Lgals4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lgals4
Entrez Gene ID	25474
Full Name	galectin 4
Synonyms	L-36,L36LBI
General protein information	Preferred Names galectin 4 Names galectin-4 L-36 lactose-binding protein L36LBP Lectin, galactose binding, soluble 4 (Galectin-4) gal-4 lactose-binding lectin 4 lectin, galactoside-binding, soluble, 4 (galectin 4)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	lactose-binding lectin [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_012975.1	NP_037107.1	galectin-4
XM_008759113.2	XP_008757335.1	galectin-4 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LGALS4	XP_512641.3
	LGALS4	XP_001084043.1
Mus musculus (house mouse)	Lgals4	NP_034836.1
Canis lupus familiaris (dog)	LGALS4	XP_003432633.1
Xenopus tropicalis (tropical clawed frog)	lgals4	NP_001011449.1
Homo sapiens (human)	LGALS4	NP_006140.1
Bos taurus (cattle)	LGALS4	NP_001029940.1
Rattus norvegicus (Norway rat)	Lgals4	NP_037107.1

Gene Ontology
Bibliography

Related articles in PubMed

Galectin-4 expression is down-regulated in response to autophagy during differentiation of rat trophoblast cells.
Arikawa T, Liao S, Shimada H, Inoue T, Sakata-Haga H, Nakamura T, Hatta T, Shoji H
Scientific reports632248(2016 Aug)

Neuronal Galectin-4 is required for axon growth and for the organization of axonal membrane L1 delivery and clustering.
Velasco S, D?ez-Revuelta N, Hern?ndez-Iglesias T, Kaltner H, Andr? S, Gabius HJ, Abad-Rodr?guez J
Journal of neurochemistry125(1)49-62(2013 Apr)

Expression pattern of Galectin 4 in rat placentation.
Arikawa T, Simamura E, Shimada H, Nishi N, Tatsuno T, Ishigaki Y, Tomosugi N, Yamashiro C, Hata T, Takegami T, Mogami H, Yamaguchi K, Nakamura T, Otani H, Hatta T, Shoji H
Placenta33(10)885-7(2012 Oct)

Galectin-4, a novel neuronal regulator of myelination.
Stancic M, Slijepcevic D, Nomden A, Vos MJ, de Jonge JC, Sikkema AH, Gabius HJ, Hoekstra D, Baron W
Glia60(6)919-35(2012 May)

Role of the carbohydrate recognition domains of mouse galectin-4 in oligosaccharide binding and epitope recognition and expression of galectin-4 and galectin-6 in mouse cells and tissues.
Markov? V, Smetana K Jr, Jen?kov? G, L?chov? J, Krejcir?kov? V, Poplstein M, F?bry M, Brynda J, Alvarez RA, Cummings RD, Maly P
International journal of molecular medicine18(1)65-76(2006 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Gal-4 sorts to axon plasma membrane segments by binding to sulfatide-containing microtubule-associated carriers and organizes the transport of L1, and likely other axonal glycoproteins, by attaching them to the carriers through their LacNAc termini.
Title: Neuronal Galectin-4 is required for axon growth and for the organization of axonal membrane L1 delivery and clustering.

In the rat placenta, immunohistochemical analysis showed that Gal4 is preferentially located in the maternal-fetal junctional zone. These results suggest that down-regulation of Gal4 may be involved in the promotion of trophoblast cell differentiation
Title: Expression pattern of Galectin 4 in rat placentation.

This study demonistrated that neuronal galectin-4 as a candidate for a soluble regulator of OLG differentiation and, hence, myelination.
Title: Galectin-4, a novel neuronal regulator of myelination.

The expression of galectin 4 was determined in the rat small intestine during postnatal development.
Title: Expression of galectin 4 in the rat small intestine during postnatal development.

The following Lgals4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lgals4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01529	NM_012975.1 Latest version!	Rattus norvegicus galectin 4 (Lgals4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa43121	XM_008759113.2 Latest version!	Rattus norvegicus galectin 4 (Lgals4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lgals4 ( NM_012975.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037107.1 Rattus norvegicus galectin 4 (Lgals4), mRNA.

Price & Availability↑

CloneID	ORa01529
Clone ID Related Accession (Same CDS sequence)	NM_012975.1
Accession Version	NM_012975.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	galectin-4
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M73553.1. ##Evidence-Data-START## Transcript exon combination :: M73553.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689603, SAMN02642794 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTATG TCCCAGCACC CGGCTACCAG CCCACCTACA ATCCGACGCT GCCCTACAAG 
AGGCCCATCC CAGGTGGCCT CAGTGTCGGA ATGTCCATTT ACATCCAAGG AATAGCCAAA 
GACAACATGA GACGGTTCCA CGTGAACTTT GCTGTGGGGC AGGATGAGGG GGCAGATATT 
GCTTTCCACT TCAACCCCCG GTTTGATGGC TGGGACAAGG TGGTCTTCAA TACGATGCAA 
AGCGGACAGT GGGGCAAGGA AGAGAAGAAG AAGAGCATGC CTTTCCAAAA GGGTCACCAC 
TTCGAGCTGG TGTTCATGGT CATGTCTGAG CACTACAAGG TCGTGGTAAA CGGAACTCCC 
TTCTACGAAT ATGGGCACCG GTTGCCCCTA CAGATGGTCA CCCACTTGCA AGTGGATGGG 
GACCTGGAAC TTCAGTCAAT CAACTTCCTT GGGGGCCAAC CTGCTGCATC CCAGTATCCG 
GGAACCATGA CTATTCCAGC TTATCCTAGT GCTGGGTACA ACCCTCCACA GATGAACAGC 
CTGCCTGTCA TGGCGGGACC CCCGATCTTC AATCCGCCTG TGCCATATGT GGGGACCCTG 
CAGGGGGGCC TTACAGCCCG AAGAACCATC ATAATCAAGG GATATGTACT TCCTACAGCC 
AAGAACCTTA TCATCAACTT CAAGGTGGGG TCGACCGGAG ACATAGCTTT TCACATGAAC 
CCCCGCATAG GTGATTGTGT GGTTCGCAAC AGCTATATGA ATGGCTCTTG GGGCTCCGAA 
GAGAGGAAGA TACCCTACAA CCCGTTTGGC GCTGGGCAGT TCTTTGATCT GTCAATCCGC 
TGCGGCACGG ATCGATTCAA GGTGTTTGCC AACGGCCAGC ACCTTTTCGA CTTCTCACAT 
CGGTTCCAAG CATTCCAAAG GGTAGACATG CTGGAGATCA AAGGCGACAT CACCTTGTCC 
TATGTCCAGA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037107.1
CDS	13..987
Translation	MAYVPAPGYQPTYNPTLPYKRPIPGGLSVGMSIYIQGIAKDNMRRFHVNFAVGQDEGADIAFHFNPRFDGWDKVVFNTMQSGQWGKEEKKKSMPFQKGHHFELVFMVMSEHYKVVVNGTPFYEYGHRLPLQMVTHLQVDGDLELQSINFLGGQPAASQYPGTMTIPAYPSAGYNPPQMNSLPVMAGPPIFNPPVPYVGTLQGGLTARRTIIIKGYVLPTAKNLIINFKVGSTGDIAFHMNPRIGDCVVRNSYMNGSWGSEERKIPYNPFGAGQFFDLSIRCGTDRFKVFANGQHLFDFSHRFQAFQRVDMLEIKGDITLSYVQI

Target ORF information:

RefSeq Version	NM_012975.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus galectin 4 (Lgals4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012975.1

ORF Insert Sequence:

ATGGCCTATG TCCCAGCACC CGGCTACCAG CCCACCTACA ATCCGACGCT GCCCTACAAG 
AGGCCCATCC CAGGTGGCCT CAGTGTCGGA ATGTCCATTT ACATCCAAGG AATAGCCAAA 
GACAACATGA GACGGTTCCA CGTGAACTTT GCTGTGGGGC AGGATGAGGG GGCAGATATT 
GCTTTCCACT TCAACCCCCG GTTTGATGGC TGGGACAAGG TGGTCTTCAA TACGATGCAA 
AGCGGACAGT GGGGCAAGGA AGAGAAGAAG AAGAGCATGC CTTTCCAAAA GGGTCACCAC 
TTCGAGCTGG TGTTCATGGT CATGTCTGAG CACTACAAGG TCGTGGTAAA CGGAACTCCC 
TTCTACGAAT ATGGGCACCG GTTGCCCCTA CAGATGGTCA CCCACTTGCA AGTGGATGGG 
GACCTGGAAC TTCAGTCAAT CAACTTCCTT GGGGGCCAAC CTGCTGCATC CCAGTATCCG 
GGAACCATGA CTATTCCAGC TTATCCTAGT GCTGGGTACA ACCCTCCACA GATGAACAGC 
CTGCCTGTCA TGGCGGGACC CCCGATCTTC AATCCGCCTG TGCCATATGT GGGGACCCTG 
CAGGGGGGCC TTACAGCCCG AAGAACCATC ATAATCAAGG GATATGTACT TCCTACAGCC 
AAGAACCTTA TCATCAACTT CAAGGTGGGG TCGACCGGAG ACATAGCTTT TCACATGAAC 
CCCCGCATAG GTGATTGTGT GGTTCGCAAC AGCTATATGA ATGGCTCTTG GGGCTCCGAA 
GAGAGGAAGA TACCCTACAA CCCGTTTGGC GCTGGGCAGT TCTTTGATCT GTCAATCCGC 
TGCGGCACGG ATCGATTCAA GGTGTTTGCC AACGGCCAGC ACCTTTTCGA CTTCTCACAT 
CGGTTCCAAG CATTCCAAAG GGTAGACATG CTGGAGATCA AAGGCGACAT CACCTTGTCC 
TATGTCCAGA TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lgals4 ( XM_008759113.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757335.1 Rattus norvegicus galectin 4 (Lgals4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa43121
Clone ID Related Accession (Same CDS sequence)	XM_008759113.2
Accession Version	XM_008759113.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	galectin-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008759113.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTATG TCCCAGCACC CGGCTACCAG CCCACCTACA ATCCGACGCT GCCCTACAAG 
AGGCCCATCC CAGGTGGCCT CAGTGTCGGA ATGTCCATTT ACATCCAAGG AATAGCCAAA 
GACAACATGA GACGGTTCCA CGTGAACTTT GCTGTGGGGC AGGATGAGGG GGCAGATATT 
GCTTTCCACT TCAACCCCCG GTTTGATGGC TGGGACAAGG TGGTCTTCAA TACGATGCAA 
AGCGGACAGT GGGGCAAGGA AGAGAAGAAG AAGAGCATGC CTTTCCAAAA GGGTCACCAC 
TTCGAGCTGG TGTTCATGGT CATGTCTGAG CACTACAAGG TCGTGGTAAA CGGAACTCCC 
TTCTACGAAT ATGGGCACCG GTTGCCCCTA CAGATGGTCA CCCACTTGCA AGTGGATGGG 
GACCTGGAAC TTCAGTCAAT CAACTTCCTT GGGGGCCAAC CTGCTGCATC CCAGTATCCG 
GGAACCATGA CTATTCCAGC TTATCCTAGT GCTGGGTACA ACCCTCCACA GATGAACAGC 
CTGCCTGTCA TGGCGGGACC CCCGATCTTC AATCCGCCTG TGCCATATGT GGGGACCCTG 
CAGGGGGGCC TTACAGCCCG AAGAACCATC ATAATCAAGG GATATGTACT TCCTACAGCC 
AAGAACCTTA TCATCAACTT CAAGGTGGGG TCGACCGGAG ACATAGCTTT TCACATGAAC 
CCCCGCATAG GTGATTGTGT GGTTCGCAAC AGCTATATGA ATGGCTCTTG GGGCTCCGAA 
GAGAGGAAGA TACCCTACAA CCCGTTTGGC GCTGGGCAGT TCTTTGATGT GAGTCTGGGG 
GTCCTCTTCT CGGTTCCCAC AAATCCCAGT CTGGCTGGAC CTCATCTTTC CTTTCCCCTA 
CAGCTGTCAA TCCGCTGCGG CACGGATCGA TTCAAGGTGT TTGCCAACGG CCAGCACCTT 
TTCGACTTCT CACATCGGTT CCAAGCATTC CAAAGGGTAG ACATGCTGGA GATCAAAGGC 
GACATCACCT TGTCCTATGT CCAGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757335.1
CDS	390..1439
Translation	MAYVPAPGYQPTYNPTLPYKRPIPGGLSVGMSIYIQGIAKDNMRRFHVNFAVGQDEGADIAFHFNPRFDGWDKVVFNTMQSGQWGKEEKKKSMPFQKGHHFELVFMVMSEHYKVVVNGTPFYEYGHRLPLQMVTHLQVDGDLELQSINFLGGQPAASQYPGTMTIPAYPSAGYNPPQMNSLPVMAGPPIFNPPVPYVGTLQGGLTARRTIIIKGYVLPTAKNLIINFKVGSTGDIAFHMNPRIGDCVVRNSYMNGSWGSEERKIPYNPFGAGQFFDVSLGVLFSVPTNPSLAGPHLSFPLQLSIRCGTDRFKVFANGQHLFDFSHRFQAFQRVDMLEIKGDITLSYVQI

Target ORF information:

RefSeq Version	XM_008759113.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus galectin 4 (Lgals4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759113.2

ORF Insert Sequence:

ATGGCCTATG TCCCAGCACC CGGCTACCAG CCCACCTACA ATCCGACGCT GCCCTACAAG 
AGGCCCATCC CAGGTGGCCT CAGTGTCGGA ATGTCCATTT ACATCCAAGG AATAGCCAAA 
GACAACATGA GACGGTTCCA CGTGAACTTT GCTGTGGGGC AGGATGAGGG GGCAGATATT 
GCTTTCCACT TCAACCCCCG GTTTGATGGC TGGGACAAGG TGGTCTTCAA TACGATGCAA 
AGCGGACAGT GGGGCAAGGA AGAGAAGAAG AAGAGCATGC CTTTCCAAAA GGGTCACCAC 
TTCGAGCTGG TGTTCATGGT CATGTCTGAG CACTACAAGG TCGTGGTAAA CGGAACTCCC 
TTCTACGAAT ATGGGCACCG GTTGCCCCTA CAGATGGTCA CCCACTTGCA AGTGGATGGG 
GACCTGGAAC TTCAGTCAAT CAACTTCCTT GGGGGCCAAC CTGCTGCATC CCAGTATCCG 
GGAACCATGA CTATTCCAGC TTATCCTAGT GCTGGGTACA ACCCTCCACA GATGAACAGC 
CTGCCTGTCA TGGCGGGACC CCCGATCTTC AATCCGCCTG TGCCATATGT GGGGACCCTG 
CAGGGGGGCC TTACAGCCCG AAGAACCATC ATAATCAAGG GATATGTACT TCCTACAGCC 
AAGAACCTTA TCATCAACTT CAAGGTGGGG TCGACCGGAG ACATAGCTTT TCACATGAAC 
CCCCGCATAG GTGATTGTGT GGTTCGCAAC AGCTATATGA ATGGCTCTTG GGGCTCCGAA 
GAGAGGAAGA TACCCTACAA CCCGTTTGGC GCTGGGCAGT TCTTTGATGT GAGTCTGGGG 
GTCCTCTTCT CGGTTCCCAC AAATCCCAGT CTGGCTGGAC CTCATCTTTC CTTTCCCCTA 
CAGCTGTCAA TCCGCTGCGG CACGGATCGA TTCAAGGTGT TTGCCAACGG CCAGCACCTT 
TTCGACTTCT CACATCGGTT CCAAGCATTC CAAAGGGTAG ACATGCTGGA GATCAAAGGC 
GACATCACCT TGTCCTATGT CCAGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Galectin-4 expression is down-regulated in response to autophagy during differentiation of rat trophoblast cells.
Scientific reports632248(2016 Aug)
Arikawa T,Liao S,Shimada H,Inoue T,Sakata-Haga H,Nakamura T,Hatta T,Shoji H

Neuronal Galectin-4 is required for axon growth and for the organization of axonal membrane L1 delivery and clustering.
Journal of neurochemistry125(1)49-62(2013 Apr)
Velasco S,D?ez-Revuelta N,Hern?ndez-Iglesias T,Kaltner H,Andr? S,Gabius HJ,Abad-Rodr?guez J

Expression pattern of Galectin 4 in rat placentation.
Placenta33(10)885-7(2012 Oct)
Arikawa T,Simamura E,Shimada H,Nishi N,Tatsuno T,Ishigaki Y,Tomosugi N,Yamashiro C,Hata T,Takegami T,Mogami H,Yamaguchi K,Nakamura T,Otani H,Hatta T,Shoji H

Galectin-4, a novel neuronal regulator of myelination.
Glia60(6)919-35(2012 May)
Stancic M,Slijepcevic D,Nomden A,Vos MJ,de Jonge JC,Sikkema AH,Gabius HJ,Hoekstra D,Baron W

Role of the carbohydrate recognition domains of mouse galectin-4 in oligosaccharide binding and epitope recognition and expression of galectin-4 and galectin-6 in mouse cells and tissues.
International journal of molecular medicine18(1)65-76(2006 Jul)
Markov? V,Smetana K Jr,Jen?kov? G,L?chov? J,Krejcir?kov? V,Poplstein M,F?bry M,Brynda J,Alvarez RA,Cummings RD,Maly P

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Lgals4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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