed to mixed air pollutants.
Title: [Effects of air mixed certain pollutants on the expression of CC16 and certain cytokine in pulmonary tissue of rats].

IL-13 induces CCSP expression via an EGFR- and leukocyte-dependent pathway.
Title: IL-13-induced Clara cell secretory protein expression in airway epithelium: role of EGFR signaling pathway.

The following Scgb1a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scgb1a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01786	NM_013051.1 Latest version!	Rattus norvegicus secretoglobin family 1A member 1 (Scgb1a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Scgb1a1 ( NM_013051.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037183.1 Rattus norvegicus secretoglobin family 1A member 1 (Scgb1a1), mRNA.

Price & Availability↑

CloneID	ORa01786
Clone ID Related Accession (Same CDS sequence)	NM_013051.1
Accession Version	NM_013051.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 291bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	uteroglobin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from J05536.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J05536.1, FQ151024.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689601 [ECO:0000348] ##Evidence-Data-END##

ATGAAGATCG CCATCACAAT CACTGTGCTC ATGCTGTCCA TCTGCTGCAG CTCAGCCTCT 
TCGGACATCT GCCCAGGATT TCTTCAAGTC CTTGAGGCCC TCCTCCTAGG CTCAGAGTCT 
AATTATGAGG CAGCCCTGAA GCCTTTCAAC CCTGCCTCAG ACCTGCAAAA TGCAGGAACC 
CAGCTGAAGA GGCTGGTGGA TACCCTCCCA CAGGAGACCA GAATAAACAT CGTGAAGCTC 
ACGGAGAAGA TCCTAACAAG TCCTCTGTGT GAGCAAGATT TAAGAGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037183.1
CDS	58..348
Translation	MKIAITITVLMLSICCSSASSDICPGFLQVLEALLLGSESNYEAALKPFNPASDLQNAGTQLKRLVDTLPQETRINIVKLTEKILTSPLCEQDLRV

Target ORF information:

RefSeq Version	NM_013051.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus secretoglobin family 1A member 1 (Scgb1a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013051.1

ORF Insert Sequence:

ATGAAGATCG CCATCACAAT CACTGTGCTC ATGCTGTCCA TCTGCTGCAG CTCAGCCTCT 
TCGGACATCT GCCCAGGATT TCTTCAAGTC CTTGAGGCCC TCCTCCTAGG CTCAGAGTCT 
AATTATGAGG CAGCCCTGAA GCCTTTCAAC CCTGCCTCAG ACCTGCAAAA TGCAGGAACC 
CAGCTGAAGA GGCTGGTGGA TACCCTCCCA CAGGAGACCA GAATAAACAT CGTGAAGCTC 
ACGGAGAAGA TCCTAACAAG TCCTCTGTGT GAGCAAGATT TAAGAGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection.
Proteomics. Clinical applications5(9-10)513-22(2011 Oct)
Fornander L,Ghafouri B,Kihlstr?m E,Akerlind B,Sch?n T,Tagesson C,Lindahl M

Role of distinct phospholipases A2 and their modulators in meconium aspiration syndrome in human neonates.
Intensive care medicine37(7)1158-65(2011 Jul)
De Luca D,Minucci A,Tripodi D,Piastra M,Pietrini D,Zuppi C,Conti G,Carnielli VP,Capoluongo E

Polydatin up-regulates Clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro.
BMC cell biology1231(2011 Jul)
Shiyu S,Zhiyu L,Mao Y,Lin B,Lijia W,Tianbao Z,Jie C,Tingyu L

The CC16 A38G polymorphism is associated with the development of asthma in children with allergic rhinitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology41(6)794-800(2011 Jun)
Ku MS,Sun HL,Lu KH,Sheu JN,Lee HS,Yang SF,Lue KH

Use of serum clara cell 16-kDa (CC16) levels as a potential indicator of active pulmonary fibrosis in systemic sclerosis.
The Journal of rheumatology38(5)877-84(2011 May)
Hasegawa M,Fujimoto M,Hamaguchi Y,Matsushita T,Inoue K,Sato S,Takehara K

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Scgb1a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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