Plp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Plp1
Entrez Gene ID	24943
Full Name	proteolipid protein 1
Synonyms	Plp
General protein information	Preferred Names proteolipid protein 1 Names myelin proteolipid protein Proteolipid protein (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) lipophilin proteolipid protein (myelin) 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq32

mRNA and Protein(s)

mRNA	Protein	Name
XM_017601914.1	XP_017457403.1	myelin proteolipid protein isoform X2
NM_030990.2	NP_112252.1	myelin proteolipid protein
XM_017601913.1	XP_017457402.1	myelin proteolipid protein isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PLP1	XP_001141683.1
Canis lupus familiaris (dog)	PLP1	NP_001013856.1
Bos taurus (cattle)	PLP1	NP_776574.2
Homo sapiens (human)	PLP1	NP_000524.3
Gallus gallus (chicken)	PLP1	NP_990608.1
	PLP1	XP_001087984.2
Mus musculus (house mouse)	Plp1	NP_035253.1
Rattus norvegicus (Norway rat)	Plp1	NP_112252.1
Xenopus tropicalis (tropical clawed frog)	plp1	NP_001027507.1

Gene Ontology
Bibliography

Related articles in PubMed

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.
Shimizu T, Wisessmith W, Li J, Abe M, Sakimura K, Chetsawang B, Sahara Y, Tohyama K, Tanaka KF, Ikenaka K
Glia65(6)917-930(2017 Jun)

The expression of PLP/DM-20 mRNA is restricted to the oligodendrocyte-lineage cells in the adult rat spinal cord.
Takeda K, Dezawa M, Kitada M
Histochemistry and cell biology145(2)147-61(2016 Feb)

Sex differences in myelin-associated protein levels within and density of projections between the orbital frontal cortex and dorsal striatum of adult rats: implications for inhibitory control.
Bayless DW, Daniel JM
Neuroscience300286-96(2015 Aug)

Perinatal methylmercury exposure perturbs the expression of Plp1 and Cnp splice variants in cerebellum of rat pups.
Padhi BK, Rosales M, Pelletier G
Neurotoxicology48223-30(2015 May)

The major myelin-resident protein PLP is transported to myelin membranes via a transcytotic mechanism: involvement of sulfatide.
Baron W, Ozgen H, Klunder B, de Jonge JC, Nomden A, Plat A, Trifilieff E, de Vries H, Hoekstra D
Molecular and cellular biology35(1)288-302(2015 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PLP and DM-20 mRNA expression is restricted to oligodendrocyte-lineage cells
Title: The expression of PLP/DM-20 mRNA is restricted to the oligodendrocyte-lineage cells in the adult rat spinal cord.

Protein levels of PLP were significantly greater in orbital frontal cortex (OFC) but not dorsal striatum (dSTR) of females as compared to males, suggesting that myelination is increased in OFC but similar in dSTR of females as compared to males
Title: Sex differences in myelin-associated protein levels within and density of projections between the orbital frontal cortex and dorsal striatum of adult rats: implications for inhibitory control.

Perinatal methylmercury exposure reduces the expression of Plp1 and Cnp splice variants in cerebellum of rat pups.
Title: Perinatal methylmercury exposure perturbs the expression of Plp1 and Cnp splice variants in cerebellum of rat pups.

PLP transport to the myelin membrane proceeds via a transcytotic mechanism mediated by sulfatide with a conformational alteration and transient partitioning of PLP into distinct membrane microdomains involved in biosynthetic and transcytotic transport
Title: The major myelin-resident protein PLP is transported to myelin membranes via a transcytotic mechanism: involvement of sulfatide.

PLP localization in the cell membrane is altered in myelination-inhibiting fibronectin substrates.
Title: The lateral membrane organization and dynamics of myelin proteins PLP and MBP are dictated by distinct galactolipids and the extracellular matrix.

The following Plp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Plp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07284	NM_030990.2 Latest version!	Rattus norvegicus proteolipid protein 1 (Plp1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa07284	XM_017601913.1 Latest version!	Rattus norvegicus proteolipid protein 1 (Plp1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa40103	XM_017601914.1 Latest version!	Rattus norvegicus proteolipid protein 1 (Plp1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Plp1 ( NM_030990.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_112252.1 Rattus norvegicus proteolipid protein 1 (Plp1), mRNA.

Price & Availability↑

CloneID	ORa07284
Clone ID Related Accession (Same CDS sequence)	NM_030990.2 , XM_017601913.1
Accession Version	NM_030990.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	myelin proteolipid protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB697155.1, M11185.1 and BC093596.1. On Mar 27, 2010 this sequence version replaced NM_030990.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC093596.1, M11185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689595, SAMEA2689600 [ECO:0000348] ##Evidence-Data-END##

ATGGGTTTGT TAGAGTGCTG TGCTAGATGT CTGGTAGGGG CCCCCTTTGC TTCCCTGGTG 
GCCACTGGAT TGTGTTTCTT TGGAGTGGCA CTGTTCTGTG GATGTGGACA TGAAGCTCTC 
ACTGGTACAG AAAAGTTAAT TGAGACCTAT TTCTCCAAAA ACTACCAGGA CTATGAGTAT 
CTCATTAATG TGATTCATGC TTTCCAGTAT GTCATCTATG GAACTGCCTC TTTCTTCTTC 
CTTTATGGGG CCCTCCTGCT GGCCGAGGGC TTCTACACCA CCGGCGCTGT CAGGCAGATC 
TTTGGCGACT ACAAGACCAC CATCTGCGGC AAGGGCCTGA GCGCAACGGT AACAGGGGGC 
CAGAAGGGGA GGGGTTCCAG AGGCCAACAT CAAGCTCATT CTTTGGAGCG GGTGTGTCAT 
TGTTTGGGAA AATGGCTAGG ACATCCCGAC AAGTTTGTGG GCATCACCTA TGCCCTGACT 
GTTGTATGGC TCCTGGTGTT TGCCTGCTCT GCTGTGCCTG TGTACATTTA CTTCAATACC 
TGGACCACCT GCCAGTCTAT TGCCTTCCCT AGCAAGACCT CTGCCAGTAT AGGCAGTCTC 
TGCGCTGATG CCAGAATGTA TGGTGTTCTC CCATGGAATG CTTTTCCTGG CAAGGTTTGT 
GGCTCCAACC TTCTGTCCAT CTGCAAAACA GCCGAGTTCC AAATGACCTT CCACCTGTTT 
ATTGCTGCAT TTGTGGGTGC TGCAGCCACA CTAGTTTCCC TGCTCACCTT CATGATTGCT 
GCCACTTACA ACTTTGCCGT CCTTAAACTC ATGGGCCGAG GCACCAAGTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112252.1
CDS	148..981
Translation	MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF

Target ORF information:

RefSeq Version	NM_030990.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus proteolipid protein 1 (Plp1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030990.2

ORF Insert Sequence:

ATGGGTTTGT TAGAGTGCTG TGCTAGATGT CTGGTAGGGG CCCCCTTTGC TTCCCTGGTG 
GCCACTGGAT TGTGTTTCTT TGGAGTGGCA CTGTTCTGTG GATGTGGACA TGAAGCTCTC 
ACTGGTACAG AAAAGTTAAT TGAGACCTAT TTCTCCAAAA ACTACCAGGA CTATGAGTAT 
CTCATTAATG TGATTCATGC TTTCCAGTAT GTCATCTATG GAACTGCCTC TTTCTTCTTC 
CTTTATGGGG CCCTCCTGCT GGCCGAGGGC TTCTACACCA CCGGCGCTGT CAGGCAGATC 
TTTGGCGACT ACAAGACCAC CATCTGCGGC AAGGGCCTGA GCGCAACGGT AACAGGGGGC 
CAGAAGGGGA GGGGTTCCAG AGGCCAACAT CAAGCTCATT CTTTGGAGCG GGTGTGTCAT 
TGTTTGGGAA AATGGCTAGG ACATCCCGAC AAGTTTGTGG GCATCACCTA TGCCCTGACT 
GTTGTATGGC TCCTGGTGTT TGCCTGCTCT GCTGTGCCTG TGTACATTTA CTTCAATACC 
TGGACCACCT GCCAGTCTAT TGCCTTCCCT AGCAAGACCT CTGCCAGTAT AGGCAGTCTC 
TGCGCTGATG CCAGAATGTA TGGTGTTCTC CCATGGAATG CTTTTCCTGG CAAGGTTTGT 
GGCTCCAACC TTCTGTCCAT CTGCAAAACA GCCGAGTTCC AAATGACCTT CCACCTGTTT 
ATTGCTGCAT TTGTGGGTGC TGCAGCCACA CTAGTTTCCC TGCTCACCTT CATGATTGCT 
GCCACTTACA ACTTTGCCGT CCTTAAACTC ATGGGCCGAG GCACCAAGTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Plp1 ( XM_017601913.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457402.1 Rattus norvegicus proteolipid protein 1 (Plp1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa07284
Clone ID Related Accession (Same CDS sequence)	NM_030990.2 , XM_017601913.1
Accession Version	XM_017601913.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	myelin proteolipid protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTTGT TAGAGTGCTG TGCTAGATGT CTGGTAGGGG CCCCCTTTGC TTCCCTGGTG 
GCCACTGGAT TGTGTTTCTT TGGAGTGGCA CTGTTCTGTG GATGTGGACA TGAAGCTCTC 
ACTGGTACAG AAAAGTTAAT TGAGACCTAT TTCTCCAAAA ACTACCAGGA CTATGAGTAT 
CTCATTAATG TGATTCATGC TTTCCAGTAT GTCATCTATG GAACTGCCTC TTTCTTCTTC 
CTTTATGGGG CCCTCCTGCT GGCCGAGGGC TTCTACACCA CCGGCGCTGT CAGGCAGATC 
TTTGGCGACT ACAAGACCAC CATCTGCGGC AAGGGCCTGA GCGCAACGGT AACAGGGGGC 
CAGAAGGGGA GGGGTTCCAG AGGCCAACAT CAAGCTCATT CTTTGGAGCG GGTGTGTCAT 
TGTTTGGGAA AATGGCTAGG ACATCCCGAC AAGTTTGTGG GCATCACCTA TGCCCTGACT 
GTTGTATGGC TCCTGGTGTT TGCCTGCTCT GCTGTGCCTG TGTACATTTA CTTCAATACC 
TGGACCACCT GCCAGTCTAT TGCCTTCCCT AGCAAGACCT CTGCCAGTAT AGGCAGTCTC 
TGCGCTGATG CCAGAATGTA TGGTGTTCTC CCATGGAATG CTTTTCCTGG CAAGGTTTGT 
GGCTCCAACC TTCTGTCCAT CTGCAAAACA GCCGAGTTCC AAATGACCTT CCACCTGTTT 
ATTGCTGCAT TTGTGGGTGC TGCAGCCACA CTAGTTTCCC TGCTCACCTT CATGATTGCT 
GCCACTTACA ACTTTGCCGT CCTTAAACTC ATGGGCCGAG GCACCAAGTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457402.1
CDS	343..1176
Translation	MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF

Target ORF information:

RefSeq Version	XM_017601913.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus proteolipid protein 1 (Plp1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601913.1

ORF Insert Sequence:

ATGGGTTTGT TAGAGTGCTG TGCTAGATGT CTGGTAGGGG CCCCCTTTGC TTCCCTGGTG 
GCCACTGGAT TGTGTTTCTT TGGAGTGGCA CTGTTCTGTG GATGTGGACA TGAAGCTCTC 
ACTGGTACAG AAAAGTTAAT TGAGACCTAT TTCTCCAAAA ACTACCAGGA CTATGAGTAT 
CTCATTAATG TGATTCATGC TTTCCAGTAT GTCATCTATG GAACTGCCTC TTTCTTCTTC 
CTTTATGGGG CCCTCCTGCT GGCCGAGGGC TTCTACACCA CCGGCGCTGT CAGGCAGATC 
TTTGGCGACT ACAAGACCAC CATCTGCGGC AAGGGCCTGA GCGCAACGGT AACAGGGGGC 
CAGAAGGGGA GGGGTTCCAG AGGCCAACAT CAAGCTCATT CTTTGGAGCG GGTGTGTCAT 
TGTTTGGGAA AATGGCTAGG ACATCCCGAC AAGTTTGTGG GCATCACCTA TGCCCTGACT 
GTTGTATGGC TCCTGGTGTT TGCCTGCTCT GCTGTGCCTG TGTACATTTA CTTCAATACC 
TGGACCACCT GCCAGTCTAT TGCCTTCCCT AGCAAGACCT CTGCCAGTAT AGGCAGTCTC 
TGCGCTGATG CCAGAATGTA TGGTGTTCTC CCATGGAATG CTTTTCCTGG CAAGGTTTGT 
GGCTCCAACC TTCTGTCCAT CTGCAAAACA GCCGAGTTCC AAATGACCTT CCACCTGTTT 
ATTGCTGCAT TTGTGGGTGC TGCAGCCACA CTAGTTTCCC TGCTCACCTT CATGATTGCT 
GCCACTTACA ACTTTGCCGT CCTTAAACTC ATGGGCCGAG GCACCAAGTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Plp1 ( XM_017601914.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457403.1 Rattus norvegicus proteolipid protein 1 (Plp1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa40103
Clone ID Related Accession (Same CDS sequence)	XM_017601914.1
Accession Version	XM_017601914.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	myelin proteolipid protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTTGT TAGAGTGCTG TGCTAGATGT CTGGTAGGGG CCCCCTTTGC TTCCCTGGTG 
GCCACTGGAT TGTGTTTCTT TGGAGTGGCA CTGTTCTGTG GATGTGGACA TGAAGCTCTC 
ACTGGTACAG AAAAGTTAAT TGAGACCTAT TTCTCCAAAA ACTACCAGGA CTATGAGTAT 
CTCATTAATG TGATTCATGC TTTCCAGTAT GTCATCTATG GAACTGCCTC TTTCTTCTTC 
CTTTATGGGG CCCTCCTGCT GGCCGAGGGC TTCTACACCA CCGGCGCTGT CAGGCAGATC 
TTTGGCGACT ACAAGACCAC CATCTGCGGC AAGGGCCTGA GCGCAACGTT TGTGGGCATC 
ACCTATGCCC TGACTGTTGT ATGGCTCCTG GTGTTTGCCT GCTCTGCTGT GCCTGTGTAC 
ATTTACTTCA ATACCTGGAC CACCTGCCAG TCTATTGCCT TCCCTAGCAA GACCTCTGCC 
AGTATAGGCA GTCTCTGCGC TGATGCCAGA ATGTATGGTG TTCTCCCATG GAATGCTTTT 
CCTGGCAAGG TTTGTGGCTC CAACCTTCTG TCCATCTGCA AAACAGCCGA GTTCCAAATG 
ACCTTCCACC TGTTTATTGC TGCATTTGTG GGTGCTGCAG CCACACTAGT TTCCCTGCTC 
ACCTTCATGA TTGCTGCCAC TTACAACTTT GCCGTCCTTA AACTCATGGG CCGAGGCACC 
AAGTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457403.1
CDS	349..1077
Translation	MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF

Target ORF information:

RefSeq Version	XM_017601914.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus proteolipid protein 1 (Plp1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601914.1

ORF Insert Sequence:

ATGGGTTTGT TAGAGTGCTG TGCTAGATGT CTGGTAGGGG CCCCCTTTGC TTCCCTGGTG 
GCCACTGGAT TGTGTTTCTT TGGAGTGGCA CTGTTCTGTG GATGTGGACA TGAAGCTCTC 
ACTGGTACAG AAAAGTTAAT TGAGACCTAT TTCTCCAAAA ACTACCAGGA CTATGAGTAT 
CTCATTAATG TGATTCATGC TTTCCAGTAT GTCATCTATG GAACTGCCTC TTTCTTCTTC 
CTTTATGGGG CCCTCCTGCT GGCCGAGGGC TTCTACACCA CCGGCGCTGT CAGGCAGATC 
TTTGGCGACT ACAAGACCAC CATCTGCGGC AAGGGCCTGA GCGCAACGTT TGTGGGCATC 
ACCTATGCCC TGACTGTTGT ATGGCTCCTG GTGTTTGCCT GCTCTGCTGT GCCTGTGTAC 
ATTTACTTCA ATACCTGGAC CACCTGCCAG TCTATTGCCT TCCCTAGCAA GACCTCTGCC 
AGTATAGGCA GTCTCTGCGC TGATGCCAGA ATGTATGGTG TTCTCCCATG GAATGCTTTT 
CCTGGCAAGG TTTGTGGCTC CAACCTTCTG TCCATCTGCA AAACAGCCGA GTTCCAAATG 
ACCTTCCACC TGTTTATTGC TGCATTTGTG GGTGCTGCAG CCACACTAGT TTCCCTGCTC 
ACCTTCATGA TTGCTGCCAC TTACAACTTT GCCGTCCTTA AACTCATGGG CCGAGGCACC 
AAGTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.
Glia65(6)917-930(2017 Jun)
Shimizu T,Wisessmith W,Li J,Abe M,Sakimura K,Chetsawang B,Sahara Y,Tohyama K,Tanaka KF,Ikenaka K

The expression of PLP/DM-20 mRNA is restricted to the oligodendrocyte-lineage cells in the adult rat spinal cord.
Histochemistry and cell biology145(2)147-61(2016 Feb)
Takeda K,Dezawa M,Kitada M

Sex differences in myelin-associated protein levels within and density of projections between the orbital frontal cortex and dorsal striatum of adult rats: implications for inhibitory control.
Neuroscience300286-96(2015 Aug)
Bayless DW,Daniel JM

Perinatal methylmercury exposure perturbs the expression of Plp1 and Cnp splice variants in cerebellum of rat pups.
Neurotoxicology48223-30(2015 May)
Padhi BK,Rosales M,Pelletier G

The major myelin-resident protein PLP is transported to myelin membranes via a transcytotic mechanism: involvement of sulfatide.
Molecular and cellular biology35(1)288-302(2015 Jan)
Baron W,Ozgen H,Klunder B,de Jonge JC,Nomden A,Plat A,Trifilieff E,de Vries H,Hoekstra D

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Plp1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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