F9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	F9
Entrez Gene ID	24946
Full Name	coagulation factor IX
General protein information	Preferred Names coagulation factor IX Names coagulation factor IX Coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) christmas factor coagulation factor 9
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq36
Summary	may act as a blood coagulation protease [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017601915.1	XP_017457404.1	coagulation factor IX isoform X1
NM_031540.1	NP_113728.1	coagulation factor IX precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	F9	NP_032005.1
Rattus norvegicus (Norway rat)	F9	NP_113728.1
	F9	NP_001103153.1
Gallus gallus (chicken)	F9	NP_989674.1
Danio rerio (zebrafish)	f9b	NP_001035400.1
Danio rerio (zebrafish)	f9a	NP_878288.1
Xenopus tropicalis (tropical clawed frog)	f9	NP_001011223.1
Homo sapiens (human)	F9	NP_000124.1
Pan troglodytes (chimpanzee)	F9	NP_001129063.1
Canis lupus familiaris (dog)	F9	NP_001003323.1

Gene Ontology
Bibliography

Related articles in PubMed

Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability.
Metzger JM, Tadin-Strapps M, Thankappan A, Strapps WR, DiPietro M, Leander K, Zhang Z, Shin MK, Levorse J, Desai K, Xu Y, Lai K, Wu W, Chen Z, Cai TQ, Jochnowitz N, Bentley R, Hoos L, Zhou Y, Sepp-Lorenzino L, Seiffert D, Andre P
Thrombosis and haemostasis113(6)1300-11(2015 Jun)

How it all starts: Initiation of the clotting cascade.
Smith SA, Travers RJ, Morrissey JH
Critical reviews in biochemistry and molecular biology50(4)326-36(2015)

Nitrophorin 2, a factor IX(a)-directed anticoagulant, inhibits arterial thrombosis without impairing haemostasis.
Mizurini DM, Francischetti IM, Andersen JF, Monteiro RQ
Thrombosis and haemostasis104(6)1116-23(2010 Dec)

[Human coagulation factor IX gene therapy in murine hemophilia B by hydrodynamic delivery and site-specific genomic integration].
Zhang L, Gu DS, DU WT, Liu PX, Lu SH, Yang RC
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi31(5)294-9(2010 May)

Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice.
Verma D, Moghimi B, LoDuca PA, Singh HD, Hoffman BE, Herzog RW, Daniell H
Proceedings of the National Academy of Sciences of the United States of America107(15)7101-6(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data provide substantial evidence of a participation of fIX in the mechanisms regulating thrombosis prior to those regulating primary haemostasis.
Title: Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability.

Nitrophorin 2, a factor IX(a)-directed anticoagulant, is a potent and long-lasting inhibitor of arterial thrombosis with minor effects on haemostasis.
Title: Nitrophorin 2, a factor IX(a)-directed anticoagulant, inhibits arterial thrombosis without impairing haemostasis.

The following F9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the F9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa08035	NM_031540.1 Latest version!	Rattus norvegicus coagulation factor IX (F9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa63008	XM_017601915.1 Latest version!	Rattus norvegicus coagulation factor IX (F9), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

F9 ( NM_031540.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113728.1 Rattus norvegicus coagulation factor IX (F9), mRNA.

Price & Availability↑

CloneID	ORa08035
Clone ID Related Accession (Same CDS sequence)	NM_031540.1
Accession Version	NM_031540.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	coagulation factor IX precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07041911.1, FM036569.1, M26247.1 and AABR07041914.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689598, SAMN01906348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGACG CTCCGGGTCT CATCCCCATC TTCCTTCTGG GCTATCTACT CAGCACTGAA 
TGTGCAGTTT TTCTTGATCG CGAAAATGCC ACCAAAATTC TTACCCGTCC AAAGAGATAT 
AACTCAGGGA AACTGGAAGA GTTTGTTCAG GGAAACCTTG AGAGAGAGTG CATAGAAGAA 
AGATGCAGTT TTGAAGAAGC ACGAGAAGTT TTTGAAAACA CTGAAAAAAC TACTGAATTT 
TGGAAGCAGT ATGTTGATGG AGATCAGTGT GAATCAAATC CTTGCTTAAA TGGTGGAATA 
TGCAAGGATG ATATTAATTC CTATGAATGT TGGTGCCAAG CTGGATTTGA AGGAAGGAAC 
TGTGAATTAG ATGCAACATG TAGCATTAAA AATGGCAGGT GTAAGCAGTT TTGTAAAAAC 
AGCCCTGATA ACAAGATAAT TTGTTCCTGC ACTGAGGGAT ACCAACTTGC AGAAGACCAG 
AAGTCCTGTG AACCAGCAGT TCCATTCCCA TGTGGAAGAG TTTCTGTTGC CTACAATTCT 
AAAAAGATCA CCCGTGCTGA GACTGTTTTT TCTAATACCG ACTATGGAAA TTCCACTGAA 
TTAATCCTGG ATGACATCAC CAACAGCACC ATTCTTGATA ACCTCACTGA AAATAGTGAA 
CCAATTAATG ACTTCACTCG AGTTGTTGGT GGAGAAAATG CGAAACCAGG TCAAATCCCT 
TGGCAGGTCA TTCTAAATGG TGAAATTGAG GCATTCTGTG GAGGCGCCAT CATTAATGAA 
AAATGGATTG TAACTGCTGC CCACTGTCTT AAACCTGGTG ATAAAATTGA GGTTGTTGCT 
GGTGAACATA ATATTGATGA GAAGGAAGAC ACAGAACAAA GGAGAAATGT GATTCGAACT 
ATCCCTCATC ACCAGTACAA TGCAACTATT AATAAGTATA GTCATGACAT TGCCTTGCTG 
GAACTGGATA AACCTTTAAT ACTAAACAGC TATGTAACAC CTATCTGTGT TGCCAATAAG 
GAATATACAA ATATCTTCCT CAAGTTTGGT TCTGGTTATG TGAGTGGCTG GGGGAAAGTC 
TTCAACAAAG GGAGACAGGC TTCCATTCTT CAGTACCTTA GAGTTCCACT GGTTGACCGA 
GCCACATGCC TTAGGTCCAC AAAATTCAGC ATCTATAACA ACATGTTCTG TGCAGGTTAC 
CGTGAAGGAG GCAAAGATTC ATGTGAAGGA GATAGTGGGG GACCCCATGT TACTGAAGTA 
GAAGGGACAA GTTTCTTAAC TGGCATTATT AGCTGGGGTG AAGAATGTGC AATGAAAGGC 
AAATATGGAA TATATACTAA GGTTTCCAGG TATGTCAACT GGATTAAGGA AAAAACAAAG 
CTAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113728.1
CDS	1..1389
Translation	MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT

Target ORF information:

RefSeq Version	NM_031540.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus coagulation factor IX (F9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031540.1

ORF Insert Sequence:

ATGGCAGACG CTCCGGGTCT CATCCCCATC TTCCTTCTGG GCTATCTACT CAGCACTGAA 
TGTGCAGTTT TTCTTGATCG CGAAAATGCC ACCAAAATTC TTACCCGTCC AAAGAGATAT 
AACTCAGGGA AACTGGAAGA GTTTGTTCAG GGAAACCTTG AGAGAGAGTG CATAGAAGAA 
AGATGCAGTT TTGAAGAAGC ACGAGAAGTT TTTGAAAACA CTGAAAAAAC TACTGAATTT 
TGGAAGCAGT ATGTTGATGG AGATCAGTGT GAATCAAATC CTTGCTTAAA TGGTGGAATA 
TGCAAGGATG ATATTAATTC CTATGAATGT TGGTGCCAAG CTGGATTTGA AGGAAGGAAC 
TGTGAATTAG ATGCAACATG TAGCATTAAA AATGGCAGGT GTAAGCAGTT TTGTAAAAAC 
AGCCCTGATA ACAAGATAAT TTGTTCCTGC ACTGAGGGAT ACCAACTTGC AGAAGACCAG 
AAGTCCTGTG AACCAGCAGT TCCATTCCCA TGTGGAAGAG TTTCTGTTGC CTACAATTCT 
AAAAAGATCA CCCGTGCTGA GACTGTTTTT TCTAATACCG ACTATGGAAA TTCCACTGAA 
TTAATCCTGG ATGACATCAC CAACAGCACC ATTCTTGATA ACCTCACTGA AAATAGTGAA 
CCAATTAATG ACTTCACTCG AGTTGTTGGT GGAGAAAATG CGAAACCAGG TCAAATCCCT 
TGGCAGGTCA TTCTAAATGG TGAAATTGAG GCATTCTGTG GAGGCGCCAT CATTAATGAA 
AAATGGATTG TAACTGCTGC CCACTGTCTT AAACCTGGTG ATAAAATTGA GGTTGTTGCT 
GGTGAACATA ATATTGATGA GAAGGAAGAC ACAGAACAAA GGAGAAATGT GATTCGAACT 
ATCCCTCATC ACCAGTACAA TGCAACTATT AATAAGTATA GTCATGACAT TGCCTTGCTG 
GAACTGGATA AACCTTTAAT ACTAAACAGC TATGTAACAC CTATCTGTGT TGCCAATAAG 
GAATATACAA ATATCTTCCT CAAGTTTGGT TCTGGTTATG TGAGTGGCTG GGGGAAAGTC 
TTCAACAAAG GGAGACAGGC TTCCATTCTT CAGTACCTTA GAGTTCCACT GGTTGACCGA 
GCCACATGCC TTAGGTCCAC AAAATTCAGC ATCTATAACA ACATGTTCTG TGCAGGTTAC 
CGTGAAGGAG GCAAAGATTC ATGTGAAGGA GATAGTGGGG GACCCCATGT TACTGAAGTA 
GAAGGGACAA GTTTCTTAAC TGGCATTATT AGCTGGGGTG AAGAATGTGC AATGAAAGGC 
AAATATGGAA TATATACTAA GGTTTCCAGG TATGTCAACT GGATTAAGGA AAAAACAAAG 
CTAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

F9 ( XM_017601915.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457404.1 Rattus norvegicus coagulation factor IX (F9), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa63008
Clone ID Related Accession (Same CDS sequence)	XM_017601915.1
Accession Version	XM_017601915.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	coagulation factor IX isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGACG CTCCGGGTCT CATCCCCATC TTCCTTCTGG GCTATCTACT CAGCACTGAA 
TGTGCAGTTT TTCTTGATCG CGAAAATGCC ACCAAAATTC TTACCCGTCC AAAGAGATAT 
AACTCAGGGA AACTGGAAGA GTTTGTTCAG GGAAACCTTG AGAGAGAGTG CATAGAAGAA 
AGATGCAGTT TTGAAGAAGC ACGAGAAGTT TTTGAAAACA CTGAAAAAAC TACTGAATTT 
TGGAAGCAGT ATGTTGATGG AGATCAGTGT GAATCAAATC CTTGCTTAAA TGGTGGAATA 
TGCAAGGATG ATATTAATTC CTATGAATGT TGGTGCCAAG CTGGATTTGA AGGAAGGAAC 
TGTGAATTAG ATGCAACATG TAGCATTAAA AATGGCAGGT GTAAGCAGTT TTGTAAAAAC 
AGCCCTGATA ACAAGATAAT TTGTTCCTGC ACTGAGGGAT ACCAACTTGC AGAAGACCAG 
AAGTCCTGTG AACCAGCAGT TCCATTCCCA TGTGGAAGAG TTTCTGTTGC CTACAATTCT 
AAAAAGATCA CCCGTGCTGA GACTGTTTTT TCTAATACCG ACTATGGAAA TTCCACTGAA 
TTAATCCTGG ATGACATCAC CAACAGCACC ATTCTTGATA ACCTCACTGA AAATAGTGAA 
CCAATTAATG ACTTCACTCG AGTTGTTGGT GGAGAAAATG CGAAACCAGG TCAAATCCCT 
TGGCAGGGTG GTCAGCTTTT ACAGGAGCCT TGTTTGAGCA AATGTTTTGG TATGATCAAC 
TGGCAGAGCT CTTCTGACCC CTGGAGCAGC AGGACTAGCG TGAAAGTCAT AGTGTTTATG 
CATCAGGTCA TTCTAAATGG TGAAATTGAG GCATTCTGTG GAGGCGCCAT CATTAATGAA 
AAATGGATTG TAACTGCTGC CCACTGTCTT AAACCTGGTG ATAAAATTGA GGTTGTTGCT 
GGTGAACATA ATATTGATGA GAAGGAAGAC ACAGAACAAA GGAGAAATGT GATTCGAACT 
ATCCCTCATC ACCAGTACAA TGCAACTATT AATAAGTATA GTCATGACAT TGCCTTGCTG 
GAACTGGATA AACCTTTAAT ACTAAACAGC TATGTAACAC CTATCTGTGT TGCCAATAAG 
GAATATACAA ATATCTTCCT CAAGTTTGGT TCTGGTTATG TGAGTGGCTG GGGGAAAGTC 
TTCAACAAAG GGAGACAGGC TTCCATTCTT CAGTACCTTA GAGTTCCACT GGTTGACCGA 
GCCACATGCC TTAGGTCCAC AAAATTCAGC ATCTATAACA ACATGTTCTG TGCAGGTTAC 
CGTGAAGGAG GCAAAGATTC ATGTGAAGGA GATAGTGGGG GACCCCATGT TACTGAAGTA 
GAAGGGACAA GTTTCTTAAC TGGCATTATT AGCTGGGGTG AAGAATGTGC AATGAAAGGC 
AAATATGGAA TATATACTAA GGTTTCCAGG TATGTCAACT GGATTAAGGA AAAAACAAAG 
CTAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457404.1
CDS	54..1562
Translation	MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQGGQLLQEPCLSKCFGMINWQSSSDPWSSRTSVKVIVFMHQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT

Target ORF information:

RefSeq Version	XM_017601915.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus coagulation factor IX (F9), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601915.1

ORF Insert Sequence:

ATGGCAGACG CTCCGGGTCT CATCCCCATC TTCCTTCTGG GCTATCTACT CAGCACTGAA 
TGTGCAGTTT TTCTTGATCG CGAAAATGCC ACCAAAATTC TTACCCGTCC AAAGAGATAT 
AACTCAGGGA AACTGGAAGA GTTTGTTCAG GGAAACCTTG AGAGAGAGTG CATAGAAGAA 
AGATGCAGTT TTGAAGAAGC ACGAGAAGTT TTTGAAAACA CTGAAAAAAC TACTGAATTT 
TGGAAGCAGT ATGTTGATGG AGATCAGTGT GAATCAAATC CTTGCTTAAA TGGTGGAATA 
TGCAAGGATG ATATTAATTC CTATGAATGT TGGTGCCAAG CTGGATTTGA AGGAAGGAAC 
TGTGAATTAG ATGCAACATG TAGCATTAAA AATGGCAGGT GTAAGCAGTT TTGTAAAAAC 
AGCCCTGATA ACAAGATAAT TTGTTCCTGC ACTGAGGGAT ACCAACTTGC AGAAGACCAG 
AAGTCCTGTG AACCAGCAGT TCCATTCCCA TGTGGAAGAG TTTCTGTTGC CTACAATTCT 
AAAAAGATCA CCCGTGCTGA GACTGTTTTT TCTAATACCG ACTATGGAAA TTCCACTGAA 
TTAATCCTGG ATGACATCAC CAACAGCACC ATTCTTGATA ACCTCACTGA AAATAGTGAA 
CCAATTAATG ACTTCACTCG AGTTGTTGGT GGAGAAAATG CGAAACCAGG TCAAATCCCT 
TGGCAGGGTG GTCAGCTTTT ACAGGAGCCT TGTTTGAGCA AATGTTTTGG TATGATCAAC 
TGGCAGAGCT CTTCTGACCC CTGGAGCAGC AGGACTAGCG TGAAAGTCAT AGTGTTTATG 
CATCAGGTCA TTCTAAATGG TGAAATTGAG GCATTCTGTG GAGGCGCCAT CATTAATGAA 
AAATGGATTG TAACTGCTGC CCACTGTCTT AAACCTGGTG ATAAAATTGA GGTTGTTGCT 
GGTGAACATA ATATTGATGA GAAGGAAGAC ACAGAACAAA GGAGAAATGT GATTCGAACT 
ATCCCTCATC ACCAGTACAA TGCAACTATT AATAAGTATA GTCATGACAT TGCCTTGCTG 
GAACTGGATA AACCTTTAAT ACTAAACAGC TATGTAACAC CTATCTGTGT TGCCAATAAG 
GAATATACAA ATATCTTCCT CAAGTTTGGT TCTGGTTATG TGAGTGGCTG GGGGAAAGTC 
TTCAACAAAG GGAGACAGGC TTCCATTCTT CAGTACCTTA GAGTTCCACT GGTTGACCGA 
GCCACATGCC TTAGGTCCAC AAAATTCAGC ATCTATAACA ACATGTTCTG TGCAGGTTAC 
CGTGAAGGAG GCAAAGATTC ATGTGAAGGA GATAGTGGGG GACCCCATGT TACTGAAGTA 
GAAGGGACAA GTTTCTTAAC TGGCATTATT AGCTGGGGTG AAGAATGTGC AATGAAAGGC 
AAATATGGAA TATATACTAA GGTTTCCAGG TATGTCAACT GGATTAAGGA AAAAACAAAG 
CTAACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Titrating haemophilia B phenotypes using siRNA strategy: evidence that antithrombotic activity is separated from bleeding liability.
Thrombosis and haemostasis113(6)1300-11(2015 Jun)
Metzger JM,Tadin-Strapps M,Thankappan A,Strapps WR,DiPietro M,Leander K,Zhang Z,Shin MK,Levorse J,Desai K,Xu Y,Lai K,Wu W,Chen Z,Cai TQ,Jochnowitz N,Bentley R,Hoos L,Zhou Y,Sepp-Lorenzino L,Seiffert D,Andre P

How it all starts: Initiation of the clotting cascade.
Critical reviews in biochemistry and molecular biology50(4)326-36(2015)
Smith SA,Travers RJ,Morrissey JH

Nitrophorin 2, a factor IX(a)-directed anticoagulant, inhibits arterial thrombosis without impairing haemostasis.
Thrombosis and haemostasis104(6)1116-23(2010 Dec)
Mizurini DM,Francischetti IM,Andersen JF,Monteiro RQ

[Human coagulation factor IX gene therapy in murine hemophilia B by hydrodynamic delivery and site-specific genomic integration].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi31(5)294-9(2010 May)
Zhang L,Gu DS,DU WT,Liu PX,Lu SH,Yang RC

Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice.
Proceedings of the National Academy of Sciences of the United States of America107(15)7101-6(2010 Apr)
Verma D,Moghimi B,LoDuca PA,Singh HD,Hoffman BE,Herzog RW,Daniell H

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F9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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