Mas1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mas1
Entrez Gene ID	25153
Full Name	MAS1 proto-oncogene, G protein-coupled receptor
Synonyms	Mgra,c-mas
General protein information	Preferred Names MAS1 proto-oncogene, G protein-coupled receptor Names proto-oncogene Mas MAS proto-oncogene MAS1 oncogene Mas-related G protein-coupled receptor a angiotensin-(1-7) receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q11
Summary	oncogene; may be involved in function or development of neural tissues [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017588808.1	XP_017444297.1	proto-oncogene Mas isoform X1
XM_017588807.1	XP_017444296.1	proto-oncogene Mas isoform X1
NM_012757.2	NP_036889.1	proto-oncogene Mas
XM_006227860.3	XP_006227922.1	proto-oncogene Mas isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	MAS1	NP_002368.1
Pan troglodytes (chimpanzee)	MAS1	XP_527553.1
Mus musculus (house mouse)	Mas1	NP_032578.2
Gallus gallus (chicken)	MAS1	XP_426151.2
Xenopus tropicalis (tropical clawed frog)	LOC100494761	XP_002938917.1
Xenopus tropicalis (tropical clawed frog)	LOC100492615	XP_002936478.1
	MAS1	XP_001098523.1
Rattus norvegicus (Norway rat)	Mas1	NP_036889.1
Xenopus tropicalis (tropical clawed frog)	LOC100492282	XP_002936476.1
Canis lupus familiaris (dog)	MAS1	XP_005615616.1
Bos taurus (cattle)	MAS1	XP_002690422.1
Xenopus tropicalis (tropical clawed frog)	LOC100492446	XP_002936477.1

Gene Ontology
Bibliography

Related articles in PubMed

Intrarenal Mas and AT
O'Neill J, Healy V, Johns EJ
Experimental physiology102(12)1700-1715(2017 Dec)

The ACE2-Ang?(1-7)-Mas receptor axis attenuates cardiac remodeling and fibrosis in post-myocardial infarction.
Wang J, He W, Guo L, Zhang Y, Li H, Han S, Shen D
Molecular medicine reports16(2)1973-1981(2017 Aug)

Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium.
Hoffmann BR, Stodola TJ, Wagner JR, Didier DN, Exner EC, Lombard JH, Greene AS
Arteriosclerosis, thrombosis, and vascular biology37(3)433-445(2017 Mar)

Effects of Diabetic Hyperglycemia on Central Ang-(1-7)-Mas-R-nNOS Pathways in Spontaneously Hypertensive Rats.
Li H, Liu X, Ren Z, Gu J, Lu Y, Wang X, Zhang L
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology40(5)1186-1197(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

AngII/AT1R and Ang-(1-7)/Mas1 receptor signaling converge on anessential common pathway of importance for both angiogenesis and vasodilation in the renin-angiotensin system involving ERK1/2 and p38MAPK signaling.
Title: Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium.

Ang-(1-5) is an active mediator of renin-angiotensin system to stimulate ANP secretion via Mas R and PI3K-Akt-NOS pathway.
Title: Angiotensin-(1-5), an active mediator of renin-angiotensin system, stimulates ANP secretion via Mas receptor.

Mas receptor antagonist abolished relaxation while bradykinin receptor antagonist only slightly reduced it, suggesting that bradykinin-induced vasorelaxation is regulated also by other mechanisms than the classical BR1/BR2 pathway.
Title: Bradykinin -induced vasodilatation: Role of age, ACE1-inhibitory peptide, mas- and bradykinin receptors.

valsartan attenuates neointimal hyperplasiain balloon-injured rat aortic arteries through activation of the ACE2-angiotensin-(1-7)-Mas axis as well as inhibition of the ACE-angiotensin II-AT1 and p-ERK pathways.
Title: Valsartan attenuates intimal hyperplasia in balloon-injured rat aortic arteries through modulating the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis.

enhancing Ang-(1-7)-Mas-R-nNOS system is likely to be beneficial in preventing against cardiovascular and cerebrovascular dysfunction.
Title: Effects of Diabetic Hyperglycemia on Central Ang-(1-7)-Mas-R-nNOS Pathways in Spontaneously Hypertensive Rats.

The following Mas1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mas1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12587	NM_012757.2 Latest version!	Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa12587	XM_017588808.1 Latest version!	Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa12587	XM_017588807.1 Latest version!	Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa12587	XM_006227860.3 Latest version!	Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mas1 ( NM_012757.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_036889.1 Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), mRNA.

Price & Availability↑

CloneID	ORa12587
Clone ID Related Accession (Same CDS sequence)	XM_017588808.1 , XM_017588807.1 , NM_012757.2 , XM_006227860.3
Accession Version	NM_012757.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	proto-oncogene Mas
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC078884.1. On Aug 23, 2004 this sequence version replaced NM_012757.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC078884.1, CK599058.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689595, SAMEA2689604 [ECO:0000350] ##Evidence-Data-END##

ATGGACCAAT CAAATATGAC ATCCTTTGCT GAGGAGAAAG CCATGAATAC CTCCAGCAGA 
AATGCCTCCC TGGGGACTTC ACACCCACCC ATTCCCATAG TGCACTGGGT CATCATGAGC 
ATCTCTCCTC TCGGCTTTGT GGAGAACGGG ATCCTCCTCT GGTTCCTTTG CTTCCGGATG 
AGGAGAAATC CCTTCACGGT CTATATCACC CACTTGTCCA TTGCTGACAT CTCCCTCCTG 
TTCTGTATTT TTATTCTGTC CATCGACTAT GCTTTAGACT ATGAACTCTC TTCTGGCCAT 
TACTACACAA TCGTGACGTT ATCGGTGACT TTTCTATTTG GCTACAACAC AGGCCTCTAT 
CTGCTGACAG CCATCAGTGT GGAGAGATGC CTTTCAGTCC TCTACCCCAT CTGGTACAGA 
TGTCACCGCC CCAAGCACCA GTCGGCATTC GTCTGTGCCC TCCTGTGGGC ACTTTCATGC 
TTGGTGACCA CCATGGAGTA CGTCATGTGT ATTGACAGCG GAGAAGAGAG TCACTCTCAG 
AGTGACTGTC GGGCGGTCAT CATCTTCATA GCCATCCTCA GCTTCTTGGT CTTCACTCCG 
CTCATGTTAG TGTCCAGCAC CATCTTGGTG GTGAAGATAC GGAAGAACAC ATGGGCCTCC 
CATTCTTCGA AGCTGTACAT CGTCATCATG GTCACCATTA TCATATTCCT CATCTTTGCC 
ATGCCCATGC GGGTCCTCTA CCTGTTGTAT TACGAGTACT GGTCAACCTT TGGGAACCTG 
CATAACATCT CCTTGCTTTT CTCCACCATC AATAGCAGCG CCAACCCTTT CATCTACTTT 
TTTGTGGGCA GCAGTAAGAA GAAGCGCTTC AGGGAGTCCT TAAAAGTGGT CCTGACCAGA 
GCTTTCAAAG ACGAGATGCA ACCTAGGCGT CAGGAGGGCA ATGGCAACAC TGTATCCATT 
GAGACTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036889.1
CDS	515..1489
Translation	MDQSNMTSFAEEKAMNTSSRNASLGTSHPPIPIVHWVIMSISPLGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKHQSAFVCALLWALSCLVTTMEYVMCIDSGEESHSQSDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRVLYLLYYEYWSTFGNLHNISLLFSTINSSANPFIYFFVGSSKKKRFRESLKVVLTRAFKDEMQPRRQEGNGNTVSIETVV

Target ORF information:

RefSeq Version	NM_012757.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012757.2

ORF Insert Sequence:

ATGGACCAAT CAAATATGAC ATCCTTTGCT GAGGAGAAAG CCATGAATAC CTCCAGCAGA 
AATGCCTCCC TGGGGACTTC ACACCCACCC ATTCCCATAG TGCACTGGGT CATCATGAGC 
ATCTCTCCTC TCGGCTTTGT GGAGAACGGG ATCCTCCTCT GGTTCCTTTG CTTCCGGATG 
AGGAGAAATC CCTTCACGGT CTATATCACC CACTTGTCCA TTGCTGACAT CTCCCTCCTG 
TTCTGTATTT TTATTCTGTC CATCGACTAT GCTTTAGACT ATGAACTCTC TTCTGGCCAT 
TACTACACAA TCGTGACGTT ATCGGTGACT TTTCTATTTG GCTACAACAC AGGCCTCTAT 
CTGCTGACAG CCATCAGTGT GGAGAGATGC CTTTCAGTCC TCTACCCCAT CTGGTACAGA 
TGTCACCGCC CCAAGCACCA GTCGGCATTC GTCTGTGCCC TCCTGTGGGC ACTTTCATGC 
TTGGTGACCA CCATGGAGTA CGTCATGTGT ATTGACAGCG GAGAAGAGAG TCACTCTCAG 
AGTGACTGTC GGGCGGTCAT CATCTTCATA GCCATCCTCA GCTTCTTGGT CTTCACTCCG 
CTCATGTTAG TGTCCAGCAC CATCTTGGTG GTGAAGATAC GGAAGAACAC ATGGGCCTCC 
CATTCTTCGA AGCTGTACAT CGTCATCATG GTCACCATTA TCATATTCCT CATCTTTGCC 
ATGCCCATGC GGGTCCTCTA CCTGTTGTAT TACGAGTACT GGTCAACCTT TGGGAACCTG 
CATAACATCT CCTTGCTTTT CTCCACCATC AATAGCAGCG CCAACCCTTT CATCTACTTT 
TTTGTGGGCA GCAGTAAGAA GAAGCGCTTC AGGGAGTCCT TAAAAGTGGT CCTGACCAGA 
GCTTTCAAAG ACGAGATGCA ACCTAGGCGT CAGGAGGGCA ATGGCAACAC TGTATCCATT 
GAGACTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mas1 ( XM_017588808.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444297.1 Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa12587
Clone ID Related Accession (Same CDS sequence)	XM_017588808.1 , XM_017588807.1 , NM_012757.2 , XM_006227860.3
Accession Version	XM_017588808.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	proto-oncogene Mas isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAAT CAAATATGAC ATCCTTTGCT GAGGAGAAAG CCATGAATAC CTCCAGCAGA 
AATGCCTCCC TGGGGACTTC ACACCCACCC ATTCCCATAG TGCACTGGGT CATCATGAGC 
ATCTCTCCTC TCGGCTTTGT GGAGAACGGG ATCCTCCTCT GGTTCCTTTG CTTCCGGATG 
AGGAGAAATC CCTTCACGGT CTATATCACC CACTTGTCCA TTGCTGACAT CTCCCTCCTG 
TTCTGTATTT TTATTCTGTC CATCGACTAT GCTTTAGACT ATGAACTCTC TTCTGGCCAT 
TACTACACAA TCGTGACGTT ATCGGTGACT TTTCTATTTG GCTACAACAC AGGCCTCTAT 
CTGCTGACAG CCATCAGTGT GGAGAGATGC CTTTCAGTCC TCTACCCCAT CTGGTACAGA 
TGTCACCGCC CCAAGCACCA GTCGGCATTC GTCTGTGCCC TCCTGTGGGC ACTTTCATGC 
TTGGTGACCA CCATGGAGTA CGTCATGTGT ATTGACAGCG GAGAAGAGAG TCACTCTCAG 
AGTGACTGTC GGGCGGTCAT CATCTTCATA GCCATCCTCA GCTTCTTGGT CTTCACTCCG 
CTCATGTTAG TGTCCAGCAC CATCTTGGTG GTGAAGATAC GGAAGAACAC ATGGGCCTCC 
CATTCTTCGA AGCTGTACAT CGTCATCATG GTCACCATTA TCATATTCCT CATCTTTGCC 
ATGCCCATGC GGGTCCTCTA CCTGTTGTAT TACGAGTACT GGTCAACCTT TGGGAACCTG 
CATAACATCT CCTTGCTTTT CTCCACCATC AATAGCAGCG CCAACCCTTT CATCTACTTT 
TTTGTGGGCA GCAGTAAGAA GAAGCGCTTC AGGGAGTCCT TAAAAGTGGT CCTGACCAGA 
GCTTTCAAAG ACGAGATGCA ACCTAGGCGT CAGGAGGGCA ATGGCAACAC TGTATCCATT 
GAGACTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444297.1
CDS	1591..2565
Translation	MDQSNMTSFAEEKAMNTSSRNASLGTSHPPIPIVHWVIMSISPLGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKHQSAFVCALLWALSCLVTTMEYVMCIDSGEESHSQSDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRVLYLLYYEYWSTFGNLHNISLLFSTINSSANPFIYFFVGSSKKKRFRESLKVVLTRAFKDEMQPRRQEGNGNTVSIETVV

Target ORF information:

RefSeq Version	XM_017588808.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588808.1

ORF Insert Sequence:

ATGGACCAAT CAAATATGAC ATCCTTTGCT GAGGAGAAAG CCATGAATAC CTCCAGCAGA 
AATGCCTCCC TGGGGACTTC ACACCCACCC ATTCCCATAG TGCACTGGGT CATCATGAGC 
ATCTCTCCTC TCGGCTTTGT GGAGAACGGG ATCCTCCTCT GGTTCCTTTG CTTCCGGATG 
AGGAGAAATC CCTTCACGGT CTATATCACC CACTTGTCCA TTGCTGACAT CTCCCTCCTG 
TTCTGTATTT TTATTCTGTC CATCGACTAT GCTTTAGACT ATGAACTCTC TTCTGGCCAT 
TACTACACAA TCGTGACGTT ATCGGTGACT TTTCTATTTG GCTACAACAC AGGCCTCTAT 
CTGCTGACAG CCATCAGTGT GGAGAGATGC CTTTCAGTCC TCTACCCCAT CTGGTACAGA 
TGTCACCGCC CCAAGCACCA GTCGGCATTC GTCTGTGCCC TCCTGTGGGC ACTTTCATGC 
TTGGTGACCA CCATGGAGTA CGTCATGTGT ATTGACAGCG GAGAAGAGAG TCACTCTCAG 
AGTGACTGTC GGGCGGTCAT CATCTTCATA GCCATCCTCA GCTTCTTGGT CTTCACTCCG 
CTCATGTTAG TGTCCAGCAC CATCTTGGTG GTGAAGATAC GGAAGAACAC ATGGGCCTCC 
CATTCTTCGA AGCTGTACAT CGTCATCATG GTCACCATTA TCATATTCCT CATCTTTGCC 
ATGCCCATGC GGGTCCTCTA CCTGTTGTAT TACGAGTACT GGTCAACCTT TGGGAACCTG 
CATAACATCT CCTTGCTTTT CTCCACCATC AATAGCAGCG CCAACCCTTT CATCTACTTT 
TTTGTGGGCA GCAGTAAGAA GAAGCGCTTC AGGGAGTCCT TAAAAGTGGT CCTGACCAGA 
GCTTTCAAAG ACGAGATGCA ACCTAGGCGT CAGGAGGGCA ATGGCAACAC TGTATCCATT 
GAGACTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mas1 ( XM_017588807.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444296.1 Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa12587
Clone ID Related Accession (Same CDS sequence)	XM_017588808.1 , XM_017588807.1 , NM_012757.2 , XM_006227860.3
Accession Version	XM_017588807.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	proto-oncogene Mas isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAAT CAAATATGAC ATCCTTTGCT GAGGAGAAAG CCATGAATAC CTCCAGCAGA 
AATGCCTCCC TGGGGACTTC ACACCCACCC ATTCCCATAG TGCACTGGGT CATCATGAGC 
ATCTCTCCTC TCGGCTTTGT GGAGAACGGG ATCCTCCTCT GGTTCCTTTG CTTCCGGATG 
AGGAGAAATC CCTTCACGGT CTATATCACC CACTTGTCCA TTGCTGACAT CTCCCTCCTG 
TTCTGTATTT TTATTCTGTC CATCGACTAT GCTTTAGACT ATGAACTCTC TTCTGGCCAT 
TACTACACAA TCGTGACGTT ATCGGTGACT TTTCTATTTG GCTACAACAC AGGCCTCTAT 
CTGCTGACAG CCATCAGTGT GGAGAGATGC CTTTCAGTCC TCTACCCCAT CTGGTACAGA 
TGTCACCGCC CCAAGCACCA GTCGGCATTC GTCTGTGCCC TCCTGTGGGC ACTTTCATGC 
TTGGTGACCA CCATGGAGTA CGTCATGTGT ATTGACAGCG GAGAAGAGAG TCACTCTCAG 
AGTGACTGTC GGGCGGTCAT CATCTTCATA GCCATCCTCA GCTTCTTGGT CTTCACTCCG 
CTCATGTTAG TGTCCAGCAC CATCTTGGTG GTGAAGATAC GGAAGAACAC ATGGGCCTCC 
CATTCTTCGA AGCTGTACAT CGTCATCATG GTCACCATTA TCATATTCCT CATCTTTGCC 
ATGCCCATGC GGGTCCTCTA CCTGTTGTAT TACGAGTACT GGTCAACCTT TGGGAACCTG 
CATAACATCT CCTTGCTTTT CTCCACCATC AATAGCAGCG CCAACCCTTT CATCTACTTT 
TTTGTGGGCA GCAGTAAGAA GAAGCGCTTC AGGGAGTCCT TAAAAGTGGT CCTGACCAGA 
GCTTTCAAAG ACGAGATGCA ACCTAGGCGT CAGGAGGGCA ATGGCAACAC TGTATCCATT 
GAGACTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444296.1
CDS	3745..4719
Translation	MDQSNMTSFAEEKAMNTSSRNASLGTSHPPIPIVHWVIMSISPLGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKHQSAFVCALLWALSCLVTTMEYVMCIDSGEESHSQSDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRVLYLLYYEYWSTFGNLHNISLLFSTINSSANPFIYFFVGSSKKKRFRESLKVVLTRAFKDEMQPRRQEGNGNTVSIETVV

Target ORF information:

RefSeq Version	XM_017588807.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017588807.1

ORF Insert Sequence:

ATGGACCAAT CAAATATGAC ATCCTTTGCT GAGGAGAAAG CCATGAATAC CTCCAGCAGA 
AATGCCTCCC TGGGGACTTC ACACCCACCC ATTCCCATAG TGCACTGGGT CATCATGAGC 
ATCTCTCCTC TCGGCTTTGT GGAGAACGGG ATCCTCCTCT GGTTCCTTTG CTTCCGGATG 
AGGAGAAATC CCTTCACGGT CTATATCACC CACTTGTCCA TTGCTGACAT CTCCCTCCTG 
TTCTGTATTT TTATTCTGTC CATCGACTAT GCTTTAGACT ATGAACTCTC TTCTGGCCAT 
TACTACACAA TCGTGACGTT ATCGGTGACT TTTCTATTTG GCTACAACAC AGGCCTCTAT 
CTGCTGACAG CCATCAGTGT GGAGAGATGC CTTTCAGTCC TCTACCCCAT CTGGTACAGA 
TGTCACCGCC CCAAGCACCA GTCGGCATTC GTCTGTGCCC TCCTGTGGGC ACTTTCATGC 
TTGGTGACCA CCATGGAGTA CGTCATGTGT ATTGACAGCG GAGAAGAGAG TCACTCTCAG 
AGTGACTGTC GGGCGGTCAT CATCTTCATA GCCATCCTCA GCTTCTTGGT CTTCACTCCG 
CTCATGTTAG TGTCCAGCAC CATCTTGGTG GTGAAGATAC GGAAGAACAC ATGGGCCTCC 
CATTCTTCGA AGCTGTACAT CGTCATCATG GTCACCATTA TCATATTCCT CATCTTTGCC 
ATGCCCATGC GGGTCCTCTA CCTGTTGTAT TACGAGTACT GGTCAACCTT TGGGAACCTG 
CATAACATCT CCTTGCTTTT CTCCACCATC AATAGCAGCG CCAACCCTTT CATCTACTTT 
TTTGTGGGCA GCAGTAAGAA GAAGCGCTTC AGGGAGTCCT TAAAAGTGGT CCTGACCAGA 
GCTTTCAAAG ACGAGATGCA ACCTAGGCGT CAGGAGGGCA ATGGCAACAC TGTATCCATT 
GAGACTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mas1 ( XM_006227860.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006227922.1 Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa12587
Clone ID Related Accession (Same CDS sequence)	XM_017588808.1 , XM_017588807.1 , NM_012757.2 , XM_006227860.3
Accession Version	XM_006227860.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	proto-oncogene Mas isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006227860.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAAT CAAATATGAC ATCCTTTGCT GAGGAGAAAG CCATGAATAC CTCCAGCAGA 
AATGCCTCCC TGGGGACTTC ACACCCACCC ATTCCCATAG TGCACTGGGT CATCATGAGC 
ATCTCTCCTC TCGGCTTTGT GGAGAACGGG ATCCTCCTCT GGTTCCTTTG CTTCCGGATG 
AGGAGAAATC CCTTCACGGT CTATATCACC CACTTGTCCA TTGCTGACAT CTCCCTCCTG 
TTCTGTATTT TTATTCTGTC CATCGACTAT GCTTTAGACT ATGAACTCTC TTCTGGCCAT 
TACTACACAA TCGTGACGTT ATCGGTGACT TTTCTATTTG GCTACAACAC AGGCCTCTAT 
CTGCTGACAG CCATCAGTGT GGAGAGATGC CTTTCAGTCC TCTACCCCAT CTGGTACAGA 
TGTCACCGCC CCAAGCACCA GTCGGCATTC GTCTGTGCCC TCCTGTGGGC ACTTTCATGC 
TTGGTGACCA CCATGGAGTA CGTCATGTGT ATTGACAGCG GAGAAGAGAG TCACTCTCAG 
AGTGACTGTC GGGCGGTCAT CATCTTCATA GCCATCCTCA GCTTCTTGGT CTTCACTCCG 
CTCATGTTAG TGTCCAGCAC CATCTTGGTG GTGAAGATAC GGAAGAACAC ATGGGCCTCC 
CATTCTTCGA AGCTGTACAT CGTCATCATG GTCACCATTA TCATATTCCT CATCTTTGCC 
ATGCCCATGC GGGTCCTCTA CCTGTTGTAT TACGAGTACT GGTCAACCTT TGGGAACCTG 
CATAACATCT CCTTGCTTTT CTCCACCATC AATAGCAGCG CCAACCCTTT CATCTACTTT 
TTTGTGGGCA GCAGTAAGAA GAAGCGCTTC AGGGAGTCCT TAAAAGTGGT CCTGACCAGA 
GCTTTCAAAG ACGAGATGCA ACCTAGGCGT CAGGAGGGCA ATGGCAACAC TGTATCCATT 
GAGACTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006227922.1
CDS	4452..5426
Translation	MDQSNMTSFAEEKAMNTSSRNASLGTSHPPIPIVHWVIMSISPLGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKHQSAFVCALLWALSCLVTTMEYVMCIDSGEESHSQSDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRVLYLLYYEYWSTFGNLHNISLLFSTINSSANPFIYFFVGSSKKKRFRESLKVVLTRAFKDEMQPRRQEGNGNTVSIETVV

Target ORF information:

RefSeq Version	XM_006227860.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MAS1 proto-oncogene, G protein-coupled receptor (Mas1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006227860.3

ORF Insert Sequence:

ATGGACCAAT CAAATATGAC ATCCTTTGCT GAGGAGAAAG CCATGAATAC CTCCAGCAGA 
AATGCCTCCC TGGGGACTTC ACACCCACCC ATTCCCATAG TGCACTGGGT CATCATGAGC 
ATCTCTCCTC TCGGCTTTGT GGAGAACGGG ATCCTCCTCT GGTTCCTTTG CTTCCGGATG 
AGGAGAAATC CCTTCACGGT CTATATCACC CACTTGTCCA TTGCTGACAT CTCCCTCCTG 
TTCTGTATTT TTATTCTGTC CATCGACTAT GCTTTAGACT ATGAACTCTC TTCTGGCCAT 
TACTACACAA TCGTGACGTT ATCGGTGACT TTTCTATTTG GCTACAACAC AGGCCTCTAT 
CTGCTGACAG CCATCAGTGT GGAGAGATGC CTTTCAGTCC TCTACCCCAT CTGGTACAGA 
TGTCACCGCC CCAAGCACCA GTCGGCATTC GTCTGTGCCC TCCTGTGGGC ACTTTCATGC 
TTGGTGACCA CCATGGAGTA CGTCATGTGT ATTGACAGCG GAGAAGAGAG TCACTCTCAG 
AGTGACTGTC GGGCGGTCAT CATCTTCATA GCCATCCTCA GCTTCTTGGT CTTCACTCCG 
CTCATGTTAG TGTCCAGCAC CATCTTGGTG GTGAAGATAC GGAAGAACAC ATGGGCCTCC 
CATTCTTCGA AGCTGTACAT CGTCATCATG GTCACCATTA TCATATTCCT CATCTTTGCC 
ATGCCCATGC GGGTCCTCTA CCTGTTGTAT TACGAGTACT GGTCAACCTT TGGGAACCTG 
CATAACATCT CCTTGCTTTT CTCCACCATC AATAGCAGCG CCAACCCTTT CATCTACTTT 
TTTGTGGGCA GCAGTAAGAA GAAGCGCTTC AGGGAGTCCT TAAAAGTGGT CCTGACCAGA 
GCTTTCAAAG ACGAGATGCA ACCTAGGCGT CAGGAGGGCA ATGGCAACAC TGTATCCATT 
GAGACTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Intrarenal Mas and AT
Experimental physiology102(12)1700-1715(2017 Dec)
O'Neill J,Healy V,Johns EJ

The ACE2-Ang?(1-7)-Mas receptor axis attenuates cardiac remodeling and fibrosis in post-myocardial infarction.
Molecular medicine reports16(2)1973-1981(2017 Aug)
Wang J,He W,Guo L,Zhang Y,Li H,Han S,Shen D

Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium.
Arteriosclerosis, thrombosis, and vascular biology37(3)433-445(2017 Mar)
Hoffmann BR,Stodola TJ,Wagner JR,Didier DN,Exner EC,Lombard JH,Greene AS

Effects of Diabetic Hyperglycemia on Central Ang-(1-7)-Mas-R-nNOS Pathways in Spontaneously Hypertensive Rats.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology40(5)1186-1197(2016)
Li H,Liu X,Ren Z,Gu J,Lu Y,Wang X,Zhang L

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Mas1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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